Taiwan Partnering Award: Establishing a CHO Cell Expression System for Animal Vaccine Production
Lead Research Organisation:
University of Kent
Abstract
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| Description | We have developed mammalian cell expression vectors to aid the expression of proteins for vaccines. We have also helped the collaborators/partners in designing sequences that allow expression of their target proteins in mammalian cells. |
| Exploitation Route | The vectors and approaches can be used by others to design and express their own protein antigens and vaccine candidates. |
| Sectors | Education,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology |
| Description | The mammalian cell expression vectors have been used in a project with a commercial partner to help them express protein antigens to forward the development of their own diagnostic assays. |
| First Year Of Impact | 2022 |
| Sector | Healthcare,Manufacturing, including Industrial Biotechology |
| Impact Types | Economic |
| Title | Mammalian expression vectors |
| Description | We have developed and made mammalian expression vectors that can be used to express antigens for vaccines and diagnostics under this collaboration. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2022 |
| Provided To Others? | Yes |
| Impact | Impact will be realised in the coming years. Vectors to facilitate expression of proteins for vaccine and diagnostic purposes. |
| Description | Development of collaboration with Animal Vaccine Technology Group, National Pingtung University of Science and Technology, Taiwan |
| Organisation | National Taiwan University of Science and Technology |
| Country | Taiwan, Province of China |
| Sector | Academic/University |
| PI Contribution | We have begun to develop approaches to train those at the Institute in Taiwan in mammalian cell technology and other expression systems to express vaccines for animal use. This has been delayed due to COVID and at this stage we have discussed plans for the training and what will be involved, including hosting people at Kent for training. |
| Collaborator Contribution | We have begun to develop approaches to train those at the Institute in Taiwan in mammalian cell technology and other expression systems to express vaccines for animal use. This has been delayed due to COVID and at this stage we have discussed plans for the training and what will be involved, including hosting people at Kent for training. |
| Impact | Multi-disciplinary. Biology, chemistry, engineering. |
| Start Year | 2021 |
| Description | Open day 2023 |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Demonstration of work that was undertaken to provide diagnostic proteins for COVID tests and antigens. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Open day lab tours and research presentation |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Visit into research lab and discussion around development of vaccines and biotherapeutic proteins for the treatment of disease. Demonstrations of laboratory experiments and question and answer sessions. |
| Year(s) Of Engagement Activity | 2022 |