Characterizing the structure, function and drugability of tuberculosis proteins using Rv1127c as a paradigm
Lead Research Organisation:
University of Surrey
Department Name: Microbial & Cellular Sciences
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
| Description | This UK-US partnering award was designed to potentiate collaborative links between the applicants. This award funded the exchange of exchange of early career scientists between the University of Surrey and University of California Irvine and contributed to the preliminary data for a MRC Impact Acceleration Award and also a submission which is currently being considered. |
| Exploitation Route | This award has developed anti-TB compounds that we are currently filing patents on. |
| Sectors | Pharmaceuticals and Medical Biotechnology |
| Description | Development of lead compounds targeted to Mycobacterium tuberculosis |
| Amount | £86,024 (GBP) |
| Organisation | University of Surrey |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 06/2022 |
| End | 09/2023 |
| Description | Pint of Science |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | An interactive session on antibiotic resistance which included the history of antibiotics and phage therapies. We also included some of our research on tuberculosis. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Pint of Science |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Pint of Science: "The most unromantic way to die in the 21st Century" Public outreach event at Zero Carbon in Guildford. Very successful interactive session engaging the public by comparing the Covid-19 pandemic to the TB pandemic. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Podcast on Tuberculosis |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Podcast on tuberculosis: The forgotten pandemic Tuberculosis Genomics • • https://soundcloud.com/microbinfie/64-mycobacterium-tuberculosis-the-forgotten-pandemic • https://open.spotify.com/episode/0GQ6BEvntjwhQmwNdXeCDS?si=adb169a9def74827 • https://podcasts.apple.com/au/podcast/64-mycobacterium-tuberculosis-the-forgotten-pandemic/id1479852809?i=1000538531466 Episode 65 links: • https://open.spotify.com/episode/1zilnX4TA4VbC0LqELVbWU?si=ff3815a1cf2c4949 • https://soundcloud.com/microbinfie/65-genomics-of-mycobacterium-tuberculosis • https://podcasts.apple.com/au/podcast/65-genomics-of-mycobacterium-tuberculosis/id1479852809?i=1000539961245 531466 |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://open.spotify.com/episode/0GQ6BEvntjwhQmwNdXeCDS?si=adb169a9def74827 |
| Description | Stand at the Compton Fair |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | A stall att he Compton fair which included interactive activities aimed at different age groups. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Stand at the Compton Fair |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Compton Fair: Superbugs and Superfriends Successful stall for kids and adults with spin the wheel, antibiotic skittles, find your bacterial twin, microscopy and more Very popular as evidenced by the high footfall and was asked to run again in 2023 and recruited for the Farnham fair. |
| Year(s) Of Engagement Activity | 2022 |