Fighting bacterial plant disease through the development of biological control agents
Lead Research Organisation:
University of Warwick
Department Name: School of Life Sciences
Abstract
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Organisations
- University of Warwick (Lead Research Organisation)
- Swansea University (Collaboration)
- Malaysian Agricultural Research and Development Institute (Collaboration)
- National University of Malaysia (Collaboration)
- Malaysian Agricultural R & D Institute (Project Partner)
- National University of Malaysia (UKM) (Project Partner)
Publications
Jin S
(2025)
Protocol for generating protoplasts of Trichoderma koningiopsis and transformation of plasmid DNA
in STAR Protocols
| Description | International Institutional Partnership Fund |
| Amount | £24,522 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2024 |
| End | 06/2024 |
| Description | International Science Partnerships Fund |
| Amount | £158,400 (GBP) |
| Funding ID | 1203466293 |
| Organisation | British Council |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2024 |
| End | 11/2026 |
| Description | Swansea University |
| Organisation | Swansea University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | My research team and I provided expertise in Nanopore genome sequencing, assembly and annotation, as well as equipment to carry that out. |
| Collaborator Contribution | My partners provided the fungal strain to sequence, as well as the expertise and facilities for isolation and bioactivity testing of the strain. |
| Impact | We jointly published two research article in which we reported the characterisation of the genome and bioactivity of fungal strains: - Brooks S, Weaver JA, Klomchit A, Alharthi SA, Onlamun T, Nurani R, Vong TK, Alberti F and Greco C* (2024) Unveiling the potential of Daldinia eschscholtzii MFLUCC 19-0629 through bioactivity and bioinformatics studies for enhanced sustainable agriculture production. Frontiers in Chemical Biology 3: 1362147. doi: 10.3389/fchbi.2024.1362147. - Klomchit A, Calabon MS, Worabandit S, Weaver JA, Karima EM, Alberti F, Greco C,* and Mahanil S* (2024) Unveiling novel Neocosmospora species from Thai mangroves as potent biocontrol agents against Colletotrichum species. Journal of Applied Microbiology 135: lxae114. doi: https://doi.org/10.1093/jambio/lxae114. The collaboration is multidisciplinary as it spans over microbiology, analytical chemistry, bioinformatics, genomics. |
| Start Year | 2023 |
| Description | UKM and MARDI |
| Organisation | Malaysian Agricultural Research and Development Institute |
| Country | Malaysia |
| Sector | Public |
| PI Contribution | My research team contributed through expertise in genome sequencing and genome mining, genetic engineering of fungi and metabolite analysis. |
| Collaborator Contribution | My partners contributed through expertise in plant propagation inoculation and disease analysis, as well as training of staff. |
| Impact | doi.org/10.1016/j.xpro.2025.103668 |
| Start Year | 2023 |
| Description | UKM and MARDI |
| Organisation | National University of Malaysia |
| Country | Malaysia |
| Sector | Academic/University |
| PI Contribution | My research team contributed through expertise in genome sequencing and genome mining, genetic engineering of fungi and metabolite analysis. |
| Collaborator Contribution | My partners contributed through expertise in plant propagation inoculation and disease analysis, as well as training of staff. |
| Impact | doi.org/10.1016/j.xpro.2025.103668 |
| Start Year | 2023 |
| Description | Departmental seminar for the INBIOSIS Seminar Series IHSLS1_2024 at the National University of Malaysia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Approximately 30 people attended my seminar between in-person and online, including PG students, PDRAs, Research Assistants and academics. Following on from my talk, I had fruitful conversations with academics from the National University of Malaysia that may lead to future collaborations. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.ukm.my/inbiosis/en/webinars/ |
| Description | Departmental seminar in the School of Pharmacy of the University of East Anglia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Approximately 50 people attended my seminar, including PG students, PDRAs and academics. Following on from my talk, I had fruitful conversations with academics from UEA that may lead to future collaborations. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Invited speaker at the 1st Warwick BioSoc's Life Science Conference |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Undergraduate students |
| Results and Impact | Approximately 80 people attended my seminar which was followed by an expert panel discussion with the two other presenters aimed at answering questions from UG students. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.warwickbiosoc.co.uk/lifesciencesconference2023 |
| Description | iGEM 2023 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Undergraduate students |
| Results and Impact | The Warwick iGEM team 2023 made up of 7 undergraduate students worked on developing an improved whole-cell platform for the production of valuable monoterpenes, such as limonene and perillyl alcohol, whcih find application in many industries: food, cosmetics and cleaning products to name a few. As the PI of the IGEM team, I supervised and guided the team to engage with industry, stakeholders and professional practitioners to define the direction of the project. We also presented the outcomes of the project at the iGEM Jamboree (Paris), where the audience was primarily UG students, but also PG students, academics, and Industry/Business. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://2023.igem.wiki/warwick/index.html |
| Description | iGEM 2024 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Undergraduate students |
| Results and Impact | The Warwick iGEM team 2024 made up of 10 undergraduate students worked on developing a sustainable recycling process for the neodymium from electronic waste, via the engineering of bacteria that are naturally able to sense and take up lanthanides. As the PI of the IGEM team, I supervised and guided the team to engage with industry, stakeholders and professional practitioners to define the direction of the project. We also presented the outcomes of the project at the iGEM Jamboree (Paris), where the audience was primarily UG students, but also PG students, academics, and Industry/Business. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://2024.igem.wiki/warwick/index.html |