National Collection of Yeast Cultures
Lead Research Organisation:
QUADRAM INSTITUTE BIOSCIENCE
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
The project will characterise 100 commercially important yeast strains per annum with high precision and develop the marketing of NCYC services.
Planned Impact
unavailable
People |
ORCID iD |
| Ian Roberts (Principal Investigator) |
Publications
Bensasson D
(2019)
Diverse Lineages of Candida albicans Live on Old Oaks.
in Genetics
Bensasson D
(2018)
Diverse lineages of Candida albicans live on old oaks
Boundy-Mills KL
(2016)
Yeast culture collections in the twenty-first century: new opportunities and challenges.
in Yeast (Chichester, England)
Brown WR
(2011)
A Geographically Diverse Collection of Schizosaccharomyces pombe Isolates Shows Limited Phenotypic Variation but Extensive Karyotypic Diversity.
in G3 (Bethesda, Md.)
Chang C
(2012)
Corrigendum to "Candida theae sp. nov., a new anamorphic beverage-associated member of the Lodderomyces clade" [Int. J. Food Microbiol. 153 (2012) 10-14]
in International Journal of Food Microbiology
Chang CF
(2012)
Candida theae sp. nov., a new anamorphic beverage-associated member of the Lodderomyces clade.
in International journal of food microbiology
Davey RP
(2010)
TURNIP: tracking unresolved nucleotide polymorphisms in large hard-to-assemble regions of repetitive DNA sequence.
in Bioinformatics (Oxford, England)
Elliston A
(2015)
Methodology for enabling high-throughput simultaneous saccharification and fermentation screening of yeast using solid biomass as a substrate
in Biotechnology for Biofuels
Field SJ
(2015)
Identification of furfural resistant strains of Saccharomyces cerevisiae and Saccharomyces paradoxus from a collection of environmental and industrial isolates.
in Biotechnology for biofuels
Holland SL
(2011)
Candida argentea sp. nov., a copper and silver resistant yeast species.
in Fungal biology
| Description | Numerous yeast species new to science have been discovered and made available to the scientific community. New findings on important aspects of genome variation have also been published. The NCYC has developed into one of the largest, most biodiverse and best-characterised collections of yeast genetic resources in the world. |
| Exploitation Route | Yeasts are used extensively by the academic research community and are a mainstay of the food and beverage industries. They also have numerous important but less well-known applications in industrial biotechnology. The huge yeast gene pool assembled by the NCYC is in high demand for improved biorefinery production of bio-based fuels and chemicals. The ongoing NCYC genome sequencing project with the Earlham Institute is unlocking more of the genetic resources in the collection for commercial use and for improved understanding of the yeast component of the human microbiome and the natural environment. |
| Sectors | Agriculture Food and Drink Chemicals Energy Environment Manufacturing including Industrial Biotechology Culture Heritage Museums and Collections Pharmaceuticals and Medical Biotechnology |
| URL | http://www.ncyc.co.uk |
| Description | NCYC yeasts have been used by customers of the collection for diverse activities in education, research and commercial development. Around 600 enquiries have been dealt with each year by phone, email and web-site contacts. Two historic UK breweries (Lacons and Trumans) were revived in 2013 using yeasts preserved by the NCYC in the 1950s. NCYC yeasts have also been screened for novel traits of interest to industrial biotechnology e.g. improved production of renewable fuels and chemicals. Several hundred new yeast strains have been added to the collection in recent years and made available for screening for commercially valuable traits. The National Collection of Yeast Cultures (NCYC) in partnership with the IFR Biorefinery Centre has generated important new knowledge of the various forms of commercial yeast and how they are suited to their role in producing particular fermented products. Users worldwide have exploited NCYC yeasts in a wide variety of academic, biomedical and bioindustrial applications. Most recently NCYC yeasts have been used to help define the role of the yeast component of the human microbiome in health and disease. Improved microbial taxonomy has become recognised as vital to the future of microbiome research in general. The NCYC is recognised internationally as a leading centre of expertise in yeast taxonomy, genome sequencing and analysis. The NCYC National Capability activity was terminated in 2018 as a result of the changing strategic priorities of the Quadram Institute. |
| Sector | Agriculture, Food and Drink,Chemicals,Education,Energy,Environment,Healthcare,Manufacturing, including Industrial Biotechology,Culture, Heritage, Museums and Collections,Pharmaceuticals and Medical Biotechnology |
| Impact Types | Societal Economic |
| Description | Implementing the Nagoya Protocol on Access and Benefit Sharing in the UK |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Contribution to a national consultation/review |
| Impact | This regional, cross-sector workshop run by BEIS Regulatory Delivery addressed issues surrounding exploitation of global biodiversity by UK industry, ensuring all processes are compliant with the Nagoya Protocol. |
| Description | International Commission on Yeasts |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | Greater uptake and improved use of yeasts in industrial processes and in synthetic biology. |
| Description | Society of General Microbiology Eukaryotic Microbes Division |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | UK Biological Resource Collections Network Meeting, Public Health England, London SE1 8UG |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | This network influences the development, perception and exploitation of National biological resource collections amongst various stakeholder and user groups: Academic Institutions;General Public;Government Departments;Hospital / NHS Trusts;Independent Research Organisations;Industrial / Commercial;Public Research Organisations;Research Councils/ Institutes. |
| Description | BBSRC iCASE |
| Amount | £96,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2015 |
| End | 09/2019 |
| Description | Norwich Research Park DTP |
| Amount | £96,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2015 |
| End | 09/2019 |
| Description | 1002 Saccharomyces genomes project |
| Organisation | IRCAN |
| Department | Yeast Genomics |
| Country | France |
| Sector | Charity/Non Profit |
| PI Contribution | Selection of yeast strains for sequencing, discussions on analytical techniques and distribution of strain sets arising. |
| Collaborator Contribution | Sequencing and primary analysis. |
| Impact | This partnership increased the international standing and visibility of the UK National Collection of Yeast Cultures (NCYC), generating important new knowledge and numerous academic contacts and customers. The NCYC National Capability activity was terminated in 2018 as a result of the changing strategic priorities of the Quadram Institute. |
| Start Year | 2013 |
| Description | 1002 Saccharomyces genomes project |
| Organisation | University of Strasbourg |
| Country | France |
| Sector | Academic/University |
| PI Contribution | Selection of yeast strains for sequencing, discussions on analytical techniques and distribution of strain sets arising. |
| Collaborator Contribution | Sequencing and primary analysis. |
| Impact | This partnership increased the international standing and visibility of the UK National Collection of Yeast Cultures (NCYC), generating important new knowledge and numerous academic contacts and customers. The NCYC National Capability activity was terminated in 2018 as a result of the changing strategic priorities of the Quadram Institute. |
| Start Year | 2013 |
| Description | EU COST Action BIOFLAVOUR |
| Organisation | National Institute of Applied Sciences of Toulouse |
| Country | France |
| Sector | Academic/University |
| PI Contribution | Presentation at Yeast Flavour Workshop, Vevey, Switzerland. |
| Collaborator Contribution | Knowledge of flavour and fragrance industry |
| Impact | This partnership increased the international standing and visibility of the UK National Collection of Yeast Cultures (NCYC), generating numerous industrial contacts and customers. The NCYC National Capability activity was terminated in 2018 as a result of the changing strategic priorities of the Quadram Institute. |
| Start Year | 2013 |
| Description | 33rd International Specialist Symposium on Yeast, Cork, June 26th-29th 2017Â |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | International yeast conference |
| Year(s) Of Engagement Activity | 2017 |
| Description | Channel 4 Food Unwrapped TV programme. |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Ricochet TV production company visited with presenter Jimmy Doherty to film for a programme on the work of the National Collection of Yeast Cultures (NCYC), the various forms of commercial yeast and how they are suited to their role in producing particular fermented products. The NCYC National Capability activity was terminated in 2018 as a result of the changing strategic priorities of the Quadram Institute. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Microbiology Society Annual Meeting 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A session on non-coding RNA was organised which raised the profile of the NCYC's work on genome sequencing and analysis and which contributed to a BBSRC Responsive Mode (RM) research grant. Valuable contacts were cemented with Public Health England researchers working in the area of genome sequencing of medically-important yeast species. The meeting also increased the international standing and visibility of the UK National Collection of Yeast Cultures (NCYC), generating further contacts and customers.The NCYC National Capability activity was terminated in 2018 as a result of the changing strategic priorities of the Quadram Institute but the non-coding RNA (in this case rRNA) and genome sequencing work is expected to continue through the RM grant. |
| Year(s) Of Engagement Activity | 2017 |
| Description | National Fungus Day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | Yes |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | The NCYC stand attracted much interest from the general public, parents and children of all ages. A very active public engagement activity across all aspects of the Norwich Research Park, including the NCYC. |
| Year(s) Of Engagement Activity | 2013,2014 |
| Description | Pontifica Universidad Catolica Del Ecuador, Quito, Ecuador, Simposio Internacional Sobre Colecciones De Cultivos De Microorganismos, 7 - 9 Noviembe 2016 Â |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The presentation covered the activities of the National Collection of Yeast Cultures (NCYC), including the present knowledge of Global Yeast Biodiversity and its contribution to the Circular Economy. The NCYC National Capability activity was terminated in 2018 as a result of the changing strategic priorities of the Quadram Institute but its contribution to international environmental conservation efforts lives on through students inspired by such presentations e.g. resulting in this case in novel yeast collection and analysis from biodiverse environments in Ecuador and the Galapagos Islands. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Presentation to the Institute of Brewers and Distillers Meantime Brewery, Greenwich, London, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The activity publicised the work of the National Collection of Yeast Cultures (NCYC) in securing brewers' production yeasts and providing access to many more yeast varieties to an important industrial sector. The NCYC National Capability activity was terminated in 2018 as a result of the changing strategic priorities of the Quadram Institute. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Total Food 2017 - QIB, Norwich Research Park, UK 31/10/17 - 02/11/2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | International Food Conference |
| Year(s) Of Engagement Activity | 2017 |