Viral transmission by insect vectors
Lead Research Organisation:
THE PIRBRIGHT INSTITUTE
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
Understanding how viruses are transmitted is fundamental to controlling and ultimately eradicating a disease. This is particularly true for viruses with biological vectors where the life cycle of the virus often relies on the vector species, presenting more opportunities for disease control. Pirbright has an excellent track record in using biological data to inform models of transmission that directly inform policy on vaccination and culling. Moreover we have world leading facilities and expertise in studying insect vectors, including mosquitoes and midges, and their capacity to transmit viruses that cause disease. This unique combination allows Pirbright to react quickly to emerging threats, and we are alone in the UK in our ability to undertake fundamental basic research in an authentic disease context with the insect vector and the vertebrate disease host.
Arboviruses (arthropod-borne viruses) have a medical and veterinary impact in both developing and developed countries worldwide. Pirbright studies arbovirus transmission using state-of-the-art containment facilities paired with a cadre of specialist scientists and a track record that extends to over forty years of research in this area. Using these resources we will investigate factors that drive the emergence, spread and persistence of arboviruses in the wider environment with an emphasis on providing environmentally sound counter-measures for the control of disease. Our primary research targets will be Culicoides biting midges and mosquitoes. Culicoides are the most important vectors of livestock arboviruses in Europe, transmitting bluetongue and Schmallenberg viruses, while mosquito-borne arboviruses, such as dengue virus, incapacitate and kill more people each year than those transmitted by any other vector family.
We will examine the genetic and environmental drivers that enable arthropods to act as vectors of arboviruses with an emphasis on providing a range of tools that can be used to predict the probability of transmission. The specific methods used to study these vector groups will vary depending on the development and availability of key biological resources (e.g. suitable laboratory colonies; transcriptomes and genomes; associated cell lines) and informed by our existing track record, including working in high containment facilities. While in some arthropods (e.g. important mosquito vectors such as Aedes aegypti) these resources are vast and allow comparatively straightforward application of emerging technologies, other groups, in particular Culicoides are less tractable, largely due to the inability to produce relevant laboratory colony lines. Our aim is to provide a balanced approach that includes both cutting edge research of well characterised species of vector in the laboratory, combined with experiments based around less well characterised species of vector in the field. A major component of vector capacity is the ability of the arthropod to develop a transmissible infection with an arbovirus and will be a major focus of research within the ISP.
Arthropod vectors such as mosquitoes and Culicoides can provide highly efficient dispersal and transmission vehicles for viruses, but also provide a potential target for intervention. In this objective we will develop novel approaches to understanding and interrupting virus transmission by arthropods. We will target vectorial capacity both by developing means to reduce the number of vectors (“population suppression” methods) and through reducing individual vector competence (“refractory insects”). We will take a synthetic biology approach, using standardised approaches and sub-sections of the entire procedure to shorten each phase of the design-test-build cycle, and to produce more robust and flexible designs and genetic circuits. Despite the importance of arboviruses and their vectors, our understanding of critical aspects of vector biology remains poor, even for the most high-profile vector species. Similarly, arbovirus studies focus overwhelmingly on interaction with the vertebrate host, rather than with the arthropod. Work under this objective therefore comprises an integrated programme identifying and addressing specific knowledge gaps in fundamental understanding, as well as using current and project-derived tools and knowledge to assemble functional genetic circuits and systems for control.
Arboviruses (arthropod-borne viruses) have a medical and veterinary impact in both developing and developed countries worldwide. Pirbright studies arbovirus transmission using state-of-the-art containment facilities paired with a cadre of specialist scientists and a track record that extends to over forty years of research in this area. Using these resources we will investigate factors that drive the emergence, spread and persistence of arboviruses in the wider environment with an emphasis on providing environmentally sound counter-measures for the control of disease. Our primary research targets will be Culicoides biting midges and mosquitoes. Culicoides are the most important vectors of livestock arboviruses in Europe, transmitting bluetongue and Schmallenberg viruses, while mosquito-borne arboviruses, such as dengue virus, incapacitate and kill more people each year than those transmitted by any other vector family.
We will examine the genetic and environmental drivers that enable arthropods to act as vectors of arboviruses with an emphasis on providing a range of tools that can be used to predict the probability of transmission. The specific methods used to study these vector groups will vary depending on the development and availability of key biological resources (e.g. suitable laboratory colonies; transcriptomes and genomes; associated cell lines) and informed by our existing track record, including working in high containment facilities. While in some arthropods (e.g. important mosquito vectors such as Aedes aegypti) these resources are vast and allow comparatively straightforward application of emerging technologies, other groups, in particular Culicoides are less tractable, largely due to the inability to produce relevant laboratory colony lines. Our aim is to provide a balanced approach that includes both cutting edge research of well characterised species of vector in the laboratory, combined with experiments based around less well characterised species of vector in the field. A major component of vector capacity is the ability of the arthropod to develop a transmissible infection with an arbovirus and will be a major focus of research within the ISP.
Arthropod vectors such as mosquitoes and Culicoides can provide highly efficient dispersal and transmission vehicles for viruses, but also provide a potential target for intervention. In this objective we will develop novel approaches to understanding and interrupting virus transmission by arthropods. We will target vectorial capacity both by developing means to reduce the number of vectors (“population suppression” methods) and through reducing individual vector competence (“refractory insects”). We will take a synthetic biology approach, using standardised approaches and sub-sections of the entire procedure to shorten each phase of the design-test-build cycle, and to produce more robust and flexible designs and genetic circuits. Despite the importance of arboviruses and their vectors, our understanding of critical aspects of vector biology remains poor, even for the most high-profile vector species. Similarly, arbovirus studies focus overwhelmingly on interaction with the vertebrate host, rather than with the arthropod. Work under this objective therefore comprises an integrated programme identifying and addressing specific knowledge gaps in fundamental understanding, as well as using current and project-derived tools and knowledge to assemble functional genetic circuits and systems for control.
Planned Impact
unavailable
Organisations
- THE PIRBRIGHT INSTITUTE (Lead Research Organisation)
- University of Glasgow (Collaboration)
- International Livestock Research Institute (ILRI) (Collaboration)
- University of Zurich (Collaboration)
- Outreach Network for Gene Drive Research (Collaboration)
- Bernhard Nocht Institute for Tropical Medicine (Collaboration)
- Friedrich Loeffler Institute (Collaboration)
- Syngenta International AG (Collaboration)
- Centre for Genomic Regulation (CRG) (Collaboration)
- University of Malaya (Collaboration)
- IMPERIAL COLLEGE LONDON (Collaboration)
- University of California, Davis (Collaboration)
- Boston University School of Medicine (Collaboration)
- University of Tartu (Collaboration)
- University of Melbourne (Collaboration)
- Hebrew University of Jerusalem (Collaboration)
- Claude Bernard University Lyon 1 (UCBL) (Collaboration)
- National Institute of Genetics (Collaboration)
- National Health Research Institutes (NHRI) Taiwan (Collaboration)
- London School of Hygiene and Tropical Medicine (LSHTM) (Collaboration)
- THE PIRBRIGHT INSTITUTE (Collaboration)
- UNIVERSITY OF LIVERPOOL (Collaboration)
- Biomathematics and Statistics Scotland (BioSS) (Collaboration)
Publications
Ahmed A
(2020)
Risks and Challenges of Arboviral Diseases in Sudan: The Urgent Need for Actions.
in Viruses
Ahmed A
(2022)
Epidemics of Crimean-Congo Hemorrhagic Fever (CCHF) in Sudan between 2010 and 2020.
in Microorganisms
Alphey LS
(2020)
Opinion: Standardizing the definition of gene drive.
in Proceedings of the National Academy of Sciences of the United States of America
Anderson M
(2023)
AePUb promoter length modulates gene expression in Aedes aegypti
Anderson M
(2023)
Closing the gap to effective gene drive in Aedes aegypti by exploiting germline regulatory elements
in Nature Communications
Anderson MAE
(2023)
AePUb promoter length modulates gene expression in Aedes aegypti.
in Scientific reports
Anderson MAE
(2020)
Expanding the CRISPR Toolbox in Culicine Mosquitoes: In Vitro Validation of Pol III Promoters.
in ACS synthetic biology
Anderson MAE
(2024)
A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations.
in Nature communications
Anderson ME
(2019)
CRISPR/Cas9 gene editing in the West Nile Virus vector, Culex quinquefasciatus Say.
in PloS one
| Title | Additional file 2 of Emergence dynamics of adult Culicoides biting midges at two farms in south-east England |
| Description | Additional file 2: Figure S1. Air and soil temperature data for 2016-2018 for each farm site: daily mean and maximum air temperature (°C) (top and middle rows, respectively) and daily mean soil temperature at a depth of 3.5 cm (bottom row) for ON (left-hand column) and PW (right-hand column). Line colour indicates the year: 2016 (red); 2017 (blue); or 2018 (cyan). |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2022 |
| URL | https://springernature.figshare.com/articles/figure/Additional_file_2_of_Emergence_dynamics_of_adult... |
| Title | Additional file 2 of Emergence dynamics of adult Culicoides biting midges at two farms in south-east England |
| Description | Additional file 2: Figure S1. Air and soil temperature data for 2016-2018 for each farm site: daily mean and maximum air temperature (°C) (top and middle rows, respectively) and daily mean soil temperature at a depth of 3.5 cm (bottom row) for ON (left-hand column) and PW (right-hand column). Line colour indicates the year: 2016 (red); 2017 (blue); or 2018 (cyan). |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2022 |
| URL | https://springernature.figshare.com/articles/figure/Additional_file_2_of_Emergence_dynamics_of_adult... |
| Title | Additional file 3 of Emergence dynamics of adult Culicoides biting midges at two farms in south-east England |
| Description | Additional file 3: Figure S2. Observed and expected daily number of Culicoides biting midges caught in eight emergence traps at two farm sites in south-east England during 2016-2018. Each panel shows the observed daily mean (red) and the posterior median (blue dots) and 95% credible interval (shading) for the expected daily mean. The grey-shaded areas indicate when the samples were being collected from the trap |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2022 |
| URL | https://springernature.figshare.com/articles/figure/Additional_file_3_of_Emergence_dynamics_of_adult... |
| Title | Additional file 3 of Emergence dynamics of adult Culicoides biting midges at two farms in south-east England |
| Description | Additional file 3: Figure S2. Observed and expected daily number of Culicoides biting midges caught in eight emergence traps at two farm sites in south-east England during 2016-2018. Each panel shows the observed daily mean (red) and the posterior median (blue dots) and 95% credible interval (shading) for the expected daily mean. The grey-shaded areas indicate when the samples were being collected from the trap |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2022 |
| URL | https://springernature.figshare.com/articles/figure/Additional_file_3_of_Emergence_dynamics_of_adult... |
| Title | Additional file 4 of Emergence dynamics of adult Culicoides biting midges at two farms in south-east England |
| Description | Additional file 4: Figure S3. Observed and expected daily number of Culicoides obsoletus/scoticus females caught in eight emergence traps at two farm sites in south-east England during 2016-2018. Each panel shows the observed daily mean (red) and the posterior median (blue dots) and 95% credible interval (shading) for the expected daily mean. The grey-shaded areas indicate when the samples were being collected from the trap. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2022 |
| URL | https://springernature.figshare.com/articles/figure/Additional_file_4_of_Emergence_dynamics_of_adult... |
| Title | Additional file 4 of Emergence dynamics of adult Culicoides biting midges at two farms in south-east England |
| Description | Additional file 4: Figure S3. Observed and expected daily number of Culicoides obsoletus/scoticus females caught in eight emergence traps at two farm sites in south-east England during 2016-2018. Each panel shows the observed daily mean (red) and the posterior median (blue dots) and 95% credible interval (shading) for the expected daily mean. The grey-shaded areas indicate when the samples were being collected from the trap. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2022 |
| URL | https://springernature.figshare.com/articles/figure/Additional_file_4_of_Emergence_dynamics_of_adult... |
| Title | Additional file 5 of Emergence dynamics of adult Culicoides biting midges at two farms in south-east England |
| Description | Additional file 5: Figure S4. Observed and expected daily number of Culicoides obsoletus males caught in eight emergence traps at two farm sites in south-east England during 2016-2018. Each panel shows the observed daily mean (red) and the posterior median (blue dots) and 95% credible interval (shading) for the expected daily mean. The grey-shaded areas indicate when the samples were being collected from the trap |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2022 |
| URL | https://springernature.figshare.com/articles/figure/Additional_file_5_of_Emergence_dynamics_of_adult... |
| Title | Additional file 5 of Emergence dynamics of adult Culicoides biting midges at two farms in south-east England |
| Description | Additional file 5: Figure S4. Observed and expected daily number of Culicoides obsoletus males caught in eight emergence traps at two farm sites in south-east England during 2016-2018. Each panel shows the observed daily mean (red) and the posterior median (blue dots) and 95% credible interval (shading) for the expected daily mean. The grey-shaded areas indicate when the samples were being collected from the trap |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2022 |
| URL | https://springernature.figshare.com/articles/figure/Additional_file_5_of_Emergence_dynamics_of_adult... |
| Description | The Viral Transmission by Insect Vectors ISPG component grant has two primary objectives: (1) examine the influence of vector competence in the spread of arboviruses and (2) develop new tools for controlling the spread of viruses by arthropod vectors. Key findings to date: Bluetongue: animal experiments demonstrated that reduced vector competence has led to reduced spread of a re-emerging bluetongue virus (BTV) strain in northern Europe (1). We developed three-dimensional imaging of replicating virus distribution in Culicoides and showed that the salivary accessory glands (which among haematophagous insects are unique to Culicoides) are primary sites of BTV replication (1). We also used our new imaging techniques to characterised the temporal dynamics of BTV replication in the midgut, the initial site of BTV replication in the vector, in unprecedented detail (1). We promoted standardised approaches for testing vector competence - lack of such standardisation has inhibited comparative analysis of studies (1). We are also improving genomic resources for the study of Culicoides in addition to identifying a suite of genes associated with infection with arboviruses (1,2). Analysing ancestral and reassortant BTV field strains highlighted the influence of certain viral genome segments in enhancing BTV replication in Culicoides as well as clinical disease in sheep (1). Identifying viral genes that enable enhanced virus replication in certain Culicoides species is a critical step in understanding viral traits observed in the field. We have conducted surveys of Culicoides populations across the UK for the endosymbionts Cardinium, Rickettsia and Wolbachia (know to influence vector competence in other systems), and observed a very low prevalence of these endosymbionts in these populations (1). Genetic control of virus vectors: new promoters driving gene expression in Anopheles gambiae embryos identified and validated in vivo (2). New male-specific A. gambiae cell line isolated and established and new sex-specific long-read RNA-seq data from A. gambiae generated (2). We described femaleless, a gene highly conserved across Anopheles mosquitoes, which is a vital regulator of the sex determination and dosage compensation pathways, and necessary for the survival of female mosquitoes (2). These studies aim at producing male-only mosquito populations for genetics-based control of mosquito vectors in the field. We identified numerous open chromatin regions indicative of genome-wide regulatory activity that drives transcription of genes in the early embryos of the Anopheles gambiae mosquitoes and validated five of these, allowing constructs to drive expression of various effector genes during early mosquito development (2). These studies have been complemented by publications examining potential use of gene drives in the control and eradication of mosquito populations (2). We analysed resistance management for homing-based gene drives in the control of disease vectors (2) and developed key components and principles for such approaches. Lumpy-skin disease virus (LSDV): Challenge experiments demonstrated four different biting insects can transmit LSDV, with different virus retention times, and that insects feeding on lesions are much more likely to transmit the virus (1). Modelling indicated Stomoxys calcitrans as potentially important vectors (1). These findings help inform policy advice. Rift Valley fever virus (RVFV): Impact of vaccination and stamping out on RVF in Europe were modelled, identifying knowledge gaps and informing policy. We have identified major mosquito immune responses to RVFV infection using mosquito cells (1). Flaviviruses: We identified NF-?B pathways as novel antiviral innate immune pathways that respond to viral infection and model virus-like double-stranded RNAs in Aedes aegypti cells, suggesting that these pathways play an underappreciated role in influencing vector competence (1). We also found that flaviviruses suppress the activation of these antiviral responses, which may influence viral transmission (1). To date this ISPG project has resulted in the publication of over 88 publications and over 190 engagement activities, in addition to providing evidence used in governmental assessments of genetic modification techniques and the impact of climate change on vector-borne diseases. |
| Exploitation Route | Each of the key findings will be pursued further. Correlating specific BTV genome segments with replication advantage in Culicoides will inform future risk assessments of emerging BTV strains, and also help identify key viral factors and mechanisms that drive infection and replication success in Culicoides. Visualisation of BTV infection in Culicoides tissues will help identify barriers to infection and the impact of arbovirus infection on Culicoides physiology, behaviour and transmission. We will continue to develop strategies for introgressing exogenous genes into wild mosquito populations - a method with considerable potential application for human health, agriculture and conservation - and the necessary molecular and genetic components and methods for that, also genetic means to manipulate vector competence. The models developed for transmission of RVFV were used to assess the potential for spread in Europe and the impact of control measures (in particular, vaccination and stamping out). The findings were reported to the European Commission via scientific opinions produced by the European Food Safety Authority. We will continue to investigate how viruses are detected by Aedes aegypti mosquito NF-?B pathways and how this influences vector competence, as well as determining how the modulation of these pathways enables viruses to switch to using new vector species (potentially leading to viral emergence into new vertebrate hosts). |
| Sectors | Agriculture Food and Drink Environment Healthcare Pharmaceuticals and Medical Biotechnology |
| Description | Scientists engaged on this project, and project outputs, have influenced policy around arboviruses and vector-born disease in several ways. Scientists (SC and SG) served on a Science Advisory Group for Emergencies simulation exercise for a zoonotic virus outbreak in the UK providing evidence derived from ISPG aims. SC is currently OIE expert for African horse sickness virus and bluetongue virus (BTV) and the Pirbright team (CB, SC, SG, KD), is the main source for underpinning scientific evidence used by Defra during Culicoides-borne arbovirus incursions. This has included responding to recent imports of BTV viraemic animals in 2017 and 2018. The models developed to describe the spread of lumpy skin disease virus (LSDV) within and between cattle herds have been used to inform disease control policy following outbreaks of LSDV in the Balkans. Specifically, they have been used to assess the duration of vaccination programmes to prevent re-emergence of the disease in an affected country and to inform the design of surveillance to detect re-emergence, detect incursions from neighbouring countries and to regain disease-free status. These results have been communicated to the European Commission and affected countries via the European Food Safety Authority (EFSA). Again through EFSA, we have been providing advice to the European Commission on Rift Valley Fever virus. To date this has focused on providing information about the virus and its transmission and on assessing the probability of RVFV persisting in Mayotte and on the potential for spread to or from Mayotte via wind-borne dispersal of RVFV-infected mosquitoes. The models developed for transmission of RVFV were used to assess the potential for spread in Europe and the impact of control measures (in particular, vaccination and stamping out). The findings were reported to the European Commission via scientific opinions produced by the European Food Safety Authority. A recent EFSA consultation document on regulation of gene drives "Evaluation of existing EFSA guidelines for their adequacy for the molecular characterisation and environmental risk assessment of genetically modified insects with synthetically engineered gene drives" (EFSA 2020) cites around 30 of papers from project scientists, including several from this award. We have also worked with others in the field to develop and publish shared expectations and commitments from developers and others regarding these emerging genetic technologies, e.g. Long et al (2020) Core commitments for field trials of gene drive organisms. Science 370 1417-9 and Alphey et al (2020) Standardizing the definition of gene drive PNAS 117:30864-7. |
| Sector | Agriculture, Food and Drink,Environment,Healthcare |
| Impact Types | Economic Policy & public services |
| Description | Contributed to Chief Medical Officers report- Genomics section |
| Geographic Reach | Europe |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| URL | https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/6310... |
| Description | Contribution to guidance document "Safe working with arthropods: Containment and control for work with uninfected, infected and transgenic animals in research" |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Contributed to a document providing the first detailed guidance by the relevant national professional body (ISTR, the Institute for Safety in Technology and Research) on compliance with HSE requirements for working with exotic, GM and infected arthropods. |
| URL | https://www.pirbright.ac.uk/news/2017/04/first-industry-guidance-safe-working-arthropods-and-gm-inse... |
| Description | International Society for Neglected Tropical Diseases Dengue Advisory Group |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| URL | https://www.isntd.org/dengue-advisory-group |
| Description | Invited expert at OIE Regional Consultation webinars on lumpy skin disease for Asia and the Pacific |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| URL | https://rr-asia.oie.int/en/events/lumpy-skin-disease-webinar-series/ |
| Description | MSc research training |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | The immediate outcome of this impact activity is that these Masters students went on to the following subsequent career destinations: PhD programme: 2 students Technical position in research institution: 1 student |
| Description | Member of Defra Science Advisory Council Exotic and Emerging Diseases (SAC-ED) subcommittee |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | More effective anticipation of and response to disease outbreaks reducing their impact on the farming and wider community |
| Description | Microbiology Society Members Panel |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | A number of initiatives have been implemented that have made activities within the Microbiology Society more accessible to historically marginalised groups, for example the promotion of pronouns, changes to alcohol provision to make conference sessions more accessible to people who cannot be around alcohol, introduction of a knowledge-exchange forum as a new session at the Society's annual conference, improved equality, diversity and inclusion training, introduction of quiet rooms for neurodiverse scientists. |
| URL | https://microbiologysociety.org/why-microbiology-matters/council-governance/standing-panels/members-... |
| Description | Organised seminar series on Sequencing, Virus Evolution and Molecular Biology at Pirbright (with Luca Ferretti and Graham Freimanis) |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | PhD research training |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | The concrete outcomes of this PhD training was the skills learnt by the respective students while under my guidance. Their immediate destinations after graduating were: Postdoctoral academic research (US): one student Postdoctoral academic research (UK): one student |
| Description | RCUK Engagement workshop, Cosener's House, 20-21 April 2017 |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Training of Masters students (Imperial College London) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | The students gained specialist knowledge in vector-borne diseases - their transmission and emergence potential. Students came from multiple countries across the world and will take this knowledge back with them in the future. |
| Description | Training of medical students (University of Oxford) |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | The students on this medical degree programme were trained in tropical medicine. |
| Description | University of Oxford (medical students training) |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | The students gained an understanding for important tropical diseases that they may encounter in patients when they begin work in the clinic. Since these diseases are not endemic to the UK they would otherwise not have gained this information. |
| URL | https://www.ox.ac.uk |
| Description | Zika pandemic preparedness ten-year plan consultation (Wellcome Trust/WHO) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | A One Health Approach to Alkhumra Haemorrhagic Fever Virus Species Tropism, Pathogenesis and Epidemiology |
| Amount | £99,082 (GBP) |
| Organisation | The Pirbright Institute |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 09/2022 |
| End | 04/2026 |
| Description | Application of field-deployable surveillance tool to enhance molecular xenomonitoring of multiple vector borne diseases |
| Amount | £4,675,662 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2022 |
| End | 09/2023 |
| Description | Application of molecular xenomonitoring in a lateral flow test format for multiplexed monitoring of vector-borne viruses and their animal reservoirs and insect vectors in low-income settings |
| Amount | £49,015 (GBP) |
| Funding ID | IAA2149 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2024 |
| End | 03/2025 |
| Description | BBSRC GCRF Impact Accelerator Award |
| Amount | £5,000 (GBP) |
| Funding ID | BB/GCRF-IAA/17/16 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2018 |
| End | 02/2018 |
| Description | BBSRC Responsive Mode IPA |
| Amount | £302,086 (GBP) |
| Funding ID | BB/R002606/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2018 |
| End | 06/2019 |
| Description | BBSRC responsive mode funding |
| Amount | £356,484 (GBP) |
| Funding ID | BB/T005173/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 12/2021 |
| Description | BBSRC-funded Oxford Doctoral Training Partnership in vivo skills award |
| Amount | £15,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2020 |
| End | 06/2021 |
| Description | Biotechnology and Biological Sciences Research Council (BBSRC) and University of Oxford joint Doctoral Training Project |
| Amount | £100,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2018 |
| End | 08/2022 |
| Description | Components of the Medea gene drive system in a mosquito Aedes aegypti |
| Amount | £758,098 (GBP) |
| Funding ID | BB/S001964/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2019 |
| End | 10/2022 |
| Description | Conserved molecular mechanisms of replication for mosquito-borne flaviviruses |
| Amount | $199,350 (USD) |
| Funding ID | 1R21AI168716-01 |
| Organisation | National Institute of Allergy and Infectious Diseases (NIAID) |
| Sector | Public |
| Country | United States |
| Start | 02/2022 |
| End | 01/2024 |
| Description | DARPA PREEMPT |
| Amount | $2,700,000 (USD) |
| Organisation | Defense Advanced Research Projects Agency (DARPA) |
| Sector | Public |
| Country | United States |
| Start | 09/2018 |
| End | 03/2022 |
| Description | Dengue haemorrhage: a novel role for perivascular cells |
| Amount | £74,137 (GBP) |
| Organisation | University of Surrey |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 09/2021 |
| End | 09/2024 |
| Description | Floid Cell imager (X2) |
| Amount | £24,459 (GBP) |
| Organisation | The Pirbright Institute |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 11/2021 |
| End | 03/2022 |
| Description | GCRF Networks in Vector Ecology |
| Amount | £1,035,634 (GBP) |
| Funding ID | BB/R005362/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2017 |
| End | 06/2020 |
| Description | Global characterisation of interlinked mosquito immune networks |
| Amount | £38,936 (GBP) |
| Funding ID | BB/W510725/1 |
| Organisation | The Pirbright Institute |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 07/2021 |
| End | 03/2022 |
| Description | H2020 work programme topic 9 Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy, work topic SFS-10-2017 Research and approaches for emerging diseases in plants and terrestrial livestock |
| Amount | € 5,986,250 (EUR) |
| Organisation | European Commission H2020 |
| Sector | Public |
| Country | Belgium |
| Start | 04/2018 |
| End | 04/2023 |
| Description | Identification of innate immune genes in Aedes aegypti |
| Amount | £10,000 (GBP) |
| Organisation | The Pirbright Institute |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 08/2022 |
| End | 03/2023 |
| Description | International Workshops |
| Amount | £10,000 (GBP) |
| Funding ID | BB/R021198/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 05/2019 |
| Description | Microbiology Society - travel award |
| Amount | £420 (GBP) |
| Funding ID | GA001689 |
| Organisation | Microbiology Society |
| Sector | Learned Society |
| Country | United Kingdom |
| Start | 08/2019 |
| End | 09/2019 |
| Description | Society Conference Grant |
| Amount | £380 (GBP) |
| Organisation | Microbiology Society |
| Sector | Learned Society |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 04/2022 |
| Description | Society Conference Grant |
| Amount | £380 (GBP) |
| Organisation | Microbiology Society |
| Sector | Learned Society |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 04/2022 |
| Description | The Pirbright Institute - University of Surrey PhD studentship |
| Amount | £100,000 (GBP) |
| Organisation | The Pirbright Institute |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 09/2019 |
| End | 03/2023 |
| Description | The role of perivascular cell dysfunction in hepatic complications of dengue haemorrhagic fever |
| Amount | £589,017 (GBP) |
| Funding ID | MR/X009203/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2024 |
| End | 01/2027 |
| Description | Using machine learning to identify the molecular determinants of vector-borne transmission in viruses |
| Amount | £110,327 (GBP) |
| Organisation | The Pirbright Institute |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 09/2024 |
| End | 04/2028 |
| Title | A male-specific cell line from a mosquito Anopheles gambiae |
| Description | A new male-specific cell line from a mosquito Anopheles gambiae has been isolated from sexed neonate larvae. To our knowledge this is the only cell line derived exclusively from male mosquitoes. |
| Type Of Material | Cell line |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | The cell line will greatly facilitate studies on components of the sex determination pathway and of dosage compensation machinery in mosquitoes. There are only several cell lines derived from Anopheles gambiae available and these are female-like. Over-expression of genes involved in male sex determination or dosage compensation is detrimental to female cells, hence use of male-derived cells is necessary for such studies. The cell line will become available upon acceptance of a manuscript describing characterization of that cell line. |
| Title | CRISPR knockouts of RNAi pathway components in Aedes aegypti Aag2 cells |
| Description | We developed a number of CRISPR knockout cell lines based on the Aedes aegypti Aag2 cell line. These cell lines have facilitated research on virus-host interactions in the mosquito vector, and are also facilitating studies into the fundamental nature of antiviral responses of mosquitoes. |
| Type Of Material | Cell line |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | We have distributed these cell lines to numerous research groups across the world, including in the US, many European countries and research groups across the UK. These groups have made significant discoveries using these tools, many of which are published. Some of these cell lines were also made available via ECACC (https://www.culturecollections.org.uk/collections/ecacc.aspx). |
| Title | Ex vivo skin model |
| Description | An in vitro model of bovine skin has been developed, designed to allow feeding of dipteran species. |
| Type Of Material | Model of mechanisms or symptoms - in vitro |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | This has already reduced the number of procedures carried out on cattle in our studies by providing an alternative to insects feeding on cattle. |
| Title | Microbiopsy method |
| Description | We have optimised a technique for cutaneous skin biopsy of cattle. |
| Type Of Material | Model of mechanisms or symptoms - mammalian in vivo |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | The microbiopsy technique is less invasive and less painful than the traditional biopsy technique |
| Title | Reverse genetics system for Rift Valley fever virus and other bunyaviruses |
| Description | We developed a T7-based reverse genetics system for RVFV including for the rescue of a panel of novel reporter viruses. Using this system, virus will be rescued by transfection of cells with three plasmids encoding the three genome segments, driven by T7 polymerase which needs to be provided (e.g. stably or transiently expressed). Helper plasmids are no longer needed. RVFV-specific sequences can be easily replaced by those of other bunyaviruses of interest. |
| Type Of Material | Technology assay or reagent |
| Year Produced | 2022 |
| Provided To Others? | Yes |
| Impact | This research tool is used by my team and by collaborators and will be made available to the research community on request without MTA. The development of this system has reduced our reliance on other systems with restricted use (by MTA) and thus increases the UK's preparedness for bunyaviruses emergences as well as provides opportunities for commercial use. |
| Title | Additional file 4 of Culicoides species composition and molecular identification of host blood meals at two zoos in the UK |
| Description | Additional file 4: Dataset 1. Full data set of collected Culicoides including site, trap location, collection date and morphological identification. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/Additional_file_4_of_Culicoides_species_composition_and... |
| Title | Additional file 4 of Culicoides species composition and molecular identification of host blood meals at two zoos in the UK |
| Description | Additional file 4: Dataset 1. Full data set of collected Culicoides including site, trap location, collection date and morphological identification. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/Additional_file_4_of_Culicoides_species_composition_and... |
| Title | Additional file 5 of Culicoides species composition and molecular identification of host blood meals at two zoos in the UK |
| Description | Additional file 5: Table S1. Species composition of blood-fed Culicoides caught in traps. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/Additional_file_5_of_Culicoides_species_composition_and... |
| Title | Additional file 5 of Culicoides species composition and molecular identification of host blood meals at two zoos in the UK |
| Description | Additional file 5: Table S1. Species composition of blood-fed Culicoides caught in traps. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/Additional_file_5_of_Culicoides_species_composition_and... |
| Title | Additional file 6 of Culicoides species composition and molecular identification of host blood meals at two zoos in the UK |
| Description | Additional file 6: Table S2. Results of blood meal analysis of Culicoides collected from ZSL London Zoo and Whipsnade Zoo. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/Additional_file_6_of_Culicoides_species_composition_and... |
| Title | Additional file 6 of Culicoides species composition and molecular identification of host blood meals at two zoos in the UK |
| Description | Additional file 6: Table S2. Results of blood meal analysis of Culicoides collected from ZSL London Zoo and Whipsnade Zoo. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/Additional_file_6_of_Culicoides_species_composition_and... |
| Title | Additional file 7 of Culicoides species composition and molecular identification of host blood meals at two zoos in the UK |
| Description | Additional file 7: Table S3. Comparison of different models for the number of Culicoides biting midges caught at London and Whipsnade zoos. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/Additional_file_7_of_Culicoides_species_composition_and... |
| Title | Additional file 7 of Culicoides species composition and molecular identification of host blood meals at two zoos in the UK |
| Description | Additional file 7: Table S3. Comparison of different models for the number of Culicoides biting midges caught at London and Whipsnade zoos. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/Additional_file_7_of_Culicoides_species_composition_and... |
| Title | Additional file 7 of Emergence dynamics of adult Culicoides biting midges at two farms in south-east England |
| Description | Additional file 7: Data S1. Full data set of collected Culicoides including site, trap location, collection date and morphological identification |
| Type Of Material | Database/Collection of data |
| Year Produced | 2022 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/dataset/Additional_file_7_of_Emergence_dynamics_of_adul... |
| Title | Additional file 7 of Emergence dynamics of adult Culicoides biting midges at two farms in south-east England |
| Description | Additional file 7: Data S1. Full data set of collected Culicoides including site, trap location, collection date and morphological identification |
| Type Of Material | Database/Collection of data |
| Year Produced | 2022 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/dataset/Additional_file_7_of_Emergence_dynamics_of_adul... |
| Title | Additional file 8 of Culicoides species composition and molecular identification of host blood meals at two zoos in the UK |
| Description | Additional file 8: Table S4. Effect of seasonality, year, temperature and trap location on the number of Culicoides collected. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/Additional_file_8_of_Culicoides_species_composition_and... |
| Title | Additional file 8 of Culicoides species composition and molecular identification of host blood meals at two zoos in the UK |
| Description | Additional file 8: Table S4. Effect of seasonality, year, temperature and trap location on the number of Culicoides collected. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/Additional_file_8_of_Culicoides_species_composition_and... |
| Title | GCRF portal on transboudary diseases |
| Description | The Integrative Biology and Bioinformatics group is developing a GCRF-funded Portal on Transboundary Diseases. It will be an easy way for all scientists, and those from LMI countries in particular, to access data about several viral diseases generated at Pirbright. The portal will be country-based, presenting the user with a map and dispatching them to the information relevant to the selected region. From that information the user will be able to reach specialised websites for diseases present in the country, and data generated at Pirbright (such as sequences for FMDV, several Capripox viruses, and ASFV). Sequences relevant to the portal are currently being generated. Bioinformatics workflows are hosted on the IBB cluster, and have been implemented as REST web services so as to be decoupled from the web interface. The web interface is currently being developed with the help of a specialised company. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | The portal will benefit scientists from LMI countries, and all scientist, allowing them to access/download genetic and other data relevant to animal diseases present in a country of choice and studied and Pirbright. Some of the data (for instance the FMDV data generated by the World Reference Lab) is already use to inform policy at international level. Being able to access information in a systematic way will increase the potential for it to be put to good use. |
| Title | Genome browser for mosquitos at different developmental stages |
| Description | The database integrates and makes available the results of the bioinformatics analysis of several experiments involving high-throughput sequencing of mosquito cells at different developmental stages generated within the Vector-borne Viral Disease group at the Pirbright Institute. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Impact | The genome browser allows the researchers to meaningfully mine and integrate the large amount of data produced by their experiments, guiding subsequent experimental hypothesis-driven validation in the lab. |
| Title | Viral assembly pipeline |
| Description | The Integrative Biology and Bioinformatics group has developed a data analysis pipeline to obtain sensitive and robust viral assemblies out of high-throughput sequencing data. In spite of the relatively short genomic length of most viruses, assembling of viral sequences can be challenging due to several reasons, such as: low amount of material in the sample, which might require amplification, introducing biases, and/or generates low-quality sequences; uneven coverage due to low-quality material or the genomic material of the virus being RNA; the viral nucleic acid being almost lost in the background of nucleic acid of the host. Our pipeline overcomes most of those problems, and is even able to detect different viral strains being present together in the same sample. It can also be used on metagenomic environmental samples. |
| Type Of Material | Data analysis technique |
| Year Produced | 2017 |
| Provided To Others? | No |
| Impact | The pipeline is being deployed as the tool of choice for the nascent sequencing facility at Pirbright. It has been used by several groups at Pirbright, and the FMDV World Reference Lab, in order to assemble very different kinds of viruses. |
| Title | Viral variant calling pipeline |
| Description | The Integrative Biology and Bioinformatics group has developed a data analysis pipeline to obtain sensitive and robust variant calling for viral sequences out of high-throughput sequencing data. In spite of the relatively short genomic length of most viruses, calling variant for viral sequences can be challenging due to several reasons, such as: low amount of material in the sample, which might require amplification, introducing biases, and/or generates low-quality sequences; very high genome coverage, which slows down most existing variant callers; the presence of a potentially very high number of different haplotypes for RNA viruses, which is an unusual scenario in variant calling. Our fast and sensitive Bayesian pipeline overcomes most of those problems. |
| Type Of Material | Data analysis technique |
| Year Produced | 2017 |
| Provided To Others? | No |
| Impact | The pipeline is being deployed as the tool of choice for the nascent sequencing facility at Pirbright. It has been used by several groups at Pirbright, and the FMDV World Reference Lab, in order to assemble very different kinds of viruses. |
| Description | Alain Kohl, Joseph Hughes and Quan Gu, CVR Glasgow |
| Organisation | University of Glasgow |
| Department | MRC - University of Glasgow Centre for Virus Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The aim of this collaboration is to generate reference transcriptomes for two mosquito species of veterinary and human health importance. We generated samples and sequencing data. We also analysed transcriptome data. |
| Collaborator Contribution | Alain Kohl generated samples. Joseph Hughes and Quan Gu generated reference transcriptomes and helped with data analysis. |
| Impact | Outcomes of this collaborations have been poster presentations at national and international conferences. This collaboration is multi-disciplinary as it involves virologists and bioinformaticians. |
| Start Year | 2016 |
| Description | Andres |
| Organisation | University of Tartu |
| Department | Institute of Technology |
| Country | Estonia |
| Sector | Academic/University |
| PI Contribution | We provide mosquito expertise; partner is world-leading arbovirologist, with particular expertise in arboviruses. Obtained joint funding from Wellcome Trust and, separately, DARPA. |
| Collaborator Contribution | Partner is world-leading arbovirologist, with particular expertise in arboviruses. Has provided expertise and materials over several projects and years. |
| Impact | Multiple papers reported separately. Obtained major grants from Wellcome Trust and DARPA. Developed and tested tools for coronavirus reverse genetics, applying our joint expertise to that new problem. |
| Start Year | 2015 |
| Description | Anopheles reannotation |
| Organisation | Centre for Genomic Regulation (CRG) |
| Country | Spain |
| Sector | Academic/University |
| PI Contribution | Provided RNA-sequencing data (produced by Jaroslaw Krzywinski and analysed by us) |
| Collaborator Contribution | Using the data to produce a reannotation of Anopheles Gambiae |
| Impact | No outputs yet |
| Start Year | 2017 |
| Description | Arbovirus reverse genetics systems (AM) |
| Organisation | University of Tartu |
| Country | Estonia |
| Sector | Academic/University |
| PI Contribution | We brought our expertise in flaviviruses, in particular emerging flaviviruses including Zika virus and Alkhumra haemorrhagic fever virus. We also brought our expertise in high containtment virology up to ACDP Hazard Group 3, SAPO3 and Schedule 5 for molecularly characterising recombinant viruses. |
| Collaborator Contribution | The partner brought their expertise in making viral reverse genetics systems for dissecting the function of viral proteins. |
| Impact | A number of reverse genetics systems for flaviviruses have been generated, which are allowing us to interrogate questions about how viruses jump between host and vector species. |
| Start Year | 2018 |
| Description | BBSRC-UC Davis workshop, 16-18 October |
| Organisation | University of California, Davis |
| Department | UC Davis College of Biological Sciences |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Presented on "Reproducibility and relevance in vector infection studies". Followed up with discussion of potential publication and funding opportunities. |
| Collaborator Contribution | Various presentations on vectors and vector-borne diseases including, facilities, challenges, opportunities. |
| Impact | Discussion of potential joint publications and grant applications; no tangible impacts yet. |
| Start Year | 2017 |
| Description | BBSRC-UC Davis workshop, 16-18 October |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Presented on "Reproducibility and relevance in vector infection studies". Followed up with discussion of potential publication and funding opportunities. |
| Collaborator Contribution | Various presentations on vectors and vector-borne diseases including, facilities, challenges, opportunities. |
| Impact | Discussion of potential joint publications and grant applications; no tangible impacts yet. |
| Start Year | 2017 |
| Description | CVR |
| Organisation | University of Glasgow |
| Department | MRC - University of Glasgow Centre for Virus Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Pirbright has several groups investigating various aspects of vector-borne diseases. My group provides mosquito expertise, including gene editing, genetics and transgenesis. CVR have expert arbovirologists with complementary interests. We have developed and exchanged research materials and reagents, shared expertise, and have shared grant funding. |
| Collaborator Contribution | Pirbright has several groups investigating various aspects of vector-borne diseases. My group provides mosquito expertise, including gene editing, genetics and transgenesis. CVR have expert arbovirologists with complementary interests. We have developed and exchanged research materials and reagents, shared expertise, and have shared grant funding. |
| Impact | Joint grant. Several ongoing research strands within this. |
| Start Year | 2021 |
| Description | CVR-TPI collaboration on Rift Valley fever virus and arboviruses |
| Organisation | University of Glasgow |
| Department | MRC - University of Glasgow Centre for Virus Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Provided technical expertise, identified objectives, shared protocols, undertook project and time management, established collaborations with third parties, provided leadership. |
| Collaborator Contribution | The collaborators provided technical expertise and reagents. |
| Impact | Generation of a Rift Valley fever virus reverse genetics system for use in research and commercialization. The RG system enhanced our preparedness to bunyavirus emergence in the UK and Europe more broadly. Over the years, we have published several research articles on arbovirus-insect interactions. We have a joint PhD studentship that commenced in October 2022. |
| Start Year | 2018 |
| Description | Collaboration with Universite Claude Bernard Lyon 1 on bunyavirus-host interactions |
| Organisation | Claude Bernard University Lyon 1 (UCBL) |
| Country | France |
| Sector | Academic/University |
| PI Contribution | We undertake research studies on bunyavirus-host interactions. |
| Collaborator Contribution | Our partners undertake research studies on bunyavirus-host interactions and provide reagents to us. |
| Impact | Exchange of technologies and reagents. |
| Start Year | 2022 |
| Description | Collaborative doctoral project on viral and insect factors influencing BTV replication in Culicoides vector insects |
| Organisation | Friedrich Loeffler Institute |
| Department | Institute of Infectology |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | This is a shared doctoral project funded by the German partner where the student has spend significant time in our lab from August 2019- November 2020. The student has carried out her first initial part of the project (16 months) at FLI in Germany and during this time came for a 2 weeks visit in 2018 to our lab where we provided training on Culicoides biting midge biology, virus titration and handling, virus infection of insects and molecular diagnostics. During her time in our lab she managed to complete all planned insect vector BTV infection studies and generated some interesting results which will be published in the near future. The student returned to FLI for 01.12.2020 and will now complete writing her thesis for a DVM while we jointly work towards publishing of obtained results. |
| Collaborator Contribution | The main project (student salary, some consumables, travel) is funded by the German partner while we contribute costs to the consumable budget for the work carried out in our lab. We will share data obtained at either side and publish results together accordingly |
| Impact | This partnership is still ongoing. Each partner contributes their unique expertise (Virology, insect biology, next-generation sequencing and bioinformatics), the student carried out her placement at The Pirbright Institute from August 2019 to November 2020 |
| Start Year | 2017 |
| Description | Collaborative project on identification of volatile organic chemicals in the body odour of sheep and cattle following bluetongue virus infection |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Expertise in bluetongue virus infection of cattle and sheep and in-vivo animal infection studies plus Virology, Immunology and Entomology expertise especially for Culicoides -borne viruses, exploration of diagnostic methodologies to detect viral infections |
| Collaborator Contribution | Expertise in chemical ecology, identification of volatile organic chemicals released in the body odour of mammals, exploration of diagnostic application of VOC changes in response to infections |
| Impact | Successful application for external funding, project has now started as a collaborative BBSRC grant in 2021. This collaboration combines key disciplines of virology, veterinary medicine with chemical ecology and engineering. |
| Start Year | 2020 |
| Description | Components of the Medea gene drive system in a mosquito Aedes aegypti |
| Organisation | National Health Research Institutes (NHRI) Taiwan |
| Department | Institute of Molecular and Genomic Medicine |
| Country | Taiwan, Province of China |
| Sector | Charity/Non Profit |
| PI Contribution | Developed joined research project and lead successful application for funding |
| Collaborator Contribution | Various lines of research, including construction of plasmids and development and characterisation of transgenic mosquito strains; and group discussions about results, conclusions and research progress. |
| Impact | No impact yet. |
| Start Year | 2018 |
| Description | Components of the Medea gene drive system in a mosquito Aedes aegypti |
| Organisation | National Institute of Genetics |
| Department | NIG-FLY, Mishima (Drosophila RNAi resources) |
| Country | Japan |
| Sector | Academic/University |
| PI Contribution | Developed joined research project and lead successful application for funding |
| Collaborator Contribution | Various lines of research, including construction of plasmids and development and characterisation of transgenic mosquito strains; and group discussions about results, conclusions and research progress. |
| Impact | No impact yet. |
| Start Year | 2018 |
| Description | Engineering mosquitoes for reduced vector competence for chikungunya virus |
| Organisation | University of Malaya |
| Department | Department of Medical Microbiology |
| Country | Malaysia |
| Sector | Academic/University |
| PI Contribution | Developed joint research programme, led successful application for funding, coordinate programme. |
| Collaborator Contribution | Various specific strands of research, and group discussions about results, conclusions, research progress and future activities. |
| Impact | reported under funding |
| Start Year | 2016 |
| Description | Engineering mosquitoes for reduced vector competence for chikungunya virus |
| Organisation | University of Melbourne |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Developed joint research programme, led successful application for funding, coordinate programme. |
| Collaborator Contribution | Various specific strands of research, and group discussions about results, conclusions, research progress and future activities. |
| Impact | reported under funding |
| Start Year | 2016 |
| Description | Engineering mosquitoes for reduced vector competence for chikungunya virus |
| Organisation | University of Tartu |
| Department | Institute of Technology |
| Country | Estonia |
| Sector | Academic/University |
| PI Contribution | Developed joint research programme, led successful application for funding, coordinate programme. |
| Collaborator Contribution | Various specific strands of research, and group discussions about results, conclusions, research progress and future activities. |
| Impact | reported under funding |
| Start Year | 2016 |
| Description | Exploiting mosquito immunity for generating refractory mosquitoes |
| Organisation | The Pirbright Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | I brought my expertise in mosquito immunology and viral evasion of innate immune responses in vertebrates and invertebrates. I provided intellectual input into the project and provided training for three research assistants and one undergraduate placement student. |
| Collaborator Contribution | The partner (Luke Alphey, The Pirbright Institute) brought their expertise in mosquito transgenesis and molecular approaches to developing refractory mosquitoes that cannot transmit viruses. The partner also provided intellectual input into the project. |
| Impact | The following publications are associated with this collaboration: DOI: 10.3390/v13112116 |
| Start Year | 2020 |
| Description | ILRI Research Collaboration (Kenya, March 2017) |
| Organisation | International Livestock Research Institute (ILRI) |
| Country | Kenya |
| Sector | Charity/Non Profit |
| PI Contribution | Exchange of ideas and samples for indigenous breeds of livestock |
| Collaborator Contribution | Contributed samples for analysis. |
| Impact | Analysis of indigenous breed genomic sequences for Immune function genes. |
| Start Year | 2017 |
| Description | Linking sex determination and dosage compensation in a mosquito Anopheles gambiae |
| Organisation | University of Zurich |
| Department | Institute of Molecular Life Sciences |
| Country | Switzerland |
| Sector | Academic/University |
| PI Contribution | Developed a new research program. |
| Collaborator Contribution | Provided intellectual input, contributed to drafting a joined grant proposal. |
| Impact | No output yet. |
| Start Year | 2019 |
| Description | Microbial products in insect saliva and effects on virus infection enhancement |
| Organisation | Boston University School of Medicine |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Sharing of results on the discovery of bacterial LPS in Culicoides saliva and its infection enhancing effect on BTV in bovine monocytes. Discussion of future work and comparison of the results to other insect transmitted viruses including those of high importance to humans |
| Collaborator Contribution | Sharing of data from their portfolio on mosquito saliva effects on virus infectivity and replication. Comparison of methodology and discussion of future collaborations |
| Impact | On-going sharing of results and discussion of future experiments - collaborator left academia to work in industry. Contact still remains. |
| Start Year | 2018 |
| Description | Outreach Network for Gene Drive Research |
| Organisation | Outreach Network for Gene Drive Research |
| Sector | Charity/Non Profit |
| PI Contribution | Input to policy discussions |
| Collaborator Contribution | Network is engaged in briefing national and international entities, e.g. EU/EC, European Parliament, IUCN, Convention on Biological Diversity, on issues related to gene drive. Outreach also relates to general public (directly and via media) as well as policymakers, regulators and practitioners. The Pirbright Institute is now a member of the Network |
| Impact | Briefing and media comment regarding gene drives and gene drive research to multiple agencies e.g. EU/EC, European Parliament, IUCN, Convention on Biological Diversity, on issues related to gene drive. |
| Start Year | 2019 |
| Description | Reannotation of the Anopheles gambiae genome |
| Organisation | Biomathematics and Statistics Scotland (BioSS) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Generated and provided RNA-seq data from the developmental transcriptome of the mosquito Anopheles gambiae Manually browsed the transcriptomic data in the genome context and provided coordinates for genome regions with not annotated genes or genes requiring annotation corrections. Generated and provided FAIRE-seq data from embryo samples of Anopheles gambiae to identify regulatory elements controlling early embryo development. |
| Collaborator Contribution | Conducting reannotation of the Anopheles gambiae genome based on RNA-seq data from the developmental transcriptome. Mapping the FAIRE-seq data to the genome and linking the mapped data the RNA-seq data. |
| Impact | No outputs yet |
| Start Year | 2017 |
| Description | Reannotation of the Anopheles gambiae genome |
| Organisation | Centre for Genomic Regulation (CRG) |
| Country | Spain |
| Sector | Academic/University |
| PI Contribution | Generated and provided RNA-seq data from the developmental transcriptome of the mosquito Anopheles gambiae Manually browsed the transcriptomic data in the genome context and provided coordinates for genome regions with not annotated genes or genes requiring annotation corrections. Generated and provided FAIRE-seq data from embryo samples of Anopheles gambiae to identify regulatory elements controlling early embryo development. |
| Collaborator Contribution | Conducting reannotation of the Anopheles gambiae genome based on RNA-seq data from the developmental transcriptome. Mapping the FAIRE-seq data to the genome and linking the mapped data the RNA-seq data. |
| Impact | No outputs yet |
| Start Year | 2017 |
| Description | Reannotation of the Anopheles gambiae genome |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Generated and provided RNA-seq data from the developmental transcriptome of the mosquito Anopheles gambiae Manually browsed the transcriptomic data in the genome context and provided coordinates for genome regions with not annotated genes or genes requiring annotation corrections. Generated and provided FAIRE-seq data from embryo samples of Anopheles gambiae to identify regulatory elements controlling early embryo development. |
| Collaborator Contribution | Conducting reannotation of the Anopheles gambiae genome based on RNA-seq data from the developmental transcriptome. Mapping the FAIRE-seq data to the genome and linking the mapped data the RNA-seq data. |
| Impact | No outputs yet |
| Start Year | 2017 |
| Description | Role of Ago2 in mosquito antiviral RNAi |
| Organisation | Bernhard Nocht Institute for Tropical Medicine |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | I provided my expertise in generating CRISPR knockout cell lines in mosquito cells and shared these reagents with the collaborators. |
| Collaborator Contribution | The collaborators brought their expertise in RNAi antiviral immunity in mosquitoes. They also brought their intellectual input and trained their own staff on the project. |
| Impact | The following publications are associated with this research: DOI: 10.3390/v13061066 |
| Start Year | 2018 |
| Description | Role of Ago2 in mosquito antiviral RNAi |
| Organisation | University of Glasgow |
| Department | MRC - University of Glasgow Centre for Virus Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | I provided my expertise in generating CRISPR knockout cell lines in mosquito cells and shared these reagents with the collaborators. |
| Collaborator Contribution | The collaborators brought their expertise in RNAi antiviral immunity in mosquitoes. They also brought their intellectual input and trained their own staff on the project. |
| Impact | The following publications are associated with this research: DOI: 10.3390/v13061066 |
| Start Year | 2018 |
| Description | Semiochemical-based detection of arboviral infection |
| Organisation | London School of Hygiene and Tropical Medicine (LSHTM) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Preliminary data collection on the influence of arboviral infection on semiochemical output from sheep. These studies are being conducted as part of an unrelated animal experiment within the isolation units at Pirbright. We are carrying out the animal-based studies and collecting air entrainments from animals both pre- and post-infection. These are then decontaminated for movement to LSHTM. |
| Collaborator Contribution | LSHTM are carrying out analysis of air entrainments using GC-MS. They will assess differences in profiles of infected vs uninfected animals and report their findings to us. |
| Impact | Still ongoing. |
| Start Year | 2018 |
| Description | Semliki Forest |
| Organisation | The Pirbright Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Generated and analysed RNA-sequencing samples with bespoke in-house methods |
| Collaborator Contribution | Generated samples |
| Impact | The purpose of the collaboration is to study how arboviruses interact with their host cells with modern high-throughput techniques. No outputs yet |
| Start Year | 2017 |
| Description | Syngenta UK |
| Organisation | Syngenta International AG |
| Department | Syngenta Ltd (Bracknell) |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | This collaboration aims to identify functional relationships between insecticide resistances in mosquitoes and competence of vector mosquitoes for arboviruses. Further, this collaboration aims at the generation of transgenic mosquitoes overexpressing proteins involved in certain insecticide resistances as tools to study the mechanism for such resistances. We have selected candidate proteins and overexpressed them in cell culture and in mosquitoes for vector competence studies as well as functional studies (insecticide uptake bioassays). |
| Collaborator Contribution | Syngenta UK has provided intellectual input into our study design and expertise in the field of insecticide resistance mechanisms. |
| Impact | No outputs yet. Collaboration between The Pirbright Institute and agrochemical industry. |
| Start Year | 2019 |
| Description | Y chromosome-linked X-shredding gene drives |
| Organisation | Hebrew University of Jerusalem |
| Country | Israel |
| Sector | Academic/University |
| PI Contribution | We shared with the partner Y chromosome-linked docking lines generated in our lab. |
| Collaborator Contribution | Provided some plasmid constructs. |
| Impact | No outputs yet. |
| Start Year | 2021 |
| Description | 1st Research Coordination Meeting (RCM) of the Coordinated Research Project (CRP) on "Generic approach for the development of genetic sexing strains for SIT applications" Vienna, 7-11 October 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | FAO/IAEA Coordinated Research Project on exploring genetic and molecular methods of sex separation in insect pests; aimed at promoting specific areas of research, exchange of ideas and networking among the experts in the field. |
| Year(s) Of Engagement Activity | 2019 |
| Description | 2019 Culture of Care Meeting Pirbright |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The fourth annual Culture of Care and 3Rs meeting was hosted at The Pirbright Institute on 16 October 2019. Dr Beatriz Sanz-Bernardo presented the advancements made in applying the 3Rs to lumpy skin disease research. These include refining biopsy procedures to minimise animal suffering and replacing laboratory experiments with simulations modelling host-vector interactions. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.pirbright.ac.uk/news/2019/10/pirbright%E2%80%99s-2019-culture-care-meeting-focuses-anima... |
| Description | 360 degree Lab Animal Tour (and film) of The Plowright Building, The Philip Mellor Insectary, and Animal Isolation Facilities |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | The website provides unique access to the animal research facilities at The Pirbright Institute which support its world-leading scientific research into livestock viral diseases and helps save countless animal and potentially human lives, globally. Produced and filmed by Understanding Animal Research, the Lab Animal Tour was filmed at Pirbright, and at three other research centres, and provides the viewer with an interactive 360 virtual tour of the animal facilities. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.labanimaltour.org/pirbright |
| Description | AB Improving Approaches to Prevent and Control Viral Diseases of Livestock and Poultry |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Batra, A., Maier, H.J., Britton P., Hiscox, J.A., Fife, M.S., 2015. PI3K/AKT signalling during infectious bronchitis virus infection. Food Security: Improving Approaches to Prevent and Control Viral Diseases of Livestock and Poultry, British Council Research Links Workshop, Istanbul, Turkey (Oral presentation) |
| Year(s) Of Engagement Activity | 2015 |
| Description | AB Society of General Microbiology Annual conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presentation. Batra, A., Maier, H.J., Britton, P., Hiscox, J.A., Fife, M.S. AKT activation during infectious bronchitis virus infection. Society of General Microbiology Annual conference, Liverpool, UK |
| Year(s) Of Engagement Activity | 2013,2014,2015 |
| Description | AHSV talk on transmission for OIE (Thailand online) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk on transmission of AHSV to interested parties following outbreak in 2020. Talk given on 9/6/20 to approx 150. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Amy Lewis, The Scientist, 15/08/2017 re gene drive and Predator Free NZ 2050 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Provided information and quotes for article on potential use of gene drives as part of New Zealand effort to eradicate invasive predators |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.the-scientist.com/?articles.view/articleNo/50180/title/Driving-Down-Pests/ |
| Description | Ash Manor GCSE Mentoring 2018 - BA |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | BBC Today programme 24/01/2019 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Interview on BBC Today programme regarding potential development and use of gene drives in mice |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.bbc.co.uk/sounds/play/m00025bt |
| Description | BBSRC COP Climate Change Bites 21/05/2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | BBSRC-sponsored event "Climate Change Bites" - talks and panel discussion about the effects of climate change on vector-borne disease |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://bbsrc.ukri.org/news/events/2021/climate-change-events/ |
| Description | BBSRC website article: Halloween |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Article on BBSRC website: Halloween Creepy Crawlies |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.bbsrc.ac.uk/news/fundamental-bioscience/2017/171031-f-uk-creepiest-creepy-crawlies/ |
| Description | BIotech YES 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Gave a talk at the BBSRC Biotechnology Young Entrepreneurs' Scheme event at Syngenta (Jealott's Hill) |
| Year(s) Of Engagement Activity | 2019 |
| Description | Big Bang Fair South East - RC |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Regional science festival/event - changes in public attitudes and stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Biotech YES, Syngenta Jealott's Hill, 05 Oct 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Teams of postgraduate students from a number of universities and institutes attended talk as part of Biotech YES (Young Entrepreneurs' Scheme). Follow-up discussion influenced several aspects of their approach to entrepreneurship both within the competition and more generally |
| Year(s) Of Engagement Activity | 2014,2015,2016,2017 |
| Description | Bluetongue and Wildlife (15 minute presentation on Epizootic Haemorhagic Disease Virus), (July/Pirbright, UK) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Policymakers reported greater interest in deer-associated diseases including EHDV and BTV |
| Year(s) Of Engagement Activity | 2018 |
| Description | Bluetongue in wildlife workshop - presentation on "Bluetongue virus in deer (and other wildlife) - pathogenesis and immune responses" July 2018 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Policymakers/politicians |
| Results and Impact | This workshop brought together policy makers, veterinary advisers and scientist to share information and discuss the role of wildlife for important Culicoides-borne viruses of ruminants. Gave 15 minutes presentation on "Bluetongue virus in deer (and other wildlife) - pathogenesis and immune responses" |
| Year(s) Of Engagement Activity | 2018 |
| Description | Briefing - EU/Estonia parliamentarians and policy advisers |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Briefed Estonian delegation to Brussels/EU parliament on gene drives and related issues |
| Year(s) Of Engagement Activity | 2020 |
| Description | CBD Open-ended online forum on synbio 06-10/2017 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | UN Convention on Biodiversity. Policy- discussion on synthetic biology: nominated participant in the Open Ended Online Forum on Synthetic biology as established in decision XII/24 of the Conference of the Parties to the Convention on Biological Diversity (COP) and extended in COP decision XIII/17 which ran from June to Oct 2017 (approx.) |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://bch.cbd.int/synbio/open-ended/discussion/ |
| Description | CBS briefing 26/05/2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Briefed CBS journalist in relation to story about release of transgenic mosquitoes in Florida |
| Year(s) Of Engagement Activity | 2021 |
| Description | CNN interview |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Interview with CNN journalist. Journalist later followed up asking me to check and clarify some issues. |
| Year(s) Of Engagement Activity | 2019 |
| Description | CT Engagement Talk |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Gave a presentation on mosquito vectors of infectious diseases and novel GM control methods to sixth form biology students (45 minutes). |
| Year(s) Of Engagement Activity | 2021 |
| Description | Cafe Scientifique, Bradfield School, West Berkshire: "How insects spread viruses" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Cafe Scientifique is a public forum for exploring the latest ideas in science and technology. Meetings take place in cafes, bars, restaurants and even theatres, but always outside a traditional academic context. I presented to an audience of the general public and answered questions. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Cafe Scientifique, Reading: "How insects spread viruses" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Cafe Scientifique is a public forum for exploring the latest ideas in science and technology. Meetings take place in cafes, bars, restaurants and even theatres, but always outside a traditional academic context. I presented to an audience of the general public and answered questions. |
| Year(s) Of Engagement Activity | 2007,2017 |
| Description | Camberley Library Fun Palace 2018 - JM |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Changes in public attitudes and stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Caroline Seydel Genetic Literacy Project re GM mosquitoes/gene drive/Zika |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Provided background material and quotes for article on GM mosquitoes and control of Zika virus. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://geneticliteracyproject.org/2018/01/29/waging-war-mosquito-split-gene-drive-hinder-spread-zik... |
| Description | Chair and Co-Organiser for UK Vector-borne Diseases Conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | UK Vector-borne Diseases meeting held bi-Annually. Half day sessions on 2nd, 9th, 16th, 23rd November 2020. Chaired session on 9th November 2020. Meeting was held online with invited and selected presentations and a poster session. Also included funders from Defra and BBSRC. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Chair of organising Committee for Wellcome Trust-Animal Genetics and Diseases 2017 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | This meeting brought together specialists working on the interface between genomics, genetic engineering and infectious disease with the aims of improving animal and human health and welfare. Scientific sessions included: Genetics of immune responses and disease resistance Genetically engineered livestock (including genome editing) Quantitative genetics and epigenetics applied to disease Epidemiology and pathogen evolution Bioinformatics, comparative and functional genomics Precision medicine of animal companions |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://coursesandconferences.wellcomegenomecampus.org/events/item.aspx?e=635&dm_i=2SUU,HOGH,4R4AW1,... |
| Description | Cheltenham Science Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Institute stand at the festival covering the Institute science in general, and transmission and gene editing to control disease, in particular. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Cheltenham Science Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Stimulating increased interest in science and research |
| Year(s) Of Engagement Activity | 2019 |
| Description | Cheltenham Science Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Increasing interest in science and research |
| Year(s) Of Engagement Activity | 2019 |
| Description | Cheltenham Science Festival 2018 - JA |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Major science festival - changes in public attitudes and stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Cheltenham Science Festival 2018 - JM |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Major science festival - changes in public attitudes and stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Cheltenham Science Festival 2018 - JP |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Major national science festival - changes in public attitudes and stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Cheltenham Science Festival 2018 - RC |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Major science festival - changes in public attitudes and stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Cheltenham Science Festival 2018 - SV |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Display at major science festival: changes in public attitudes and stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Cheltenham Science Festival 2018-DP |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Major national science festival - changes in public attitudes and stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Commentary on AHSV outbreak in Thailand in Science Magazine |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | 'Thailand scrambles to contain major outbreak of horse-killing virus' - Article in Science Mag April 2020 |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.sciencemag.org/news/2020/04/thailand-scrambles-contain-major-outbreak-horse-killing-viru... |
| Description | DB Winston Churchill School Careers event |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | School careers event for a Secondary School - 1500 children ages 11 to 16 years |
| Year(s) Of Engagement Activity | 2021 |
| Description | Diego Friere Pesquisa Fapesp |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Interview with journalist leading to article regarding release of transgenic mosquitoes into the environment to control dengue and other diseases |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://revistapesquisa.fapesp.br/en/2020/02/05/jacobina-controversy/ |
| Description | Discuss gene drives with NZ Parliamentary Commissioner |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Met NZ Parliamentary Commissioner to provide background information on, and discuss, gene drive systems. New Zealand is considering genetic and other control methods for invasive pests. |
| Year(s) Of Engagement Activity | 2018 |
| Description | EFSA Hearing Expert Gene Drive Environmental Risk Assessment Working Group |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Hearing Expert for EFSA Gene Drive Environmental Risk Assessment Working Group. Contributed to EFSA Scientific Opinion. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2020.6297 |
| Description | EFSA consultation July 2020 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Responded to European Food Standards Authority (EFSA) request for input regarding regulation of gene drives (public consultation) |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/sp.efsa.2020.EN-1939 |
| Description | EMBO Conference: Molecular and population biology of mosquitoes and other disease vectors: vector and disease control |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation on "Manipulation of the sex determination pathway in the African malaria mosquito Anopheles gambiae" given during the meeting held on 24 - 28 July 2017 in Kolymbari, Greece. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://meetings.embo.org/event/17-vector-control |
| Description | EMBO Workshop: Molecular and population biology of mosquitoes and other disease vectors: vector and disease control |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation on "Sex determination pathway in Anopheles gambiae as a target for mosquito control" given during the meeting held on 22 - 26 July 2019 in Kolymbari, Greece. Following a presentation a request was made to give an informal seminar at the Department of Life Sciences, Imperial College, London. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://meetings.embo.org/event/19-mosquitoes |
| Description | EPO Inventors Revisited video |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Podcast for European Patent Office "Inventors Revisited" series |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.epo.org/news-events/events/european-inventor/inventors-revisited.html |
| Description | EPO TalkInnovation Facebook live event and podcast |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | EPO TalkInnovation Facebook live event and podcast discussing use of genetic methods to control mosquitoes and mosquito-borne disease |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.facebook.com/europeanpatentoffice/videos/a-minute-change-that-makes-a-massive-difference... |
| Description | ESA Vancouver |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Research talk to Entomological Society of America conference. 2000+ attendees and 200+ in session. Resulted in dfurther disscussions with aim to develop international collaborations. |
| Year(s) Of Engagement Activity | 2018 |
| Description | ESA presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at Entomological Society of America, concerning overwintering mechanisms and vector competence of Culicoides biting midges as vectors of bluetongue virus. |
| Year(s) Of Engagement Activity | 2022 |
| Description | EU parliament webinar |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Invited speaker for European Parliament Intergroup on Climate Change, Biodiversity and Sustainable Development webinar "Research and Innovation for biodiversity: what role for gene drive research?" |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://ebcd.org/event/online-event-research-and-innovation-for-biodiversity-what-role-for-gene-driv... |
| Description | Edinburgh Science Festival |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Talk and panel event at Edinburgh Science Festival "The Buzz about GM Insects". Sparked questions and discussions afterwards including some career questions. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Edinburgh seminar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Gave invited seminar at Edinburgh University (via Zoom) regarding development and applications of transgenic mosquitoes. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Encouraging women into science and engineering STEM. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | MH Visited Warwick School, Redhill to talk to secondary students about careers in STEM. A very positive outcome and well received. |
| Year(s) Of Engagement Activity | 2018 |
| Description | EpiRisk Workshop, IZS Teramo, Italy |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation on work done as part of EFSA lumpy skin disease working groups to inform risk modellers/epidemiologists about possible approaches |
| Year(s) Of Engagement Activity | 2019 |
| Description | Epizone, Berlin - invited speaker |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Invited speaker on "Orbiviruses on the move" at the EPIZONE conference in Berlin 2019, audience mixture of veterinary virologists, early career researchers and veterinary policy makers |
| Year(s) Of Engagement Activity | 2019 |
| Description | Established a Twitter account for the Orbivirus research group |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Established group Twitter account in August 2019 to advocate our work and wider scientific themes of interest, continuous increase of followers |
| Year(s) Of Engagement Activity | 2019 |
| Description | European Society Vector Ecology (Invited Chair for two sessions and speaker for 15min talk); (October/Palermo, Sicily) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chaired two sessions, one on vector-borne diseases, one on scientific networks. Latter included a discussion with early career researchers. Main outcome was coordination between active networks including The Gnatwork. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.sove.org/European%20SOVE%20folder/greecescientificprogram/palermo_Scientific_program_revi... |
| Description | Ewen Callaway Nature 08/01/2018 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Provided expert background information for article in Nature regarding engineering species barriers, described by journalist as "very helpful" in followup email. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Expert commentary on New Scientist article |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | I provided expert commentary on an article published in New Scientist, which summarised research performed by researchers at the University of Leeds on how mosquito bites enhance the transmission of vector-borne diseases. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://institutions.newscientist.com/article/2231141-skin-cream-applied-to-mosquito-bites-stops-vir... |
| Description | FAO/IAEA Coordinated Research Programme on methods of sex separation in mosquitoes; Research coordination meeting Bangkok 19-23 February 2018 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | FAO/IAEA Coordinated Research Programme on exploring genetic, molecular, mechanical, and behavioral methods of sex separation in mosquitoes; aimed at promoting specific areas of research, exchange of ideas and networking among the experts in the field. |
| Year(s) Of Engagement Activity | 2013,2015,2016,2018 |
| Description | Facebook Live: Infectious Disease Portrayals in Pop Culture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Infectious diseases are a frequent topic in movies. The CDC has used zombies to talk about infectious disease and disaster preparedness, and infotainment has flamed fears of Ebola. I took part in a Facebook Live chat organised by the AAAS Public Engagement team about why infectious diseases are so often the topic of pop culture discussions; what movies, books, and other pop culture gets right and wrong about infectious disease; and how scientists can use pop culture as a jumping-off point for public engagement. The chat was broadcast live on the AAAS Facebook page. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.aaas.org/event/facebook-live-infectious-disease-portrayals-pop-culture |
| Description | Fleet Brownies |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Increasing interest in women for science and research |
| Year(s) Of Engagement Activity | 2019 |
| Description | Gene Drive Resarch Sponsors and Supporter's Forum meeting Montreal Sept 2018 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | Forum met to discuss the state of the art and future considerations for gene drive research. Ongoing deliberations including specific follow-up meetings. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Green Thinking COP 26 BBC Podcast |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Podcast discussion of impact of climate change on vector-borne diseases, with regard to COP26. Short interview and discussion. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.bbc.co.uk/programmes/p09y41d0 |
| Description | Holly Kernot, Veterinary Times, 13/06/2017 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Discussed potential of manipulating mosquito sex determination genes as tools for novel mosquito genetic control approaches. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.vettimes.co.uk/news/study-to-be-transformational-in-mosquito-control-strategies/ |
| Description | Holt School Surrey. Bee meadow & A-level outreach Talk. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | I discussed the importance of pollinators for biodiversity and food security with the younger students. I also discussed careers in science with A-Level students. There was good interaction and many questions surrounding both topics. |
| Year(s) Of Engagement Activity | 2018 |
| Description | IUCN Technical Subgroup on Synthetic Biology and Biodiversity Conservation (meeting 12-15 April and report) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Participated as member in Technical Subgroup on Synthetic Biology and Biodiversity Conservation of International Union for Conservation of Nature (IUCN). Meetings, online discussion and ultimately a report to Task Force and will ultimately go to IUCN General Assembly. |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | InnovSur : Conference in IRD Montpellier on Insect Vector Surveillance |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Working group on standardisation of techniques for surveillance of insect vectors. Included break out group brainstorming and subsequent commentaries. Total audience approximately 110 people for main lectures. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.alphavisa.com/isessah-innovsur/2018/ |
| Description | Innovate Guildford 17 March 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Talk and exhibit at Innovate Guildford - >100 for talk, probably >500 for exhibit. Both sparked questions and discussion afterwards. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Innovate Guildford 2018 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Institute stand at the Innovate Guildford event, covering the work of the Institute in general and genetic modification through gene editing specifically. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.guildford.gov.uk/IG18 |
| Description | Innovate Guildford 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Gave open talk at Innovate Guildford; 50-60 audience with wide age range, many questions and lively debate |
| Year(s) Of Engagement Activity | 2018 |
| Description | Innovate Guildford 2018 - JM |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Regional science/innovation event - changes in public attitudes and stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Innovate Guildford 2018 - SB |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Regional science festival - changes in public attitudes and stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Innovate Guildford 2018 - SV |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Display at regional science/innovation festival - changes in public attitudes and stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Innovate Guildford Outreach (12th March) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | With amazing exhibits, activities, workshops, talks and competitions, it's FREE to attend. Explore the four zones: Engineering, One Health, Digital Media and Future Living, experience interactive performances, hear inspiring speakers (including leading gaming pioneer Peter Molyneux and animal health pioneer Professor Nick Bacon) and take in an amazing atmosphere. Theatre, music and comedy will feature through the day, with everything from how technology might have affected Shakespeare's plays to risky recycling and photographic secrets. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.guildford.gov.uk/innovateguildford |
| Description | Insect Festival 2017 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Ran a stand on blood-sucking arthropods and their role in the transmission of disease at the Royal Entomological Society's Insect Festival. Talked to public, answered questions. Lots of enquiries about ticks, midges, mosquitoes and large biting flies (particularly horseflies). |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.yorkmuseumstrust.org.uk/whats-on/events/insect-festival-2017/ |
| Description | Institute stand "Disease Detectives" at Royal Society Summer Science Exhibition |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | Institute stand "Disease Detectives" at Royal Society Summer Science Exhibition, 6-10 July 2022 |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://royalsociety.org/science-events-and-lectures/2022/summer-science-exhibition/ |
| Description | Institute stand at Surrey Vet School open day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Stimulating increased interest in science and research |
| Year(s) Of Engagement Activity | 2019 |
| Description | Interview on "Disease Detectives" |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Interview about "Disease Detectives" for BBC World Service Health Check programme, broadcast 7 July 2022 |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.bbc.co.uk/sounds/play/w3ct32wl |
| Description | Interview on lumpy skin disease |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Interview on lumpy skin disease with Simon Quilty of Global AgriTrends |
| Year(s) Of Engagement Activity | 2023 |
| Description | Interview with book author |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Interview with FT journalist for book |
| Year(s) Of Engagement Activity | 2020 |
| Description | Invited Chair at European Congress of Entomology (Naples,July) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chaired session on vector-borne diseases at meeting and subsequent question sessions with 15 minute presentation on Culicoides biting midges. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.ece2018.com/scientific-programme/day-1-monday-2-july/ |
| Description | Invited Lecture - Antivec Network |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation give on 'The Gnatwork'. 21/06/19. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.gla.ac.uk/research/az/antivec/ |
| Description | Invited Lecture - Public Health Interest Group (London School Hygiene and Tropical Medicine) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited talk presented and discussion session particiation (09/04/19) |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited Lecture - Wageningen University and Research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk title: Culicoides-borne arboviruses in Europe - Invited lecture |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited expert to the International gnatwork training workshop in Bangladesh |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | One of the invited disease experts to deliver an international training workshop in Bangladesh on the biology and vectorial roles of blackflies, sandflies and Culicoides biting midges. Initially this involved a presentation on "Of creatures big and very small - veterinary aspects of veterinary vector-borne pathogen research" at the start-up conference in Dhaka followed by a 4 day practical workshop at the BRAC learning centre (Mymensingh) where I was part of the training team on study design, data analysis and genetic identification of vector insects using molecular diagnostics. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.gnatwork.ac.uk/bangladesh-18 |
| Description | Invited expert to the international Gnatwork training course in Brazil |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | First day gave a presentation on veterinary aspects of vector-borne virus research at the School of Veterinary Medicine Belo Horizonte Brazile, followed by 4 day training workshop were I taught sections on molecular diagnostics applied to insect vectors, poster presentations, scientific writing |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.gnatwork.ac.uk/brazil-19 |
| Description | Invited presentation at the Friedrich Loeffler Institute (January; Riems) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Formal presentation on biting midges and bluetongue to professional audience with question session and collaborative meetings |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited seminar at UC Riverside 05/05/2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited seminar at University of California, Riverside |
| Year(s) Of Engagement Activity | 2017 |
| Description | Invited seminar at the National Health Research Institutes, Taiwan. 27 Feb 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A presentation describing research in my group on mosquito developmental biology and its potential uses for mosquito control; attended by primarily by members of the National Mosquito-Borne Diseases Control Research Center. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited speaker British Society of Veterinary Pathology Annual Meeting 2018, Applied Ruminant Pathology |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited speaker on "Bluetongue virus and Schmallenberg virus - recognising the continued threat of Culicoides-borne viruses of ruminants" British Society of Veterinary Pathology Annual Meeting 2018, Applied Ruminant Pathology School of Veterinary Medicine, University of Surrey, 29th of September 2018, |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.bsvp.org/event/applied-ruminant-pathology-disease-investigation-diagnosis-and-surveillan... |
| Description | Invited speaker VECTOR-BORNE DISEASES (VBD) IN THE UK - BIENNIAL MEETING 2018 John Innes Centre Norwich |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited speaker on "The Host-vector-pathogen Interface of Culicoides-borne Bluetongue Virus" at the VECTOR-BORNE DISEASES (VBD) IN THE UK - BIENNIAL MEETING 2018 John Innes Centre Norwich 4th-5th December 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited speaker at APHA surveillance meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited speaker on insect surveillance at Animal and Plant Health Agency meeting with discussion around current studies. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited to attend and present at the RSPCA Lay members Forum, Royal Society London 10th of December 2018 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Third sector organisations |
| Results and Impact | Invited to attend to the RSPCA Lay members Forum, Royal Society London 10th of December 2018 and present on the ethical review process of animal research |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://science.rspca.org.uk/sciencegroup/researchanimals/ethicalreview/differentsystems/uk/events |
| Description | Invited to give an online seminar for the Western College of Veterinary Medicine University of Saskatchewan |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited by the Western College of Veterinary Medicine University of Saskatchewan to give the external seminar. The title of the presentation was Of creatures big and very, very small - the continuous threat of bluetongue virus to ruminants, which was attended by over 50 staff members and students |
| Year(s) Of Engagement Activity | 2021 |
| Description | Isabelle Dietrich - Bishop David Brown School Careers Fair |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | >100 students attended careers fair. Informed students about The Pirbright Institute's work and career opportunities. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Isabelle Dietrich - Collingwood College Careers Fair |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | >100 students attended careers fair. Informed students about The Pirbright Institute's work and career opportunities. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Isabelle Dietrich - Poster at IMAV 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Conference presentation, followed by questions and discussions and establishment of new collaborations. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Isabelle Dietrich - Talk at "Symposium on New Emerging Mosquito-Borne Diseases and Vectors", Taiwan |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Conference presentation, followed by questions and discussions and establishment of new collaborations. Judged poster competition. Visited collaborators' institutes to introduce The Pirbright Institute's work in general and our group's work in particular. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Isabelle Dietrich - Talk at RIVR |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Conference presentation, followed by questions and discussions. |
| Year(s) Of Engagement Activity | 2020 |
| Description | JN (DB) Ash Manor - vaccines and COVID |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Series of talks presented to pupils at Ash Manor - the talks were focused on vaccines and COVID and the subjects generated lots of discussion and interest. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Kingdown School Warminster Wiltshire talk to 6th form students about career in science. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | I presented my career path to the students to engage them on STEM careers. I had a good level of discussion and many questions. |
| Year(s) Of Engagement Activity | 2018 |
| Description | LSD Epizone 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Oral presentation at 13th annual epizone meeting, Berlin 2019. "Risk of transmission of LSDV from experimentally infected cattle to insect vectors". Beatriz Sanz Bernardo. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Launch of first industry guidance on safe working with arthropods and GM insects |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Around 50 biosafety professionals and regulators including representatives from HSE attended the formal launch of the first industry guidance on working safely with arthropods and genetically modified insects on 21st April at Pirbright. This initiative originated with Sharon Webster, Chair of ISTR's Biosafety Steering Group, and was developed based on consultation with myself and members of my group with practical experience of working with arthropods in containment. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.pirbright.ac.uk/news/2017/04/first-industry-guidance-safe-working-arthropods-and-gm-inse... |
| Description | Lecture given to University of Surrey MSc Veterinary Microbiology students |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | A 2-hour teaching lecture given to 10 MSc Veterinary Microbiology students at the University of Surrey on 8th December (Lara Harrup) |
| Year(s) Of Engagement Activity | 2017 |
| Description | Lecture of dynamics of vector-borne diseases |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Undergraduate students |
| Results and Impact | Two-hour lecture on the dynamics of vector-borne diseases as part of Part II Pathology: Dynamics of Infectious Diseases course at University of Cambridge |
| Year(s) Of Engagement Activity | 2008,2009,2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020,2021,2022,2023,2024 |
| Description | Lecture on dynamics of infectious diseases |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Lecture as part of MSc in Veterinary Microbiology at University of Surrey |
| Year(s) Of Engagement Activity | 2012,2013,2014,2015,2016,2017 |
| Description | MF PAG |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The Plant and Animal Genome XXIV Conference (PAG) is designed to provide a forum on recent developments and future plans for plant and animal genome projects. Consisting of technical presentations, poster sessions, exhibits and workshops, the conference is an excellent opportunity to exchange ideas and applications on this internationally important project. |
| Year(s) Of Engagement Activity | 2014,2016 |
| Description | MRC PhD Student DTP |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | I gave a career development seminar to the MRC PhD student DTP to discuss opportunities and realities of an academic research career in universities and research institutions. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Microbiology Society talk |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Oral presentation at Microbiology Society Annual Conference 2019 |
| Year(s) Of Engagement Activity | 2019 |
| Description | New Scientist interview |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Interview with New Scientist regarding genetic control of mosquitoes |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.newscientist.com/article/2210190-parasite-brings-down-mosquito-numbers-in-parts-of-guang... |
| Description | Nick Rufford, Sunday Time Mag, published 27/08/2017 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Provided information and quotes for Sunday TImes Magazine article on GM mosquitoes and Zika |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.thetimes.co.uk/article/how-genetically-engineered-mosquitoes-will-save-lives-kwc8nmwh5 |
| Description | OIE expert lecture AHSV transmission in Thailand |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Online lecture on AHSV transmission following unprecedented outbreak in Thailand - part of OIE arranged seminar series. 20th April 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://rr-asia.oie.int/en/events/oie-webinar-on-the-african-horse-sickness/ |
| Description | Organiser of the Animal Genetics and Diseases conference 08 - 10 May 2019 Wellcome Genome Campus, UK. Highlighting recent advances in animal genetics and genomic technologies. |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I am on the organising committee for this conference. The second conference in this series will highlight recent advances in animal genetics and genomic technologies. It will bring together specialists working on the interface of genomics, genetic engineering and infectious disease with the aims of improving animal and human health and welfare. Novel genomic technologies, mathematical modelling and quantitative genetics approaches, applied to host animals, as well as their pathogens, have transformed the understanding of animal diseases, host-pathogen interactions and epidemiology and their effects on productivity of farmed animal species and food supply chains. This year's conference will not only put the spotlight on the immune response of host animals and epidemiology but also cover the genetics and genomics of pathogens and the impact of animal-human relationships. We encourage registrations from researchers, breeders and technical specialists interested in learning and disseminating the latest cutting-edge techniques and methodologies across model species, wildlife, farmed animals and companion animals. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://coursesandconferences.wellcomegenomecampus.org/our-events/animal-genetics-diseases-2019/?dm_... |
| Description | Oxford DTP students |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | High level overview of diseases studied [at Pirbright], and the importance of our work, provided to a group of over 30 Oxford DTP students, followed by a networking lunch (29th September 2017). |
| Year(s) Of Engagement Activity | 2017 |
| Description | PP Lumpy Skin Disease OIE and FAO Regional Meeting for Asia and the Pacific |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation on Lumpy Skin Disease OIE and FAO Regional Meeting for Asia and the Pacific. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Pandemic Live (Cheltenham Science Festival) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Approximately 250 attendees at a 1 hour discussion around a simulated virus outbreak scenario (Speakers Fry; Carpenter; Beard; Hatchett). Followed by question and answer session. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.cheltenhamfestivals.com/science/whats-on/2018/pandemic-live/ |
| Description | Participant in IDEAS arboviruses workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Participated in discussions and breakout groups, formed contacts. Planned future meetings on minimum reporting standards in insect infection studies (now funded and scheduled for 2018). |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://ideas.princeton.edu/workshop-for-2017/ |
| Description | Participation in a meeting regarding sex determination, Duesseldorf, Germany |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation entitled "Sex determination pathway in Anopheles gambiae as a target for mosquito control" during the Nothiger meeting on sex determination in insects, Duesseldorf, 11-13 March 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Population Biology of Vector-Borne Diseases Symposium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation on "Population biology of Culicoides-borne viruses in Europe" at symposium held at University of Georgia Athens on 24 February 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Postdocteral scientist - oral presentation at the 12th Annual meeting of Epizone (joint with 11th International Congress for Veterinary Virology, ESVV 2018) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Postdoctoral scientists abstract submission was selected for oral presentation. Project results obtained at the time were presented to a highly interested and engaging audience of more than 250 scientists, veterinarians, students and policymakers. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.epizone-eu.net/en/Home/News/show/Abstract-book-EPIZONEESVV-meeting-now-online-.htm |
| Description | Poster at IMAV 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Poster presentation at IMAV 2019: INTERNATIONAL MEETING ON ARBOVIRUSES AND THEIR VECTORS 05 - 06 September 2019 "Lumpy skin disease virus: transmission to dipteran vectors using animal and ex-vivo models" Beatriz Sanz-Bernardo |
| Year(s) Of Engagement Activity | 2019 |
| Description | Poster presentation at Microbiology Society Annual Conference - Wnt signalling in Rift Valley fever virus infection of mosquito cells |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Conference attendees attended the poster session, which resulted in questions and discussions. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Predicting Pandemics (Panel discussion at Cheltenham Science Festival) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Stimulating increased interest in science and research |
| Year(s) Of Engagement Activity | 2019 |
| Description | Presentation and sicussion with members of the CLA group visiting Pirbright Institute |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | The CLA is the membership organisation for owners of land, property and businesses in rural England and Wales. The CLA came for a visit to the Pirbrigtht Institute and I presented on Bluetongue virus epidemiology, transmission and risk to the UK agriculture followed by a general discussion |
| Year(s) Of Engagement Activity | 2017 |
| Description | Presentation at "Vector-borne disease in the UK" conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation on recent work on the transmission and control of lumpy skin disease |
| Year(s) Of Engagement Activity | 2020 |
| URL | http://www.hpruezi.nihr.ac.uk/media/46429/vbd-2020-programme.pdf |
| Description | Presentation at the EU BTV reference laboratory meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Presentation of BTV pathogenesis and effects of Culicoides saliva to representatives from all European reference laboratories plus some additional participants from the EU and industry |
| Year(s) Of Engagement Activity | 2017 |
| Description | Princess Anne opening Jenner |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Princess Anne, entourage, local politicians and dignitaries visited to open new research building. I was one of small number asked to present/demonstrate/describe our research work, which is on genetic modification of mosquitoes to provide new tools with which to help control mosquito-borne viral diseases. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Provision of educational material on Rift Valley fever virus for Royal Society Summer Festival |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | We prepared information material for an exhibition on Rift Valley fever virus at the Royal Society Summer Festival. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Public Health Entomology Group (LSHTM) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited lecture on 4th April 2017. |
| Year(s) Of Engagement Activity | 2017 |
| Description | RES presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Virus transmission and competence in Culicoides biting midges |
| Year(s) Of Engagement Activity | 2019 |
| Description | RSB Animal Science Group Sept 2018 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Participated in RSB Animal Science special-interest group discussion on development of gene drives. |
| Year(s) Of Engagement Activity | 2018 |
| Description | RSB Genetic Tech Governance Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Workshop hosted by the Royal Society of Biology (RSB) on the use of genetic technologies and the governance and regulation of organisms developed by genetic modification, genome editing and other breeding methods |
| Year(s) Of Engagement Activity | 2019 |
| Description | Reddit AMA (Ask Me Anything) on vector-borne diseases |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Took part in a Reddit Ask Me Anything (AMA) on vector-borne diseases. AMAs are a question-and-answer format activity where an individual expert or panel of experts answers questions from the public for a specified duration. We received a large number of questions and the parent post received 493 upvotes, indicating an absolute minimum of 493 participants (and very probably more), so I have given the estimated audience as 500+. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.reddit.com/r/science/comments/6he8go/aaas_ama_hi_were_maria_elena_bottazzi_marcia/ |
| Description | Representing the Pirbright Institute at the UKRI Festival of Tomorrow in Swindon |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | The Pirbright Institute has a interactive exhibit at The UKRI Festival of tomorrow which the postdocteral scientist on the project attended to represent the overall scientific remit of the Pirbright Institute but also provide specific engagement with project specific research. The attendance and interaction of the expedition and interactive activities was excellent |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.pirbright.ac.uk/news/2022/03/inspiring-generation-%E2%80%93-festival-tomorrow |
| Description | Respond to SMC enquiry re gene drives in mice |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Responded to Science Media Centre request for expert comment on a scientific paper regarding gene drives in mice. Quoted in The Independent |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.independent.co.uk/news/science/gene-editing-dna-technology-mice-pests-drives-invasive-sp... |
| Description | Respond to SMC request re Vosshall paper 08 Feb 2019 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Respond to SMC request re scientific paper describing behaviour-altering drugs in mosquitoes |
| Year(s) Of Engagement Activity | 2019 |
| Description | Respond to request for comment - MIT News |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Interview regarding local "daisy" gene drives in mosquitoes |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://news.mit.edu/2019/daisy-chain-gene-drives-keeping-genetic-engineering-localized-0402 |
| Description | RobinB 25/04/22 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Responded to enquiry from journalist regarding a recent grant, and funding environment generally. Email discussion with follow-up comments and questions |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.researchprofessionalnews.com/rr-news-europe-horizon-2020-2022-4-senior-uk-researchers-co... |
| Description | Royal Institution Christmas Lectures Family Day - LA |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Six Pirbright staff/students ran an all-day exhibit on gene editing and mosquitoes at the Royal Institution About 270 participants visited our stand; wide range of comments, questions, discussion and feedback |
| Year(s) Of Engagement Activity | 2019 |
| Description | Royal Institution Christmas Lectures Family Day - SB |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | About 270 participants visited our stand; wide range of comments, questions, discussion and feedback |
| Year(s) Of Engagement Activity | 2019 |
| Description | Royal Society Summer Exhibition |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Engaged the public on the uses of genetically modified mosquitoes for preventing disease transmission, and on the drivers of viral emergence events at the Royal Society Summer Exhibition (with thousands of attendees). |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://royalsociety.org/science-events-and-lectures/2022/summer-science-exhibition/ |
| Description | Royal Society of Biology Biology week talk, Winchester, 10/10/2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Talk organized by Royal Society of Biology as part of Biology Week. This one in Winchester, audience was general public with strong representation of school-age. Questions and discussion during and after formal talk. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Rydal Hall Flavivirus meeting - Mathilde Laureti |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Conference to share research and break through in the Flavivirus field. Provide the opportunity for collaboration with National research groups. |
| Year(s) Of Engagement Activity | 2022 |
| Description | SATRO Mentoring Scheme Ash Manor School |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Fortnightly mentoring activity for student's soft skill and career development. |
| Year(s) Of Engagement Activity | 2019,2020 |
| Description | SMBE 2018 meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation entitled "Phylogenetically young genes and their function in Anopheles mosquitoes" given during the Society for Molecular Biology and Evolution 2018 meeting (8-12 July 2018) in Yokohama, Japan. Discussions held with potential collaborators on joined future research projects. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.smbe2018.jp/ |
| Description | STEM Day - Speed interviews and Careers Day 2018 - BA |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | STEM Outreach Event (Farnborough, 9th November) |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | See web link |
| Year(s) Of Engagement Activity | 2016 |
| Description | Scheduled Twitter session with University of Nottingham students on professional skills for biosciences |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Undergraduate students |
| Results and Impact | Hour-long Twitter chat on Friday 12th May with biotechnology students, microbiology students, animal science students interested in animal diseases and animal welfare and behaviours and agriculture students interested in livestock. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://twitter.com/search?q=%23biosciprofskills |
| Description | School talk of Vectors |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Virtual presentation as part of school Science Day. Talked about insect vectors of pathogens |
| Year(s) Of Engagement Activity | 2021 |
| Description | School visit |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Gave a presentation to a group of students about research performed at the Pirbright Institute and discussed different aspects of scientists' work. |
| Year(s) Of Engagement Activity | 2017 |
| Description | School visit (Farnborough) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Gave a presentation to a group of students about research performed at the Pirbright Institute and discussed various aspects of scientists' work. |
| Year(s) Of Engagement Activity | 2018 |
| Description | School visit (Tillingbourne) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Gave a presentation to a group of students about role of insects in the environment; guided students in collection of insects and other invertebrates, and identification of collected material. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Scientific Presentation: SOVE lecture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Society of Vector Ecology Presentation 'The Gnatwork'. 6th October 2017 over 150 attendance. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.uibcongres.org/sove2017/ |
| Description | Site tour with Department of Trade and Industry |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Tour/site visit with Department of Trade and Industry (25 people attending) |
| Year(s) Of Engagement Activity | 2017 |
| Description | Skillfluence interview |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Interview with Skillfluence to provide real-world examples and experience to inform course materials for a programme for "Future Innovators" |
| Year(s) Of Engagement Activity | 2021 |
| Description | Speaker UK Vector-borne Disease Meeting (Liverpool - online) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation given on 23/11/20. Major outcome was discussion around climate-related impacts on Culicoides populations. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Sutton College Lecture (Enjoy your retirement) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Talk to group on virus outbreaks (Enjoy your retirement) - 16 people & class coordinator. Included simulation of a virus outbreak. |
| Year(s) Of Engagement Activity | 2019 |
| Description | TW Society for General Microbiology |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Society for General Microbiology 2015 Meeting |
| Year(s) Of Engagement Activity | 2015 |
| Description | Talk (Christopher Sanders): Lancaster University (Culicoides and their role as vectors) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk give to academic audience through invited lecture. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Talk (Christopher Sanders): Virus Transmission and Vector Competence of Culiocides (Royal Entomological Society Annual Meeting) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Annual Meeting of the ROyal Entomological Society presentation. Held at LSHTM on 21st August 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Talk on "Emerging Diseases" at BBSRC Cross-Institute workshop, Roslin Institute |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Talk on Emerging Diseases in the context of a workshop on Future of Livestock in Food Production |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.ed.ac.uk/roslin/news-events/latest-news/future-of-livestock-production-in-the-spotlight |
| Description | Talk on "Spread and control of lumpy skin disease virus in Europe" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at Bill & Melinda Gates Foundation workshop on lumpy skin disease, Dubai, 16-18 November 2022 |
| Year(s) Of Engagement Activity | 2022 |
| Description | Talk to Brazilian National institute of Molecular Entomology |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Research talk describing the role of Culiocies biting midges in BTV transmission. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Talk to clinicians at Hospital for Tropical Diseases |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk to clinicians at Hospital for Tropical Diseases, London, regardingcurrent and future methods for controlling mosquito-borne disease based on mosquito genetics |
| Year(s) Of Engagement Activity | 2020 |
| Description | The impact of BTV-4 infection on the volatilome of cattle and sheep: a proof of concept. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Claire Cayol, PDRA on the grant presented at the Epizone conference in Barcelona in May 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Tillingbourne Bug Hunt |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Local entomology event for general public - changes in public attitudes and stimulating increased interest in insects/entomology and research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Tillingbourne Bug Hunt (Christopher Sanders) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Insect identification event with general public (primarily schools). |
| Year(s) Of Engagement Activity | 2018 |
| Description | Tillingbourne Year 3 Science Day 2018 - EL |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Stimulating increased interest in research |
| Year(s) Of Engagement Activity | 2018 |
| Description | Tillingbourne bug hunt. New Rd, Chilworth, Guildford GU4 8NB |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Stimulating increased interest in science and research. Good interest and engagement. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Tour of Philip Mellor Insectary (Country Land and Business Association) |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Third sector organisations |
| Results and Impact | Tour of Philip Mellor Insectary with Country Land and Business Association (20 people) |
| Year(s) Of Engagement Activity | 2017 |
| Description | UAR interview 13/05/2021 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Interview for Understanding Animal Research regarding genetic research on mosquitoes to prevent spread of mosquito-borne diseases |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.understandinganimalresearch.org.uk/news/fighting-the-worlds-most-deadly-animal-the-mosqu... |
| Description | UEA LGBT History Month article |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Undergraduate students |
| Results and Impact | I was interviewed for a student magazine feature showcasing my work as part of LGBT History month. |
| Year(s) Of Engagement Activity | 2023 |
| Description | UK Microbiological Society Fleming Showcase |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Described mosquito-based approaches to microbiologists and others |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://microbiologysociety.org/news/society-news/fleming-showcase-speaker-profile-professor-luke-al... |
| Description | UK vector meeting 2018 (Organising committee; Chair) (December; John Innes Centre, UK) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chaired and helped organise meeting on UK Vector-borne Diseases as part of committee. Included reviewing talks and inviting speakers. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.hpruezi.nihr.ac.uk/media/29013/master-draft-vbd-programme-with-titles-oct18_.pdf |
| Description | UK-India bioinformatics workshop |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | On February 9 2018 Pirbright organised a "UK-India bioinformatics workshop" in order to foster ties between Indian and UK bioinformaticians working in the field of livestock and crop research. Paolo Ribeca gave a talk on "Bioinformatics and sequencing at Pirbright". |
| Year(s) Of Engagement Activity | 2018 |
| Description | UKRI Festival of Tomorrow |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Talk and stand on viruses and engineering mosquitoes |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.ukri.org/news/showcasing-incredible-discoveries-at-swindon-festival-of-tomorrow/ |
| Description | University of Surrey Vet School Open Day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | Institute stand at Surrey Vet School - introducing the institute to prospective vet students |
| Year(s) Of Engagement Activity | 2018 |
| Description | VC discussions |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Briefed venture capital groups on landscape around genetic vector management and related products |
| Year(s) Of Engagement Activity | 2020 |
| Description | VS Mosquitoes under the micoscope |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | Series of talks called mosquitoes under the microscope. Talks presented to the general public. |
| Year(s) Of Engagement Activity | 2020,2021 |
| Description | Winston Churchill Careers Fair. Winston Churchill School, Hermitage Road, St Johns, Woking, Surrey, GU21 8TL |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | AS attended and presented at this event to stimulate increased interest in science and research. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Wired interview |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Media interview regarding use of gene drive systems in mosquitoes |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.wired.co.uk/article/genetically-modified-mosquitoes-gene-drive |
| Description | Workshop 1: Minimum Information for Reporting Arthropod Infection Studies |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A workshop was held as part of the VectorBiTE RCN annual meeting at Asilomar in CA. Attendance was roughly 60 people, mostly users of data resulting from experimental arthropod infection studies or arthropod ecological datasets. AW gave a presentation describing the objectives of the grant and then we formed breakout groups to discuss potential factors to report and their importance for different categories of users. The feedback was used to review and update the draft standards document before the second workshop as ASTMH's Trop Med meeting in New Orleans in October. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Workshop 2: Minimum Information for Reporting Arthropod Infection Studies |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A workshop was organised in collaboration with members of the ASTMH's Advisory Committee on Arthropod-borne Viruses (ACAV) at the start of the 2018 Trop Med annual meeting and was advertised via social media and society and project mailing lists. Around 30 people attended, mostly from the US but with representation from Asia, Europe and South America, and a mixture of senior academics, junior faculty and students. AW gave a brief introduction to the objectives of the workshop and AW, assisted by LH (a postdoc at Pirbright), helped participants pilot the questionnaire before its formal launch. Feedback was positive and used to refine the questionnaire before it was launched in November. As a result of specific points raised in the feedback, the survey was translated into French and Spanish and these versions were launched simultaneously to support involvement by a broader audience. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Workshop 3: Minimum Information for Reporting Arthropod Infection Studies |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A workshop was organised during the biennial UK VBD meeting in Norwich to improve awareness of the survey and increase completion. A short presentation was given by LH, a postdoc at Pirbright who has been assisting with the development of the questionnaire and standards documentation (as AW is leaving Pirbright in December) and then breakout groups formed to discuss particular challenges and any suggested changes as well as pathways to increasing the chances of uptake of the resulting guidelines. The feedback was recorded and will influence the resulting report/manuscript. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Workshop on Ecology and Evolution of Infectious Diseases |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | NSF-BBSRC workshop on Ecology and Evolution of Infectious Diseases held at Emory University, Atlanta, U.S.A, 4-6 June 2022 |
| Year(s) Of Engagement Activity | 2022 |
| Description | World Dengue Day |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | This was the inaugural World Dengue Day, an annual multi-day series of events to raise awareness of the global impact of dengue. The event raised awareness of dengue globally and sparked interest from a number of attendees in our research. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.adva.asia/world-dengue-day-2021/ |
| Description | YS Winston Churchill School Careers event |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Careers Fair at large secondary school, comprehensive with 1500 pupils. Stand set up which generated lots of discussion and interest from the students. |
| Year(s) Of Engagement Activity | 2021 |
| Description | eMergence autumn 2019 |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Article for the MSD online publication eMergence. |
| Year(s) Of Engagement Activity | 2019 |
| URL | http://www.emergence-msd-animal-health.com/ |
| Description | email interview with journalist (Sukanya Charuchandra, The Wire) |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Email interview for journalist for "The Wire" - an online technology-focused media outlet. Helped provide context and impact for the resulting piece. https://thewire.in/the-sciences/scientists-identify-protein-that-mosquitoes-need-to-lay-viable-eggs |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://thewire.in/the-sciences/scientists-identify-protein-that-mosquitoes-need-to-lay-viable-eggs |
| Description | international workshop on "Self-Propagation of Artificial Genetic Elements: Gene Drives, Risks & Tipping Points Bremen 19-20 June 2018 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Workshop considering regulatory, social and technical environment for gene drive systems in insects, primarily for German and other EU regulatory and political entities. |
| Year(s) Of Engagement Activity | 2018 |