Cloning wheat rust resistance genes by sequence capture on structured populations
Lead Research Organisation:
John Innes Centre
Department Name: Contracts Office
Abstract
Rust resistance genes in cereal crops are often overcome within a few seasons when deployed one at a time. Introgressing multiple resistance genes into a cultivar is one strategy that may contribute to more durable resistance; however, when this process is done by traditional breeding methods it involves long breeding trajectories and can result in linkage drag due to deleterious alleles. We are pursuing a transgenic approach to control wheat stem rust. Our strategy is to isolate multiple novel stem rust resistance (Sr) genes and deploy them in combination at a single transgene locus in wheat. This strategy should avoid linkage drag and ensures that the genes stay together, thus avoiding single genes again being exposed to the pathogen. This project will support our ongoing efforts to combine targeted sequence capture, high throughput sequencing and comparative genomics on genetically structured populations to speed up the cloning of Sr genes from diploid relatives of wheat and from wheat alien introgression lines.
Organisations
- John Innes Centre, United Kingdom (Collaboration, Lead Research Organisation)
- Earlham Institute, NORWICH (Collaboration)
- University of California, Berkeley (Collaboration)
- Ilam University (Collaboration)
- Limagrain (Collaboration)
- National Inst of Agricultural Botany (Collaboration)
- Punjab Aricultural University (Collaboration)
- Heliospectra AB (Collaboration)
- Academy of Sciences of the Republic of Tajikistan (Collaboration)
- Novogene Corporation (Collaboration)
- KWS UK (Collaboration)
- DIALUNOX (Collaboration)
- U.S. Department of Agriculture USDA (Collaboration)
- Helmholtz Zentrum München (Collaboration)
- Commonwealth Scientific and Industrial Research Organisation (Collaboration)
- 2Blades Foundation (Collaboration)
- Syngenta International AG (Collaboration)
- University of Maryland, United States (Collaboration)
- University of Minnesota, United States (Collaboration)
- Bayer (Collaboration)
- Kansas State University, United States (Collaboration)
People |
ORCID iD |
| Brande Bruce Wulff (Principal Investigator) |
Publications
Adamski NM
(2020)
A roadmap for gene functional characterisation in crops with large genomes: Lessons from polyploid wheat.
in eLife
Bevan MW
(2017)
Genomic innovation for crop improvement.
in Nature
Hafeez AN
(2021)
Creation and judicious application of a wheat resistance gene atlas.
in Molecular plant
Hao Y
(2020)
Harnessing Wheat Fhb1 for Fusarium Resistance.
in Trends in plant science
Hickey LT
(2019)
Breeding crops to feed 10 billion.
in Nature biotechnology
Hiebert CW
(2020)
Stem rust resistance in wheat is suppressed by a subunit of the mediator complex.
in Nature communications
Kangara N
(2020)
Mutagenesis of Puccinia graminis f. sp. tritici and Selection of Gain-of-Virulence Mutants.
in Frontiers in plant science
Kawashima CG
(2016)
A pigeonpea gene confers resistance to Asian soybean rust in soybean.
in Nature biotechnology
Luo M
(2021)
A five-transgene cassette confers broad-spectrum resistance to a fungal rust pathogen in wheat.
in Nature biotechnology
| Title | 2nd Prize in Engaging Images Art Competition, The Sainsbury Centre for Visual Arts |
| Description | Josh Waites' artwork based on the MARPLE wheat rust diagnostic tool from the @Saunders_Lab came second in the Engaging Images Art Competition. Due to MARPLE's use in Ethiopia, he painted it in a traditional orthodox Ethiopian art style. It was displayed at The Sainsbury Centre for Visual Arts during the month of December 2019. |
| Type Of Art | Artwork |
| Year Produced | 2019 |
| Impact | Not aware of any. |
| URL | https://twitter.com/JoshOWaites/status/1203311578571059200 |
| Title | Blog on "Wild wheat, plant genomics, and food security" |
| Description | I wrote a blog for the Global Engage conference "Plant Genomics and Gene Editing Congress: Europe". |
| Type Of Art | Creative Writing |
| Year Produced | 2020 |
| Impact | The blog was well received and widely tweeted. |
| URL | http://www.global-engage.com/agricultural-biotechnology/wild-wheat-plant-genomics-and-food-security/ |
| Title | What is AgRenSeq |
| Description | An animation describing our enabling technology "AgRenSeq" for rapidly discovering and cloning disease resistance genes in plant genomes. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2019 |
| Impact | The Youtube video has been viewed 1919 times since it was uploaded in February 2019 (i.e. nearly two years ago). |
| URL | https://www.youtube.com/watch?v=xefrjg5Y_Ug |
| Title | Wrestling genes out of the giant barley and wheat genomes |
| Description | Blog for general science audience on how to rapidly clone genes from wheat or barley |
| Type Of Art | Creative Writing |
| Year Produced | 2016 |
| Impact | Postive feedback from friends and colleagues. |
| URL | http://blogs.biomedcentral.com/on-biology/2016/10/24/wrestling-genes-out-of-the-giant-barley-and-whe... |
| Description | This grant helped to refine MutRenSeq, a technique for accelerating identification (molecular cloning) of disease resistance genes in wheat. In the past, cloning resistance genes in wheat typically took 5-10 years. With MutRenSeq this can now be done in just 2 years. Note added: 08 March 2018: This technology, and others which we have developed, is fuelling an exciting revolution in resistance gene cloning in Triticeae, in particular wheat, wheat wild relatives, barley, and wild barley. This will likely provide the material needed to engineer multi resistance gene stacks, which, providing the socio-political impasse on GM crops, and in particular GM wheat, could be overcome, could lead to a revolution in resistance gene deployment to achieve more durable resistance and less dependence on pesticides. |
| Exploitation Route | There are ongoing discussions between the 2Blades Foundation, USA (a co-founder of my research), CIMMYT (a public good breeding institute serving the developing world), and the CSIRO-Australia, for engineering a multi-transgene stack containing multiple broad-spectrum stem rust resistance genes for more durable resistance to this devastating disease of wheat. |
| Sectors | Agriculture, Food and Drink |
| Description | The findings helped support a GM field trial for stem rust resistance in Minnesota, USA. See: http://www.global-engage.com/agricultural-biotechnology/wild-wheat-plant-genomics-and-food-security/ http://2blades.org/2019/03/12/wheat-lines-from-2blades-csiro-and-umn-exhibit-exceptional-stem-rust-resistance-in-the-field/ Note added 10 February 2021. The manuscript reporting these findings was recently published in Nature Biotechnology: https://www.nature.com/articles/s41587-020-00770-x |
| Sector | Agriculture, Food and Drink,Environment |
| Impact Types | Societal,Policy & public services |
| Description | 2Blades Foundation |
| Amount | $20,000 (USD) |
| Organisation | 2Blades Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 06/2017 |
| End | 07/2018 |
| Description | A multi-R gene stack for durable resistance to wheat stem rust (with 2Blades Foundation) |
| Amount | £939,147 (GBP) |
| Organisation | Two Blades Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 06/2014 |
| End | 06/2017 |
| Description | BBSRC "Impact Acceleration Account" |
| Amount | £13,078 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2017 |
| End | 02/2018 |
| Description | BBSRC - ISCF Agri-food Technology Catalyst |
| Amount | £29,943 (GBP) |
| Funding ID | BB/SCA/JIC/17 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2017 |
| End | 02/2018 |
| Description | BBSRC NRP-DTP iCASE |
| Amount | £113,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2018 |
| End | 09/2022 |
| Description | BBSRC iCASE |
| Amount | £113,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2018 |
| End | 09/2022 |
| Description | Cloning and characterization of Sr43 and stem rust resistance genes SrA, SrB, SrC and SrD from Aegilops sharonensis |
| Amount | £100,165 (GBP) |
| Organisation | Two Blades Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 06/2019 |
| End | 10/2020 |
| Description | Doctoral Trainingship Programme |
| Amount | £97,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2017 |
| End | 09/2021 |
| Description | FSOV |
| Amount | € 279,216 (EUR) |
| Organisation | French Wheat Research Fund (FSOV) |
| Sector | Charity/Non Profit |
| Country | France |
| Start | 02/2017 |
| End | 01/2020 |
| Description | FSOV |
| Amount | € 255,538 (EUR) |
| Organisation | French Wheat Research Fund (FSOV) |
| Sector | Charity/Non Profit |
| Country | France |
| Start | 02/2017 |
| End | 01/2020 |
| Description | GCRF-IAA funding: Wheat blast resistance partnership development with Bangladesh |
| Amount | £17,486 (GBP) |
| Funding ID | BB/GCRF-IAA/17/11 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2016 |
| End | 03/2017 |
| Description | Global Challenges Research Fund |
| Amount | £316,622 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2017 |
| End | 07/2018 |
| Description | Global Challenges Research Fund - Data and Resources |
| Amount | £897,694 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2016 |
| End | 07/2017 |
| Description | John Innes Centre KEC Innovation Fund |
| Amount | £40,499 (GBP) |
| Organisation | John Innes Centre |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 07/2015 |
| End | 12/2016 |
| Description | Marie Sklodowska Curie Action International Training Network |
| Amount | € 238,507 (EUR) |
| Organisation | Marie Sklodowska-Curie Actions |
| Department | Initial Training Networks (ITN) |
| Sector | Charity/Non Profit |
| Country | Global |
| Start | 01/2016 |
| End | 12/2019 |
| Description | Monsanto Beachel-Borlaug International Scholarship |
| Amount | $220,000 (USD) |
| Funding ID | MBBIS 06-400258-12580 |
| Organisation | Monsanto |
| Sector | Private |
| Country | United States |
| Start | 06/2016 |
| End | 06/2020 |
| Description | Newton Institutional Links Grant |
| Amount | £299,973 (GBP) |
| Organisation | Newton Fund |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 03/2020 |
| Description | Norwich Research Park Translational Fund |
| Amount | £41,272 (GBP) |
| Organisation | Norwich Research Park |
| Sector | Private |
| Country | United Kingdom |
| Start | 11/2016 |
| End | 06/2017 |
| Description | Safeguarding our daily bread from wheat rust diseases |
| Amount | £2,930 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2019 |
| End | 08/2019 |
| Description | Understanding and exploiting genetic diversity in wheat for yellow rust resistance |
| Amount | £113,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 12/2023 |
| Title | Open Wild Wheat raw sequences |
| Description | We provide access to whole genome shotgun sequences of a genetically diverse panel of 151 accessions of Aegilops tauschii generated under the aegis of the Open Wild Wheat Consortium (www.openwildwheat.org). |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | We have used the data to implement a 'shotgun' genome-wide association study (GWAS) pipeline for rapid gene discovery and identificaiton. Based on this, we have identified candidate genes for stem rust, wheat blast and trichome density. We have had very many requests from the community to implement this technology, and we expect it will fuel an exponential rise in cloned genes within the Triticeae. |
| URL | https://opendata.earlham.ac.uk/wheat/under_license/toronto/Wulff_2018-01-31_OWWC/ |
| Description | Collaboration with Jonathan Jones funded by Betty and Gordon Moore Foundation via 2Blades Foundation |
| Organisation | The Sainsbury Laboratory |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We have used RenSeq to genotype 200 Watkins wheat landrace lines. |
| Collaborator Contribution | My colleague Jonathan Jones kindly offered to collaborate on the sequence-configuration of our Watkins wheat landrace panel by paying for RenSeq genotyping of 100 lines. |
| Impact | This collaboration has allowed us to increase the size of our sequence configured panel from 200 to 300. This will improve the resolution wich which we can discover and clone resistance genes in the panel. |
| Start Year | 2018 |
| Description | Identification of rust resistance genes in wild emmer wheat |
| Organisation | 2Blades Foundation |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | My own group will be providing bioinformatics in the form of k-mer-based whole genome shotgun association genetics to identify candidate disease resistance genes from wild emmer. We will also engineer binary vector constructs for wheat transformation. |
| Collaborator Contribution | The 2Blades Foundation have brought overall management of the project to the partnership. They will also be responsible for handling IP resulting from the work. Kansas State University and University of Minnesota will configure and sequence the wild wheat diversity panel and phenotype it with several isolates of the wheat stem rust, stripe rust and leaf rust pathogens. |
| Impact | This collaboration has only recently started, so it is too early to list outputs. |
| Start Year | 2020 |
| Description | Identification of rust resistance genes in wild emmer wheat |
| Organisation | Kansas State University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | My own group will be providing bioinformatics in the form of k-mer-based whole genome shotgun association genetics to identify candidate disease resistance genes from wild emmer. We will also engineer binary vector constructs for wheat transformation. |
| Collaborator Contribution | The 2Blades Foundation have brought overall management of the project to the partnership. They will also be responsible for handling IP resulting from the work. Kansas State University and University of Minnesota will configure and sequence the wild wheat diversity panel and phenotype it with several isolates of the wheat stem rust, stripe rust and leaf rust pathogens. |
| Impact | This collaboration has only recently started, so it is too early to list outputs. |
| Start Year | 2020 |
| Description | Identification of rust resistance genes in wild emmer wheat |
| Organisation | University of Minnesota |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | My own group will be providing bioinformatics in the form of k-mer-based whole genome shotgun association genetics to identify candidate disease resistance genes from wild emmer. We will also engineer binary vector constructs for wheat transformation. |
| Collaborator Contribution | The 2Blades Foundation have brought overall management of the project to the partnership. They will also be responsible for handling IP resulting from the work. Kansas State University and University of Minnesota will configure and sequence the wild wheat diversity panel and phenotype it with several isolates of the wheat stem rust, stripe rust and leaf rust pathogens. |
| Impact | This collaboration has only recently started, so it is too early to list outputs. |
| Start Year | 2020 |
| Description | Open Wild Wheat Consortium |
| Organisation | 2Blades Foundation |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Academy of Sciences of the Republic of Tajikistan |
| Department | Institute of Botany, Plant Physiology and Genetics |
| Country | Tajikistan |
| Sector | Public |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Bayer |
| Country | Germany |
| Sector | Private |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Commonwealth Scientific and Industrial Research Organisation |
| Country | Australia |
| Sector | Public |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | DIALUNOX |
| Country | Germany |
| Sector | Private |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Earlham Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Heliospectra AB |
| Department | Institute Cereal Crops Improvement, Tel Aviv |
| Country | Israel |
| Sector | Private |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Helmholtz Zentrum München |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Ilam University |
| Country | Iran, Islamic Republic of |
| Sector | Academic/University |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | KWS UK |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Kansas State University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Limagrain |
| Country | France |
| Sector | Private |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | National Institute of Agronomy and Botany (NIAB) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Novogene Corporation |
| Country | China |
| Sector | Private |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Punjab Aricultural University |
| Country | India |
| Sector | Academic/University |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | Syngenta International AG |
| Department | Syngenta Crop Protection |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | U.S. Department of Agriculture USDA |
| Country | United States |
| Sector | Public |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | University of California |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | University of Maryland |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Description | Open Wild Wheat Consortium |
| Organisation | University of Minnesota |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | We conceived and founded the Open Wild Wheat Consortium, drafted grant proposals, obtained and managed pledges for funds from consortium members (private and public), designed and published the OWWC website, configured the Aegilops tauschii panel, extracted DNA, bulked up seed, distributed seed to >10 collaborators/members, sent DNA for whole genome shotgun sequencing, made raw data available through Grassroots Repository (in collaboration with Earlham Institute), generated draft assemblies of core accessions (in collaboration with CLC), establised whole genome shotgun k-mer-based association genetics pipeline, generated phenotypes for wheat blast (in collaboration with Paul Nicholson) and wheat rusts (in collaboration with Brian Steffenson, Xianming Chen and Jim Kolmer) and drafted manuscript synopsis. |
| Collaborator Contribution | Partners provided funds for sequencing, helped to manage sequencing (Novogene), provided sequencing discount (Novogene), germplasm (KSU, NIAB, CSIRO, UC Davis), helped configure panel (KSU), helped to store and distribute seed (GRU), and contributed with phenotyping. |
| Impact | This project has brought together a large, international group of people with a common interest in mining wild wheat relatives for useful genetic variation. We have established the primary tools, resources, methods and pipeline to go from phenotypes in a wild wheat relative, identifying the underlying genes to studying the relevance of those genes in adapted germplasm. |
| Start Year | 2016 |
| Title | Stem rust resistance genes and methods of use |
| Description | Compositions and methods and for enhancing the resistance of wheat plants to wheat stem rust caused by Puccinia graminis f. sp. tritici are provided. The compositions comprise nucleic acid molecules encoding resistance (R) gene products and variants thereof and plants, seeds, and plant cells comprising such nucleic acid molecules. The methods for enhancing the resistance of a wheat plant to wheat stem mst comprise introducing a nucleic acid molecule encoding an R gene product into a wheat plant cell. Additionally provided are methods for using the wheat plants in agriculture to limit wheat stem rust. |
| IP Reference | US20200362367A1 |
| Protection | Patent application published |
| Year Protection Granted | 2020 |
| Licensed | No |
| Impact | None to date. |
| Title | WHEAT STEM RUST RESISTANCE GENES AND METHODS OF USE |
| Description | Compositions and methods and for enhancing the resistance of wheat plants to wheat stem rust caused by Puccinia graminis f. sp. tritici are provided. The compositions comprise nucleic acid molecules encoding resistance (R) gene products and variants thereof and plants, seeds, and plant cells comprising such nucleic acid molecules. The methods for enhancing the resistance of a wheat plant to wheat stem rust comprise introducing a nucleic acid molecule encoding an R gene product into a wheat plant cell. Additionally provided are methods for using the wheat plants in agriculture to limit wheat stem rust. |
| IP Reference | WO2017024053 |
| Protection | Patent application published |
| Year Protection Granted | 2017 |
| Licensed | No |
| Impact | The genes have been added to multi-R gene stacks and transformed into wheat and barley. These will be field trialled in Minnesota, USA in the 2018 growing season. |
| Title | AgRenSeq - GitHub |
| Description | AgRenSeq is a pipeline to identify candidate resistance (R) genes in plants directly from a diversity panel. The diversity panel needs to be sequenced (R gene enrichment sequencing - RenSeq) and phenotyped. Phenotype scores need to be converted to AgRenSeq scores that assign positive values to resistance and negative values to suscetibility. An intermediate phenotype should have an AgRenSeq score close to zero. For RenSeq you will need a bait library that targets R genes in your plant species. A bait library for Aegilops tauschii can be found here. We reccomend Arbor biosciences for synthesis of baits. They also offer the enrichment service. |
| Type Of Technology | Software |
| Year Produced | 2018 |
| Impact | Requests for collaboration from academia and industry. |
| Title | MutRenSeq Mutant Hunter |
| Description | The MutRenSeq Mutant Hunter is a pipeline to combine resistance gene enrichment sequencing (RenSeq) with EMS mutant screens to identify NLR-type resistance genes. |
| Type Of Technology | Software |
| Year Produced | 2015 |
| Open Source License? | Yes |
| Impact | This pipeline has resulted in collaborations (some on responsive mode grants), research agreements, and further funding (e.g. from the 2Blades Foundation, USA). |
| URL | https://github.com/steuernb/MutantHunter/ |
| Title | k-mer GWAS |
| Description | Python code for k-mer-based reference free genome wide association mapping on whole genome shotgun sequence-configured diversity panels. |
| Type Of Technology | Software |
| Year Produced | 2021 |
| Open Source License? | Yes |
| Impact | 1) Landmark paper published in Nature Biotechnology (doi.org/10.1038/s41587-021-01058-4) under the aegis of the Open Wild Wheat Consortium. 2) Patent filed on method development |
| URL | http://doi.org/10.1038/s41587-021-01058-4 |
| Description | 5th Plant Genomics Workshop, Amsterdam |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presented my work on rapid gene cloning and speed breeding at the 5th Plant Genomics Workshop, Amsterdam. This lead to questions and discussion with other scientists and representatives from industry, and I was invited back to present again in 2018, as well as invited to the advisory board. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Annual Science Meeting 2018, JIC and TSL |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was called upon to give an update of my work at the JIC and TSL Annual Science Meeting 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | BMGF Grand Challenges Meeting, Berlin, Germany |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to the BMGF Grand Challenges Meeting, in Berlin, Germany. This has since led to further interactions with the BMGF and DFID funded DGGW project, and a request for a workshop at the next DGGW meeting which will be held in the John Innes Centre in 2020. |
| Year(s) Of Engagement Activity | 2019 |
| Description | CerealPath PhD Course on Scientific Soft Skills |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | I co-organised and taught a course on scientific soft skills for a group of PhD students from the EU funded CerealPath programme. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://cerealpath.eu/ |
| Description | Colloquium, Max-Planck Institute for Plasma Physics, Greifswald, Germany |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Based on my recent opinion pieces on GM crops published in Science I was called upon by physicists in the Max-Planck Institute for Plasma Physics, Germany, to give Colloquim presentation. My presentation was recorded and in the ensuing week I was told it was viewed more than 350 times! |
| Year(s) Of Engagement Activity | 2020 |
| Description | Cranfield University |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | I was called upon to give a lecture to MSc students on the Cranfield University bioinformatics course. I was asked to come back again in May for a two day visit to teach scientific soft skills for early career scientists. |
| Year(s) Of Engagement Activity | 2019 |
| Description | DivSeek Workshop |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was called upon at short notice to give a presentation at the DivSeek workshop on how to exploit germplasm collections for rapid trait identificaiton and deployment. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Feeding the Future: Can we protect crops sustainably? Society of Chemical Industry, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was called upon to give a talk about the case for GM wheat for disease management, by the Society of Chemical Industry (https://www.soci.org/). They have a vested interest in this topic given that many of their stake holders are affiliated with the agro-chemical (pesticide) industry. I had very positive feedback from my presentation, e.g. see below: "Dear Brande, I had a hunch that your talk would be a highlight for me and I was not disappointed. There was so much in it that I enjoyed listening to and I learned so much. For me, it came down to the key question of 'Can we pull out special genes from wild relatives and insert them into elite wheat?' I was pleased to hear you say that the answer is 'yes' even though there are substantial technical issues to overcome about poor recombination. The new sequencing and mathematical techniques are giving us real prospects for taking things forward. Your example of the variety with the 5 stacked genes was inspiring. If we can do this once, how many more times can we do it? You have inspired me to want to learn so much more. Thank you very much. Very best wishes, James James Garratt CSci Managing Director" |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.soci.org/events/protecting-crops-in-a-challenging-future |
| Description | Food Ingreedients: "Speed cloning: Transforming crop disease protection with higher yielding, resilient "elite crops"" |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | I was interviewed by the online magazine "Food Ingredients" about protecting crops with cloned resistance genes. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.foodingredientsfirst.com/news/speed-cloning-transforming-crop-disease-protection-with-hi... |
| Description | Group member Postdoc Kumar Gaurav invited to present Keynote Lecture at EuroBiotech, Kraków, Poland, 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Keynote Lecture, EuroBiotech, Kraków, Poland, 2019 |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.eurobiotech.krakow.pl/gb/program-x/program.html |
| Description | Huazhong Agricultural University, China |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | I was called upon by one of my collaborators to present my work at Huazhong Agricultural University, China |
| Year(s) Of Engagement Activity | 2020 |
| Description | Interview by Deutchlandfunk (German radio station) |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | In the wake of my Nature Biotechnology paper on rapid resistance gene cloning by associaiton genetics, I was interviewed by Deutchlandfunk, a german radio station equivalent to Radio BBC 4 in the UK. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.deutschlandfunk.de/resistenzgene-bei-pflanzen-hilfe-von-der-starken.676.de.html?dram:art... |
| Description | Interview by Jerome Starkey, The Times |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Following our press release on the appearance of stem rust in the UK for the first time in 50 years, I was interviewed by The Times correspondent Jereme Starkey. This resulted in a short article in The Times. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.thetimes.co.uk/article/plague-that-scared-the-romans-is-back-g6nzm5d0k |
| Description | Interview with Newsweek on genetic diversity |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | I was interviewed by Newsweek on the importance of genetic diversity in crops. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.newsweek.com/feed-world-scientists-have-plan-save-chickpeas-destruction-806925 |
| Description | Interviews with press and media on speed breeding |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | JIC External Relations department released a press release on our work on 'speed breeding'. This sparked considerable attention from the press and media. I expect I gave about 20 interviews in the ensuing days, featured on BBC Look East, the local press, two national newspapers (The Times and The Guardian), Newsweek, as well as countless other media outlets across the world, including in Japanese, Chinese and Arabic. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invitation to present work at Wiersum Plantbreeding, The Netherlands |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | I was invited to visit Wiersum Plantbreeding in the Netherlands. We discussed potential future collaborative work around the concept of a resistance gene atlas for wheat. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited presentaiton (plenary session) at the Molecular Plant Microbe Interactions congress in Glasgow 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to give a presentation of my work at the 2019 MPMI meeting in Glasgow. Based on this, I have since received two additional invitations to give seminars in Oxford University and Edinburgh University. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.ismpmi.org/Congress/Pages/default.aspx |
| Description | Invited presentaiton at G20 Wheat Meeting in Frankfurt |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to give a presentation at the G20 wheat meeting in Frankfurt. The presentation sparked questions and led to requests for futher information and collaboration. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.bmel.de/SharedDocs/TermineVeranstaltungen/EN/16-12-08-InternationalWheatCongress.html |
| Description | Invited presentation at 7th Central European Congress of Life Sciences Eurobiotech, Krakow, Poland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | My postdoc Kumar Gaurav was invited to give a Keynote Lecture at the the 7th Central European Congress of Life Sciences Eurobiotech, Krakow, Poland. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.eurobiotech.krakow.pl/gb/ |
| Description | Invited presentation at AgriTech East, NIAB, Cambridge, UK |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | AgriTech East dissemination activity to local farmers, breeders and industry stake holders on rust diseases of wheat. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.cambridgenetwork.co.uk/events/pollinator-rusts-and-other-cereal-killers/ |
| Description | Invited presentation at BASF, Belgium |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | I was invited to BASF in Ghent, Belgium to present my work on rapid gene discovery and cloning in crops. We later discussed potential collaborations. This has resulted in further requests for information and discussions on collaboration. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Invited presentation at BeCA-ILRI (Nairobi, Kenya) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | This presentation sparked questions and discussions. Expansion of my scientific network and opportunities for future collaborations. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Invited presentation at Elsoms Ltd, Spalding |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Industry/Business |
| Results and Impact | I was invited to give a presentation to the vegatble and herb breeding company Elsoms Ltd in Spalding, Lincolnshire. The presentation lead to request for further information and |
| Year(s) Of Engagement Activity | 2016 |
| Description | Invited presentation at IPK, Gatersleben, Germany |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | I gave a presentation on engineering resistance to the stem rust fungus in wheat using cloned resistance genes from wild grasses. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Invited presentation at Institute of Experimental Botany, Czech Republic |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to the Institute of Experimental Botany in the Czech Republic to give a presentation about my work on rapid gene discovery and cloning in Triticeae. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited presentation at Julius Kühn Institute, Quedlinburg, Germany |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Policymakers/politicians |
| Results and Impact | I gave a presentation on engineering resistance to the stem rust fungus in wheat using cloned resistance genes from wild grasses. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Invited presentation at KAUST, Thuwal, Saudi Arabia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | I visited KAUST to present my work. This has resulted in offers of further collaboration. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Invited presentation at Kew |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to give a short seminar on how to exploit genetic variation in crop wild relatives at a joint workshop organised between the John Innes Centre and Kew. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited presentation at Key's Symposium, Keygene, Netherlands |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | I was invited to give a presentation on my work at Keygene, The Netherlands. This resulted in requests for further information and interactions. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited presentation at National Institute of Botany |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | I gave a presentation on next generation disease resistance breeding in wheat. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Invited presentation at Plant Sciences Department, University of Oxford |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | I was invited to present my work at the Plant Sciences Department at the University of Oxford. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited presentation at Plant and Animal Genome Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | My postdoc, Kumar Gaurav, was invited to present our work on rapid gene cloning at PAG. This resulted in requests for further collaboration from groups in USA. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited presentation at Pwani Univeristy, Kenya |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | As part AfriPlantSci, a two-week course on plant sciences for African scientists, I was invited to give a presentation at Pwani University, Kenya describing my research on rapid gene cloning and speed breeding in cereals. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://acaciaafrica.org/afriplantsci/ |
| Description | Invited presentation at Technical University of Munich |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to give a presentation at the TUM on my speed breeding and rapid gene cloning work in cereals. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://portal.mytum.de/termine/Event.2019-03-20.1464449129/event_view? |
| Description | Invited presentation at The Sainsbury Laboratory |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to present my work in The Sainsbury Laboratory spring science meeting. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited presentation at The Sainsbury Laboratory, Norwich, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Was invited to give a presentation of my work on wheat rusts at the annual Sainsbury Lab retreat. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Invited presentation at University College Dublin |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | I gave a presentaiton to undergraduates and research scientists on the use of mutational genomics to isolate disease resistance genes. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Invited presentation at University of Nottingham |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | I was invited to give a presentation on my work at the University of Nottingham to share my latest results on rapid resistance gene discovery, cloning and deployment. This resulted in long discussions. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited presentation at the 8th Plant Genomics & Gene Editing Congress, Rotterdam, The Netherlands |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to present my work on rapid gene discovery and cloning, and generation advancement at the 8th Plant Genomics & Gene Editing Congress, Rotterdam, The Netherlands. |
| Year(s) Of Engagement Activity | 2020 |
| URL | http://www.global-engage.com/event/plant-genomics/ |
| Description | Invited presentation at the Australian National University, Canberra, Australia |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | I gave a presentation on cloning and stacking stem rust resistance genes in wheat. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Invited presentation at the Bill and Melinda Gates Foundation Grand Challenges Meeting in London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was asked to give a presentation on molecular breeding for durable disease resistance, including my work on speed breeding and speed cloning. The presentation sparked considerable interest and I was asked to chair two round table discussions on the topic where I answered many questions and was requested additional information. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://grandchallenges.org/videos |
| Description | Invited presentation at the Institute of Cereal Crop Research, Tel Aviv, Israel |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Gave a presentation on the use of genetic diversity from wild grasses to improve wheat disease resistance |
| Year(s) Of Engagement Activity | 2016 |
| Description | Invited presentation at the Ludwig Maximilian University of Munich |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | I was invited to give a presentation at the LMU about my work on rapid gene isolation and speed breeding in cereals. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Invited presentation at the Molecular Plant Microbes Interaction Meeting in Portland, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to give a presentation on my work on speed breeding and wheat rusts at the biennial congress on Molecular Plant-Microbe Interactions. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.ismpmi.org/Congress/2016/MeetingSchedule/Pages/default.aspx |
| Description | Invited presentation at the University of Copenhagen |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | I gave a presentation on the cloning of stem rust resistance genes from wheat and wild relatives and their potential use in transgenic wheat. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Invited presentation at the Wheat Durable Resistance Meeting, Minneapolis, USA |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to give a presentation at the Wheat Durable Resistance Meeting in Minneapolis, USA. The presentation lead to debate and request for additional information and collaboration. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.ag.ndsu.edu/wheatresistance |
| Description | Invited presentation at the Wheat Initiative Expert Working Group, Minneapolis, USA |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to join the wheat Expert Working Group on Control of Wheat Pathogens and Pests and deliver a presentation on available genomics and germplasm resources and what the community needs in this respect. The presentation lead to debate and requests for germplasm sharing with other labs. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.wheatinitiative.org/activities/expert-working-groups/control-wheat-pathogens-and-pests |
| Description | Invited presentation at the wheat breeding company KWS |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | I visited the wheat breeding company KWS at their Cambridge site and gave a presentation on how to use mutational genomics approaches to identify markers that can be used in breeding. The presentation sparked interest and generated significant debate. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Invited presentation by lab member PhD student Sreya Ghosh at Plant and Animal Genome Conference, 2020. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | My PhD student Sreya Ghosh was invited to present at PAG, 2020 in San Diego. This resulted in request for additional information and has led to the drafting of a patent application with the 2Blades Foundation. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Invited presentation: 2nd International Plant Genetics & Genomics Symposium, Assiut University, Egypt |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I gave a presentation on my wheat gene cloning work at an international meeting hosted by Assiut University, Egypt. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://figshare.com/articles/book/Book_of_Abstracts_IPGG_2020_docx/13079492 |
| Description | Invited presentation: Linné seminar, Swedish Agricultural University, Sweden |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | I was invited to give a presentation on the back of the presentation I gave at the Molecular Plant-Microbe Interactions conference in 2019. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Invited presentation: Novogene European User Forum |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was asked by the sequencing company Novogene, China, to give a presentation reporting on my use of high-throughput sequencing and bioinformatics to clone genes from crops. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://en.novogene.com/about/news/2020-novogene-european-user-forum/ |
| Description | JIC press release on AgRenSeq: "Rapid gene cloning technique will transform crop disease protection" |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | The press release was picked up by the national and international media and led to >10 requests for interviews from the press and media, including BBC Radio 4, The Times, Deutchlandfunk and others. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.jic.ac.uk/press-release/rapid-gene-cloning-technique-will-transform-crop-disease-protect... |
| Description | Keynote Speaker, Advances in Integrated Pest Management, Association of Applied Biologists, Harper Adams University, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to be a Keynote Speaker, at the meeting entitled Advances in Integrated Pest Management, Association of Applied Biologists, Harper Adams University, UK. This led to futher request to be involved in a responsive mode GCRF collaboration, which regretfully was not funded. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Keynote Speaker, German Plant Breeding Society, Wernigerode, Germany |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was the Keynote Speaker, German Plant Breeding Society, Wernigerode, Germany. This resulted in additional interest from a range of colleagues in academia and industry, including policy makers. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Laboratory News: "Fast Food" |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | I was interviewed by the online and print magazine Laboratory News about my new rapid gene cloning technology. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.popsci.com/crops-disease-resistant-genes |
| Description | Newspaper article in the Times: "Gene analysis speeds up race to beat cereal killer" |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | I was intereviewed by a reporter from The Times on our breakthrough in resistance gene cloning based on phenotyping sequence-configured diversity panels. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.thetimes.co.uk/article/gene-analysis-speeds-up-race-to-beat-cereal-killer-j2vsht83v |
| Description | Plant Genomics and Gene Editing Congress, Rotterdam, The Netherlands |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | I was invited to present at a Congress in Rotterdam. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Plenary Speaker, 4th International Conference on Plant Genetics, Genomics, Bioinformatics and Biotechnology, Almaty, Kazakhstan |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to present my work on speed cloning and speed breeding as a Plenary Speaker at the 4th International Conference on Plant Genetics, Genomics, Bioinformatics and Biotechnology, Almaty, Kazakhstan. This led to stimulating discussions and contributed to requests for further involvment. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Popular Science: "These genetic 'goggles' could help us engineer wildly resilient crops" |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | I was interviewed by the online magazine Popular Science about my work on rapid resistance gene cloning. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.popsci.com/crops-disease-resistant-genes |
| Description | Postdoc member Kumar Gaurav invited to present at Monogram Workshop, 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited presentation at the Monogram Workshop, 2019. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Presentation at 4th International Conference "Plant Biotic Stresses & Resistance Mechanisms", Vienna, Austria |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I presented my work at the 4th International Conference "Plant Biotic Stresses & Resistance Mechanisms", Vienna, Austria. |
| Year(s) Of Engagement Activity | 2020 |
| URL | http://viscea.org/plant-biotic-stresses-resistance-mechanisms-iv-february-19-20-2020/ |
| Description | Presentation at Institute of Genetics and Developmental Biology, Beijing, China |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to visit the Institute of Genetics and Developmental Biology, Beijing, China and present my work on speed cloning and speed breeding. This has led to follow up requests for further visits, collaboration, and applicaiton for joint funding opportunities. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Presentation at International Wheat Conference, Saskatoon, Canada |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | MINING A SEQUENCE-CONFIGURED WILD WHEAT DIVERSITY PANEL FOR GENES REGULATING ENVIRONMENTAL RESPONSE USING ASSOCIATION GENETICS |
| Year(s) Of Engagement Activity | 2019 |
| Description | Presentation at John Innes Centre Wheat Breeders Day 2019 |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | We presented a talk on "Mining wild wheat diversity for disease resistance". This sparked questions and discussions. I have been asked to visit BASF in Gent, Belgium to discuss potential collaboration. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Presentation at Nanjing Agricultural University, China |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to Nanjing Agricultural University, China where I gave a presentation on my work on speed cloning and speed breeding. I was invited to participate in further collaborations based on this visit. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Presentation at Science Innovation Showcase, JIC, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | I was invited to present at the Science Innovation Showcase, JIC, UK. This has led to requests for further information and ongoing disussions with inustrial partners for collaboration / contract research. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Presentation at Tel Aviv University, Israel |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to present my work on speed breeding and speed cloning at Tel Aviv University, Israel. This led to further discussions and resulted in an active collaboration and exchange of germplasm. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Presentation at the Borlaug Global Rust Initiative Workshop by Amber Hafeez |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | My PhD student Amber N. Hafeez gave a presentation on the concept of a "Resistance Gene Atlas" for wheat. It was well received and we have been asked for further engagement with BGRI, wheat breeders, and researchers. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.youtube.com/watch?v=wtfOWzqoHfU&feature=youtu.be |
| Description | Presentation at the Borlaug Global Rust Initiative Workshop by Kumar Gaurav |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | My Postdoc Kumar Gaurav was invited to present our work, entitled: "Exploiting diversity in the bread wheat D-genome progenitor" from the Open Wild Wheat Consortium (www.openwildwheat.org). The presentation was well received as evidenced by the questions and ensuing Twitter activity. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://bgri.cornell.edu/2020-bgri-technical-workshop-day-2/ |
| Description | Presentation at the Borlaug Global Rust Initiative Workshop by Paul Nicholson |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Our close collaborator, Paul Nicholson, was called upon to present our work on cloning wheat blast resistance genes at the BGRI Technical Workshop. The presentation was well received and the video, which was uploaded to Facebook on 15 December, has since been viewed more than 200 times. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.facebook.com/globalrust/videos/bgri-2020-technical-workshop-identification-of-wheat-blas... |
| Description | Presentation at the Borlaug Global Rust Initiative Workshop by Sanu Arora |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | My Postdoc Sanu Arora was invited to present our work on wheat gene cloning technologies at the BGRI meeting. The presentation was very well received as evidenced by the questions and ensuing Twitter activity. The video of the presentation been viewed more than 500 times on Facebook and ~150 times on Youtube. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.youtube.com/watch?v=PuDKb5ZeWjU |
| Description | Presentation to Appolinaire Dijkeng and Jacob Mignouna, BecA |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I gave a presentation to Appolinaire Dijkeng and Jacob Mignouna from the BecA-ILRI Hub in Nairobi, Kenya. This was part of ongoing discussions and collaborative work between JIC and BecA-ILRI. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Presentation to Elsoms Seeds, Spalding, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to present my work on speed breeding and resistance gene cloning to Elsoms Seeds, Lincolnshire, and to troubleshoot their LED lighting in the glasshouse. This has since resulted in further interactions and dicussions. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Presentation to Joe Cerrell & James Birch, BMGF |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | Joe Cerrell & James Birch frin the Bill and Melinda Gates Foundation came to visit JIC and I was called upon to present my work on wheat stem rust and the solution we are working on to try to mitigate this problem for small holder farmers in Africa. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Presentation to KWS, Einbech, Germany |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | I was invited to present my work on speed cloning and speed breeding at KWS, Einbech, Germany. KWS are currently considering how our enabling technologies could be integrated in one of their own crop breeding programmes and how we may collaborate to achieve this. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Presentation to delegation from Elsoms Seeds, Lincolnshire, UK |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | I invited 8 delegates from Elsoms Seeds to visit JIC for some bespoke presentations from my group and a colleauge, and for an inspection of our speed breeding facilities. This has helped cement a relationship that now stretches back more than one year. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Science Collaboration Agritech, Aquaculture and Food Safety Forum, Muscat, Sultanate of Oman |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to present at the Science Collaboration Agritech, Aquaculture and Food Safety Forum, Muscat, Sultanate of Oman. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Short presentation to Eric Danquah, WACCI, Ghana |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was called upon to give a presentation to a visiting dignitary, Eric Danquah from the WACCI, Ghana. This lead to a lively discussion and exhange of ideas and request for further collaboration. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Teleconference discussion with Syngenta |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Participated in a teleconference with Syngenta with participation from China, UK and USA. Follow-on discussions are ongoing. |
| Year(s) Of Engagement Activity | 2018 |
| Description | The Sainsbury Laboratory Annual Retreat |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | I presented my yearly update to The Sainsbury Laboratory as part of my Adjunct Affiliation with this institution. |
| Year(s) Of Engagement Activity | 2018 |
| Description | The Sainsbury Laboratory Retreat 2017, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was invited to present my work on R gene cloning and speed breeding at The Sainsbury Laboratory 2017 retreat. This sparked questions and discussions and has since contributed to further collaboration with colleagues in TSL. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Two invited presentations at Next-generation wheat breeders workshop, University of Saskatchewan, Canada |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Myself and my postdoc, Sanu Arora, were invited to present on our enabling technology for rapid cloning of disease resistance genes by association genetics. This sparked a lot of interest and led to an invitation to present again at the International Wheat Congress, Saskatchewan, Canada, the following week. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://2019iwc.ca/pre-conference-workshop/ |
| Description | University of Maryland, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | I was called upon to speak in the departmental seminar series by a collaborator form University of Maryland, USA. |
| Year(s) Of Engagement Activity | 2020 |
| Description | University of Zurich, Switzerland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | I was called upon by one of my collaborators to present my work at the University of Zurich |
| Year(s) Of Engagement Activity | 2020 |
| Description | Wheat molecular genomics workshop in Cairo, Egypt |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | In collaboration with Dr Ahmed Elkot of the Agricultural Research Centre (ARC) in Cairo, Egypt, we organised a workshop for wheat researchers and breeders. Approximately 50 scientists attended including the Minister of Agriculture and the President of the ARC (which employs ~60,000 staff). The event was a great success and covered in the national media in Egypt. The ARC staff were very honoured that the Minister of Agriculture attended. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.facebook.com/526865257491839/posts/1170288249816200/ |
| Description | Workshop at BecA-ILRI, Kenya on Molecular Breeding in Small Grain Cereals |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | I co-organised and taught a short 4-day course on molecular breeding in small grain cereals (wheat, barley and teff) for African scientist and breeders. Participants came from Ethiopia (~12), Kenya, Uganda, Tanzania, Madagascar, Nigeria and Burundi. The course was well received, led to requests for additional information, request to repeat the course the following year, and the possibility of a new strategically interesting collaboration with young career wheat scientist from Ethiopia. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://hpc.ilri.cgiar.org/beca/training/jic_beca_2016/index.html |
| Description | Workshop on Scientific Softskills, Punjab Agricultural University, Ludhiana, India |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | I organised and presented, with colleagues, a workshop on scientific soft skills to early career scientists primarily from India, but also from the UK, Tunisia and Iran. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Workshop on scientific communication for early career scientists in Pwani, Kenya |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Along with my colleague Prof. Cristobal Uauy, I was invited to give a two-day course on scientifict communication to early career scientists from across Sub Saharan Africa as part of the ACACIA AfriPlantSciences course. The course involved practical sessions on scientific writing, oral presentation, CV + cover letter, job interview, and applying for a travel award. The participants responded very positively to the course. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://acaciaafrica.org/afriplantsci/ |
| Description | Young Anglia Grows: LEP agri-tech 6th form taster course |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Myself, members of my lab, and a few colleagues entertained a group of ~10 year 12 pupils (top end of ability range) sourced by recommendations from Norfolk heads of biology. The day included a session on wheat diseases (formal lecture), a practical on using microscopes to observe wheat infected by stripe rust, a tour of the John Innes Centre and TGAC facilities, and a hands-on bioinformatics practical. |
| Year(s) Of Engagement Activity | 2015 |
| URL | http://www.newanglia.co.uk/ |
| Description | Youtube video: "What is AgRenSeq" |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Ruby O'Grady in the JIC External Communications Team generated an animation to explain the meaning of the acronym "AgRenSeq". |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.youtube.com/watch?v=xefrjg5Y_Ug&t=6s |