NMR Facilities for the School of Chemistry of the University of Manchester
Lead Research Organisation:
University of Manchester
Department Name: Chemistry
Abstract
Nuclear magnetic resonance (NMR) is our main way of identifying new chemical substances, and is an essential tool for modern chemistry. Provision of new NMR equipment will support research at the forefront of modern chemistry in diverse areas such as: development of NMR techniques (Morris); synthetic organic chemistry (Thomas, Clayden, Sutherland, Dixon, Procter); synthetic inorganic chemistry (Winpenny, Collison, Heath, McInnes, Faulkner, Coe); organic materials (Turner, Yeates, Skabara); mesoporous materials (Anderson). Goals include making the smallest possible magnets - individual molecules in which many electrons line up in parallel - for storage and processing of information; new NMR methods for analysing mixtures, for detecting brain damage in stroke patients, and for studying biomolecules; new synthetic organic chemistry designed to give us, amongst many other things, improved antibiotics and other drugs; studies of the molecular origin of life, and of the ways in which enzymes speed chemical reactions; designing and making new porous inorganic materials for fuel cells and environmentally-friendly catalysts; making molecules whose properties are changed by light, to make more efficient fuel cells; and measuring NMR spectra in solids to learn about the active sites in solid catalysts, gas sensors, and systems for cleaning waste water and nuclear effluent.
Publications
Allen J
(2008)
On the use of the modified Julia olefination for bryostatin synthesis
in Tetrahedron Letters
Haouas M
(2009)
29 Si NMR Relaxation of Silicated Nanoparticles in Tetraethoxysilane-Tetrapropylammonium Hydroxide-Water System (TEOS-TPAOH-H 2 O)
in The Journal of Physical Chemistry C
Nilsson M
(2007)
Pure shift proton DOSY: diffusion-ordered 1H spectra without multiplet structure.
in Chemical communications (Cambridge, England)
Powner MW
(2009)
Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions.
in Nature
Spring AM
(2009)
MEH-PPV by microwave assisted ring-opening metathesis polymerisation.
in Chemical communications (Cambridge, England)
Description | Nuclear magnetic resonance (NMR) is our main way of identifying new chemical substances, and is an essential tool for modern chemistry. Provision of new NMR equipment has supported research at the forefront of modern chemistry in diverse areas such as: development of NMR techniques (Morris); synthetic organic chemistry (Thomas, Clayden, Sutherland, Dixon, Procter); synthetic inorganic chemistry (Winpenny, Collison, Heath, McInnes, Coe); organic materials (Turner, Yeates); mesoporous materials (Anderson). Achievements include new NMR methods for analysing mixtures; progress in the development of single molecule magnets; new synthetic organic chemistry designed to give us, amongst many other things, improved antibiotics and other drugs; new insights into the origin of life, through prebiotic chemistry (reported on the front pages of The Independent and the New York Times, and in other publications across the world); chemical routes to new materials such as polymers and nanoparticles; new applications of lipid vesicles, analogues of living cells; new methods for controlling chemistry over long distances; new methods for making organic transistors; and new insights into how crystals grow. Over 200 papers were published during the grant period describing work that made direct use of the NMR facilities provided. |
Exploitation Route | Too numerous to list, with over 40 academic staff involved and a large number of individual projects. |
Sectors | Chemicals,Energy,Environment,Pharmaceuticals and Medical Biotechnology |
URL | http://www.chemistry.manchester.ac.uk/our-research/ |
Title | Varian Licence |
Description | License to Varian Inc for software for diffusion-ordered NMR spectroscopy. |
IP Reference | |
Protection | Copyrighted (e.g. software) |
Year Protection Granted | |
Licensed | Yes |