Generation of singlet oxygen mediated by silicon nanoassemblies for novel organic catalytic reactions

Lead Research Organisation: University of Warwick
Department Name: Sch of Engineering

Abstract

The proposed project is in the area of sustainable chemical technology and is ultimately aimed at developing a novel generic approach towards clean organic synthesis. The methodology, exploiting reactivity of singlet oxygen in diastereo- and enantioselective reactions, will be developed. The proposed methodology is, uniquely, based on the synergy between recently discovered highly effective generation of 1O2, mediated by silicon nanocrystals assemblies, and the novel reaction engineering concept of multifunctional structured reactors with imbedded light-emitting diodes. The proposal identifies the significant potential of adopting new concepts of process intensification (via non-thermal activation and miniaturisation, i.e. enhanced mass and heat transfer) and functional nanomaterials in clean organic catalysis. Most significantly, the proposal addresses the underdevelopments in the areas of clean organic synthesis and non-thermal activation of molecules.

Publications

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Related Projects

Project Reference Relationship Related To Start End Award Value
EP/E012183/1 01/02/2007 31/08/2009 £270,847
EP/E012183/2 Transfer EP/E012183/1 01/11/2009 30/09/2010 £49,198
 
Description In this project we studied a new way of activating molecules, using light, instead of heat. This method is more efficient in terms of overall energy demand for chemical processes when wavelength-specific molecular activation is feasible. The project has investigated a large number of possible reactor configurations and a generic model for a continuous flow photochemical reactor was developed. What the model had shown is the broad optimum as a function of reactor depth, which indicated that there is a significant flexibility in the design of such reactor systems for specific applications. This was the first such model available for photochemical reactors.
Exploitation Route The model we developed is generic and could be applied to many specific situations. We have also shown critical issues with different reactor technologies. These will be directly adoptable by all researchers and industry working in the area of photochemistry.
Sectors Chemicals,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology