A study into the mechanism and utility of single electron reduction in organic synthesis

Lead Research Organisation: University of Oxford
Department Name: Oxford Chemistry


This proposal seeks to develop a new and more efficient way to prepare complex organic molecules. Our efforts will focus on the addition of electrons to a variety of organic compounds because this process can transform them into especially useful new derivatives.We aim to use an electron shuttle to transfer electrons from the surface of a metal to the organic compound in question; an understanding of the way that this works is of paramount importance if we are to optimise and harness it. By using a combination of electochemistry and preparative chemistry, we aim to delve deep into the mechanism of a complex process and emerge with a range of new reducing conditions.This will result in the development of selective new reduction reactions, which is important to chemical industry as well as academia because it enables valuable organic compounds to be prepared quickly and efficiently with minimisation of cost and waste produced.
Description Information of the details of electron transfer to enable selective synthesis of complex molecules.
Exploitation Route Reactions used by others to make complex organic molecules
Sectors Pharmaceuticals and Medical Biotechnology

Description Used to make complex organic molecules.
First Year Of Impact 2007
Sector Pharmaceuticals and Medical Biotechnology
Impact Types Economic