Science Bridges: Bradford-China Programme for Pharmaceutical Sciences and Medical Technology

Lead Research Organisation: University of Bradford
Department Name: The Registrar and Secretary

Abstract

The programme focusses on the development of products aligned with the strategic priorities of both the Chinese and British governments in their respective health delivery policies and associated industries (e.g. diabetes, infection control, traditional Chinese medicine (TCM) and medical devices). Its overall purpose will be to provide effective solutions to these needs. Outcomes are expected to be new therapies, enhanced biomaterials and medical devices, and the application and validation of processes to accelerate the discovery and commercialization of new drugs/ medical devices. We have two major Themes: Pharmaceutical Sciences and Medical Technology. In the first Theme, emphasis will be placed on Traditional Chinese Medicine, and in the second Theme, materials for biomedical applications, and related devices. All the programme activities will involve Bradford-based teams (strengthened by other UK universities, Health Services and companies whenever appropriate) and identified leading Chinese universities and organisations. Building on existing strong links between UoB and Chinese academia, we aim to accelerate product invention, design, and development through stimulating open innovation between the UK and China, for Pharmaceutical Sciences - particularly drug discovery and delivery - and Medical Technology, meeting aligned needs of the UK and China. This will be addressed by three main activities: (i) an Open Innovation project scheme to develop prototypes and products, (ii) reciprocal training programmes based on the two Themes, and (iii) developing state-of-the-art knowledge and commercial networks. We will also provide means for managing exploitation of the outcomes.Each Theme is associated with leading research and KT areas in Bradford: Pharmaceutical Sciences [pharmaceutics, bioimaging (www.ipi.ac.uk) and drug discovery & development (www.cancer.brad.ac.uk)] and Advanced Materials Engineering [polymer engineering (www.polyeng.com), part of the internationally leading Polymer IRC]. Over the past 2 years these groups have developed an exciting third area of combined research, Healthcare Technologies - including a recent joint Chair in Pharmaceutical Engineering Science, and collaborative research and commercialisation projects (see Track Record). All three R&KT areas have extensive but developing (and sometimes connected) links with leading Chinese Universities and co-operative organisations such as Medilink Y&H Ltd, which is taking a major lead on behalf of UKTI on health technology partnerships with China, to help regional high technology companies, including SMEs, develop opportunities and products.

Publications

10 25 50
 
Description The Bradford RCUK Science Bridges China programme (www.sciencebridgeschina.com) has formed links with leading Chinese academics in advanced materials (particularly polymer-related) for healthcare, and in pharmaceuticals, including drug discovery and drug delivery. We have established collaborations with over 20 leading Chinese groups, and have regularly involved academics from Bradford, Sheffield, Durham, Leeds and York, plus Warwick in our meetings. We have run nine major Research Workshops (alternating between the UK and China), and six open innovation workshops funded by Chinese local governments (Chuzhou, Guangzhou) and recently, Yorkshire Cancer Research.
The University of Bradford established a Joint International Laboratory for Polymer Microprocessing with Sichuan University in July 2010. We formed the UK-China Advanced Materials Research Institute (www.ukchina-amri.com) in April 2012 - we have a strongly developed community, with research exchanges, joint publications, joint IP, joint international grants (including NSFC, MOST, MRC-MOST, EPSRC),and interactions with industry and hospitals, both in the UK and China. The Joint laboratory with Changchun CIACCAS for Polymer Process Physics was opened in September 2015 and with Beijing University of Chemical Technology, on Soft Matter Technologies, in Dec 2016. The EPSRC MeDe CIM was included in our ongoing international meetings, and involved in the growing programme of Researcher Exchanges. A booklet giving fuller details of the programme is available on the web sites: www.sciencebridgeschina.com and www.ukchina-amri.com.
Exploitation Route We have an open collaboration - so other academic, industrial and hospital groups are being encouraged to join our community. Our Science Bridges China model is highly regarded in both the UK and China - it was jointly presented to the Minister for Science & the Universities in Chengdu in Dec 2013 and recognised as a most successful model, to be built upon. Our community continues and is exploring further ways of developing research collaborations. We have established a database of researchers in advanced materials for healthcare (see www.ukchina-amri.com)
Sectors Chemicals,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology

URL http://www.sciencebridgeschina.com
 
Description The Bradford RCUK Science Bridges China programme (www.sciencebridgeschina.com) has had major impact on UK links with leading Chinese academics in advanced materials (particularly polymer-related) for healthcare, and in pharmaceuticals, including drug discovery and drug delivery. We have established collaborations with over 20 leading Chinese groups, and have regularly involved academics from Bradford, Sheffield, Durham, Leeds and York, plus Warwick in our meetings. We have run six major Research Workshops (alternating between the UK and China), and six open innovation workshops funded by Chinese local governments (Chuzhou, Guangzhou) and recently, Yorkshire Cancer Research. The University of Bradford established a Joint International Laboratory for Polymer Microprocessing with Sichuan University in July 2010. We formed the UK-China Advanced Materials Research Institute (www.ukchina-amri.com) in April 2012 - we have a strongly developed community, with research exchanges, joint publications, joint IP, joint international grants (including NSFC, MOST, MRC-MOST, EPSRC) and interactions with industry and hospitals, both in the UK and China. A booklet giving fuller details of the programme is available on the web sites: www.sciencebridgeschina.com and www.ukchina-amri.com. This shows the visibility of the platform, with clear recognition of our activities by Uk and Chinese government agencies, plus a range of international research cooperation awards.Three Joint international Research Laboratories have now been formed, with Sichuan University, Changchun CIACCAS and Beijing University of Chemical Technology. Prof Coates has been honoured with the Sichuan Tianfu Friendship Award (2015), the Sichuan Province International Science and Technology Cooperation Award (2016), and the highest honour for foreign scientists, the 2017 International Science and Technology Co-operation Award of the People's Republic of China, presented by President Xi Jinping and the full leadership team, Beijing Jan 2018.
First Year Of Impact 2012
Sector Healthcare,Pharmaceuticals and Medical Biotechnology
Impact Types Cultural,Societal,Economic

 
Description British Council Newton Researcher Links 'Healthcare Technologies for Aging Populations'
Amount £24,000 (GBP)
Funding ID 227337704 
Organisation British Council 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2016 
End 01/2017
 
Description EPSRC - Global Engagements
Amount £499,000 (GBP)
Funding ID EP/K004204/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start 03/2012 
End 03/2013
 
Description EPSRC - Global Engagements
Amount £499,989 (GBP)
Funding ID EP/K004204/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start 04/2012 
End 03/2013
 
Description Medical Research Council
Amount £40,000 (GBP)
Funding ID Stem cell initiative 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2012 
End 03/2013
 
Description Ministry of Education of China
Amount £100,000 (GBP)
Organisation Ministry of Education of the People's Republic of China 
Sector Public
Country China
Start 06/2010 
End 06/2015
 
Description Ministry of Education of China
Amount £100,000 (GBP)
Organisation Ministry of Education of the People's Republic of China 
Sector Public
Country China
Start 07/2010 
End 06/2015
 
Description Ministry of Science and Technology (MOST
Amount £200,000 (GBP)
Organisation Ministry of Science and Technology 
Sector Public
Country China
Start 06/2011 
End 06/2012
 
Description Ministry of Science and Technology (MOST
Amount £200,000 (GBP)
Organisation Ministry of Science and Technology 
Sector Public
Country China
Start 05/2011 
End 12/2012
 
Description Ministry of Science and Technology (MOST
Amount £200,000 (GBP)
Funding ID S2010GR0920 
Organisation Ministry of Science and Technology 
Sector Public
Country China
Start 05/2010 
End 12/2012
 
Description Ministry of Science and Technology (MOST
Amount £200,000 (GBP)
Funding ID 2010DFA32420 
Organisation Ministry of Science and Technology 
Sector Public
Country China
Start 05/2010 
End 12/2012
 
Description Ministry of Science and Technology (MOST
Amount £200,000 (GBP)
Funding ID S2010GR0920 
Organisation Ministry of Science and Technology 
Sector Public
Country China
Start 06/2010 
End 06/2012
 
Description Ministry of Science and Technology (MOST
Amount £200,000 (GBP)
Funding ID 2010DFA32420 
Organisation Ministry of Science and Technology 
Sector Public
Country China
Start 06/2010 
End 06/2012
 
Description Natural Science Foundation of China
Amount £160,000 (GBP)
Funding ID 51010004 
Organisation National Science Foundation China 
Sector Public
Country China
Start 06/2011 
End 06/2013
 
Description Natural Science Foundation of China
Amount £160,000 (GBP)
Funding ID 51010004 
Organisation National Science Foundation China 
Sector Public
Country China
Start 01/2011 
End 12/2013
 
Description Royal Academy of Engineering Fellowship
Amount £20,000 (GBP)
Funding ID 1314RECI013 
Organisation Royal Academy of Engineering 
Sector Learned Society
Country United Kingdom
Start 07/2014 
End 05/2015
 
Description Royal Society Newton Advanced Fellowship
Amount £111,000 (GBP)
Funding ID NA150222 
Organisation The Royal Society 
Sector Academic/University
Country United Kingdom
Start 09/2015 
End 08/2018
 
Description White Rose University Consortium
Amount £50,000 (GBP)
Organisation White Rose University Consortium 
Sector Academic/University
Country United Kingdom
Start 01/2012 
End 04/2016
 
Description White Rose University Consortium
Amount £50,000 (GBP)
Organisation White Rose University Consortium 
Sector Academic/University
Country United Kingdom
Start 01/2012 
End 04/2016
 
Description Yorkshire Cancer Research
Amount £250,000 (GBP)
Organisation Yorkshire Cancer Research 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2012 
End 05/2014
 
Description Yorkshire Cancer Research
Amount £250,000 (GBP)
Organisation Yorkshire Cancer Research 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2012 
End 05/2014
 
Title UK-China Advanced Materials Research Institute 
Description A database of capability of individual researchers in advanced materials for healthcare, particularly related to polymers, but including aspects of drug delivery and drug discovery, from the Science Bridges China and Global Engagements platform of research collaborations. 
Type Of Material Database/Collection of data 
Year Produced 2012 
Provided To Others? Yes  
Impact building a community of researchers across the UK and China 
URL http://www.ukchina-amri.com
 
Description Aterius oriented polymer stents 
Organisation Arterius Limited
Country United Kingdom 
Sector Private 
PI Contribution precision small scale die drawing of bioresorbable polymers to make oriented tubes, used to laser cut stents. Shared IP with Arterius
Collaborator Contribution Original approach to us from Arterius, IP (shared), for use of our oriented polymer routes.
Impact the only British drug eluting, resorbable stent - currently close to commercialisation, in trials. Combination of engineering sciences and pharmaceutical science.
Start Year 2009
 
Description Joint International Laboratory for Polymer Micro Processing 
Organisation Sichuan University
Country China 
Sector Academic/University 
PI Contribution Establishment of a micro moulding facility in Sichuan, to mirror the (more extensive) facilities in Bradford, to develop further our collaborative research. Joint IP for conducting polymer products.
Collaborator Contribution Materials engineering expertise, including polymer nano composite products, especially for electrically conducting products. Joint IP for conducting polymer products.
Impact Joint publications. Joint IP
Start Year 2010
 
Description Joint International Laboratory for Soft Matter Technologies 
Organisation Beijing University of Technology
Department College of Environmental and Energy Engineering
Country China 
Sector Academic/University 
PI Contribution Hosting Researcher Exchanges leading to joint publications; advisory role with respect to development of particular technologies
Collaborator Contribution sending researchers to our laboratory, leading to joint publications; Support (from Prof Zhang Liqun) for meetings with the Ministry of Science & Technology in Beijing
Impact joint publications
Start Year 2016
 
Description Joint Laboratory for Polymer Process Physics 
Organisation Changchun Institute of Applied Chemistry
Country China 
Sector Academic/University 
PI Contribution Royal Society Newton award, following Science Bridges China researcher exchanges (two way)
Collaborator Contribution High quality x-ray analysis of oriented polymers
Impact Journal papers (Macromolecules)
Start Year 2015
 
Description Sinopec solid phase orientation project 
Organisation Sinopec Group
Country China 
Sector Private 
PI Contribution research skills and facilities for solid phase orientation processing of polymers
Collaborator Contribution materials manipulation and supply
Impact confidential to company
Start Year 2013
 
Description Smith & Nephew programmes 
Organisation Smith and Nephew
Country United Kingdom 
Sector Private 
PI Contribution solid phase processing of polymers and development of shape memory materials and products for tissue fixations. Joint IP on these materials and products.
Collaborator Contribution Development of shape memory materials and products for tissue fixations. Joint IP on these materials and products. Clinical challenges and assistance.
Impact extensive knowledge on shape memory materials for potential products in fixations. Combination of physics, mechanical engineering, biomedical engineering, biomaterials, medical technology.
 
Title Methods to improve the electrical conductivity for moulded plastic parts 
Description micromoulded polyurethane with carbon nanotubes has high levels of conductivity after post-processing annealing; potential use in medical devices 
IP Reference WO 2012/089998 A2 PCT/GB2011/001775 
Protection Patent granted
Year Protection Granted 2011
Licensed Yes
Impact micromoulded polyurethane with carbon nanotubes has high levels of conductivity after post-processing annealing has potential use in medical devices
 
Description Article in China Daily, 9 Jan 2018 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact China Daily article in Beijing, after the Award Ceremony for the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, presented by President Xi Jinping and other leaders. This is the top award in China for foreigners. Prof Phil Coates was one of the seven foreigners honoured with the award. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://www.chinadaily.com.cn/a/201801/09/WS5a53fa36a31008cf16da5d10.html
 
Description British Council Newton Researcher Links Workshop for Early Career Researchers 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Study participants or study members
Results and Impact 13 UK-China Researcher Exchanges (funded separately from the Workshop) are being set up to run before Sep 2017
Year(s) Of Engagement Activity 2016
URL http://www.ukchina-amri.com
 
Description CCTV longer interview 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact CCTV mainstream news - my experience of the Golden Era through my research collaborations, and a celebration of the top award in China to a foreign scientist.
Year(s) Of Engagement Activity 2018
URL http://www.ukchina-amri.com
 
Description China Daily Europe article on top award in China made to Prof Phil Coates; 12 Jan 2018 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact China Daily article in Europe, after the Award Ceremony in Beijing for the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, presented by President Xi Jinping and other leaders. This is the top award in China for foreigners. Prof Phil Coates was one of the seven foreigners honoured with the award. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://europe.chinadaily.com.cn/a/201801/12/WS5a57acafa3102c394518ea1e.html
 
Description Chinese International Award 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Articles in China Daily - in English - in the UK and China; and other Chinese national newspapers concerning the Award to Prof Coates of the International Science & Technology Cooperation Award, the top award in China for a foreign scientist.
Year(s) Of Engagement Activity 2018
URL http://www.ukchina-amri.com
 
Description ECNS China article on top Chinese Award to Prof Phil Coates, 12 Jan 2018 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact ECNS article in Beijing, after the Award Ceremony for the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, presented by President Xi Jinping and other leaders. This is the top award in China for foreigners. Prof Phil Coates was one of the seven foreigners honoured with the award. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://www.ecns.cn/business/2018/01-12/288042.shtml
 
Description Interview for CCTV 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Interview of 3 leading UK people for opinion on developments in China, based on our experience - in my case research collaborations
Year(s) Of Engagement Activity 2017
 
Description SPE International Award in Plastics News (USA based publication, also in Europe and Asia) 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Announcement of the Society of Plastics Engineers Intenational award, the top award of the SPE, to Prof Phil Coates. This increases the visibility of the UK in the polymer engineering research area, where Prof Coates directs the world-leading Polymer IRC. The Award will be presented in May 2018 at the SPE major international conference, with a Plenary lecture.
Year(s) Of Engagement Activity 2018
URL http://www.plasticsnews.com/article/20180222/NEWS/180229963/spe-names-annual-award-winners-antec-spe...
 
Description Sichuan University article following top China Award to Prof Phil Coates in Jan 2018 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Sichuan University article, after the Award Ceremony for the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, presented by President Xi Jinping and other leaders. This is the top award in China for foreigners. Prof Phil Coates was one of the seven foreigners honoured with the award. He is an Honorary Professor and High End Foreign Professor of Sichuan University, who are one of the main collaborators with Bradford and others in our ongoing Science Bridges China programme. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://www.scu.edu.cn/en/news/webinfo/2018/01/1514127424326967.htm
 
Description Xinhua article on China Award for Prof Coates 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Xinhua press article in Beijing, after the Award Ceremony for the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, presented by President Xi Jinping and other leaders. This is the top award in China for foreigners. Prof Phil Coates was one of the seven foreigners honoured with the award. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://www.xinhuanet.com/english/2018-01/08/c_136880680_10.htm
 
Description article in China Daily, 19 Jan 2018 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Interview of Prof Coates by China Daily in Beijing, after he received the International Science & Technology Cooperation Award of the People's Republic of China, Jan 2018, from President Xi Jinping and other leaders. This is the top award in China for foreigners. It increased the visibility of the UK in China (Prof Coates was only the sixth UK citizen to receive this award in over 20 years) and has given further momentum to the UK-China advanced materials for healthcare research community which he founded, and continues to lead, from the EPSRC-funded Science Bridges China platform. This top Award has very great significance for our key Chinese collaborators, and will promote and strengthen our research collaborations.
Year(s) Of Engagement Activity 2018
URL http://www.chinadaily.com.cn/a/201801/19/WS5a61c69fa3106e7dcc13562d.html