Imaging cellular function on the nanoscale

Lead Research Organisation: Imperial College London
Department Name: Dept of Medicine

Abstract

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Publications

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Actis P (2014) Tailoring Nanoprobes for Single-Cell Surgery in Biophysical Journal

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Actis Paolo (2014) Tailoring Nanoprobes for Single-Cell Surgery in BIOPHYSICAL JOURNAL

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Joensson P. (2013) Molecular nanomechanics and local stimulus of individual biomolecules on the surface of cells in EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

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Klenerman D (2013) Imaging the cell surface and its organization down to the level of single molecules. in Philosophical transactions of the Royal Society of London. Series B, Biological sciences

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Leo-Macias Alejandra (2015) Nanoscale Visualization of Functional Adhesion/Excitability Nodes at the Intercalated Disc. in JOURNAL OF GENERAL PHYSIOLOGY

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Lopez-Cordoba Ainara (2015) SICM-Based Nanodelivery System for Local TRPV1 Stimulation in BIOPHYSICAL JOURNAL

 
Description We have developed a method to map the mechanical properties of the cell at the nanoscale and locally devilver reagents to defined positions on the cell.
Exploitation Route These methods can be used to map receptors and mechanosensitive ion channels.
Sectors Healthcare,Pharmaceuticals and Medical Biotechnology