Parallel electrophysiological characterization of sodium channels
Lead Research Organisation:
Birkbeck, University of London
Department Name: Biological Sciences
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Publications
D'Avanzo N
(2013)
Differential Lipid Dependence of Function of Bacterial Sodium Channel Homologues
in Biophysical Journal
D'Avanzo N
(2013)
Differential lipid dependence of the function of bacterial sodium channels.
in PloS one
Kalsi S
(2014)
Shaped apertures in photoresist films enhance the lifetime and mechanical stability of suspended lipid bilayers.
in Biophysical journal
Lopes JL
(2014)
Deconstructing the DGAT1 enzyme: Binding sites and substrate interactions.
in Biochimica et biophysica acta
Powl AM
(2012)
Transmembrane and extramembrane contributions to membrane protein thermal stability: studies with the NaChBac sodium channel.
in Biochimica et biophysica acta
Powl AM
(2010)
Synchrotron radiation circular dichroism spectroscopy-defined structure of the C-terminal domain of NaChBac and its role in channel assembly.
in Proceedings of the National Academy of Sciences of the United States of America
Saha SC
(2015)
Screening ion-channel ligand interactions with passive pumping in a microfluidic bilayer lipid membrane chip.
in Biomicrofluidics
Saha SC
(2015)
Characterization of the Prokaryotic Sodium Channel NavSp Pore with a Microfluidic Bilayer Platform.
in PloS one
Sait LG
(2020)
Cannabidiol interactions with voltage-gated sodium channels.
in eLife
| Description | collaborated on developing devices for electrophysiological characterisations |
| Exploitation Route | further development of devices or knowledge of channel function from our publications |
| Sectors | Pharmaceuticals and Medical Biotechnology |
| Title | development of new devices for electrophysiological characterisation of ion channels |
| Description | devices for measuring ion channel conductance done in collaboration with partners at Southampton |
| Type Of Material | Technology assay or reagent |
| Provided To Others? | No |
| Impact | new device |
| Description | collaborative partnership with Southampton university (linked grant holder) |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | team effort: our group made and measured the biological test systems for the devices constructed at Southampton |
| Collaborator Contribution | made and measured the biological test system |
| Impact | publications PhD student (not yet completed) |
| Start Year | 2010 |
| Description | annual talks for the public |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | UCL Science Centre Friday Evening Discourses and Birkbeck SET Talks for the Public talks on science for the public (5th, 6th form, and public) annually and lecture/tour at the Wellcome Collection talks no actual impacts realised to date |
| Year(s) Of Engagement Activity | 2006,2007,2008,2009,2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020 |