EPSRC-Royal Society fellowship engagement (2012): From Spectra to Sampling - Functional Analysis meets Applied Harmonic Analysis

Lead Research Organisation: University of Cambridge
Department Name: Applied Maths and Theoretical Physics

Abstract

Please refer to attached Royal Society application

Planned Impact

Please refer to attached Royal Society application

Publications

10 25 50
 
Description The main discovery of the project has been a mathematical theory to optimise sampling strategies used in medical imaging (e.g. MRI) that allows for speedup of the acquisition time as well as resolution enhancing of the images. This allows for substantial time reduction in medical imaging as well as better image quality, which again may lead to more accurate diagnosis of patients.
Exploitation Route The mathematical theory is developed for a technique called compressed sensing. This techniques was in 2017 approved by the US Food and Drug Administration for use in MRI. As a result, all the major producers of MRI machines have implemented this technique in their machines.
Sectors Healthcare

 
Description Siemens, one of the largest manufacturers of medical imaging equipments, has already implemented the methods provided by this research project on their MRI machines. As a result of the US Food and Drug Administration's approval of compressed sensing for commercial use in MRI machines, these techniques are now universally implemented across all manufacturers. Our theoretical development provides the understanding of why and how this works, and allows for optimal use.
Sector Healthcare
Impact Types Societal,Economic

 
Description Resolution enhancing in MRI 
Organisation University of Cambridge
Department Department of Radiology
Country United Kingdom 
Sector Academic/University 
PI Contribution We have developed a mathematical theory that shows how one can enhance resolution in Magnetic Resonance Imaging. We have also implemented this in software that can be readily used for practitioners.
Collaborator Contribution Our partners at the radiology department have provided us with data and expertise on MRI machines in order to optimize our method for use in practice. Our partners will now use the method in clinical trials.
Impact Besides the clinical trials that are now in the planning stage, our collaboration won the University of Cambridge nomination for the prestigious Rosetree Award.
Start Year 2015