Manufacture of silicon microneedles for drug & vaccine delivery

Lead Research Organisation: Swansea University
Department Name: School of Engineering

Abstract

This project will develop high-volume, quality controlled, low-cost, bespoke, silicon microneedle (MN) devices for specialised Point of Care (POC) health applications. Device specifications will be defined by a comprehensive characterisation and analysis of human skin parameters (elasticity, deformation, epidermal thickness at different sites and between different people of different ages), with respect to MN delivery A range of novel MN products will be tested in clinical skin models to demonstrate their utility for easy-application and painless transdermal injection in drug and vaccine delivery.
The key benefit of silicon MNs is the flexibility, scalability of manufacturing; it is this aspect that we focus on in this application, developing personalised but scalable manufacture for personalised medicine.
The project combines microfabrication and manufacturing expertise (SU / SPTS) with pre-clinical and clinical results from Cardiff University (CU). We will develop novel hollow MN array drug and vaccine delivery systems and demonstrate their potential in clinical practice. Considerably finer and shorter than any hypodermic syringe needle, MN devices are relatively painless, (they do not puncture deep enough into the skin to stimulate pain), and cause appreciably less damage to skin than traditional hypodermics. This is critical in where patients will require regular therapy.
MNs will provide targeted therapy to the appropriate skin compartment. E.g. in vaccination, administering antigens to the epidermis (the top 75-150 um of skin) where the immune processing Langerhans cells reside will provide a robust,whole body immune response to the vaccine. Targeting of this zone may lead to a more efficient immune response (potentially without the need for potentially harmful adjuvants) and hence dose-sparing of the difficult to manufacture vaccine.
A completely novel plasma etch and masking process will be used (SU / SPTS) to fabricate a range of sharp, hollow MNs up to 1mm in length. Currently, sharp MNs are produced using a wet chemical etch or a combined wet and plasma etch process. Our new flexible, cost-effective plasma etch process will be used to manufacture a range of MNs of different heights for personalised drug and vaccine delivery, based on the results of skin parameter testing.
Our novel bevelled MN design - developed using SPTS' deep silicon etch technology - will facilitate MN skin penetration using low injection forces. The new, simple MN drug / vaccine delivery system could revolutionise the multi billion dollar drug delivery markets enabling for the first time the effective transcutaneous delivery of a wide range of low molecular weight drug molecules including: diclofenac, ketoprofen, methotrexate, sumatriptan, methyl nicotinate and lidocaine, and targeted vaccine delivery against influenza, hepatitis C, measles, polio, rabies and tuberculosis. Optimisation of hollow MN designs will allow injection of viable drug and vaccine dosages.
Manufacture of hollow silicon MNs also opens up a whole new field of novel applications in fluid sampling combined with sensor diagnostics. Extracting interstitial fluid in volumes substantial enough for analysis will facilitate "pain free" testing of small analyte molecules. Preliminary studies will evaluate the novel MN products arising from this project for potential use in glucose testing .
Scale-up of device fabrication from small samples to full wafers, to multi-wafer production, will be achieved through integral partner SPTS' wafer-cassette loaded, multi-process-chamber tools. SPTS, the global leader in semiconductor and MEMS process equipment, is the ideal partner for high-volume, low-cost manufacture of specialised silicon MN products. SPTS will ensure manufacturing methods and materials used to make the MN devices are cost effective for scale-up production.
The MN market is ripe for exploitation using new MN designs, capable of being manufactured on a volume scale.

Planned Impact

Academic impact has been outlined in the "Beneficiaries" section. It must be stressed that SU's involvement in the EPSRC partnership will elevate them from micro/nanofabrication specialists to an internationally leading group in the MNs and microfluidics sector. Knowledge transfer between the partners will produce scientific advancements in MN design and provide new engineering solutions to medical problems.
Patient benefits:
MN delivery could revolutionise the prevention and treatment of acute and chronic diseases by facilitating simple, painless, cheap and scar free drug and vaccine delivery into the skin. Cost efficiency will be key as the microneedle platform will need to be exploited for a wide range of patients in a variety of territories. Less invasive, and more user-friendly MN injection (compared to conventional hypodermic injections) for immunisation and drug delivery applications would significantly enhance patients' quality of life through more effective and convenient treatment. The reduction in injection pain will encourage greater compliance in chronic diseases such as diabetes and improved adherence with childhood immunisation schedules. MN devices will be easy to use and could possibly be administered by the patient themselves - saving the NHS valuable time and manpower.
Industry impact and Intellectual Property (IP):
The main economic impacts to the industrial partners will be in sales of etch / deposition equipment related to production scale fabrication of the MN devices for SPTS and MN product sales from a future spin-out company from Swansea and Cardiff.
A conservative scenario, where MN kits are used for 5% of the forecast $400mn market would equate to 1 million MN chips - requiring 5 SPTS modules, generating $3m revenue per annum and extra jobs at SPTS. Revenue is expected to grow significantly over a 5 year period.
SPTS will be first to exploit traditional semiconductor and MEMS manufacturing processes for healthcare, stealing a march on their competitors in the $2bn BioMEMS market.
SPTS have calculated the cost per MN die as $0.9. At this cost, the MNs become viable for a host of other drug / vaccine delivery and fluid extraction applications.
Process flows for MN fabrication developed by SPTS and SU, could be licensed by customers, and used in Dry Etch/CVD foundries world-wide. This is SPTS' main interest as it allows the etch technology to be used in many diverse MN markets.
Initial prior art searches have revealed freedom to operate in MN design and in specific application areas and there is potential for prolific IP generation for all partners. Specific IP generated for the MN fabrication steps would belong to SPTS and SU. SU & CU would benefit from IP licensing agreements, spin-off technologies and high impact journal publications. Publication will be encouraged where not damaging to commercial interests.
Cardiff, have extensive MN expertise and will build a strong IP portfolio and further credibility in the rapidly emerging growing $400mn drug MN delivery market (Catapult).
Following clinical testing the EPSRC partners will link with foundries to manufacturer the MN devices for pharmaceutical companies.
Manufacturing and supply will be licensed with established supply chain companies leading to further job creation and MN products.
SU's Department of Research and Innovation and Cardiff's Research and Commercial Division will assist in IP protection, securing funding for clinical trials and negotiating licensing deals with Dr. Guy's and Prof. Birchall's established network of commercialisation partners including: Ig Innovations, 3M Healthcare, KPMG, Renishaw, P&S Nano, and Picofluidics - who'd all be interested in exploiting aspects of the MN technology.
 
Description Manufactured the Silicon microneedle arrays
Exploitation Route Silicon microneedles can be used for drug delivery and vaccine delivery. It can be very well adopted for various drug/vaccine delivery systems.
Sectors Education,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology

 
Description The manufactured silicon microneedles is of great potential in healthcare industries for drug delivery. This project has created strong links with our industry partner SPTS technologies. The industrial partners ahve utilised the semiconductor process developed via this grant to optimise their tools. Also this has lead to a recent success of a Welsh Government funded SMART expertise project.
Sector Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology
Impact Types Societal,Economic

 
Description ASSET
Amount £1,200,000 (GBP)
Organisation Government of Wales 
Sector Public
Country United Kingdom
Start 11/2019 
End 07/2022
 
Description EPRC Impact Acceleration award - 3
Amount £5,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 10/2017 
End 10/2018
 
Description EPSRC - Platform Grant
Amount £1,200,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 01/2016 
End 12/2020
 
Description Government of Wales - Ser Cymru III - Tackling COVID-19
Amount £99,539 (GBP)
Organisation Government of Wales 
Sector Public
Country United Kingdom
Start 10/2020 
End 03/2021
 
Description Government of Wales - Ser Cymru III Tackling COVID-19
Amount £142,237 (GBP)
Organisation Government of Wales 
Sector Public
Country United Kingdom
Start 10/2020 
End 03/2021
 
Description Internal GCRF award
Amount £9,000 (GBP)
Organisation Swansea University 
Sector Academic/University
Country United Kingdom
Start 01/2017 
End 03/2017
 
Description KESS Studentship - Sponsored by BioMEMS
Amount £52,450 (GBP)
Organisation Swansea University 
Sector Academic/University
Country United Kingdom
Start 04/2017 
End 03/2020
 
Description KESS studentship sponsored by SemiTechnologies
Amount £53,000 (GBP)
Organisation Swansea University 
Sector Academic/University
Country United Kingdom
Start 10/2017 
End 09/2020
 
Description KTP (Innoture)
Amount £120,000 (GBP)
Organisation KT partnership 
Sector Private
Country United Kingdom
Start 05/2016 
End 04/2018
 
Description KTP - SPTS
Amount £230,000 (GBP)
Funding ID 11971 
Organisation KT partnership 
Sector Private
Country United Kingdom
Start 12/2019 
End 11/2022
 
Description KTP with Innoture
Amount £134,000 (GBP)
Organisation Knowledge Transfer Partnerships 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2016 
End 07/2018
 
Description NRN Bangor
Amount £19,500 (GBP)
Funding ID NRN113 
Organisation NRN 
Sector Charity/Non Profit
Country Nepal
Start 01/2015 
End 12/2018
 
Description Collaboration with SPTS Technologies 
Organisation SPTS Technologies
Country United Kingdom 
Sector Private 
PI Contribution Development of microneedles
Collaborator Contribution Development of microneedles
Impact TSB project - multidisciplinary (life science & engineering).
 
Description GSK- microneedle collaborations 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution GSK- microneedle collaborations - information exchange on microneedle based drug delivery
Collaborator Contribution GSK- microneedle collaborations - information exchange on microneedle based drug delivery
Impact The collaboration is based on information exchange of microneedle technological knowledge and furtehr discussions are ongoing to apply to a funding bid.
Start Year 2016
 
Description Industry collaborations with IQE 
Organisation IQE Europe Limited
Country United Kingdom 
Sector Private 
PI Contribution Collaborations on semiconductor fabrication technologies
Collaborator Contribution Semiconductor wafer supply and optimisation
Impact Silicon microneedles were fabricated
Start Year 2016
 
Description Industry collaborations with Newport Wafer Fab Ltd 
Organisation Newport Wafer Fab Ltd
Country United Kingdom 
Sector Private 
PI Contribution Developing semiconductor technology processes
Collaborator Contribution wafer supply
Impact Silicon microneedles
Start Year 2016
 
Description Microneedle Collaboration with Cardiff University- 
Organisation Cardiff University
Department Department of Pharmacy
Country United Kingdom 
Sector Academic/University 
PI Contribution Manufactured Silicon microneedles
Collaborator Contribution Investigating drug delivery using silicon microneedles
Impact Device fabrication, Multi-disciplinary project (engineering, pharmacy, biology)
Start Year 2014
 
Description Microneedle Collaboration with Extraject Ltd 
Organisation Extrajet Ltd
Country United Kingdom 
Sector Private 
PI Contribution Micrineedle device
Collaborator Contribution Device fabrication
Impact Microneedle fabrication
Start Year 2013
 
Description Microneedle drug delivery - Department of CHemistry Swansea University 
Organisation Swansea University
Department Chemistry Department
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaborative project involving microneedles. We supply the microneedles and technology
Collaborator Contribution Explore the drug delivery options using microneedle arrays
Impact It is a multi-disciplinary resaerch collaboration involving chemistry, engineering and biological sciences. We are exploring the controlled drug delivery mechanism using the mcironeedle arrays
Start Year 2016
 
Description Microneedles collaboration with Imperial College London 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution To develop drug delivery strategies using microneedles
Collaborator Contribution Supply of microneedle arrays for collaborative research
Impact This is a multi-disciplinary collaborative work on the microneedle assisted controlled drug delivery
Start Year 2016
 
Description SPTS Collaboration 
Organisation SPTS Technologies
Country United Kingdom 
Sector Private 
PI Contribution Swansea University jointly developed semiconductor processes with SPTS Technologies. This has resulted in a new funding success under KTP, Innovate UK.
Collaborator Contribution Equipment supply, joint collaboration work in process development, studnetships
Impact KTP associate has been hired at Swansea University/SPTS technologies 1 KESS funded PhD studentship within College of Engineering, Swansea University Funding success with SMART expertise bid (ASSET), WG
 
Title Microneedles 
Description Microneedle technology was developed and the process for the fabrication of bespoke microneedles were developed 
IP Reference GB1709668.6 
Protection Patent granted
Year Protection Granted 2017
Licensed Yes
Impact This discovery attracted funding from EPSRC and Innovate UK through collaborations with Swansea University and SPTS technologies. Also resulted in joint-publications, studentships etc.
 
Title Microneedles Technology 
Description Silicon microneedle process technology was developed 
IP Reference WO2015059437 
Protection Patent granted
Year Protection Granted 2013
Licensed Yes
Impact Joint research projects from EPSRC and Innovate UK. Publications and joint research students
 
Title Microneedles Technology - US patent 
Description Micorneedle technology was developed for healthacre applications 
IP Reference US9919916 
Protection Patent granted
Year Protection Granted 2015
Licensed Yes
Impact Joint research projects funded by EPSRC and Innovate UK. Research publications.
 
Company Name BioMEMs Technologies Ltd 
Description Biomems Technologies Limited is a Private Limited Company. Company number assigned by Companies House is 09360659. 
Year Established 2014 
Impact Develops microneedle technologies for Bio-MEMs Applications
Website http://companiesuk.co/none-supplied/biomems-technologies-limited
 
Company Name Extraject Technologies Ltd 
Description Extraject Technologies Ltd was incorporated on 21 Jan 2013 and is located in Cardiff. The company's status is listed as "Active" and it currently has 3 directors. The company's first director was Dr Dominic John Finbar Griffiths. Extraject Technologies Ltd does not have any subsidiaries. 
Year Established 2013 
Impact Other research and experimental development on natural sciences and engineering
Website https://companycheck.co.uk/company/08369024/EXTRAJECT-TECHNOLOGIES-LTD/summary
 
Company Name Semitechnologies Limited 
Description SEMITECHNOLOGIES LIMITED is a Private Limited Company from SWANSEA. The major activity is to develop semiconductor technologies for the solar energy industry. 
Year Established 2013 
Impact Developing semiconductor technologies for the solar energy industry.
Website http://www.checkcompany.co.uk/company/08658150/SEMITECHNOLOGIES-LIMITED
 
Company Name SmartNanotech Ltd 
Description The firm was registered as a PLC on Tue, 20th Aug 2013. The firm has been actively competing on the British market for 3 years. This business is gotten hold of Ty Derw Lime Tree Court Cardiff Gate Business Park in Cardiff. The postal code assigned is CF23 8AB. This business declared SIC number is 71122 and their NACE code stands for Engineering related scientific and technical consulting activities. Smart Nanotech Ltd filed its latest accounts up to 2015-08-31. The latest annual return was filed on 2015-08-20. For as long as three years Smart Nanotech Ltd has been the local leader in the field. For 3 years, this specific company has only been supervised by an individual managing director: Dr Jie Gao who has been leading it since Tue, 20th Aug 2013. 
Year Established 2013 
Impact The company involves in engineering related scientific and technical consulting activities
Website http://www.bizdb.co.uk/company/smart-nanotech-limited-08658334/
 
Description Advanced Biomaterials and Biosensor workshop (13-15 November 2018, India) - Zari 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact 17 applications from the UK were selected to attend the workshop.
Advanced Biomaterials and Biosensor workshop (13-15 November 2018, India)
Graphene-based Biosensor
Year(s) Of Engagement Activity 2018
 
Description Microneedle Conference 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Posted Presentation by Dr. Yufei Liu
Year(s) Of Engagement Activity 2014
 
Description Science & the Assembly 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Prof. Guy attended the Science & the Assembly event in Cardiff
Year(s) Of Engagement Activity 2019
 
Description "Graphene 2018" conference, Dresden, Germany, 26-29 June 2018 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact "Graphene 2018" conference, Dresden, Germany, 26-29 June 2018
E. D. Ahmadi, J. Mitchell, R. Bigham, M. Ali, G. Looker, Z. Tehrani, A. Devadoss, P. Braeuninger, C.M. Fung and O.J. Guy
Study the Effect of Mono- and Bi-layer Photoresists in Graphene Biosensor Fabrication
Year(s) Of Engagement Activity 2018
 
Description 28th Anniversary World Congress on Biosensors (Miami, Florida, USA - 12-15 June 2018) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Fully characterisation of Si3N4 and Al2O3 passivation layer in fabrication of graphene-based biosensor
E.D. Ahmadi, J. Mitchell, R. Bigham, Z. Tehrani, A. Devadoss, P. Braeuninger, C.M. Fung, O.J. Guy
28th Anniversary World Congress on Biosensors (Miami, Florida, USA - 12-15 June 2018)
Year(s) Of Engagement Activity 2018
 
Description 2nd International Conference on Materials Science and Materials Chemistry- Keynote 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Prof. Owen Guy delivered an invited Keynote lecture at 2nd International Conference on Materials Science and Materials Chemistry in London
Year(s) Of Engagement Activity 2019
URL https://biomat.net/site2/events/2nd-international-conference-on-materials-science-and-materials-chem...
 
Description 31st Nano Congress for Future Advancements 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact 31st Nano for Future Advancements held during August 29-31,2019 at London, UK (Heathrow Park Inn)

Prof. guy delivered Plenary lecture
Year(s) Of Engagement Activity 2019
 
Description Advanced Biomaterials and Biosensor workshop - Ehsahneh 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact 17 applications from the UK were selected to attend the workshop.
Advanced Biomaterials and Biosensor workshop (13-15 November 2018, India)
Fully Characterisation of Graphene-based Biosensor Fabricated by Mono- and Bi-layer Photoresist
Year(s) Of Engagement Activity 2018
 
Description Biosense Dementia Plymouth - Poster by Jacob Mitchel 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Biosense Dementia 2017 workshop was arranged by Plymouth university in June 2017. Jacob Mitchel, PhD student from prof. Owen's group has attended the devent and presented a poster.
Year(s) Of Engagement Activity 2017
URL https://www.plymouth.ac.uk/whats-on/biosense-dementia
 
Description Biosense Dementia Plymouth - Poster by Ryan Bigham - Best poster 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Biosense Dementia 2017 workshop was arranged by Plymouth university in June 2017. Ryan Bigham, PhD student from prof. Owen's group has attended the devent and presented a poster entitled "Graphene based biosensor for detection of dementia biomakers" and won the best poster prize!
Year(s) Of Engagement Activity 2017
URL https://www.plymouth.ac.uk/whats-on/biosense-dementia
 
Description CoInnovate - Cardiff Oct 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Prof. Owen Guy participated in CoInnovate - Cardiff Oct 2016
Year(s) Of Engagement Activity 2016
URL https://businesswales.gov.wales/constructionfutureswales/events/coinnovate-2016-11th-12th-october-20...
 
Description Compound Semiconductor Meeting - Cardiff Sept 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Prof. Owen guy attended Compound Semiconductor Meeting - Cardiff Sept 2016
Year(s) Of Engagement Activity 2016
 
Description Early Career Researchers Meeting (ECRM) conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Early Career Researchers Meeting (ECRM) conference, held by the British Society of Nanomedicine, which took place from 6th-7th August 2018
Year(s) Of Engagement Activity 2018
 
Description Electrochem 2017 - Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Dr. Anitha Devadoss attended the Electrochem 2017 event between September 10-12 at Birmingham university. Interaction with the leading researchers in the field of Electrochemistry.
Year(s) Of Engagement Activity 2017
URL http://www.rsc.org/events/detail/26104/electrochem-2017
 
Description Engineering VIP Alumni Event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other audiences
Results and Impact Prof. Owen guy participated in the Engineering VIP Alumni Event
Year(s) Of Engagement Activity 2016
 
Description Graphene 2018 Dresden Conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Graphene 2018 Dresden Conference. "Passivation procedures for Graphene Biosensors".
Year(s) Of Engagement Activity 2018
 
Description Innovate UK - New project workshop - Swindon 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Prof. Owen Guy attended the Innovate UK - New project workshop at Swindon, UK.
Year(s) Of Engagement Activity 2016
 
Description International Women in Engineering Day 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact International women in Engineering 2017 event is organised within Swansea University to showcase the Successful women in Engineering discipline. Dr. Anitha Devadoss, presented her international work experinece to the graduate/postgraduate/early career researchers.
Year(s) Of Engagement Activity 2017
 
Description Invited Talk at ANEH 2018 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact International COnference of Advanced Nanomaterials for Energy Environment and Healthcare 2018. Dr. Anitha Devadoss delivered an invited Talk.
Year(s) Of Engagement Activity 2018
 
Description Invited Talk at Biosensors Workshop 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Invited Talk at Biosensors Workshop- Life Sciences Hub Wales, Bangor University, 4-5th of September 2017
Year(s) Of Engagement Activity 2017
 
Description Invited talk and committee member for Biosensors and Bioelectronics Symposium 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Dr. Zari tehranidelivered an invited talk and committee member for Biosensors and Bioelectronics Symposium - Sweden, 3rd -6th of June 2018
Year(s) Of Engagement Activity 2018
 
Description Invited talk at 7th Innovation Academy Symposium 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Delivered an invited talk in London at 7th Innovation Academy Symposium.
Year(s) Of Engagement Activity 2017
 
Description Invited talk at CoInnovate  
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Delivered an invited talk at the coinnovate event organised by Ser Cymru NRN at Cardiff on 24/01/2018
Year(s) Of Engagement Activity 2018
 
Description Invited talk at CoInnovate, Cardiff 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Delivered an invited talk on advances in engineering technologies for healthcare applications
Year(s) Of Engagement Activity 2017
 
Description Invited talk at Pfizer visit to Swansea University 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Senior managemnet team from Pfizer visited Swansea University. we have represented the Medical Devices research team within Swansea university and future collaborations were discussed.
Year(s) Of Engagement Activity 2017
 
Description Invited talk at the 2nd Annual Infectious Diseases Diagnostics Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Prof. Guy delivered Invited talk at the 2nd Annual Infectious Diseases Diagnostics Conference
Year(s) Of Engagement Activity 2019
 
Description Invited talk at the Conference Infectious Disease Diagnostic 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Invited presentation at the Conference Infectious Disease Diagnostic, 21st - 22nd February, 2018, London, UK
Year(s) Of Engagement Activity 2017
 
Description MSCA Fellowships writing Summer School - South Wales Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other audiences
Results and Impact The post doctoral Researcher, Dr. Anitha Devadoss attended this MSCA Fellowships writing Summer School - South Wales Workshop between 4-5 July, 2016 hosted by cardiff University.
Year(s) Of Engagement Activity 2016
URL http://www.nrn-lcee.ac.uk/documents/SummerSchoolFlyer.pdf
 
Description Manchester Graphene KTN event Nov 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Prof. Owen guy participated in the event : Showcase your innovation at Innovate 2016, 2-3 Nov 2016, Manchester
Year(s) Of Engagement Activity 2016
URL https://connect.innovateuk.org/web/chemistryinnovationktn/article-view/-/blogs/showcase-your-innovat...
 
Description Meeting with Derek Vaughan MEP 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Prof. Owen Guy attended an event - Meeting with Derek Vaughan MEP
Year(s) Of Engagement Activity 2016
 
Description Micro needle lecture by Dr. Pey Fen Eng 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Undergraduate students
Results and Impact Delivered lecture on Microneedle fabricationa dn its applications
Year(s) Of Engagement Activity 2014,2015
 
Description MicroTAS 2016 in Dublin 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Undergraduate students
Results and Impact Student Jacob Mitchell presented a poster at MicroTAS 2016 in Dublin
Year(s) Of Engagement Activity 2016
URL http://www.microtas2016.org/
 
Description Microfluidic Congress Nov 2015 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Poster Presentation by Dr.Pey Fen Eng
Year(s) Of Engagement Activity 2015
URL http://www.globalengage.co.uk/microfluidics/posters.html
 
Description NEN Meeting - Dec 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Prof. Guy attended NEN Meeting in December 2016
Year(s) Of Engagement Activity 2016
URL http://northendbreezes.com/the-north-end-neighbours-nen-december/
 
Description NPL Graphene & 2D Materials Conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Fully Characterisation of Graphene-based Biosensor Fabricated by Mono- and Bi-layer Photoresist
E. D. Ahmadi, J. Mitchell, M. Ali and O.J. Guy
NPL Graphene & 2D Materials Conference (NPL, Teddington, London, UK - 9-10 October 2018)
First poster winner prize
Year(s) Of Engagement Activity 2018
 
Description SEMI Europe visit 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact SEMI Europe visit - Prof. Guy delivered Invited talk
Year(s) Of Engagement Activity 2019
 
Description Speakers for Soap Box Science Swansea 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Dr. Zari tehrani was a Speakers for Soap Box Science Swansea, Pedestrian area Oxford Street, 23rd of June 2018
Year(s) Of Engagement Activity 2018
 
Description Swansea Science Festical - 2019 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Dr. Anitha Devadoss, orgaised a stall on healthcare technologies and interacted with school children and the general public.
Year(s) Of Engagement Activity 2019
 
Description Swansea Science Festival 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Swansea Science Festival 2017 event was held at National waterfront Museum between September 9-11 2017. A stall was displayed at the event demonstrating the biosensors research activity within Swansea University. Our entire group was involved in this and the event was a grand success . General public, children and graduate students attended the event.
Year(s) Of Engagement Activity 2017
URL http://www.swansea.ac.uk/science/news/swanseasciencefestival2017.php
 
Description UK Digital Economy Crucible 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Post doctoral researcher Dr. Adam Williams attended UK Digital Economy Crucible 2016
Year(s) Of Engagement Activity 2016
URL http://cherish-de.uk/crucible/alumni/
 
Description WCCB-2019, Barcellona, Invited Talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Prof. Owen Guy delivered Invited Talk at WCCB-2019, Barcelona, Spain, on May 22-24, 2019
Year(s) Of Engagement Activity 2019
URL https://10times.com/wccb-castelldefels
 
Description secondary school student outreach programme 2015 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Prof Owen Guy and Prof James Birchall has research presentation and demonstrate in a secondary school student outreach programme 2015
Year(s) Of Engagement Activity 2015