RDM Healthcare Research Network

Lead Research Organisation: University of the West of England
Department Name: Faculty of Business and Law

Abstract

'Re-distributed manufacture' (RDM) is defined as: Technology, systems and strategies that change the economics and organisation of manufacturing, particularly with regard to location and scale. The potential for smaller-scale local manufacturing (RDM) and its contribution to UK GDP was made clear at the EPSRC Re-Distributed Manufacturing Workshop in November 2013. As the Workshop report concluded, successful implementation in UK industry presents many challenges and opportunities. The creation of a series of Networks to explore and define these issues, and the research agenda required to resolve them, is a timely approach to harnessing the expertise of a multidisciplinary community into a future coherent research initiative.

Our focus on manufacture of healthcare devices and therapies reflects the socio-economic importance of healthcare within the UK. The NHS has a turnover of some £121bn in the UK and serves a population of around 64m citizens - marginal advances in technology and services can have large impacts. Healthcare technologies are an EPSRC Challenge theme. The proposed RDM in Healthcare Network's (RiHN) objectives will support all four of the strategic priorities identified by EPSRC (novel treatment and therapeutic technologies; enhanced prediction and diagnosis in real time at the point-of-care; technologies for a healthy life course; and design, manufacture and integration of healthcare technologies).

RDM may change the delivery of healthcare products, enhancing national competitiveness and citizen well-being through: a) Cost reduction through terminal customisation or delayed manufacture based upon flexible intermediate products; b) Just-in-time delivery, particularly of perishable healthcare goods, c) Reduction of operational overheads by sharing support services between local manufacturing hubs, d) Management of capacity by distributing production through scale-out, rather than scale-up, e) Avoidance of placing high up-front capital cost at riskby building small production units in response to increase in demand instead of single large factories.

There are key challenges to realising these benefits: Technical needs must meet the appropriate regulatory standard; new training patterns must be established to maintain operating quality from a distance; social and inter-personal features must be addressed to enhance quality of life, incorporating quality assurance into the business structures; new customer-supplier relationships must be forged.

RiHN aims to explore these challenges and incentives and will be led by a multi-disciplinary team drawn from manufacturing, management, human factors and healthcare technologies, combining the expertise required from both the social sciences and engineering. The consortium has experience in delivery of major national networks and research centres and will build on the established relationships that the team have with industry, clinical networks, the NHS, regulatory bodies, policy-makers, academics and end users.

RiHN aims to develop the research agenda for RDM in healthcare, engaging with relevant academic and user communities through workshops and user engagement events, and through conducting feasibility studies in five distinct areas: 1. Medical Devices; 2. Pharmaceuticals; 3. Advanced Therapeutics (cell and tissue); 4. Dentistry; 5. Diagnostics. In doing so, RiHN intends to establish a community of practice for RDM in Healthcare, outlining the future direction for research, which will be published in a white paper. The outputs of RiHN will also be disseminated through a website, presentations at relevant national and international conferences, participation at other RDM Network events and research centres and a Special Issue journal (Journal of Operations Management) presenting the findings of the feasibility studies. A final report will be produced, sent electronically to all interested parties, and made available on RiHN's website.

Planned Impact

This Network will work directly with beneficiaries to ensure that feasibility studies funded by the network are of relevance to a range of stakeholders, and have the potential for implementation in a healthcare context. User engagement events and workshops with interested and relevant parties will ensure that stakeholders have the opportunity express their views and shape the research agenda. Cross-sectoral learning will be supported through collaboration with the other RDM Networks.

A range of commercial private sector beneficiaries will include small and medium sized enterprises who participate in network meetings, develop or sell technologies and products (such as 3D scanners, mobile app developers, specialist manufacturers of customised parts, pharmacists) that will be used to realise RDM activities. In addition to these smaller businesses, large organisations (such as Smith & Nephew, Surgical Innovations Group Plc) will engage with the network as participants in projects, providing expertise and scoping of feasibility topics. The benefit of participation and engagement with this project for the commercial sector will include increased knowledge and understanding of the potential for new technologies and networks of technologies in the healthcare sector, understanding of personal and societal attitudes towards RDM in healthcare applications, and links with potential commercial partners in future RDM healthcare activities.

The healthcare sector, in particular the NHS, will benefit from this project, through the increased awareness of the appropriate mechanism through which new models of distributed manufacturing can be implemented within a range of different healthcare products, from pharmaceuticals, to cell based therapeutics and personal medical devices. This awareness will inform cost effectiveness analysis of new healthcare approaches, and ensure that the regulatory and legal considerations of altering models of healthcare manufacturing are appreciated throughout the supply and user chain. In the future, based upon insights from this Network, medical personnel including doctors, pharmacists, nursing staff and carers, will also benefit, due to higher quality products being delivered, leading to easier introduction of healthcare products and devices to patients, increased personalisation of devices (resulting in fewer side effects due to customised devices with improved 'fit'.

The general public will benefit through more personalised models of healthcare manufacture and delivery, improved health outcome resulting from higher levels of customisation and speed of production, and increased satisfaction with their healthcare provision due to the reduced need to travel to specialist providers, coupled with the retention of communication with and support from relevant healthcare experts.

Publications

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Harrison R (2016) Automating decentralized manufacturing of cell & gene therapy products in Cell and Gene Therapy Insights

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Lim S (2018) Consumer-driven e-commerce A literature review, design framework, and research agenda on last-mile logistics models in International Journal of Physical Distribution & Logistics Management

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Montalbano G (2018) Synthesis of bioinspired collagen/alginate/fibrin based hydrogels for soft tissue engineering. in Materials science & engineering. C, Materials for biological applications

 
Title 3-D Bioprinting of Islet Micro-tissues to Redistribute Manufacture for Treatment of Type 1 Diabetes 
Description Feasibility study video 
Type Of Art Film/Video/Animation 
Year Produced 2016 
Impact Provided an outline of the RiHN programme's funded project investigating the potential of 3D bioprinting 
URL http://rihn.org.uk/member-videos/
 
Title 3D Bioprinting: Commercialising Personalised ATMP/Device Combination Products 
Description Feasibility study video 
Type Of Art Film/Video/Animation 
Year Produced 2016 
Impact Provided an outline of the RiHN programme's funded project investigating the potential of 3D bioprinting 
URL http://rihn.org.uk/member-videos/
 
Title Cell Microfactories: Feasibility Study in the Redistributed Manufacture of Cell-Based Therapeutics 
Description Feasibility study video 
Type Of Art Film/Video/Animation 
Year Produced 2016 
Impact Provided an outline of the RiHN programme's funded project investigating the potential of cell microfactories 
URL http://rihn.org.uk/member-videos/
 
Title Redistributed Manufacturing for home-use medical devices 
Description Feasibility study video 
Type Of Art Film/Video/Animation 
Year Produced 2016 
Impact Provided an outline of the RiHN programme's funded project investigating the potential of 3D printing of medical devices in the home 
URL http://rihn.org.uk/member-videos/
 
Title Redistributed Manufacturing in Healthcare Network 
Description Outline of research programme purpose and explanation of the potential value of redistributed manufacturing in healthcare. Also invites participation in the programme and promotes the website 
Type Of Art Film/Video/Animation 
Year Produced 2016 
Impact To those who are not familiar with RDM or the scope of the term, this video delivered a simple message to interested parties 
URL http://rihn.org.uk/member-videos/
 
Title Redistributed Manufacturing in Pharma 
Description Feasibility study video 
Type Of Art Film/Video/Animation 
Year Produced 2016 
Impact Provided an outline of the RiHN programme's funded project investigating the potential of RDM in pharma 
URL http://rihn.org.uk/member-videos/
 
Description RiHN brought together a multi-disciplinary team of academics and practitioners and delivered a variety of workshops covering new areas of investigation, technology roadmapping, supply reconfiguration and regulation. RiHN funded five feasibility studies covering potential applications of RDM in areas involving cell microfactories and various forms of 3D printing (advanced therapies, diagnostic medical devices and single dosage pharmaceuticals). The programme benefited from close engagement with the healthcare industry with specialists from manufacturing and engineering, management, law, consulting, medical devices, regenerative medicine, health services, and pharmaceuticals, culminating in the production of the RiHN White Paper "Redistributed manufacturing in Healthcare: Creating New Value through Disruptive Innovation".
The RiHN White Paper serves as a foundation for discussing future technological roadmaps and engaging the wider community and stakeholders, as well as policy makers, in assessing the potential impact of RDM. The RiHN findings, as presented in the White paper, are of particular value for policy implementers and funders seeking to specify action and to direct attention where it is needed. The RiHN findings are also useful for the research community, to support their proposals with credible research propositions and to show where collaborations with industry and the public sector will deliver the most benefit.
A comprehensive review of the research material generated by RiHN identified four future capability needs and challenges that must be overcome if the potential of RDM applications is to be realised:
Challenge theme 1: Developing the enabling advanced production platform systems and supporting infrastructure for RDM
Challenge theme 2: Development of advanced analytics and characterisation technology to drive automation of enabling production platforms
Challenge theme 3: Evolution and synthesis of adaptive regulatory review, governance and approval pathways
Challenge theme 4: Developing innovative frameworks for business model and organisational transformation
The RiHN-funded feasibility studies provided evidence of priorities amongst emerging needs, opportunities and challenges involved in taking forward future healthcare research in RDM. The viability of RDM and its successful deployment ultimately depends on the identification of credible platform designs and sound RDM business models. The proposed RiHN R&D agenda presents recommendations across industry, regulatory affairs and business operations. The priority areas for future R&D can be summarised as follows:
A. The development of automated production platform technologies and supporting manufacturing infrastuctures, focusing on:
• The development and performance of manufacturing technologies (including hardware, mechanisation, software, and programmable components)
• Developing industry consensus on need and expectations for the development of technical standards for manufacturing technologies and critical components
• Building an innovation-centred, systems-based model for human capital development to support advanced manufacturing technology innovation
B. Development of advanced analytics and characterisation metrology to:
• Advance the development of quantitative, real-time analytical technologies and corresponding data analysis tools
• Progress the discovery and identification of quantifiable measures of product quality
• Advance data analytics, machine interconnectivity and real-time acquisition, management and security of multiple sources of data
C. Setting the framework for regulatory and governance Pathways, which will involve:
• Assessing the potential impact of automated production platform technologies on product market approval pathways
• Evaluating the impact of emerging healthcare sector specific RDM strategies on extant legal and regulatory governance frameworks
• Extending the UK's ability to provide the relevant specialised regulatory science skills for emerging manufacturing technologies and advanced therapies
D. Frameworks for Business Model and Organisational transformation, including:
• Compiling the clinical and economic evidence base
• Raising the level of organisational capability readiness
• Formulating alternative financial reimbursement models
Exploitation Route RiHN has identified that the current value of redistributed manufacturing lies in niche applications such as emergency and military medicine and humanitarian aid. Consequently, RiHN research outcomes have the potential to be taken forward in such scenarios. Consequently, RiHN is currently working with Defence Medical Services to explore how RDM could enhance medical responses in deployed operations and emergency scenarios, identifying potential approaches that will support the tailoring of conventional medical systems to bespoke defence challenges. RiHN has already received initial EPSRC workshop funding, but intends to take this further through undertaking a larger scale research project with the defence sector and other frontline services e.g. paramedics

Additional funding for key niche therapies investigated by RiHN, such as cellular therapies could help further the systematic understanding of how healthcare delivery functions within these niches and enable implementation of key innovations towards not only improving patient outcomes, but also saving the NHS money through process redistribution.
Through RiHN funding, one of the feasibility studies now has a viable product, the PeePod, that could follow the RDM model. The research team involved in the PeePod study intend to set up a prototype manufacturing pipeline and assess the practical difficulties in implementing such a model.

Overall, RiHN has identified a need to undertake future studies to assess commercial feasibility of RDM technologies in the near future (<10 years), once the technological capabilities are more clearly established, it is important that hospitals, universities and businesses collaborate to ensure the interests of all parties combine to realise future developments and build a business case for the adoption of RDM in the healthcare sector.

The social and environmental benefits of the RDM model have been outlined by RiHN and other EPSRC RDM networks, future studies could build on these findings to investigate how firms have transitioned to an RDM system to enhance their environmental and social profile. For the NHS, future research could be undertaken into measuring the sustainability impact of medical products manufactured through conventional routes versus RDM, aiding the decision to make locally e.g. within a hospital, or buy from suppliers.

Finally, RiHN will maintain its online presence and will disseminate future findings electronically and through journal articles e.g International Journal of Operations Management (IJOPM), Production, Planning and Control (PPC), and conference papers e.g. European Operations Management Association (EurOMA).
Sectors Aerospace, Defence and Marine,Agriculture, Food and Drink,Chemicals,Communities and Social Services/Policy,Construction,Creative Economy,Digital/Communication/Information Technologies (including Software),Education,Electronics,Energy,Environment,Financial Services, and Management Consultancy,Healthcare,Government, Democracy and Justice,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology,Security and Diplomacy,Transport,Other

URL http://www.rihn.org.uk
 
Description The primary goal of RiHN has been to enable a multidisciplinary, multi-perspective debate on the potential of Re-Distributed Manufacturing (RDM) in healthcare industries and organisations, and to define a research agenda that will overcome the challenges and issues that prevent its realisation. The five feasibility studies have been an important part of the definition process. The network brought together partners from different academic, industrial and health sector communities to ensure that the feasibility studies in redistributed manufacturing (RDM) for healthcare were informed directly by societal and commercial needs. Results from these studies, conducted by researchers drawn from the manufacturing, healthcare and social science academic communities, have had a direct impact on a range of users, including industry stakeholders, healthcare providers and the general public (as 'prosumers' of healthcare). Impact as a philosophy therefore underpins this networked approach, and this multidisciplinary network continues to bring together a group of investigators who have extensive experience in working with such mechanisms. There are a number of specific activities that have contributed to the impact of RiHN: • Network meetings that have brought together industry, user, health sector and academic partners • A sandpit approach to identification and selection of multidisciplinary feasibility studies • Electronic and social media communications to disseminate the outputs and activities of the network • Specific focused events targeting key populations of relevance to the network e.g. clinical networks, pharmaceutical industry and healthcare regulators RiHN has worked directly with beneficiaries to ensure that the feasibility studies funded by the network have been of relevance to a range of stakeholders, and have the potential for implementation in a healthcare context. This was undertaken by means of a rigorous selection process involving a panel of experts representing key beneficiaries drawn from industry, public healthcare organisations and policy and regulatory bodies. Key beneficiaries include: 1) The commercial private sector, including small and medium sized enterprises (that sell technologies and products used to realise RDM) and large organisations (such as Smith & Nephew, Peacocks) have engaged with the network, attending network meetings and providing expertise during the scoping of feasibility topics. The benefits for commercial organisations in participating and engaging with RiHN and the feasibility studies includes: a. increased knowledge and understanding of the potential for new technologies and networks of technologies in the healthcare sector b. understanding of personal and societal attitudes towards RDM in healthcare application c. an improved understanding of how RDM techniques can enhance supply chain resilience. Areas of particular benefit include the identification of potential points of failure in the supply chain and how RDM can reduce waste and meet unexpected peaks in demand. d. Development of links with potential commercial partners in future RDM healthcare activities. 2) The healthcare sector, in particular the NHS, have benefited from this project, through: a. increased awareness of the appropriate mechanism through which new models of RDM can be implemented within a range of different healthcare products, from pharmaceuticals, to cell based therapeutics and personal medical devices. This awareness can be used to inform cost effectiveness analysis of new healthcare approaches, ensuring that the regulatory and legal considerations of altering models of healthcare manufacturing are appreciated throughout the supply and user chain. b. Medical personnel, including doctors, pharmacists, nursing staff and carers have benefited through engagement in the feasibility studies, promoting an enhanced understanding by the user community of how RDM can support the development of higher quality products. This in turn should lead to easier introduction of healthcare products and devices to patients, and increased personalisation of devices (resulting in right-first-time therapies and fewer side effects due to device 'fit' and right-first-time therapies). 3) Healthcare regulators have benefited from the important contribution that the feasibility study and workshop findings have made in developing an understanding of likely pathways that will emerge through a move towards RDM, contributing towards the development of proportionate regulation. 4) The general public will benefit from the findings as these have fed through to industry, policy-makers and regulators, supporting a move towards more personalised models of healthcare manufacture and delivery. Feasibility study findings suggest patients have no concerns about using RDM-manufactured devices and they should benefit from improved health outcomes resulting from higher levels of customisation and speed of production, and increased satisfaction with their healthcare provision due to the reduced need to travel to specialist providers.
First Year Of Impact 2017
Sector Aerospace, Defence and Marine,Education,Electronics,Environment,Financial Services, and Management Consultancy,Healthcare,Government, Democracy and Justice,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology,Other
Impact Types Societal,Economic,Policy & public services

 
Description Additive bio-manufacturing: 3D printing for medical recovery and human enhancement
Geographic Reach Europe 
Policy Influence Type Participation in a advisory committee
URL https://epthinktank.eu/2017/11/10/what-if-we-could-3d-print-our-own-body-parts-science-and-technolog...
 
Description Navigating Regulatory requirements
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
URL http://rihn.org.uk/event/navigating-regulatory-requirements-for-redistributed-manufacturing-in-healt...
 
Description EPSRC Workshop Funding
Amount £14,622 (GBP)
Funding ID EP/P010660/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start 02/2017 
End 04/2017
 
Title RiHN Membership Database 
Description We have developed a membership database of 232 individuals who have helped us advance the agenda of redistributed manufacturing in healthcare. Around 40% of these members are from outside academia (SMEs = 31, Large Enterprises = 12, Government or Public Sector = 44, Other = 4). A range of disciplines across are represented including: Manufacturing and Engineering (21%), Management, Policy, Law, Supply Chain (21%) Innovation and Consulting (19%), Medical Devices (11%), Regenerative Medicine (9%), Health Services (9%), Pharma, Biology and Chemistry (8%) and Sponsors (2%). 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact This has allowed us to reach a specialist audience. In-time, it may be able to help inform a new KTN map of actors involved in RDM. 
 
Description Cell & Gene Therapy Catapult (Feasibility study 1) 
Organisation Cell Therapy Catapult
Country United Kingdom 
Sector Academic/University 
PI Contribution The research team working on Feasibility Study 1 were able to update the Cell & Gene Therapy catapult on redistributed manufature and how it relates to cell therapies detailing economic / technical / legal / regulatory gaps and solutions
Collaborator Contribution The Cell and Gene therapy catapult were able to provide input regarding regulatory aspects of RDM
Impact The outputs of this partnership relate to feasibility study 1 and are listed in the relevant sections. The collaboration is multi-disciplinary covering celltherappies, supply chain management, regulation and innovation mamangement
Start Year 2015
 
Description Innovate UK 
Organisation Innovate UK
Country United Kingdom 
Sector Public 
PI Contribution RiHN has informed Innovate UK of developments in UK healthcare manufacturing
Collaborator Contribution A representative from Innovate UK is a member of the RiHn Steering Group and has attended RiHN events, reviewed feasibility study proposals and has promoted RiHN events and outputs via social media and the Innovate UK website
Impact Innovate UK have been instrumental in promoting the work of RiHN to UK manufacturing organisations
Start Year 2015
 
Description KTN UK 
Organisation Knowledge Transfer Network
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution We update KTN UK on events, findings and outputs relating to RDM to keep KTN informed of development in manufacturing, particularly with respect to healthcare. RiHN also promotes relevant KTN events, outputs and postings via its website and social media accounts.
Collaborator Contribution KTN UK have provided representatives that have attended events and have a representative ion the RiHN Steering Group. KTN UK have also hosted a RiHN event at KTN UK London offices
Impact KTN UK have hosted an event at its London offices
Start Year 2015
 
Description Lime Associates 
Organisation Lime Associates
Country United Kingdom 
Sector Private 
PI Contribution We have provided Lime Associates with the opportunity to engage and be informed in mapping the future landscape of redistributed manufacturing in healthcare and the impact this may have on healthcare delivery
Collaborator Contribution The partner is a member of our Steering Group and has actively promoted the network through social media, press releases, presenting and chairing events, most notably the launch of the feasibility studies in Nov 2015
Impact Press releases and promotion of the network
Start Year 2015
 
Description Medicines Manufacturing Industry Partnership 
Organisation Medicines Manufacturing Industry Partnership
Country United Kingdom 
Sector Private 
PI Contribution The RDM in healthcare feasibility study had direct involvement of members of the Medicines Manufacturing Industry Partnership (MMIP), a pharmaceutical trade association reporting to the Association of British Pharmaceutical. Industry (ABPI) Members of the MMIP participated in interviews, focus groups and presented at the one day knowledge exchange event at the University of Sussex
Collaborator Contribution Members of the MMIP participated in interviews, focus groups and presented at the one day knowledge exchange event at the University of Sussex. Members of the MMIP also helped with introductions to case study companies including Pfizer, GSK and Astra Zeneca
Impact The head of the MMIP was the plenary speaker at the future of pharmaceutical supply chains knowledge exchange event held at the University of Sussex. The findings from this event informed the strategic priorities for the trade association and led to multi-disciplinary collaborative funding application for the ESRC Brexit priority grant (Decision still pending)
Start Year 2016
 
Description Medilink East Midlands 
Organisation East Midlands Medilink
Country United Kingdom 
Sector Private 
PI Contribution The project is informing healthcare suppliers of how redistributed manufacturing has the potential to transform the delivery of healthcare within the UK and how this may impact on supply networks.
Collaborator Contribution Medilinks EM have promoted engagement with healthcare suppliers and have provided support in convening a network event to launch the selected feasibility studies in November 2015
Impact Research Events - participants at the event held at 19th November 2015 were asked to map supply chains and then to consider how these would be transformed by redistributed manufacturing
Start Year 2015
 
Description Medilink East Midlands 
Organisation East Midlands Medilink
Country United Kingdom 
Sector Private 
PI Contribution RiHN ran a Special Interest Group on redistributed manufacturing for East Midlands Medilinks members presenting the RiHn feasibility studies and running a workshop on value chain mapping
Collaborator Contribution Medilinks have promoted the work of RiHN via its website and social media and hosted the Special Interest Group where RiHN launched the feasibility studies
Impact Supply Chain Special Interest Group
Start Year 2015
 
Description VoiceNorth 
Organisation Newcastle University
Department Voice North
Country United Kingdom 
Sector Academic/University 
PI Contribution Patients were able to develop an understanding of RDM and how it ould lead to manufacture of medical devices for home use.
Collaborator Contribution The original brief for Feasibility Study 3 (the PeePod) was for a device that would enable patients to perform an embarrassing clinical investigation with dignity, and in their own home. A large part of the brief for that project was to assess the patient's interaction with the device, for which we had overwhelmingly positive feedback. The collaboration enabled the research team on this feasibility study to conduct a major PPI and through the collaboration it was found that patients have no concerns about using RDM-manufactured devices. However, they felt that home manufacture was beyond the mean of all but the most technically adept patients
Impact Outputs relating to this feasibility study are listed in the relevant study but as a result of the collaboration the team found that the outcomes werepositive, to the extent that they would be happy to take the device into clinical practice.
Start Year 2015
 
Description WEAHSN 
Organisation West of England Academic Health Science Network
Country United Kingdom 
Sector Academic/University 
PI Contribution The findings of the research undertaken by the project will help inform WEAHSN of the potential impact that redistributed manufacturing will have on healthcare provision
Collaborator Contribution The director of the WEAHSN is on the projects Steering Group and assessed the feasibility study proposals submitted to the network
Impact WEAHSN are supporting the project in terms of enabling engagement with relevant NHS commissioning and procurement teams to capture views on current supply arrangements, particularly in high value areas and to consider the potential disruptive impact of redistributing manufacturing on healthcare delivery. WEAHSN is also supporting clinical engagement
Start Year 2015
 
Description West Sussex County Council 
Organisation West Sussex County Council
Country United Kingdom 
Sector Public 
PI Contribution Findings from the RDM in healthcare feasibility study helped inform West Sussex County Council on the formation of a Life Science Research Cluster in West Sussex.
Collaborator Contribution A member of West Sussex County Council helped advise the research project and provided introductions to pharmaceutical firms located in West Sussex to participate in interviews
Impact The findings from the feasibility study hellped inform decisions on the formation of a life sciences research cluster in West Sussex Country Council
Start Year 2016
 
Description @EPSRCRiHN twitter account 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact RiHN has set-up its own twitter account @EPSRCRiHN which has a good following from a broad array of individuals and organisations. All events have had allocated Twitter feeds enabling 'live reporting' which is also linked to the network website.The Twitter account had stimulated greater interest in RiHN and its activities as evidenced by messages sent via Twitter and tweets and retweets of issues relating to RiHN and RDM.
Year(s) Of Engagement Activity 2015,2016,2017
URL https://twitter.com/EPSRCRIHN
 
Description Bringing healthcare into our living rooms - press release 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Press release to promote interest and engagement in RiHN
Year(s) Of Engagement Activity 2016
URL http://www.publicnow.com/view/48866450C6DD8815AE1BE5E2DBBBD346C1F24851
 
Description Centre For Healthcare Technologies Launch Event, February 2016, Nottingham, UK, (Feasibility Study 5) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact On the 29th February the University of Nottingham and the Nottingham University Hospitals NHS Trust launched the Centre for Healthcare Technologies. The event was opened by Sir David Greenaway (Vice Chancellor, The University of Nottingham) and Peter Homa (Chief Executive, Nottingham University Hospitals NHS Trust). The programme for the day consisted of a series of presentations from MHRA, NICE, industry, funders, Nottingham academics and clinicians. Dr Joel Segal, PI of one of the feasibility studies presented the findings of the study in a presentation, "3D Printing Human Noses: An Engineering Perspective".
Year(s) Of Engagement Activity 2016
URL http://www.healthcaretechnologies.ac.uk/events/index.aspx
 
Description Distinguished Address - Bristol October 2016 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Industry/Business
Results and Impact Dr Wendy Phillips presented the work of RiHN at the Distinguished Address Series (DA), Bristol in October 2016. Dr Phillips's presentation focused on training and skills and precededan adress by Mark Stewart, General Manager and HR Director, Airbus. The DA Series of free public lectures brings top level business leaders to Bristol and is hosted by the University of West of England in conjunction with the Institute of Directors, the Bristol Post, The Chartered Management Institute,Bristol Junior Chamber, Institute of Chartered Accountants in England and Wales, Association of Chartered and Certified Accountants, Bristol City Council, CBI South West, Business West, West of England Local Enterprise partnerships and the NAtional Federation of Self-Employed and Small businesses Ltd. More than 150 people attended with representatives from local businesses and industry, public sector organisations such as NHS, MoD and Local Government, third sector organisations, undergraduate and postgraduate students. Dr Phillips's presentation stimulated discussion and questions relating to RDM and resulted in inreased interest in RiHN as evidenced by follow-up e-mails, increased Twitter and LinkedIn activity.
Year(s) Of Engagement Activity 2016
URL http://www1.uwe.ac.uk/whatson/bristoldaseries/previoustalks/markstewart.aspx
 
Description Distributed Manufacturing Workshop, September 2015, University of Cambridge, IfM 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Study participants or study members
Results and Impact Workshop held at Institute for Manufacturing, University of Cambridge to map the current state of the art, current research plans and remaining gaps in our knowledge which are not being addressed with respect to redistributed manufacturing. The event had representation from all the EPSRC RDM networks and other UK and Indian with an interest in RDM. The event aimed, through the sharing of activities, to identify opportunities for collaboration both within the UK and potentially with India.
Year(s) Of Engagement Activity 2015
 
Description EPSRC Centre for Innovative Manufacturing in Regenerative Medicine Closing Conference and Workshop, January 2016, Cambridge, UK 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Dr Joel Segal, PI of one of the feasibility studies presented at the EPSRC Centre for Innovative Manufacturing in Regenerative Medicine Closing Conference and Workshop, January 2016, Cambridge, UK. Dr Segal presented the findings of the feasibility study in a presentation: "Bioprinting - progress and opportunities"
Year(s) Of Engagement Activity 2016
 
Description EurOMA 2016 Special Session, Trondheim, Norway 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Study participants or study members
Results and Impact The RiHN team led a special stream on the topic of Redistributed Manufacturing (RDM) European Operations Management Association (EurOMA) conference, held in Trondheim, Norway on June 2016. This special stream on RDM invited Operations Management scholars and practitioners to explore key issues affecting the realisation of RDM, such as understanding operational risks, supply chain resilience and reconfiguration, how intellectual property or other legal and regulatory issues will be managed, modelling financial impact scenarios, requirements and resource factors, and evidencing contribution to competitiveness, health or environment. The session supported presentations of real world case examples, particularly where lessons can be drawn for wider consideration.
Year(s) Of Engagement Activity 2016
URL http://www.euroma2016.org/special-sessions/#session2
 
Description European Medicines Agency consultation 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact The Centre has been active within the European Regulatory area through an initiative with EATRIS. In 2015 a joint meeting was held with the European Medicines Agency at Canary Wharf with the objective of introducing the Centre/EATRIS initiative in distributed manufacturing. an invitation has been extended for Loughborough to put key research questions to the Committee for Advanced Therapeutics in 2016 which could result in cooperative effort to establish a collaborative program of work in EMA priority areas.
Year(s) Of Engagement Activity 2015
 
Description Final workshop on Re-distributed Manufacturing in Healthcare 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact This was the final workshop for the Re-distributed Manufacturing in Healthcare Network (RiHN) that ran for Caledar Years 2016 and 2017. The workshop presented the findings from the feasibility studies, prompted debate about the significance and onward work and formed the final input before drafting the report that was issued at the end of 2017.
Year(s) Of Engagement Activity 2017
URL https://www.linkedin.com/feed/update/urn:li:activity:6344476344876875776/
 
Description Future of Pharmaceutical Supply Chains 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact This one-day knowledge exchange event brought together industry and academic experts to map the future challenges facing pharmaceutical supply chains, paying particular attention to how redistributed manufacturing (RDM) techniques, such as 3D printing, can enhance the resilience and responsiveness of pharmaceutical supply chains.

The event began with key note speeches from industry leaders and senior academics including: Dr. Wendy Phillips, the Network Director for the Redistributed Manufacturing in Healthcare Network (RiHN; Neil Baker, the Head of the Medicines Manufacturing Industry (MMIP) partnership and Pfizer Senior Director; Dr. Jagjit Srai from the Institute of Manufacturing at the University of Cambridge and: Prof. Ricky Wildman from the EPSRC Centre of Innovative Manufacturing in Additive Manufacturing.

Following the speeches, participants were split into small groups to discuss the current and future challenges faced by pharma supply chains and to develop potential solutions to overcome these challenges. Participants benefited from joining a network of healthcare and pharmaceutical professionals and received research outputs from the event.
Year(s) Of Engagement Activity 2016
URL http://rihn.org.uk/blog/future-pharmaceutical-supply-chains-knowledge-exchange-event/
 
Description International Symposium (Shanghai) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact International Symposium on Smart and Optimal Manufacturing in the Process Industry at ECUST (East China University of Science and Technology, Shanghai, China
19-21 April, 2017).
Organizers
- East China University of Science and Technology, China
- University College London, United Kingdom
- The University of Sheffield, United Kingdom
Supporters
- Chinese Academy of Engineering, China
- Royal Academy of Engineering, United Kingdom (with whom I was the invited delegate on advanced healthcare engineering and was able to describe the motivations and findings of my Fellowship work at Loughborough)
Sponsors
- Key Laboratory of Advanced Control and Optimization for Chemical Processes, Ministry of Education, China
- State Key Laboratory of Chemical Engineering, China
Year(s) Of Engagement Activity 2017
URL http://www.sciencedirect.com/journal/engineering/vol/3/issue/2
 
Description NC3Rs workshop: Bioprinting for more predictive efficacy and safety testing (Feasibility Study 5) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation by one of the feasibility studies at the NC3Rs workshop: Bioprinting for more predictive efficacy and safety testing, December 2015, London, UK. Dr Joel Segal, PI of one of the feasibility studies presented findings of the study during a talk on: "What gaps and opportunities exist to advance the uptake of bioprinting in industry and how do we capitalise on this?". The NC3Rs, Innovate UK and the Knowledge Transfer Network jointly hosted the workshop in order to advance the development and application of bioprinting approaches for improved efficacy and safety testing of drugs and other chemicals.
Year(s) Of Engagement Activity 2015
URL https://www.nc3rs.org.uk/events/bioprinting-for-more-predictive-efficacy-and-safety-testing
 
Description Navigating Regulatory Requirements for Redistributed Manufacturing in Healthcare 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact On 14 October 2016 RiHNto host an event on healthcare regulations. The aim of the event wasbe to review and advance the understanding of regulatory requirements affecting distributed models of manufacturing in healthcare. Expert speakers included representatives from MHRA, BSI Group, EATRIS and the LGC Group
Year(s) Of Engagement Activity 2016
URL http://rihn.org.uk/?s=navigating
 
Description Post Brexit how do we define UK regulatory framework for healthcare? 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Press release to draw attention to how Brexit may impact upon UK healthcare regulation and manufacturing and to draw attention to the Regulatory event being hosted by RiHN at the Medical research Council London in October 2016. The release drew more attention to the project in terms of website visits, twitter feeds and also sign-up to the regulatory event
Year(s) Of Engagement Activity 2016
URL https://info.uwe.ac.uk/news/uwenews/news.aspx?id=3473
 
Description Presentation of the PeePod and the new RiPod to VoiceNORTH, April 2016 (Feasibility study 3) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Patients, carers and/or patient groups
Results and Impact Dr Alison Bray, a researcher working on e of the feasibility prepared a patient engagement session where the subject of one of the feasibility studies, the PeePod, was presented to VoiceNORTH, a group of lay people and patients. These interactions have informed many of the feasibility study's research team's views, particularly the suitability of RDM manufacture for home use.
Year(s) Of Engagement Activity 2016
 
Description Press release 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact The press release sparked interest and resulted in increased traffic to the project's website. Also individuals were interested in attending future workshops and participating inn the research

After the press release individuals asked if they could attend our sandpit events
Year(s) Of Engagement Activity 2015
URL http://www.buildingbetterhealthcare.co.uk/news/article_page/Tripartite_collaboration_results_in_fund...
 
Description RDM Cross Network Event, Cranfield University, Jan 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact The final cross network event hosted by the RECODE network at Cranfield University. The event was attended by representatives from each of the EPSRC networks, the EPSRC ESRC and members of the Working Panel. Each network presented a five minute elevator pitch covering the key learnings from their receptive network, areas for continued research, identification of future research partners, potential sources of future funding,the future of each respective network. Following the elevator pitches, the group discussed the possible impacts of RDM. In breakout groups, the participants considered what redistributed manufacturing might look like in the future - each group producing a "Manifesto". The event concluded with a discussion around the identification of themes and priorities for future research.
Year(s) Of Engagement Activity 2017
 
Description RDM Cross Network Event, Oxford 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact Cross network event hosted by the Local Nexus Network, University of Oxford in September 2016. The event was attended by representatives from each of the EPSRC RDM networks, the EPSRC and ESRC and members or the Working Panel. Each RDM network presented on the progress of their individual networks. The first half of the event focused on identifying common essential attributes of RDM with to ascertain whether a common definition for RDM can be achieved or whether it might be more appropriate to have a set of different definitions that reflect the different perspectives of various sectors and groups? Over a working lunch the participants discussed whether RDM can be become a part of the future of manufacturing. The final session consider how to realise and research RDM.
Year(s) Of Engagement Activity 2016
 
Description RDM Cross network event - Cambridge 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact The second cross-network event for all the RDM networks funded by the EPSRC, held in January 2016 at the Institute for Manufacturing, University of Cambridge. The event was attended by representatives from each of the RDM networks and there was representation from the EPSRC and the Working Panel. The meeting provided an opportunity for the networks to share their respective experiences in running the RDM networks. The meeting also involved a discussion led by Eujin Pei from Brunel University, centred around how 3D printing could play a role in localised, flexible, resilient and sustainable manufacturing.
Year(s) Of Engagement Activity 2016
 
Description RDM cross network Event - RCA London, October 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact The penultimate RDM cross network event held by the The Future Makespaces Network at the Royal College of Art, London in October 2016. The event was attended by representatives from each of the EPSRC RDM Networks, the EPSRC and ESRC and members of the working panel. The event involved 3 minute elevator pitch from each EPSRC RDM network on the future that each network's vision of RDM enables. The participants broke out into groups and mapped the technical ecosystem of each network in terms of the challenges and opportunties. Finally, the value chains of selected feasibility studies from each of the networks were mapped in terms of the current state of play and the future state of play should an RDM approach be implemented.
Year(s) Of Engagement Activity 2016
 
Description RDM cross network event - Cardiff 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact Cross network event held in April 2016 at Cardiff University. The vent had representatives from each of the EPSRC RDM Networks, the EPSRC and ESRC and the Working Panel. The event involved three short sessions on the topics of "Mechanisms for Distributed Collaboration", "Engagement with the Wider Community" and "RDM Emerging Themes".
Year(s) Of Engagement Activity 2016
 
Description RDM cross network event Bristol 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact This was the first cross network event and was hosted by RiHN at UWE Bristol in October 2015. There was representation from all the RDM networks funded by the EPSRC, members of the Working Panel, EPSRC and ESRC . The focus of the day was an update on the progress of each network followed by a round table discussion of how the networks could work together to create opportunities for collaboration and a session to identify pathways to impact.
Year(s) Of Engagement Activity 2015
 
Description Redistributed manufacturing in deployed operations workshop, Birmingham, Feb 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact This was a workshop led by the RiHN team but that had acquired additional funding from the EPSRC. RiHN had identified that, currently, the vake of RDM in healthcare lies in niche applications particularly in front-line services, most notably defence. RiHN had engaged with the Royal Centre for Defence medicine and developed a successful proposal to fund a workshop to scope out the research priorities for RDM in emergency and military medicine. Through road-mapping exercises the participants scope out key research packages which could be taken forward into larger scale research projects. The audience was composed of mainly defence staff, particulalry nurses, surgeons and clinicians.
Year(s) Of Engagement Activity 2017
URL https://goo.gl/UsFbfc
 
Description RiHN LinkedIn Network 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact RiHN has established a LinkedIn Group which comprises a multi-disciplinary network including academics, practitioners and industry representatives providing an online forum to define the challenges of realising Re-Distributed Manufacture (RDM) in healthcare.
Year(s) Of Engagement Activity 2015,2016,2017
URL https://www.linkedin.com/groups/8238989
 
Description RiHN website 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact The RiHN Website (www.rihn.org.uk) has been set up to inform interested parties of the Network's activities and outputs. Via RiHN's social media strategy the network coordinator has ensured that all activities of the network, feasibility studies and organisations relevant to RDM in manufacturing are communicated through the website and outputs and specifically produced materials such as videos are uploaded to the site. The website provides an overview of the feasibility studies funded by the project all of the feasibility studies have been required to produce a two minute summary video of their topic and signpost their activities as a condition of receiving network funding and these have been added to the website. The Website has expanded RiHN's outreach as evidenced by the web traffic and the request for further information and network membership appications.

The website is updated regularly and informs network members of and interested individuals of developments in the area of RDM in healthcare. Through the website, those who would like to know more about the RiHN's work can access information and can join the network.

The RiHN website is evolving into a repository of expertise with the potential to persist beyond the life of the network
Year(s) Of Engagement Activity 2015,2016,2017
URL http://www.rihn.org.uk
 
Description Round Table discussion on RDM in healthcare - policy recommendations 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact 10 experts related to the field of redistributed manufacturing were brought together for a round table discussion to develop policy recommendations for the development of redistributed manufacturing in the UK, with a particular focus on healthcare.
Year(s) Of Engagement Activity 2017
URL https://www.researchgate.net/project/Redistributed-Manufacturing-in-Healthcare-RiHN
 
Description Supply Chain Special Interest Group (SIG): RiHN Feasibility Study Launch 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact In November 2015 the RiHN team hosted a Special Interest Group in partnership with Medilink . Those who attended had the opportunity to engage with researchers from various institutions leading cutting edge feasibility studies that have the potential to radically transform patient care and medical supply chains.

The event started with a welcome from Dr Steve Langron from Lime Associates (representing the Medilink EM SIG) and RiHN Network Director Dr Wendy Phillips. A key note presentation was delivered by Professor Nick Rich of Swansea University. This was followed by presentations by the five feasibility studies supported by RiHN
Year(s) Of Engagement Activity 2015
URL http://rihn.org.uk/blog/supply-chain-special-interest-group-sig-redistributed-manufacturing-in-healt...
 
Description Targeted Healthcare Production: Where is it needed most?' (Bristol) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact The RiHN launch event and 1st Sandpit Workshop was held on the 26th March 2015 at the Engine Shed in Bristol. The workshops provided an expert forum from which stakeholders of healthcare R&D debated the potential impact of Redistributed Manufacturing (RDM). Event speakers included Sir Mark Walport, Dr Mark Claydon-Smith, Dr Wendy Phillips, Professor Andrew Webster and Professor Nick Medcalf. Between them, the speakers outlined the rationale and importance of the network, as well as political drivers, strategic benefits and technical issues related to the implementation of RDM in healthcare.The Sandpit Workshops involved two distinct activity sessions, (I) the mapping and identification of priority topics, and (II) critical analysis of topics leading towards potential feasibility studies.
Year(s) Of Engagement Activity 2015
URL http://rihn.org.uk/about/redistributed-manufacturing-research/
 
Description Targeted healthcare production: Where is it needed most (Nottingham) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact The 2nd Sandpit Workshop was held 28th April 2015 at Nottingham University. The workshops provided an expert forum from which stakeholders of healthcare R&D debated the potential impact of Redistributed Manufacturing (RDM). Event speakers included Sir Mark Walport, Dr Mark Claydon-Smith, Dr Wendy Phillips, Professor Andrew Webster and Professor Nick Medcalf. Between them, the speakers outlined the rationale and importance of the network, as well as political drivers, strategic benefits and technical issues related to the implementation of RDM in healthcare. The Sandpit Workshops involved two distinct activity sessions, (I) the mapping and identification of priority topics, and (II) critical analysis of topics leading towards potential feasibility studies.
Year(s) Of Engagement Activity 2015
URL http://rihn.org.uk/about/redistributed-manufacturing-research/
 
Description Workshop on Collaborative Enterprise Networking for The Midlands 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact 18 delegates comprising representatives of regional NHS Trusts and regenerative medicine research groups attended a workshop at Kegworth to explore the feasibility of a collaborative enterprise to accelerate the translation of Advanced Therapeutic Medicinal Products (ATMPs).

Goal
To deliver ATMPs to the Midlands, economically and in a resilient and agile manner and in a manner that fits with NHS practice at the time.

Objectives
• System to cope with high and low volume production
• System must use current infrastructure
• Single Quality System with minimum safe checking [consistent with patient need - Editor comment on writeup]
• Enables participation of SMEs
• Enables sub-contracting of operations
Year(s) Of Engagement Activity 2016