Discrete computational modelling of twin screw granulation
Lead Research Organisation:
University of Sheffield
Department Name: Chemical & Biological Engineering
Abstract
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Publications
Ai Q
(2018)
Twin screw granulation: An evaluation of using micronized lactose as a solid binder
in Chemical Engineering Research and Design
AlAlaween W
(2020)
An interpretable fuzzy logic based data-driven model for the twin screw granulation process
in Powder Technology
AlAlaween WH
(2018)
Transparent predictive modelling of the twin screw granulation process using a compensated interval type-2 fuzzy system.
in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Khorsheed B
(2019)
Twin-screw granulation: Understanding the mechanical properties from powder to tablets
in Powder Technology
| Description | This grant supported a project led by Prof Mike Adams at the University of Birmingham - please see the outcomes reported under grant ref EP/M02959X/1 |
| Exploitation Route | Pubilcations |
| Sectors | Pharmaceuticals and Medical Biotechnology |
| Description | Sheffield-Purdue collaboration on granulation modelling |
| Organisation | Purdue University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | We helped develop the framework for granulation compartment model and performed validation experiments in the laboratory at Sheffield. |
| Collaborator Contribution | Through the grant, Professor Litster from Purdue University was a visiting research scientist at Sheffield to establish an ongoing collaboration. One of Professor Litster's PhD students, Nathan Davis, visited Sheffield for three months in October-December 2013 at Purdue's expense and continues to work with Sheffield staff on developing DEM models for granulation. Another Purdue student, Dan Pohlman, has implemented the model in the commercial software, gSOLIDS> |
| Impact | Co-authored conference presentations and paper (see publication list) with further outputs to come. A new granulation model implemented in the commercial software, gSOLIDS. |
| Start Year | 2013 |