Medical Technologies Innovation and Knowledge Centre Phase 2 Regenerative Devices
Lead Research Organisation:
University of Leeds
Department Name: Mechanical Engineering
Abstract
Regenerative devices (scaffolds, biomaterials and interventions) which can repair and regenerate tissues using the patients` own cells, can be translated into successful clinical products and deliver patient benefit at much lower cost and risk and in shorter timescales then other regenerative therapies such as culture expanded cell therapies or molecular (drug) therapies. It is estimated that the global market for regenerative devices will grow to £50bn by 2020 and this offers a real opportunity to grow a £1bn per year industry in the UK in this field.
The UK has genuine research strengths in the areas of biomaterials and tissue engineering, musculoskeletal mechanics (prioritised by EPSRC) and regenerative medicine. Regenerative medicine is one of the eight great technologies prioritised across the Research Councils. Research discoveries, new knowledge, outputs and outcomes are often not ready for uptake by industry to take forward through product development to the market and patient benefit. New technologies need to be advanced and de-risked. The clinical needs, potential products and markets need to be defined in order to make them attractive for investment, product development and clinical trials by industry.
In the Medical Technologies Innovation and Knowledge Centre (MTIKC) Phase 1, working with industry and clinical partners, we have developed a professional innovation team and a unique innovation and translation process, creating a multidisciplinary research and innovation ecosystem. We have successfully identified research outcomes and new knowledge and created, advanced and translated technology across the innovation valley of death, enabling successful investment (over £100m) by industry and the private sector in new product development. Some products have already progressed to clinical trials and commercialisation and are realising patient benefits. We have established a continuous innovation pipeline of over fifty proofs of concept technology projects.
Over the next five years in MTIKC Phase 2, we will address unmet clinical needs and market opportunities in wound repair, cardiovascular repair, musculoskeletal tissue repair, maxillofacial reconstruction, dental reconstruction and general surgery and diversify our research supply chain to over ten other Universities. We will support 150 collaborative projects with industry and initiate forty new industry inspired and academically led proof of concept projects, which are predicted to lead to a further £100m investment by the private sector in subsequent product development. This will enable a sustainable research and product development pipeline to be established in the UK which will support a £1bn / year industry in regenerative devices beyond 2020.
The UK has genuine research strengths in the areas of biomaterials and tissue engineering, musculoskeletal mechanics (prioritised by EPSRC) and regenerative medicine. Regenerative medicine is one of the eight great technologies prioritised across the Research Councils. Research discoveries, new knowledge, outputs and outcomes are often not ready for uptake by industry to take forward through product development to the market and patient benefit. New technologies need to be advanced and de-risked. The clinical needs, potential products and markets need to be defined in order to make them attractive for investment, product development and clinical trials by industry.
In the Medical Technologies Innovation and Knowledge Centre (MTIKC) Phase 1, working with industry and clinical partners, we have developed a professional innovation team and a unique innovation and translation process, creating a multidisciplinary research and innovation ecosystem. We have successfully identified research outcomes and new knowledge and created, advanced and translated technology across the innovation valley of death, enabling successful investment (over £100m) by industry and the private sector in new product development. Some products have already progressed to clinical trials and commercialisation and are realising patient benefits. We have established a continuous innovation pipeline of over fifty proofs of concept technology projects.
Over the next five years in MTIKC Phase 2, we will address unmet clinical needs and market opportunities in wound repair, cardiovascular repair, musculoskeletal tissue repair, maxillofacial reconstruction, dental reconstruction and general surgery and diversify our research supply chain to over ten other Universities. We will support 150 collaborative projects with industry and initiate forty new industry inspired and academically led proof of concept projects, which are predicted to lead to a further £100m investment by the private sector in subsequent product development. This will enable a sustainable research and product development pipeline to be established in the UK which will support a £1bn / year industry in regenerative devices beyond 2020.
Planned Impact
Economic impact: MTIKC will support the development of a £1bn /year industry in UK, addressing an emergent global market in regenerative devices estimated at £50bn /year. MTIKC will take research outputs at technology readiness level (TRL) 2 and translate them across the innovation valley of death at TRLs 3 and 4. This will be achieved by advancing and de-risking the technology, and defining clinical needs, products, markets and private sector partners to invest in new product development at TRLs 5 to 9 and translate to clinical trials and market. To date MTIKC Phase 1 has demonstrated over £100m direct and indirect private sector investment in the private sector and MTIKC Phase 2 will lead to public and private sector investments in R & D in the UK to support the development and sustainability of a £1bn industry in regenerative devices. The pathway to economic impact includes a strategically focused research and innovation ecosystem based on more than ten Universities in the UK, a dedicated professional innovation team, strong collaborative networks with academia, industry, investors, clinicians, regulators, and NHS and Government agencies. Translation of technology involves a strong multidisciplinary research supply chain, a robust and validated stage-gated innovation process and industry inspired and academically led proof of concept projects, support for patenting, licensing creation, development of spinouts and support for industry collaborations and partnering.
Clinical patient and societal benefits: Society, patients and healthcare providers will benefit from more effective, reliable and cost effective regenerative devices and interventions which address the needs of stratified patient populations with greater levels of precision. Technologies and products supported in the early phases of MTIKC Phase 1, such as self-assembling peptides, acellular human donor tissues and biological scaffolds are already in the market or clinical trials. Enabling technologies- simulation technologies are being used extensively in product development programmes and introduced as international standards. Other new products, technologies and services which will flow from MTIKC by 2020 and beyond.
Transfer of highly trained innovative people and high level skills: Translation and innovation of emergent technologies needs the development and transfer highly skilled people. Technology and scientific training plus innovation and broader skills training is delivered by MTIKC to PhDs through CDTs, to PDRAs through career development programmes and to the wider academic community through specialised workshops. Greater than 75% of our doctoral researchers progress to careers outside academia, with a strong flow of people to our collaborators. Effective collaborative working with industry, either through 300 collaborative projects and 90 POC projects allows the transfer of essential knowledge and skills from university to industry partners. This is supplemented by specialised consultancy advice and access to specialist equipment and skills to industry.
Creation of a more effective pathway for clinical innovation and translation: MTIKC is working with LTHT and LMBRU (see letters of support) on projects to support clinical translation by engaging and training clinical academics and NHS clinicians in early translation. These are important skills and experiences not usually available in the NHS.
Public and patient engagement and influencing policy: This is undertaken collaboratively with NHS, LTHT and LMBRU through their active PPI group. Direct activities with the public are undertaken by the university, with activities in local schools, local and national science fairs. The investigators are also active nationally in both RAEng and EPSRC and regionally in LEP in advising and acting as advocates for the importance of science and innovation.
Clinical patient and societal benefits: Society, patients and healthcare providers will benefit from more effective, reliable and cost effective regenerative devices and interventions which address the needs of stratified patient populations with greater levels of precision. Technologies and products supported in the early phases of MTIKC Phase 1, such as self-assembling peptides, acellular human donor tissues and biological scaffolds are already in the market or clinical trials. Enabling technologies- simulation technologies are being used extensively in product development programmes and introduced as international standards. Other new products, technologies and services which will flow from MTIKC by 2020 and beyond.
Transfer of highly trained innovative people and high level skills: Translation and innovation of emergent technologies needs the development and transfer highly skilled people. Technology and scientific training plus innovation and broader skills training is delivered by MTIKC to PhDs through CDTs, to PDRAs through career development programmes and to the wider academic community through specialised workshops. Greater than 75% of our doctoral researchers progress to careers outside academia, with a strong flow of people to our collaborators. Effective collaborative working with industry, either through 300 collaborative projects and 90 POC projects allows the transfer of essential knowledge and skills from university to industry partners. This is supplemented by specialised consultancy advice and access to specialist equipment and skills to industry.
Creation of a more effective pathway for clinical innovation and translation: MTIKC is working with LTHT and LMBRU (see letters of support) on projects to support clinical translation by engaging and training clinical academics and NHS clinicians in early translation. These are important skills and experiences not usually available in the NHS.
Public and patient engagement and influencing policy: This is undertaken collaboratively with NHS, LTHT and LMBRU through their active PPI group. Direct activities with the public are undertaken by the university, with activities in local schools, local and national science fairs. The investigators are also active nationally in both RAEng and EPSRC and regionally in LEP in advising and acting as advocates for the importance of science and innovation.
Organisations
- University of Leeds (Lead Research Organisation)
- Edwards Lifesciences Corporation (Collaboration)
- Xiros Ltd (Collaboration)
- Corin Group PLC (Collaboration)
- North American Science Associates Inc (Collaboration)
- Medacta (Collaboration)
- NHS Blood and Transplant (NHSBT) (Collaboration)
- UNIVERSITY OF SOUTHAMPTON (Collaboration)
- Sheffield Children's Hospital (Collaboration)
- Neotherix Ltd (Collaboration)
- ZINC VENTURES LIMITED (Collaboration)
- Ceramisys (Collaboration)
- Invibio (Collaboration)
- DePuy Synthes (Collaboration)
- Manchester BIOGEL (Collaboration)
- Leeds Teaching Hospitals NHS Trust (Collaboration, Project Partner)
- IPB University (Collaboration)
- Simulation Solutions (Collaboration)
- Cytori Ltd (Collaboration)
- Credentis (Collaboration)
- Cardiff University (Collaboration)
- Tissue Regenix Ltd (Collaboration)
- Vascutek Ltd (Collaboration)
- University College London (Collaboration)
- VU University Medical Center (Collaboration)
- Collagen Solutions (Collaboration)
- NuVision (Collaboration)
- Renishaw (United Kingdom) (Collaboration)
- Depuy International (Collaboration)
- PBC Biomed (Collaboration)
- Sheffield Teaching Hospitals NHS Foundation Trust (Collaboration)
- Tissue Regenix PLC (Project Partner)
- University of Bradford (Project Partner)
- Neotherix (United Kingdom) (Project Partner)
- University College London (Project Partner)
- University of Liverpool (Project Partner)
- Newcastle University (Project Partner)
- Johnson & Johnson (United Kingdom) (Project Partner)
- Quantum Imaging ltd (Project Partner)
- Medicines & Healthcare pdts Reg Acy MHRA (Project Partner)
- Credentis (Switzerland) (Project Partner)
- University of Nottingham (Project Partner)
- HealthTech and Medicines KTN (Project Partner)
- Victrex (United Kingdom) (Project Partner)
- Relitect Ltd. (Project Partner)
- University of York (Project Partner)
- University of Manchester (Project Partner)
- University of Sheffield (Project Partner)
- NHS Blood and Transplant (Project Partner)
- Xiros (United Kingdom) (Project Partner)
- Simpleware (United Kingdom) (Project Partner)
- Simulation Solutions (United Kingdom) (Project Partner)
- University of Cambridge (Project Partner)
- IP Group (United Kingdom) (Project Partner)
- University of East Anglia (Project Partner)
Publications
Abdelgaied A
(2018)
A comprehensive combined experimental and computational framework for pre-clinical wear simulation of total knee replacements.
in Journal of the mechanical behavior of biomedical materials
Abdelgaied A
(2015)
Comparison of the biomechanical tensile and compressive properties of decellularised and natural porcine meniscus.
in Journal of biomechanics
Abdelgaied A
(2017)
A comparison between electromechanical and pneumatic-controlled knee simulators for the investigation of wear of total knee replacements.
in Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
Ahmed I
(2019)
Developing Unique Geometries of Phosphate-Based Glasses and their Prospective Biomedical Applications
in Johnson Matthey Technology Review
Al-Hajjar M
(2019)
Combined wear and ageing of ceramic-on-ceramic bearings in total hip replacement under edge loading conditions.
in Journal of the mechanical behavior of biomedical materials
Al-Hajjar M
(2017)
Wear of composite ceramics in mixed-material combinations in total hip replacement under adverse edge loading conditions.
in Journal of biomedical materials research. Part B, Applied biomaterials
Aldridge A
(2017)
Development and characterisation of a large diameter decellularised vascular allograft
in Cell and Tissue Banking
Ali M
(2016)
Influence of hip joint simulator design and mechanics on the wear and creep of metal-on-polyethylene bearings.
in Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
| Description | Our purpose as the EPSRC national centre for medical technology innovation, is to advance multidisciplinary science and medical technologies, accelerate innovation, reduce technical, regulatory and commercial uncertainty, increase the downstream investment potential in the development of medical devices and products, deliver economic benefits and future growth in combination with improving the health and wellbeing of an ageing population - fifty active years after fifty. We have a specific focus on regenerative technologies and devices and the related enabling and companion medical technologies. We have an emphasis on medical technology and devices for musculoskeletal disease, dental care, wound care and cardiovascular disease. In thirteen years since its creation in 2009 (IKC phase one and phase 2) the MTIKC has developed a distinctive system which integrates and connects all of the following activities to deliver economic and social impact at the end of the value chain. Concentration of internationally excellent underpinning research and knowledge creation. £146m new research funding, 3066 research papers, 51 patents/licences, training and development of graduates and PhDs and PDRAs, progressing to industry healthcare and academia, 164 doctoral researchers and 196 masters graduates A centre with 62 industry/clinical research partners and an extended group of 202 user partners signed formal agreements, a wider network of 504 members. A multi professional, multidisciplinary technology innovation management team and process, with experience of research and development from industry and academia. A portfolio of 267 proof of concept, technology development and demonstration projects of which 84 have progressed beyond TRL 4 and to product development. Alternative sources of public funding for technology advancement, innovation projects and innovation management from, Versus Arthritis, HEFCE, UKRI Research England: £10m. Downstream private sector investment into the private sector for product development, evaluation manufacturing: £160m in start-ups and a further £50m into existing industry. A rapidly emerging clinical innovation and evaluation infrastructure in Leeds City Region. Spin out companies: Seven new spinouts or start ups. New product development and manufacturing facilities and activities including Tissue Regenix, DePuy Synthes, Invibio, NHS Blood and Transplant, Creavo and Credentis. Provided support for enabling industries such as Simulation Solutions and led the development of new international standards. |
| Exploitation Route | In thirteen years since its creation in 2009 (IKC phase one and phase two): The MTIKC has developed a distinctive system which integrates and connects all of the following activities to deliver economic and social impact at the end of the value chain: Concentration of internationally excellent underpinning research and knowledge creation. £146m new research funding, over 3000 research papers, 51 patents/licences. Training and develop of graduates and PhDs and PDRAs, progressing to industry healthcare and academia, 164 doctoral researchers and 196 masters graduates. The centre has 62 industry/clinical research partners and an extended group of 218 user partners signed formal agreements, a wider network of 504 members. A multi professional, multidisciplinary technology innovation management team and process, with experience of research and development from industry and academia. A portfolio of 267 proof of concept, technology development and demonstration projects of which 84 have progressed beyond TRL 4 and to product development. Alternative sources of public funding for technology advancement, innovation projects and innovation management from, ARUK, HEFCE, UKRI Research England £10m Downstream private sector investment into the private sector for product development, evaluation manufacturing, £160m in start-ups and a further £50m into existing industry. A rapidly emerging clinical innovation and evaluation infrastructure in Leeds City Region. Spin out companies: seven new spinouts or start ups created. Established new product development and manufacturing facilities and activities including Tissue Regenix, DePuy Synthes, Invibio, NHS Blood and Transplant, Creavo and Credentis. Provided support for enabling industries such as Simulation Solutions and led the development of new international standards. |
| Sectors | Healthcare,Manufacturing, including Industrial Biotechology |
| URL | http://imbe.leeds.ac.uk |
| Description | In fourteen years since its creation in 2009 (IKC phase one and phase 2), the Medical Technology IKC has developed a distinctive system which integrates and connects the following activities throughout the innovation cycle to deliver economic value and social impact at the end of the value chain. It has established a concentration of internationally excellent underpinning research and knowledge creation: - £146m new research funding - over 3000 research papers - 51 patents/licences; training and development of graduates and PhDs and PDRAs, progressing to industry healthcare and academia including 164 doctoral researchers and 196 masters graduates. - grown 62 industry/clinical research partners and an extended group of 218 user partners with signed formal agreements and established a wider network of 504 members. -developed a multi professional, multidisciplinary technology innovation management team and process, with experience of research and development from industry and academia. - a portfolio of 267 proof of concept, technology development and demonstration projects of which 84 have progressed beyond Technology Readiness Level 4 and to product development. - alternative sources of public funding for technology advancement, innovation projects and innovation management from, Versus Arthritis, HEFCE, UKRI Research England. - £10m Downstream private sector investment into the private sector for product development, £160m in start-ups and a further £50m into existing industry. - a clinical innovation and evaluation infrastructure in Leeds City Region - spin out companies with 7 new spin outs or start ups created. - new product development and manufacturing facilities and activities including Tissue Regenix, DePuy Synthes, Invibio, NHS Blood and Transplant, Creavo and Credentis More recently during MTIKC phase 2, since July 2015 the MTIKC has: - generated over £48m new research funding to sustain the pipeline of new knowledge creation. - trained 115 doctoral students and 161 masters students. - collaborated with 50 national and international research partners. Collaborated with 218 user organisations. - engaged with 62 business partners directly involved in collaborative research and innovation projects, of which 22 are SMEs. - conducted 319 different discrete activities and functions held with representative groups to influence the direction or content of research and innovation. - undertaken 47 public or patient engagement events. - generated nine new patent families and two new spin out companies. - undertaken 100 proof of concept or demonstration projects with partners. - successfully completed 23 proofs of concept projects which are delivering commercial value to partners as demonstrated by advancement to TRL5 and beyond; private sector industry has invested a further £62m plus into downstream R&D or new manufacturing facilities. |
| First Year Of Impact | 2015 |
| Sector | Healthcare,Manufacturing, including Industrial Biotechology |
| Impact Types | Societal,Economic |
| Description | Chair of British Standards (BSI) national committee (CH150/04) for Bone and Joint Replacements |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Development of state of the art International Standards, to improve the safety and reliability of joint replacements |
| Description | Chair of ISO TC150/SC4 Bone and Joint Replacements |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Impact | New international standards published, including a test method developed at the University of Leeds (ISO14242-4). |
| Description | IKC POC081 - Innovate UK Intracellular Working Group |
| Geographic Reach | Europe |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | IKC POC081 Member of the Advanced Therapeutic Working Group from March 2021 |
| Geographic Reach | Europe |
| Policy Influence Type | Membership of a guideline committee |
| Description | LCR BIG Panel |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Membership of local economic partnership Leeds city region , west Yorkshire combined authority business Innovation growth Panel - special advisor on research innovation Universities |
| Description | Med ical technology science and innovation audit |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Leadership of Medical Technology science an dInnovation audit, Leeds City region Plus |
| Description | Presented 'provocation' and participated in Wellcome Health Exchange - Wellcome Trust discussion on healthy aging research chaired by Eliza Manningham-Buller (Ruth Wilcox) |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | UKRI Healthcare technologies workshop (21 Feb 2022) |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | Versus Arthritis Advisory group |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | international standards committee chair |
| Geographic Reach | Asia |
| Policy Influence Type | Membership of a guideline committee |
| Impact | international pre clinical testing standards |
| Description | A Rapid Integrated Tendon Repair System (RITRS) |
| Amount | £74,986 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2021 |
| End | 02/2022 |
| Description | ARUK |
| Amount | £700,000 (GBP) |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2016 |
| End | 09/2021 |
| Description | Apollonia - the next level of dental care |
| Amount | £754,741 (GBP) |
| Funding ID | 133651 |
| Organisation | Innovate UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2018 |
| End | 10/2020 |
| Description | August 2 SNIPER: Injectable Spinal Fusion Grow Med Tech PoF £20,000 (POC057 Sammon Le Maitre SHU) |
| Amount | £20,000 (GBP) |
| Organisation | Grow MedTech |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 08/2019 |
| End | 01/2020 |
| Description | British Council Newton Fund |
| Amount | £116,000 (GBP) |
| Organisation | British Council |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2020 |
| End | 02/2021 |
| Description | CCTMIH Manufacture of Future Fibrous Products Research Fellowship |
| Amount | £250,000 (GBP) |
| Organisation | University of Leeds |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 03/2019 |
| End | 03/2021 |
| Description | Capital equipment CDT |
| Amount | £240,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2015 |
| End | 04/2019 |
| Description | Capital equipment hip and knee simulators |
| Amount | £920,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2015 |
| End | 04/2020 |
| Description | Catalyst Medical Technologies |
| Amount | £3,000,000 (GBP) |
| Organisation | Higher Education Funding Council for England |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 10/2018 |
| Description | Chancellor's Fellow £30k (SHU funding) to support manufacturing of sol-gel based 3D matrices for bone regeneration. (POC057 Sammon Le Maitre SHU) |
| Amount | £30,000 (GBP) |
| Organisation | Sheffield Hallam University |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 01/2019 |
| End | 07/2019 |
| Description | Clothworkers CASE award - Non-tissue staining photodynamically-active fibres for antibiotic-free infection control in chronic wounds |
| Amount | £26,000 (GBP) |
| Organisation | The Clothworkers' Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2019 |
| End | 09/2022 |
| Description | Clothworkers Foundation/UoL - CCTMIH Equipment |
| Amount | £500,000 (GBP) |
| Organisation | University of Leeds |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 12/2018 |
| End | 12/2019 |
| Description | Depuy |
| Amount | £300,000 (GBP) |
| Organisation | Depuy International |
| Sector | Private |
| Country | United Kingdom |
| Start | 01/2016 |
| End | 01/2017 |
| Description | Development of Next Generations Synergistic Antibiofilm Treatments for Wounds. National Biofilms Innovation Centre |
| Amount | £26,000 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2019 |
| End | 12/2019 |
| Description | Development of an intelligent robotic knee device to support and monitor rehabilitation therapy for the ageing population with knee osteoarthritis |
| Amount | £50,295 (GBP) |
| Funding ID | ES/W006499/1 |
| Organisation | Economic and Social Research Council |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2021 |
| End | 08/2022 |
| Description | Dragons den style interview for investment from Sheffield Hallam University and secured £50k to broaden the scope of the research (POC057 Sammon Le Maitre SHU) |
| Amount | £50,000 (GBP) |
| Organisation | Sheffield Hallam University |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 01/2018 |
| End | 12/2018 |
| Description | EPSRC |
| Amount | £1,000,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2016 |
| End | 06/2022 |
| Description | EPSRC |
| Amount | £4,000,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2016 |
| End | 10/2021 |
| Description | EPSRC - VaxHub Thermostable Formulations |
| Amount | £192,000 (GBP) |
| Organisation | University of Leeds |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 05/2019 |
| End | 07/2020 |
| Description | EPSRC Network Plus - Redistributed Manufacturing in Deployed Medical Care (RiHN). Combining Orthobiologics, Antimicrobial and Angiogenic Properties for Rapid Treatment of Bone Repair in Deployed Settings |
| Amount | £50,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2021 |
| End | 09/2021 |
| Description | Enabling Individualised Surgical Treatment of Osteoarthritis |
| Amount | £1,246,813 (GBP) |
| Funding ID | EP/W003139/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2022 |
| End | 12/2025 |
| Description | FREEpHRI: Flexible, Robust and Efficient physical Human-robot Interaction with iterative learning and self-triggered role adaption |
| Amount | £331,094 (GBP) |
| Funding ID | EP/V057782/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2022 |
| End | 01/2025 |
| Description | Grow MedTech POF grant - Evaluation of HyFaCol-PDT prototype (Tronci POC 78) |
| Amount | £10,000 (GBP) |
| Organisation | Grow MedTech |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 02/2019 |
| End | 08/2019 |
| Description | Grow MedTech Project Proof of Concept Award - SNIPER-X |
| Amount | £80,000 (GBP) |
| Organisation | Grow MedTech |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2019 |
| End | 09/2020 |
| Description | Grow MedTech Proof of Feasibility Award (Southgate POC 045) |
| Amount | £20,000 (GBP) |
| Organisation | Grow MedTech |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2018 |
| End | 03/2019 |
| Description | IKC POC055 KTP with 3D Metal Printing Ltd |
| Amount | £140,000 (GBP) |
| Organisation | Knowledge Transfer Partnerships |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2021 |
| End | 12/2023 |
| Description | IKC POC055 TOKA FE Modeller - Innovate UK funding with 3D Metal Printing Ltd |
| Amount | £100,000 (GBP) |
| Organisation | Innovate UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2020 |
| End | 09/2021 |
| Description | IKC POC064 - Confidence-in-Concept Grant |
| Amount | £85,834 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2023 |
| End | 06/2024 |
| Description | IKC POC078 - Regulatory compliance of HyFaCol with ISO 22442 standards - (medical devices utilising animal tissues and their derivatives) |
| Amount | £10,000 (GBP) |
| Organisation | University of Leeds |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | |
| Description | IKC POC078 Biodegradable fibres of bacteria-generated bioplastics for antimicrobial face masks. LITAC PhD scholarship |
| Amount | £90,000 (GBP) |
| Organisation | University of Leeds |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | |
| Description | IKC POC081 - EPSRC-IAA |
| Amount | £35,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2021 |
| End | 03/2022 |
| Description | IKC POC084 Norman Collisson Foundation grant |
| Amount | £280,000 (GBP) |
| Organisation | Norman Collisson Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | ImagingBioPro Network: Proof of Concept Award (PoCA) - Hierarchical morphometric analysis of normal and degenerate intervertebral disc under physiological load. |
| Amount | £16,115 (GBP) |
| Organisation | United Kingdom Research and Innovation |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2020 |
| End | 07/2020 |
| Description | Industry Biocomposites |
| Amount | £150,000 (GBP) |
| Organisation | Biocomposites |
| Sector | Private |
| Country | United Kingdom |
| Start | 07/2015 |
| End | 07/2016 |
| Description | Industry Invibio |
| Amount | £300,000 (GBP) |
| Organisation | Invibio |
| Sector | Private |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 10/2017 |
| Description | Key partner in the consortia, consortia lead by M Tryfonidou Utercht University Netherlands. H2020 iPSpine. 15,396,030 Euro (1,126,573 Euro for SHU).(~£13,600,000) (POC057 Sammon Le Maitre SHU) |
| Amount | € 15,396,030 (EUR) |
| Funding ID | H2020 iPSpine |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 01/2019 |
| End | 12/2024 |
| Description | MRC Proximity to Discovery |
| Amount | £34,762 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2018 |
| End | 07/2019 |
| Description | Medcial engineering centre |
| Amount | £160,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2015 |
| End | 07/2019 |
| Description | Medical Technologies IKC / Versus Arthritis Proof of Concept Call |
| Amount | £99,995 (GBP) |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2021 |
| End | 04/2022 |
| Description | Omental derived stem cells to prevent anastomotic leak |
| Amount | £60,000 (GBP) |
| Organisation | Royal College of Surgeons of England |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2021 |
| End | 06/2022 |
| Description | PASHiOn: Personalised Against Standard High tibial Osteotomy, a prospective multi-centre randomised controlled trial study |
| Amount | £780,210 (GBP) |
| Funding ID | 22262 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 06/2023 |
| Description | POC 60 (Miller) - collaborative lap placement |
| Amount | £500 (GBP) |
| Organisation | United Kingdom Society for Biomaterials |
| Sector | Charity/Non Profit |
| Start | 07/2019 |
| End | 07/2019 |
| Description | POC 60 (Miller) continuation of Ceramisys funding |
| Amount | £44,823 (GBP) |
| Organisation | Ceramisys |
| Sector | Private |
| Country | United Kingdom |
| Start | 09/2019 |
| End | 11/2021 |
| Description | POC 69 (Herrick) - Kidneys for Life |
| Amount | £8,626 (GBP) |
| Organisation | Kidneys for Life |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2019 |
| End | 06/2020 |
| Description | Proof of Feasibility - EPSRC - University of Leeds IAA |
| Amount | £74,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | RCS Eng. Clinical Research Fellowship - Josh Burke |
| Amount | £60,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Restore healthy biomechanics after early intervention orthopaedic surgery |
| Amount | £1,999,618 (GBP) |
| Funding ID | NIHR300013 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2019 |
| End | 10/2024 |
| Description | Royal Society Research Grant |
| Amount | £14,894 (GBP) |
| Organisation | The Royal Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | SNIPER X follow on funding |
| Amount | £9,000 (GBP) |
| Organisation | Grow MedTech |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 12/2020 |
| End | 05/2021 |
| Description | Smart Bone Regeneration |
| Amount | € 6,200,000 (EUR) |
| Funding ID | H2020-SC1-2019-874896 |
| Organisation | European Commission H2020 |
| Sector | Public |
| Country | Belgium |
| Start | 01/2020 |
| End | 01/2023 |
| Description | Smart, Multifunctional Dental Implants: A Solution for Peri-Implantitis and Bone Loss |
| Amount | € 5,100,000 (EUR) |
| Funding ID | H2020-NMBP-TR-IND-2020-953128 |
| Organisation | European Commission H2020 |
| Sector | Public |
| Country | Belgium |
| Start | 04/2021 |
| End | 03/2025 |
| Description | The Future Vaccine Manufacturing Research Hub (Vax-Hub) |
| Amount | £191,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2019 |
| End | 01/2021 |
| Description | Wellcome Trust Translation Accelerator award (Jeffers POC-61) |
| Amount | £1,000,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2019 |
| End | 06/2020 |
| Description | White Rose Mucosal Drug Delivery Network |
| Amount | £10,000 (GBP) |
| Organisation | White Rose University Consortium |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | |
| Description | depuy |
| Amount | £250,000 (GBP) |
| Organisation | Depuy International |
| Sector | Private |
| Country | United Kingdom |
| Start | 01/2017 |
| End | 01/2018 |
| Description | epsrc |
| Amount | £1,000,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2015 |
| End | 07/2020 |
| Description | invibio |
| Amount | £200,000 (GBP) |
| Organisation | Invibio |
| Sector | Private |
| Country | United Kingdom |
| Start | 12/2016 |
| End | 12/2018 |
| Description | lmbrc |
| Amount | £7,500,000 (GBP) |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 04/2022 |
| Title | Ankle joint simulation |
| Description | Ankle joint simulation system |
| Type Of Material | Model of mechanisms or symptoms - human |
| Provided To Others? | No |
| Impact | Wear prediction in total ankle joint |
| Title | Biochemical degradation model (McCarthy POC068) |
| Description | Biochemical degradation model representing in vivo degradation process in mice aiming to reduce number of animals used during degradation studies. |
| Type Of Material | Model of mechanisms or symptoms - mammalian in vivo |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | Biochemical degradation model representing in vivo degradation process in mice aiming to reduce number of animals used during degradation studies. |
| Title | Goat degeneration loading model |
| Description | Loaded culture system for whole intervertebral discs where controlled degeneration can be induced which mimics disc degeneration seen in humans. (note publication under review) |
| Type Of Material | Model of mechanisms or symptoms - in vitro |
| Year Produced | 2019 |
| Provided To Others? | No |
| Impact | This model can be used for testing new therapies. |
| Title | ISO standard for wear testing of total ankle replacement |
| Description | Contribution to an international standard for the assessment of wear performance in total ankle devices. |
| Type Of Material | Model of mechanisms or symptoms - human |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | New standard to which all future ankle replacement designs must be tested prior to clinical study. |
| URL | http://www.iso.org/standard/73612.html |
| Title | Knee joint simulator |
| Description | artificial knee joint simulator |
| Type Of Material | Model of mechanisms or symptoms - in vitro |
| Year Produced | 2013 |
| Provided To Others? | Yes |
| Impact | Simulator and simulation method commercialised by simulation solution |
| Title | Method to assess early phase of cartilage degeneration (POC041 J Dudhia) |
| Description | RAMAN spectroscopy method t assess early cartilage damage and degradation for use in Clinical practise or research |
| Type Of Material | Physiological assessment or outcome measure |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | none yet - still in development |
| Title | MicroTissue in vitro model |
| Description | Cell pelletes were used incombination with 3D printed scaffold for MicroTissue in vitro model to enhance tissue engineering efficacy. |
| Type Of Material | Physiological assessment or outcome measure |
| Provided To Others? | No |
| Impact | This method could help to establish new in vitro model for replacement of animal used and help for investigate tissue engineering stratagy in 3D. |
| Title | Natural knee simulator |
| Description | Simulation system for natural knee |
| Type Of Material | Model of mechanisms or symptoms - in vitro |
| Year Produced | 2013 |
| Provided To Others? | Yes |
| Impact | Simulator commercially available, Simulation Solutions |
| Title | New Freeze Drier for development of Chitosan Scaffolds |
| Description | New Freeze Drier acquired to enable development of Chitosan Scaffolds for periodontal regeneration |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | The equipment enabled the research to be conducted |
| Title | Patellar simulation |
| Description | Simulation of mechanics and wear of patellae femoral joint |
| Type Of Material | Model of mechanisms or symptoms - human |
| Year Produced | 2015 |
| Provided To Others? | Yes |
| Impact | Determination of wear in patellar femoral joint |
| Title | Simulation of bone healing within the ostotomy gap (BJR publication) |
| Description | Simulation of bone healing within the ostotomy gap (BJR publication) |
| Type Of Material | Model of mechanisms or symptoms - human |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | Improved method |
| URL | https://www.ncbi.nlm.nih.gov/pubmed/30662711 |
| Title | development of a novel bioreactor for peridontal tissue engineering |
| Description | A novel in vivo bioractor has been developed to apply mechanical simulation to the cell-scaffold constructs to mimic peridontal enviroment to enhance the regeneration of periodontal tissues. |
| Type Of Material | Physiological assessment or outcome measure |
| Provided To Others? | No |
| Impact | To enhance the efficacy of peridontal tissue regenration which will have impact for clinical translation. |
| Title | natural hip simulator |
| Description | Simulation system for natural hip |
| Type Of Material | Model of mechanisms or symptoms - mammalian in vivo |
| Year Produced | 2014 |
| Provided To Others? | Yes |
| Impact | System commercially availa le from Simulation Solutions |
| Title | Biological, mechanical and structural data associated with the decellularisation of human bone tibial plateau and femoral head trabecular bone |
| Description | Supplementary data associated with the research paper: Decellularised human bone allograft from different anatomical sites as a basis for functionally stratified repair material for bone defects. Dataset comprised of histological images, DNA assay, biomechanical and structural data for human trabecular bone from the tibial plateau and femoral head. Data provided for cellular and decellularised samples. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2021 |
| Provided To Others? | Yes |
| Impact | All Micro-CT data describing the structural propeties of femoral and tibial bone groups, prior to and post decellularisation are available openaccess on the University of Leeds data repositiory. Also inculded are the mechanical properties of the bone groups prior to and post decellularisation. This id the first time data such as this has been made available publically and will act as a valuable resource to others for comparison |
| URL | https://archive.researchdata.leeds.ac.uk/902/ |
| Title | Biomechanical and biotribological simulation model natural hip |
| Description | Biomechanical and biotribological model of natural hip |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2013 |
| Provided To Others? | Yes |
| Impact | used in follow on research |
| Title | Biomechanical model of functional spinal unit |
| Description | model of functional spinal unit |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2014 |
| Provided To Others? | Yes |
| Impact | used in follow on research |
| Title | Biotribological model naturala knee |
| Description | Biotribological model natural knee |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2014 |
| Provided To Others? | Yes |
| Impact | Used in follow on research on regenerative devices |
| Title | Characteristics of low concentration SDS decellularised human donor aortic and pulmonary valved conduits. |
| Description | Data on the biological and biomechanical properties of human donor aortic and pulmonary cardiac valves before and after decellularisation: biomechanical testing data (ultimate tensile strength, failure strain, Young's modulus); DNA, collagen and GAG content; in vitro biocompatibility. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Impact | Pre-clinical data that reduces need for in vivo animal studies |
| URL | http://archive.researchdata.leeds.ac.uk/35/ |
| Title | Combined Wear and Ageing of Ceramic-on-Ceramic Bearings in Total Hip Replacement under Edge Loading Conditions |
| Description | Data associated with the paper "Combined Wear and Ageing of Ceramic-on-Ceramic Bearings in Total Hip Replacement under Edge Loading Conditions" |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/526/ |
| Title | Data Associated with "The effect of surgical alignment and soft tissue conditions on the kinematics and wear of a fixed bearing total knee replacement" |
| Description | Data associated with the paper "The effect of surgical alignment and soft tissue conditions on the kinematics and wear of a fixed bearing total knee replacement". This dataset contains: - Figure 3. The raw data for mean output AP displacement with the 95% CI for each alignment condition under the stiff knee, preserved PCL and resected PCL soft tissue conditions. - Figure 4. The raw data for mean output TR rotation with the 95% CI for each alignment condition under the stiff knee, preserved PCL and resected PCL soft tissue conditions. - Figure 5. The raw data for mean output AA rotation with the 95% CI for each alignment condition under the stiff knee, the preserved PCL and the resected PCL soft tissue conditions. - Figure 6. The raw data for Mean wear rates with 95% CI over 2 MC for the ideal, 4° varus, 14° rotational mismatch and 10° tibial slope alignment conditions for two soft tissue conditions. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/661/ |
| Title | Data associated with "An experimental simulation model to assess wear of the porcine patellofemoral joint" |
| Description | The dataset contains material to supplement the paper "An experimental simulation model to assess wear of the porcine patellofemoral joint" including: ICRS cartilage score of the patella and femur after 3 hours wear simulation, the wear volume, deformation and damage of the cartilage on the femoral trochlear after 3 hours wear simulation, the protrusion of the pin/osteochondral graft from the cartilage surface pre- and post-test and height maps showing the position of the osteochondral grafts pre- and post-test taken from Accutrans replicas of the cartilage surfaces. The aim of this study was to develop an experimental simulation model to pre-clinically assess and predict the wear of osteochonal allografts in the natural porcine patellofemoral joint |
| Type Of Material | Database/Collection of data |
| Year Produced | 2021 |
| Provided To Others? | Yes |
| Impact | Dataset has enabled reuse of material for further research and training. |
| URL | http://archive.researchdata.leeds.ac.uk/830/ |
| Title | Data associated with "Biomechanical assessment of the stability of osteochondral grafts implanted in porcine and bovine femoral condyles" |
| Description | The dataset contains material to supplement the paper "Biomechanical assessment of the stability of osteochondral grafts implanted in porcine and bovine femoral condyles" including push in force measurements and maximum push out forces relating to figures 4, 5, 7 & 8 in the manuscript. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | Pre-clinical data that reduces need for in vivo animal studies |
| URL | http://archive.researchdata.leeds.ac.uk/604/ |
| Title | Data associated with "PEEK-OPTIMA (Trademark) as an Alternative to Cobalt Chrome in the Femoral Component of Total Knee Replacement: A Preliminary Study". |
| Description | The dataset contains material to supplement the paper "PEEK-OPTIMA (Trademark) as an Alternative to Cobalt Chrome in the Femoral Component of Total Knee Replacement: A Preliminary Study" including: wear rates of UHMWPE tibial components articulating against PEEK-OPTIMA (Trademark) and cobalt chrome femoral components under two kinematic conditions, surface roughness analysis of PEEK-OPTIMA and cobalt chrome femoral components following wear simulation using a contacting Form Talysurf and measurements of the bulk lubricant temperature using a thermocouple. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/74/ |
| Title | Data associated with "The Influence of Malalignment and Ageing Following Sterilisation by Gamma Irradiation in an Inert Atmosphere on the Wear of UHMWPE in Patella-Femoral Replacements". |
| Description | The dataset contains material to supplement the paper "The Influence of Malalignment and Ageing Following Sterilisation by Gamma Irradiation in an Inert Atmosphere on the Wear of UHMWPE in Patella-Femoral Replacements" including: wear rates of UHMWPE patellae, surface roughness of patellae using the contacting Form Talysurf and analysis of the size of the wear scars. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/111/ |
| Title | Data associated with "Third body wear of UHMWPE-on-PEEK-OPTIMA™" |
| Description | The dataset contains material to supplement the paper "Third body wear of UHMWPE-on-PEEK-OPTIMA™" including: measurements of the surface topography of PEEK and cobalt chrome plates following third body damage simulation with particles of PMMA cement and wear factors of UHMWPE against PEEK and cobalt chrome plates damaged both with cement particles and scratched with a diamond stylus. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| Impact | Pre-clinical data that reduces need for in vivo animal models |
| URL | http://archive.researchdata.leeds.ac.uk/658/ |
| Title | Data associated with "Wear and Friction of UHMWPE-on-PEEK OPTIMA™" |
| Description | The dataset contains material to supplement the paper "Wear and Friction of UHMWPE-on-PEEK OPTIMA™" by Cowie R M., Briscoe A, Fisher J, Jennings LM (2019) J. Mech. Behav. Biomed. Mater. Volume 89, January 2019, Pages 65-71. https://doi.org/10.1016/j.jmbbm.2018.09.021 |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/423/ |
| Title | Data associated with 'Development of a pre-clinical experimental simulation model of the natural porcine knee with appropriate ligamentous constraints' |
| Description | The dataset will include all the data for figures in the manuscripts as shown in the followings: Fig 2. Porcine kinematic input profiles. Fig 5.Typical kinematic output profiles of A/P displacement and A/P shear force from the intact knee (all ligaments retained) and different spring free length conditions. Fig 6. Comparison of differences of A/P displacement and A/P shear force under different free length conditions. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | Pre-clinical data that reduces need for in vivo animal studies |
| URL | http://archive.researchdata.leeds.ac.uk/515/ |
| Title | Data associated with 'Development of a specimen-specific in vitro pre-clinical simulation model of the human cadaveric knee with appropriate soft tissue constraints' |
| Description | The dataset will include all the data. for figures in the manuscripts as shown in the followings: 1) Kinematic input profiles for the human cadaveric knee. 2) Average AP displacement and TR angle of the 4 human knee specimens in a human walking gait cycle (both AP and TR force driven condition). 3) Typical kinematic profiles from one donor under different spring conditions for different spring rates and free lengths/degrees 4) Comparison of kinematic profiles (AP displacement and TR angle) of the intact knee and the most appropriate spring constraints from four human knee specimens. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| Impact | Pre-clinical data that reduces need for in vivo animal studies |
| URL | http://archive.researchdata.leeds.ac.uk/736/ |
| Title | Data associated with 'In vitro biomechanical and hydrodynamic characterisation of decellularised human pulmonary and aortic roots' |
| Description | This study has performed full and robust assessment of biomechanical and hydrodynamic properties of decellularised cryopreserved human aortic and pulmonary roots. Findings from this study will serve as a step forward to use decellularised human heart valves for clinical trial. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | Pre-clinical data that reduces need for in vivo animal studies |
| URL | http://archive.researchdata.leeds.ac.uk/304/ |
| Title | Data associated with 'The Influence of Calcium Sulfate Bone Void Filler on the Third Body Damage and Polyethylene Wear of Total Knee Replacements' |
| Description | The dataset contains material to supplement the paper "The Influence of Calcium Sulfate Bone Void Filler on the Third Body Damage and Polyethylene Wear of Total Knee Replacements" including: wear rates and wear volumes of UHMWPE tibial components and surface roughness analysis of cobalt chrome femoral components following both third body damage simulation and experimental wear simulation using a contacting Form Talysurf. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/436/ |
| Title | Data associated with 'The Influence of Kinematic Conditions and Variations in Component Positioning on the Severity of Edge Loading andWear of Ceramic-on-Ceramic Hip Bearings' |
| Description | Data associated with the paper "The Influence of Kinematic Conditions and Variations in Component Positioning on the Severity of Edge Loading and Wear of Ceramic-on-Ceramic Hip Bearings". This dataset contains: - Figure 4. Dynamic separation (mean +/- 95% confidence limits, n = 3) of 36 mm diameter BIOLOX®delta ceramic-on-ceramic bearings under two axes and three axes of rotation conditions with 45 degree and 65 degree cup inclination angle conditions and 1, 2, 3 and 4 mm of medial-lateral translational mismatch conditions. - Figure 5. Load at the rim at separation (mean +/- 95% confidence limits, n = 3)of 36 mm diameter BIOLOX®delta ceramic-on-ceramic bearings under two axes and three axes of rotation conditions at 45 degree and 65 degree cup inclination angles with 1, 2, 3 and 4 mm of medial-lateral translational mismatch. - Figure 6. Severity of edge loading (mean ± 95% confidence limits, n = 3) of 36 mm diameter BIOLOX®delta ceramic-on-ceramic bearings under two axes and three axes of rotation conditions with 45 degree and 65 degree cup inclination angles and 1, 2, 3 and 4 mm of medial-lateral translational mismatch conditions (offset deficiency). - Figure 7. Wear rates (mean ± 95% confidence limits, n = 6) of 36 mm diameter BIOLOX®delta ceramicon-ceramic bearings under two axes and three axes of rotation conditions with 45 degree and 65 degree cup inclination angles and 4 mm of medial-lateral translational mismatch conditions. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/665/ |
| Title | Data set for paper "Representing the Effect of Variation in Soft Tissue Constraints in Experimental Simulation of Total Knee Replacements" |
| Description | Data set for paper "Representing the effect of variation in soft tissue constraints in experimental simulation of total knee replacements". Data includes experimental results from a knee simulator that are represented in the figures and text of the paper. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/id/eprint/400 |
| Title | Dataset associated with 'Development of a preclinical natural porcine knee simulation model for the tribological assessment of osteochondral grafts in vitro'. University of Leeds. |
| Description | Data associated with the paper "Development of a preclinical natural porcine knee simulation model for the tribological assessment of osteochondral grafts in vitro". This dataset contains: - Figure 4. Mean shear force values at 120 min test duration plotted against time during one cycle (1s) of the gait cycle (n = 4). - Figure 5. Mean displacement values at 120 min test duration plotted against time during one cycle (1s) of the gait cycle (n = 4). - Figure 7. Volume (mm3) extending beneath the meniscal surface - Figure 8. Penetration depth measured in areas of damage, wear and deformation on the meniscal surface |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Pre-clinical data that reduces need for in vivo animal studies |
| URL | http://archive.researchdata.leeds.ac.uk/id/eprint/454 |
| Title | Dataset supporting the publication "Importance of dynamics in the finite element prediction of plastic damage of polyethylene acetabular liners under edge loading conditions" |
| Description | This dataset contains the full set of output values from a modelling study, summarised as follows. After hip replacement, in cases where there is instability at the joint, contact between the femoral head and the acetabular liner can move from the bearing surface to the liner rim, generating edge loading conditions. This has been linked to polyethylene liner fracture and led to the development of a regulatory testing standard (ISO 14242:4) to replicate these conditions. Performing computational modelling alongside simulator testing can provide insight into the complex damage mechanisms present in hard-on-soft bearings under edge loading. The aim of this work was to evaluate the need for inertia and elastoplastic material properties to predict kinematics (likelihood of edge loading) and plastic strain accumulation (as a damage indicator). While a static, rigid model was sufficient to predict kinematics for experimental test planning, the inclusion of inertia, alongside elastoplastic material, was required for prediction of plastic strain behaviour. The delay in device realignment during heel strike, caused by inertia, substantially increased the force experienced during rim loading (e.g. 600 N static rigid, ~1800 N dynamic elastoplastic, in one case). The accumulation of plastic strain is influenced by factors including cup orientation, swing phase force balance, the moving mass, and the design of the device itself. Evaluation of future liner designs could employ dynamic elastoplastic models to investigate the effect of design feature changes on bearing resilience under edge loading. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2021 |
| Provided To Others? | Yes |
| Impact | Dataset has enabled reuse of material for further research and training. |
| URL | http://archive.researchdata.leeds.ac.uk/840/ |
| Title | Dataset supporting the publication 'A Comprehensive Combined Experimental and Computational Framework for Pre-clinical Wear Simulation of Total Knee Replacements' |
| Description | A more robust pre-clinical wear simulation framework is required in order to simulate wider and higher ranges of activities, observed in different patient populations such as younger more active patients. Such a framework will help to understand and address the reported higher failure rates for younger and more active patients (National_Joint_Registry, 2016). The current study has developed and validated a comprehensive combined experimental and computational framework for pre-clinical wear simulation of total knee replacements (TKR). The input mechanical (elastic modulus and Poisson's ratio) and wear parameters and of the moderately cross-linked ultra-high molecular weight polyethylene (UHMWPE) bearing material were independently measured from experimental studies under realistic test conditions, similar to the loading conditions found in the total knee replacements.. The wear predictions from the computational wear simulation were validated against the direct experimental wear measurements for size 3 Sigma curved total knee replacements (DePuy, UK) in an independent experimental wear simulation study under three different daily activities; walking, deep squat, and stairs ascending kinematic conditions. The measured compressive mechanical properties of the moderately cross-linked UHMWPE material were more than 20% lower than that reported in the literature under tensile test conditions. The pin-on-plate wear coefficient of moderately cross-linked UHMWPE was significantly dependant of the contact stress and the degree of cross-shear at the articulating surfaces. The computational wear predictions for the TKR from the current framework were consistent and in a good agreement with the independent full TKR experimental wear simulation measurements, with 0.94 coefficient of determination of the framework. In addition, the comprehensive combined experimental and computational framework was able to explain the complex experimental wear trends from the three different daily activities investigated. Therefore, such a framework can be adopted as a pre-clinical simulation approach to optimise different designs, materials, as well as patient's specific total knee replacements for a range of activities. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/301/ |
| Title | Dataset supporting the publication 'A comparison between electromechanical and pneumatic controlled knee simulators for the investigation of wear of total knee replacements' |
| Description | More robust pre-clinical experimental wear simulation methods are required in order to simulate a wider range of activities, observed in different patient populations such as younger more active patients, as well as fully meeting and being capable of going well beyond the existing requirements of the relevant international standards. A new six station electromechanically driven simulator (Simulation Solutions, UK) with five fully independently controlled axes of articulation for each station, capable of replicating deep knee bending as well as other adverse conditions, which can be operated in either force or displacement control with improved input kinematic following, has been developed to meet these requirements. This study investigated the wear of a fixed bearing total knee replacement using this electromechanically driven fully independent knee simulator, and compared it to previous data from a predominantly pneumatically controlled simulator in which each station was not fully independently controlled. In addition, the kinematic performance and the repeatability of the simulators have been investigated and compared to the international standard requirements. The wear rates from the electromechanical and pneumatic knee simulators were not significantly different, with wear rates of 2.6 ± 0.9 and 2.7 ± 0.9 [mm3/MC] (mean ± 95% CI, p=0.99) and 5.4 ± 1.4 and 6.7 ± 1.5 [mm3/MC] (mean ± 95% CI, p=0.54) from the electromechanical and pneumatic simulators, under intermediate levels (maximum 5 mm) and high levels (maximum 10 mm) of AP displacements respectively. However, the output kinematic profiles of the control system, which drives the motion of the simulator followed the input kinematic profiles more closely on the electromechanical simulator than the pneumatic simulator. In addition, the electromechanical simulator was capable of following kinematic and loading input cycles within the tolerances of the international standard requirements (ISO 14243-3, 2014). The new generation electromechanical knee simulator with fully independent control has the potential to be used for a much wider range of kinematic conditions, including high-flexion and other severe conditions, due to its improved capability and performance in comparison to the previously used pneumatic controlled simulators. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/131/ |
| Title | Dataset supporting the publication 'Dynamic finite element analysis of hip replacement edge loading: balancing precision and run time in a challenging model' |
| Description | This dataset contains the full set of output values from a modelling study, summarised as follows. An important aspect in evaluating the resilience of hip replacement designs is testing their performance under adverse conditions that cause edge loading of the acetabular liner. The representation of edge loading conditions in computational models is computationally challenging, however, due to the changing contact locations, need for mesh refinement, and dynamic nature of the system. In the associated paper, an initial starting point for finite element modelling of this type of testing was developed. This consisted of recommendations for aspects such as the element type and shape, and to set up the head as the translating component and fix the liner using boundary conditions. It also included recommendations for element sizing for the bulk of the liner and the contacted rim, and a mass-scaling target time increment for the elements of the liner. In the paper we present a relatively clean sensitivity study to justify these choices and describe the sensitivity of results around them so that someone putting together a new model can hopefully do so far more quickly. There was a large amount of underpinning sensitivity testing, however, which was less structured but important for getting to this final recommendation. This data packet therefore contains results from two preliminary load cases (A and B) as well as the data used in the supported paper (case C). |
| Type Of Material | Database/Collection of data |
| Year Produced | 2023 |
| Provided To Others? | Yes |
| Impact | Dataset has enabled reuse of material for further research and training. |
| URL | https://archive.researchdata.leeds.ac.uk/1065/ |
| Title | Development and Evaluation of a Functional Prototype for the Automated Identification of Osteoporotic Vertebral Fractures: VERDICT |
| Description | The VFA (anteroposterior and lateral) anonymised images of 500 patients (250 with vertebral fractures and 250 without vertebral fractures) previously assessed within the fracture Risk assessment (FRAS) pathway at MBC, Sheffield. • A spreadsheet including patient diagnosis (i.e. vertebral fracture or no vertebral fracture from the clinician reports stored on STH's Picture and Archiving Communication System (PACS)) , age, gender, height and weight data (i.e. population characteristics). • A spreadsheet containing visual readings of the 500 patient images (mentioned above) by an expert reader. Data are recorded on both (i) a patient-by-patient basis and (ii) a vertebra-by-vertebra basis. The grade and type of fracture are recorded in this spreadsheet. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | No |
| Impact | Key outcomes of this project, the POC prototype and the ground truth dataset, have enabled us to formulate further collaborations and jointly prepare proposals with multiple stakeholders. Our short-term objective is to complete the clinical assessment, gathering more clinical evidence of the usability and efficacy of the VERDICT, and improve the software robustness and efficiency |
| Title | Drug loading capacity of microporous ß-pyrophosphate crystals - dataset |
| Description | Periodontitis and peri-implantitis are two characteristic examples where bacterial infections compromise the healing of dental tissues. Drug eluting scaffolds are a potential solution to this problem but their fabrication requires suitable biomaterials with significant drug loading capacity and regenerative potential to support new tissue formation. With this aim, porous ß-pyrophosphate crystals having a micro-pore area of 2.59 m2/g and an average pore diameter of 65 nm, have been obtained by the heat treatment of brushite (at 780 oC). To demonstrate the drug loading potential of the mineral, experiments with chloramphenicol have been conducted. After tests with four common bacteria, the drug loaded mineral was shown to have enhanced antibacterial properties, particularly towards E. coli (74% growth inhibition) and S. aureus (48% growth inhibition). Taking into account ß-pyrophosphate's significant role in hard tissue mineralisation and the capability to tailor crystal micro-porosity characteristics by controlled heat treatment, the mineral can be considered as an ideal biomaterial for localised drug delivery in dental applications. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| Title | Hydrodynamic mixing tunes the stiffness of proteoglycan-mimicking physical hydrogels |
| Description | Supplementary data associated with research paper: Hydrodynamic mixing tunes the stiffness of proteoglycan-mimicking physical hydrogels. Dataset comprised of rheological data for peptide: glycosaminoglycan (GAG) hydrogels; FT-IR data for peptide: GAG hydrogels dimensional analysis data for peptide: GAG hydrogels. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2021 |
| Provided To Others? | Yes |
| Impact | Dataset has enabled reuse of material for further research and training. |
| URL | https://archive.researchdata.leeds.ac.uk/880/ |
| Title | IKC POC0053 - VFA (Vertebral Fracture Analysis) |
| Description | Synthetic shape model of the vertebral fracture modes merged with the statistical shape model of the spine. Method for the sampling of synthetic spines with fracture. Method for the projection of the 3D model into a VFA-like 2D projection. This will be used to further train the fracture assessment algorithm for improving its accuracy. |
| Type Of Material | Computer model/algorithm |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Improved main algorithm speed. Developed automatic landmark location - implementing a method which should allow to automatically locate the intervertebral disc centres from one or two manually identified centres. The method is based on statistical models of shape and appearance. A first version requiring the manual identification of two vertebrae is implemented. An advanced version requiring only one manual vertebra identification is being explored. |
| Title | Influence of conformity on the wear of total knee replacement: An experimental study - dataset. University of Leeds. |
| Description | Wear of total knee replacement continues to be a significant factor influencing the clinical longevity of implants. The aim of this study was to investigate the effect of insert conformity on the wear performance of a fixed bearing total knee replacement through experimental simulation. Two geometries of insert were studied under standard gait conditions. This dataset contains the images and wear data relating to the study understanding conformity influence on wear of a fixed bearing total knee replacement. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/id/eprint/422 |
| Title | Native, GAG depleted and decellularised porcine tendon under tension and compression data set |
| Description | This dataset containes experimental mechanical and biochemical data as described in https://doi.org/10.1016/j.jmbbm.2023.105671. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2023 |
| Provided To Others? | Yes |
| Impact | Dataset has enabled reuse of material for further research and training. |
| URL | https://archive.researchdata.leeds.ac.uk/1062/ |
| Title | PEEK CFR-PEEK pin plate study dataset |
| Description | Pin on plate studies to understand the influence of contact pressure, cross shear and counterface were undertaken with surface analysis measured prior to test and at completion. Mean wear factors for each condition were calculated at the completion of the study. This dataset includes the mean wear factor for each condition and the surface roughness measurements. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/92/ |
| Title | PEEK and CFR-PEEK knee wear dataset |
| Description | This study investigated the wear performance of PEEK and CFR-PEEK in a low conformity total knee replacement configuration. Custom-made flat inserts were tested against cobalt-chromium femoral bearings in a knee wear simulation for a period of three million cycles. Wear was assessed gravimetrically at intervals throughout the study. This dataset presents the input profile for the knee wear simulator, the experimental wear data and associated figures relating to the paper |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/137/ |
| Title | Simple Geometry Tribological Study of Osteochondral Graft Implantation in the Knee dataset |
| Description | The dataset contains material to supplement the paper "Simple Geometry Tribological Study of Osteochondral Graft Implantation in the Knee" including: coefficient of dynamic friction (and change in); volume and depth of articular cartilage surface damage/wear/deformation. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | None |
| URL | http://archive.researchdata.leeds.ac.uk/302/ |
| Title | Stability of Osteochondral Grafts within Porcine Femoral Condyles - experimental, imaging and computational data for preclinical assessment |
| Description | The dataset contains the raw microCT scan data, computational and experimental test results, and scripts used in the associated paper. Specifically, this is testing data for the bone material property derivation of porcine femoral condyles and stability testing of porcine osteochondral allografts. Example finite element example models are also included, provided in INP format. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2022 |
| Provided To Others? | Yes |
| Impact | Dataset has enabled reuse of material for further research and training. |
| URL | https://archive.researchdata.leeds.ac.uk/1058/ |
| Title | The effect of decellularisation on the real time mechanical fatigue of porcine aortic heart valve roots |
| Description | In Vitro data related to real time fatigue, hydrodynamic function and mechanical properties of cellular and low concentration sodium dodecyl sulphate decellularised porcine aortic heart heart valve roots |
| Type Of Material | Database/Collection of data |
| Year Produced | 2022 |
| Provided To Others? | Yes |
| Impact | Dataset has enabled reuse of material for further research and training. |
| URL | https://archive.researchdata.leeds.ac.uk/939/ |
| Title | VFA (Vertebral Fracture Analysis) Image repository - XNAT |
| Description | Database repository implementation to be completed by Nov 2018 - ongoing |
| Type Of Material | Database/Collection of data |
| Year Produced | 2018 |
| Provided To Others? | Yes |
| Impact | Dec 18 - All fracture and non-fracture cases have been identified.(500). All VFA and DXA images have been retrieved, anonymised and uploaded to the XNAT server. |
| Description | |
| Type Of Material | Database/Collection of data |
| Year Produced | 2019 |
| Provided To Others? | Yes |
| URL | http://archive.researchdata.leeds.ac.uk/627/ |
| Description | Amsterdam |
| Organisation | VU University Medical Center |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Knowledge on intervertebral disc degeneration and pathogenesis. Novel therapies for new treatments |
| Collaborator Contribution | Loading environment and culture systems for modelling intervertebral disc |
| Impact | none yet |
| Start Year | 2017 |
| Description | Ceramisys Ltd (POC049 - Miller) |
| Organisation | Ceramisys |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | The research are working to validate a new range of bone filler material. |
| Collaborator Contribution | The partner provide industrial processed material for testing. The partner brings regulatory, manufacturing and marketing knowledge regarding this med tech sector. |
| Impact | The project brings research experience from engineering, dentistry and microbiology. |
| Start Year | 2016 |
| Description | Collaboration with Credentis to support commercialisation of self assembling peptide P11-4 |
| Organisation | Credentis |
| Country | Switzerland |
| Sector | Private |
| PI Contribution | Provided data to support regulatory approval of product in USA |
| Collaborator Contribution | Credentis provide expertise, technical support and supply test materials (SAPs) |
| Impact | Multidisciplinary collaboration bringing together bioogy, chemistry, business, dental and oral biology. |
| Description | Collaboration with David Russell within an MD supervision project |
| Organisation | Leeds Teaching Hospitals NHS Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Student: SR, Leeds General Infirmary |
| Collaborator Contribution | Student: SR, Leeds General Infirmary |
| Impact | None known |
| Start Year | 2019 |
| Description | Corin |
| Organisation | Corin Group PLC |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | research |
| Collaborator Contribution | funds time materials |
| Impact | multidisciplinary engineering medicine |
| Start Year | 2016 |
| Description | Cytori Ltd (POC046 - Jayne) |
| Organisation | Cytori Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | The research team have provided additional validation of the company's cell separation system against a manual system and for an alternative tissue type. |
| Collaborator Contribution | The partner have provided free of cost use of cell separation system and reduced reagent cost. |
| Impact | The collaboration involved researchers from chemical & process engineering, biomedical sciences and colorectal surgery. |
| Start Year | 2016 |
| Description | DePuy partnership 2016 |
| Organisation | Depuy International |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Research supply |
| Collaborator Contribution | Research funding cash, materials and in kind |
| Impact | publications IP multidisciplinary, engineering medicine biology |
| Start Year | 2016 |
| Description | DePuy partnership 2017 |
| Organisation | Depuy International |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Research supply |
| Collaborator Contribution | Funding, materials , know how, staff time |
| Impact | publications multidisciplinary engineering biological sciences, medicine |
| Start Year | 2017 |
| Description | Depuy Kennedy 16-17 |
| Organisation | Depuy International |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Knowledge advice |
| Collaborator Contribution | knowledge expertise |
| Impact | multidiciplines engineering medicine |
| Start Year | 2016 |
| Description | Depuy Nutter 16-17 |
| Organisation | DePuy Synthes |
| Country | United States |
| Sector | Private |
| PI Contribution | Research , knowledge advice |
| Collaborator Contribution | advice , knowledge |
| Impact | knowledge advice multidisciplinary engineering biology medicine |
| Start Year | 2016 |
| Description | Edwards Powell 2016-17 |
| Organisation | Edwards Lifesciences Corporation |
| Country | United States |
| Sector | Private |
| PI Contribution | knowledge advice |
| Collaborator Contribution | advice expertise |
| Impact | multidisciplinary engineering , mediicne |
| Start Year | 2016 |
| Description | IKC POC095 - Epiphron Limited/Zinc Ventures |
| Organisation | Zinc Ventures Limited |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Facilities and expertise |
| Collaborator Contribution | Hayley Collen (Director at Epiphron Limited or Venture Partner/ Mentor at Zinc VC) joined as project partner in Sep 2021. We have monthly partner meetings. Hayley provides advice and supports on the commercialisation of this project including project management, funding application, and attracting private investment. We have worked together on the Sliver Linings Business Plan Competition application and the project was successfully shortlisted and awarded with The People's Choice Award. |
| Impact | We have worked together on the Sliver Linings Business Plan Competition application and the project was successfully shortlisted and awarded with The People's Choice Award. |
| Start Year | 2021 |
| Description | IPB University (Indonesia) |
| Organisation | IPB University |
| Country | Indonesia |
| Sector | Academic/University |
| PI Contribution | Knowledge and facilities |
| Collaborator Contribution | Knowledge and facilities |
| Impact | University of Nottingham working with IPB University (Indonesia) on knowledge transfer of microsphere manufacturing processes. |
| Start Year | 2020 |
| Description | LTHT |
| Organisation | Leeds Teaching Hospitals NHS Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | research |
| Collaborator Contribution | facilities, materials implants data |
| Impact | engineering medicine |
| Start Year | 2016 |
| Description | Medacta industry relationship |
| Organisation | Medacta |
| Country | Switzerland |
| Sector | Private |
| PI Contribution | CDT Student at University of Leeds Institute of Medical and Biological Engineering |
| Collaborator Contribution | Raw materials, visits to Medacta, internship in Summer 2020 and support from their engineers in this project |
| Impact | During the initial period of the iSMART project our team has revisited a number of design criteria based on the legislation and Medical Devices regulations. This with input from our Industrial collaborators Medacta has resulted in the project aiming to achieve a device intended to be placed centrally within the polyethylene insert. A number of experiments have shown that the measurement of forces using this novel approach is possible. We have selected and individually tested electrical components that will make the overall device possible within the confined space allowed/possible. Having tested these as a macro prototype circuitry the next stage will be to scale down the size of the electrical circuitry through PCB board design and testing. |
| Start Year | 2019 |
| Description | NAMSA |
| Organisation | North American Science Associates Inc |
| Country | United States |
| Sector | Private |
| PI Contribution | In vivo testing of dCell bone to detremine osseointegration and biocompatibility |
| Collaborator Contribution | undertaking research work |
| Impact | pubication |
| Start Year | 2015 |
| Description | NHSBT |
| Organisation | NHS Blood and Transplant (NHSBT) |
| Department | National Blood Service |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Research |
| Collaborator Contribution | funding, materials and time |
| Impact | publications multidisciplinary engineering biology |
| Start Year | 2016 |
| Description | National Blood Service |
| Organisation | NHS Blood and Transplant (NHSBT) |
| Department | National Blood Service |
| Country | United Kingdom |
| Sector | Public |
| Start Year | 2003 |
| Description | Neotherix |
| Organisation | Neotherix Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Repair of oral and peridontal defects using regenerative and antibacterial strategies delivered by a novel tissue scaffold vehicle Polymeric scaffolds functionalised for periodontal repair |
| Collaborator Contribution | materials |
| Impact | multidisciplinary |
| Start Year | 2015 |
| Description | New collaboration with Prof Olivo Sandro at UCL (POC041- J Dudhia) |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Exploring potential for combining Raman spectroscopy with x-ray phase contrast imaging of cartilage |
| Collaborator Contribution | Bringing expertise in x-ray phase contrast imaging |
| Impact | None as yet |
| Start Year | 2018 |
| Description | Onoging link with NuVision Biotherapies Ltd |
| Organisation | NuVision |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Research facilities and knowledge |
| Collaborator Contribution | Manufacturing facilities and knowledge |
| Impact | None stated |
| Start Year | 2016 |
| Description | PBC Biomed |
| Organisation | PBC Biomed |
| Country | Ireland |
| Sector | Private |
| PI Contribution | None stated |
| Collaborator Contribution | Letter of support |
| Impact | The industrial partner, PBC Biomed, is involved in accelerating the translation and commercial development of the medical device technology |
| Start Year | 2019 |
| Description | POC 60 (Miller) - Cardiff University |
| Organisation | Cardiff University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Visiting PDRA trained on ex vivo model at Cardiff University |
| Collaborator Contribution | Knowledge and facilities |
| Impact | Alistair Sloan: Cardiff, CA in place July 2018, PDRA trained on ex vivo model at Cardiff University July 2019 and subsequently set up the model at Sheffield (output?). Both departments were dental schools. I would say the collaboration has ended, but we would still collaborate when and if needed. |
| Start Year | 2018 |
| Description | POC 69 (Herrick) - Manchester Biogel, mesh implant development |
| Organisation | Manchester BIOGEL |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Knowledge exchange |
| Collaborator Contribution | £79,000 and mesh implant provided in-kind from Manchester Biogel |
| Impact | Developed mouse model Published related findings using an exvivo human peritoneum model to assess mesh material in terms of cytokine production - Pengelly et al. (2019) |
| Start Year | 2018 |
| Description | POC 71 (Miller) - collaboration with Prof Richard Oreffo |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Knowledge and facilities - ex vivo bone regeneration study (at Southampton) from Feb 18th-28th 2019 |
| Collaborator Contribution | Knowledge and facilities |
| Impact | Our enhanced granules demonstrated a significant increase in bone regeneration compared to standard granules in this study. In future, the ex vivo model could be translate to The University of Sheffield, however would require licenses to sacrifice the animals. The results from this project enabled a new collaboration to be formed with The University of Nottingham to (successfully) apply for funding: |
| Start Year | 2019 |
| Description | Paul Rooney (NHSBT Tissue & Eye Services) |
| Organisation | NHS Blood and Transplant (NHSBT) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | See outputs |
| Collaborator Contribution | See outputs |
| Impact | Ongoing collaboration with NHS Blood & Transplant Tissue & Eye Services (Prof Paul Rooney) on translation of decellularised tissues into the clinic |
| Start Year | 2019 |
| Description | Renishaw Plc |
| Organisation | Renishaw PLC |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Secondment project for Dr Riana Guifulina |
| Collaborator Contribution | Consultancy and advice on probe development or of existing technology that may be suited for our purposes. They will also provide advice and knowhow on one of their latest small footprint Raman instruments to link up with a fibre optic probe. We are aiming to pursue these directions once we renew our formal collaboration agreement with Renishaw |
| Impact | Through our collaboration with Professor Geraint we established interactions to fund and organise a secondment project for Dr Riana Guifulina to validate cartilage spectra on their new mapping Raman instrument. This was established through a NDA between all parties. We will next discuss a potential collaboration to test fibre optic probes for clinical applications |
| Start Year | 2019 |
| Description | Sheffield Children's Hospital |
| Organisation | Sheffield Children's Hospital |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Dr Amaka Offiah (Consultant Paediatric Radiologist) |
| Collaborator Contribution | Dr Offiah has attended 2 x quarterly project meetings (first and last) and provided comments. |
| Impact | Reviewed and approved the VERDICT mock-up |
| Start Year | 2017 |
| Description | Sheffield Teaching Hopsitals NHS Foundation Trust |
| Organisation | Sheffield Teaching Hospitals NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | IKC POC0053 - Dr Nicola Peel, Prof Richard Eastell, Professor Eugene McCloskey, Dr Jennifer Walsh, Dr Mary Bull (Consultants in Metabolic Bone Disease) Dr Sarah Gowlett (Consultant Musculoskeletal Radiologist) |
| Collaborator Contribution | Interviews, working groups. |
| Impact | Mock-up of an automated vertebral fracture identification tool presented to Radiologists (Dr Sarah Gowlett) in Sheffield (14 Feb 2018). |
| Start Year | 2017 |
| Description | Simsol2016 |
| Organisation | Simulation Solutions |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Research |
| Collaborator Contribution | equipment , staff time, expertise |
| Impact | multidisciplinary engineering medicine |
| Start Year | 2016 |
| Description | Supply of GMP Collagen |
| Organisation | Collagen Solutions |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Information of collagen materials manufacturing |
| Collaborator Contribution | FoC supply of commercial grade GMP collagen |
| Impact | Manufacture of collagen fibres and gels |
| Start Year | 2014 |
| Description | Tissue |
| Organisation | Tissue Regenix Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Research |
| Collaborator Contribution | materials |
| Impact | multidisciplinary engineering biology |
| Start Year | 2016 |
| Description | Tissue Regenix Ltd |
| Organisation | Tissue Regenix Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | research |
| Collaborator Contribution | materials Ip |
| Impact | papers |
| Start Year | 2014 |
| Description | Vascutec |
| Organisation | Vascutek Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Heart valve conduit |
| Start Year | 2010 |
| Description | Xiros Ltd (including support for CDT studentship) |
| Organisation | Xiros Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Expertise in method development for evaluation of repair materials for ankle ligaments |
| Collaborator Contribution | Access to data and input from industrial and clinical perspectives |
| Impact | To date, abstracts at the British Orthopaedic Research Society meeting. Publications under review - not yet published. |
| Start Year | 2016 |
| Description | collaboration with Prof Geraint Thomas at UCL |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-investigators on new grants - BBSRC (£350,000) and UCLB (£62,000) |
| Collaborator Contribution | Expertise in Raman spectroscopy and industry links |
| Impact | Co-investigators on new grants - BBSRC (£350,000) and UCLB (£62,000) |
| Start Year | 2017 |
| Description | invibio 2016 |
| Organisation | Invibio |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | research |
| Collaborator Contribution | funds, time, materials |
| Impact | multidiciplinary |
| Start Year | 2016 |
| Description | invibio 2016 |
| Organisation | Invibio |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | research |
| Collaborator Contribution | funds, time, materials |
| Impact | multidiciplinary |
| Start Year | 2016 |
| Title | COMPOSITE BONE IMPLANTS |
| Description | The invention provides natural multi-composite bone implants such as bone-connective tissue-bone and osteochondral implants for the replacement and/or repair of, for example and in particular a damaged or defective bone-meniscus-bone joint or a bone-patella tendon-bone joint or osteochondral lesions, methods of preparing the composites and uses thereof. The invention also provides natural or native composite bone-connective tissue- bone and osteochondral matrices or scaffolds that are substantially decellularised for subsequent transplantation/implantation. |
| IP Reference | WO2014037713 |
| Protection | Patent application published |
| Year Protection Granted | 2014 |
| Licensed | No |
| Impact | Proof of concept phase in large animal model completed for bone-tendon-bone, discussions ongoing with a company on development re licensing |
| Title | Corneal tissue |
| Description | Corneal tissue - filed 13 November 2019 |
| IP Reference | GB1916506.7 |
| Protection | Patent application published |
| Year Protection Granted | |
| Licensed | No |
| Impact | Not known |
| Title | IKC POC059 UOL (Jha) - Hydrogel Formulation |
| Description | https://patents.google.com/patent/US20170304156A1/en |
| IP Reference | US20170304156A1 |
| Protection | Patent application published |
| Year Protection Granted | 2017 |
| Licensed | Commercial In Confidence |
| Impact | https://patents.google.com/patent/US20170304156A1/en |
| Title | IMPROVEMENTS IN AND RELATING TO COLLAGEN BASED MATERIALS |
| Description | https://patents.google.com/patent/EP2976112B1/en?inventor=Giuseppe+TRONCI |
| IP Reference | EP2976112 |
| Protection | Patent granted |
| Year Protection Granted | 2016 |
| Licensed | No |
| Impact | None stated |
| Title | NOVEL PEPTIDE COMPLEXES |
| Description | The invention relates to novel self-assembling peptide complexes comprising a charged peptide and a polysaccharide, methods of producing them and uses therefor. The novel self-assembling peptide complexes of the present invention have particular utility in the restoration of biomechanical or biochemical function of a variety of biological tissues, for example and without limitation, in degenerated spinal discs, osteoarthritic joints, damaged cartilage, meniscus, ligaments, tendons, dental, ophthalmic and cardiovascular and blood vessel tissues. The invention provides inter alia methods of repairing and or restoring biomechanical or biochemical function of biological tissues and scaffolds for the support of cell growth. |
| IP Reference | US2016058871 |
| Protection | Patent granted |
| Year Protection Granted | 2016 |
| Licensed | No |
| Impact | Follow on funding obtained for first in vivo study |
| Title | SOLID SUSPENSION |
| Description | A solid suspension for use in bone regeneration and/or the repair of bone defects, comprising a source of at least one group II metal cation and a source of zinc cations, wherein the source of zinc cations comprises zinc oxide and wherein where there is only one group II metal cation this is strontium. A bone graft comprising a solid suspension, a method of preparation of a solid suspension and a use of a solid suspension in bone regeneration and/or in the repair of bone defects. |
| IP Reference | WO2020044028 |
| Protection | Patent application published |
| Year Protection Granted | 2020 |
| Licensed | Commercial In Confidence |
| Impact | None known 09/03/2021 |
| Title | Theagen(TM) Granted (Sidney POC064) |
| Description | Trademark for Theagen(TM) name granted (Sidney POC064) |
| IP Reference | |
| Protection | Trade Mark |
| Year Protection Granted | 2018 |
| Licensed | No |
| Impact | Trademark for Theagen(TM) name granted |
| Title | VERDICT |
| Description | The current version of the prototype for 3D vertebral reconstruction and fracture assessment include method implementation and interface design (Frangi et al). It will be progressively updated until the last prototype version at the end of the project. SEP 18 Started the development of the graphical interface for VERDICT |
| IP Reference | |
| Protection | Copyrighted (e.g. software) |
| Year Protection Granted | 2018 |
| Licensed | No |
| Impact | The current version of the prototype for 3D vertebral reconstruction and fracture assessment include method implementation and interface design (Frangi et al). It will be progressively updated until the last prototype version at the end of the project. SEP 18 Started the development of the graphical interface for VERDICT |
| Title | Arthroscopic device for stimulating synovial mesenchymal stem cells in the knee |
| Description | The arthroscopic device is currently (as of Jan 2017) in a small scale clinical evaluation study at Leeds Teaching Hospitals funded through NIHR funded Leeds Musculoskeletal Biomedical Research Unit, led and managed by Prof Dennis McGonagle, Dr Tom Baboolal with Consultant Mr Owen Wall. |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Early clinical assessment |
| Year Development Stage Completed | 2017 |
| Development Status | Actively seeking support |
| Impact | IKC funded Proof of Concept (POC) Project supported early development of the new medical device. This supported device design and testing, prototype manufacture and subsequent manufacture of devices for use in the clinical evaluation. The POC also supported generation of data used in patent filing. |
| Title | Automated Identification of Osteoporotic Vertebral Fractures: VERDICT |
| Description | A standard computerised approach that can reliably detect and analyse spinal fractures in patients with osteoporosis First Verdict prototype for clinical testing, and user interface mockup (V6) Also developed video mock-up for More efficient communication. 2nd prototype ongoing |
| Type | Diagnostic Tool - Imaging |
| Current Stage Of Development | Early clinical assessment |
| Year Development Stage Completed | 2018 |
| Development Status | Under active development/distribution |
| Impact | Unknown (11/03/2019) |
| Title | Novel crosslinked chitosan/PNIPAAM hydrogel loaded with positively charged RALA/hydroxyapatite NPs for bone regeneration (McCarthy POC068) |
| Description | Novel crosslinked chitosan/PNIPAAM hydrogel loaded with positively charged RALA/hydroxyapatite NPs for bone regeneration |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Refinement. Clinical |
| Year Development Stage Completed | 2018 |
| Development Status | Under active development/distribution |
| Impact | Novel crosslinked chitosan/PNIPAAM hydrogel loaded with positively charged RALA/hydroxyapatite NPs for bone regeneration |
| Title | POC052- Perry |
| Description | Osteoarthritis is a painful condition that affects joints, where the surfaces within the joints become damaged so they don't move as smoothly as they should. The most commonly identified cause of osteoarthritis in patients under 60 years old is a condition called developmental dysplasia of the hip, where the hip doesn't develop properly from birth. However, if diagnosed early, this condition is easily treatable and can prevent osteoarthritis from developing later in life. The SHINE study: Screening The Hips In NEwborns aims to develop an acoustic test to detect developmental dysplasia of the hip in newborn babies. |
| Type | Diagnostic Tool - Non-Imaging |
| Current Stage Of Development | Initial development |
| Year Development Stage Completed | 2018 |
| Development Status | Under active development/distribution |
| Impact | - |
| Title | POC073 A novel Sensory Training System for the potetnial reduction of pain |
| Description | A novel Sensory Training System for the potetnial reduction of pain is currently going through clinical pilot testing of revised hardware and software. The device is used within a patient's home. Recruitment started Sept 2021 and projected to run until November 2022. |
| Type | Therapeutic Intervention - Medical Devices |
| Year Development Stage Completed | 2022 |
| Development Status | Under active development/distribution |
| Impact | No other notable impacts. |
| Title | Porcine Acellular Bladder Matrix biomaterial - (POC045 - Southgate) |
| Description | The device has undergone auto-augmentation bladder surgery in a porcine pre-clinical trial. The surgery was successful and qualitative analysis of tissue healing shows the device to be successful. Further quantitative analysis is on-going. This project has been funded via IKC POC funding £100k(FeC). The collaborative company Tissue Regenix will be approached for further support of the technology development. |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Initial development |
| Year Development Stage Completed | 2017 |
| Development Status | Under active development/distribution |
| Impact | This device has many possible clinical applications due to unique elastic/ flexible properties and the apparent success at which the device has been shown to promote urinary tissue integration on healing. The primary application under investigation is for paediatric auto-augmentation bladder surgery. There are currently no suitable products on the market to address this clinical need. It is anticipated that, if satisfactorily addressed, this technology could provide a life-long solution for paediatric patients requiring this complex surgery. |
| Title | Raman arthrospectroscopy for intra-operative mapping of early articular articular cartilage damage (J. Dudhia PO041) |
| Description | Raman arthrospectroscopy for intra-operative mapping of early articular articular cartilage damage is being developed in by Dr J. Dudhia at RVC and Prof P. McMillan at UCL. This technology is currently in Proof of concept stage in development and is funded through Arthritis Research UK (Versus Arthritis) in collaboration with the IKC. The POC project aims to improve the signal to noise, reduce imaging time and produce a commercialisable prototype. |
| Type | Diagnostic Tool - Imaging |
| Current Stage Of Development | Initial development |
| Year Development Stage Completed | 2016 |
| Development Status | Under active development/distribution |
| Impact | The research team are actively developing collaborations with commercial organisations and are developing partnership with Renishaw to provide the small diameter fibre optic Raman probe. |
| Title | TOKA high tibial osteotomy plate and surgical guides |
| Description | In silico clinical trials completed and currently securing funding and ethical approval for first in man clinical trials. |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Refinement. Clinical |
| Year Development Stage Completed | 2018 |
| Development Status | Under active development/distribution |
| Impact | Device and company have undergone MHRA registration and company has completed ISO:13845 BSI accreditation |
| Title | acellular bone |
| Description | under development and in in vivo trials |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Refinement. Non-clinical |
| Year Development Stage Completed | 2014 |
| Development Status | Under active development/distribution |
| Impact | under development and in animal trials |
| Title | acellular bone cartilage osteochondral graft |
| Description | under development |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Initial development |
| Year Development Stage Completed | 2014 |
| Development Status | Under active development/distribution |
| Impact | under developemnt |
| Title | acellular bone cartilage osteochondral graft |
| Description | under development NHSBT |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Initial development |
| Year Development Stage Completed | 2015 |
| Development Status | Under active development/distribution |
| Impact | under development |
| Title | acellular bone patellar bone graft |
| Description | under development by NHSBT |
| Type | Therapeutic Intervention - Surgery |
| Current Stage Of Development | Refinement. Non-clinical |
| Year Development Stage Completed | 2014 |
| Development Status | Under active development/distribution |
| Impact | under development by NHSBT |
| Title | acellular dcell vascular patch |
| Description | licensed to and commercialised by Tissue Regenix |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Small-scale adoption |
| Year Development Stage Completed | 2010 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | First dcell clinical product |
| URL | https://clinicaltrials.gov/show/NCT00958230 |
| Title | acellular dcell dermis |
| Description | commercialised by Tissue regenix from 2014 |
| Type | Therapeutic Intervention - Medical Devices |
| Year Development Stage Completed | 2014 |
| Development Status | Under active development/distribution |
| Impact | sold and distributed in USA |
| Title | acellular dermis |
| Description | supplied as clinical product by NHSBT |
| Type | Therapeutic Intervention - Surgery |
| Current Stage Of Development | Small-scale adoption |
| Year Development Stage Completed | 2014 |
| Development Status | Under active development/distribution |
| Impact | supplied by NHSBT, improved wound healing in chronic leg ulcers |
| Title | acellular heart valve |
| Description | clinical application through human tissue bank |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Small-scale adoption |
| Year Development Stage Completed | 2010 |
| Development Status | Under active development/distribution |
| Impact | proof of clinical use acellular technology |
| Title | acellular vascular graft |
| Description | under development by NHSBT and Tissue Regenix |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Refinement. Non-clinical |
| Year Development Stage Completed | 2014 |
| Development Status | Under active development/distribution |
| Impact | Under development by NHSBT an dTissue Regenix |
| Title | dcell ligament |
| Description | Under commercial development by tissue Regenix, progressing to CE mark and product launch |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Refinement. Non-clinical |
| Year Development Stage Completed | 2014 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | under commercial development by Tissue Regenix in clinical trial started 2015 proceeding to Ce mark and product launch 2017 |
| URL | https://clinicaltrials.gov/show/NCT02540811 |
| Title | dcell meniscus |
| Description | Developed by tissue Regenix In clinical trial started 2015 |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Late clinical evaluation |
| Year Development Stage Completed | 2014 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | first in man clinical trial started 2015 |
| URL | https://clinicaltrials.gov/show/NCT02270905 |
| Title | iSMART - Instrumented Sensor Module for Arthroplasty Treatment |
| Description | The iSMART (Instrumented Sensor Module for Arthroplasty Treatment) will offer early detection of poorly performing implants, through changes in force, motion and temperature revolutionising how patients interact with their recovery, providing a means to collect, access and analyse meaningful data remotely and intervene as appropriate. This will provide improved post-operative care with greater convenience to the patient and reduced burden on healthcare services |
| Type | Therapeutic Intervention - Medical Devices |
| Year Development Stage Completed | 2019 |
| Development Status | Under active development/distribution |
| Impact | iSMART device incorporates measurements that will be useful as a diagnostic tool in Total Knee Replacement performance in vivo. Testing has shown that a novel approach of measuring forces centrally within a polethylene component of a TKR can provide useful information. iSMART will be a medical device intended for incorporation/inclusion in current technology i.e. TKR implanted during Surgery. This will aid in the recovery process (therapeutic) as well as in behavioural risk modification. The potential data collected by the iSMART device will be of great benefit to the development of TKR Designs in the future. |
| Title | New method for quantitative image analysis |
| Description | Researcher working on POC project worked with company, TissueGnostics, to develop new quantitative image analyses |
| Type Of Technology | New/Improved Technique/Technology |
| Year Produced | 2018 |
| Impact | New quantitative image analyses |
| Title | TOKA High tibial Osteotomy Software prototype |
| Description | The software package supports the development and planning of personalised high tibial osteotomy device, accurate surgical cutting jig and aids in planning the surgical procedure to ensure successful outcomes. It will improve and make the surgery more accurate while also easier to perform and save time. |
| Type Of Technology | New/Improved Technique/Technology |
| Year Produced | 2018 |
| Impact | makes the operation easier for surgeons to perform. Personalised cutting guides and fixation plates will improve accuracy and surgical outcome. The software, cutting guide and fixation plate will reduce operation times. It is expected to benefit patients by improving knee osteoarthritis symptoms, provide an alternative to total knee replacement and solves many of the issues currently observed with HTO currently. |
| Title | ankle joint simulator |
| Description | ankle joint simulator |
| Type Of Technology | Physical Model/Kit |
| Year Produced | 2015 |
| Impact | support product development |
| Title | finite element simulation tools to capture patient variation for the analysis of orthopaedic devices across a patient cohort |
| Description | This project has been led by Dr Ruth Wilcox in partnership with Simpleware Limited. The development of the software add-on has been completed and the final validations with the Leeds data set-set are coming to an end. It is anticipated that a technology demonstrator project will now be undertaken with a company that can demonstrate the utility of the software for evaluating spinal implants. The commercial team is now engaged and discussions with Simpleware around a possible license deal are on-going. It is envisaged that as part of this license deal Simpleware will engage Leeds expertise as part of their offer to companies. In addition Leeds personnel will retain the right to undertake consultancy in their own capacity. |
| Type Of Technology | Software |
| Year Produced | 2013 |
| Impact | further research |
| Title | hip joint simulator |
| Description | hip joint simulator |
| Type Of Technology | Physical Model/Kit |
| Year Produced | 2012 |
| Impact | commercial product Simulation solutions |
| Title | knee joint simulator |
| Description | knee joint simulator |
| Type Of Technology | Physical Model/Kit |
| Year Produced | 2013 |
| Impact | Commercial product simulation solutions |
| Title | natural hip simulator |
| Description | natural hip simulator |
| Type Of Technology | Physical Model/Kit |
| Year Produced | 2014 |
| Impact | commercial product simulation solutions |
| Title | natural knee simulator |
| Description | natural knee simulator |
| Type Of Technology | Physical Model/Kit |
| Year Produced | 2013 |
| Impact | commercialised by simulation solutions |
| Title | patellar simulator |
| Description | patellar femoral joint simulator |
| Type Of Technology | Physical Model/Kit |
| Year Produced | 2009 |
| Impact | Support for new product development |
| Company Name | CELL LANE LIMITED |
| Description | Cell Lane Ltd develops a cell isolation and separation platform. The platform offers assistance in the treatment of chronic diseases such as cancer and AIDS, and is intended to enable new fields of research in research activities, such stem cell research. The company was incorporated in 2017 and is based in Chester, United Kingdom. |
| Year Established | 2017 |
| Impact | 16/07/2019 |
| Company Name | ADDITIVE INSTRUMENTS LIMITED |
| Description | manufactures surgical instruments by additive manufacture |
| Year Established | 2019 |
| Impact | None recorded |
| Website | https://www.additiveinstruments.com/ |
| Description | 'Be Curious' University of Leeds Public Engagement event |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Science fair style activities demonstrating the research on-going within the institute, primarily focussed on total joint replacement. 10 research staff and post-doctoral students engaged with members of the general public through this one-day event |
| Year(s) Of Engagement Activity | 2016 |
| Description | 30th Annual Meeting of the Wound Healing Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation by Dr. Tronci on Photoactive Type I (atelo) collagen as Building Blocks of Advanced Wound Dressings |
| Year(s) Of Engagement Activity | 2018 |
| Description | 3D DTA training course |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Workshop for PhD students from doctoral training alliance on 3D cell culture, lead to other collaborations and supporting students around the country |
| Year(s) Of Engagement Activity | 2019 |
| Description | 3D MedLIVE |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A partnership between 3DMedNet and the Journal of 3D Printing in Medicine. The event convenes members of the community who, together, can make 3D printing in surgical practice an everyday reality in many hospitals. Case studies from pioneering surgeons and researchers who are already utilising this technology in their practice, plus panel discussions and roundtables with regulators, manufacturers and funders. |
| Year(s) Of Engagement Activity | 2019 |
| Description | 3D-printed implants and scaffold technology - how bioengineering innovation could treat and prevent osteoarthritis |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Online news article as part of Arthritis Research UK's Arthritis Today Winter 2017 no.174 |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.arthritisresearchuk.org/news/arthritis-today/2017/november/3d-printed-implants-and-scaff... |
| Description | 5 of the Coolest MedTech Inventions from the Leeds City Region. |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | My work on a healing wound dressing featured by Leeds List on 12 January 2022: 5 of the Coolest MedTech Inventions from the Leeds City Region. |
| Year(s) Of Engagement Activity | 2022 |
| Description | ACPGB&I Anastomotic leak webinar |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Webinar on anastomotic leak to professional UK association, highlighting the IntAct study. Approx 75 attendees. |
| Year(s) Of Engagement Activity | 2021 |
| Description | ARUK Arthritis Today - 3D-printed implants and scaffold technology |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Continuing collaboration with ARUK (now Versus Arthritis). Website article highlighting two case studies where Arthritis Research UK has invested in innovative research dedicated to developing medical technologies: At UCL - a scaffold type device which can be implanted into a damaged joint to create an environment in which cartilage can reform The development of ToKa®: A High Precision Patient Specific High Tibial Osteotomy Procedure at the University of Bath |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.arthritisresearchuk.org/news/arthritis-today/2017/november/3d-printed-implants-and-scaff... |
| Description | ARUK Winter Warmer |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Fundraising leaflet in collaboration with ARUK (now Versus Arthritis) |
| Year(s) Of Engagement Activity | 2017 |
| Description | Activity stand at Manchester community science festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Manchester community science festival, put on an activity stand |
| Year(s) Of Engagement Activity | 2019 |
| Description | Alex Frangi Chair Announcement |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Article on University of Leeds website about the Chair in Emerging Technologies awarded to Professor Alex Frangi by the Royal Academy of Engineering. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.leeds.ac.uk/news/article/4403/using_virtual_populations_to_create_safer_medical_devices?... |
| Description | Announcement of Proof of Concept project -Colorectal HTC website & newsletters (POC046 - Jayne) |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A press release detailing a proof of concept project, in collaboration with an industrial partner, would seek to address a life threatening unmet clinical need related to bowel surgery. This press release was announced in the newsletter and website of the Colorectal Health Technology Cooperative. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://colorectal.htc.nihr.ac.uk/latest-news/colorectal-wound-healing/ |
| Description | Announcement of SIPF seedcorn winners |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | UKRI have now published details of the SIPF Wave 1 bids awarded seedcorn funding. Medical Technologies in the Leeds City Region: Driving economic growth, improving health and care. |
| Year(s) Of Engagement Activity | 2019,2020 |
| Description | Ask the Expert - Clinically Led Manufacture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Four separate presentations given by: - Prof Nikos Donos, Head of the Clinical Oral Research Center at the Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London (QMUL) in collaboration with SJ Russell. - SJ Russell (Leeds) - P Giannoudis (Leeds) - M. Mehr (Geistlich Pharma AG) |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://mede-innovation.ac.uk/event/mede-innovation-ask-expert-oct-18/ |
| Description | Ask the Researcher - Patient Involvement group meeting (Chapel Allerton Hospital, Yorkshire) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Short talk to a patient group focussed on communicating the research of the iMBE ankle research group. Two events were run (lunch time and evening) with approximately 25 patients and interested general public. There was much interest in our research area, and several patients had ankle problems or total ankle replacement. It was hoped there would be some engagement around informing future research directions, although it was clear the patients were less familiar with engineering research. Subsequently I have been awarded an internal engagement fellowship from the university specifically to develop stronger links with the ankle patient group, and to start a dialogue between the research group and patients to have better communication and understanding between the two. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://lmbru.leeds.ac.uk/event/ankles-evening-event/ |
| Description | BEIS Humans of STEM Instagram |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | BEIS launched a new social media channel on Instagram called Humans of Stem. A photo blog and highlight key projects with the aim of helping the public better understand what motivates researchers/academics/businesses, and how the complex projects they work on. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Back 2 the Future: Cells and Gels for LBP. C Le Maitre: Cafe Sceinctific - Scunthorpe 6th March 2019: Cells and gels for LBP. (POC057 SHU) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Cafe Scientific meeting in Scunthorpe 6th March 2019 on Cells and gels for LBP. |
| Year(s) Of Engagement Activity | 2016,2019 |
| Description | Back Pain Patient User Group |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | patient user group meeting for patients with LBP, current research avenues within the group discussed and patients shared their lived experiences |
| Year(s) Of Engagement Activity | 2020 |
| Description | Bio engineering event |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | presentation and lab tour - number individuals contacted after saying had opened minds and asked for other info |
| Year(s) Of Engagement Activity | 2019 |
| Description | British Orthopaedic Association (BOA) Annual Conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Engagement of clinicians and industry |
| Year(s) Of Engagement Activity | 2015 |
| Description | British Orthopaedic Research Society, Leeds 2018 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Support provided for BORS 2018 - With over 600 members involved in research, this meeting will include a mixture of clinical and scientific sessions, with speakers from across the UK, showcasing the latest leading research going on in our laboratories and clinics. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.imbe.leeds.ac.uk/bors-2018/ |
| Description | C Le Maitre: Manchester SciBar public talk 29th Nov 2018 (POC057 SHU) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | public talk on research related to POC project |
| Year(s) Of Engagement Activity | 2018 |
| Description | Cafe Scientific - Scunthorpe |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Café scientific presentation discussing the research and the reasons for low back pain. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Cartilage and Osteoarthritis Workshop - Focus on Imaging reservation University of Exeter, 18 Spetember 2018; Dr Jay Dudhia Chair by invitation (POC041 J Dudhia) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cartilage and Osteoarthritis Workshop - Focus on Imaging |
| Year(s) Of Engagement Activity | 2018 |
| Description | Clinical Focus Group (Sidney POC064) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Clinical focus group held at QVH in East Grinstead. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Digital Health Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | The workshop will explore unmet needs in self-monitoring and managing long term health conditions (asthma, diabetes, COPD), and will focus on developing initial solutions to address the identified unmet needs. Following the workshop, the Translate team will support project teams in progressing their ideas by providing: initial funding, access to expertise, extra clinical/NHS input, project development planning, support with further investment etc. The workshop provides the opportunity for healthcare professionals, NHS/CCG representatives, academics, companies, and sufferers of long term health conditions to co-develop solutions which respond to real national health needs. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Digital Healthcare Revolution: Harnessing NHS Technology |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | At the Digital Healthcare Revolution: Harnessing NHS Technology conference we will discuss the role that technology and data is already playing within the NHS and how future digital innovation will enable the changing landscape of the health and social care system. The speaker programme of leading experts will share knowledge and exchange opinion on how the progressive and sustained use of digital technologies can benefit a transformed healthcare system. With vertical integration an ambition across the NHS and social care there will be an opportunity to examine how paperless information can be shared appropriately and safely to the benefit of patients and staff. We will showcase a number of initiatives and examples of best practice from throughout the health and social care system and there will be ample opportunity for interactive discussion and networking amongst fellow professionals and peers. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Early Career Researcher 2 day residential 'Sandpit' workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | This 2 day workshop was a forum for Early Career Researchers (ECR) to discuss and share potential research opportunities with a view to pitching for £5000 (FEC) funding from MeDe Innovation to undertake the chosen projects. Projects had to be a collaboration between at least two Universities/companies. ECR's were also given presentations on various aspects of professional development, such as grant writing and IP. At the end of the two days, the ECR's pitched ideas to a panel of industry and academic MeDe members and 2 projects were awarded funding to progress. |
| Year(s) Of Engagement Activity | 2016 |
| Description | European Inventor of the Year Announcement |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Website article highlighting the nomination of Eileen Ingham and John Fisher for the EU Inventor of the Year prize in 2018. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://medical-technologies.leeds.ac.uk/news-post/john-fisher-and-eileen-ingham-shortlisted-for-an-i... |
| Description | Explore event - 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | explore event in Sheffield, aimed principally at children but wide audience, lots of follow up contacts and questions. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Explore event Sheffield |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Presented within the Sheffield Explore event discussing the research funded by the MRC and sparked lots of interest into what research is undertaken. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Festival of Ideas 2018 (Southgate POC045) |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | The Festival has mostly free events, including talks, performances, exhibitions and family-friendly activities, the Festival delivers an exciting and diverse programme for all ages. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://yorkfestivalofideas.com/2018/ |
| Description | HTCF National Conference Students in Healthcare Innovation |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Healthcare Technologies Co-operative Foundation. Speakers included - Professor Mike Raxworthy, Operations Director of the Regener8 Centre for Translational Regenerative Medicine, Institute of Medical and Biological Engineering, Uni of Leeds. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://leeds.tech/event/htc-foundation-national-conference/ |
| Description | Healthcare Review |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Bridging the Med Tech Innovation Valley of Death - Professor John Fisher, CBE, University of Leeds 24/11/2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | Hosted laboratory visit for Leeds Biomedical Research Centre Patient Public Involvement group |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Hosted a laboratory tour and series of talks from academic members of the Institute of Medical and Biological Engineering for members of the Leeds PPI group |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://youtu.be/cKfs50-NxJQ |
| Description | IKC Annual Conference 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | The conference brings together the IKC's network of academics, industrialists, clinicians and regulatory body representatives through lively presentations and active networking. Sessions include: Updates from our most successfully translated projects Presentations from our partner programmes, including funding opportunities available A dedicated Early Career Researcher session discussing career paths |
| Year(s) Of Engagement Activity | 2019 |
| Description | IKC E-Shot Regener8 IKC Annual Conference - Call for community sourced session |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | IKC-Regener8 requesting a call for 'community sourced' session presentations, developing new relationships and profiling the lastest research within the Med Tech industry. The impact of this E-shot provided applications for submission and review. |
| Year(s) Of Engagement Activity | 2016 |
| Description | IKC E-shot rowdsourcing Competition + ARUK Call Sent on 16 May 2016 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | E-shot promoting two translational funding competitions supported by the IKC, including Arthritis Research UK Translational Proof of Concept Funding and IKC ranslational Feasibility Fund. |
| Year(s) Of Engagement Activity | 2016 |
| Description | IKC E-shot Crowdsourcing Competition, Sent on 6 Apr 2016 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | IKC E-shot promoting the IKC led Crowdsourcing Competition, Funding for Feasibility Studies, offering three university-based researchers a chance to have a feasibility study funded (up to £10,000 per study) and supported by professionals in research translation. |
| Year(s) Of Engagement Activity | 2016 |
| Description | IKC Industry Partnership Call Industry Final Wave |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Engaged a total of 1,054 IKC contacts promoting the IKC Translational POC industry partnership call. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://medical-technologies.leeds.ac.uk/current-call/apply-for-translational-proof-of-concept-fundin... |
| Description | IKC Industry Partnership Call Industry Reminder Sent on 3 Nov 2016 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | E-shot sent on 3 Nov 2016 to 134 industry unique subscribers to promote the IKC Industry POC. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://medical-technologies.leeds.ac.uk/current-call/apply-for-translational-proof-of-concept-fundin... |
| Description | IKC Newsletter including funding digest September 2016 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Our newsletter features 6-8 of our key news items/events over a three month period, and is circulated to our entire contacts list and also pushed out via the website, twitter and LinkedIn pages. The content included promotion for the upcoming IKC-Regener8 conference, IKC POC funding calls and partner news. |
| Year(s) Of Engagement Activity | 2016 |
| Description | IKC POC Briefing Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Academics and researchers working in close collaboration with medical technology industry partners can apply for £100,000 FEC from the Medical Technologies IKC to undertake proof of concept projects in Regenerative Medical Devices & Medical Devices with Enhanced Regenerative Functions. - See more at: http://medical-technologies.leeds.ac.uk/event/ikc-translational-proof-of-concept-awards-briefing-launch-and-qa/#sthash.DMSSCXC8.dpuf |
| Year(s) Of Engagement Activity | 2016 |
| Description | IKC POC0053 - Mock-up presented to Lay Panel |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Progress report presented to Lay Panel (18 Oct 2018). Demonstration of mock-up of automated vertebral fracture identification tool. Positive reception. |
| Year(s) Of Engagement Activity | 2018 |
| Description | IKC POC0053 - Mock-up presented to Radiologists |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Mock-up of automated vertebral fracture identification tool presented to Radiologists (Dr Sarah Gowlett) in Sheffield |
| Year(s) Of Engagement Activity | 2018 |
| Description | IKC POC0053 Interviews with Clinicans from MBC |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Interviews with clinicians from MBC Dr Peel - 24.10.17 Prof Eastell 5.12.17 Regular MBC doctors meeting 11.12.17 |
| Year(s) Of Engagement Activity | 2017 |
| Description | IKC POC0053 Sheffield lay Advisory panel |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Lay Panel introduced to the project - automated vertebral fracture identification tool (20.04.2017) and progress report presented (19.10.17) |
| Year(s) Of Engagement Activity | 2017 |
| Description | IKC POC067 - Guest speaker at University of Strathclyde (online via Zoom) on the topic of decellularised tissues (24/02/22) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Guest speaker at University of Strathclyde (online via Zoom) on the topic of decellularised tissues (24/02/22) |
| Year(s) Of Engagement Activity | 2022 |
| Description | IKC POC068 - Hosted a bio-engineering undergraduate student from Strathclyde University in my laboratory from June - Sept 2021 |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Undergraduate students |
| Results and Impact | The student in question had no experience of wet lab work after completing his first year remotely. This gave him the opportunity to learn about key lab skills by doing and the feedback is that he was very well prepared for being in practical year 2 classes. |
| Year(s) Of Engagement Activity | 2021 |
| Description | IKC POC068 - International Women's Day event at Catalyst Inc. Titanic Quarter, Belfast _ Women in STEM |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | 08 March 2022, primarily local but catalyst expanded to all their networks. Event was designed to interrogate the key skills that women in STEM need and how can we encourage more women into this field. Too early to determine the outcome. |
| Year(s) Of Engagement Activity | 2022 |
| Description | IKC POC068 - Science at Queen's 4 March 2021 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | This was a widening participation event to all sixth formers in Northern Ireland where we explained what you can do with individual subjects at A-level and how they can merge together into translational healthcare research. The Most significant outcome was student engagement, helping QUB to develop its civic responsibility and inspiring some students to consider careers in this space. |
| Year(s) Of Engagement Activity | 2021 |
| Description | IKC POC084 - IF Oxford Science Festival |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Our group held a stand on biomaterials and textile technologies exposing our research to 500+ public members. This sparked many questions and discussion about technologies in development. Note: In 2020, the festival was held online. |
| Year(s) Of Engagement Activity | 2019,2020 |
| URL | https://if-oxford.com/about/past-festivals/ |
| Description | IKC POC084 - Termis 2021 virtual congress |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Termis 2021 virtual congress (poster presented online; title: "Assembling an electrospun PCL cord for ligament repair unsing a semi-industrial braiding machine"); The work was also presented at the annual UKRMP conferences 2020 and 2021 (Title: "Electrospun biomaterials for soft tissue repair: an update on their translational journeys to clinics") |
| Year(s) Of Engagement Activity | 2021 |
| Description | IKC POC095 Navigating the funding and investment landscape |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | organiser: Zinc with Community of Practice in UKRI.23th Feb 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | IKC POC095 Silver Linings business pitch competition |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Event: Silver Linings business pitch competition. Presentation title: Empower your knee &move free. Presenter: Aiqin Liu. Date: 10th Februray 2022. I won the People's Choice Award. https://www.silverliningscompetition.com/business-plan/ |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.silverliningscompetition.com/business-plan/ |
| Description | IKC POC095 University of Leeds Michael Beverley Innovation Fellowship |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Publish Date: 4th October 2021. Video title: University of Leeds Michael Beverley Innovation Fellowship. Weblink: https://www.youtube.com/watch?v=MwP3MvbJ-pk. I was interviewed by the University of Leeds as an award holder of Michael Beverley Innovation Fellowship. I talked about this knee device project and shared my experience in leading a commercialisation project as an academic. |
| Year(s) Of Engagement Activity | 2021 |
| Description | IKC POC095 Workshop: Integrated and inclusive care through smart health |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Organiser: Centre for HealthTech Innovation Date: 4 Feb 2022, |
| Year(s) Of Engagement Activity | 2022 |
| Description | IKC POC095 Workshop: Patients focus group meeting in 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Organised by our team and facilited by NIHR Leeds Biomedical Research Centre. 7 knee patients attended the patient focus group meeting. They provided feedback on the device design proposal which helped identify the design priorities. Another patient focus meeting has been schedule in May 2022. |
| Year(s) Of Engagement Activity | 2021 |
| Description | IKC POC095 Workshop: Stratified and precision therapies |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Organiser: Centre for HealthTech Innovation,Date: 27 Jan 2022. Participates for this workshops are academic researchers, clinicians in NHS, people from medical device companies. Two new contacts were made and potential collaboration ideas have been explored during the follow up meetings. |
| Year(s) Of Engagement Activity | 2022 |
| Description | IKC Regener8 Annual Meeting |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Featuring world-class speakers, oral and poster presentation sessions and interactive panel discussions, the Regener8 Annual Conference 2016 will provide an excellent opportunity to disseminate, share and discuss the impact of university-industry collaborations in the field of regenerative therapies and medical technologies. Sessions include: • High calibre, international keynote speaker • Accelerating the development of regenerative devices nationally - presentations from our national partners on their proof of concept projects • Sharing our expertise with other providers - presentations from our Arthritis Research UK funded projects • Question panels • Networking time, including poster presentations from our Early Career Researcher community • Value delivered - presentations from our partners that have successfully delivered IKC POC projects that are progressing closer to clinic and the market Community showcase: presentations from the community that are submitted, selected and delivered by you, the Regener8 and UK med tech community |
| Year(s) Of Engagement Activity | 2016,2017,2018 |
| Description | IKC Translational Feasibility Fund E-Shot Sent on 27 May 2016 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | The Medical Technologies Innovation and Knowledge Centre (IKC) is partnering with Leeds University Business School to open a medical technologies innovation competition to support early stage translational research. E-shot sent to relevant IKC contacts to promote the call. |
| Year(s) Of Engagement Activity | 2016 |
| Description | IKC-Regener8 Annual Conference - Call for community sourced session 24 Jan 2017 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Sent on 24 Jan 2017 to 1,078 unique subscribers to source presentations for the IKC-Regener8 Annual conference 2017. |
| Year(s) Of Engagement Activity | 2016 |
| Description | IKC-Regener8 E-Shot Your chance to present at Regener8/IKC conference 2016, Sent on 26 Feb 2016 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | IKC-Regener8 requesting a call for 'community sourced' session presentations, developing new relationships and profiling the lastest research within the Med Tech industry. The impact of this E-shot provided applications for submission and review. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Impact Event - 18 November 2015 'Investing in Knowledge - creating opportunity' |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The event will: 1) Evidence the scale and breadth of the University's contribution at a national and international level and to demonstrate how this translates into the contribution made to the economy of the City Region (in both absolute and proportionate terms) using a specially commissioned piece of research • Demonstrate tangible examples of the breadth of the University's impact using selected examples of both current and past activity, accessible for a non-academic audience and in so doing positively impact perceptions of the University's scale, breadth and excellence • Showcase specific examples of major new initiatives designed to increase the University's future impact, with the focus being at a regional level (but making it clear that these are nationally and internationally significant activities) - examples would include the North East Quarter, the Academic Health Partnerships, the Cultural Institute and the University Innovation and Enterprise Centre (UIEC); • Set this in the context of the University's strategic ambition • Showcase broader University and campus developments including the campus master plan 2. The event will be positioned as the first of a series of activities that will form a coherent strategy for external stakeholder engagement designed to increase the effectiveness with which the University engages with key stakeholders on a City, regional, national and international basis. Desired Outcomes: To positively impact existing perceptions of key stakeholders so that they gain a sense of the scale, substance and breadth of the University's relative contribution to the region set in the context of its national and global impact. Internationally significant work has a direct regional relevance and impact. This in turn should help support the University and the City and region to work together to maximise the opportunities for funding designed to support local and regional economic growth. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Innovate 2015 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | The global spotlight on UK innovation including attendance from over 3,000+ of the UK's most exciting innovators, international investors and buyers, government and academia. Presentations outlined the importance of innovation, which is closely alligned to the work carried out by Medical Technoloiges IKC. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Invited Talk to HYMS Medtech Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Jenny Southgate was invited to attend and give a talk at the HYMS Medtech Society meeting. |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | Invited talk at Biomaterials Symposium organised by Lancaster University (McCarthy POC068) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | Project outputs presented during an invited talk at Biomaterials Symposium organised by Lancaster University |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited talk at European Society for Paediatric Urology (Southgate - POC045) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Invited talk at the European Society for Paediatric Urology in Harrogate in 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited talk to John Hopkins University (Southgate - POC045) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Invited to talk at John Hopkins University |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited talk to Oxford University (Southgate - POC045) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Invited talk to Oxford University. |
| Year(s) Of Engagement Activity | 2018 |
| Description | JDH Talk at Leeds MedTech and Personalised Medicine - London Showcase |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr Jo Dixon-Hardy; Director - Medical Technology Innovation talk titled Connecting capability to support the commercialisation of tomorrow's MedTech products. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://leeds-medtech-and-personalised-medicine.eventcreate.com/ |
| Description | MEIbioeng15 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | The purpose of this workshop, held as part of the annual Medical Engineering Initiative (MEI) meeting, was to gather a diverse group of over 30 different stakeholders to discuss the opportunities and challenges of advancing knowledge and technology in the field of medical engineering and technology. Specifically, this MEI workshop chose to focus on the medical engineering landscape and the opportunities and challenges faced in the advancement of knowledge and technology and the translation of research. Over 30 people representing industry, the health service, regulators, investors, funders and academia participated in the workshop discussions. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Magazine article - Why get a filling when you could print a new smile? |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Online article in Horizon - The EU Research & Innovation Magazine |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://horizon-magazine.eu/article/why-get-filling-when-you-could-print-new-smile.html |
| Description | Manufacturing Technologies Association - UK Manufacturing Review Book Launch |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A published book containing an overview of the current centres of manufacturing within the UK (across all disciplines). |
| Year(s) Of Engagement Activity | 2015 |
| Description | MeDe Innovation Annual Conference 2017 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | the conference will report on progress and advances in research, innovation, and translation of its three focus areas: New approaches to manufacturing at the point of need Manufacturing regenerative devices, biological and biomimetic scaffolds Stratified design and manufacture of orthopaedic implants The conference will include presentations and posters from industry, regulators clinicians and academic researchers, panel discussions, poster pitches and networking opportunities. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://mede-innovation.ac.uk/event/mede-innovation-fourth-annual-conference/ |
| Description | MeDe Innovation Annual Review |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Glossy review of annual activity of the MeDe. Disseminate, share and discuss the impact of university-industry collaborations in the field of regenerative therapies and medical technologies. Includes case studies of MeDe projects, and funder metrics such as funding leveraged, numbers of people engaged, partners and collaborators. |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018 |
| Description | MeDe Innovation Conference (Newcastle) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | the conference will report on progress and advances in research, innovation, and translation of its three focus areas: New approaches to manufacturing at the point of need Manufacturing regenerative devices, biological and biomimetic scaffolds Stratified design and manufacture of orthopaedic implants The conference will include presentations and posters from industry, regulators clinicians and academic researchers, panel discussions, poster pitches and networking opportunities. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Med Tech Skills Academy Announcement |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Website article announcing the launch of the National MedTech Skills Academy, a partnership between educational institutions and medical technologies companies in the Leeds City Region. It will act as a centre of expertise with an industrial advisory group helping identify the key skills needed at all levels, from technicians to PhD design. The Academy consortium, including Leeds Beckett University and Bradford College, builds on a number of key existing strengths including the Leeds Academic Health Partnership and the Translate: Medical Technologies partnership |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://engineering.leeds.ac.uk/news/article/20034/faculty-of-engineering/436/leeds-to-establish-the... |
| Description | Medical Technologies IKC Annual Review |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Glossy review of annual activity of the MTIKC, launched to coincide with the annual IKC/Regener8 conference. Disseminate, share and discuss the impact of university-industry collaborations in the field of regenerative therapies and medical technologies. Includes case studies of POC projects, and funder metrics such as funding leveraged, numbers of people engaged, partners and collaborators. |
| Year(s) Of Engagement Activity | 2015,2016,2017,2018 |
| Description | Medical Technologies IKC and Versus Arthritis Virtual Conference 2020 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Hosted virtually on Zoom. We have teamed up with Versus Arthritis to give you a unique opportunity to hear the latest in medical technology development from both researchers and patients. The conference brings together a network of academics, industrialists, clinicians, patients and regulatory body representatives through lively presentations and interactive discussions. Sessions include: Updates from our most successfully translated projects Presentations from Versus Arthritis supporters and patients Interactive panel discussions |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://medical-technologies.co.uk/event/ikcconf2020/ |
| Description | Medical Technologies Science Fair - How to Engineer a Human - Leedc City College |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Exhibit and short talks at the Medical Technologies Open Day event at Leeds City College - in conjunction with numerous medical technology companies in the region to showcase what is going on in Leeds. Open to the general public and school/college students over the day - approximately 150 attendees in total. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://leeds.tech/event/how-to-engineer-a-human-2/ |
| Description | Medilink Healthcare Business 2016 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | This prestigious event celebrates excellence in the medical technology and healthcare sectors from across Yorkshire and the Humber. It gives local companies the opportunity to celebrate their ongoing commitment to world-class quality and excellence. The event is a showcase for the region and the diverse sector covering medical technologies, healthcare technology and related life sciences right across the region from Sheffield to Leeds to York and Hull. The Medical Technologies IKC presented the Skills Award. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Medipex Innovation Awards |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Medipex NHS Innovation Awards bring together the most innovative & exciting people from the region's NHS & commercial healthcare sector. Over 12 years, the event has established a reputation for showcasing outstanding projects and initiatives from across Yorkshire, Humber and East Midlands regions, providing a unique insight into up and coming new innovations and thinking from the NHS. We are delighted to be able to offer the opportunity for a small number of Companies to be involved. Sponsorship allows organisations be directly associated with the NHS innovation agenda and offers significant publicity opportunities. Attendance at the awards event also provides a unique opportunity to network with key NHS and healthcare business leaders. |
| Year(s) Of Engagement Activity | 2016,2017,2018 |
| Description | Mellanby Bone Imaging and Modelling Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Workshop held at Inox Conferencing Suite at University of Sheffield. Speakers on Bone Imaging for Fracture Prediction (Hip and Vertebral), Peripheral Imaging, Monitoring Treatment Effects on Bone. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://medicine.dept.shef.ac.uk/news/index.php/2017/04/19/mellanby-bone-imaging-and-modelling-works... |
| Description | Member of the Evaluation panel for CNR, Italy |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Consiglio Nazionale delle Ricerche (National Research Council) The evaluation panel was for scientific research proposal evaluation for Early Career Researchers. The research awards in Italy was €300K for 3 years. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Member of the Evaluation panel for FCT in Portugal |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Fundação para a Ciência e Tecnologia (Foundation for Science and Technology). The evaluation panel was for scientific research proposal evaluation for Early Career Researchers. The research awards in Portugal in €250K for three years. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Ministerial visit |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Article about Lord Pryor's visit to iMBE. Government Health Minister Lord Pryor met iMBE Director Professor Ruth Wilcox, heard an extensive presentation from Professor Paul Emery. He was shown the operation of the Leeds IKC and visited iMBE laboratory facilities to view the technical equipment used to produce world-leading research results. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Multiscale manufacture of biopolymer-based materials for healthcare. Ecole Polytechnique Department of Mechanics (France). |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | G. Tronci. Multiscale manufacture of biopolymer-based materials for healthcare. Ecole Polytechnique Department of Mechanics (France). Invited Seminar (online). 04.03.2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | National Centre for Universities and Business (NCUB) Case studies - DePuy |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The fourth annual report on the State of the Relationship between universities, business and policy makers, highlighting the partnership between the University of Leeds and DePuy Synthes. The annual report provides strong examples of university business partnerships with updated metrics on progress in collaboration between universities, business and government |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://medical-technologies.leeds.ac.uk/news-post/state-of-the-relationship-report-2017-highlights-l... |
| Description | Now is the time to invest in medical technologies sector |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Interview with Professor John Fisher, Director of the Institute for Medical and Biological Engineering, University of Leeds, about pioneering research in the fields of medical devices and regenerative medicine |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.opnews.com/2018/01/now-time-invest-medical-technologies-sector/14260 |
| Description | Orthopaedic Knee Conference 2016 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | This scientific meeting will aim to tackle current trends and topics as well as raise future surgical concepts and innovations. The one-day meeting will discuss topics including NJR / Beyond Compliance issues, Total knee arthroplasty and sessions on uni-knee replacement and soft tissue. It promises to be a highly stimulating event and a great educational resource for all delegates. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.opnews.com/programme |
| Description | Otley Science Fair 2018 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Exhibition at Otley Science Fair showcasing research undertaken around medical technology. Approx 600 members of general public engaged with stall - questions from many including patients and school children who may consider future career in engineering. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://otleysciencefestival.co.uk/festival/ |
| Description | Otley Science Festival 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Hands-on display presented at public science fair by researchers (PhDs and academics), sparked questions about role of engineering in healthcare. Developed understnading of best approaches to communicate to younger audience to take forwards for future activities. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://otleysciencefestival.co.uk/festival/ |
| Description | POC 71 (Miller) - 3 PPI meetings |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | The audience for these meetings were patient sand the general public with in interest in musculoskeletal research (and some oral and dental members for the Sheffield meeting). |
| Year(s) Of Engagement Activity | 2020 |
| Description | PPE Bradford |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | • To provide a technical focus for the polymer processing and technology industries • To discuss key developments in engineering excellence in polymer processing • To discuss recent developments in Advanced Materials in Healthcare and Medical Devices (focusing on MeDe Challenge 2, MeDe presentations are integral to this meeting) • To raise awareness of leading edge developments in polymer processing technology, in-process measurements and process flow modelling, and control |
| Year(s) Of Engagement Activity | 2015 |
| Description | PPI Webinars with Versus Arthritis |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | April - 20 Prepared and conducted four online webinars as part of PPI programme to engage with VA participants and patients living with arthritis (~30 - 50 People) |
| Year(s) Of Engagement Activity | 2020 |
| Description | PPI ask the researcher event |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | PPI group presentation on research, also lead to number of patients joining local patient user group |
| Year(s) Of Engagement Activity | 2019,2020 |
| Description | Patient Engagement Visit |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Visit by 35 members of the Patient and Public Involvement group at Chapel Allerton Hospital to the Institute of Medical and Biological Engineering at the University of Leeds. Day included short overview presentations from academics involved with musculoskeletal research (5 talks) and tours around the laboratories with demonstrations. Tours provided by PGR students, who had received training in engagement. Discussion afterwards highlighted interest of patients in our research and enabled a conversation to be held about the type of work IMBE does. Follow up visits themed around specific researc areas are planned for the future (e.g. knee programme grant focus). |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://leedsbrc.nihr.ac.uk/event/ask-researcher-institute-biomedical-engineering/ |
| Description | Patient USer Feedback Group 08/03/19 (POC057 Sammon Le Maitre SHU) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Patient engagement to understand clinical need, seek input and advice from patients on the need, application and use of the SNIPER technology to treat chronic back pain |
| Year(s) Of Engagement Activity | 2019 |
| Description | Patient group Workshop |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Patient User group meeting discussion of need for new therapies for low back pain and discussing current research plans |
| Year(s) Of Engagement Activity | 2019 |
| Description | Presentation at ERAS conference, Liverpool, June 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk by David Jayne titled 'Does new technology improve surgical outcomes?' |
| Year(s) Of Engagement Activity | 2019 |
| Description | Presentation at European Eye Bank Association Conference (Hanover, January 2020) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation titled 'A novel preservation technique for long-term storage and ambient distribution of transplantable human corneas' |
| Year(s) Of Engagement Activity | 2020 |
| Description | Presentation at Nottingham Eye Symposium (Nottingham, January 2020) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation titled 'A novel preservation technique for long-term storage and ambient distribution of transplantable human corneas' |
| Year(s) Of Engagement Activity | 2020 |
| Description | Presentation of Research Methods - NI Science Festival 2020 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | Research methods used during this project were presented to pupils visiting the university lab facilities (NI Science Festival 2020) |
| Year(s) Of Engagement Activity | 2020 |
| Description | Presentation of Research Methods - Soapbox Science 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Research methods used during this project were presented to the general public during SopabBox Science 2019 |
| Year(s) Of Engagement Activity | 2019 |
| Description | Presentation of Research Methods - Versus Arthritis |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Research methods used during this project were presented to volunteers working with Versus Arthritis |
| Year(s) Of Engagement Activity | 2019 |
| Description | Presentation pitch at Biotrinity Event |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Pitch presented at Bio trinity event April 2020 resulting in engagment with a number of potential industrial partners and manufacturing partners. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.obn.org.uk/Events-Calendar/283/biotrinity-2020-28-apr-2020 |
| Description | RSC Interest Group Porous Materials - Webinar |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | RSC Interest Group Porous Materials. 23rd June 2020. Online webinar. Title: Manufacturing Highly Porous Microspheres from Glasses, Glass Ceramics, Ceramics and Beyond |
| Year(s) Of Engagement Activity | 2020 |
| Description | Regen - Regener8 Annual Newsletter |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Glossy review of annual activity of the Regener8 programme. Review sponsored by the MTIKC |
| Year(s) Of Engagement Activity | 2014,2015,2016 |
| Description | Regener8 IKC Annual Conference - Call for community sourced session 20 Dec 2016 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | E-shot sent on 20 Dec 2016 to 1,083 unique subscribers to source community content for the IKC-Regener8 Conference 2017 |
| Year(s) Of Engagement Activity | 2016 |
| Description | Regener8-Medical Technologies IKC Annual Conference Sent on 26 May 2016 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | E-shot to promote the IKC-Regener8 conference 2016, showcasing the support and contributions the IKC team have made to projects. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Regenerative Devices Industry Partnership Call (Academic Target) Sent on 16 Sep 2016 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | E-shot sent on 16 Sep 2016 to academic unique subscribers to promote the IKC Industry POC. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Regenerative Devices Industry Partnership Call (Industry Target) Sent on 16 Sep 2016 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | E-shot sent on 16 Sep 2016 to industry unique subscribers to promote the IKC Industry POC. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Regulatory Affairs for Medical Devices |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Postgraduate students |
| Results and Impact | Translate: Me - workshop held on 16/01/2018. This workshop provides an introduction to the regulatory requirements for placing medical devices on the market. It will help participants to understand the regulatory pathway to CE marking a device. As well as guiding delegates through the Medical Device Directive, this workshop will also provide information about other relevant guidance, standards and the new Medical Device Regulations |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.translate-medtech.ac.uk/events/regulation-for-medtech/ |
| Description | Rehabilitation for Medical Technoloiges Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | This workshop provides an opportunity for clinicians and patients to engage with academics and companies to discuss new and novel ways to address unmet needs in the area of rehabilitation. We will define the challenges facing us, explore unmet clinical needs and patient priorities, form multidisciplinary teams to develop new interesting patient focused solutions and refine ideas into potential project opportunities that can be further supported and progressed in conjunction with the Translate team. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Research professional - ARUK POC announcement |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Continuing collaboration with ARUK (now Versus Arthritis) Opportunity profile: Getting medical devices to market - Proof of Concept Call: Researchers with solid ideas for medical devices for any musculoskeletal condition can apply for £100,000 and business coaching |
| Year(s) Of Engagement Activity | 2017 |
| Description | SMART Medical Devices Conference, Berlin |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | A unique knowledge-sharing platform around the best practices in discovery, development and innovation of medical devices technology. |
| Year(s) Of Engagement Activity | 2015 |
| Description | School Visit Engagement (McCarthy POC068) |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Research methods used during this project were presented to pupils visiting the university lab facilities |
| Year(s) Of Engagement Activity | 2018 |
| Description | School visit to deliver seminar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Education of sixth form children about strategies in regenerative medicine with a focus on regenerative devices |
| Year(s) Of Engagement Activity | 2017 |
| Description | Science Cafe Talk at Otley Science Cafe (Yorkshire) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Short talk at Otley Science Café based on biomechanics to 50+ members of the general public - ranging from 13 year old student to a group of 70yr +. Many questions following my talk, and contact from the University of the Third Age following the event to arrange a visit and a talk at the research institute. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Science Fair Stall - Otley Science Fair, Yorkshire |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Hands-on activities for children, parents and general public designed to highlight research undertaken within the Institute of Medical and Biological Engineering, and more broadly demonstrate what a bioengineer does. Good level of engagement with activities, many adults spent a long time at the stand discussing the research in more detail. Feedback captured by the Otley Science Fair team highlighted there was a lot of interest in our stand and it had highlighted a research area most were unaware of. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Science and Innovation Audit published - Medical Technologies in the Leeds City Region |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Science and Innovation Audit, commissioned by the Department of Business, Energy and Industrial Strategy (BEIS), highlighting investment opportunities for medical technologies. Led by Professor John Fisher from the University of Leeds, in partnership with the Leeds Enterprise Partnership (LEP), the region's universities and local businesses. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://medical-technologies.leeds.ac.uk/news-post/science-and-innovation-audit-published/ |
| Description | Science week 2019 school session |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | In School session during science week, sparked questions and discussion afterwards, raised awareness of research and stem cells. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Science week TED style talk |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Public presentation to wide audience, lots of interest from the audience and a clinician in the audience is interested in alternative uses for the hydrogel |
| Year(s) Of Engagement Activity | 2019 |
| Description | Sector deal recognition |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Website article highlighting how research into innovative medical technologies, spanning the Faculties of Engineering and Biological Sciences, has been recognised in the Government's Industrial Strategy Life Sciences Sector Deal. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://engineering.leeds.ac.uk/news/article/20034/faculty-of-engineering/428/government-recognition... |
| Description | Seminar at Sorbonne Universite' on 16.10.2020 (online) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The seminar aimed to provide an opportunity to identify topics of common interests; discussions are ongoing to identify areas of collaboration. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Seminar to the Equine Veterinary Medicine Centre (Qatar Foundation), Doha, Qatar, "Label free imaging of articular cartilage" 17 October 2018 (POC041 J Dudhia) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Seminar on label free imaging of articular cartilage |
| Year(s) Of Engagement Activity | 2018 |
| Description | Sheffield ARUk Hydrogels project |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Online article about work at Sheffield Hallam University - the development of a range of revolutionary hydrogels that may remedy degenerative disc disease |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www4.shu.ac.uk/mediacentre/scientists-test-potential-new-cure-back-pain?filter=Health |
| Description | Sheffield Teaching Hospitals NHS Foundation Trust's Oral and Dental PPI group |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | The PDRA (Caroline Harrison) presented the Dual Action Paste project to the Sheffield Teaching Hospitals NHS Foundation Trust's Oral and Dental PPI group. There was a question and answer session and the outcome was that the group would like to be engaged with the project in the future. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Speaking at NIPE Screening Programme Conference 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Public Health England - NIPE Screening Programme Conference 2019. Speaking in generalities |
| Year(s) Of Engagement Activity | 2019 |
| Description | State of the City Meeting - The Future of Manufacturing |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Medical technology - bringing together precision engineering with healthcare - is a field where Leeds has some world leading companies. We also have, in the University of Leeds, one of the country's leading research institutions in engineering and health. This workshop explores the possibilities that this sector brings, focussing on DePuy and Brandon Medical, two Leeds-based companies with global reputations, and on the University's research excellence. The speakers will describe the kind of work that is involved in medical technology innovation, and the sector's role in the future of the city. |
| Year(s) Of Engagement Activity | 2012,2015 |
| Description | TI World Conference Programme - Keynote |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Keynote presentation on textile medical devices and healthcare to the World Textile Institute Conference |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.tiworldconference.org/wp-content/uploads/2015/04/TIWC-2018-Programme-Final1.pdf |
| Description | TOKA website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Website to advertise, publicise and educate clinicians and the public about the new technology in development |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://www.toka.org.uk/ |
| Description | TV Interview for Clinical Researcher working on project (Southgate - POC045) |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Debora (the researcher on the POC project) has given a TV interview to journalist from That's TV York. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Termis - Americas |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Tronci G; Liang H; Wood DJ; Russell SJ (2017) Functionalised Collagen Systems With Bespoke Molecular And Macroscopic Characteristics For Chronic Wound Management 2017 TERMIS - Americas Conference & Exhibition, pp. S74-S74. Charlotte, NC |
| Year(s) Of Engagement Activity | 2017 |
| Description | The application of biopolymer-based hydrogels in healthcare. Soft Focus Day on Medical Applications of Soft Matter. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | G. Tronci. The application of biopolymer-based hydrogels in healthcare. Soft Focus Day on Medical Applications of Soft Matter. Invited Talk at EPSRC-funded CDT in Soft Matter and Functional Interfaces. 28.01.2022 |
| Year(s) Of Engagement Activity | 2022 |
| Description | Translate Digital Health Workshop with Regener8 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | This workshop was organised in partnership with Regener8 (The UK Regenerative Devices community) and DHEZ (the Digital Health Enterprise Zone), and was designed to identify and address unmet needs in the self-management and monitoring of long term health conditions. The workshop was professionally facilitated by Tim Morley from KnowInnovation. • To identify and discuss the current state of the sector, and identify high priority unmet needs. • To facilitate multi-institutional and multi-disciplinary collaboration between people working on or are interested in working on digital solutions for the self-management and monitoring of long term health conditions. • To develop and explore potential solutions to address the identified unmet needs. • To form collaborative multi-disciplinary teams interested in developing ideas into future project opportunities with support from the Translate team and input from Regener8. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Translate Rehabilitation for Medical Technologies Workshop |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | This particular workshop was hosted by Translate in partnership with Regener8 and Devices for Dignity Health Technology Cooperative (D4D HTC). It was designed to identify and address unmet needs in Rehabilitation through medical technologies. The workshop was professionally facilitated by Tim Morley from KnowInnovation. The specific aims of the workshop were: · To identify and discuss the current challenges within rehabilitation, and identify high priority unmet needs. · To facilitate multi-institutional and multi-disciplinary collaboration between people working on, or are interested in working on, medical technologies for rehabilitation. · To develop and explore potential solutions to address the identified unmet needs. · To form collaborative multi-disciplinary teams interested in developing ideas into future project opportunities with support from the Translate team and input from Regener8. |
| Year(s) Of Engagement Activity | 2016 |
| Description | UK MedEnterprise Training Network, Imperial College London |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Medical Technoloiges IKC attended the UK MedEnterprise Training Network workshop that aims to solidify and feed the medtech entrepreneurship ecosystem with networks will encompass everything from student training to full-scale medtech businesses. The workshop featured panel discussions, interactive sessions, and ample networking opportunities. One goal will be to provide exposure for the various university training programmes, and seek input from other constituents on programme content. There will also be featured elevator pitches from the emerging entrepreneurs that are an important output of these programmes. |
| Year(s) Of Engagement Activity | 2016 |
| Description | UKRMP Immunomodulation |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Key Focus To discover how to harness the immune system for improved outcomes in regenerative medicine. Aims and objectives: Our collective knowledge and shared experimental tools will be used to answer three key questions in regenerative medicine; 1. How do differentiated cells signal to the host innate and adaptive immune system? 2. How do transplanted cells provoke adaptive immune responses? 3. How does the inflammatory niche contribute to endogenous repair and influence the fate of transplanted cells? Key translational challenges to be addressed: The central goal of regenerative medicine is to replace damaged or diseased tissue. This can potentially be achieved by stimulating endogenous tissue repair or by transplanting autologous or allogeneic cells. No matter which strategy is taken, host immune responses can represent a formidable obstacle to success. Unless autologous cells are used, transplanted cells will have different degrees of major histocompatibility antigen (MHC) mismatch with the recipient and will thus be at risk of rejection by the adaptive immune system. Even when donor and recipient are matched for the MHC, antigen-independent inflammatory pathways (the innate immune system) modulate endogenous repair and can hinder donor cell engraftment. By modulating different aspects of the immune system we intend to improve the efficacy of regenerative medicine therapies. Expected outcomes: Our long-term clinical deliverables include: improved efficacy of photoreceptor cell therapy to treat blindness; improved repair of damaged heart tissue; and improved survival and functionality of transplanted hepatocytes as an alternative to liver transplantation. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Unmet needs workshop - Leeds |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Workshop identifying unmet needs - contribution lead to strategy development. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Versus Arthritis News article |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Profile of the VERDICT diagnostic tool for early detection of osteoporosis. |
| Year(s) Of Engagement Activity | 2017,2020 |
| URL | https://www.versusarthritis.org/news/2020/october/how-can-our-research-help-to-improve-the-diagnosis... |
| Description | Versus Arthritis News article |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Web page summarising the aims, importance, and patient benefits of the VERDICT diagnostic tool for early detection of osteoporosis. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.versusarthritis.org/research/our-current-research/our-current-research-projects/osteopor... |
| Description | Versus arthritis user group |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | patient user group meeting - discussed research areas and patient input, very engaged audience with lots of questions. |
| Year(s) Of Engagement Activity | 2020 |
| Description | West Yorkshire Economic Growth Conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | Exhibited Translate: at WYEGC. A day of discussion and opportunity for our region's business public sector leaders. Sponsorship included • Prime branding on the badges worn by all delegates • 3m2 Stand space (stand build additional) in the Exhibition area. • 5 Delegate passes for the conference. • Your logo will be displayed on the front page of the website. • Your logo will be on all documents related to the event - booking forms, emails etc. • One half page advert in conference programme. • Access to photographs and video of the event. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.built-environment-networking.com/event/west-yorkshire-development-event/ |
| Description | http://medical-technologies.leeds.ac.uk/news-post/heart-device-on-trial-that-could-save-the-nhs-200-million-a-year/ |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Article promoting a new cardiac scanning device that could save the NHS £200 million a year, being trialled at four of the UK's largest emergency departments (Bristol, Nottingham, Leicester and Sheffield). |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://medical-technologies.leeds.ac.uk/news-post/heart-device-on-trial-that-could-save-the-nhs-200-... |