New Enzymatically Produced Interpenetrating Starch-Cellulose Gels
Lead Research Organisation:
UNIVERSITY OF EXETER
Department Name: Engineering Computer Science and Maths
Abstract
The project aims to translate existing academic research to enable the production of interpenetrating network (IPN) gels of starch and nanocellulose fibres using side-by-side enzymatic and/or bacterial synthesis routes. These IPN gels will be produced with the end aim of use in the food and home care industries. The project will develop tandem enzymatic processes for the production of small fragments of starch, xyloglucan and cellulose, assembly of components into gels in the presence of water, and characterisation of the mechanical and physical properties of the gels. We will valorise waste, making new products, reducing costs and CO2 emissions for the companies we will support through this technology. Industrial input will guide development of the gels, targetting key industrial applications. No research has yet developed gels based on industrial biotechnology approaches to produce small molecules of starch combining them with cellulose fibrils.
Planned Impact
As described in proposal submitted to IUK
People |
ORCID iD |
| SJ Eichhorn (Principal Investigator) |
Publications
Bryant SJ
(2020)
Deep eutectic solvent in water pickering emulsions stabilised by cellulose nanofibrils.
in RSC advances
Calabrese V
(2020)
Core-Shell Spheroidal Hydrogels Produced via Charge-Driven Interfacial Complexation.
in ACS applied polymer materials
Calabrese V
(2020)
Charge-driven interfacial gelation of cellulose nanofibrils across the water/oil interface.
in Soft matter
Calabrese V
(2020)
Filler size effect in an attractive fibrillated network: a structural and rheological perspective
in Soft Matter
Calabrese V
(2019)
Understanding heat driven gelation of anionic cellulose nanofibrils: Combining saturation transfer difference (STD) NMR, small angle X-ray scattering (SAXS) and rheology.
in Journal of colloid and interface science
Calabrese V
(2018)
Surfactant controlled zwitterionic cellulose nanofibril dispersions.
in Soft matter
Courtenay JC
(2018)
Unravelling cationic cellulose nanofibril hydrogel structure: NMR spectroscopy and small angle neutron scattering analyses.
in Soft matter
Da Silva MA
(2018)
Alcohol induced gelation of TEMPO-oxidized cellulose nanofibril dispersions.
in Soft matter
Da Silva MA
(2020)
Impact of wormlike micelles on nano and macroscopic structure of TEMPO-oxidized cellulose nanofibril hydrogels.
in Soft matter
De Andrade P
(2021)
Chemoenzymatic Synthesis of Fluorinated Cellodextrins Identifies a New Allomorph for Cellulose-Like Materials*.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Engel E
(2020)
Composite Hydrogel Spheroids Based on Cellulose Nanofibrils and Nanofibrous Chiral Coordination Polymer by Green Synthesis
in Advanced Sustainable Systems
Hossain K
(2020)
Microstructural, Thermal, Crystallization, and Water Absorption Properties of Films Prepared from Never-Dried and Freeze-Dried Cellulose Nanocrystals
in Macromolecular Materials and Engineering
Hossain KMZ
(2020)
Cationic surfactants as a non-covalent linker for oxidised cellulose nanofibrils and starch-based hydrogels.
in Carbohydrate polymers
Johns MA
(2020)
Employing photoluminescence to rapidly follow aggregation and dispersion of cellulose nanofibrils.
in The Analyst
Koev TT
(2020)
Structural heterogeneities in starch hydrogels.
in Carbohydrate polymers
Nigmatullin R
(2019)
Thermosensitive supramolecular and colloidal hydrogels via self-assembly modulated by hydrophobized cellulose nanocrystals
in Cellulose
Nigmatullin R
(2020)
Hydrophobized cellulose nanocrystals enhance xanthan and locust bean gum network properties in gels and emulsions.
in Carbohydrate polymers
Nigmatullin R
(2018)
Mechanically Robust Gels Formed from Hydrophobized Cellulose Nanocrystals.
in ACS applied materials & interfaces
O'Neill EC
(2017)
Cellodextrin phosphorylase from Ruminiclostridium thermocellum: X-ray crystal structure and substrate specificity analysis.
in Carbohydrate research
Related Projects
| Project Reference | Relationship | Related To | Start | End | Award Value |
|---|---|---|---|---|---|
| EP/N03340X/1 | 31/05/2016 | 30/08/2017 | £797,598 | ||
| EP/N03340X/2 | Transfer | EP/N03340X/1 | 31/08/2017 | 07/03/2021 | £571,044 |
| Description | We have so-far shown that you can make cellulosic gels by enzymatic methods, and using cellulose nanofibrils and nanocrystals. The work is very preliminary and we are exploring the use of enzymes to reverse catalyse materials. The grant identified a number of potential applications and some of these are being pursued through other funding routes. |
| Exploitation Route | We have identified some potential products that could be commercially exploited. |
| Sectors | Agriculture Food and Drink Chemicals Healthcare Pharmaceuticals and Medical Biotechnology |
| Description | Understanding hydrophobic interactions in cellulose nanofibres |
| Amount | £24,040 (GBP) |
| Funding ID | EP/T005831/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2019 |
| End | 08/2024 |
| Description | MD starch |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Experimental evaluation of glycan structure and enzyme sensitivityt |
| Collaborator Contribution | Microsecond molecular dynamics simulation to assess glycan-glycan interactions |
| Impact | Too early |
| Start Year | 2017 |
| Description | Sugar nucleotides |
| Organisation | Keele University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Enzymatic synthsesis |
| Collaborator Contribution | Chemical synthesis - methods development and target synthesis. |
| Impact | New integrated chemical and enzymatic methods for sugar nucleotide synthesis |
| Start Year | 2020 |