A Holistic Framework for Hybrid Modelling of Solid-Liquid Flows
Lead Research Organisation:
University of Surrey
Department Name: Chemical Engineering
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
People |
ORCID iD |
| Chuan-Yu Wu (Principal Investigator) |
Publications
Hu J
(2021)
Numerical analysis of frictional charging and electrostatic interaction of particles
in AIChE Journal
Liu W
(2022)
Infiltration and resuspension of dilute particle suspensions in micro cavity flow
in Powder Technology
Liu W
(2020)
Modelling Complex Particle-Fluid Flow with a Discrete Element Method Coupled with Lattice Boltzmann Methods (DEM-LBM)
in ChemEngineering
Liu W
(2021)
Lateral migration of a neutrally buoyant particle in Couette flow with thermal convection
in International Journal of Multiphase Flow
Liu W
(2021)
Inertial migration of a neutrally buoyant circular particle in a planar Poiseuille flow with thermal fluids
in Physics of Fluids
Liu W
(2019)
Unified size-density and size-topology relations in random packings of dry adhesive polydisperse spheres.
in Physical review. E
Liu W
(2021)
Inertial migration of a non-neutrally buoyant particle in a linear shear flow with thermal convection
in Physical Review Fluids
Liu W
(2019)
Random loose packings of polydisperse adhesive microparticles with Gaussian size distribution
in Powder Technology
Liu W
(2020)
Migration and agglomeration of adhesive microparticle suspensions in a pressure-driven duct flow
in AIChE Journal
| Description | An accurate computational model is developed and thoroughly validated. Using the developed model, we discovered different flow regimes based upon a systematic numerical study. We have also explored systematically various liquid-solid flow behaviour including with the consideration of thermal effects, and discovered interesting liquid-solid flow behaviours and documented in our recent publications. |
| Exploitation Route | The model can be used by researchers working on liquid-solid flows. the developed regime map and the approach taken to construct the regime map can be of practical use to engineers and researchers. |
| Sectors | Chemicals Manufacturing including Industrial Biotechology |
| Description | Discrete element modelling (DEM) capabilities were significantly enhanced, which enables rigorous analysis of wet particle systems and robust simulations of full-scale twin screw granulators. The enhanced computational capabilities promote the up-take of this modelling technique in the pharmaceutical and food industry from which we have received direct industrial funding to explore the use of this technique in pharmaceutical manufacturing from Genentech and Janssen, as well as chocolate manufacturing from Mondelez. In addition, the enhanced computational capabilities also led to successful funding from EPSRC (e.g. EP/W027461) and EU H2020 (No. 813212) with a total budget over £5m. |
| First Year Of Impact | 2022 |
| Sector | Chemicals,Pharmaceuticals and Medical Biotechnology |
| Impact Types | Cultural Societal |
| Description | PDRA career development |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | DISPERSION AND DISSOLUTION OF HYDROCOLLOIDS |
| Amount | £749,741 (GBP) |
| Funding ID | EP/W027461/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2023 |
| End | 03/2026 |
| Description | MATHEGRAM - Multiscale Analysis of Thermomechanical Behaviour of Granular Materials |
| Amount | € 4,170,000 (EUR) |
| Funding ID | 813202 |
| Organisation | European Commission H2020 |
| Sector | Public |
| Country | Belgium |
| Start | 01/2019 |
| End | 12/2022 |
| Description | Mechanistic Multiscale Modelling of Drug Release from Immediate Release Tablets |
| Amount | £409,247 (GBP) |
| Funding ID | EP/X031969/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2024 |
| End | 07/2027 |
| Description | Migration of Pollutant Particles in Rivers: A Multiscale Approach |
| Amount | £99,000 (GBP) |
| Funding ID | 86203204 |
| Organisation | The Royal Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2018 |
| End | 12/2020 |
| Title | A new couped liquid-solid model |
| Description | A new numerical model based upon the coupling of Discrete Element Method and Lattice Boltzmann method has been developed. the 2D model has been validated and is currently being extended to 3D model |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2018 |
| Provided To Others? | No |
| Impact | the newly developed model enable solid-liquid systems to be modelled more accurately. |
| Title | New coupled DEM-LBM method |
| Description | On this project, we have now developed a new coupled numerical method and its accuracy was validated. |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2020 |
| Provided To Others? | No |
| Impact | A paper was submitted and hope to make the model available to others |
| Title | PREDICTING COHESIVE POWDER BEHAVIOURS BASED UPON INDIVIDUAL PARTICLE PROPERTIES : A DEM APPROACH |
| Description | This is a copy of my plenary lecture presented at the 10th international granulation workshop. In this lecture, I systematically outline the particle interactions that lead to powder cohesions, and how these interactions can be modelled at the particle level and how they are implemented in the discrete element method for modelling cohesive powder behaviour. I hope you will find it useful. Comments and suggestions are welcome. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2023 |
| Provided To Others? | Yes |
| Impact | This project significantly enhanced the capacity of the computer models and its robustness has been demonstrated in this dataset. |
| URL | https://zenodo.org/record/8404322 |
| Description | GENENTECH |
| Organisation | Genetech, Inc |
| Country | United States |
| Sector | Private |
| PI Contribution | Modelling capacity and expertise |
| Collaborator Contribution | Know-how and facility for pharmaceutical manufacturing |
| Impact | N/A |
| Start Year | 2019 |
| Description | GRAFFITI |
| Organisation | Johnson & Johnson |
| Department | Janssen Pharmaceutica NV |
| Country | Belgium |
| Sector | Private |
| PI Contribution | Utilising and adapting the models we are developing, we will explore the applications of these model in pharmaceutical manufacturing, in particular, in tablet film coating. |
| Collaborator Contribution | The partner will provide know-how on the practical manufacturing process, and running experimental campaigns to validate the model further. |
| Impact | no output as yet |
| Start Year | 2024 |
| Description | Jansson |
| Organisation | Johnson & Johnson |
| Department | Janssen Pharmaceutica NV |
| Country | Belgium |
| Sector | Private |
| PI Contribution | the computational model and know-how |
| Collaborator Contribution | know-how: pharmaceutical product development and manufacturing |
| Impact | Not yet, project only started a few months ago. |
| Start Year | 2020 |
| Title | 2D & 3D liquid-solid modelling software |
| Description | New 2D and 3D software coupling DEM with LBM was developed. |
| Type Of Technology | Software |
| Year Produced | 2020 |
| Impact | The new software will be able to analyse the two-phase flow of liquid-solid systems |
| Description | International conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | An invited talk at the international conference on computational methods, at which the recent developed in modelling complex particulate systems and liquid-solid systems were discussed. |
| Year(s) Of Engagement Activity | 2017 |
| Description | keynote/plenary lectures |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | We have been invited to given 3 plenary and keynote lectures to present the work on this grant |
| Year(s) Of Engagement Activity | 2020,2021,2022 |