Early-stage embryo as an active self-tuning soft material
Lead Research Organisation:
UNIVERSITY COLLEGE LONDON
Department Name: London Centre for Nanotechnology
Abstract
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Organisations
People |
ORCID iD |
| Guillaume Charras (Principal Investigator) |
| Description | In this project, we examine the role of mechanical feedback in guiding the organisation of the embryo. We devised new methods for characterising the mechanics of early chick embryos and for perturbing their mechanical environment. We showed that the primitive streak, an early structure eastblished in the embryo, appears stiffer than surrounding tissues. We also showed that application of tension to embryos precipitates a wave of cell ingressions. |
| Exploitation Route | N.A. |
| Sectors | Pharmaceuticals and Medical Biotechnology |
| Description | France 2030 |
| Geographic Reach | Europe |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Linking Signalling to Mechanics and Shape Changes in Mitotic Furrowing |
| Amount | £190,000 (GBP) |
| Funding ID | UKRI Horizon framework replacement funding |
| Organisation | Marie Sklodowska-Curie Actions |
| Sector | Charity/Non Profit |
| Country | Global |
| Start | 05/2023 |
| End | 06/2025 |
| Description | APS Physics journal |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | I responded to a media enquiry to comment about a new publication in a scientific journal. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://physics.aps.org/articles/v16/191 |