Metathesis Reactions as the Basis for Construction of Aromatic Compounds: Application to Both Methodology and Synthesis

Lead Research Organisation: University of Oxford
Department Name: Oxford Chemistry


Chemistry is a dynamic subject that is at the centre of many different scientific advances. Organic chemistry is concerned with the reactivity of carbon in all its different forms and can be viewed as the chemistry taking place within living things. Chemists are constantly looking for new ways of designing and building molecules (synthetic chemistry is molecular architecture) and this proposal describes a short and powerful new way of making valuable molecules using a new type of catalyst. The molecules at the heart of the proposal are aromatic compounds which have special properties and are the building blocks of most known pharmaceutical agents. Therefore, it is imperative that we have novel, efficient and powerful methods for making new aromatic compounds so that we can study and use them. In addition, the development of new catalysts is also important because it makes chemical reactions run faster, cleaner and with less waste: this is clearly a good thing for industry and also for the environment.


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Description New routes to aromatic compounds using catalysis based on ruthenium.
Exploitation Route Development of efficient routes to compounds of interest, especially those with bioactivity.
Sectors Pharmaceuticals and Medical Biotechnology

Description Development of efficient routes to compounds of interest; access to previously unobtainable compounds.
First Year Of Impact 2010
Sector Pharmaceuticals and Medical Biotechnology
Impact Types Economic

Description EPSRC
Amount £218,279 (GBP)
Funding ID EP/H051058/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 07/2011 
End 07/2013