Preparing MethodBox for National Service
Lead Research Organisation:
The University of Manchester
Department Name: Medical and Human Sciences
Abstract
This is a proposal to deliver a new on-line system for bringing different researchers together to share their expertise and work together on complex social problems. It is important to have different disciplines working together because individual disciplines have different strengths and weaknesses. For example a Social Scientist studying social factors in obesity may have excellent knowledge of how to measure socio-economic status whereas an Epidemiologist may have complementary knowledge about whether to use Body Mass Index or waist-to-hip ratio as the measure of obesity. Even within the Social Sciences there are different disciplines, for example those more familiar with qualitative than quantitative research methods, and vice versa - when a mixture of the two approaches would create a richer picture of the social problem being studied.
We are already working on this problem by using a combination of: 1) studying the way Social Scientists and Health Scientists use information for research; and 2) building web-browser based software to make it easier for researchers from different backgrounds to find the right data for their research question - supporting one another through social networks -like 'Facebook for Scientists'. The prototype of this system is called MethodBox and can be found at www.methodbox.org. Studies of the prototype have shown it is very popular with users from a wide range of backgrounds. By examining the way people use the system we can see that it could be developed further: moving from a simple system to help people find the data they are looking for to a more complex system that raises awareness of data and methods the researcher may not have considered. This awareness might be raised in new ways by harnessing the way researchers interact with datasets and with one another on-line. Like the shopping website Amazon, a user might be prompted "other researchers who selected your data items also selected these items...". This is particularly important with the growth in scientific knowledge because it is becoming less realistic for a researcher to have read all relevant papers before they start their research - for example last month over two thousand new papers were published on obesity.
With a sustained effort, beyond the funding period of the initial eScience Node project, MethodBox could be made ready for the national data services to use. This proposal seeks that sustainability funding so the Economic and Social Data Service and the UK Data Archive can have a reliable socially networked way that users can access archived data and share expertise. It is likely that MethodBox can release more research from the same level of investment in data services because users have a new facility for supporting one another. So investing in this project will multiply the large investments in data services. This proposal is directly in line with the "e-Infrastructure" changes that a recent report across the UK Research Councils called for.
We are already working on this problem by using a combination of: 1) studying the way Social Scientists and Health Scientists use information for research; and 2) building web-browser based software to make it easier for researchers from different backgrounds to find the right data for their research question - supporting one another through social networks -like 'Facebook for Scientists'. The prototype of this system is called MethodBox and can be found at www.methodbox.org. Studies of the prototype have shown it is very popular with users from a wide range of backgrounds. By examining the way people use the system we can see that it could be developed further: moving from a simple system to help people find the data they are looking for to a more complex system that raises awareness of data and methods the researcher may not have considered. This awareness might be raised in new ways by harnessing the way researchers interact with datasets and with one another on-line. Like the shopping website Amazon, a user might be prompted "other researchers who selected your data items also selected these items...". This is particularly important with the growth in scientific knowledge because it is becoming less realistic for a researcher to have read all relevant papers before they start their research - for example last month over two thousand new papers were published on obesity.
With a sustained effort, beyond the funding period of the initial eScience Node project, MethodBox could be made ready for the national data services to use. This proposal seeks that sustainability funding so the Economic and Social Data Service and the UK Data Archive can have a reliable socially networked way that users can access archived data and share expertise. It is likely that MethodBox can release more research from the same level of investment in data services because users have a new facility for supporting one another. So investing in this project will multiply the large investments in data services. This proposal is directly in line with the "e-Infrastructure" changes that a recent report across the UK Research Councils called for.
Planned Impact
Public sector professionals:-
We will enable public sector workers in the NHS and local authorities to collaborate in Social Science and use social research resources to support professional decision-making. For example, Public Health professionals having easy access to templates for extracting data from the Health Surveys for England (HSE) may avoid duplication of effort in local health surveys where population sizes are large enough to use HSE data instead - we have already identified such cases and avoided waste of public money. The ease of access will be provided via www.methodbox.org. We have already run training courses for Public Health professionals with MethodBox - the Public Health service is now asking for its early public release. Enabling the networking of datasets, expertise and methods for data preparation and analysis can help drive greater value from existing investments in survey data and research. We anticipate these improvements will translate into valuable Social Sciences and Public Health learning. In particular we see potential for wider use of secondary survey research in service needs assessments, impact assessments and policy option appraisals. Research undertaken within Obesity eLab eSocial Science Node identified both an interest in the use of secondary survey analysis in the public sector and an acknowledgement that many analysts felt they lacked the knowledge or skills to carry out such research. Further work led to new collaborations between Social Scientists and Public Health professionals over equity audit. In the Scale node we will build on the relationships forged in Obesity eLab to develop innovative resources for interdisciplinary collaboration - a step beyond sharing resources. This will positively impact local communities by bringing more relevant information to bear on the decisions made over local services, as well as benefiting the researchers concerned by increasing the impact of their work.
Society:-
The most recent ESRC Strategic Review, Delivery Plan and the ESRC National Centre for Research Methods' consultation in 2009 all identify the need for collaborative, interdisciplinary working for social impact. MethodBox will promote interdisciplinary working by making it easier for users from different disciplines to share their expertise over uses of common data services. This increased awareness and sharing is likely to improve the capability of research based to generate new insights into complex social problems such as obesity.
Users of data services:-
By working closely with ESDS/UKDA this project will bring a new scientific social networking interface to data services. The evidence of working with the MethodBox prototype in the current eScience Node indicates that this addition to data services will make it easier for inexperienced users to start using the services, and make it easier for experienced users to disseminate their expertise in ways that make them feel rewarded. MethodBox is therefore likely to increase the user-base and usability of data services.
Data service and project staff:-
The explicit transfer of eScience knowledge from this projects staff to ESDS staff will develop new informatics capability in the data services. Reciprocally, embedding the work in a data service in this way will seed future collaborations to harness generic innovations in eScience and shape them for social research.
We will enable public sector workers in the NHS and local authorities to collaborate in Social Science and use social research resources to support professional decision-making. For example, Public Health professionals having easy access to templates for extracting data from the Health Surveys for England (HSE) may avoid duplication of effort in local health surveys where population sizes are large enough to use HSE data instead - we have already identified such cases and avoided waste of public money. The ease of access will be provided via www.methodbox.org. We have already run training courses for Public Health professionals with MethodBox - the Public Health service is now asking for its early public release. Enabling the networking of datasets, expertise and methods for data preparation and analysis can help drive greater value from existing investments in survey data and research. We anticipate these improvements will translate into valuable Social Sciences and Public Health learning. In particular we see potential for wider use of secondary survey research in service needs assessments, impact assessments and policy option appraisals. Research undertaken within Obesity eLab eSocial Science Node identified both an interest in the use of secondary survey analysis in the public sector and an acknowledgement that many analysts felt they lacked the knowledge or skills to carry out such research. Further work led to new collaborations between Social Scientists and Public Health professionals over equity audit. In the Scale node we will build on the relationships forged in Obesity eLab to develop innovative resources for interdisciplinary collaboration - a step beyond sharing resources. This will positively impact local communities by bringing more relevant information to bear on the decisions made over local services, as well as benefiting the researchers concerned by increasing the impact of their work.
Society:-
The most recent ESRC Strategic Review, Delivery Plan and the ESRC National Centre for Research Methods' consultation in 2009 all identify the need for collaborative, interdisciplinary working for social impact. MethodBox will promote interdisciplinary working by making it easier for users from different disciplines to share their expertise over uses of common data services. This increased awareness and sharing is likely to improve the capability of research based to generate new insights into complex social problems such as obesity.
Users of data services:-
By working closely with ESDS/UKDA this project will bring a new scientific social networking interface to data services. The evidence of working with the MethodBox prototype in the current eScience Node indicates that this addition to data services will make it easier for inexperienced users to start using the services, and make it easier for experienced users to disseminate their expertise in ways that make them feel rewarded. MethodBox is therefore likely to increase the user-base and usability of data services.
Data service and project staff:-
The explicit transfer of eScience knowledge from this projects staff to ESDS staff will develop new informatics capability in the data services. Reciprocally, embedding the work in a data service in this way will seed future collaborations to harness generic innovations in eScience and shape them for social research.
Organisations
- The University of Manchester (Lead Research Organisation)
- Manchester City Council (Collaboration)
- British Broadcasting Corporation (BBC) (Collaboration)
- MANCHESTER UNIVERSITY NHS FOUNDATION TRUST (Collaboration)
- Manchester City Football Club (Collaboration)
- Nokia (Collaboration)
- Asda Stores Limited (Collaboration)
Publications

Ainsworth J
(2012)
eLab: bringing together people, data and methods to enhance knowledge discovery in healthcare settings.
in Studies in health technology and informatics

Ainsworth J
(2015)
Combining Health Data Uses to Ignite Health System Learning.
in Methods of information in medicine

Arnold M
(2015)
Global burden of cancer attributable to high body-mass index in 2012: a population-based study.
in The Lancet. Oncology

Arnold M
(2016)
Obesity and cancer: An update of the global impact.
in Cancer epidemiology

Badrick E
(2014)
Diabetes and cancer: 5 years into the recent controversy.
in European journal of cancer (Oxford, England : 1990)

Badrick E
(2017)
Obesity paradox and mortality in adults with and without incident type 2 diabetes: a matched population-level cohort study.
in BMJ open diabetes research & care

Badrick E
(2014)
Bias in the estimation of adult body mass index from general practice records
in European Journal of Public Health


Bechhofer S
(2013)
Why linked data is not enough for scientists
in Future Generation Computer Systems
Description | The findings which the funding for Methodbox provided delivered key information which has informed a key theme in the HeRC programme (CHIP-SET). Obesity and consistent use of BMI in reproducible research has continued to influence the designs of Trustworthy Research Environments now commonplace in clinical research, for example across the Department of Health and Social Care's Connected Health Cities Programme. |
Exploitation Route | The findings which the funding for Methodbox provided delivered key information which has informed a key theme in the HeRC programme (CHIP-SET). This is also formally disseminated across the UK by the Farr institute of Health Informatics (now Health Data Research UK). The basic Research Object and eLab concept originating in this research has been picked up and adopted not only in RCUK infrastructure such as STELAR and HeRC eLabs but also in NHS-linked eLabs such as the Connected Health Cities design and the Big Data 2 Knowledge initiative in the US. Children's Respiratory and Environmental Workgroup (CREW) This consortium proposes to identify specific types of childhood asthma, develop an understanding of what early life environmental influences cause these different types of asthma, and identify targets for future efforts aimed at preventing childhood asthma. To accomplish these goals, the scientific information and resources from 12 birth cohorts across the US will be combined, and investigators and biostatisticians will work collaboratively to analyze data that has already been collected along with new information to better understand the underlying causes of childhood asthma. |
Sectors | Digital/Communication/Information Technologies (including Software) Healthcare Pharmaceuticals and Medical Biotechnology |
URL | https://www.herc.ac.uk/2018/06/08/invisible-obesity-epidemic/ |
Description | The findings which the funding for Methodbox provided delivered key information which has informed a key theme in the MRC Health eResearch Centre www.herc.ac.uk and multiple lines of obesity and informatics research following from this work. The findings have been used in the designs of Trustworthy Research Environments in the public sector (e.g. Department of Health and Social Care's Connected Health Cities programme) and private sector (e.g. AIMES Ltd https://www.aimes.uk/p-health-cloud ) |
First Year Of Impact | 2016 |
Sector | Digital/Communication/Information Technologies (including Software),Healthcare,Government, Democracy and Justice,Pharmaceuticals and Medical Biotechnology |
Description | CRUK National Awareness and Early Diagnosis Initiative: Development of a risk prediction tool for early cancer detection in patients with type 2 diabetes |
Amount | £141,000 (GBP) |
Funding ID | 17962 |
Organisation | Cancer Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start |
Description | Diabetes UK Clinical Research Grant |
Amount | £218,495 (GBP) |
Funding ID | 14/0004971 |
Organisation | Diabetes UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2015 |
End | 12/2018 |
Description | MRC: STELAR |
Amount | £1,500,000 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 01/2013 |
End | 12/2017 |
Description | NIHR CLAHRC: Healthy children, healthy families: an applied public health research programme |
Amount | £1,000,000 (GBP) |
Organisation | National Institute for Health Research |
Department | NIHR CLAHRC Yorkshire and Humber |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start |
Description | The impact of body mass index on cancer-related survival in chemotherapy-naïve patients with non-metastatic colorectal and endometrial cancers: a federation meta-analysis of trial data |
Amount | £150,000 (GBP) |
Funding ID | 2016/1626 |
Organisation | World Cancer Research Fund |
Sector | Charity/Non Profit |
Country | Global |
Start | 02/2017 |
End | 01/2019 |
Title | Research Objects and Trustworthy Research Environments (eLabs) |
Description | Digital research laboratories with consitent orchestration of algorithms over challenging data sources in healthcare |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2016 |
Provided To Others? | Yes |
Impact | Continued to feed www.researchobject.org and spawned the Trustworthy Research Environment deployments across www.connectedhealthcities.org and wider NHS |
URL | https://www.herc.ac.uk/research_project/elab/ |
Description | Childhood Obesity Research Group for Innovation (CORGI) |
Organisation | Asda Stores Limited |
Country | United Kingdom |
Sector | Private |
PI Contribution | HeRC staff conducting a series of 'mini-workshops' with existing parent groups in primary schools in Manchester to inform the development of mobile health technology solutions to tackle childhood obesity. |
Collaborator Contribution | Direction and strategy |
Impact | Multidiscplinary team comprising of NHS; public health; academia; smes; greatersport et al - to address the obesity epidemic in children and adults using innovative technologies. Final outputs from the workshops will be used to inform future technology development. CORGI team are currently applying for further funding from British Heart Foundation to develop mobile technology for children's healthy weight management. |
Start Year | 2015 |
Description | Childhood Obesity Research Group for Innovation (CORGI) |
Organisation | British Broadcasting Corporation (BBC) |
Country | United Kingdom |
Sector | Public |
PI Contribution | HeRC staff conducting a series of 'mini-workshops' with existing parent groups in primary schools in Manchester to inform the development of mobile health technology solutions to tackle childhood obesity. |
Collaborator Contribution | Direction and strategy |
Impact | Multidiscplinary team comprising of NHS; public health; academia; smes; greatersport et al - to address the obesity epidemic in children and adults using innovative technologies. Final outputs from the workshops will be used to inform future technology development. CORGI team are currently applying for further funding from British Heart Foundation to develop mobile technology for children's healthy weight management. |
Start Year | 2015 |
Description | Childhood Obesity Research Group for Innovation (CORGI) |
Organisation | Manchester City Council |
Country | United Kingdom |
Sector | Public |
PI Contribution | HeRC staff conducting a series of 'mini-workshops' with existing parent groups in primary schools in Manchester to inform the development of mobile health technology solutions to tackle childhood obesity. |
Collaborator Contribution | Direction and strategy |
Impact | Multidiscplinary team comprising of NHS; public health; academia; smes; greatersport et al - to address the obesity epidemic in children and adults using innovative technologies. Final outputs from the workshops will be used to inform future technology development. CORGI team are currently applying for further funding from British Heart Foundation to develop mobile technology for children's healthy weight management. |
Start Year | 2015 |
Description | Childhood Obesity Research Group for Innovation (CORGI) |
Organisation | Manchester City Football Club |
Country | United Kingdom |
Sector | Private |
PI Contribution | HeRC staff conducting a series of 'mini-workshops' with existing parent groups in primary schools in Manchester to inform the development of mobile health technology solutions to tackle childhood obesity. |
Collaborator Contribution | Direction and strategy |
Impact | Multidiscplinary team comprising of NHS; public health; academia; smes; greatersport et al - to address the obesity epidemic in children and adults using innovative technologies. Final outputs from the workshops will be used to inform future technology development. CORGI team are currently applying for further funding from British Heart Foundation to develop mobile technology for children's healthy weight management. |
Start Year | 2015 |
Description | Childhood Obesity Research Group for Innovation (CORGI) |
Organisation | Manchester University NHS Foundation Trust |
Country | United Kingdom |
Sector | Public |
PI Contribution | HeRC staff conducting a series of 'mini-workshops' with existing parent groups in primary schools in Manchester to inform the development of mobile health technology solutions to tackle childhood obesity. |
Collaborator Contribution | Direction and strategy |
Impact | Multidiscplinary team comprising of NHS; public health; academia; smes; greatersport et al - to address the obesity epidemic in children and adults using innovative technologies. Final outputs from the workshops will be used to inform future technology development. CORGI team are currently applying for further funding from British Heart Foundation to develop mobile technology for children's healthy weight management. |
Start Year | 2015 |
Description | Large Scale Citizen Science Project for physical activity promotion |
Organisation | Nokia |
Department | Withings |
Country | France |
Sector | Private |
PI Contribution | As a result of the mature relationship developed between HeRC and Withings, a new project is being scoped and planned at present as a collaboration between Withings, The University of Manchester and ConnectedHhelath Cities. The aim is to conduct a citizen science project with mass participation across the North of England to understand how digital health can be used as an intervention to increase physical activity and lower heartrate. |
Collaborator Contribution | Withings bring expertise in the digital health and mobile health sector. Agreements are confidential as to scope of involvmenet at present. |
Impact | In progress |
Start Year | 2016 |
Description | Large Scale Citizen Science Project for physical activity promotion |
Organisation | Nokia |
Department | Withings |
Country | France |
Sector | Private |
PI Contribution | As a result of the mature relationship developed between HeRC and Withings, a new project is being scoped and planned at present as a collaboration between Withings, The University of Manchester and ConnectedHhelath Cities. The aim is to conduct a citizen science project with mass participation across the North of England to understand how digital health can be used as an intervention to increase physical activity and lower heartrate. |
Collaborator Contribution | Withings bring expertise in the digital health and mobile health sector. Agreements are confidential as to scope of involvmenet at present. |
Impact | In progress |
Start Year | 2016 |
Description | Withings Connected Health |
Organisation | Nokia |
Department | Withings |
Country | France |
Sector | Private |
PI Contribution | Analysis of data, preparation of manuscript for publication |
Collaborator Contribution | Provision of data, critical revision of manuscripts |
Impact | Paper: Sperrin, M., Rushton, H., Dixon, W., Normand, A., Villard, J., Chieh, A. & Buchan, I (2016). Who Self-Weighs and What Do They Gain From It? A Retrospective Comparison Between Smart Scale Users and the General Population in England. J Med Internet Res, 18(1), e17. eScholarID:296222 | PMID:26794900 | DOI:10.2196/jmir.4767 |
Start Year | 2014 |
Description | Demonstration of methodbox |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other academic audiences (collaborators, peers etc.) |
Results and Impact | Demonstration of Methodbox software at the Living Costs and Food Survey User Meeting organised by ESDS government Opportunity to present information about research project |
Year(s) Of Engagement Activity | 2012 |
Description | Methodbox |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other academic audiences (collaborators, peers etc.) |
Results and Impact | Demonstration of Methodbox software to delegates at the NCRM Research Methods Festival, Oxford Demonstration of Methodbox Software Demonstration of Methodbox Software |
Year(s) Of Engagement Activity | 2012 |
Description | Methodbox |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other academic audiences (collaborators, peers etc.) |
Results and Impact | Demonstration of the Methodbox Software at the Opinions and Lifestyle Survey User Meeting organised by the ESDS Government Opportunity to communicate aims of research project |
Year(s) Of Engagement Activity | 2012 |
Description | Methodbox : finding surveys and sharing methods |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other academic audiences (collaborators, peers etc.) |
Results and Impact | Presentation at the Family Resources Survey user meeting one day workshop organised by the ESDS government Opportunity to present information about the research project |
Year(s) Of Engagement Activity | 2012 |
Description | Methodbox : findings surveys and sharing methods |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other academic audiences (collaborators, peers etc.) |
Results and Impact | Presentation at the Using Large-Scale Government Microdata for Employment and Labour Market Research one day workshop organised by the ESDS Government Opportunity to present information about the research project |
Year(s) Of Engagement Activity | 2012 |
URL | http://ukdataservice.ac.uk/news-and-events/eventsitem/?id=3687 |
Description | www.methodbox.org |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other academic audiences (collaborators, peers etc.) |
Results and Impact | Poster presentation at the NCRM Research Methods Festival, Oxford to advertise Methodbox Poster to advertise Methodbox in the conference program |
Year(s) Of Engagement Activity | 2012 |
URL | http://www.methodbox.org |