Age Differences in the Implementation of Knowledge and Experience to Support Memory

Lead Research Organisation: University of Warwick
Department Name: Psychology

Abstract

Over the last century, improvements in standards of living and developments in medicine have resulted in more individuals reaching old age and life expectancy has risen significantly. This has led to older adults making up an increasing proportion of society and the current trend is likely to continue. Therefore, tackling issues related to ageing has become a major focus for medical practitioners, scientists, policy makers and economists.

Ageing not only results in a decline in physical abilities but also in cognitive abilities. The most widespread and salient age-related cognitive decline is a reduction in memory ability. In recent research in our laboratory, we have focussed on a factor that seems to alleviate age deficits in memory: When information that needs to be remembered is consistent with an individuals' knowledge and experience, it is easier to remember than abstract information and older adults appear to benefit from this effect more than do young adults. For example, when participants were asked to remember an association between two words, age differences in memory performance were smaller for related word pairs like article-book or fatigue-sleep compared to unrelated word pairs like article-lapel or fatigue-glass. This means that it may be possible to improve memory for all age groups, but particularly for older adults, by encouraging individuals to use knowledge and information that they are familiar with to support memory processes.

The proposed project aims to establish how knowledge and experience can support different memory processes. This will be achieved by investigating how people can use knowledge about the world to: 1. Distinguish between different information in memory during retrieval. 2. Improve the chances of thinking in the same way when encoding information and when retrieving information. 3. Reduce the amount of effort required to successfully encode and retrieve information.

Increasing our understanding of how knowledge and experience can support memory may lead to the development of new methods for alleviating age-related memory deficits. This would allow older adults with memory difficulties to retain independence for longer periods of time before requiring care. With the cost of full-time care reaching tens of thousands of pounds a year, extending independence even by just a few months will notably improve the financial circumstances for older individuals, their families and the state.

Planned Impact

The primary beneficiaries of this research will be academics working in the field of cognitive science. The main focus of the project is to highlight how pre-existing knowledge (familiarity) is used by individuals in memory tasks. The outcome will be to draw distinctions between the processing of familiar information and novel information. Processing of familiar and novel information occurs almost continuously in everyday life and therefore has widespread implications across many areas of psychology, neuroscience, gerontology and medicine. The key aim of the project is to provide foundation and guidance to future research by identifying fundamental aspects of cognition.

The most widespread impact of this research will be based on insights gained into methods for alleviating age deficits in memory. Through the research we will learn more about how pre-existing knowledge can reduce age deficits in memory. This information will be valuable to academics and medical practitioners seeking to extend the independence of older adults with declining mental health caused by dementia. For example, one possible implementation of pre-existing knowledge may be for older adults to establish a routine for their daily activities such as taking medication, maintaining hygiene, preparing meals, and so on. The established routine will be a pre-existing concept and may support memory for completing individual daily tasks. Even if such techniques only improve older adults' memory slightly, they may allow individuals to retain independence for an extra few months into the onset of dementia. This will have a large, positive financial impact on individuals and the state and should improve the happiness and quality of life for older adults for this extra period of time.

Publications

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Badham SP (2016) Antimnemonic effects of schemas in young and older adults. in Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition

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Badham SP (2016) When does prior knowledge disproportionately benefit older adults' memory? in Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition

 
Description The key focus of the grant was to investigate how knowledge and experience can alleviate the deficits in memory associated with old age. It has often been found that older adults can perform much better in memory tasks that involve existing knowledge. For example, when memorising pairs of words, older adults improve more than young adults when the words within each pair are related (e.g., flashlight-candle, harp-piano) compared to unrelated (e.g., flashlight-piano, harp-candle) and this reduces the general age deficits found in memory.
Our research indicates that this widely accepted pattern does not always occur. Thus, we have found several circumstances in which knowledge and experience help young and older adults similarly (i.e., the two age groups benefit equally from prior knowledge in memory tasks). These seem to be when the prior knowledge is based on frequency of encounter. That is, things that have been frequently experienced are generally more easily remembered than things that are novel or new for all age groups.
As highlighted above, words that are related are more memorable, especially for older adults. This may be because the relations form part of a unified concept (e.g, harp and piano are both musical instruments). In our research, we found no age differences in the benefit of knowledge and experience on memory tasks when that experience was based on frequency. For example both age groups similarly remembered 'a man sitting on a bench' better than 'a man sitting on a wall', with the former being more commonly encountered. However, with sentences such as 'The teacher marked the mock exam papers' and 'The teacher caught the train to London', the age deficit in memory was much smaller for the former. Older adults seemed to particularly benefit from the logical relation between the parts of the sentence ('the teacher' and 'marked the mock exam papers') because the action is one that is mainly linked to being a teacher. In the prior example of 'a man sitting on a bench', there are many more things that a man might do, even if sitting on a bench is more common than sitting on a wall.
Overall, we have established circumstances that determine whether knowledge/experience has an equivalent or greater benefit for older adults compared to young adults. We have found evidence that prior knowledge may help memory in two dissociable ways: (1) by enhancing the encoding/storage/retrieval of the episodic memory itself, which helps both age groups equally; and (2) by providing extra strategic/logical support in addition to the memory trace itself, which is disproportionately beneficial to older adults relative to young adults.
Exploitation Route The most immediate beneficiaries of this research will be academics working in the field of cognitive ageing (e.g., we already know of other labs that are following up our findings). Researchers are generally focussed on finding tasks that older adults can do well and tasks that older adults struggle with. This helps to classify cognitive processes that are spared or impaired, respectively, by cognitive ageing. Understanding age-related cognitive decline can benefit research in two ways. Firstly, it will allow researchers to pinpoint areas of the brain that are physiologically more susceptible to ageing (for example, by repeating the research in a neuroimaging study) and identify cognitive processes that are more susceptible to ageing. This will help to focus age-related palliative and preventative research on the most affected areas of age-related cognitive decline. Secondly, by highlighting processes that are most affected by ageing, the research may allow further insight into the most fragile cognitive processes. These fragile processes are likely to be the most complex or to be processes that require an ideal physiological environment in which to operate. This may also provide insight into understanding human behaviour and cognition in general (for example, processes less vital to survival may be more susceptible to failure).
Sectors Healthcare

 
Description In addition to academic journal articles arising from the grant (four already published, one in press, and three to be submitted shortly) and several international conference presentations, which have led to other labs following up our work, our findings have also been disseminated to members of the public via a talk to the University of the Third Age, with further such talks planned. The project led directly to a collaboration on a related grant proposal to ESRC, which received three "excellent" ratings though was not funded. We are continuing to use data from the project to explore new avenues of research with colleagues both at Warwick and elsewhere in the hope of establishing a clearer image of cognitive ageing and to investigate means of helping older adults function successfully in life with diminishing cognitive resources.
First Year Of Impact 2014
 
Title Ageing Data 
Description The database contains raw data for the publications resulting from this award. 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact Badham, S. P., Hay, M., Foxon, N., Kaur, K., & Maylor, E. A. (in press.). When does prior knowledge disproportionately benefit older adults' memory? Aging, Neuropsychology, and Cognition. Badham, S. P., & Maylor, E. A. (2016). Antimnemonic effects of schemas in young and older adults. Aging, Neuropsychology, and Cognition, 23, 78-102. Badham, S. P., & Maylor, E. A. (2015). What you know can influence what you are going to know (especially for older adults). Psychonomic Bulletin & Review, 22, 141-146. 
URL https://dx.doi.org/10.5255/UKDA-SN-852141
 
Description Aging and Memory as Discrimination: Influences of Encoding Specificity, Cue Overload, and Prior Knowledge 
Organisation Carnegie Mellon University
Department Department of Psychology
Country United States 
Sector Academic/University 
PI Contribution We have conducted research linking our ESRC grant to paradigms developed by Dr Marie Poirier with whom we have collaborated on a multi-experiment paper.
Collaborator Contribution The PI and CI have conducted and written up a study which is published in Psychology and Aging.
Impact An article published.
Start Year 2013
 
Description An Empirical and Computational Study of Category Learning in Normal Human Ageing 
Organisation University of Warwick
Department Department of Psychology
Country United Kingdom 
Sector Academic/University 
PI Contribution The PI and CI of this grant have collaborated with a specialist in categorisation (Dr Adam Sanborn) to submit an ESRC proposal (ES/N012542/1).
Collaborator Contribution The PI and CI worked on a large pilot study and production of the proposal itself.
Impact The proposal was unsuccessful. However, the pilot study was published in Psychology and Ageing.
Start Year 2014
 
Description 2013 Annual Meeting of the Psychonomic Society 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Presented research 'Word Frequency Does Not Influence Age-Related Associative Deficits, But Gender Does' to an international audience of academics. The poster presentation format allowed one-on-one discussion of research plans and hypotheses.

The research discussed influenced the understanding of age differences in the use of knowledge and experience in academics to whom it was presented.
Year(s) Of Engagement Activity 2013
URL http://www.psychonomic.org/past-future-meetings
 
Description 2014 Annual Meeting of the Psychonomic Society 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Presented research 'Age Invariance in the Mnemonic Effects of Knowledge-Based Schemas' to an international audience of academics. The poster presentation format allowed one-on-one discussion of research plans and hypotheses.

The research discussed influenced the understanding of age differences in the use of knowledge and experience in academics to whom it was presented.
Year(s) Of Engagement Activity 2014
URL http://www.psychonomic.org/past-future-meetings
 
Description Age Study Newsletter 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Participants in your research and patient groups
Results and Impact A newsletter was sent to around 450 older participants (aged 60 and over) who volunteer for research in the Department of Psychology at the University of Warwick. This was sent out to update participants about the research for which they volunteer and to check that they wanted to remain as volunteers. The newsletter helps participants feel engaged with the research and is a good opportunity to explain what has happened in studies to which they have contributed.

The newsletter contained a request for volunteers to ask friends and family if they want to also help with research at the University of Warwick. Around 30 replies were received each year and new volunteers were signed up to be contacted for research.
Year(s) Of Engagement Activity 2014,2015
 
Description Cognitive Aging Conference 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Research 'What You Know Can Influence What You Are Going to Know (Especially for Older Adults)' was presented to an international audience of academics. The poster presentation format allowed one-on-one discussion of research plans and hypotheses.

The research discussed influenced the understanding of age differences in the use of knowledge and experience in academics to whom it was presented.
Year(s) Of Engagement Activity 2014
URL http://cac.gatech.edu/content/program
 
Description Geneva Aging Series 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Research 'Age differences in the use of pre-existing knowledge to support memory' was presented to an international audience of academics. The presentation allowed group discussion of research plans and hypotheses.

The research discussed influenced the understanding of age differences in the use of knowledge and experience in academics to whom it was presented. The presentation led to inclusion of the principle investigator in a future ageing symposium.
Year(s) Of Engagement Activity 2014
URL http://www.unige.ch/fapse/aging/files/4014/1259/9585/Program_GAS3_2014.pdf
 
Description Holland House Ageing Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Research 'What you know can influence what you are going to know (especially for older adults)' was presented to an international audience of academics. The presentation allowed a group discussion of research plans and hypotheses.

The research discussed influenced the understanding of age differences in the use of knowledge and experience in academics to whom it was presented.
Year(s) Of Engagement Activity 2014
 
Description Third International Conference on Aging & Cognition 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Presented research 'Antimnemonic Effects of Schemas in Young and Older Adults' to an international audience of academics. The presentation resulted in questions and discussion by the audience.

The research discussed influenced the understanding of age differences in the use of knowledge and experience in academics to whom it was presented.
Year(s) Of Engagement Activity 2015
URL http://www.aging-cognition.de/