Biochemical security 2030 - towards improved science-based multilevel governance

Lead Research Organisation: University of Bath
Department Name: Politics, Languages and Int Studies

Abstract

It is increasingly clear that a major security concern in the area of low probability, high-impact events over coming decades will be that advances in life and associated sciences and technologies will enable the proliferation of chemical and biological weapons (CBW) to sub-state groups as well as to states. Furthermore, such weapons could be of novel types that the intended targets could not be easily defended against (Kelle, Nixdorff and Dando 2012). In response to these challenges the UK has played a leading role in enabling states parties to the Biological and Toxin Weapons Convention (BWC) and the Chemical Weapons Convention (CWC) to have specific measures available by which the chemical and biological prohibition regimes may be strengthened in order to reduce the threats form advances in science and technology (S&T) being misused for hostile purposes.

Starting at the multilateral level, the key objective of this project is to help improve the operation of those aspects of the BWC and CWC by focussing on advances in synthetic biology, neuroscience, and nanotechnology, including advanced drug delivery techniques. It will build on longstanding research carried out under funding for example from the Wellcome Trust and the Foreign and Commonwealth Office, and will address primarily two themes of the research grant specification for proposals:

- "Understanding how perceptions of S&T and its implications for defence and security vary across ... groups" [and]
- "Improving our ability to use S&T to increase co-operation and collaboration as a means of preventing future conflict."

Outputs from the project will feed directly - by means of briefing papers - to delegations in BWC meetings of experts and states parties in Geneva, and to experts and delegations in CWC meetings in The Hague, in 2013 and 2014. These papers plus additional relevant content will be made available to a wider audience on a dedicated project webpage. Analyses and findings of the briefing papers will be expanded upon in journal articles and a co-authored research monograph that will be submitted to a University press for publication.

The primary focus of attention in the project will be to investigate how the work of the BWC and CWC can be improved so that effective action can be taken to more efficiently develop awareness, education and any necessary codes of conduct and oversight systems for biologists, chemists and other associated scientists whose benignly intended work could be subject to misuse by those with malign intent. Such efforts are particularly relevant in parts of the world where regulation may presently be weak such as those identified by the G8 Global Partnership.

As many of the practical measures needed to achieve biochemical security are located at the domestic level, a second focus of the project will be on the establishment of a regional network of public and private research institutions and biotechnology companies active in the areas highlighted above that are located in the Southwest of the UK. The governance of biochemical security cannot rely exclusively on top down measures agreed upon at the international level, but needs to be complemented by efforts to involve those at the forefront at research in biology, chemistry and associated sciences, whose perceptions of S&T and its implications for defence and security can be expected to vary from those in government or academic security studies. This second strand of the project is thus focussing more on the theme of varying perceptions of the interrelation between science and security.

Biochemical security across the different levels of governance will take several years to realise. Assuming a concerted effort towards achieving this goal is undertaken soon, this project views the year 2030 as a realistic target for achieving biochemical security.

Planned Impact

As the key goal of the project is to contribute to an improved multilevel governance of biochemical security, the beneficiaries will include a variety of user groups ranging from the multilateral to the domestic UK governance level. The focus on different stakeholders across the different levels provides an excellent opportunity to connect these and thereby add real value. Possible non-academic beneficiaries include:
STATES PARTIES TO THE BIOLOGICAL AND TOXIN WEAPONS CONVENTION: States parties to the BWC gather regularly in Geneva to review operation of the treaty and to take into account S&T developments of relevance but lack either a scientific background to arrive at independent assessments, or the institutional back-up for the analysis of S&T advances, or both. At the 2011 BWC Review Conference S&T reviews have been made a so-called standing agenda item for the annual BWC meetings, but no improved infrastructure or processes have been put in place to facilitate the S&T review at the multilateral level.
STATES PARTIES TO THE CHEMICAL WEAPONS CONVENTION: States parties to the CWC have the comparative advantage that the organisation to oversee implementation of the treaty has a Scientific Advisory Board as subsidiary body. However, this board is responsible to the Director General of the organisation and its recommendations have been ignored by CWC states parties on several occasions.
Thus, states parties to both of these Convention stand to benefit from this project, albeit for different reasons. Yet, in both the CWC and the BWC contexts, the importance of S&T reviews has been long recognised, which can be expected to provide receptive audiences for the research results. This is further supported by the fact that the G8 Global Partnership countries, which are members in both treaty regimes have recently begun to focus on biosecurity as one area of primary concern
GOVERNMENT AUDIENCES: The UK national security community has identified biosecurity concerns triggered by biotechnological developments in recent threat assessments such as the MOD's Global Strategic Trends 2040. Likewise, the horizon scanning activities of the UK government have identified developments in synthetic biology, neuroscience and nanotechnology as S&T areas as having potentially great implications for defence and security. In addition, the Foreign and Commonwealth Office has identified the S&T dimension of the BWC inter-sessional process as a key area of interest in its counter-proliferation programme. The FCO will also be the lead department when the UK in 20013 will hold the chair of G8 Global Partnership, including its biosecurity element.
PROFESSIONAL ORGANISATIONS AND LEARNED SOCIETIES: The Royal Society has long shown an interest in the intersection of S&T and security issues. It has recently published the third module of its Brainwaves series in Conflict, Security and the Neurosciences. Learned societies and their members will benefit from this project due to its analysis of some of the practical measures that are being discussed in the CBW prohibition regimes, such as awareness raising and education and outreach on biological and chemical security to the S&T communities. An early awareness of these proposals will enable the scientific community to engage during the formulation of policy measures.
PUBLICLY AND PRIVATELY FUNDED RESEARCH INSTITUTIONS: Advances in the life sciences that could become a security concern are widely distributed across publicly and privately funded research institutions. As many of the governance measures discussed in the multilateral context will directly affect such research institutions, they will benefit from the awareness raising elements of this project.
THE GENERAL PUBLIC: This includes those members of the public with an interest in S&T, security issues, or both. Making project results available to the public will enable a wider discussion of S&T and security perceptions and opportunities for cooperation.
 
Description The Biochemical Security Project is a focused on examining and improving upon current capacities to identify and respond to scientific and Technological challenges which may undermine the existing bio-chemical non-proliferation regime. This regime incorporates international organisations, as well as national and local level capacities. At international level our project has produced a series of reports which have made recommendations directed at diplomats involved in the Biological and Chemical Weapons Conventions. These recommendations have focused on specific challenges which are driven by development in Science and technology. This includes for example security concerns raised by the field of synthetic biology as well as the continued development called 'less-than-lethal' weapon technologies, and weapon delivery systems which are relevant to the biological and chemical weapon conventions. In addition papers in our series have also assessed the current processes of Science and technology review within the two conventions.

In addition to this our project has brought together local, national and international policy makers and implementers to discuss means of making existing systems of security and safety governance more responsive to emerging and future security challenges. This was at a Meeting in May 2014.

At our most recent meeting we had a particular emphasis on examining how local level experience, can inform, and are informed by policy at national and international level. In particular this meeting focused on new means and forums to discuss and develop best practices in this issue area. A key focus was the potential role of local level networks to support and develop existing collaborations in this area. Many of the ideas raised at this meeting have informed further research into existing practices in a university context which are relevant to chemical and biological biosecurity within innovation. This includes for example, the role of university health and safety in laboratory safety and security as well as the role of university ethics bodies.

In 2014, our project also sponsored a panel at the International Studies Association Conference, which was held in Toronto.
Exploitation Route The team are collaborating with DSTL and academics in the UK and US for a further workshop to be sponsored by the Wellcome Trust on responsible biochemical innovation. The PI is Nicolas Evans at the University of Pennsylvania and CI is David Galbreath. All of the reports published by the project are open access and available at http://biochemsec2030.org.
Sectors Chemicals,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology,Security and Diplomacy

URL http://biochemsec2030.org
 
Description We have developed conceptual tools to understand the responsiveness of biological and chemocal weapons regimes to advances in science and technology; at international, national and local level. This has been achived through project embedded empirical research, which will result in a total of 12 policy papers. These papers have been actively distributed through mail, blog articles, news articles and meeting attendence. We are confident therefore, that these reports will inform policy over coming years. We have also organised three international conferences and facilitated two other events; Including a side event at the the UN Biological weapons convention and a policy event at the society of biology. Our project involved active engagement with practitioners and experts at our meetings; and through theses partnaerships we have developed a series of pratical reccomendations in our policy makers series. We have also acted as a facilitator of policy development through our international conferences. At our Novemeber 2014 meeting, for example, participants will be encouraged to feed back on an updated version of research council policy on dual-use research. Our website has also facilitated public discussion of chemical and biological weapon issues. Our page has had over 6,500 hits, we have recived comments via or comments section, and our twitter handle has over 200 followers. We have also already been invited to present on our findings at future biosafety and non-porliferation conferences; including the 2014 Biological Weapons Convetion Meeting of States parties.
First Year Of Impact 2013
Sector Chemicals,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology,Security and Diplomacy
Impact Types Policy & public services

 
Description Collaboration between Bath and the Unviersity of Sussex. 
Organisation University of Sussex
Country United Kingdom 
Sector Academic/University 
PI Contribution Sharing ideas, drafting, editing
Collaborator Contribution Sharing ideas, drafting, chairing meetings and presenting papers at confernces, editing
Impact Collaboration with the ESRC/Dstl funded project, University of Sussex . Sussex contributed to several of Bath meetings through chairing and presenting. There was also a joint publication of two articles by James Revill (Sussex) and Brett Edwards (Bath) on a) Synthetic biology and b) acid violence. The latter under revision after positive review. The former will be published as a policy paper in November.
Start Year 2013
 
Description Collaboration between Bath and the Unviersity of Sussex. 
Organisation University of Sussex
Country United Kingdom 
Sector Academic/University 
PI Contribution Sharing ideas, drafting, editing
Collaborator Contribution Sharing ideas, drafting, chairing meetings and presenting papers at confernces, editing
Impact Collaboration with the ESRC/Dstl funded project, University of Sussex . Sussex contributed to several of Bath meetings through chairing and presenting. There was also a joint publication of two articles by James Revill (Sussex) and Brett Edwards (Bath) on a) Synthetic biology and b) acid violence. The latter under revision after positive review. The former will be published as a policy paper in November.
Start Year 2013
 
Description 'Bio-chem, arms control and the frontiers of science and technology'- Presentation by Professor David Galbreath, at the University of Bristol, (November 2013). 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact -
Year(s) Of Engagement Activity 2013
URL http://biochemsec2030.org/policy-outputs/
 
Description 'Synthetic Biology and Biosecurity' Presentation by Brett Edwards . At SfAM winter meeting, at the Royal Society, London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Talk sparked discussion within the meeting about the security concerns related to synthethic biology.

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Year(s) Of Engagement Activity 2013
URL http://biochemsec2030.org/policy-outputs/
 
Description Biochemical Security 2030: Cutting Edge Advances in S&T and the Norm Against Biological and Chemical Weapons Presentation by Brett Edwards Defence Science and Technology Laboratory, Porton Down. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact My talk resulted in discussions among practioners about: Topics covered by our Policy paper series, the future of the field of Synthetic Biology, the regulation of select-agent pathogens, industry engagement with the oversight of biosecurity issues.

I had further requests for information, and several of the audience came to future project meetings.
Year(s) Of Engagement Activity 2014
URL http://biochemsec2030.org/policy-outputs/
 
Description Meeting on Regional Biochemical Security intiative 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact At out meeting we brought together experts from relevant government bodies and professionals involved in biosafety oversight in a university context. The aim of the meeting was to examine how new intiatives could be developed at regional (south-west) UK level to improve innovation biochemical security.

During the talk there were several key areas of agreement, and some provisional findings from this meeting included: the idea that innovation security policy is developed and implemented in quite different ways in different university contexts
a range of local, regional and national networks (both formal and personal) already exist which address which are relevant regional innovation security policy
there are a number of potential ways by which institutional innovation security policy could be more forward looking; for example it was suggested that there was need for greater security consultation when new laboratories were being designed and built
greater engagement with the scientific community, as well as education initiatives directed at this community would be of value to many of the stake-holders
that regional biochemical security networks could serve a number of potential roles and had support from many of those in attendance.
Year(s) Of Engagement Activity 2014
URL http://www.bath.ac.uk/polis/news/news_0077.html
 
Description Presentation by Ralf Trapp of apsects of his policy paper 'Convergence at the Intersection of Chemistry and Biology- Implications for the Regime Prohibiting Chemical and Biological Weapons'. At an event on Chem-Bio Convergence held at Spiez Labrorarory, 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact This event fed into policy discussions relevant to the implementation of the Chemical Weapons Convention.

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Year(s) Of Engagement Activity 2014
URL http://biochemsec2030.org/policy-outputs/
 
Description SIde event organised at the Meeting of States Parties, Biological Weapons Convetion 2013 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Provisional findings from our research as well as a report on our first project meeting were presented at an event which we organised by us at the UN Biological Weapons Convention Meeting of States Parties. This meeting took place at the annual meeting of the Biological Weapons Convention ( Meeting of States Parties). This meeting was attended by over 100 experts and diplomats
Meeting details below:
'Developments in science and technology (Room XXIV)
o University of Bath, Biochemical Security 2030 Project: Examining S&T responsiveness in the context of the BWC and CWC, report on current work
o OPCW Technical Secretariat on Chemical Weapons Disarmament in a Technologically Evolving World
o Croatian Academy of Science, US National Academies, Royal Society, International Union of Microbiological Societies on Science needs for Microbial Forensics:
Developing an International Science Roadmap
o Gerald Walther, University of Bradford on The 2013 BioWeapons Monitor:
Launch and Plans for the Future
o Dr Dana Perkins, UN 1540 Committee Expert, on UN Security Council Resolution 1540: Emerging Trends, Sharing of Experiences, Lessons Learned and Effective Practices?'
Reference was made to our meeting in the discussion among states parties that followed. In addition it was also picked up in the newsletter which is circulated daily to Diplomats at this event: http://www.cbw-events.org.uk/MSP13-02.pdf. Within the document, our thematic approach to organising the event was picked up on.

As a result of this successful meeting, The university of Bath was invited to present as an NGO at the BWC Meeting of Experts 2014.
Year(s) Of Engagement Activity 2013,2014
URL http://www.unog.ch/__80256ee600585943.nsf/%28httpPages%29/f837b6e7a401a21cc1257a150050cb2a?OpenDocum...
 
Description Smallpox, Bird-flu, Chicken-soup- Concerns About the Misuse of Medical Research 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact This talked sparked various questions from the audience about bioterror issues.

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Year(s) Of Engagement Activity 2013
URL http://biochemsec2030.org/policy-outputs/
 
Description Society of Biology Policy Lates meeting on the misuse of research. Chaired by Professor Malcolm Dando with a presentation from Catherine Jefferson on amateur biology. (July 2013). 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact This talk encouraged scientists and the public to consider the misuse potential of life science research.

This meeting resulted in several scientists thinking about this issue area for the first time. One of these scientists even produced a blog article about the meeting. This article was widely circulated via our project website, and was picked up by the scientists university, appearing on the university homepage. The blog article can be found here: http://biochemsec2030.org/2013/07/30/out-of-the-lab-and-into-the-ethics/.
Year(s) Of Engagement Activity 2013
URL http://biochemsec2030.org/2013/07/30/out-of-the-lab-and-into-the-ethics/
 
Description Statement by Dr Michael Crowley (University of Bradford) to the informal plenary session of the 18th Conference of States Parties to the Chemical Weapons Convention, The Hague, Netherlands, (5th December 2013). 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Talk, as well as associated paper was discussed on social media. This paper also appeared on project website. Following the release of the paper, our website experiences a significant rise in traffic.

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Year(s) Of Engagement Activity 2013
URL http://biochemsec2030.org/policy-outputs/
 
Description Statment given to the Meetin of Experts, Biological and Toxin Weapon Convention 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Further requests for information

Increased requests for further information.
Year(s) Of Engagement Activity 2014
URL https://biochemsec2030dotorg.files.wordpress.com/2013/08/bps-meeting-of-experts-2014.pdf
 
Description Technical Meeting on Verification: Hosted by VERTIC and CACDA 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation given, report produced. Report will provide the basis for future initiatives in this area.

Contiued Correspondence with UK delegation.
Year(s) Of Engagement Activity 2014