How can biomarkers and genetics improve our understanding of society and health?

Lead Research Organisation: University of Essex
Department Name: Inst for Social and Economic Research

Abstract

Understanding how people's social and economics lives relate to their health is essential to improving the nation's health, society in general and the economy.
Researchers in biomedical, social and economic sciences use robust, high quality data from world-leading studies to help develop this understanding. This research helps reveal hidden facts about the complex social and biological processes at work behind our everyday lives.

This proposal seeks to support this ambition to better understand people's lives and their health. It is based on Understanding Society - a rich social and economic study, which interviews the same families every year and has recently included a health interview where nurses took a number of 'biomarkers' or objective health measurements. These objective measures such as blood pressure, lung function and blood samples, have subsequently been analysed for indicators of heart disease, diabetes and anaemia, liver and kidney function and frailty. The project is led by a multi-disciplinary research team with international partners and has two broad aims:

* to contribute new scientific knowledge about the two-way relationship between people's social, economic, environmental circumstances and health;
* to build understandings of the value of and capacity for using biomarkers, genetic social and economic data together in collaborative projects.

The proposal will include a suite of exemplar research projects, which will not only address important research questions but demonstrate the value of inter-disciplinary [data and] research in these fields. It will investigate and use the best statistical techniques, and share learning with colleagues about these approaches. In addition, we will also:

*undertake a set of 'outreach' initiatives in specific social science disciplines - such as geography, economics and sociology - to investigate and disseminate the value of employing biomarkers to address social research questions relevant to them.
*establish a fellowship scheme for new researchers to propose projects at the interface of social and health sciences, which will be carried out with joint mentorship by social and biomedical scientists.
* hold a range of workshops and training events, and produce supporting resources, such as special datasets, to build understanding and capacity of the use of biomarkers in social science research.
* develop international collaborations to draw expertise from across the world into the project, and hold an annual master class and conference with contributions from them;
* involve policy makers in the oversight of the project, as well as set aside some funds for them to undertake analyses of the data relevant to their policy responsibilities. Policy relevant findings will be shared widely through briefings and a policy event.

This research will help to identify when and how health problems emerge in ways that enable policy makers to target policies more effectively. It will also help us understand how poor health affects people's ability to live their lives, which again may enable policy makers to identify appropriate times and situations when these negative consequences can be prevented or reduced. Such research directly contributes to the ESRC's strategic priority to influence behaviours and inform interventions. It will also improve the capacity of the research community to engage in this kind of research leading to future developments in this field.

Planned Impact

This project will include a wide range of individual exemplar projects that add to our understanding of how people's social and economic circumstances interact with their health at different life stages. Research findings will help us understand the social and economic processes that lead to ill health and provide better evidence about when inequalities in different dimensions of health arise. It will also shed light on the underlying biological processes, for example how spending time near green space or stress might 'get under the skin'. All of these findings will improve understandings of when to intervene and what sort of mechanisms to target to improve health. The project will also provide evidence of the effect of different aspects of ill health on people's social and economic lives, for example how ill health affects people's ability to extend their working lives or impacts on their need for social care.

The research will be relevant to a wide range of research users in government and third sector organisations that includes those with responsibility for employment (and in particular supporting people with health problems back to work), public health, health and social care, and the environment at national level. For example, within government, findings might be relevant to the Department for Work and Pensions, the Department for Environment Food & Rural Affairs and the Department of Health, Public Health England, the Scottish Government and Welsh Assembly. Think tanks and third sector agencies that would be beneficiaries of the research include medical charities such as Diabetes UK, campaigning organisations such as ASH , and organisations concerned with the needs of particular groups such as Age UK or the Child Poverty Action Group. Local agencies, in particular public health groups within local authorities and the NHS will also benefit from the evidence that emerges from this proposal. Independent research organisations that both synthesise and commission research, such as the King's Fund, Nuffield Foundation, Joseph Rowntree Foundation and Wellcome Trust, will be able to drawn on the findings produced here in their own policy related work.

A key focus of this proposal is to build capacity among social science researchers to undertake research that draws on biomarker and genetics data. The outreach and capacity building activities will benefit academics in a range of disciplines such as economics, geography, sociology, public health, demography, psychology, social policy, health services research, epidemiology, genetics and biomedical sciences. Through training events and the production of supporting resources, developing the skills and expertise of the staff and fellows employed on the study, networking and learning opportunities for senior staff engaged through the steering group or mentoring arrangements, this project will improve the skills and expertise of a wide range of researchers at different levels, building capacity for a much wider range of research projects to be conducted in the future. A particular emphasis has been placed in the project on international engagement by bringing leading international experts to the UK to contribute to the project, presenting at a wide range of international conferences and by developing collaborative projects to build networks and cross-country learning in these fields.

Finally, through the findings from the scientific research and learning from the networking opportunities that the project will provide, the UKHLS team will be in a better position to design subsequent rounds of data collection to advance scientific understandings at the interface of health and social research.

Publications

10 25 50
 
Description This was a wide ranging project that investigated the two way interaction between people's social economic and physical environments and their health. Specifically it used biological measures to measure health which enabled us to identify and understand pathways between environments and health more specifically. Research demonstrated strong associations between income, housing tenure, education, poor socioeconomic areas, pollution and health as measured by biomarkers that are linked to biological stress. We have also undertaken more specific research on employment and health which showed that women combining fulltime work and having children were more stressed than other woman and that work practices such as flexitime did not appear to reduce this higher stress; returning to employment after a period of unemployment led to better health only if the position had good job quality. . Another strand of research found that testosterone was associated with labour market success in men. Other research examined the ability of biomarkers to predict future disability and health care costs, finding it was a better predictor than self-report health data.
Exploitation Route This was a 3 year grant during which we undertook a programme of capacity building and engagement with other researchers and policy makers to develop understanding of the contribution of biomarkers to understanding social and biological processes leading to poor health. We have contributed analyses to a number of international consortium, which have published in leading journals such as Nature Genetics. We have mentor six fellowships based in a range of other universities to use the data and conduct biosocial research. hundreds of researchers have been to our training and other events. We have produced guides, podcasts, blogs, training videos and other materials that are on the Understanding Society website to continue to support the use of these data in the future.
Sectors Communities and Social Services/Policy,Environment,Healthcare,Transport

URL https://www.understandingsociety.ac.uk/
 
Description A number of research findings have already received widespread media interest for example on unemployment, under and over weight; income inequality and inflamation, and on the impact of returning to work on health, and of flexible work and health. Findings have been presented at POST and Gender and Equalities Office events, been featured in the Guardian, Observer and on BBC. A range of podcasts and blogs have been produced, as well as one research cartoon to create resources for public engagement with this research area. Evidence from one paper has been cited in the Taylor Review.
First Year Of Impact 2017
Sector Healthcare,Other
Impact Types Societal,Economic,Policy & public services

 
Description 19 July 2018 Invited paper "Equity, opportunity and health", 6th Health Econometrics Workshop, University of Bergamo.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 10 April 2018 Half-day workshop "Data visualization and health econometrics", Monash University Business School, Melbourne.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 11 July 2018 Preconference workshop "Data visualization and health econometrics", Conference of the European Health Economics Association, Maastricht.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 12 May 2018 Keynote address "Equity, opportunity and health", 100th Annual Conference of the Austrian Economics Association, Vienna.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 14 July 2018 Presidential Address "Empirical health economics", Conference of the European Health Economics Association, Maastricht.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 15-16 Nov 2018 Half-day workshop "Data visualization and health econometrics", University of Technology Sydney, Australia.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 15-16 Nov 2018 Seminar "Equity, opportunity and health", University of Technology Sydney, Australia.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 16 October 2017 Invited speaker on "Equality of Opportunity in Health" at Economics of Health Inequalities Workshop, Centre for Health Economics, Monash University, Melbourne.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 17 November 2017 Seminar presentation "Inequality of opportunity in health: a decomposition-based approach", Department of Quantitative Methods in Business and Economics, University of Gran Canaria in Las Palmas.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 22-23 Sept 2018 Two-day workshop "Data visualization and health econometrics", Technical University Berlin, Germany.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 23 Nov 2018 Half-day workshop "Data visualization and health econometrics", University of Adelaide, Australia.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 26 October 2017 Seminar presentation "Inequality of opportunity in health: a decomposition-based approach", Melbourne Institute, University of Melbourne.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 28 May 2018 Seminar "Equity, opportunity and health", Department of Economics, University of Utrecht.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 29 May 2018 Seminar "Equity, opportunity and health", Department of Economics, University of Leuven (KUL).
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 5 December 2017 Seminar presentation "Inequality of opportunity in health: a decomposition-based approach", University of Newcastle Business School.
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 5 June 2018 Seminar "Equity, opportunity and health", Health Economics Research Unit, University of Aberdeen.
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Andrew Jones: 7 Jan 2019 Half-day workshop "Data visualization and health econometrics", Health Economists' Study Group conference, York, United Kingdom.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Call for Understanding Society Biomarker Data Project Fellows
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
URL https://www.understandingsociety.ac.uk/2017/10/26/fellowships
 
Description Chaparro MP, Benzeval M, Richardson E, Mitchell R. Neighbourhood deprivation and biomarkers of health in the UK: the role of the physical environment. Short oral presentation, European Public Health Association (EUPHA) meeting. Vienna, Austria, November 9-12, 2016.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Chaparro MP, Hughes A, Kumari M, Benzeval M. The association between self-rated health and biomarker levels is modified by age, gender and household income. Oral presentation, Understanding Society Conference: Combining Biological and Social Data, London, UK, December 6, 2018.
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Generating policy impact from bio-social research (Raj Patel and Meena Kumari, Dec 2018)
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
Impact Developed the knowledge and skills of researchers in generating impact, with contributions from the Department for Work and Pensions, Age Uk and Public Health England.
 
Description NCRM training videos
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact Two 15 minute training videos hosted on utube by NCRM on how to use biomarker data
URL https://www.youtube.com/user/NCRMUK/videos?disable_polymer=1
 
Description Presentation - Biomarkers as precursors of disability. European Association of Health Economics, Maastricht 2018
Geographic Reach Europe 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Rebecca Richmond: Society of Social Medicine; Glasgow, UK, September 2018 (poster presentation: Investigating epigenetic changes in shift work - a possible mechanism for its impact on health and the body clock)
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Rebecca Richmond: Understanding Society Conference: Combining Biological and Social Data; London, UK December 2018 (oral presentation: Investigating epigenetic changes in shift work - a possible mechanism for its impact on health and the body clock)
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
 
Description SLLS Biomarker training course: scientific advisory committee
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description SS&M paper cited by a systematic review
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in systematic reviews
URL https://www.researchgate.net/profile/Almudena_Claassen/publication/326551325_A_Systematic_Review_of_...
 
Description Scottish Government consultation on obesity
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
URL https://cdn.ymaws.com/www.healtheconomics.org/resource/resmgr/EOSIG/EOSIG_response_to_Scottish_C.pdf
 
Description UK All Party Parliamentary Group
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
URL https://cdn.ymaws.com/www.healtheconomics.org/resource/resmgr/EOSIG/APPG_final.pdf
 
Description Centre for Doctoral Training
Amount £0 (GBP)
Organisation University of Essex 
Sector Academic/University
Country United Kingdom
Start 10/2016 
End 09/2023
 
Description ESRC - CLOSER Innovation Fund - Exploiting the existing biomarker data available in the CLOSER: age, social position and allostatic load
Amount £191,000 (GBP)
Funding ID EBB6900 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2015 
End 09/2017
 
Description ESRC enhancement funding - for 5 additional analytes
Amount £552,641 (GBP)
Funding ID ES/N00812X/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2017 
End 10/2021
 
Description ESRC enhancement funding - for Health Innovation Panel (IP12)
Amount £1,502,793 (GBP)
Funding ID ES/N00812X/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2017 
End 10/2021
 
Description ESRC enhancement funding - for consents interviews; review of cognitive scales; biomarker/ survey weights; NCMP linkage demo project; incentives
Amount £123,086 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2017 
End 10/2021
 
Description Major Research Fellowship (for Andrew Jones)
Amount £66,173 (GBP)
Organisation The Leverhulme Trust 
Sector Academic/University
Country United Kingdom
Start 09/2017 
End 08/2020
 
Description Social capital, health and wellbeing in ageing populations in the UK and Brazil
Amount £8,693 (GBP)
Funding ID ES/P010075/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 12/2016 
End 11/2017
 
Description Understanding Society: The UK Household Longitudinal Study: Waves 9-11 - enhancement funding - IP12 extension
Amount £330,925 (GBP)
Funding ID ES/N00812X/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2018 
End 10/2021
 
Description Understanding Society: The UK Household Longitudinal Study: Waves 9-11 - enhancement funding - epigenetics, proteomics, methodological fellows, event histories development work, public engagement activities, data infrastructure developments
Amount £1,729,626 (GBP)
Funding ID ES/N00812X/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2018 
End 10/2021
 
Title Understanding Society: The UK Household Longitudinal Study. Biomarker User Guide and Glossary 
Description This document contains an overview of the biomarker data available in Understanding Society. The glossary provides key information for each biomarker to help users with their analysis and provide relevant information to be considered when biomarker data are used for publications. For each biomarker the user guide and glossary outline: - the clinical significance of each biomarker, - a description of the role of the biomarker in the body; - laboratory methods and procedures used to measure the analyte; - guidance on factors to consider when analysing the biomarker; - distributions for each biomarker and where available, these distributions are compared to equivalent data available from the HSE or ELSA. 
Type Of Material Improvements to research infrastructure 
Year Produced 2014 
Provided To Others? Yes  
Impact This user guide and glossary has been cited by 19 research papers, helping researchers on how to construct biomarker research and make biomarker data easy to use even without prior experience in this field. 
URL https://www.understandingsociety.ac.uk/sites/default/files/downloads/legacy/7251-UnderstandingSociet...
 
Title Epigenetic Database with EGA and METADAC 
Description Epigenetic data processed on the Illumina EPIC array of 1175 samples from BHPS. 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact Applciations for the data via METADAC and numerous publications. 
URL https://www.understandingsociety.ac.uk/2017/04/03/new-epigenetics-data
 
Title Epigenetic Dataset Launched 
Description We have provided a methylation database of 1175 individuals from BHPS. DNA samples were run on the Illumina Infinium Methylation Epic Array, the most up-to-date-platform for this type of analysis 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact Increase in the number of applications for genetic and epigenetic data via the METADAC. 
URL https://www.understandingsociety.ac.uk/events/2017/04/27/understanding-society-epigenetics-data-laun...
 
Title Genetics and epigenetics datasets - combined genotype phenotype data 
Description Set of genetics or and/or epigenetics datasets provided to different groups of researchers, via Metadac. To March 2018, 20 datasets have been supplied with a further 4 in progress. 
Type Of Material Database/Collection of data 
Year Produced 2016 
Provided To Others? Yes  
Impact Further research combining genetics/ epigenetics data and UKHLS data. 
 
Title MDAC_2017_0016_02_mills 
Description Provided a genetic dataset to University of Oxford 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact Potential publication 
 
Title MDAC_2017_0017_02_jerrim 
Description Provided a genetic and epigenetic dataset to UCL 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact pOtential publication 
 
Title MDAC_2017_0023_02_barrett 
Description Provided a genetic dataset to WTS 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact Potential publication 
 
Title MDAC_2017_0024_02_kippersluis 
Description Provided a genetic dataset to Rotterdam University 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact Potential publication 
 
Title MDAC_2017_0031_02_mills 
Description Provided a genetic dataset to University of Oxford 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Potential publication 
 
Title MDAC_2017_14_02_kuchenbaceker 
Description Provided a genetic and epigenetic dataset for UCL 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact Potential publication 
 
Title MDAC_2018_0002_02A_diangelantonio 
Description Provided a genetic and epigenetic dataset to University of Cambridge 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Potential publication 
 
Title MDAC_2018_0004_02E_corbyn 
Description Provided a genetic dataset to University of Bristol 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Potential publication 
 
Title MDAC_2018_0008_02E_green 
Description Provided a genetic dataset to Univeristy of Liverpool 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Potential publication 
 
Title MDAC_2018_0016_02E_belsky 
Description Provided a genetic and epigenetic dataset 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Potential publication 
 
Title MDAC_2018_0016_02E_relton 
Description Provided a genetic and epigenetic dataset to University of Bristol 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Potential publication 
 
Title MDAC_2018_0031_02a_frayling 
Description Provided a genetic dataset to University of Oxford and Exeter 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Potential publication 
 
Title MEATDAC application: MDAC-2017-0016-02-Mills 
Description UKHLS genetics data provided to University of Oxford for project: Genes, cognitive function, political behaviours and orientations 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Further use of UKHLS genetics data - scientific impact 
 
Title METADAC Application - MDAC_2017_0004_02 
Description Provided a dataset to University of Oxford to research matching models, schooling, marriage, exclusion restiction, IV and polygeneic scores. 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact N/A 
 
Title METADAC Application - MDAC_2017_0009_02_Richmond 
Description Provided a genetic and epigenetic database to University of Bristol to research the imapct of shiftwork on DNA methylation. 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact N/A 
 
Title METADAC Application - MDAC_2017_0011_02_Yousefi 
Description Provided a genetic and epigenetic database to the University of Bristol to research the impact of economic conditions at year of birth on DNA methylation age acceleration. 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact N/A 
 
Title METADAC Application - MDAC_2017_13_02_Lewis_Zebaneh 
Description Provided a genetic and epigenetic dataset to UCL to investigate the genetic relationship between anxiety, depression on CVD risk factors and disease. 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact N/A 
 
Title METADAC Application - USOCDAC 030 
Description Created a dataset combining genetic data with main survey data for UCL, project on using genetic markers to understand CV risk factors, mental, cognition and well-being. Dataset released to applicant February 2016 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact N/A 
 
Title METADAC Application - USOCDAC 031 
Description Created a dataset combining genetic data with main survey data for University of Bristol - CARTA Consortium Dataset released to applicant February 2016 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact N/A 
 
Title METADAC Application - USOCDAC 032 
Description Created a dataset combining genetic data with main survey data for University of Bristol, project on MR: causal role of Insulin-like growth factors in prostate cancer. Dataset released to applicant February 2016 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact N/A 
 
Title METADAC Application - USOCDAC 033 
Description Created a dataset combining genetic data with main survey data for Nuffield, Oxford, project REPROGENE - Genome Wide Gene-environment Interactions for Reproductive Behaviour. Dataset released to applicant February 2016 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact Potential journal article 
 
Title METADAC Application - USOCDAC 036 
Description Created a dataset combining genetic data with main survey data for University of East Anglia, project on assortative mating. Dataset released to applicant February 2016 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact Journal article published 
URL http://dx.doi.org/10.1016/j.intell.2016.08.005
 
Title METADAC Application: 2015_UKHLS_04 
Description Created a dataset combining genetic data with main survey data for Wellcome Trust Sanger, project on FPLD1 and severe insulin resistance GWAS Dataset released to applicant February 2016 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact Journal article published 
URL http://www.nature.com/ng/journal/v49/n1/full/ng.3714.html
 
Title METADAC Application: 2016_UKHLS_01_NICODEMUS 
Description Created a dataset combining genetic data with main survey data for University of Edinburgh, project on genomics of social support, personality and cognition. Dataset released to applicant July 2016 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact Potential journal artcile 
 
Title METADAC Application: 2016_UKHLS_03_CARVALHO 
Description Created a dataset combining genetic data with main survey data forQueen Mary University, project on Inflammatory cytokines IL-6, IL-1 and CRP as causal risk factors for depressive symptoms: MR Study Dataset released to applicant September 2016 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact N/A 
 
Title METADAC Application: MDAC-2017-0006-02 
Description Provided data to the University of Edinburgh to perform a meta-analysis of genome-wide association studies of general cognitive function in the CHARGE and COGENT consortia. 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact N/A 
 
Title METADAC application - 2017-12 and 14 - 02-Kuchenbaecker 
Description Provided genetics and epigenetics data to UCL for projects: An assessment of the genetic architecture of mental health indicators; Effects of GxE intercations on biomarker levels. 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact Further use of UKHLS genetics and epigenetics data - scientific impact of research 
 
Title METADAC application: MDAC-2017-0017-02-Jerrim 
Description Genetics data provided to UCL for project: Educational attainment and socio-economic gaps 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact Further research using UKHLS genetics data - scientific impact 
 
Title METADAC application: MDAC-2017-0023-02-Barrett 
Description Use of UKHLS genetics data in project: Understanding the genetics of neurodevelopmental disorders 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact Further use of UKHLS genetics data - scientific impact 
 
Title METADAC application: MDAC-2017-0024-02-van Kippersluis 
Description Use of UKHLS genetics data for project: Gene-Environment Interplay in the Generation of Health and Education Inequalities 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Further use of UKHLS genetics data - scientific impact 
 
Description DTRN: Data training and resource network 
Organisation UK Data Service
Country United Kingdom 
Sector Academic/University 
PI Contribution This network was established to promote the use of ESRC data infrastucture and to support its use by providing training and resources. We have contributed a range of resources about Understanding Society and contributed to training events and documents.
Collaborator Contribution as above
Impact range of training events held
Start Year 2014
 
Description DTRN: Data training and resource network 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution This network was established to promote the use of ESRC data infrastucture and to support its use by providing training and resources. We have contributed a range of resources about Understanding Society and contributed to training events and documents.
Collaborator Contribution as above
Impact range of training events held
Start Year 2014
 
Description DTRN: Data training and resource network 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution This network was established to promote the use of ESRC data infrastucture and to support its use by providing training and resources. We have contributed a range of resources about Understanding Society and contributed to training events and documents.
Collaborator Contribution as above
Impact range of training events held
Start Year 2014
 
Description DTRN: Data training and resource network 
Organisation University of Southampton
Department Administrative Data Research Centre for England
Country United Kingdom 
Sector Academic/University 
PI Contribution This network was established to promote the use of ESRC data infrastucture and to support its use by providing training and resources. We have contributed a range of resources about Understanding Society and contributed to training events and documents.
Collaborator Contribution as above
Impact range of training events held
Start Year 2014
 
Description DTRN: Data training and resource network 
Organisation University of Southampton
Department ESRC National Centre for Research Methods
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution This network was established to promote the use of ESRC data infrastucture and to support its use by providing training and resources. We have contributed a range of resources about Understanding Society and contributed to training events and documents.
Collaborator Contribution as above
Impact range of training events held
Start Year 2014
 
Description Does Education Modify the Genetic Risk of Obesity? 
Organisation University of Michigan
Country United States 
Sector Academic/University 
PI Contribution Analysis submitted from the genetic and main survey data.
Collaborator Contribution Provided analysis plan
Impact One paper published in Social Science and Medicine (http://dx.doi.org/10.1016/j.socscimed.2017.10.027). Second paper underway.
Start Year 2016
 
Description Effects of personal traits and life style on wellbeing 
Organisation University of Kent
Country United Kingdom 
Sector Academic/University 
PI Contribution We generated Polygenetic risk score using genetic data and contributed to analysis.
Collaborator Contribution Analysis personal traits and life style on wellbeing using Polygenetic risk score as instruments and write the manuscript.
Impact Preparing and analysing data.
Start Year 2018
 
Description GWAS of Human Reproductive Behaviour 
Organisation University of Oxford
Department Department of Sociology
Country United Kingdom 
Sector Academic/University 
PI Contribution Analysis submitted from the genetic and main survey data.
Collaborator Contribution Provided analysis plan for all involved. Wrote the manuscript to be submitted.
Impact Final draft of manuscript in circulation
Start Year 2017
 
Description GWAS of kidney function (eGFR) 
Organisation University of Copenhagen
Department Faculty of Health and Medical Sciences
Country Denmark 
Sector Academic/University 
PI Contribution Analysis submitted from the genetic and main survey data.
Collaborator Contribution Provided analysis plan for all involved. Wrote the manuscript to be submitted.
Impact Journal article written and ready for submission.
Start Year 2017
 
Description GWAS on subjective well-being 
Organisation Free University of Amsterdam
Department Department of Biological Psychology
PI Contribution We have provided analysis from the genetic and main survey data from Understanding Society.
Collaborator Contribution Provided analysis plan for all involved. Wrote the manuscript to be submitted.
Impact Paper published in Nature Genetics
Start Year 2017
 
Description International partner: biomarkers and genetics 
Organisation National Institute of Health and Medical Research (INSERM)
Country France 
Sector Public 
PI Contribution Collaboration to exploit and promote biomarker data in Understanding Society, organised masterclass, hosted visit, advising on use of data
Collaborator Contribution Run masterclass, participated in steering group, developing further collaborations
Impact Masterclass event
Start Year 2015
 
Description International partner: biomarkers and genetics 
Organisation University of California, Los Angeles (UCLA)
Department School of Medicine UCLA
Country United States 
Sector Academic/University 
PI Contribution Organise masterclass and range of other training and engagment activities, develop collaborative projects
Collaborator Contribution lead masterclass, contribute to other activites and steering group, develop collaboartions
Impact none yet.
Start Year 2015
 
Description International partner: biomarkers and genetics 
Organisation University of Southern California
Country United States 
Sector Academic/University 
PI Contribution Will host masterclass and range of other engagemetn activities, develop collaborative projects
Collaborator Contribution Will lead masterclass, contribute to steering group and take part in range of other engagement activities to promote use of genetics in social science research.
Impact none yet
Start Year 2015
 
Description SSGAC GWAS on risk preferences 
Organisation Social Science Genetics Association Consortium
Country Global 
Sector Charity/Non Profit 
PI Contribution We have provided analysis from the genetic and main survey data from Understanding Society.
Collaborator Contribution The SSGAC is a cooperative enterprise among medical researchers and social scientists that coordinates genetic association studies for social science outcomes and provides a platform for interdisciplinary collaboration and cross-fertilization of ideas. The SSGAC also tries to promote the collection of harmonized and well-measured phenotypes.
Impact Paper publised in Nature Genetics
Start Year 2015
 
Description Understanding Society - Wellcome Trust Sanger Institute - collaboration on genetics data and analysis 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Collaborative work to share the genetics data from Understanding Society and use it for analysis.
Collaborator Contribution As above.
Impact See other outputs for: ES/H029745/1 and ES/M008592/1
Start Year 2012
 
Description Understanding Society Biomarker Fellowships 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution 6 Fellowships offered by Understanding Society
Collaborator Contribution Research Projects using Understanding Society data, in collaboration with expert team members.
Impact Research projects have just commenced - publications and events are planned for later in 2018 when the projects are further developed. Each of the Fellows will present their research at international conferences, raising awareness of UKHLS data and its use.
Start Year 2018
 
Description Understanding Society Biomarker Fellowships 
Organisation London School of Economics and Political Science (University of London)
Country United Kingdom 
Sector Academic/University 
PI Contribution 6 Fellowships offered by Understanding Society
Collaborator Contribution Research Projects using Understanding Society data, in collaboration with expert team members.
Impact Research projects have just commenced - publications and events are planned for later in 2018 when the projects are further developed. Each of the Fellows will present their research at international conferences, raising awareness of UKHLS data and its use.
Start Year 2018
 
Description Understanding Society Biomarker Fellowships 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution 6 Fellowships offered by Understanding Society
Collaborator Contribution Research Projects using Understanding Society data, in collaboration with expert team members.
Impact Research projects have just commenced - publications and events are planned for later in 2018 when the projects are further developed. Each of the Fellows will present their research at international conferences, raising awareness of UKHLS data and its use.
Start Year 2018
 
Description Understanding Society Biomarker Fellowships 
Organisation University of Exeter
Country United Kingdom 
Sector Academic/University 
PI Contribution 6 Fellowships offered by Understanding Society
Collaborator Contribution Research Projects using Understanding Society data, in collaboration with expert team members.
Impact Research projects have just commenced - publications and events are planned for later in 2018 when the projects are further developed. Each of the Fellows will present their research at international conferences, raising awareness of UKHLS data and its use.
Start Year 2018
 
Description Understanding Society Biomarker Fellowships 
Organisation University of Liverpool
Country United Kingdom 
Sector Academic/University 
PI Contribution 6 Fellowships offered by Understanding Society
Collaborator Contribution Research Projects using Understanding Society data, in collaboration with expert team members.
Impact Research projects have just commenced - publications and events are planned for later in 2018 when the projects are further developed. Each of the Fellows will present their research at international conferences, raising awareness of UKHLS data and its use.
Start Year 2018
 
Description Understanding Society Biomarker Fellowships 
Organisation University of Sheffield
Country United Kingdom 
Sector Academic/University 
PI Contribution 6 Fellowships offered by Understanding Society
Collaborator Contribution Research Projects using Understanding Society data, in collaboration with expert team members.
Impact Research projects have just commenced - publications and events are planned for later in 2018 when the projects are further developed. Each of the Fellows will present their research at international conferences, raising awareness of UKHLS data and its use.
Start Year 2018
 
Description Vitamin D and T2D - Multi-ethnic Mendelian Randomization Study 
Organisation University of Oklahoma
Department Health Sciences Centre
Country United States 
Sector Academic/University 
PI Contribution Analysis submitted from the genetic and main survey data.
Collaborator Contribution Provided analysis plan for all involved. Wrote the manuscript to be submitted.
Impact Journal article written and ready for submission.
Start Year 2017
 
Title Stata software: bicop 
Description A new command, called BICOP, written for the statistical package Stata. The command allows the user to fit a model consisting of a pair of ordinal regressions with a flexible residual distribution, with each marginal distribution specified as a two-part normal mixture, and stochastic dependence governed by a choice of copula functions. 
Type Of Technology Software 
Year Produced 2015 
Impact The code is described in an Understanding Society Working Paper. It is being made freely available to potential users. We have had 8 requests so far. A revised version of the working paper describing the command and an application to Understanding Society data has been accepted for publication in the Stata Journal, and we expect its use to grow considerably when that article appears. 
URL https://www.understandingsociety.ac.uk/research/publications/working-paper/understanding-society/201...
 
Description 'HEALTHY & UNHEALTHY CONNECTIONS' article published in ESRC report Britain in 2016 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact An article outlining why biomarker data are important for soical science research, and illustrating with Understanding Society examples.
Year(s) Of Engagement Activity 2015
URL http://www.esrc.ac.uk/news-events-and-publications/publications/magazines-and-newsletters/britain-in...
 
Description (Mark Green) Poster at Public Health Science in Belfast 2018 (title was: Utilising machine learning approaches for comparing the contribution of different types of data for predicting an individual's risk of ill health) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Mark Green, Biomarker Fellow, had a poster at Public Health Science in Belfast last year (title was: Utilising machine learning approaches for comparing the contribution of different types of data for predicting an individual's risk of ill health). The abstract was published in the Lancet but I guess that does count? Here is the link to the abstract https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(18)32877-0.pdf).
Year(s) Of Engagement Activity 2018
URL https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(18)32877-0.pdf
 
Description Allostatic load construction changes with age 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact presentation at the biomarker conference demonstrating that the construction of allostatic load changes with age.
Year(s) Of Engagement Activity 2018
 
Description Amanda Hughes: Guardian online article: Study dispels myth of links between poverty and weight 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact https://www.theguardian.com/society/2017/jan/29/unemployed-more-likely-to-be-underweight-than-obese
Year(s) Of Engagement Activity 2017
URL https://www.theguardian.com/society/2017/jan/29/unemployed-more-likely-to-be-underweight-than-obese
 
Description Amanda Hughes: Independent online - Renters have higher levels of harmful stress markers than home owners, study finds 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Amanda Hughes: Independent online - Renters have higher levels of harmful stress markers than home owners, study finds
Year(s) Of Engagement Activity 2019
URL https://www.independent.co.uk/news/health/renting-stress-health-homeowner-mortgage-flat-terrace-bene...
 
Description Amanda Hughes: Independent online: Renters are more likely to have poor health than those who own, researchers say 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Amanda Hughes: Independent online: Renters are more likely to have poor health than those who own, researchers say
Year(s) Of Engagement Activity 2019
URL https://www.independent.co.uk/news/health/renting-owning-property-real-estate-health-a8750651.html
 
Description Amanda Hughes: POST presentation: Unemployment, underweight and obesity: findings from UKHLS. Presentation for the UK Parliamentary Office of Science and Technology, Westminster, 20 July 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact POST presentation: Unemployment, underweight and obesity: findings from UKHLS.
Presentation for the UK Parliamentary Office of Science and Technology, Westminster, 20 July 2017
Year(s) Of Engagement Activity 2017
 
Description Amanda Hughes: Podcast - Unemployment, underweight, and obesity: Findings from Understanding Society (UKHLS) (LSE/DWP seminar: joint hosted and attended by Department of Work and Pensions Staff) 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Amanda Hughes: Podcast - Unemployment, underweight, and obesity: Findings from Understanding Society (UKHLS) (LSE/DWP seminar: joint hosted and attended by Department of Work and Pensions Staff)
Year(s) Of Engagement Activity 2017
URL http://sticerd.lse.ac.uk/case/_new/events/audio.asp?id=5982http://sticerd.lse.ac.uk/case/_new/events...
 
Description Amanda Hughes: Telegraph online: Why living in a detached house could be better for health 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Amanda Hughes: Telegraph online: Why living in a detached house could be better for health
Year(s) Of Engagement Activity 2019
URL https://www.telegraph.co.uk/science/2019/01/14/living-detached-house-could-better-health/
 
Description Amanda Hughes: The Conversation: Difficult childhood experiences could make us age prematurely - new research 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Amanda Hughes: The Conversation: Difficult childhood experiences could make us age prematurely - new research
Year(s) Of Engagement Activity 2018
URL https://theconversation.com/difficult-childhood-experiences-could-make-us-age-prematurely-new-resear...
 
Description Amanda Hughes: The Conversation: How renting could affect your health 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Amanda Hughes: The Conversation: How renting could affect your health.

Reported by the Metro, World Economic Forum, and Independent.

Generation Rent also sent the paper to the MHCLG private rented sector team.
Year(s) Of Engagement Activity 2019
URL https://theconversation.com/how-renting-could-affect-your-health-110334
 
Description Amanda Hughes: The Scotsman online: Levels of stress linked to the type of housing accommodation in UK 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Amanda Hughes: The Scotsman online: Levels of stress linked to the type of housing accommodation in UK
Year(s) Of Engagement Activity 2019
URL https://www.scotsman.com/news/health/levels-of-stress-linked-to-the-type-of-housing-accommodation-in...
 
Description Amanda Hughes: Times of Malta online: How renting could affect your health - and not for the better 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Amanda Hughes: Times of Malta online: How renting could affect your health - and not for the better
Year(s) Of Engagement Activity 2019
URL https://www.timesofmalta.com/articles/view/20190129/health-fitness/how-renting-could-affect-your-hea...
 
Description Amanda Hughes: presentation - Socioeconomic Position and DNA Methylation Age Acceleration Across the Life Course (Health Studies user conference 2018) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Amanda Hughes: presentation - Socioeconomic Position and DNA Methylation Age Acceleration Across the Life Course (Health Studies user conference 2018)
Year(s) Of Engagement Activity 2018
URL https://ukdataservice.ac.uk/eventsdocs/healthuserconfprog17jul18
 
Description BMI and Well-being- A Mendelian randomization study 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other audiences
Results and Impact Introduce genetic data as instrumental variables to explain causal effect of BMI on wellbeing.
Year(s) Of Engagement Activity 2018
URL https://www.pssru.ac.uk/blog/measuring-health-well-being-reaching-across-disciplinary-boundaries/
 
Description Biomarker Launch 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact To mark the first release of biomarker and genetics data on Wednesday 10th December, Understanding Society is hosting an event at The Royal Society for Public Health in London
For the first time, Understanding Society will release results from a wide range of blood analytes for over 13,000 people. In addition, the results from a genome-wide scan of 10,000 respondents who took part in a nurse health assessment will also be available. Both these new elements added to Understanding Society's existing social and economic data will combine to provide very rich research opportunities.

Aimed at social scientists who are interested to find out how to use the data in their research.
Year(s) Of Engagement Activity 2014
URL https://www.understandingsociety.ac.uk/2014/11/10/social-scientists-biomarkers
 
Description Biosocial research and policy 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Discussion on how biomarkers and biomarker research can be useful or used by policy makers and third sector organisations
Year(s) Of Engagement Activity 2018
 
Description CLOSER 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact CLOSER (UCL Institute of Education, University College London) has published a news story regarding Dr Davillas' research on the concordance of health states within couples. This news story has been read extensively and has sparked discussions regarding the need for a re-orientation of public health policy and the underlying research towards a family-centred focus.
Year(s) Of Engagement Activity 2017
URL https://www.closer.ac.uk/news-opinion/news/partners-health-inequalities/
 
Description CLOSER seminar: methods of data collection and implications for social science 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other audiences
Results and Impact CLOSER longitudinal studies seminar: methods and their implications for participation in social science studies
Year(s) Of Engagement Activity 2017
 
Description Closed door discussion with selective members at MCRI - 11 September 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Sharing of good practice in collecting BIomarker Data
Year(s) Of Engagement Activity 2017
 
Description Department of Health in Canberra - 6 September 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Presentation and discussion to department of health Australia on the role of biomarkers in policy research.
Year(s) Of Engagement Activity 2017
 
Description ESRC Staff seminar 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation and discussions with ESRC staff, and representatives from MRC and BBSRC, about the role of biomarkers and genetics in social science research.
Year(s) Of Engagement Activity 2015
 
Description Economics of Obesity Special Interest Group -iHEA 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Dr Davillas has served as a founder member of the Economics of Obesity Special Interest Group (EOSIG) within the iHEA.
He has been successfully involved in a number of activities within the EOSIG:
a) Enhance understanding of the prevention and treatment of obesity from an economics perspective;
b) Connect economists working in obesity across the world;
c) Share knowledge and provide support through the creation of a community of health economists specialized at the Economics of Obesity working together;
d) Provide input to policy development at an international level.
Year(s) Of Engagement Activity 2008,2017
URL https://www.healtheconomics.org/page/EOSIGMembers
 
Description Epigenetic Data Launch 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact We launched the Epigenetic dataset generated in Understanding Society to a mixed audience at a day event in London. This involved delegated from all over the country. Our aim was to inform as many potential users of the dataset of the strengths of this type of data in social and biological sciences and how they could access the data.
Year(s) Of Engagement Activity 2017
URL https://www.understandingsociety.ac.uk/events/2017/04/27/understanding-society-epigenetics-data-laun...
 
Description Epigenetic Data Launch 27 April 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Introducing understanding society biomarker data to leading experts in a new field of the study of epigenetics. Increased understanding of data and data use.
Year(s) Of Engagement Activity 2017
 
Description Epigenetics For Social Scientists 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact A workshop designed to introduce and help social scientists use the epigenetic data within Understanding Society. This was a whole day workshop with lectures and an interactive session.
Year(s) Of Engagement Activity 2018
 
Description Genetic Data in Understanding Society 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact November 2015
This course will introduce genetic terms relevant to social science, the genetic data available in Understanding Society and procedures to access these data, the structure of these data and provide worked examples of genetic analyses.

In Wave 2 for the general population sample and wave 3 for the BHPS sample Understanding Society included a nurse visit. DNA was extracted from a blood sample that was collected from participants and genetic data from these samples have been deposited in the European-phenome archive.

This half day workshop will consist of an introductory presentation on basic genetics, followed by an overview of the genetic data in Understanding Society. This will be followed by an example of genetic analysis that participants will work on in the computer lab. The focus of the course is on understanding how the genetic data might be useful to social science analyses, introduction to the format of genetic data and how to prepare them for analyses, rather than on analysis methods.
Year(s) Of Engagement Activity 2015
URL https://www.understandingsociety.ac.uk/events/2015/11/06/Genetic%20Data%20in%20Understanding%20Socie...
 
Description Genetics For Social Scientists 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact A workshop designed to introduce and help social scientists use Mendelian Randomization with genetic data of Understanding Society. This was a whole day workshop with lectures and an interactive session.
Year(s) Of Engagement Activity 2018
URL https://www.understandingsociety.ac.uk/documentation/training/genetics-for-social-science-workshop
 
Description Genetics in social science research 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Symposium presentation discussion the use of genetics for social science
Year(s) Of Engagement Activity 2018
 
Description Glasgow seminar 2 February 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation to introduce biomarker and genetic research in Understanding Society to MRC unit in Glasgow
Year(s) Of Engagement Activity 2017
 
Description Guardian article 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact The Guardian has published an in-depth feature on Dr Davillas' (along with Benzeval and Kumari) research on biomarkers using UKHLS. This article has been shared with social media more than 450 times and has received more than 160 comments from general public. This article has sparked several discussions regarding the potential of biomarkers for social and economic research.
Year(s) Of Engagement Activity 2017
URL https://www.theguardian.com/inequality/2017/oct/10/how-your-blood-may-predict-your-future-health-bio...
 
Description Guardian podcast interview 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Interview with the Guardian for a podcast
Year(s) Of Engagement Activity 2017
 
Description Interview for national newspaper (the Observer) 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact I was interviewed for the Observer newspaper about my research into the relationship of Body Mass Index (BMI) and unemployment, suggesting that underweight may explain more ill-health among jobseekers than previously realized. This resulted in the article linked below.
Year(s) Of Engagement Activity 2017
URL https://www.theguardian.com/society/2017/jan/29/unemployed-more-likely-to-be-underweight-than-obese
 
Description Interview with the Guardian 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Interview for an article in the Guardian
Year(s) Of Engagement Activity 2017
 
Description Invited Talks -- Zhongshan University (Guangzhou, China), Nankai University (Tianjin, China), Yunnan Normal University (Kunming, China) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Audience are mainly postgraduate students from medical/statistical research area and they were introduced about Understanding Society (UKHLS) Study, how to apply and access data, what the potential health related scientific questions that could be answered using Understanding Society data.
Year(s) Of Engagement Activity 2017
 
Description Invited talk - City, London 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Dr Davillas has been invited by the School of Health Sciences at City, University of London to give a talk regarding the potential of biomarker data for social science research. An audience of about 50 (undergraduate and postgraduate) students and academics is expected (December 2018).
Year(s) Of Engagement Activity 2018
 
Description Invited talk - U of Barcelona 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Dr Davillas has been invited by the Department of Economics, University of Barcelona to give a talk regarding the potential of biomarker data for social science research. An audience of about 40 (undergraduate and postgraduate) students, academics and (local government) health policymakers is expected to attend (November 2018).
Year(s) Of Engagement Activity 2008,2018
 
Description Invited workshop for Understanding Society Scientific Conference (Clarke) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact An invited workshop "Longitudinal modelling with longitudinal households" for the Understanding Society Scientific Conference. The session was attended by a variety of academic and non-academic users of BHPS and Understanding Society.
Year(s) Of Engagement Activity 2015
URL https://www.understandingsociety.ac.uk/scientific-conference-2015/papers/75
 
Description KEY NOTE - Portugese Health Economics Conference - October 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Keynote presentation to Portugese conference on methodological innovation in Health Research
Year(s) Of Engagement Activity 2017
 
Description Machine Learning in Geography. Geography in Machine Learning - RGS-IBG Annual International Conference 2018 (Mark Green) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Mark Green, Biomarker Fellow, co-organised a session at the RGS-IBG Annual Conference in 2018 on Machine Learning and also gave a presentation as well (see here for more details http://conference.rgs.org/AC2018/220)
Year(s) Of Engagement Activity 2018
URL http://conference.rgs.org/AC2018/220
 
Description Masterclass on allostatic load - 13 March 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact To introduce understanding society biomarker data to leading experts internationally in the field
Year(s) Of Engagement Activity 2017
 
Description Murdoch Childrens Research Institute (MCRI) 11 september 2017 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation and discussion with the Murdoch institute on collecting Biomarkers in the general population
Year(s) Of Engagement Activity 2017
 
Description NCRM course with UKHLS - methodological considerations in biosocial research using Understanding Society data 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Tarani Chandola course at Southampton - awareness raising and capacity building.
Year(s) Of Engagement Activity 2017
 
Description NCRM, UKHLS and ICLS Autumn School 2016 for Postdoctoral Researchers 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Training event for early career researchers on biomarkers in social science
Year(s) Of Engagement Activity 2016
 
Description New forms of data: Glasgow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact New forms of data: introduction to the biomarker data in social science surveys to enable new users of the these datasets. Workshop organised by CLOSER, the UKDA and Understanding Society
Year(s) Of Engagement Activity 2017
 
Description New forms of data: London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact new forms of data in London.
Year(s) Of Engagement Activity 2018
 
Description Nitzan Peri-Rotem: The role of biomedical factors in explaining fertility differences by education. Presentation - British Society for Population Studies annual meeting. 11 September 2018. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Nitzan Peri-Rotem: The role of biomedical factors in explaining fertility differences by education. Presentation - British Society for Population Studies annual meeting. 11 September 2018.
Year(s) Of Engagement Activity 2018
 
Description Obesity opinion article 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Dr Davillas has been invited by the ESRC to contribute an opinion article regarding his research on the Economics of Obesity (ESRC Society Now magazine, Winter 2017, issue 27).
Society Now is the regular magazine of the ESRC, bringing the latest and most topical social science research to key opinion formers in business, government and the voluntary sector. It is published four times a year and highlights research by the UK's leading social scientists. This opinion article demonstrates the importance of the survey measurement of obesity on inequalities and social science research.
Year(s) Of Engagement Activity 2016
URL https://esrc.ukri.org/files/news-events-and-publications/publications/magazines/society-now/society-...
 
Description Oxford NCRM Summer School 2017 for Postdoctoral Researchers 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Lecture to researchers interested in incorporating genetics in their social science analyses.
Year(s) Of Engagement Activity 2017
 
Description Politico Interview 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Dr Davillas has been interviewed by Politico.com regarding the potential of biomarker information for health policy. This article has been read extensively and has sparked several discussions in social media on the value of objective measures of health for health policy evaluation.
Year(s) Of Engagement Activity 2017
URL https://www.politico.com/agenda/story/2018/01/10/long-term-health-nation-problems-000613
 
Description Presentation for Parliamentary staff at POST (Parliamentary Office of Science and Technology) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact I presented new work looking into employment and health at a lunchtime meeting for staff at the Parliamentary Office of Science and Technology (POST). This was based on recently published research into the relationship of Body Mass Index (BMI) and unemployment, suggesting that underweight may explain more ill-health among jobseekers than previously realized. Also presenting was Tarani Chandola, with his research on how poor quality work may be worse for some aspects of health than no work at all. The purpose of the session was to communicate to policymakers recent findings from UKHLS indicating that received wisdom about the relationships of work, non-work and health may need to be reconsidered. After each presentation, the researchers asked questions about findings and what we thought were the most important implications for policymakers.
Year(s) Of Engagement Activity 2017
URL https://www.iser.essex.ac.uk/2017/07/24/iser-at-post
 
Description Presentation for an audience including DWP staff and academics 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact I presented at a lunchtime seminar in the CASE (Centre for Analysis of Social Exclusion) Welfare Policy and Analysis series. Sponsored by the DWP, these seminars are attended by DWP staff as well as LSE academics and the general public. This was based on recently published research into the relationship of Body Mass Index (BMI) and unemployment, suggesting that underweight may explain more ill-health among jobseekers than previously realized, and was followed by a Q&A.
Year(s) Of Engagement Activity 2017
URL http://sticerd.lse.ac.uk/case/_new/events/audio.asp?id=5982
 
Description Presentation on UK causal inference meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact The workshop is an annual meeting for statistician exchange ideas and findings in causal effect research area. Understanding Society genetic data was used in presentation as a good practical example of how genetic data can be used in helping explaining causal effect of health exposure on social outcomes.
Year(s) Of Engagement Activity 2017
URL https://sites.google.com/site/ukcausalinferencemeeting/
 
Description Psychological stress, health and potential biological mechanisms 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at a mini-conference on stress: Invited to speak on the biological pathways that may mediate social differences in health:
Year(s) Of Engagement Activity 2018
 
Description RMF video 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact What is? video on biosocial research on NCRM website
Year(s) Of Engagement Activity 2016
 
Description Research Methods Festival 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact RMF event to raise awareness of value of biomarkers in social science research
Year(s) Of Engagement Activity 2016
 
Description SLLS: social to biological workshop 2016 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Workshop illustrating the use of biomarkers in social science
Year(s) Of Engagement Activity 2017
 
Description SLLS: social to biological workshop 2017 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact SLLS workshop illustrating the use of biomarkers to social science researchers
Year(s) Of Engagement Activity 2017
 
Description SLLS: social to biological workshop 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact training workshop
Year(s) Of Engagement Activity 2018
 
Description Social science and epigenetics network 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation to network of researchers engaged in social science an epigenetics
Year(s) Of Engagement Activity 2018
 
Description The Oxford NCRM (National Centre for Research Methods) Summer School 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact An introduction to combining social science and molecular genetic research offer graduate students, early career researchers and researchers interested in entering this topic a unique introductory course.

The programme consisted of morning lectures by top scholars in the emerging field of 'sociogenomics', including Dalton Conley (Princeton), Ben Domingue (Stanford), Melinda Mills (Oxford), David Steinsaltz (Oxford), Meena Kumari (Essex), Cecilia Lindgren (Oxford). Afternoon lectures consist of hands-on computer lab training by Oxford-based researchers Nicola Barban, Felix Tropf, Stine Møllegaard, Maria Christodoulou, Melissa Smart (Essex), and Yanchun Bao (Essex).

The course equipped students with a unique insight into the emerging topic of sociogenomics and the most cutting-edge methodological techniques in this area of research. The focus was on understanding the key substantive research questions in this area, an overview of UK data that is increasingly available, hands-on computer lesson of how to work with genetic data, and an introduction into the current methodological techniques used in the field.
Year(s) Of Engagement Activity 2017
URL http://www.oxfordsociogenetics.com/
 
Description UK evidence on environmental and health behaviours 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Workshop bringing together academics and policy makers in health and environment to consider key questions and data available to address them.
Year(s) Of Engagement Activity 2015
 
Description Understanding Society Biomarker Conference (15 March 2017) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact A new conference which showcased work from researchers using Understanding Society biomarker data to investigate links between health and social and economic factors in contemporary Britain.

The Understanding Society Biomarker Conference was held on 15th March 2017 at RIBA, London gave researchers the opportunity to showcase their current and ongoing work based on Understanding Society biomarker data.

The conference which took place on 15th March 2017 at RIBA, London saw presentations on topics such as non-standard work-hours, unemployment and financial insecurity, caregiving, volunteering, and neighbourhood differences in morbidity.

As well as hearing the findings from these different research projects, there was ample time for discussion of analytical issues raised by the presentations and more generally.

The Biomarker Team from Understanding Society was also on hand to answer any additional questions that users may have had about the data.
Year(s) Of Engagement Activity 2017
URL https://www.understandingsociety.ac.uk/events/2017/03/15/understanding-society-biomarker-conference
 
Description Understanding Society Biomarker Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact July 2015
In Wave 2 for the general population sample and wave 3 for the BHPS sample Understanding Society included a nurse visit. The physical measures and blood analytes data from these interviews have been deposited at the UK Data Service. The purpose of this workshop is to introduce the blood analytes; and outline some of the issues that need to be considered in analysing them.
Year(s) Of Engagement Activity 2015
URL https://www.understandingsociety.ac.uk/events/2015/07/20/understanding-society-biomarkers-workshop
 
Description Understanding Society Biomarker Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Biomarker Workshop November 2014
In Wave 2 for the general population sample and wave 3 for the BHPS sample UKHLS included a nurse visit. The physical measures data from these interviews have already been deposited at the UK Data Service. In December 2014, blood analytes will be deposited. The purpose of this training course is to introduce the blood analytes included in the UKHLS/BHPS datasets; and outline some of the issues that need to be considered in analysing them.
Year(s) Of Engagement Activity 2014
URL https://www.understandingsociety.ac.uk/events/2014/11/18/ukhls-biomarkers-training-course
 
Description Understanding Society Lifecourse and Health Masterclass 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact This course was led by international expert Dr Michelle Kelly-Irving from INSERM, Toulouse University. It introduced lifecourse theories from across biological and social sicence disciplines, and then through group work supported participants to develop research proposals to investigate lifecourse questions with Understanding Society data. It was open to all but geared to early career and PhD students from both social and biological sciences with an interest in health inequalities and the life course approach.
Year(s) Of Engagement Activity 2016
URL https://www.understandingsociety.ac.uk/2016/01/28/masterclass
 
Description Understanding Society Masterclass Combining Sociology and Biology (13 March 2017) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact This workshop with Professor Teresa Seeman from the University of California, Los Angeles helped researchers better understand the interaction of the social environment and health with a focus on the biological pathways and the potential to investigate them with Understanding Society.

The event was held at the Royal Institute of British Architects, London.

As part of Understanding Society's £1.4 million biomarker research programme, this course encouraged an interdisciplinary approach to research on health.

A mixture of lectures, seminars and group activities will focus on:

The interaction between social and biological processes
Opening up the research process: how to go from general ideas, to research questions to testing hypotheses
Familiarisation with Understanding Society and the BHPS
Year(s) Of Engagement Activity 2017
URL https://www.understandingsociety.ac.uk/events/2017/03/13/masterclass
 
Description Understanding Society and ELSA genetic workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact 20 researchers attended this workshop. The audience was composed of social scientists who wanted to learn about genetics and the use of these types of data for social science research.
Year(s) Of Engagement Activity 2015
 
Description masterclass: allostatic load 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Masterclass on allostatic load: with Teresa Seeman
Year(s) Of Engagement Activity 2017
 
Description masterclass: lifecourse 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Presentation in masterclass on lifecourse theories and embodiment
Year(s) Of Engagement Activity 2016
 
Description understanding health and society: the role of biomarkers article published in Taking the Long View 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Article outlining importance of biomarkers for policy and social science research
Year(s) Of Engagement Activity 2015
URL https://www.iser.essex.ac.uk/system/annual_reports/file_downloads/000/000/018/original/ISER-Report-2...