Epigenetic reprogramming and cloning
Lead Research Organisation:
Babraham Institute
Department Name: Epigenetics
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
People |
ORCID iD |
| Wolf Reik (Principal Investigator) | |
| Wendy Dean (Co-Investigator) |
Publications
Lucifero D
(2006)
Artificial sperm and epigenetic reprogramming.
in Nature biotechnology
Probst AV
(2007)
Structural differences in centromeric heterochromatin are spatially reconciled on fertilisation in the mouse zygote.
in Chromosoma
Reik W
(2007)
Stability and flexibility of epigenetic gene regulation in mammalian development.
in Nature
Reik W
(2015)
Germline and Pluripotent Stem Cells.
in Cold Spring Harbor perspectives in biology
| Description | House of Lords Report on Genomic Medicine |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | BBSRC LINK Grant |
| Amount | £468,118 (GBP) |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Role of Np95 in epigenetic reprogramming |
| Organisation | RIKEN |
| Country | Japan |
| Sector | Public |
| PI Contribution | We are analysing the effects of Np95 deletion in zygotes and early embryos |
| Collaborator Contribution | Contribution of unpublished conditional knockout in the key epigenetic regulator Np95 |
| Impact | The first results have been obtained and look quite interesting |
| Start Year | 2008 |
| Description | Public Lecture Cambridge Science Festival 2007 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | Yes |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Gave a 1 hour lecture entitled 'Who do you think you are' on Epigenetics and Human development/disease to a general educated audience Had a few follow up requests for additional information from some of the members of the audience |
| Year(s) Of Engagement Activity | 2007 |