Biochemical characterisation of pivotal enzymes involved in mycobacterial mycolic acid biosynthesis

Lead Research Organisation: University of Birmingham
Department Name: Sch of Biosciences

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

10 25 50

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Bhatt A (2007) Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice. in Proceedings of the National Academy of Sciences of the United States of America

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Dover LG (2007) Regulation of cell wall synthesis and growth. in Current molecular medicine

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Ghadbane H (2007) Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT). in Acta crystallographica. Section F, Structural biology and crystallization communications

 
Description Research Grant
Amount £420,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 04/2006 
End 10/2009
 
Description Research Grant
Amount £404,224 (GBP)
Funding ID G0901690 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 06/2010 
End 05/2013
 
Description The Mycobacterium tuberculosis Cell Envelope: unravelling complex cell wall assembly, degradation and re-cycling pathways
Amount £1,720,866 (GBP)
Funding ID MR/S000542/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 03/2019 
End 02/2024
 
Description BCG Vaccine and problems? 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact BBC Inside Out

None
Year(s) Of Engagement Activity 2007
 
Description New TB Drugs 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Interview for BBC Inside Out.

None
Year(s) Of Engagement Activity 2007
 
Description New TB drug targets and vaccines 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact An interview with the BBC Inside Out show.

None
Year(s) Of Engagement Activity 2007
 
Description New TB drugs and vaccines? 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Interview with the BBC and Inside Out Show for the West Midlands.

None
Year(s) Of Engagement Activity 2007
 
Description New TB drugs? 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Interview and presentation for the BBC Inside Out

None
Year(s) Of Engagement Activity 2007