Pathfinder proposal: RNAi screens to identify genetic modifiers of Huntingtons disease in Drosophila models

Lead Research Organisation: University of Cambridge
Department Name: Medical Genetics

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Publications

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Rubinsztein DC (2005) Dyneins, autophagy, aggregation and neurodegeneration. in Autophagy

 
Description MRC Programme Grant
Amount £2,968,260 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 01/2007 
End 12/2011
 
Description Talks at international conferences 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact India-EMBO Autophagy Symposium (Bubaneswar 2017), Autophagy as a Common Pathway in Diseases (NIH, Bethesda 2018), Gordon Conference -Autophagy in Stress, Development and Disease (Il Ciocco, 2018), Interact (Munich, 2018), Autophagy and Neuroprotection (Teaching course, Venice 2018), 83rd Harden Conference Autophagy - from Molecules to Disease (Warwick 2018), Gordon conference - Neurobiology of Brain Disorders (Castelldefels, Spain, 2018), Workshop on Autophagy in model organisms (Budapest, 2018), Autophagy in the healthy and diseased brain - Lake Como School of Advanced Studies (2018), 7th International Student Symposium conducted by the International Max Planck Research School in Chemical and Molecular Biology (Dortmund) (2018)
Year(s) Of Engagement Activity 2018
 
Description Talks at international conferences 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Keystone Symposium: Autophagy: From Model Systems to Therapeutic Opportunities (Santa Fe 2019), Autophagy, Inflammation & Metabolism Annual Meeting & Symposium (Albuquerque (2019), British Inflammation Research Association meeting on Autophagy (2019), FASEB - The Protein Aggregation Conference (Snowmass, 2019), Gordon Research Conference on Stress Proteins in Growth, Development and Disease (Barga, 2019), Imperial College Alzheimer's Research Network Symposium (London 2019), EMBO Autophagy Workshop 2019 (Crieff, Scotland), European Society of Neurochemistry 2019 (Milan), Basel Life - Aging and drug discovery and AI (Basel, 2019), Inaugural International Symposium of Cell Fate Determination (Shanghai 2019)
Year(s) Of Engagement Activity 2019
 
Description Talks for Medical Students societies 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Undergraduate students
Results and Impact St Johns College Medical Society Cambridge (2017)
Trinity College Medical Society (2019)
Year(s) Of Engagement Activity 2017,2019
 
Description Talks for lay audiences/patients 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Patients, carers and/or patient groups
Results and Impact Addenbrooke's Hospital Huntington's disease patients (2018); Addenbrooke's Hospital Parkinson's disease patients (2018)
Year(s) Of Engagement Activity 2018