PF181: Psychological mechanisms of antidepressant drug action

Lead Research Organisation: University of Oxford
Department Name: Experimental Psychology

Abstract

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Description MRC Biomarkers Grant
Amount £350,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2008 
End 10/2012
 
Title Emotional Test Battery 
Description This battery of emotional tasks was validated by the study conducted under this MRC award 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2009 
Provided To Others? Yes  
Impact Interest and funding from the pharmaceutical industry 
 
Description Bangor collaboration 
Organisation Bangor University
Country United Kingdom 
Sector Academic/University 
PI Contribution Stimulated a research collaboration with researchers in Bangor
Collaborator Contribution Research study collaboration
Impact publication: 19250683 This collbaoration involves interaction between the following disciplines: experimental psychology, clinical psychiatry and psychopharmacology
Start Year 2006
 
Title Biomarker : antidepressant drug action 
Description Our models of emotional processing are gaining increasing interest as biomarkers of effective antidepressant drug action. Collaborations with pharmaceutical industry have increased and we have used these models in phase 1 studies with novel compounds as proof of concept. 
Type Support Tool - For Medical Intervention
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2008
Development Status Actively seeking support
Impact Increased funding from industry; useful information on dosing requirements for novel compounds. 
 
Company Name p1vital 
Description www.p1vital.com 
Year Established 2004 
Impact Steering experimental medicine models for CNS drug development
Website http://www.p1vital.com
 
Description Article in local press 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Interview a journalist from Cherwell News who wrote a short piece in the the local newspaper

Increase in volunteer numbers
Year(s) Of Engagement Activity 2006
 
Description Presentation at GP clinics 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Multiple sessions at local GPs to present findings and discuss implications

Interest of local GP community increased; better understanding of psychological effects of drug treatments; better communication to patient groups
Year(s) Of Engagement Activity 2007,2008
 
Description Press Briefing 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Press Briefing in science media centre.

Article appeared in BBC news online http://news.bbc.co.uk/1/hi/health/8304782.stm
Year(s) Of Engagement Activity 2009
URL http://news.bbc.co.uk/1/hi/health/8304782.stm
 
Description Public Lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact The annula Monica Fooks lecture, attended broadly by the public and by people within the University
Year(s) Of Engagement Activity 2016
 
Description Scientific Mind Article 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? Yes
Type Of Presentation Paper Presentation
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact This publication will appear in December 2013.
Year(s) Of Engagement Activity 2013