BRAIN UK: accessing NHS tissue archives for neuroscience research

Lead Research Organisation: University of Southampton
Department Name: Clinical Neurological Sciences

Abstract

The brain (and associated components including the spinal cord, nerves, muscle and eye) is important to us, essentially making us humans and giving us our identity and self awareness. It is composed of cells which, once formed in infancy, have to last us a lifetime. Inevitably, the brain is complex and may malfunction. Damage to, or disease of, any part of the nervous system is likely to result in physical disability, mental illness or may cause death. Study of brain tissue samples retained at post mortem examinations has led to many of the advances in our understanding of neurological disease in the last few decades, and led to new treatments. Animal models of human brain diseases have been helpful, but have the disadvantage that they are not the actual human disease itself, and therefore have in some instances been misleading. Work performed in the NHS by neuropathologists over the past 30-40 years across the UK, and which continues, has led to very substantial collections of stored brain tissue samples. The objective of BRAIN UK is to catalogue these samples and address ethical and legal issues, in order to allow release of appropriate samples for new research studies. The stream-lined application/review process and generic ethical approval has removed many of the bureaucratic hurdles until recently hindering researchers. Researchers can now access tissue for their studies from more than 60,000 cases through BRAIN UK. The ultimate aim, of course, is to further improve our understanding of the mechanisms involved in the development of neurological disease and eventually provide new forms of treatment or prevention for diseases of the nervous system.

Technical Summary

BRAIN UK is a virtual brain bank providing access to human tissue from more than 60,000 cases held in 13 NHS regional neuroscience centres across the UK. All ethical and NHS R&D permissions have been granted for blanket use of this tissue for researchers in the UK and overseas, so saving researchers considerable time and effort by removing these bureaucratic barriers to the use of human tissue. Many substantial advances in the understanding of neurological diseases have been made over the past decades from direct observations made on post mortem human tissue and further advances are to be anticipated. Animal models of disease have an important role, but also have their limitations. Types of tissue encompassed by BRAIN UK are the brain and associated components including the spinal cord, nerves, muscle, eye and samples of other organs when relevant to neurological disease. BRAIN UK is not limited to diseases that can attract sufficient funding for dedicated brain banks and is therefore complementary to them. For example, BRAIN UK has many hundreds of cases of head injury, stroke and mental health disorders and also examples of many rare conditions such as Progressive multifocal leucoencephalopathy and Neuromyelitis optica. The work in collecting, processing, categorising and archiving the samples has already been performed within the NHS; in providing a mechanism for access to this tissue for research BRAIN UK provides exceptional added value. With this proposal for continued funding for BRAIN UK we aim to: continue providing access to tissue for researchers, further refine the database for greater precision in access to information and put into place a mechanism to permit inclusion of new cases obtained now and into the future.

Organisations

Publications

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Bödör C (2020) Molecular Subtypes and Genomic Profile of Primary Central Nervous System Lymphoma. in Journal of neuropathology and experimental neurology

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Durnford A (2015) Haemoglobin scavenging after subarachnoid haemorrhage. in Acta neurochirurgica. Supplement

 
Description University of Southampton Information Security Policy
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
 
Description Brain UK biopsy extension
Amount £90,000 (GBP)
Funding ID 512921101 
Organisation Brainstrust 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2013 
End 07/2016
 
Description Project grant G1100578
Amount £352,784 (GBP)
Funding ID G1100578 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 10/2011 
End 10/2015
 
Title BRAIN UK Database 
Description BRAIN UK continues to collect a prescribed linked-anonymised dataset relating to both post mortem and surgical cases archived by participating centres. 
Type Of Material Database/Collection of data 
Year Produced 2010 
Provided To Others? Yes  
Impact The BRAIN UK database is used to identify cases of interest to the research community and to aid participating centres in the acquisition of these cases for research purposes. The database has also provided information relating to the incidence of specified diseases for epidemiological purposes. 
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Barking, Havering and Redbridge University Hospitals NHS Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Barts Health NHS Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Cambridge University Hospitals NHS Foundation Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Cardiff and Vale University Health Board
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Great Ormond Street Hospital (GOSH)
Country United Kingdom 
Sector Hospitals 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Hull and East Yorkshire Hospitals NHS Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Imperial College Healthcare NHS Trust
Country United Kingdom 
Sector Hospitals 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation King's College University Hospital NHS Trust
Country United Kingdom 
Sector Hospitals 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Lancashire Teaching Hospitals NHS Foundation Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Leeds Teaching Hospitals NHS Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation NHS Greater Glasgow and Clyde (NHSGGC)
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation NHS Lothian
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Newcastle upon Tyne Hospitals NHS Foundation Trust
Country United Kingdom 
Sector Academic/University 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation North Bristol NHS Trust
Country United Kingdom 
Sector Academic/University 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Nottingham University Hospitals NHS Trust
Country United Kingdom 
Sector Academic/University 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Oxford University Hospitals NHS Foundation Trust
Country United Kingdom 
Sector Academic/University 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Plymouth Hospitals NHS Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Royal Free London NHS Foundation Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Salford Royal NHS Foundation Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation Sheffield Teaching Hospitals NHS Foundation Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation South Tees Hospitals NHS Foundation Trust
Department Department of Cellular Pathology
Country United Kingdom 
Sector Hospitals 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation St George's Healthcare NHS Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation The Walton Centre NHS Foundation Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation University College London Hospitals NHS Foundation Trust
Country United Kingdom 
Sector Academic/University 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation University Hospital Southampton NHS Foundation Trust
Country United Kingdom 
Sector Hospitals 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description BRAIN UK network of participating neuropathology centres 
Organisation University Hospitals Birmingham NHS Foundation Trust
Country United Kingdom 
Sector Public 
PI Contribution Formation of BRAIN UK
Collaborator Contribution Collaboration to provide data about archives and to satisfy requests for tissue. Supplying of tissue to ethically approved studies.
Impact Formation of BRAIN UK database. Provision of brain tissue for research.
Start Year 2008
 
Description Brain Tumour Research 
Organisation Brain Tumour Research
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution We have provided expertise relating to the establisment of a 'virtual brainbank' to utilise extant and future surgical specimens maintained by UK neuropathology centres for high quality research.
Collaborator Contribution Brain Tumour Research provides funding for 1 x BRAIN UK post (MSA Grade 4) to enable the inclusion of neurosurgical tumour biopsies.
Impact Current establisment of protocols and procedures relating to BRAIN UK 'virtual brainbank' dedicated to surgical specimens. This primarily relates to obtaining mandatory regulatory approvals both nationally and locally.
Start Year 2013
 
Description Brain Tumour Research 
Organisation Brainstrust
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution We have provided expertise relating to the establisment of a 'virtual brainbank' to utilise extant and future surgical specimens maintained by UK neuropathology centres for high quality research.
Collaborator Contribution Brain Tumour Research provides funding for 1 x BRAIN UK post (MSA Grade 4) to enable the inclusion of neurosurgical tumour biopsies.
Impact Current establisment of protocols and procedures relating to BRAIN UK 'virtual brainbank' dedicated to surgical specimens. This primarily relates to obtaining mandatory regulatory approvals both nationally and locally.
Start Year 2013
 
Description MRC UK Brain Banks Network 
Organisation Medical Research Council (MRC)
Country United Kingdom 
Sector Public 
PI Contribution BRAIN UK compliments the tissue that the other brain banks within the MRC network provide. BRAIN UK (through data supplied by the participating neuropathology centres) have identified very useful quantities of rare neurological diseases and disorders as well as larger quantities of common and medically important disorders (such as stroke) and tumours that are currently not catered for by existing brain banking facilities. Participation at meetings and training events ensures that BRAIN UK's experiences of working with researchers are represented and that the brain banks work towards common aims.
Collaborator Contribution By 2015 BRAIN UK collaborating centres contributed data relating to over 130,000 available research cases to the centralised BRAIN UK database.
Impact No formal outcomes.
Start Year 2009
 
Description Advertisement via Association of British Neuropathologists (ABN) 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Type Of Presentation Paper Presentation
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Dissemination of BRAIN UK advertisement in January 2012 to ABN membership via e-mail.

Informal enquiries regarding the availability of tissue for research purposes and formally submitted applications.
Year(s) Of Engagement Activity 2012
 
Description Annual Report to Research Ethics Committee 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Annual report and update submitted to South Central - Southampton B Research Ethics Committee (formerly Southampton and South West Hampshire Research Ethics Committee B).

Allowed study to continue.
Year(s) Of Engagement Activity 2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020
 
Description Annual Report to the British Neuropathological Society 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Brief update delivered to the British Neuropathological Society Business Meeting as part of their annual meeting. Main aim is to keep the Neuropathology community aware of the work of BRAIN UK with the intention to keep receiving their support through the supply of data and tissue and for them to recommend the service to researchers. Also, to maintain engagement with neuropathologists and researchers and ensure that we are meeting their current and future needs.

Encouraged participation in BRAIN UK
Year(s) Of Engagement Activity 2011,2012,2013,2014,2015,2016,2017,2018,2019,2020
 
Description Annual report to the BRAIN UK Committee 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Annual meeting of BRAIN UK committee. Metrics data supplied to members to give an insight into how study is progressing, intention is to provide a support and challenge environment. As the study and the format of the meeting is well established good level of discussion around direction of the study with supportive suggestions for future direction and practical offers of support.
Year(s) Of Engagement Activity 2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020
 
Description BRAIN UK Website 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Creation and updates of BRAIN UK website.
Major redesign in 2015 to engage researchers, participating centres and the general public.
Further improvements made in 2019 to make navigation easier and the website more visual/engaging.
Year(s) Of Engagement Activity 2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020
URL http://www.brain-uk.org
 
Description BRAIN UK biopsy extension press release 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact BRAIN UK biopsy extension press release published on some trust websites and local news papers such as the Daily Echo in Southampton.
Year(s) Of Engagement Activity 2014
 
Description International Society for Neuropathology, Rio de Janeiro, Brazil, September 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation poster presentation
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Poster detailing BRAIN UK presented at the XVIII International Congress of Neuropathology held in Rio de Janeiro in September 2014.

Informal enquiries regarding the availability of tissue for research purposes.
Year(s) Of Engagement Activity 2014
 
Description Interview promoting the launch of BRAIN UK biopsy extension on JACK FM 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Radio interview promoting the launch of the BRAIN UK biopsy extension on Jack FM.
Year(s) Of Engagement Activity 2014
 
Description Interview promoting the launch of BRAIN UK biopsy extension on Wave 105 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Radio interview promoting the launch of the BRAIN UK biopsy extension on Wave 105.
Year(s) Of Engagement Activity 2014
 
Description Linkage from MRC Brain Banks Network website 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Link from the MRC Brain Banks Network http://www.mrc.ac.uk/research/facilities/brain-banks/access-for-research/ to promote the usage of BRAIN UK.
Year(s) Of Engagement Activity 2010,2011,2012,2013,2014,2015,2016,2017,2018,2019,2020
URL http://www.mrc.ac.uk/research/facilities/brain-banks/access-for-research/
 
Description Linkage to British Neuroscience Association (BNA) 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Type Of Presentation Paper Presentation
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact URL link established from ABN website (http://www.bna.org.uk/about/related-links.html) to BRAIN UK and dissemination of information in ABN e-Newsletter January 2012.

Informal enquiries to BRAIN UK concerning availability of tissue for research purposes.
Year(s) Of Engagement Activity 2012
URL http://www.bna.org.uk/about/related-links.html
 
Description Linkage to European Confederation of Neuropathological Societies (EuroCNS) 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Type Of Presentation Paper Presentation
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Dissemination of information in e-Bulletin and print version of journal 'Clinical Neuropathology'.

Informal enquiries to BRAIN UK concerning availability of tissue for research purposes.
Year(s) Of Engagement Activity 2012
 
Description National Cancer Research Institute Brain Tumour Clinical Studies Group (Bristol) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Platform presentation detailing BRAIN UK presented at the National Cancer Research Institute Brain Tumour Clinical Studies Group held in Bristol in June 2014.

Informal enquiries regarding the availability of tissue for research purposes.
Year(s) Of Engagement Activity 2014
 
Description National Cancer Research Institute Brain Tumour Clinical Studies Group (London) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Platform presentation detailing BRAIN UK presented at the National Cancer Research Institute Brain Tumour Clinical Studies Group held in London in April 2014.

Informal enquiries regarding the availability of tissue for research purposes.
Year(s) Of Engagement Activity 2014
 
Description Poster at Society for Neuro-Oncology Conference on Meningioma ( June 17-18, 2016 in Toronto, Ontario, Canada) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Interest in BRAIN UK
Year(s) Of Engagement Activity 2016
 
Description Poster at Southampton Neuroscience Group (SoNG) Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Poster to promote BRAIN UK project locally

Interest from the research community resulting in applications from local collaborators.
Year(s) Of Engagement Activity 2013,2014,2015
 
Description Poster presentation at European Congress of Neuropathology 2012 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation poster presentation
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Poster detailing BRAIN UK presented at the 10th European Congress of Neuropathology held in Edinburgh in June 2012.

Informal enquiries regarding the availability of tissue for research purposes.
Year(s) Of Engagement Activity 2012
 
Description Poster promoting BRAIN UK - British Neuropathological Society Meetings 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Type Of Presentation poster presentation
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact A poster was written and displayed at the 2009, 2014 and 2015 British Neuropathological Society Meetings at the Institute for Child Health in London. The poster was designed to update BNS of the activities of BRAIN UK and to advertise our intended service. It was also an opportunity to receive feedback and field questions from interested parties.
BRAIN UK staff is attending the BN meeting every year to promote the brain bank by interacting with the attendees and providing leaflets containing BRAIN UK information.

'The poster presentation at the 2009 and 2014 British Neuropathological Society Meetings enabled BRAIN UK to inform participating centres of our progress up to that time and to ensure their continued involvement and it also gave BRAIN UK an opportunity to enhance awareness of our aims and objectives amongst the wider research community.'
Year(s) Of Engagement Activity 2009,2014,2015
 
Description Presentation at British Neuro-Oncology Society Annual Meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Platform presentation (2014, 2016) to describe the biopsy extension to conference participants to raise awareness and support for project. Questions and discussion afterwards and two enquiries for applications for tissues and additional centre request to participate in the project.

Informal enquiries regarding the availability of tissue for research purposes.
Year(s) Of Engagement Activity 2014,2016
 
Description Presentation to South of England Brain Tumour Alliance (SEBTA) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Powerpoint presentation given at South of England Brain Tumour Alliance meeting October 2012 concentrating on the availability of brain tumour tissue through BRAIN UK.

Interest regarding the availability of paediatric tumour tissue.
Year(s) Of Engagement Activity 2012
 
Description Promotion of Corsellis Collection for "All in the Mind" on Radio 4 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Involvement with making of an "All in the Mind" Radio 4 programme , highlighting the closure the Corsellis Collection and the benefits of brain banking and research on human tissue. This resulted in further press interest and funding opportunities.
Year(s) Of Engagement Activity 2015
URL http://www.bbc.co.uk/programmes/b06r5d0h
 
Description Raise awareness of BRAIN UK with the CCLG 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Raise awareness of BRAIN UK activities with the Children's Cancer and Leukaemia Group Biological Studies Steering Group. Discussion on how can work together and how BRAIN UK fits with other brain banks.
Year(s) Of Engagement Activity 2014
 
Description Update Report to BRAIN UK Participating Centres 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Update of progress and invitations for applications for research projects disseminated amongst the UK Neuropathologist community.

Given the short period of time between the time of writing and the dissemination of information, there has been no discernable impact to date.
Year(s) Of Engagement Activity 2011,2012,2013,2014,2015,2016,2017,2018,2019,2020