Pump-Priming translational research initiative

Lead Research Organisation: University of Birmingham
Department Name: UNLISTED

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

Translational support posts for Tissue Biorepository and gene/immunotherapy portfolio

Publications

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Clayton RN (2016) Mortality in patients with Cushing's disease more than 10 years after remission: a multicentre, multinational, retrospective cohort study. in The lancet. Diabetes & endocrinology

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Crowley RK (2016) SFRP2 Is Associated with Increased Adiposity and VEGF Expression. in PloS one

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Dineen R (2017) Acromegaly. in QJM : monthly journal of the Association of Physicians

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Hardy RS (2016) 11ß-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation. in The Journal of pathology

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Jenkinson C (2016) High throughput LC-MS/MS method for the simultaneous analysis of multiple vitamin D analytes in serum. in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

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Larner DP (2016) Male 11ß-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease. in Endocrinology

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Morgan SA (2016) Glucocorticoids and 11ß-HSD1 are major regulators of intramyocellular protein metabolism. in The Journal of endocrinology

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Stewart PM (2016) Exploring Inpatient Hospitalizations and Morbidity in Patients With Adrenal Insufficiency. in The Journal of clinical endocrinology and metabolism

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Weigel M (2017) Immediate versus modified release hydrocortisone in mitotane-treated patients with adrenocortical cancer. in Clinical endocrinology

 
Title Human Biomaterials Resource Centre tissue collection 
Description Currently handling approximately 1100 samples/month of diverse tissue types for research groups and industry access. Agreements in place with all local NHS Trusts Number of consents = 2417 Number of samples stored = 19639 Number of applications received for use = 97 Number of samples released to projects = 2990 
Type Of Material Biological samples 
Year Produced 2010 
Provided To Others? Yes  
Impact The HBRC forms a key part of the recently awarded Innovative Medicines Initiative StemBANCC multi-million Euro project led by the University of Oxford.