Establishment of a Muscle Assessment and Training Laboratory at Newcastle University

Lead Research Organisation: Newcastle University

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

Newcastle University were awarded #759K to establish a Muscle Assessment and Training Laboratory. The potential benefits of exercise in ageing, age-related disease and neuromuscular disease are much debated and there has been little progress in translating scientific advances into new treatments. Building on the recent successes in terms of MRC Centres and the NIHR Specialist Biomedical Centre, there is a real opportunity to develop protocols and training regimes that will have direct patient benefit within a short time frame. The initiative would also enable the University to link in with other centres internationally and become a focus of research within the UK.||The MRC Muscle Assessment and Training Laboratory would be central to the success of three major initiatives in Newcastle funded by the MRC and NIHR - Newcastle University Centre for Brain Ageing and Vitality sponsored by BBSRC, EPSRC, ESRC and MRC (Director: Turnbull); MRC Centre for Translational Research in Neuromuscular Disease (co-PI in Newcastle: Turnbull) between Newcastle and London (UCL PI Hanna); NIHR Specialist Biomedical Research Centre for Ageing and Age-related Diseases (Director: Chinnery, Leader on Mitochondria strand; Turnbull).||Newcastle University Centre for Brain Ageing and Vitality sponsored by BBSRC, EPSRC, ESRC and MRC is started in September 2008 and one of the main strands of this major new Centre is to understand the mechanisms by which exercise and diet influence vitality (and prevent frailty). Specifically this will be exploring the mechanisms involved in the protective effect of different forms of exercise on musculoskeletal ageing in terms of physiology, perfusion, mitochondrial function and muscle/joint pathology. This links in with a major initiative to understand the changes that occur in muscle with age and the causes of loss of muscle mass and strength. At least some of these changes are reversed by exercise, but key questions on the best form of exercise (resistance or endurance), whether limitations on the age at which this can be started, effects of such exercise on skeletal and joint ageing are still to be addressed. The MRC Muscle Assessment and Training Laboratory would provide a focus for this research and greatly enhance the Universitys ability to develop protocols which could then be applied widely in the community. This would also link in with related research being developed in the Centre for Brain Ageing and Vitality which is focused on understanding the ways older citizens interact with scientific knowledge about exercise and thus help ensure wide acceptance of best practice.|

Publications

10 25 50

publication icon
Alston CL (2017) The genetics and pathology of mitochondrial disease. in The Journal of pathology

 
Description Capacity building in ageing research
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Influenced training of practitioners or researchers
 
Guideline Title Preventing type 2 diabetes: population and community-level interventions in high-risk groups and the general population
Description Contributions to NICE guidelines for Type 2 diabetes
Geographic Reach National 
Policy Influence Type Citation in clinical guidelines
URL http://www.nice.org.uk/PH35
 
Description DH Physical Activity Taskforce
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description DH Working Group on Physical Activity and Exercise
Geographic Reach National 
Policy Influence Type Participation in advisory committee
 
Description IDF mHealth and diabets global expert working group
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
URL http://www.gsma.com/connectedliving/idf-mou/
 
Description Movement as Medicine: for diabetes
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Movement as Medicine: for your heart
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Influenced training of practitioners or researchers
 
Description NICE Liver Disease guidelines
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
URL https://www.nice.org.uk/guidance/indevelopment/gid-dgwave0692
 
Description NU-AGE undergraduate module
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
Impact As a result of participating in this module, undergraduates from faculties other than the Medical Sciences Faculty have chosen undergraduate degree projects to pursue a PhD in ageing research, The NU-AGE teaching module was shortlisted for a CATE by the Higher Education Academy.
URL http://www.ncl.ac.uk/module-catalogue/module.php?code=AGE2000
 
Description National Writing Group Lead on the Pathway for Physical Activity and Diabetes Research
Geographic Reach Asia 
Policy Influence Type Participation in advisory committee
 
Description Biomedical Research Centre Studentship
Amount £62,849 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 09/2012 
End 08/2015
 
Description Bridging the Urban Divide - UK India initiative
Amount £2,100,000 (GBP)
Organisation Research Councils UK (RCUK) 
Sector Public
Country United Kingdom
Start  
 
Description CASE studentship
Amount £98,180 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start 09/2012 
End 09/2016
 
Description Changing the Physical Activity Landscape (CPAL)/County Durham and Darlington Primary Care Trust
Amount £448,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description County Durham Primary Care Trust
Amount £450,000 (GBP)
Organisation County Durham and Darlington NHS Foundation Trust 
Sector Public
Country United Kingdom
Start  
 
Description County Durham Primary Care Trust: Diabetes Theme/County Durham and Darlington Primary Care Trust
Amount £106,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Diabetes Research Network
Amount £5,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Diabetes UK: PhD studentship
Amount £81,000 (GBP)
Organisation Diabetes UK 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2009 
End 09/2012
 
Description ESRC Knowledge exchange opportunities
Amount £100,473 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 07/2013 
End 06/2014
 
Description European Union Framework Project 7:Liver Disease Call
Amount £420,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description FP7
Amount € 2,500,000 (EUR)
Organisation European Commission 
Department Seventh Framework Programme (FP7)
Sector Public
Country European Union (EU)
Start 01/2012 
End 12/2015
 
Description Industrial CASE Studentship - Philips
Amount £22,482 (GBP)
Organisation Koninklijke Philips Electronics N.V. 
Department Philips
Sector Private
Country Global
Start 10/2013 
End 10/2016
 
Description Industrial CASE studentship - ESRC
Amount £67,443 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2013 
End 10/2016
 
Description Knowledge Transfer Program
Amount £200,000 (GBP)
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start  
 
Description MRC Centre for Neuromuscular Diseases
Amount £957,958 (GBP)
Funding ID MR/K000608/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 02/2013 
End 01/2018
 
Description NIHR Biomedical Research Centre
Amount £101,109 (GBP)
Organisation National Institute for Health Research 
Department NIHR Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 01/2016 
End 03/2017
 
Description NIHR Newcastle Biomedical Research Centre Industry Partnership
Amount £125,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 07/2013 
End 06/2015
 
Description NIHR Senior Investigator
Amount £60,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2009 
End 04/2012
 
Description NIHR Senior Investigator Award
Amount £45,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2015 
End 03/2018
 
Description NIHR Senior Research Fellowship
Amount £989,710 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description NIHR: Biomedical Research Centre for Ageing and Age Related Disease
Amount £32,000 (GBP)
Organisation National Institute for Health Research 
Department NIHR Newcastle Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start  
 
Description NIHR: Flexibility and Sustainability Funding
Amount £276,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Newcastle BRC
Amount £9,000 (GBP)
Organisation National Institute for Health Research 
Department NIHR Newcastle Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 01/2010 
End 12/2010
 
Description Newcastle Hospital Trust: Pump priming/Newcastle Hospitals Trust
Amount £48,415 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description North East Health Innovation and Education Cluster
Amount £100,000 (GBP)
Organisation Newcastle University 
Sector Academic/University
Country United Kingdom
Start  
 
Description RD Lawrence Fellowship
Amount £134,609 (GBP)
Organisation Diabetes UK 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Regional health Innovation and education cluster (Evaluation of the Movement as Medicine pathway in T2 diabetes)
Amount £100,000 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start  
 
Description Understanding the Ageing Heart workshop
Amount £3,000 (GBP)
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Wellcome Trust Centre for Mitochondrial Research
Amount £4,500,000 (GBP)
Funding ID 096919 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2012 
End 04/2017
 
Description adaption to the Movement as Medicine programme
Amount £155,000 (GBP)
Organisation Sport England 
Department County Durham Sport
Sector Private
Country United Kingdom
Start 10/2013 
End 06/2015
 
Title Establishment of the Physical Activity and Exercise Research Group 
Description Funding allowed pump priming for the development of the laboratory and core staff. 
Type Of Material Improvements to research infrastructure 
Year Produced 2009 
Provided To Others? Yes  
Impact Significant increase in physical activity and exercise research. Prior to this program approximately 30 people per year took part in physical activity or exercise research in Newcastle.In 2010 over 400 people took part in physical activity and exercise research across ageing, metabolic and neuromuscular disease. 
 
Title Immunohistochemistry to diagnose mitochondrial disease 
Description Improving the diagnosis of mitochondrial disease in muscle biopsies using a quadruple immunofluorescence technique 
Type Of Material Biological samples 
Year Produced 2015 
Provided To Others? Yes  
Impact This research method has been adopted in our diagnostic protocol. 
 
Title MOVEeCloud 
Description An online open analytical method for the collection and assessment of movement and sleep. 
Type Of Material Improvements to research infrastructure 
Year Produced 2013 
Provided To Others? Yes  
Impact MOVEeCloud is the first scalable secure platform for the collection, sharing and analysis of movement data. It reduces analytical processing time by over 90% and also allows common use of processing techniques. 
URL http://www.moveecloud.com
 
Title Open source Physical Activity monitoring: OpenMovement 
Description Development of the first open platform for physical activity monitoring, data collection and data analysis. 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact We have developed the first open source physical activity monitoring system. The open source pervasive nature of this project will accelerate the use of physical activity monitoring in small and large scale epidemiological and interventional studies. 
 
Title Mito Disease Cohort UK 
Description A database of around 1503 patients with mitochondrial disease, 964 of which were collected in Newcastle. 
Type Of Material Database/Collection of data 
Year Produced 2011 
Provided To Others? No  
Impact All patient data collected is being used to develop clinical guidelines and enrolment in clinical trials. 
 
Description Alere 
Organisation Alere
Country United States 
Sector Private 
PI Contribution Industrial collaborative partner on developing lifestyle interventions
Collaborator Contribution Service development and service delivery
Impact not available
Start Year 2013
 
Description Be Smart, exercise your heart 
Organisation Alzheimer’s Society
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution We are actively collaborating with the Alzheimer's Society on developing and implementing lifestyle service pathways for people at risk of or who have dementia.
Collaborator Contribution The Alzheimer's Society have a wealth of experience working with people with memory problems and their care teams. The Society have been superb in providing insights into care and also assisting with the development of the service pathways and linking with end users and their care teams.
Impact This project is multi disciplinary and is involving service designers, graphic designers, clinical care teams and physiotherapists. We are enhancing existing digital services in a co-design project with and for people with memory problems. These eHealth and mHealth tools will undergo clinical evaluation in 2015.
Start Year 2013
 
Description Boots/Walgreens 
Organisation Boots UK
Country United Kingdom 
Sector Private 
PI Contribution We are exploring the role of pharmacy enhanced services as a way to deliver lifestyle as a clinical service to people wit Type 2 diabetes.
Collaborator Contribution We are leading on focus group work and redesigning our digital health assets to fulfil the needs of Boots. Boots are contributing commercial insight, staff time and access to Boots stores for pilot.feasibility studies.
Impact none yet
Start Year 2014
 
Description Collaboration with University of Calgary 
Organisation University of Calgary
Country Canada 
Sector Academic/University 
PI Contribution Expertise in mitochondrial analysis of muscle and spinal cord
Collaborator Contribution Animal model and expertise in animal exercise physiology
Impact New insights into sarcopenia, multidisciplinary involving clinical, histopathological, molecular genetics and exercise physiology
Start Year 2009
 
Description Collaboration with University of Edinburgh 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Expertise in mitochondrial genetics
Collaborator Contribution Expertise in genetics
Impact Wright AF, Murphy MP, Turnbull DM. Do organellar genomes function as long-term redox damage sensors? Trends Genet 2009; 25: 253-61
Start Year 2008
 
Description Collaboration with University of Texas 
Organisation University of Texas
Country United States 
Sector Academic/University 
PI Contribution Analysis of muscle biopsies from patients undergoing exercise regimes
Collaborator Contribution Exercise physiology
Impact Murphy JL, Blakely EL, Schaefer AM, He L, Wyrick P, Haller RG, Taylor RW, Turnbull DM, Taivassalo T. Resistance training in patients with single, large-scale deletions of mitochondrial DNA. Brain 2008a; 131: 2832-40. Multidisciplinary involving exercise phsyiology, clinical and molecular genetics
Start Year 2007
 
Description County Durham & Darlington Primary Care Trust 
Organisation County Durham and Darlington NHS Foundation Trust
Country United Kingdom 
Sector Public 
PI Contribution Collaborating on the design, evaluation and implementation of a professional development pathway for physical activity in the management of Type 2 diabetes.
Impact This collaboration has led to further collaboration and funding for CVD prevention pathway in primary care. The collaboration also led to further funding from the regional Health Innovation and Education Cluster. The collaboration is multidisaplinary, including; physical activity specialists, health psychologists, diabetologists, physiologists, primary care teams, and designers.
Start Year 2009
 
Description Glasgow University 
Organisation University of Glasgow
Department BHF Glasgow Cardiovascular Research Centre
Country United Kingdom 
Sector Academic/University 
PI Contribution Guidance and input on the non-invasive assessment of muscle and liver lipid.
Collaborator Contribution Brought collaboration on other projects on Type 2 diabetes.
Impact Data currently being collected (statin trial). This is a multi-disaplinary collaboration involving diabetologists, physiologists, clinical trials units, and nutritionists.
Start Year 2009
 
Description Leeds Metropolitan University 
Organisation Leeds Beckett University
Department Carnegie Faculty
Country United Kingdom 
Sector Academic/University 
PI Contribution Input on non-invasive testing of muscle and liver metabolites during exercise.
Impact Data is currently under analysis and will go into peer review in Dec 2010. This collaboration is multi-disaplinary and involves; nutritionists, physiologists and physicists.
Start Year 2009
 
Description Liverpool University CIMA 
Organisation University of Liverpool
Country United Kingdom 
Sector Academic/University 
PI Contribution We are collaborating with Liverpool University as part of the MRC/ARUK Centre for Integrated Musculoskeletal Ageing on a study looking at sedentary behaviour and muscle ageing.
Collaborator Contribution Both sites are contributing clinical facilities and support.
Impact no impact yet
Start Year 2013
 
Description Maastricht University 
Organisation Maastricht University (UM)
Country Netherlands 
Sector Academic/University 
PI Contribution Molecular studies on samples collected in Maastricht
Collaborator Contribution Maastricht provided samples for molecular studies
Impact No outputs yet. This is a multidisciplinary study involving molecular biologists, exercise physiologists and physicians.
Start Year 2011
 
Description NIHR Lifestyle BRU (Leicester) 
Organisation National Institute for Health Research
Department NIHR Biomedical Research Unit, University Hospitals of Leicester NHS Trust
Country United Kingdom 
Sector Public 
PI Contribution Active collaboration on NIHR Senior Fellowship project
Collaborator Contribution Recruitment and delivery of novel analytical methods
Impact none yet
Start Year 2013
 
Description Northumbria University 
Organisation Northumbria University
Department School of Psychology and Sports Science Northumbria
Country United Kingdom 
Sector Academic/University 
PI Contribution Input on exercise testing and non-invasive assessment of muscle and liver metabolite sin athletes.
Impact Publications: 19223653 & 17697427. Work on basic physiology studies to understand the effect of exercise on muscle and liver metabolites. The collaboration is multi-disaplinary and involves nutrition specialists, physicists, and physiologists.
Start Year 2008
 
Description Philips CASE studentship 
Organisation Philips Research
Country United States 
Sector Private 
PI Contribution Working with Philips to explore how technology can be used to help people with memory problems achieve and sustain a physically active lifestyle.
Collaborator Contribution Philips bring a wealth of experience in developing consumer medical products and helping people achieve a more active lifestyle,
Impact This is a multi-disciplinary project involving engineers, designers, physicians and social scientists. The outputs of this collaboration will be finalised in 2015/16.
Start Year 2013
 
Description Sirtris Pharmaceuticals (GSK) 
Organisation Sirtris Pharmaceuticals
Country United States 
Sector Private 
PI Contribution Development of strategic evaluation of drugs which may mimic the effect of exercise.
Impact These studies are ongoing and have no outputs to date. The collaboration is multi-disaplinary and involves physiologists, physiotherapists, neurologists, molecular biologists and physicists.
Start Year 2009
 
Description Unilever - Physical activity monitoring platform 
Organisation Unilever
Country United Kingdom 
Sector Private 
PI Contribution One of the senior postdoctoral researchers is ocordinating the physicial activity monitoring platform.
Collaborator Contribution This is a joint project
Impact Joint project grant. This is a multidisciplinary project involving designers, software engineers, physiologists, physicians, physiotherapists and signal processors.
Start Year 2011
 
Title System for the self-monitoring and regulation of blood glucose 
Description Linking the detection of increasing blood glucose with physical activity 
IP Reference WO2012123765 
Protection Patent application published
Year Protection Granted 2013
Licensed No
Impact None yet - part of current industrial collaboration award
 
Title MOVEeCloud 
Description This is a cloud-internet based physical activity, function and sleep analysis platform developed in collaboration with the RCUK Social Inclusion through the Digital Economy hub in Newcastle. 
Type Support Tool - For Fundamental Research
Current Stage Of Development Refinement. Non-clinical
Year Development Stage Completed 2011
Development Status Under active development/distribution
Impact none yet 
 
Title Movement as Medicine 
Description The UK's first professional and patient development pathway for physical activity in the care of Type 2 diabetes. 
Type Therapeutic Intervention - Physical
Current Stage Of Development Initial development
Year Development Stage Completed 2011
Development Status Under active development/distribution
Impact not known 
 
Title Movement as Medicine for Cardiovascular Disease 
Description Clinical trial currently underway 
Type Therapeutic Intervention - Psychological/Behavioural
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2014
Development Status Under active development/distribution
Clinical Trial? Yes
Impact Still under development 
URL http://www.movemedicine.co.uk
 
Title Movement as Medicine for Type 2 diabetes 
Description A cluster-based randomised controlled trial to assess feasibility, acceptability and effectiveness of a multi-faceted behavioural intervention targeting levels of physical activity in adults with Type 2 diabetes in primary care: Movement as Medicine for Type 2 diabetes. 
Type Preventative Intervention - Behavioural risk modification
Current Stage Of Development Initial development
Year Development Stage Completed 2013
Development Status Under active development/distribution
Clinical Trial? Yes
Impact This trial has just finished and will yield results early next year 
URL http://www.movemedicine.com
 
Title Movement as Medicine for CVD 
Description Online learning programme for people at risk of CVD and their care teams. 
Type Of Technology Webtool/Application 
Year Produced 2014 
Impact Currently undergoing clinical trial. 
URL http://www.movemedicine.co.uk
 
Title Movement as Medicine for Type 2 diabetes 
Description An online learning programme for diabetes care teams 
Type Of Technology Webtool/Application 
Year Produced 2014 
Impact This training platform has undergone clinical trial and will be made publicly available in 2015. 
URL http://www.movemedicine.com
 
Description ABN 2015 Harrogate 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited speaker at the Annual Meeting of the Association of British Neurologists 2015 in Harrogate
Year(s) Of Engagement Activity 2015
URL http://www.theabn.org/news/abn-annual-meeting-2015.html
 
Description Autumn meeting of the Association of British Neurologists 2015 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited speaker at the Autumn 2015 meeting of the ABN in London.
Year(s) Of Engagement Activity 2015
URL http://www.theabn.org/media/2015%20London%20ABN%20programme%20final%2024%20June%202015.pdf
 
Description British Science Festival 2013 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Schools
Results and Impact We led an interactive workshop for the public on ageing and lifestyle.

Public awareness of science and engaging children in science.
Year(s) Of Engagement Activity 2013
URL http://www.britishscienceassociation.org/british-science-festival/newcastle-2013
 
Description DUK National Patient Engagement Day 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Type Of Presentation Keynote/Invited Speaker
Geographic Reach Regional
Primary Audience Participants in your research and patient groups
Results and Impact Talk entitled, 'Standing up for Type 2 diabetes' to the Diabetes UK National Patient Engagement Day in June 2012

not known
Year(s) Of Engagement Activity 2012
 
Description Diabetes UK Patient Group: Darlington 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Participants in your research and patient groups
Results and Impact 30 Patients with type 2 diabetes; lots of discussion on diabetes management and impact of physical activity.

Patient questions and improved understanding of physical activity and diabetes
Year(s) Of Engagement Activity 2010
 
Description Diabetes UK Patient Group: Newcastle 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Participants in your research and patient groups
Results and Impact 30 Patients with type 2 diabetes attended: discussion on diabetes and physical activity.

Improved knowledge of diabetes and physical activity
Year(s) Of Engagement Activity 2010
 
Description Diabetes UK Patient Group: North Tyneside 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Participants in your research and patient groups
Results and Impact 30 Patients with type 2 diabetes; discussed diabetes and the role of physical activity

Improved knowledge of diabetes and the role of physical activity.
Year(s) Of Engagement Activity 2009
 
Description Diabetes UK Patient Group: Tynedale 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Participants in your research and patient groups
Results and Impact 30 Patients with type 2 diabetes: discussion of diabetes and the role of physical activity

Improved knowledge of diabetes and physical activity.
Year(s) Of Engagement Activity 2010
 
Description Diabetes UK Science and Research Advisory Board 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact members of the Diabetes UK working group setting the scientific direction of research undertaken by DUK.

Links with Diabetes UK and other researchers as well as influencing research direction across the UK.
Year(s) Of Engagement Activity 2013
 
Description Diabetes UK: Meet the Professors 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Participants in your research and patient groups
Results and Impact 90 People with type 2 diabetes and 20 care professionals; discussion on diabetes and teh role of physical activity.

Improved knowledge of diabetes and the role of physical activity.
Year(s) Of Engagement Activity 2009
 
Description Engage Conference Bristol 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The Engage conferences are aimed at Universities and are designed to help researchers find better ways of involving people from outside academia in conceiving, shaping, producing and applying powerful research?
Year(s) Of Engagement Activity 2015
URL https://www.publicengagement.ac.uk/events/engage-conference-2015
 
Description Fit as a Falcon 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact An activity day attended by over 100 school children showcasing the four themes of the Centre. The day was organised in collaboration with Newcastle Falcons Community Foundation and built on work they were already doing with schools in the area. The activities were designed to show how a healthy lifestyle when we are younger affects the way we age, focusing on exercise and nutrition.
Feedback from the children, teachers and students and scientists involved in the event was very positive. It also worked well from the Falcons perspective and they have asked us to make this an annual event. There will also be opportunities to be involved with other engagement programmes that the Falcons Community foundation are running.
Year(s) Of Engagement Activity 2016
 
Description IDF mHealth Expert Working Group 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Member of the IDF Expert working group on mHealth developing policy advice on mobile technologies and their role in diabetes in partnership with the global mobile phone representative body (GSMA).

Links wit policy forming groups and industry
Year(s) Of Engagement Activity 2013
URL http://www.idf.org
 
Description Keeping active matters 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Engagement event on the benefits of physical activity for members of our Voice North panel and members of the public. Researchers gave talks during a number of interactive sessions.

not yet known
Year(s) Of Engagement Activity 2014
 
Description Led mHealth Tour 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Participants in your research and patient groups
Results and Impact I led the world's first mHealth bike ride from Brussels to Barcelona to raise awareness of type 1 diabetes and the role of technology

connection with patients and companies involved in digital health and diabetes
Year(s) Of Engagement Activity 2013
URL http://www.mhealthtour.com
 
Description MEdia: Granada TV 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact ITV Documentary on "Exercise and the elderly"

Regional discussion of the role of exercise in the elderly.
Year(s) Of Engagement Activity 2008
 
Description Media: Channel 4 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Dispatched documentary on "Dispelling the myths of Ageing"

National discussion of what ageing is and how to age well.
Year(s) Of Engagement Activity 2009
 
Description Mini Medical School for Older People 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact 50 people attended a workshop at the Newcastle University Centre for Life.

Gave an insight into what research is happening in Newcastle and how the medical profession is involved in research.
Year(s) Of Engagement Activity 2011
 
Description Mini-Medical School: Public Lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact 90 pupils who wished to do medicine at university attended; two presentation with interactive discussion.

Provide insight into the work which medical researchers and the medical profession do.
Year(s) Of Engagement Activity 2010
 
Description Move Like A Pro 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Move Like A Pro is a 12-week programme funded by Premiership Rugby and Movember to encourage middle-aged men who are not particularly active to adopt a healthier lifestyle. One of our researchers presented her research on how being active affects healthy ageing to the group towards the end of the programme. The talk was well received and we have been asked to provide input to future rounds of the programme
Year(s) Of Engagement Activity 2016
URL https://movelikeapro.co.uk/
 
Description NE Physical Activity Forum 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Health professionals
Results and Impact Led a workshop module on physical activity and obesity.

Improved networking and academic - clinical service links.
Year(s) Of Engagement Activity 2009
 
Description NIHR Ageing Biomedical REsearch Centre lectures 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact One of 6 keynote lectures on ageing to a nationally representative group

Links with other groups and raised awareness of ageing research.
Year(s) Of Engagement Activity 2013
 
Description National Obesity Forum 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Health professionals
Results and Impact 50 health professionals specialising in obesity management.

Networking - improved links between clinical practice and academics.
Year(s) Of Engagement Activity 2010
 
Description National Writing Group on Physical Activity and Diabetes 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Health professionals
Results and Impact 10 clinical leads from UK institutions met to arrange the national direction of physical activiity research in Type 2 diabetes.

Definition of a national pathway for physical activity and diabetes research.
Year(s) Of Engagement Activity 2010
 
Description Newcastle Diabetes UK voluntary group 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Participants in your research and patient groups
Results and Impact Over 40 people belonging to the Diabetes UK patient group attended a lecture about physical activity. There was a lengthy question and answer session and a good deal of discussion afterwards.

Provided information to people about how physical activity can be used as an effective 'medicine' to treat diabetes.
Year(s) Of Engagement Activity 2011
 
Description Newcastle Science Festival 2010 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presented a poster entitled, "Should you put all your eggs in one basket? Fitting another piece to the Parkinson's disease puzzle." Attendees asked questions and discussed the findings.

not known
Year(s) Of Engagement Activity 2010
 
Description Newcastle University engagement activities 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The Centre continues to provide funding towards the salary of Newcastle University's Public Engagement Team. The University has a broad programme of engagement activities. Over the last 12 months there have been over 15 events aimed at disseminating the University's research and activity to the general public. They communicate the activities of CBAV on a monthly basis through Voice North (the Regional Engagement Panel made up of a group of over 700 people reflecting the ag- structure and geographical and socioeconomic make-up of the North East) communications and events and through Years Ahead, the North East Regional Forum on Ageing.

The activities of the public engagement team raise awareness of the research being undertaken by the Centre and the University as a whole. Voice North provides focus groups which contribute to the development of research projects and provide participants for research projects.
Year(s) Of Engagement Activity 2008,2009,2010,2011
 
Description Presentation to Peers in the Houses of Parliament 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Discussion with peers at the Houses of Parliament prior to the vote on changing the law to allow mitochondrial donation.
Year(s) Of Engagement Activity 2015
 
Description Press release: Walking and Type 2 diabetes 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Press release on physical activity research on diabetes: 27 mainstream papers worldwide, over 100 websites, and regional radio/television.

Promoted discussion of the role of walking in the management of type 2 diabetes.
Year(s) Of Engagement Activity 2008
 
Description Progress Educational Trust meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Talk at the PET annual confrence. The 2015 annual conference of the Progress Educational Trust (PET) focused on the advent of new methods of making enduring changes to the human embryo - changes that, if used in treatment, will affect not only the person born but also subsequent generations.
Year(s) Of Engagement Activity 2015
URL http://www.progress.org.uk/conference2015
 
Description Response to Science comment article on mitochondrial transfer 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact The article on the mitochondrial transfer technique sparked a media frenzy with articles appearing in many newspapers and magazines worldwide as well as extensive coverage on TV, radio and the internet. Below is a selection of items.
http://www.sciencemediacentre.org/tag/mitochondrialdna/
http://theconversation.com/viewpoints-the-promise-and-perils-of-three-parent-ivf-18402
http://www.bbc.co.uk/news/health-24158049
BBC News (quotes Robin LovellBadge and Doug Turnbull)
http://www.bbc.co.uk/news/health24158049
New Scientist (quotes Doug Turnbull)
http://www.newscientist.com/article/dn24230warningsoundedoverthreeparentivfsafety.
html#.UjwUrz82nm4
Times (quotes Robin LovellBadge and Doug Turnbull)
http://www.thetimes.co.uk/tto/health/news/article3874038.ece
Science AAAS (quotes Robin LovellBadge)
http://news.sciencemag.org/biology/2013/09/newcontroversyoverexperimentalivfmethod
BBC News (quotes Robin LovellBadge and Doug Turnbull)
http://www.bbc.co.uk/news/health24158049


The extensive media coverage has increased awareness of mitochondrial disease and we have received an increased number of enquiries and hits on our website.
Year(s) Of Engagement Activity 2014
 
Description School Visit: Hayden Bridge 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Led problem based learning workshops on obesity and the role of physical activity. 6th form pupils.

Improved awareness of the clinical impact of obesity and the potential role of physical activity.
Year(s) Of Engagement Activity 2009
 
Description School visit: Haydon Bridge 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Open day on physiological measurement in obesity and metabolism; pupils got hands on experience of techniques discussed in their A-levels.

Improved knowledge of techniques: de-geeking science.
Year(s) Of Engagement Activity 2009
 
Description Science on a Plate 2013 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Schools open day of lectures and interactive tasks

Links with schools and motivating the next generation of scientists.
Year(s) Of Engagement Activity 2013
 
Description Science on a Plate workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Type Of Presentation Workshop Facilitator
Geographic Reach Regional
Primary Audience Schools
Results and Impact Two researchers from Newcastle MoveLab led a workshop for young people entitled, "which is more important - fitness or fatness?". They provided thought provoking information, such as, "why watching television can cause diabetes," and "why bus driving is bad for your heart." The workshop participants helped with a fully monitored exercise test, ECG monitoring and real time analysis of respiraiton.

not yet known
Year(s) Of Engagement Activity 2012
 
Description Society for Endocrinology conference 2015 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited speaker at the annual Society for Endocrinology Conference in Cologne,Germany.
Year(s) Of Engagement Activity 2015
URL http://Cecad.uni-koeln.de
 
Description Which is more important - fitness or fatness? 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Schools
Results and Impact Children from three local secondary schools attended the workshop and participated fully in the discussions. They also helped with a fully monitored exercise test, ECG monitoring and real time analysis of respiration.

not yet known
Year(s) Of Engagement Activity 2013
 
Description institute of Education London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited speaker at the Institute of Education London on 10 September 2015
Year(s) Of Engagement Activity 2015
 
Description mHealth Cycle Grand Tour Demonstration 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact The MoveLab team set up a cycle demonstration in the student forum at Newcastle University and linked to a screen to stream coverage from the mHealth Cycle Grand Tour.

Raised awareness of diabetes and the potential power of mHealth solutions.
Year(s) Of Engagement Activity 2013
URL http://www.ncl.ac.uk/press.office/press.release/item/pedalling-towards-better-diabetes-management#hp...
 
Description mHealth lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact keynote lecture on mHealth solutions and data from recent mHealth tour

Connections with policymakers and healthcare providers.
Year(s) Of Engagement Activity 2013
URL http://www.idf.org/worlddiabetescongress