Biomedical Catalyst – Demonstration of a low cost implantable blood pump

Lead Research Organisation: Swansea University


Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.


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Pieper IL (2016) Quantification methods for human and large animal leukocytes using DNA dyes by flow cytometry. in Cytometry. Part A : the journal of the International Society for Analytical Cytology

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Radley G (2018) The effect of ventricular assist device-associated biomaterials on human blood leukocytes. in Journal of biomedical materials research. Part B, Applied biomaterials

Title Research as Art 
Description Public engagement activity with local primary school to create artwork entry for Research as Art at Swansea University 
Type Of Art Artwork 
Year Produced 2018 
Impact Enthusiasm to engage in this type of activity again for myself and to encourage my research team to do so. 
Description HCRW pathway to portfolio
Amount £19,540 (GBP)
Organisation Health and Care Research Wales 
Sector Public
Country United Kingdom
Start 04/2019 
End 10/2019
Description Impact Acceleration Account
Amount £2,157 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 03/2016 
End 12/2016
Description Seed corn grants
Amount £2,981 (GBP)
Organisation St. David's Medical Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2014 
End 09/2015
Title Modeling shear and biomaterial exposures in humans 
Description In vitro model for exposing small volumes of human blood to different biomaterials and a fluid shear regime 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2018 
Provided To Others? Yes  
Impact Invitation to join multi-national consortium developing a total artificial heart. 
Description Erasumus+ Staff Mobility 
Organisation Heart and Diabetes Centre North Rhine-Westphalia (HDZ NRW)
Country Germany 
Sector Hospitals 
PI Contribution Dr Pieper, the post-doctoral researcher on the project has been awarded an Erasmus+ staff mobility award to travel to Professor Hendrik Milting's laboratory and undertake training as a prelude to exchange of samples and methodologies.
Collaborator Contribution The partners will provide some training but also plasma samples from patients who have been implanted with ventricular assist devices, and explanted devices.
Impact This collaboation is in its early stages but we are targeting Horizon 2020 submission in 2015.
Start Year 2014
Description Hybrid Heart 
Organisation University of Amsterdam
Country Netherlands 
Sector Academic/University 
PI Contribution Swansea University is a partner on a short-listed BHF Big Beat Challenge grant contributing to one work package related to in vitro testing with human blood. This involvement is a direct outcome of the Biomedical Catalyst award.
Collaborator Contribution This multi-national consortium is led from Amsterdam University Medical Centre
Impact This collaboration is in its early stages; unsuccessful application to BHF Big Beat Challenge but exploring other opportunities.
Start Year 2019
Description Optimised assay development for blood health in transfusion settings 
Organisation Haemair Ltd
Country United Kingdom 
Sector Private 
PI Contribution We have developed a red blood cell fragility assay for flow cytometry which is now in use by the company; we are progressing to cytokine assays of fluid phase.
Collaborator Contribution The company provides the devices for testing, staff to run the assays once developed, and undertake all experimental work and data analysis
Impact A grant application to SMARTExpertise, Welsh Government (SMARTBlood)is in preparation
Start Year 2016
Description Scandinavian Real Heart 
Organisation Scandinavian Real Heart AB
Country Sweden 
Sector Private 
PI Contribution Insight into mechanisms, implementation of rig tests, access to patients and their samples, laboratory analysis, publications, seeking grant funding
Collaborator Contribution This is in preparation - specific testing rig and computational modelling insight.
Impact Ww have submitted an outline project grant application to NC3Rs which as been invited to full application
Start Year 2018
Description SoapBox Science 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Participated in SoapBox Science, Swansea
Year(s) Of Engagement Activity 2015