UoC Confidence in Concept 2013

Lead Research Organisation: University of Cambridge

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding.  It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.

Publications

10 25 50
 
Description AZ Studentship
Amount £128,000 (GBP)
Organisation AstraZeneca 
Sector Private
Country United Kingdom
Start 01/2016 
End 05/2019
 
Description An advanced cryoEM instrument for the University of Cambridge
Amount £3,000,000 (GBP)
Funding ID 206171/Z/17/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2017 
End 01/2022
 
Description An electron cryo-microscopy resource for macromolecular structure determination in the University of Cambridge
Amount £1,000,000 (GBP)
Funding ID 202905/Z/16/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2016 
End 12/2021
 
Description CRUK Multidisciplinary Project Award
Amount £475,000 (GBP)
Organisation Cancer Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2016 
End 04/2019
 
Description Framework s'ship: structural and functional studies of the machinery of bacterial riboregulation
Amount £122,390 (GBP)
Organisation AstraZeneca 
Sector Private
Country United Kingdom
Start 10/2016 
End 09/2020
 
Description GSK Innovation Funding Opportunity
Amount £323,037 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start 12/2014 
End 12/2016
 
Description Pioneer Award
Amount £200,000 (GBP)
Organisation Cancer Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2016 
End 03/2018
 
Description Programme grant
Amount £1,000,000 (GBP)
Organisation University of Cambridge 
Department MRC Cancer Unit
Sector Public
Country United Kingdom
Start 09/2016 
End 08/2019
 
Description WD Armstrong Studentship
Amount £63,000 (GBP)
Organisation University of Cambridge 
Department WD Amstrong Trust
Sector Academic/University
Country Unknown
Start 10/2015 
End 10/2018
 
Description WT Pathfinder
Amount £140,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2014 
End 12/2015
 
Description Wellcome Trust Translation Award Concept
Amount £140,392 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2015 
End 09/2016
 
Title "NC-IUPHAR" is the International Union of Basic and Clinical Pharmacology Database; Anthony Davenport, UK - Executive Member of NC-IUPHAR - EAB Liaison with NC-IUPHAR 
Description "NC-IUPHAR" is the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification. The mission for NC-IUPHAR was initiated in 1987 at the Xth International Congress of Pharmacology. 
Type Of Material Database/Collection of data 
Provided To Others? Yes  
Impact The British Journal of Pharmacology and its publisher Wiley have been publishing articles for some time. You can see examples both in the CGTP 2013/14 series (https://www.ncbi.nlm.nih.gov/pubmed/?term=Concise%5bTitle%5d%20AND%20Guide%5bTitle%5d%20AND%20PHARMACOLOGY%5bTitle%5d&cmd=DetailsSearch) and recent NC-IUPHAR reviews (e.g. this 2014 one on epigenetic pathways) 
URL http://www.guidetopharmacology.org/
 
Title PATIENT-SPECIFIC ENDOVASCULAR DEVICES 
Description Methods for manufacturing a patient-specific endovascular device comprise creating a 3D model based on spatial dimensions relating to a section of a blood vessel and manufacturing the endovascular device using the 3D model to form a liner. In use the endovascular devices provide a liner which forms a seal against the inner blood vessel wall or the edge of the blood flow lumen. Corresponding patient-specific endovascular devices and methods for treating a patient by inserting an endovascular device are also provided. 
IP Reference WO2017187174 
Protection Patent granted
Year Protection Granted 2017
Licensed No
Impact Not yet
 
Description Cambridge News article "Scientists box clever, as 'Soapbox Science' roadshow comes to Cambridge" 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact "Scientists box clever, as 'Soapbox Science' roadshow comes to Cambridge"
Year(s) Of Engagement Activity 2016
 
Description 'Infectious disease in the 21st Century' 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Prof Lever presented two public lectures in which the work was mentioned- 'Infectious disease in the 21st Century', at Addenbrookes Hospital and Peterhouse College
Year(s) Of Engagement Activity 2017
 
Description Cambridge News article: "Cambridge University researchers developing tiny optical-fibre endoscope to aid doctors" 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact "Cambridge University researchers developing tiny optical-fibre endoscope to aid doctors"
Year(s) Of Engagement Activity 2015
 
Description Cambridge News article: "New research programme in Cambridge could help detect cancer earlier" 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact "New research programme in Cambridge could help detect cancer earlier"
Year(s) Of Engagement Activity 2015
 
Description Krishnaa Mahbubani participated as a week of outreach programmes and is currently a careers zone advisor on I'm an Engineer Get Me Out of Here, discussing the interesting facts and challenges faced in cryobiology and cryoengineering. 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Krishnaa Mahbubani participated as a week of outreach programmes and is currently a careers zone advisor on I'm an Engineer Get Me Out of Here, discussing the interesting facts and challenges faced in cryobiology and cryoengineering.
Year(s) Of Engagement Activity 2016
 
Description Krishnaa Mahbubani: a Governor for the Society of Cryobiology 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Krishnaa Mahbubani has been nominated to stand as a Governor for the Society of Cryobiology as an outcome of research presentations and further discussions within the field.
Year(s) Of Engagement Activity 2016
 
Description Publication of Waterhouse et al manuscript featured on BBC and Financial Times online, as well as numerous trade news outlets 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Publication of Waterhouse et al manuscript featured on BBC and Financial Times online, as well as numerous trade news outlets (2016)
Year(s) Of Engagement Activity 2016
 
Description Validation of genomic RNA packaging as a therapeutic target for HIV/AIDS 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact The work has also been presented by both Prof Lever and Dr Kenyon at a range of University outreach events to a total of around 350 sixth form students interested in studying science at University.
Year(s) Of Engagement Activity 2017
 
Description Validation of genomic RNA packaging as a therapeutic target for HIV/AIDS 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact The general work was presented to a lay audience via an article in 'the Homertonian' magazine, which is mailed in hard copy to 13,325 subscribers and publicly available online (https://issuu.com/homerton/docs/homertonian_2016_-_number_20 ). Many of the readers are current secondary school teachers.
Year(s) Of Engagement Activity 2016