ICL Confidence in Concept 2013

Lead Research Organisation: Imperial College London

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding.  It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.

Publications

10 25 50
 
Description Turner - ICiC2 - Joint Committee on Vaccination and Immunisation (JCVI)
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Asked to advise the Joint Committee on Vaccination and Immunisation (JCVI) which advises UK health departments on immunisation relating to influenza.
URL https://www.gov.uk/government/publications/influenza-the-green-book-chapter-19
 
Description Apollo Therapeutics Award
Amount £280,000 (GBP)
Organisation Apollo Therapeutics 
Sector Private
Country United Kingdom
Start 03/2018 
End 10/2018
 
Description Apollo Therapeutics Award
Amount £539,000 (GBP)
Organisation Apollo Therapeutics 
Sector Private
Country United Kingdom
Start 03/2017 
End 09/2017
 
Description BHF Project Grant
Amount £296,000 (GBP)
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start 12/2015 
End 11/2018
 
Description Basic Research Capability Enhancement Program
Amount £18,392 (GBP)
Organisation National Research Foundation of Korea 
Sector Academic/University
Country Korea, Republic of
Start 09/2015 
End 08/2016
 
Description CASE PhD Award
Amount £106,564 (GBP)
Funding ID MR/N017757/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2017 
End 03/2021
 
Description Confidence in Concept
Amount £840,000 (GBP)
Funding ID MC_PC_16046 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2017 
End 02/2019
 
Description Confidence in Concept
Amount £944,000 (GBP)
Funding ID MC_PC_17162 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2018 
End 02/2020
 
Description Confidence in Concept 3
Amount £800,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2015 
End 09/2016
 
Description Confidence in Concept 4
Amount £900,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2016 
End 02/2018
 
Description Developmental Pathway Funding Scheme
Amount £650,810 (GBP)
Funding ID MR/N027736/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 07/2016 
End 07/2018
 
Description Dickinson - ICiC 2 - MRC DPFS
Amount £651,000 (GBP)
Funding ID MR/N027736/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Edwards - ICiC 2 - WT PS
Amount £125,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Fuchter - ICiC 2 - IBCOMP
Amount $226,000 (USD)
Organisation Michael J Fox Foundation 
Sector Charity/Non Profit
Country United States
Start  
 
Description Imperial Innovations Proof of Concept Grant
Amount £20,000 (GBP)
Organisation Imperial Innovations 
Sector Private
Country United Kingdom
Start 02/2016 
End 05/2016
 
Description Improved Biomarkers & Clinical Outcome Measures RFA - Michael J Fox Foundation
Amount $226,000 (USD)
Organisation Michael J Fox Foundation 
Sector Charity/Non Profit
Country United States
Start 01/2016 
End 03/2017
 
Description MRC DPFS
Amount £286,000 (GBP)
Funding ID MR/M025004/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 07/2015 
End 12/2016
 
Description NHLI Independent Research Fellowship
Amount £20,000 (GBP)
Organisation Imperial College London 
Department National Heart & Lung Institute (NHLI)
Sector Academic/University
Country United Kingdom
Start 08/2015 
End 07/2016
 
Description Pathfinder
Amount £125,000 (GBP)
Funding ID 204337/Z/16/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2017 
End 09/2018
 
Description Royal Brompton & Harefield NHS Foundation Trust Seed Funding
Amount £19,010 (GBP)
Organisation Royal Brompton & Harefield NHS Foundation Trust 
Sector Public
Country United Kingdom
Start  
 
Description Senior Research Fellowship
Amount £1,667,327 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2018 
End 02/2023
 
Description Snelgrove - ICiC 2 - AUKIA
Amount £46,500 (GBP)
Funding ID AUK-IG-2014-286 
Organisation Asthma UK 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2014 
End 03/2016
 
Description Snelgrove - ICiC 2 - VIPA
Amount £85,200 (GBP)
Organisation Wellcome Value in People Award 
Sector Academic/University
Country United Kingdom
Start 10/2016 
End 10/2017
 
Description UK-India Educational Research Initiative
Amount £78,000 (GBP)
Organisation British Council 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2017 
End 04/2020
 
Description Wellcome Trust Enhancement Grant
Amount £100,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2015 
End 10/2017
 
Description Wellcome Trust Pathfinder Award
Amount £108,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2015 
End 08/2016
 
Title Baum - ICiC2 - Method for high throughput screening for potential inhibitors of malaria parasite (Plasmodium falciparum) protein translation in vitro 
Description We have developed a cell free protein translation assay and optimised this to 384 well plate (and validated it) to screen for potential drugs that inhibit protein translation. The assay was validated with both known and unknown drugs. The assay is based on 384 well plate and use of a spectrofluorometer, detecting luminescence from a luciferase-derived protein, expression by a parasite cell free lysate. 
Type Of Material Technology assay or reagent 
Provided To Others? No  
Impact We are hoping this tool will enable us to source funding to undertake high throughput screening of novel antimalarials in collaboration with the University of Dundee. 
 
Title Baum - ICiC2 - Translation-Inhibition 
Description The program aimed to develop a drug screening assay based on a method of processing parasite lysate into an in vitro competent expression system that can then be used in a plate based (high throughput) screening assay, monitoring for fluorescence/luminescence. 
Type Of Material Technology assay or reagent 
Year Produced 2016 
Provided To Others? Yes  
Impact Once developed the assay platform will provide a means to screen libraries of drugs for potential antimalarials that target protein translation. 
 
Title Cass - ICiC2 - Nanostars 
Description Gold/silver nanostars are excellent structures for performing surfaced enhanced Raman spectroscopy (SERS). The method involves coating polymer microprobe structures, originally designed for minimally invasive continuous glucose sensing, with the nanostars and using these for minimally invasive sensing of other metabolites in the interstitial fluid by SERS. For additional specificity and sensitivity the nanostars can be modified with aptamers 
Type Of Material Technology assay or reagent 
Provided To Others? No  
Impact This tool is still being developed and has not yet generated any published or otherwise reported impacts. 
 
Title Peters - ICiC2 - AFWT 
Description Matlab code developed to analyse electroanatomic mapping data from patients in atrial fibrillation undergoing cardiac ablation. It computes the phase of the signal to identify activations of significantly varying amplitude, windows the signal and computes wavefront trajectories across the mapping area so as to identify the nature of propagation and direction of originating source. 
Type Of Material Physiological assessment or outcome measure 
Provided To Others? No  
Impact None as yet 
 
Description Baum - ICiC2 - GlaxoSmithKline (GSK) 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution Our lab is developing the in vitro drug screening assay, validating its activity and then taking this to GSK to enable miniaturisation required for high throughput drug screening of libraries.
Collaborator Contribution GSK is providing in-house expertise and resources for the miniaturisation of our assay (once completed) towards making it industry standard for screening. This will take the form of a short term (6 weeks to 2 months) visit by Dr. Hella Baumann from the Baum lab who will work with GSK scientists to complete the miniaturisation of the assay.
Impact The collaboration involves parasitology (parasite culture), biochemistry (in vitro translation) and high throughput screening. At present there have been no outputs to report (it is still an active collaboration). No published papers or meeting abstracts.
Start Year 2015
 
Description Cass - ICiC2 - PNG 
Organisation University of Glasgow
Department School of Engineering Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution We designed the microprobe structures and had the necessary dies machined.
Collaborator Contribution Prof Gadegaard then used the dies to injection mould the microprobes in poly(carbonate) producing replica structures
Impact The first description was submitted as an abstract for Biosensors 2016 and will be presented as a poster at the conference in May this year. The injection moulded structures are also being used in the next phase of a NIHR funded clinical studies. Disciplines are: Chemistry, materials science, biomedical engineering
Start Year 2015
 
Description Dickinson - ICiC2 - Mainz 
Organisation Johannes Gutenberg University of Mainz
Country Germany 
Sector Academic/University 
PI Contribution Sharing of knowledge and techniques on brain injury models & neuroprotection
Collaborator Contribution Sharing of knowledge and techniques on brain injury models & neuroprotection. This collaboration was initiated prior to the ICiC award but is important to Dr Dickinson's ICiC2 project.
Impact Crit Care Med. 2015 Jan;43(1):149-58. doi: 10.1097/CCM.0000000000000624. Xenon improves neurologic outcome and reduces secondary injury following trauma in an in vivo model of traumatic brain injury. Campos-Pires R1, Armstrong SP, Sebastiani A, Luh C, Gruss M, Radyushkin K, Hirnet T, Werner C, Engelhard K, Franks NP, Thal SC, Dickinson R BNA Meeting Edinburgh April 2015 Poster Xenon provides short term & long term neuroprotection in an in vivo model of traumatic brain Injury Rita Campos-Pires, Scott Armstrong, Anne Sebastiani, Tobi Hirnet, Clara Luh, Konstantin Radyushkin, Serge Thal, Nicholas Franks, Robert Dickinson Mechanisms of Anaesthesia Conference, Bonn Germany June 17th 2015: Oral presentation Rita Campos-Pires Xenon provides short term & long term neuroprotection in an in vivo model of traumatic brain
Start Year 2010
 
Description Elson - ICiC 2 - DKFZ 
Organisation German Cancer Research Center
Country Germany 
Sector Public 
PI Contribution Fabrication of structured lighting system with hyperspectral imaging for data acquisition in vitro and in vivo.
Collaborator Contribution Discussion of technical ideas for processing and evaluation of structured lighting data.
Impact Conference paper submitted to MICCAI 2017.
Start Year 2016
 
Description Gunn - ICiC2 - DBG & DJM 
Organisation Imperial College London
Department Department of Computing
Country United Kingdom 
Sector Academic/University 
PI Contribution Prof Gunn's group including Dr Philip Noonan (Department of Medicine) implemented and evaluated GEM software modified to use multiple Kinect v2 sensors for increased field of view motion tracking in a PET/CT scanner.
Collaborator Contribution Dr Ben Glocker + Dr. Jiefei Ma (Department of Computing) developed the GEM software for augmented reality applications. They assisted in 3D printing phantoms used to enable successful stereo calibration of the Kinect sensors.
Impact An oral presentation at the IEEE Medical Imaging Conference in San Diego with associated conference proceedings to be published. This collaboration involved computer sciences with medical physics and engineering.
Start Year 2015
 
Description Moore - ICiC2 - Early node implant trial in Belgium 
Organisation Catholic University of Louvain
Country Belgium 
Sector Academic/University 
PI Contribution All background work of implant design and manufacturing.
Collaborator Contribution Operational plans for implant procedures.
Impact None yet - too early
Start Year 2015
 
Description Peters - ICiC2 - SJM 
Organisation St. Jude Medical
Country United States 
Sector Private 
PI Contribution St. Jude Medical provide us with access to their systems and code to work with clinical data acquired for our R&D purposes, from which our technical insights support both our thoughts and IP, and help with their understanding the needs of clinicians in front-line cardiac arrhythmia treatment.
Collaborator Contribution St Jude Medical are a company (based in Boston, USA) who develop electroanatomic mapping systems for use in cardiac ablation therapy. In particular, they develop the EnSite Velocity mapping system currently used for a significant proportion of atrial catheter ablation cases at Hammersmith Hospital. For this project they provide early access to new commercial products and technical advice on their use. They also provide exclusive or limited access to some research-related technologies. The collaboration began prior to the ICiC award but is important in Prof Peters' ICiC2 project
Impact None so far
 
Description Snelgrove - ICiC1+2 - DrSH 
Organisation Imperial College London
Department Department of Life Sciences
Country United Kingdom 
Sector Academic/University 
PI Contribution Generation / provision of novel Leukotriene A4 hydrolase (LTA4H) modulators and recombinant LTA4H enzyme. Knowledge of LTA4H active site and Structure-Activity Relationship (SAR) studies.
Collaborator Contribution Expertise in X-ray crystallography - conducted experiments and analysis.
Impact Successful generation of X-ray crystallography structures of lead compounds bound within active site of LTA4H. These will form part of a manuscript currently in preparation. They were also part of an unsuccessful application to the Wellcome Trust seeding drug discovery scheme and will form part of an application to the MRC DPFS scheme.
Start Year 2014
 
Description Snelgrove - ICiC1+2 - ProfCL 
Organisation Imperial College London
Department National Heart & Lung Institute (NHLI)
Country United Kingdom 
Sector Academic/University 
PI Contribution We have utilised Professor Lloyd's models of allergic airways disease to test our LTA4H knock-out mice and LTA4H modulators. We conducted all experiments and analysis with some technical help from Professor Lloyd's group,
Collaborator Contribution Professor Lloyd is a world leader in murine models of allergic airways disease. She has provided expertise and knowledge of the models and her group have provided technical assistance.
Impact Successful application for an Asthma UK Innovations award. Studies also formed part of an unsuccessful application to the Wellcome Trust seeding drug discovery scheme and will form part of an application to the MRC DPFS scheme. These studies are the subject of a manuscript currently being finalized.
Start Year 2013
 
Title Lymph node replacement construct 
Description Lymphoedema is generally considered to be incurable, and in the UK occurs most often in post-surgical breast cancer patients. The standard of care to prevent metastases is to remove lymph nodes, which unfortunately also removes the principal lymph drainage pathway for the arm. It is estimated that up to ½ of 42,000 patients who receive these procedures in the UK will develop lymphoedema. Our patented implantable device aims to replace the fluid delivery role of native lymph nodes by imitating their fluid flow characteristics. Long-term goals include a series of additional design features that facilitate restoration and enhancement of immune function to enhance diagnosis and treatment of various cancers. 
IP Reference WO2016083784 
Protection Patent application published
Year Protection Granted 2014
Licensed No
Impact N/A
 
Title Bentley - ICiC2 - gripAble 
Description We are testing it for efficacy in small numbers of patients 
Type Therapeutic Intervention - Medical Devices
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2016
Development Status Actively seeking support
Impact Won NHS Innovation Prize and UK Stroke Forum Patients Carers and Public Involvement Prize 
 
Title Gunn - ICiC2 - Prototype Kinect v2 near mode sensor 
Description The system consists of a modified Microsoft Kinect v2 which is rigidly mounted inside the scanner bore of a PET/CT scanner. Software tracks the position of the subject's head using the 3D data provided by the Kinect v2. Currently we are acquiring 40 research PET/CT clinical brain scans with motion data to perform motion correction in the aim of reducing image blur. This is funded using a Medical Research Council Development Pathway Funding Scheme. 
Type Support Tool - For Fundamental Research
Current Stage Of Development Refinement. Clinical
Year Development Stage Completed 2015
Development Status Under active development/distribution
Impact The software and techniques developed could be applied to other aspects of healthcare such as respiratory monitoring. 
 
Description Bentley - ICiC 2 + 3 - ESC 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Presentation at conference
Year(s) Of Engagement Activity 2015
URL http://eurostroke.eu/esc-vienna-2015
 
Description Dickinson - ICiC 2 - BRAIN 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Brain & BrainPET, organised by the ISCBFM, address many of the controversial issues within the area of neuroscience research. 2015 will feature a state-of-the art scientific program and showcase novel discoveries and techniques with the goal of enhancing delegates' understanding of brain function under physiological and pathological conditions. Brain & BrainPET will feature acclaimed international experts, who will debate, discuss and analyse the most promising investigations in brain protection and neurodegeneration.
Year(s) Of Engagement Activity 2015
URL http://brain.kenes.com/Documents/Poster%20Supplement.pdf
 
Description Dickinson - ICiC2 - Gillespie Primary School, London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Robert Dickinson is doing outreach activities with Gillespie Primary School in Highbury, north London with their innovative Lab13 Science Lab. He visited Lab13 with one of his PhD students where they talked about the brain and the body with pupils from Years 2, 4 and 6.
Year(s) Of Engagement Activity 2016
 
Description Dickinson - ICiC2 - Imperial Festival 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Research group participated in Imperial Festival (15,000 attendees, May 2016, May 2014 & May 2013) with Research Zone display. We participated in an event for Imperial College Alumni & Donors (November 2014) - see http://bit.ly/1w6K6Gi and most recently (March 2015) at in an event as part of the Imperial Fringe series that focussed on how and why scientists and doctors use animals in research see http://bit.ly/1xrwoKh.
Year(s) Of Engagement Activity 2010,2013,2014,2015,2016
URL http://bit.ly/1w6K6Gi
 
Description Edwards, A - ICiC2 - C4 & ITV 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Dr Andrew Edwards gave interviews to both Channel 4 on this project for pieces timed to coincide with Jim O'Neil's report on the economic cost of AMR (14th May 2015). He is now on an expert list for both companies to provide interviews as needed in the future.
Year(s) Of Engagement Activity 2015
 
Description Edwards, A - ICiC2 - Twitter account 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Established a twitter account @bugsinblood - used this to highlight on-going work and related media interviews.
Year(s) Of Engagement Activity 2017
 
Description Elson - ICiC2 - Presentation at Hyperspectral Imaging & Applications Conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Poster presentation at conference Hyperspectral Imaging & Applications Conference, Ricoh Arena, Coventry
Year(s) Of Engagement Activity 2016
 
Description Elson - ICiC2 - The 4th International Conference on Biomedical Engineering and Biotechnology (ICBEB2015) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact The International Conference on Biomedical Engineering and Biotechnology (ICBEB) is an international meeting held once a year. This, the fourth International Conference on Biomedical Engineering and Biotechnology (ICBEB2015) will be held in Shanghai, China, during August 18th-21st, 2015, which has been organizing after ICBEB2014, ICBEB2013, and ICBEB2012 by the ICBEB Organizing Committee.
Year(s) Of Engagement Activity 2015
URL http://2015.icbeb.org/
 
Description Elson - ICiC2 - The Optoelectronics Global Conference 2015, Shenzhen, China 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Annual event co-located with China International Optoelectronic Exposition in Shenzhen China. The aim of this conference is to foster interactions among broad disciplines in the optoelectronics family.
Year(s) Of Engagement Activity 2015
 
Description Fuchter - ICiC2 - Imperial College Brain Sciences Division Away Day 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact A research talk by Dr Fuchter at the Imperial College Brain Sciences Division Away Day on his work (medicinal chemistry) to a non-specialist, but scientific audience.
Year(s) Of Engagement Activity 2015
 
Description Gunn - ICiC2 - PN Imperial Festival 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Imperial Festival showcases work performed at Imperial to the public, Friends of Imperial, and any other interested attendees. Over 12,000 people attended the festival in 2015. P. Noonan assisted B. Glocker at the Imperial Festival showcasing the head tracking and augmented reality software to over 10,000 attendees from the general public and Friends of Imperial over 3 days in May 2015.
Year(s) Of Engagement Activity 2015
URL https://www.imperial.ac.uk/be-inspired/festival/about/festival-2015/
 
Description Moore - ICiC2 - webcast seminar for the Lymphatic Education and Research Network 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact No public disclosures can be made until the intellectual property is protected. However, Prof. Moore made a general mention of new technologies being developed to treat oedema in a webcast seminar for the Lymphatic Education and Research Network, a charity aiming to raise awareness of this and other lymphatic disorders. Attendees from around the globe asked questions via a chat box afterward.
Year(s) Of Engagement Activity 2015
URL http://lymphaticnetwork.org/news-events/biomechanical-approach-lymphedema
 
Description Nowlan - ICiC2 - Imperial Festival Prototype Sensor 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact A prototype of our fetal movement monitor and data from its use were displayed at the Imperial College Festival in 2015. This is the principal public outreach event for Imperial College where research projects in the college are displayed to the general public. Our display involved a prototype of the device that members of the public could handle and assess, as well as see data on its use and ask questions related to its function. Over 1000 people saw the display and the prototype. The exhibition triggered several inquiries as to the medical importance of fetal movement, and allowed the public to actually handle and even wear the monitor. Very positive feedback was received with several queries relating to the medical impact and subsequent and commercial availability of the device.
Year(s) Of Engagement Activity 2015
URL https://www.imperial.ac.uk/be-inspired/festival/whats-on/
 
Description Posocco - ICiC2 - ELIMED Workshop, Italy 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Piero Posocco gave a presentation at the ELIMED workshop in Catania, Italy.

The ELIMED project aims to demonstrate the validity of new approaches based on laser- driven ion sources for potential future applications in medical and other multidisciplinary fields, including hadrontherapy. In 2018, a User-oriented beam-line, ELIMAIA (ELI Multidisciplinary Applications of laser-Ion Acceleration) equipped with diagnostics and dosimetry end-points will be commissioned at the ELI-Beamlines facility in the Czech Republic with the main goal to perform proof-of-principle experiments, dosimetry measurements and radiation biology investigations at high repetition rate. The main goal of the 3rd ELIMED workshop is to strengthen the collaboration among the international research groups involved in this challenging project and gather new ideas, proposals and additional requirements from a broad community of users coming from different fields (Physics, Biology, Medicine, Chemistry, Material Science, etc.) interested in exploiting the availability of non-conventional (laser-driven) ion beams at ELI-Beamlines.
Year(s) Of Engagement Activity 2016
URL https://agenda.infn.it/conferenceDisplay.py?confId=10978
 
Description Snelgrove - ICiC 2 - ATRDD 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Akari Therapeutics (NASDAQ: AKTX), an emerging growth, clinical-stage biopharmaceutical company, announced today that it will hold a Research and Development Day on April 24, 2017 in New York. The event will be hosted by members of Akari's executive leadership team and will feature presentations from investigators and independent scientific advisors. The meeting will cover three main areas:
* Interim results from the ongoing phase 2 trial in paroxysmal nocturnal hemoglobinuria (PNH)
will be presented by Dr Anita Hill, the lead investigator in the study. Dr Hill is a Consultant
Haematologist and Honorary Clinical Associate Professor at Leeds Teaching Hospital, which is
one of the world's largest treatment centers for PNH patients.
* Results from the pre-clinical development program targeting new disease opportunities for our
lead compound Coversin, focusing on its unique dual leukotriene B4 (LTB4)/C5 activity will be
presented by Dr Robert Snelgrove, National Heart and Lung Institute, Imperial College London
whose particular expertise lies in LTB4 and lung inflammation.
* New data on the pre-clinical pipeline, including the once-weekly subcutaneous formulation of
Coversin, will be presented by Professor Arne Skerra, Professor of Biological Chemistry at the
University of Munich and Chairman of XL-protein GmbH.
The presentation will be webcast simultaneously
Year(s) Of Engagement Activity 2017
URL http://www.akaritx.com/wp-content/uploads/2017/03/2017-03-17-RD-day-20173.pdf
 
Description Snelgrove - ICiC 2 - ATS 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Welcome to Washington, DC for the 2017 American Thoracic Society International Conference. The
conference, which is expected to draw more than 15,000 investigators, educators, and clinicians, is
truly the destination for pediatric and adult pulmonary, critical care, and sleep medicine professionals at
every level of their careers.
The conference is all about learning, networking and connections. Because it engages attendees
across many disciplines and continents, the ATS International Conference draws a large, diverse group
of participants, a dedicated and collegial community that inspires each of us to make a difference in
patients' lives, now and in the future. By virtue of its size - ATS 2017 features approximately 6,700
original research projects and case reports, 500 sessions, and 800 speakers - participants can attend
sessions and special events from early morning to the evening. At ATS 2017 there will be something for
everyone.
Year(s) Of Engagement Activity 2017
URL https://conference.thoracic.org/program/resources/2017/virtual-final-program.pdf
 
Description Snelgrove - ICiC 2 - ATS 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The roots of the American Thoracic Society reach back to 1905, when a small group of physicians decided that the best way to improve care for tuberculosis patients was to share their experiences and discoveries. Today, the ATS has grown into an international society with more than 16,000 members.
Year(s) Of Engagement Activity 2015
URL https://www.atsjournals.org/doi/book/10.1164/ajrccm-conference.2014
 
Description Snelgrove - ICiC 2 - BALR 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The British Association for Lung Research 2016 summer meeting entitled 'Fight the good fight: Host-pathogen interactions in the lung'. The meeting was held at the Edge conference venue at the University of Sheffield (27- 29th July).
Year(s) Of Engagement Activity 2016
URL http://medicine.dept.shef.ac.uk/news/index.php/2016/09/15/student-success-at-the-british-association...
 
Description Snelgrove - ICiC 2 - BCI 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Interviewed by BioCentury Innovations for an article detailing the potential clinical implications of my research and risks of conventional LTA4H inhibitors. BioCentury Innovations identifies commercially promising translational science and assesses the next steps required to develop the technology. In this manner they provide Innovations audience in R&D, business development, academia and the venture capital community with an early lead on fresh science with investment potential
Year(s) Of Engagement Activity 2015
URL https://www.biocentury.com/bc-innovations/targets-mechanisms/2015-12-03/lta4hs-pro-and-anti-inflamma...
 
Description Snelgrove - ICiC 2 - BSI 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The BSI's main objective is to promote and support excellence in research, scholarship and clinical practice in immunology for the benefit of human and animal health and welfare. The BSI seeks to help British immunology accomplish the highest possible goals. To meet this objective, the BSI undertakes the following:

Running innovative events in research, public engagement and education
Promoting and disseminating research and good practice in immunology, translational medicine and vaccination
Working with its members to develop the benefits of membership and the relevance of the Society
Providing bursaries and grants
Enhancing public awareness of immunology
Influencing policy and decision makers
Working with other societies
Year(s) Of Engagement Activity 2017
URL http://www.bsicongress.com/#
 
Description Snelgrove - ICiC 2 - BTS 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited speaker at British Thoracic Society 2017 meeting. The Science and Research Committee organised an outstanding line up of speakers for the Meeting, which was of interest to all health professionals involved in the care of patients with respiratory disease, as well as to biomedical scientists working on lung disease. The symposia programme contained some outstanding international speakers who, together with national experts, informed delegates of the very latest advances in the clinical, translational and basic science of lung disease.
Year(s) Of Engagement Activity 2017
URL https://www.brit-thoracic.org.uk/document-library/learning-hub/winter-meeting-2017/bts-winter-meetin...
 
Description Snelgrove - ICiC 2 - CU 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact CARL's Distilling Workshop Program in the USA is the original distilling workshop, now in its 20th year. The Distilling Workshop is a two-day comprehensive primer with distillation techniques demonstrated on commercial-scale copper pot distilleries - presented jointly by Chris Gerling, Enology Extension Associate of Cornell University's Brewing & Vinification Laboratory; Alexander Plank of CARL Distilleries and Nicolas Haase of B&D Technologies - CARL Distilleries' Americas office. The course agenda of the Workshop will alternate between theoretical presentations and discussions, and practical demonstrations on Cornell University's distilling system consisting of two state-of-the-art 50 liter capacity copper pot stills with finishing plate columns.
Year(s) Of Engagement Activity 2017
URL https://app.certain.com/profile/web/index.cfm?PKwebID=0x93725236e8&varPage=
 
Description Snelgrove - ICiC 2 - ECFC 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The ECFS annual conference provides a forum for all with a common interest in CF to meet and discuss their latest findings. This series of conferences began as the European Working Group for Cystic Fibrosis (EWGCF) with the first official meeting being held in Stockholm in 1970. True to the original tradition of the EWGCF, each year the conference is held in a different European location and is usually of 3 days duration.

The conference scientific programme is put together by an invited scientific committee and includes topics covering the entire spectrum of CF related issues. Invited experts from basic science, clinical and social care give presentations within plenary sessions, symposia, workshops, special interest groups, and meet the experts sessions. In addition an essential ingredient of the conference is the presentation of work following the submission of abstracts from all areas of interest in CF. These presentations illustrate the work being conducted in the multiple disciplines throughout the Scientific and Clinical CF Communities.
Year(s) Of Engagement Activity 2016
URL https://www.ecfs.eu/basel2016
 
Description Snelgrove - ICiC 2 - ELRIG 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited speaker at The European Laboratory Research & Innovation Group (ELRIG). This year's conference concentrated on topics that are breaking new ground in drug discovery research. The theme for this conference was "Cells as models of disease and new therapeutic agents". Under this umbrella they put together two tracks on Immunotherapy: oncology focused and non-oncology focused, as well as tracks on single-cell analysis and physiologically relevant cell models.
Year(s) Of Engagement Activity 2017
URL http://elrig.org/downloads/ri17/ri17_programme_web.pdf
 
Description Snelgrove - ICiC 2 - ERSLSC 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The ERS Lung Science Conference is at the forefront of basic and translational respiratory science and it is an essential event for budding respiratory researchers looking to boost their career. It offers a unique opportunity to network with peers from across the globe and will present cutting-edge abstracts on novel experimental lung research. The following features are organised every year:
Year(s) Of Engagement Activity 2018
URL https://www.ersnet.org/assets/static/path/documents/programme/LSC2018_programme_08.03.2018.pdf
 
Description Snelgrove - ICiC 2 - LIG 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact The BSI's London Immunology Group has organised a one-day meeting around the theme of immunotherapy and discussion on targeting the innate and adaptive immune systems.
Year(s) Of Engagement Activity 2016
URL https://www.immunology.org/events/innate-versus-adaptive-new-targets-in-immunological-therapy
 
Description Snelgrove - ICiC 2 - RIC 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited presentation to new company at the Roche Innovation Centre
Year(s) Of Engagement Activity 2018
URL https://www.s-ge.com/en/article/news/20174-roche-kaiseraugst
 
Description Stevens - ICiC 2 - BIM 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presented at the Bio-Inspired Materials 2016 Meeting. Based on the successful events held in 2012 and 2014 in Potsdam the scope of this conference was to provide an interdisciplinary platform for the discussion of novel developments and trends in the field of bio-inspired materials research. Accordingly, the whole spectrum of biological materials was covered. Topics encompassed the formation mechanisms as well as the characterization of complex-shaped and hierarchically structured multifunctional materials present in living nature. Based on this, a further key topic will be the consideration of these architectures as archetypes for the generation of novel functional materials with an expanded property spectrum.
The conference will address bio-inspired materials based on organic and/or inorganic phases including their mechanical, optical, electronic and magnetic properties as well as actuated systems. Further discussions will be dedicated to materials, which display their function in contact with biological systems, e.g. tissues. Moreover, theoretical modelling of the formation, structure and properties of biological and bio-inspired materials will play
a main role.
The programme will comprise several invited plenary lectures as well as oral and poster presentations. The conference is supported by the priority programme 1420 (Biomimetic Materials Research: Functionality by Hierarchical Structuring of Materials) of the Deutsche Forschungsgemeinschaft (DFG).
Year(s) Of Engagement Activity 2016
URL https://bioinspired2016.inventum.de/fileadmin/Tagungen/2016/02-EuroBio-inspired/Grafiken/Programmhef...
 
Description Stevens - ICiC 2 - EK 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The 10th World Biomaterials Congress in Montreal is dedicated to pioneering biomaterials researchers across the past four decades who have enabled innovation in the field, delivering on emerging technologies for global medical solutions.
Year(s) Of Engagement Activity 2016
URL http://tech4pco.com/wbc2016/flipbook/WBC2016.pdf
 
Description Stevens - ICiC 2 - HG 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact HG delivered the following oral presentation: Quantum dot-based detection of a tuberculosis-specific transcript signature, Materials Research Society Spring Meeting, San Francisco (April 2015)
Year(s) Of Engagement Activity 2015
URL http://epub.knepperpress.com/publication/index.php?i=249474&m=0&l=&p=318&pre=&ver=html5
 
Description Stevens - ICiC 2 - ISN 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact On February 3rd - 5th, 2016, the California NanoSystems Institute (CNSI) at the University of California, Los Angeles (UCLA) will host the 2016 International Symposium on Nanobiotechnology entitled "Nanomedicine from discovery to clinical reality: therapeutics, delivery and imaging."

The Symposium on Nanobiotechnology provides a forum for rigorous discussion of cutting edge science in the design, synthesis and fundamental study of nanotechnology and application in the areas of biology and medicine. Nanobiotechnology research encompasses an extremely diverse group of scientists working in the fields of physical sciences, life sciences and medicine. Fundamental research leads to translation of these findings into clinically applicable interventions, and this process will also be a focus of the meeting.

The 10th annual Symposium on Nanobiotechnology will cover new materials for drug delivery and cellular interactions, sensors and diagnostics, and new imaging techniques, as well as biological interactions such as immunological responses and in vivo targeting abilities. World-renowned researchers are invited speakers and young scientists will be given the opportunity to contribute talks and posters. Where relevant, discussion will focus upon possible translational aspects and real world applications with an eye to the unsolved and unmet problems of the future that Nanobiotechnology researchers collectively can solve.
Year(s) Of Engagement Activity 2016
URL http://cnsi.ctrl.ucla.edu/nanobiotechnology/pages/speakers
 
Description Stevens - ICiC 2 - PH 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact This four-day workshop will engage international experts in a lively scientific debate around the measurement of concentration of nanoparticle in media, their chemistry and the nature of critical interfaces.
Year(s) Of Engagement Activity 2015
URL http://www.npl.co.uk/upload/pdf/20150420-24_np-workshop_agenda-v2.pdf
 
Description Stevens - ICiC 2 - WBC 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited talk at the the World Biomaterials Congress
Year(s) Of Engagement Activity 2016
URL http://tech4pco.com/wbc2016/flipbook/WBC2016.pdf
 
Description Stevens - ICiC1 - HG 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact HG delivered the following oral presentation: Quantum dot-based detection of a tuberculosis-specific transcript signature, Materials Research Society Spring Meeting, San Francisco (April 2015)
Year(s) Of Engagement Activity 2015
URL http://epub.knepperpress.com/publication/index.php?i=249474&m=0&l=&p=318&pre=&ver=html5
 
Description Turner - ICiC2 - ACSG 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact 15 parents of food allergic children
Year(s) Of Engagement Activity 2012,2013,2014,2015
URL http://www.anaphylaxis.org.uk/events/support-group-map/