Interventional Biophotonics – A UK Healthcare Technology Accelerator Facility

Lead Research Organisation: University of Edinburgh

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding. It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.

Publications

10 25 50
 
Description Increase in University of Edinbrugh funded infrastructure aimed at supporting medical technology development
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Participation in a advisory committee
 
Description Uniting Clinical 'Pull' with Engineering and Physical Sciences 'Push'
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Challenge Led Applied Systems
Amount £463,914 (GBP)
Funding ID ST/S000763/1 
Organisation Science and Technologies Facilities Council (STFC) 
Sector Academic/University
Country United Kingdom
Start 10/2018 
End 09/2021
 
Description IRC Next Steps Plus: Photonic Pathogen Theranostics - Point-of-care image guided photonic therapy of bacterial and fungal infection
Amount £1,115,129 (GBP)
Funding ID EP/R018669/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start 03/2019 
End 03/2022
 
Title Generation of new medical devices 
Description Projects supported as part of the HTAF CiC are all collaborations between an NHS Lothian clinician and an engineer or physical scientist from one of five universities: University of Edinburgh, Heriot-Watt University, University of Strathclyde, University of Bath and University of Durham. Here, the clinician will identify an area of unmet clinical need - a clinical problem that currently lacks a satisfactory solution. HTAF will then match the clinician with an engineer/physical scientist who has a potential technological solution to that problem. For this specific round of CiC funding all potential solutions will be biophotonics-based. The projects funded by HTAF encompass a wide variety of subject areas, including (but not limited to) ophthalmology, neurodegeneration, inflammation, septic shock, post-surgical infection, liver injury and cancer. The devices that may result from these research projects may have great utility in a great number of areas of both treatment and research. 
Type Of Material Technology assay or reagent 
Year Produced 2019 
Provided To Others? No  
Impact N/A 
 
Title Generation of new medical devices 
Description Projects supported as part of the HTAF CiC are all collaborations between an NHS Lothian clinician and an engineer or physical scientist from one of five universities: University of Edinburgh, Heriot-Watt University, University of Strathclyde, University of Bath and University of Durham. Here, the clinician will identify an area of unmet clinical need - a clinical problem that currently lacks a satisfactory solution. HTAF will then match the clinician with an engineer/physical scientist who has a potential technological solution to that problem. For this specific round of CiC funding all potential solutions will be biophotonics-based. The projects funded by HTAF encompass a wide variety of subject areas, including (but not limited to) ophthalmology, neurodegeneration, inflammation, septic shock, post-surgical infection, liver injury and cancer. The devices that may result from these research projects may have great utility in a great number of areas of both treatment and research. 
Type Diagnostic Tool - Imaging
Current Stage Of Development Refinement. Non-clinical
Year Development Stage Completed 2019
Development Status Under active development/distribution
Impact N/A 
 
Description Article in Impact journal 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact An article outlining the purpose of the Healthcare Technology Accelerator Facility (HTAF), and informing interested parties about its raison d'être and the facilities and services which it can offer to help academics and companies translate medical technology. This article is now in press and is due to be published Q2 2019.
Year(s) Of Engagement Activity 2019
 
Description Engagement with Technology Transfer Offices of Consortium Universities 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Visit of HTAF Project Manager to the technology transfer offices (TTOs) of the institutions involved in this award. Provided the TTOs with an overview of HTAF and formulated a plan for how best to coordinate efforts in order to drive forward the translation of promising medical technologies being developed in those institutions.
Year(s) Of Engagement Activity 2018,2019
 
Description HTAF website launch 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Launch of the website for the Healthcare Technology Accelerator Facility. This provided an avenue by which interested parties could learn more about HTAF, the services/advice that HTAF can offer, and how they can access these things. HTAF has received numerous enquiries about potential use of HTAF facilities, with the resulting projects under development.
Year(s) Of Engagement Activity 2019
URL https://www.ed.ac.uk/healthcare-technology-accelerator
 
Description HTAF/Optima student collaboration 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact PHD Students on the Optima doctor training programme receive, over the course of their PHD, an education on matters related to business and commercialisation of science. For this cohort the students worked with the CiC-funded project teams in order to gain first-hand experience of the process of developing and attempting to translate a real-life piece of medical technology.
Year(s) Of Engagement Activity 2018,2019
URL https://www.optima-cdt.ac.uk/
 
Description Meeting with Director of N8 Research Partnership 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Conversation with Dr Annette Bramley, N8 Director. The purpose of this conversation was to introduce Dr Bramley to the concept of the Healthcare Technology Accelerator Facility and discuss opportunities for expansion into those other institutions that fall under the N8 umbrella.
Year(s) Of Engagement Activity 2019
URL https://www.n8research.org.uk/
 
Description NHS Health and Social Care Innovation Network 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Presentation outlining the purpose of HTAF and its collaboration with Codebase. We also led a panel looking at various healthcare challenges facing the NHS.
Year(s) Of Engagement Activity 2019
URL https://www.eventbrite.co.uk/e/meeting-of-the-nhs-health-and-social-care-innovation-network-tickets-...
 
Description Presentation at Health Innovation and Technologies Research Festival 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation of a poster at the Health Innovation and Technologies Research Festival (Heriot Watt University). The purpose was to inform the wider community about the Healthcare Technology Accelerator Facility and the facilities and services that can be accessed by researchers and companies.
Year(s) Of Engagement Activity 2019
URL https://www.hw.ac.uk/about/events/health-innovation-and-technologies-research.htm
 
Description Scottish Parliament Presentation 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Talk by Kev Dhaliwal to the Scottish purpose, outlining the concept behind HTAF and what HTAF can provide in order to increase the translation of promising healthcare technologies.
Year(s) Of Engagement Activity 2018