University of Southampton – Confidence in Concept 2017

Lead Research Organisation: University of Southampton


Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding. It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.


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Bostan LE (2021) Synthetic Nanoclay Gels Do Not Cause Skin Irritation in Healthy Human Volunteers. in ACS biomaterials science & engineering

Title - Development of Microfluidic Impedance Cytometry 
Description This is a microfluidic device designed to identify specific bacteria in tear fluid by flow cytometry, by measuring their forward and side-scatter profiles. 
Type Of Material Technology assay or reagent 
Year Produced 2018 
Provided To Others? No  
Impact The device is currently undergoing testing 
Description A method of determining the tuberculosis status in a subject, the method comprising obtaining a sample provided by a subject and determining the presence or absence of a protein of Seq ID No: 1, or a variant thereof, in the sample, wherein the presence of a protein of Seq ID No: 1, or a variant thereof, is diagnostic of tuberculosis in the subject. 
IP Reference WO2019102204 
Protection Patent application published
Year Protection Granted 2019
Licensed No
Impact This is part of a collaboration with the Highfield Diagnostics a paper-based diagnostic spin-out from the University of Southampton. They will use the biomarker to develop a diagnostic assay. The project has been awarded substantive EPSRC funding; £432,637.
Description Clinicians meet scientists networking events 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact The first Southampton joint meeting between the University Hospital Southampton NHS Trust and The University of Southampton took place as an engagement event for the MRC CiC award. This enabled clinicians to meet with engineers to discuss opportunities for collaboration to address real world health problems. this has led to joint activities with the health technologies centre at University of Southampton.
Year(s) Of Engagement Activity 2018
Description Included in a keynote presentation by TG Leighton at 2nd Global-NAMRIP conference (Kampala, Uganda, 3-7 March 2019) : 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact A presentation to an international conference on anti-micronbial resistance
Year(s) Of Engagement Activity 2019