Human infection challenge vaccine (HIC-vac) network

Lead Research Organisation: Imperial College London

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The Industrial Challenge Strategy Fund supplement is designed to bring diverse and flexible pump-priming activities to the Network with additional industrial involvement. This award will provide a support linkage, increasing UK Vaccine R&D activity around ‘proof of concept’ studies and can be used to support academic-industry partnerships and enhance academic and industry researchers' understanding of each other's needs and capabilities. This may be through people exchanges, creation of tecnology demonstrators, showcase events, workshops and pump-priming of grant activities.

Organisations

 
Description Developing ethical frameworks for human challenge studies
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description Foundations for regulatory guidelines for challenge agent manufacture
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
 
Title Due diligence 
Description Due diligence processes initiated and implemented in accordance to GCRF's demands. 
Type Of Material Improvements to research infrastructure 
Year Produced 2018 
Provided To Others? Yes  
Impact Due diligence processes in place and tested by audit by UKRI for future network awards. 
 
Title Finance systems to support pump-priming and training awards 
Description Template contracts, financial statements, and training award letters developed and approved by JRO. 
Type Of Material Improvements to research infrastructure 
Year Produced 2018 
Provided To Others? Yes  
Impact Mechanisms established for awarding pump-priming awards from Imperial College's systems. 
 
Title System for robust investigator decision-making for pump-priming awards established at board level, linking with university research infrastructure 
Description The NMB and ISAB were responsible for completing the application review process, following a process defined by the HIC-Vac management office. The Network Manager and the Comms Lead performed initial eligibility checks on applications received, which covered: • whether lead applicants and co-applicants were HIC-Vac members (if not they were asked to become members, which boosted membership numbers in this period); • whether the £100,000 limit had been breached, • funding duration no more than 12 months; • at least two different institutions per application • assessment of conflict of interest for reviewers. The Network Manager and Comms Lead allocated 3 reviewers from the NMB and ISAB to each application, avoiding both personal and institutional conflict of interest and attempting an even burden of reviews per reviewer. These allocations were reviewed by the Network Director and Deputy Director. All reviewers were sent all applications received for context, though they only had to complete reviews for their nominated applications. Scoresheets were completed with marks out of 30 for: • Scientific merit (10 marks), • track record (5 marks), • facilitating cross-network collaborations (5 marks), • strategic impact for the network (5 marks) • route to further funding (5 marks). Outliers were assessed by Ops group but concluded that with only 3 reviewers per application, adjusting for generous or harsh marking made not material difference to final rankings. A maximum of 3 strategic points per application were awarded by the Director as follows: • LMIC (1 mark) • Lead = Early Career Researcher (1 mark) • Equality and Diversity (1 mark) Each application were ranked firstly by Mean Average Score and secondly by Mean Average plus Strategic score. NMB did not wish to re-rank or review the scores. They agreed to fund the top 9 as per Average+StrategicRank. NMB and funders were happy that the review procedure used was robust. The Director summarised reviewer comments from scoresheets which was included as constructive feedback for applicants on notification emails. 
Type Of Material Improvements to research infrastructure 
Year Produced 2018 
Provided To Others? Yes  
Impact Guidelines are periodically published on the HIC-Vac website and templates available by request to the Network Manager for any other research groups wishing to set up a similar awarding process 
URL https://www.hic-vac.org/funding/pump-priming-funding
 
Description Academic partnerships through funding 
Organisation Central University of Rajasthan
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Centre for Infectious Disease Research in Zambia
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Christian Medical College, Vellore
Country India 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Kathmandu University
Country Nepal 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Kenyan Institute for Medical Research (KEMRI)
Country Kenya 
Sector Public 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Leiden University Medical Center
Country Netherlands 
Sector Multiple 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Liverpool School of Tropical Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Medical Research Council (MRC)
Department MRC Unit, The Gambia
Country Gambia 
Sector Public 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Medical Research Council (MRC)
Department Medical Research Council (MRC), MRC/UVRI Unit, Uganda
Country Uganda 
Sector Public 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation North Bristol NHS Trust
Country United Kingdom 
Sector Public 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation St George's University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Translational Health Science And Technology Institute
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Tribhuvan University of Nepal
Country Nepal 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Uganda Virus Research Institute
Country Uganda 
Sector Public 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation University of Kent
Country United Kingdom 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation University of Leicester
Country United Kingdom 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation University of Melbourne
Department Murdoch Children's Research Centre
Country Australia 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation University of Oxford
Department Oxford University Clinical Research Unit Vietnam (OUCRU)
Country Viet Nam 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Wellcome Trust
Department Mahidol University-Oxford Tropical Medicine Research Programme
Country Thailand 
Sector Academic/University 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Academic partnerships through funding 
Organisation Wellcome Trust
Department Malawi-Liverpool Wellcome Trust Clinical Research Programme
Country Malawi 
Sector Charity/Non Profit 
PI Contribution We have made financial contributions to these academic/publicly funded organisations via competitive applications for pump-priming or training funding awards, and a vaccine hesitancy project.
Collaborator Contribution Academic and publicly funded organisations have brought research expertise to the the partnership, to allow us to achieve our goal of supporting and boosting HIC studies globally.
Impact 9 pump-priming grants have been awarded and reported 6 month financial statements and progress against milestones. 5 pump-priming grants are in the final stages of signing contractual agreements. 4 early career researchers/students from LMICs were funded to attend the IVVN vaccinology course. 9 training grants have been awarded with 3 having reported outcomes.
Start Year 2017
 
Description Industry partnerships 
Organisation Antigen Discovery Inc
Country United States 
Sector Private 
PI Contribution Partnerships with Antigen Discovery Inc and SGS Life Sciences are a direct funding relationship - both are collaborators on pump-priming grants. The other industry partners have attended HIC-Vac meetings (Kick-off meeting, innovation sandpit and first annual general meeting) contributing expertise and exploring potential new collaborations.
Collaborator Contribution Industry expertise in collaboration with academic partners to achieve research outputs as defined in the pump-priming applications. Collaborators on further grants (ReSViTRAIN, GSK)
Impact 2 pump priming awards, 1 further award resulting from Network activities.
Start Year 2018
 
Description Industry partnerships 
Organisation GlaxoSmithKline (GSK)
Country Global 
Sector Private 
PI Contribution Partnerships with Antigen Discovery Inc and SGS Life Sciences are a direct funding relationship - both are collaborators on pump-priming grants. The other industry partners have attended HIC-Vac meetings (Kick-off meeting, innovation sandpit and first annual general meeting) contributing expertise and exploring potential new collaborations.
Collaborator Contribution Industry expertise in collaboration with academic partners to achieve research outputs as defined in the pump-priming applications. Collaborators on further grants (ReSViTRAIN, GSK)
Impact 2 pump priming awards, 1 further award resulting from Network activities.
Start Year 2018
 
Description Industry partnerships 
Organisation HUMABs Biomed, Bellinzona,Switzerland
Country Switzerland 
Sector Private 
PI Contribution Partnerships with Antigen Discovery Inc and SGS Life Sciences are a direct funding relationship - both are collaborators on pump-priming grants. The other industry partners have attended HIC-Vac meetings (Kick-off meeting, innovation sandpit and first annual general meeting) contributing expertise and exploring potential new collaborations.
Collaborator Contribution Industry expertise in collaboration with academic partners to achieve research outputs as defined in the pump-priming applications. Collaborators on further grants (ReSViTRAIN, GSK)
Impact 2 pump priming awards, 1 further award resulting from Network activities.
Start Year 2018
 
Description Industry partnerships 
Organisation Hvivo PLC
PI Contribution Partnerships with Antigen Discovery Inc and SGS Life Sciences are a direct funding relationship - both are collaborators on pump-priming grants. The other industry partners have attended HIC-Vac meetings (Kick-off meeting, innovation sandpit and first annual general meeting) contributing expertise and exploring potential new collaborations.
Collaborator Contribution Industry expertise in collaboration with academic partners to achieve research outputs as defined in the pump-priming applications. Collaborators on further grants (ReSViTRAIN, GSK)
Impact 2 pump priming awards, 1 further award resulting from Network activities.
Start Year 2018
 
Description Industry partnerships 
Organisation Janssen Pharmaceutica NV
Country Belgium 
Sector Private 
PI Contribution Partnerships with Antigen Discovery Inc and SGS Life Sciences are a direct funding relationship - both are collaborators on pump-priming grants. The other industry partners have attended HIC-Vac meetings (Kick-off meeting, innovation sandpit and first annual general meeting) contributing expertise and exploring potential new collaborations.
Collaborator Contribution Industry expertise in collaboration with academic partners to achieve research outputs as defined in the pump-priming applications. Collaborators on further grants (ReSViTRAIN, GSK)
Impact 2 pump priming awards, 1 further award resulting from Network activities.
Start Year 2018
 
Description Industry partnerships 
Organisation Sanofi
Department Sanofi Research Division
Country France 
Sector Private 
PI Contribution Partnerships with Antigen Discovery Inc and SGS Life Sciences are a direct funding relationship - both are collaborators on pump-priming grants. The other industry partners have attended HIC-Vac meetings (Kick-off meeting, innovation sandpit and first annual general meeting) contributing expertise and exploring potential new collaborations.
Collaborator Contribution Industry expertise in collaboration with academic partners to achieve research outputs as defined in the pump-priming applications. Collaborators on further grants (ReSViTRAIN, GSK)
Impact 2 pump priming awards, 1 further award resulting from Network activities.
Start Year 2018
 
Description LMIC partnerships 
Organisation Centre for Infectious Disease Research in Zambia
PI Contribution Provided funding via pump-priming or training awards.
Collaborator Contribution Capacity-building, early career training, and sharing expertise via pump-priming collaborations.
Impact 5 training awards 10 pump-priming awards either led by or involving an LMIC researcher.
Start Year 2018
 
Description LMIC partnerships 
Organisation Christian Medical College, Vellore
Country India 
Sector Academic/University 
PI Contribution Provided funding via pump-priming or training awards.
Collaborator Contribution Capacity-building, early career training, and sharing expertise via pump-priming collaborations.
Impact 5 training awards 10 pump-priming awards either led by or involving an LMIC researcher.
Start Year 2018
 
Description LMIC partnerships 
Organisation Kenyan Institute for Medical Research (KEMRI)
Country Kenya 
Sector Public 
PI Contribution Provided funding via pump-priming or training awards.
Collaborator Contribution Capacity-building, early career training, and sharing expertise via pump-priming collaborations.
Impact 5 training awards 10 pump-priming awards either led by or involving an LMIC researcher.
Start Year 2018
 
Description LMIC partnerships 
Organisation Mahidol University
Country Thailand 
Sector Academic/University 
PI Contribution Provided funding via pump-priming or training awards.
Collaborator Contribution Capacity-building, early career training, and sharing expertise via pump-priming collaborations.
Impact 5 training awards 10 pump-priming awards either led by or involving an LMIC researcher.
Start Year 2018
 
Description LMIC partnerships 
Organisation Medical Research Council (MRC)
Department MRC Unit, The Gambia
Country Gambia 
Sector Public 
PI Contribution Provided funding via pump-priming or training awards.
Collaborator Contribution Capacity-building, early career training, and sharing expertise via pump-priming collaborations.
Impact 5 training awards 10 pump-priming awards either led by or involving an LMIC researcher.
Start Year 2018
 
Description LMIC partnerships 
Organisation Translational Health Science And Technology Institute
PI Contribution Provided funding via pump-priming or training awards.
Collaborator Contribution Capacity-building, early career training, and sharing expertise via pump-priming collaborations.
Impact 5 training awards 10 pump-priming awards either led by or involving an LMIC researcher.
Start Year 2018
 
Description LMIC partnerships 
Organisation Uganda Virus Research Institute
Country Uganda 
Sector Public 
PI Contribution Provided funding via pump-priming or training awards.
Collaborator Contribution Capacity-building, early career training, and sharing expertise via pump-priming collaborations.
Impact 5 training awards 10 pump-priming awards either led by or involving an LMIC researcher.
Start Year 2018
 
Description LMIC partnerships 
Organisation University of Oxford
Department Oxford University Clinical Research Unit Vietnam (OUCRU)
Country Viet Nam 
Sector Academic/University 
PI Contribution Provided funding via pump-priming or training awards.
Collaborator Contribution Capacity-building, early career training, and sharing expertise via pump-priming collaborations.
Impact 5 training awards 10 pump-priming awards either led by or involving an LMIC researcher.
Start Year 2018
 
Description LMIC partnerships 
Organisation Wellcome Trust
Department Malawi-Liverpool Wellcome Trust Clinical Research Programme
Country Malawi 
Sector Charity/Non Profit 
PI Contribution Provided funding via pump-priming or training awards.
Collaborator Contribution Capacity-building, early career training, and sharing expertise via pump-priming collaborations.
Impact 5 training awards 10 pump-priming awards either led by or involving an LMIC researcher.
Start Year 2018
 
Description Feature in the FT 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact A feature in the FT discussing the ethics of human challenge studies. Article behind a paywall https://www.ft.com/content/1f8ad850-037b-11e9-99df-6183d3002ee1
Year(s) Of Engagement Activity 2018
 
Description HIC-Vac Independent Scientific Advisory Board (ISAB) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact - Established the HIC-Vac ISAB, with formal Terms of Reference.
- Membership is Fred Hayden (US, Chair), Camille LOCHT (France) and Richard Moxon (UK).
- ISAB members participated in scoring process for first pump-priming awards round and will meet by teleconference on 1st April, subsequently producing a short report for MRC on scientific and management progress of the HIC-Vac Network.
Year(s) Of Engagement Activity 2019
URL https://www.hic-vac.org/members/network-management-board/scientific-advisory-board
 
Description HIC-Vac Twitter channel 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Creation of a Twitter feed to share information including funding calls and publications with our Network. Now 410 followers.
Year(s) Of Engagement Activity 2017
URL https://twitter.com/hic_vac
 
Description HIC-Vac member conferences and events 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Three events have taken place to engage HIC-Vac members and encourage networking and collaborations: the Kickoff meeting (Nov 2017), the Innovation Sandpit (June 2018), the Annual General Meeting (Nov 2018).
Year(s) Of Engagement Activity 2017
 
Description HIC-Vac website creation and development 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Creation and development of an independent HIC-Vac website. Audience is primarily researchers, but also inclusive of a section for public information.
Year(s) Of Engagement Activity 2017
URL https://www.hic-vac.org/
 
Description Imperial Science Festival 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact HIC-Vac ran a stall at the Imperial Science Festival to discuss human infection studies with the public and run some engagement activities. Also an activity about vaccines for children.
Year(s) Of Engagement Activity 2018
 
Description MRC press release to announce HIC-Vac first funding round 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact The MRC (our primary funder) wrote a press release describing our activities and our first round of funding announcement. The story was covered by the Telegraph https://www.telegraph.co.uk/science/2018/07/02/volunteers-infected-deadly-strain-flu-make-vaccine-better/ and Daily Mail https://www.dailymail.co.uk/health/article-5913445/Would-flu-science-10-volunteers-given-deadly-H3N2-strain-summer.html.
Year(s) Of Engagement Activity 2018
URL https://mrc.ukri.org/news/browse/funding-boost-for-volunteer-infection-studies-to-help-combat-infect...
 
Description Participant videos 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Creation of short videos featuring volunteers who have taken part in human infection studies for the website and social media channels. The videos have also been shared by the institutes who ran the studies.
Year(s) Of Engagement Activity 2018
URL https://www.hic-vac.org/public-information/participants-stories
 
Description Telegraph feature 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Feature in the Telegraph naming HIC-Vac and quotes from Co-Director Prof Pollard and member Dr Andrea Collins.
Year(s) Of Engagement Activity 2019
URL https://www.telegraph.co.uk/news/0/students-paid-3500-catch-potentially-deadly-diseases-science/
 
Description The Global Health Network Platform 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Development of a platform to share resources, information and best practice linked to human challenge studies internationally, with a particular focus on supporting LMICs setting up new challenge studies. Site still being developed.
Year(s) Of Engagement Activity 2018
URL https://humaninfectionstudies.tghn.org/