Newcastle University – Confidence in Concept 2019
Lead Research Organisation:
Newcastle University
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
The Confidence in Concept (CIC) scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions to flexibly support a portfolio of early stage translational research projects. CIC is designed to accelerate the transition from discovery research to viable translational projects by supporting preliminary studies to establish proof-of-concept so that the approach will then become competitive for more substantial translational funding.
Publications
Elshehabi M
(2022)
Walking parameters of older adults from a lower back inertial measurement unit, a 6-year longitudinal observational study.
in Frontiers in aging neuroscience
Rehman RZU
(2022)
Investigating the Impact of Environment and Data Aggregation by Walking Bout Duration on Parkinson's Disease Classification Using Machine Learning.
in Frontiers in aging neuroscience
Scott K
(2022)
Design and validation of a multi-task, multi-context protocol for real-world gait simulation.
in Journal of neuroengineering and rehabilitation
Zia Ur Rehman R
(2021)
Predicting the Progression of Parkinson's Disease MDS-UPDRS-III Motor Severity Score from Gait Data using Deep Learning.
in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
| Description | GlycoScore: Superior prostate cancer diagnosis using a simple blood test |
| Amount | £150,000 (GBP) |
| Funding ID | NIHR202523 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2021 |
| End | 02/2022 |
| Description | Mobilise-D extension |
| Amount | £1,000,000 (GBP) |
| Organisation | Michael J Fox Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 11/2022 |
| Description | Targeting GALNT7 to develop new drugs for the personalised treatment of prostate cancer |
| Amount | £513,099 (GBP) |
| Organisation | Prostate Cancer UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2022 |
| Description | Transforming Parkinson's disease clinical management with integrated digital health technologies |
| Amount | £500,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2023 |
| End | 07/2024 |
| Description | Participation in meetings, testing material provided by MIP Discovery |
| Organisation | MIP Diagnostics |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | We have discussed licensing our technology with MIP Discovery and an upcoming paper. We also discussed the opportunity of evaluating new material by MIP Discovery, which will add impact to our platform since we can measure multiple markers. |
| Collaborator Contribution | As above |
| Impact | We are at the early discussion stages |
| Start Year | 2022 |
| Description | We are working with Biorad to develop antibodies for our ELISA test |
| Organisation | Bio-Rad Laboratories, Inc |
| Department | Bio-Rad Laboratories Ltd. |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | This collaboration was set up in August 2022 by the Project Team funding by CiC Project. Name of Project:- Care Pathway analysis and further validation for GlycoScore: a novel blood test for prostate cancer. Working to establish antibodies for our ELISA test |
| Collaborator Contribution | As above |
| Impact | No Outputs to report at present |
| Start Year | 2022 |
| Description | A meeting with prostate cancer patients in Manchester to discuss our research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Prostate Cancer Research meet the scientists day August 2022. Interaction with patients to discuss research on prostate cancer |
| Year(s) Of Engagement Activity | 2022 |
| Description | A panel discussion about the early diagnosis of prostate cancer with 150 audience members |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prostate Cancer UK The Panel meeting August 2022. Questions and Answer Session on topic. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Creation of dissemination video with CiC project overview |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Creation of dissemination video with CiC project overview (Collaboration with Master student - Oliver Latham). This video is promoting the CiC Project which looks at translating digital healthcare to enhance clinical management : evaluating the effect of medications on mobility in people with PD. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.youtube.com/watch?v=CpUpVp1myhg |
| Description | Poster presentation at ISPGR 2022 World Congress on CiC protocol (July 2022) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation given by Project Leads for Translating Digital Healthcare to enhance clinical management: evaluating the effect of medication on mobility in people with PD. Various questions were raised and the promotion of CiC Award given |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://ispgr.org/2022-congress/ |
| Description | Poster presentation at ISPGR 2022 World Congress on CiC review work |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presented by CiC Project Leads for: Translating Digital Healthcare to enhance clinical management: evaluating the effect of medication on mobility in people with PD |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://ispgr.org/2022-congress/ |
| Description | Presentation and discussion with Prostate Cancer UK North East Hub |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation and discussion with Prostate Cancer UK North East Hub around our research and ongoing work |
| Year(s) Of Engagement Activity | 2022 |
| Description | Presentation at BioMedEng Conference (8-9/09/2022) stemming from UG work and analysis on feasibility and usability data of the CiC project (poster) |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Poster presented by Project Leads of CiC Project - Translating Digital Healthcare to enhance clinical management: evaluating the effect of medication on mobility in people with PD. Good questions were raised at the event and promotion of CiC gained. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://biomedeng.org/biomedeng22/ |
| Description | Production of a video as an opportunity to gain insight into the development and optimisation of a sensor platform |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Production of a video that was showcased at a planned focus group which allowed us to have an opportunity to gain insight into the design of the proposed device |
| Year(s) Of Engagement Activity | 2023 |
| Description | Work with Biorad to develop antibodies for ELISA test |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | We are working with Biorad to develop antibodies for our ELISA test |
| Year(s) Of Engagement Activity | 2022 |
| Description | Working with Attomarker to carry out testing on their platform |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | We are working with Attomarker to use our test on their platform |
| Year(s) Of Engagement Activity | 2022 |
| Description | Working with M2M to develop CE/A marked diagnostic kit |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | Working with MedTech to Market (M2M) to develop our CE/A marked diagnostic kit |
| Year(s) Of Engagement Activity | 2022 |