MRC Lifecourse Epidemiology Centre - Core Support
Lead Research Organisation:
University of Southampton
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
MRC Lifecourse Epidemiology Centre: Technical Summary
Overview
The MRC will use lifecourse epidemiological methods to reduce the population burden of chronic musculoskeletal disease and disability. These approaches will optimize musculoskeletal health (bone, muscle and joint) through the development and testing of lifestyle, behavioural and pharmacological interventions informed by a series of observational studies; and by using these findings to influence health policy.
The specific aims of the MRC Lifecourse Epidemiology Centre will be to:
• Delineate the environmental influences, throughout the lifecourse, of age-related musculoskeletal diseases (osteoporosis, osteoarthritis and sarcopenia).
• Use findings to develop and test population based and targeted interventions to improve musculoskeletal health throughout the lifecourse.
• Maintain and develop the long-term cohorts/trials assembled in Southampton as national and international resources to explore the mechanisms underlying the developmental origins and later causes of musculoskeletal and metabolic health and disease.
• Minimise the adverse impact of musculoskeletal disorders on ability to work, by undertaking a programme running alongside the Versus Arthritis-MRC Centre for Musculoskeletal Health and Work.
• Provide data management and statistical support for a series of preconceptual and pregnancy-based cardiometabolic intervention studies maintained at the fore-running MRC Lifecourse Epidemiology Unit (HeLTI, TALENT, NiPPeR, EACH-B and WRAPPED).
• Inform health policy and promote training, research capacity development, knowledge transfer and public engagement in lifecourse epidemiology.
The aims of the MRC Lifecourse Epidemiology Centre will be delivered through three linked scientific programmes:
1. Musculoskeletal health in later life (PI: Professor Cyrus Cooper)
2. Determinants of musculoskeletal health in the mid-lifecourse (PI: Professor Karen Walker-Bone)
3. Early development and risk of adult musculoskeletal disease (PI: Professor Nicholas Harvey)
Overview
The MRC will use lifecourse epidemiological methods to reduce the population burden of chronic musculoskeletal disease and disability. These approaches will optimize musculoskeletal health (bone, muscle and joint) through the development and testing of lifestyle, behavioural and pharmacological interventions informed by a series of observational studies; and by using these findings to influence health policy.
The specific aims of the MRC Lifecourse Epidemiology Centre will be to:
• Delineate the environmental influences, throughout the lifecourse, of age-related musculoskeletal diseases (osteoporosis, osteoarthritis and sarcopenia).
• Use findings to develop and test population based and targeted interventions to improve musculoskeletal health throughout the lifecourse.
• Maintain and develop the long-term cohorts/trials assembled in Southampton as national and international resources to explore the mechanisms underlying the developmental origins and later causes of musculoskeletal and metabolic health and disease.
• Minimise the adverse impact of musculoskeletal disorders on ability to work, by undertaking a programme running alongside the Versus Arthritis-MRC Centre for Musculoskeletal Health and Work.
• Provide data management and statistical support for a series of preconceptual and pregnancy-based cardiometabolic intervention studies maintained at the fore-running MRC Lifecourse Epidemiology Unit (HeLTI, TALENT, NiPPeR, EACH-B and WRAPPED).
• Inform health policy and promote training, research capacity development, knowledge transfer and public engagement in lifecourse epidemiology.
The aims of the MRC Lifecourse Epidemiology Centre will be delivered through three linked scientific programmes:
1. Musculoskeletal health in later life (PI: Professor Cyrus Cooper)
2. Determinants of musculoskeletal health in the mid-lifecourse (PI: Professor Karen Walker-Bone)
3. Early development and risk of adult musculoskeletal disease (PI: Professor Nicholas Harvey)
Organisations
- University of Southampton (Lead Research Organisation)
- World Health Organization (WHO) (Collaboration)
- University of Manchester (Collaboration)
- UNIVERSITY OF NOTTINGHAM (Collaboration)
- National Institute of Health and Medical Research (INSERM) (Collaboration)
- University of Gothenburg (Collaboration)
- University College Dublin (Collaboration)
- Newcastle University (Collaboration)
- University of South Carolina (Collaboration)
- UNIVERSITY OF OXFORD (Collaboration)
- University of Sheffield (Collaboration)
- UNIVERSITY OF BIRMINGHAM (Collaboration)
- Erasmus University Rotterdam (Collaboration)
- UNIVERSITY OF LIVERPOOL (Collaboration)
- Edith Cowan University (Collaboration)
- University of Bristol (Collaboration)
Publications
Acton RJ
(2021)
The genomic loci of specific human tRNA genes exhibit ageing-related DNA hypermethylation.
in Nature communications
Adams J
(2021)
2019 EULAR points to consider for non-physician health professionals to prevent and manage fragility fractures in adults 50 years or older.
in Annals of the rheumatic diseases
Antoun E
(2022)
Epigenome-wide association study of sarcopenia: findings from the Hertfordshire Sarcopenia Study (HSS).
in Journal of cachexia, sarcopenia and muscle
Antoun E
(2021)
Altered H19/miR-675 expression in skeletal muscle is associated with low muscle mass in community-dwelling older adults
in JCSM Rapid Communications
Ardissino M
(2022)
Pericardial adiposity is independently linked to adverse cardiovascular phenotypes: a CMR study of 42 598 UK Biobank participants.
in European heart journal. Cardiovascular Imaging
Aubert AM
(2022)
Predictors of maternal dietary quality and dietary inflammation during pregnancy: An individual participant data meta-analysis of seven European cohorts from the ALPHABET consortium.
in Clinical nutrition (Edinburgh, Scotland)
Barnsley J
(2021)
Pathophysiology and treatment of osteoporosis: challenges for clinical practice in older people.
in Aging clinical and experimental research
| Description | Co-authorship of European guidance on osteoporosis in men (ESCEO) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Co-authorship of European position on Real World Evidence in osteoporosis |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Co-authorship of Royal Osteoporosis Society APPG enquiry into FLS (NCH) 2021 |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Co-authorship of Royal Osteoporosis Society APPG enquiry into Primary fracture prevention(NCH) 2022 |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | European guidance on very high fracture risk (NCH, CC) |
| Geographic Reach | Europe |
| Policy Influence Type | Membership of a guideline committee |
| Description | National Osteoporosis Guideline Group Advisory Committee (NCH, CC) |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Developmental origins of child neurodevelopment: Novel approaches to clinical risk prediction using an international metadataset. |
| Amount | £364,324 (GBP) |
| Funding ID | MR/V029169/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2021 |
| End | 10/2027 |
| Description | Does maternal gestational vitamin D supplementation influence offspring DNA methylation in childhood? |
| Amount | £29,984 (GBP) |
| Funding ID | SGL023\1072 |
| Organisation | Academy of Medical Sciences (AMS) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2020 |
| End | 12/2021 |
| Description | Does pregnancy vitamin D supplementation alter trajectories of body composition and bone mineralisation from early childhood to adolescence? Follow-up of a randomised placebo-controlled trial. |
| Amount | £187,294 (GBP) |
| Funding ID | GN2969 |
| Organisation | Action Medical Research |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2023 |
| End | 03/2026 |
| Description | MRC National Musculoskeletal Network |
| Amount | £150,847 (GBP) |
| Funding ID | MC_PC_21022 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2022 |
| End | 02/2024 |
| Description | NIHR Clinical Lectureship |
| Amount | £250,000 (GBP) |
| Funding ID | CL-2020-26-002 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2021 |
| End | 11/2026 |
| Description | Nutritional determinants of skeletal development and bone loss: an investigation using a novel computer vision assessment of bone microarchitecture |
| Amount | £36,000 (GBP) |
| Organisation | University of Southampton |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 08/2022 |
| End | 09/2025 |
| Description | Preventing broken bones in older people: from research to policy to practice |
| Amount | £29,566 (GBP) |
| Funding ID | MRF-145-0011-DG-HARV-C0913 |
| Organisation | Medical Research Council (MRC) |
| Department | Medical Research Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 09/2022 |
| Description | UKRI WCL Capital funding 2020 2021 DXA and MSK Scanning Suite |
| Amount | £216,857 (GBP) |
| Funding ID | 4050801857 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2020 |
| End | 03/2021 |
| Title | Novel seasonal adjustment for vitamin D concentrations |
| Description | Novel method for adjusting the vitamin D concentrations for season, independent of assays used. |
| Type Of Material | Model of mechanisms or symptoms - human |
| Provided To Others? | No |
| Impact | Tracking of 25-hydroxyvitamin D status during pregnancy: the importance of vitamin D supplementation. Moon RJ, Crozier SR, Dennison EM, Davies JH, Robinson SM, Inskip HM, Godfrey KM, Cooper C, Harvey NC. Am J Clin Nutr. 2015 Nov;102(5):1081-7. doi: 10.3945/ajcn.115.115295. |
| Title | Dataset for paper :Maternal and fetal genetic variation in vitamin D metabolism and umbilical cord blood 25-hydroxyvitamin D - Supplemental Tables and Figures |
| Description | Supplemental tables and figures to accompany the paper "Maternal and fetal genetic variation in vitamin D metabolism and umbilical cord blood 25-hydroxyvitamin D" by RJ Moon, LDF Cooke, S D'Angelo, EM Curtis, P Titcombe, JH Davies, KM Godfrey, JK Cleal, RM Lewis, C Cooper & NC Harvey |
| Type Of Material | Database/Collection of data |
| Year Produced | 2022 |
| Provided To Others? | Yes |
| Impact | Supplemental tables and figures to accompany the paper "Maternal and fetal genetic variation in vitamin D metabolism and umbilical cord blood 25-hydroxyvitamin D" by RJ Moon, LDF Cooke, S D'Angelo, EM Curtis, P Titcombe, JH Davies, KM Godfrey, JK Cleal, RM Lewis, C Cooper & NC Harvey |
| URL | https://eprints.soton.ac.uk/455706/ |
| Title | SPRING Trial |
| Description | SPRING Trial |
| Type Of Material | Database/Collection of data |
| Year Produced | 2021 |
| Provided To Others? | No |
| Impact | SPRING Trial |
| Description | ALPHABET |
| Organisation | Erasmus University Rotterdam |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | National Institute of Health and Medical Research (INSERM) |
| Department | Center for Epidemiological and Bio Statistics Research at Sorbonne |
| Country | France |
| Sector | Public |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | University College Dublin |
| Department | School of Physics |
| Country | Ireland |
| Sector | Academic/University |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | University College Dublin |
| Country | Ireland |
| Sector | Academic/University |
| PI Contribution | WP5, bone outcomes |
| Collaborator Contribution | Consortium |
| Impact | Ongoing |
| Start Year | 2017 |
| Description | ALPHABET |
| Organisation | University of Bristol |
| Department | Biomedical Research Unit in Nutrition, Diet and Lifestyle |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | WP5, bone outcomes |
| Collaborator Contribution | Consortium |
| Impact | Ongoing |
| Start Year | 2017 |
| Description | ALPHABET |
| Organisation | University of South Carolina |
| Department | Arnold School of Public Health |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALSPAC placenta |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Placental determinants of bone mass |
| Collaborator Contribution | Placental determinants of bone mass |
| Impact | Ongoing |
| Start Year | 2013 |
| Description | AUGMENT UK Biobank collaboration |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | AUGMENT UK Biobank collaboration |
| Collaborator Contribution | AUGMENT UK Biobank collaboration |
| Impact | AUGMENT UK Biobank collaboration |
| Start Year | 2017 |
| Description | AUGMENT UK Biobank collaboration |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | AUGMENT UK Biobank collaboration |
| Collaborator Contribution | AUGMENT UK Biobank collaboration |
| Impact | AUGMENT UK Biobank collaboration |
| Start Year | 2017 |
| Description | Abdominal Aortic Calcification Collaboration |
| Organisation | Edith Cowan University |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Collaboration using AI techniques to detect abdominal aortic calcification. Collaboration between Edith Cowan University and University of Western Australia; McMaster University; University of Manitoba; University of Southampton. Southampton providing UK biobank expertise. |
| Collaborator Contribution | Collaboration using AI techniques to detect abdominal aortic calcification. Collaboration between Edith Cowan University and University of Western Australia; McMaster University; University of Manitoba; University of Southampton. Southampton providing UK biobank expertise. |
| Impact | Ongoing |
| Start Year | 2021 |
| Description | MAVIDOS Childhood Follow up |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Recruitment to MAVIDOS 6 year follow-up in Sheffield |
| Collaborator Contribution | Recruitment to MAVIDOS six-year follow-up in Sheffield |
| Impact | N/A |
| Start Year | 2016 |
| Description | MAVIDOS Childhood Follow-up Oxford |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Recruitment of children to MAVIDOS six-year follow-up in Oxford |
| Collaborator Contribution | Recruitment of children to MAVIDOS six-year follow-up in Oxford |
| Impact | N/A |
| Start Year | 2016 |
| Description | MAVIDOS Oxford CVD |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Vitamin D in pregnancy and offspring cardiac structure and function |
| Collaborator Contribution | Vitamin D in pregnancy and offspring cardiac structure and function |
| Impact | Ongoing |
| Start Year | 2015 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | Newcastle University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Birmingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Liverpool |
| Department | School of Medicine Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Nottingham |
| Department | School of Biology Nottingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Sheffield |
| Department | Sheffield Biorepository |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | SARCOFRAX |
| Organisation | University of Gothenburg |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | Developing sarcopenia outcome risk calculator |
| Collaborator Contribution | Developing sarcopenia outcome risk calculator |
| Impact | ongoing |
| Start Year | 2020 |
| Description | SARCOFRAX |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Developing sarcopenia outcome risk calculator |
| Collaborator Contribution | Developing sarcopenia outcome risk calculator |
| Impact | ongoing |
| Start Year | 2020 |
| Description | WHO Clinical Consortium on Health Ageing |
| Organisation | World Health Organization (WHO) |
| Country | Global |
| Sector | Public |
| PI Contribution | Contribution to World Report on Ageing and Health, and project to operationalise concept of intrinsic capacity |
| Collaborator Contribution | Organisation of WHO workshop on intrinsic capacity |
| Impact | WHO Global Report on Ageing and Health |
| Start Year | 2016 |
| Title | PHENOTYPE PREDICTION BY DETERMINING THE METHYLATION STATUS OF GENES |
| Description | Phenotypic characteristics selected from obesity and/or adiposity, bone health, and cardiovascular disease, may be predicted by determining the methylation status of one or more CpG dinucleotides of the, SLC6A4, CDKN2A, FEN1 and BACH1 genes. |
| IP Reference | WO2015067952 |
| Protection | Patent application published |
| Year Protection Granted | 2015 |
| Licensed | No |
| Impact | EpiGen Consortium |
| Title | PREDICTIVE USE OF CPG METHYLATION |
| Description | RXRA for obesity or adiposity, body mass index and limb fat as an indicator of body fat distribution |
| IP Reference | EP2391730 |
| Protection | Patent application published |
| Year Protection Granted | 2011 |
| Licensed | No |
| Impact | EpiGen Consortium |
| Title | MAVIDOS trial vitamin D intervention |
| Description | Vitamin D supplementation |
| Type | Preventative Intervention - Nutrition and Chemoprevention |
| Current Stage Of Development | Wide-scale adoption |
| Year Development Stage Completed | 2021 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | Maternal vitamin D supplementation led to greater bone mass in the offspring for winter births |
| Title | SPRING Pregnancy vitamin D supplementation trial |
| Description | Trial of vitamin D supplementation during pregnancy |
| Type | Preventative Intervention - Nutrition and Chemoprevention |
| Current Stage Of Development | Wide-scale adoption |
| Year Development Stage Completed | 2021 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | Trial of vitamin D supplementation during pregnancy |
| Description | A talk at CIMA/CMAR Joint Meeting, Birmingham |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | CIMA/CMAR Network Meeting/Presentation |
| Year(s) Of Engagement Activity | 2023 |
| Description | ACCIA 2022 Committee Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | This meeting was held via Zoom on 9th June 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | ASBMR online (EC) 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at ASBMR, USA |
| Year(s) Of Engagement Activity | 2021 |
| Description | ASBMR-ECTS debate EC 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | ASBMR-ECTS debate EC 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Academy Advisory Committee Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 21st April 2021. The meeting was attended by over 10 people. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.theros.org.uk |
| Description | Article for University of Southampton Medically Speaking Blog |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Article witten for Medically Speaking Blog, University of Southampton |
| Year(s) Of Engagement Activity | 2023 |
| Description | BRS ECTS Liverpool |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speech at BRS ECTS Liverpool |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://boneresearchsociety.org/meetings/198/ |
| Description | BSR Conference Speech |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speech and participant at BSR Conference, Manchester |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.rheumatology.org.uk/bsr24 |
| Description | BSRA MRC National Musculoskeletal Ageing Network joint symposium 2023 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | BSRA MRC National Musculoskeletal Ageing Network joint symposium 2023 |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://bsra.org.uk/events/bsra-asm-2023/ |
| Description | Blog and E News |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Professor Nicholas Harvey has been appointed as Director of the MRC LEC. He takes over from Cyrus Cooper on 1st April 2023 |
| Year(s) Of Engagement Activity | 2023 |
| Description | Centre of Excellence Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 7th June 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Chair ASBMR IOF joint session at ASBMR 2021 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chair ASBMR IOF joint session at ASBMR 2021 (NCH) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Cyrus Cooper in top 0.1% of researches |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Clarivate reported that Cyrus Cooper was one of 13 top researches based on citations - Nick Harvey, Catherine Gale were also included. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.osteoporosis.foundation/news/iof-president-cyrus-cooper-recognized-2023-best-scientist-a... |
| Description | DOHAD Conference 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended the DOHAD International Conference. This was held between 27th-31st August 2022. Over 1,000 people attended. |
| Year(s) Of Engagement Activity | 2022 |
| Description | DOHAD Society webinar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | DOHAD Society webinar |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://dohadsoc.org/webinars/ |
| Description | E News article |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Cyrus wrote an article for E News entitled '40 years of pioneering reseach' |
| Year(s) Of Engagement Activity | 2023 |
| Description | ECTS 2021 Congress |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper gave a presentation entitled: 'Building Bones in Young Individuals' at the ECTS 2021 Congress. This was attended by over 100 people. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.ects2021.org |
| Description | ESCEO Working Group |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended the ESCEO Working Group on September 9th 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Editorial Team invite |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Kate Ward and Nick Harvey joined the editorial team of the journals of osteoporosis international and archives of osteoporosis |
| Year(s) Of Engagement Activity | 2023 |
| Description | European Geriatric Medical Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | speech/presentation for EUGMS |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://eugms2023.com/ |
| Description | Expert Health Article in The Telegraph |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Kate Ward gave an interview for the Expert Health feature in the Telegraph newspaper. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.telegraph.co.uk/health-fitness/conditions/bones-joints/im-a-bone-health-expert-and-this-... |
| Description | External Meeting at The Usher Institute, Edinburgh |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended the NINE Edinburgh BioQuater meeting on 24th May 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | FRAX Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attending a FRAX meeting, held by University of Sheffield on 4th March 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Fellowship Committee Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended this meeting on 10th May 2021. There were over 100 people in attendance. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.acmedsci.ac.uk |
| Description | IOF symposium at DVO Congress, Salzburg |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | IOF at DVO conference |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.emedevents.com/c/medical-conferences-2023/annual-congress-dvo-osteology-2023 |
| Description | Invited Chair joint IOF SIBOMM session (NCH) 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited Chair joint IOF SIBOMM session (NCH) 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Invited presentation BRADOO 2021 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited presentation BRADOO 2021 (NCH) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Invited presentation at Belgian Bone Club 2022 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited presentation at Belgian Bone Club 2022 (NCH) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited presentation at SICOT (NCH) 21 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited presentation at SICOT (NCH) 21 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Launch of the MRC Lifecourse Epidemiology Centre & MRC National Musculoskeletal Group |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | The launch of the MRC Lifecourse Epidemiology Centre and the MRC National Musculoskeletal Ageing Network was an online event. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://us06web.zoom.us/rec/play |
| Description | MRC National Musculoskeletal Ageing Network ECR/MCR developmental sessions |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | MRC National Musculoskeletal Ageing Network ECR/MCR developmental sessions |
| Year(s) Of Engagement Activity | 2022 |
| Description | MRC National Musculoskeletal Ageing Network Seminars |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | MRC National Musculoskeletal Ageing Network Seminars |
| Year(s) Of Engagement Activity | 2022 |
| Description | MTP WCO (EC) 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Meet The Expert session at World Congress and Osteoporosis |
| Year(s) Of Engagement Activity | 2021 |
| Description | MTP WCO 2021 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Meet The Professor session at World Congress in Osteoporosis 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | MyAge London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | MyAge published a roadmap to help shape the future of muscle resilience research |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ukanet.org.uk/myage/news-events/ |
| Description | MyAge official launch |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Enews reported that MyAge was officially launched at a special event at the Wellcome Collection in London. Professor Keith Godfrey and Professor Nick Harvey attended |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ukanet.org.uk/myage/our-purpose/ |
| Description | Participant in Committee Meeting HDR UK QQR Research Driver Programmes Sub-committee meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper was part of this meeting which took place on 25 May 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Presentation at BSR (EC) 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at British Society for Rheumatology |
| Year(s) Of Engagement Activity | 2021 |
| Description | Presentation at Prizegiving event |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper presented a prize at the Rank Prize 50th Anniversary event. This took place on 4th July 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Presentation at WCO 2021 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at World Congress in Osteoporosis 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Presentation given at ESCEO Meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus gave a presentation entitled "Optamising the prescription of oral Bisphosphonates" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Presentation to local GP Surgey |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presention/talk on osteoporosis to St Francis Surgery, Hedge End |
| Year(s) Of Engagement Activity | 2023 |
| Description | Presentations at WCO (EC) 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at World Congress in osteoporosis |
| Year(s) Of Engagement Activity | 2021 |
| Description | Public engagement session on osteoporosis with primary care patients |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Speech on Osteoporosis to St Thomas's Practice |
| Year(s) Of Engagement Activity | 2019,2023 |
| Description | REF 2021 University Results Presentation |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended the REF2021 University Results Presentation meeting on 9th May 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Royal Osteoporosis Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | speech and presentation |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://theros.org.uk/healthcare-professionals/courses-and-cpd/osteoporosis-conference/ |
| Description | Royal Osteoporosis Society public event 2021 (NCH) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Working group vitamin D ESCEO 21 (NCH) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Saudi NH first advisory Committee Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended this meeting on 18th May 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Southampton Women's Survey Celebration Event |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | As part of the 50th Anniversary of the NIHR BRC, the Southampton Women's Survey were chosen to represent some of the research that has taken place in Southampton. The BRC funded an evening at the City Art Gallery in Southampton for 50 SWS participants and their family or friends. The speakers who talked about the study findings were Prof. Cyrus Copper, Prof Keith Godfrey, Prof Janis Baird and Prof Hazel Inskip who wrote and sang a song at the end of the presentation whilst playing her ukulele. SWS staff in attendance and who organised the logistics for the event were research nurses, Julia Hammond, Nicole Minette, Karen McGill and Tina Horsfall. They received requests about further participation or involvement, the audience reported change in views, opinions or behaviours, requests for further information. Children were also recruited for PPI for the BRC. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Speaker at ArLAR Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper was a speaker at the ArLAR Conference. He gave a talk entitled 'Nutritional Approach of Osteoporosis and Fracture Prevention'. This took place on 5th March 2021 |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.arabrheumatology.org |
| Description | Speech |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper gave a speech on four decades of research at University of Southampton. Title was Journey into Epidemiology, Prevention, Treatment and Osteoporosis |
| Year(s) Of Engagement Activity | 2023 |
| Description | Speech at World Congress on Osteoporosis, Osteoarthritis & Musculoskeletal Diseases (WCO-IOF-ESCEO 2023) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Speech at WCO/IOF in Barcelona |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.wco-iof-esceo.org/ |
| Description | The American Society for Bone and Mineral Research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation The American Society for Bone and Mineral Research |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.asbmr.org/annual-meeting |
| Description | UKRI MyAge launch event (Muscle resilience across the life course: from cells to Society. |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended this event on 24th May 2022 |
| Year(s) Of Engagement Activity | 2022 |
| Description | WHO and Osteoporosis meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended this meeting on 28th June 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | WORLD CONGRESS ON OSTEOPOROSIS, OSTEOARTHRITIS AND MUSCULOSKELETAL DISEASES |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentaiton of IOF Presidents Award |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.wco-iof-esceo.org/ |
| Description | Working group on phosphate disorders ES CEO 2021 (NCH) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Working group vitamin D ESCEO 21 (NCH) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Working group vitamin D ESCEO 21 (NCH) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Working group vitamin D ESCEO 21 (NCH) |
| Year(s) Of Engagement Activity | 2021 |
| Description | online interview |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Nick Fuggle gave an interview about the highlights of the WCO IOF ESCEO meeting i.e. risk prediction, machine learning and computer vision. This was published by touch immunology on 12th June 2023 |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.touchimmunology.com/osteoarthritis/conference-hub/wco-iof-esceo-meeting-highlights-2023-... |