Programme 3: Early development and risk of adult musculoskeletal disease
Lead Research Organisation:
University of Southampton
Department Name: UNLISTED
Abstract
The aim of this programme is to integrate observational epidemiology and mechanistic understanding to inform novel interventions in early life to reduce the risk of later diseases such as osteoporosis and sarcopenia. Whilst our results have already informed national guidelines (DH, NICE, Public Health England and the Scientific Advisory Committee on Nutrition), the programme will advance this work by generating discovery science to delineate underlying mechanisms and to establish the wider relevance of the findings in order to inform the successful implementation of resulting public health strategies.
Technical Summary
Scientific abstract (around 400 words – max. 3,500 characters including spaces) Summary: This programme integrates observational epidemiology and mechanistic understanding to inform novel interventions in early life and thereby to reduce the risk of later diseases such as osteoporosis and sarcopenia.
Objectives: To (a) elucidate risk factors for reduced bone and muscle accrual during growth and development; (b) thus identify potential early interventions aimed at optimizing musculoskeletal development, so maximising peak bone and muscle mass, and; (c) test these
interventions, identifying mechanisms underlying, and markers of, factors which modify efficacy.
Research plan: Our future work will therefore focus on three key areas. First, study of Southampton Women’s Survey (SWS) children in late childhood/adolescence will enable us to characterise patterns of early nutrition and growth in relation to bone mass and body composition, and specifically the potential modifying effect on the pubertal transition of the earlier growth trajectory. Where potential interventions are identified and instruments are available, studies of causal inference may be undertaken using the UK Biobank cohort to inform new randomised controlled trials. We will use novel DXA image-derived phenotypes as part of our Wellcome Trust AUGMENT Award to investigate early life influences on novel indices of adult bone health in UK Biobank. With Programmes 1 and 2, this work will be complemented by novel intergenerational studies in the Hertfordshire Cohort and SWS, assessing phenotype and health across generations. Secondly, we will investigate the replication and persistence of the finding that maternal gestational vitamin D supplementation leads to improved offspring neonatal bone mass amongst winter births, using the SPRING trial (replication) and later childhood follow-up in MAVIDOS (persistence), together with adjunctive analyses in other populations, for example in novel trials such as NiPPeR and HeLTI trials in South Africa, India and China. Lastly, using experimental medicine approaches nested within our larger intervention studies, we will delineate mechanisms by which the impact of our interventions might be maximised, in a precision medicine approach, for example elucidating the influence of genetic polymorphisms on response to vitamin D supplementation and associated bone turnover, and markers of response using epigenetic profiles.
Impact: This programme will enable us to identify new public health approaches to optimise musculoskeletal development into adulthood, and characterise mechanisms underlying/modifying these early developmental influences, to ultimately reduce the burden of musculoskeletal diseases such as osteoporosis and sarcopenia in older age.
Objectives: To (a) elucidate risk factors for reduced bone and muscle accrual during growth and development; (b) thus identify potential early interventions aimed at optimizing musculoskeletal development, so maximising peak bone and muscle mass, and; (c) test these
interventions, identifying mechanisms underlying, and markers of, factors which modify efficacy.
Research plan: Our future work will therefore focus on three key areas. First, study of Southampton Women’s Survey (SWS) children in late childhood/adolescence will enable us to characterise patterns of early nutrition and growth in relation to bone mass and body composition, and specifically the potential modifying effect on the pubertal transition of the earlier growth trajectory. Where potential interventions are identified and instruments are available, studies of causal inference may be undertaken using the UK Biobank cohort to inform new randomised controlled trials. We will use novel DXA image-derived phenotypes as part of our Wellcome Trust AUGMENT Award to investigate early life influences on novel indices of adult bone health in UK Biobank. With Programmes 1 and 2, this work will be complemented by novel intergenerational studies in the Hertfordshire Cohort and SWS, assessing phenotype and health across generations. Secondly, we will investigate the replication and persistence of the finding that maternal gestational vitamin D supplementation leads to improved offspring neonatal bone mass amongst winter births, using the SPRING trial (replication) and later childhood follow-up in MAVIDOS (persistence), together with adjunctive analyses in other populations, for example in novel trials such as NiPPeR and HeLTI trials in South Africa, India and China. Lastly, using experimental medicine approaches nested within our larger intervention studies, we will delineate mechanisms by which the impact of our interventions might be maximised, in a precision medicine approach, for example elucidating the influence of genetic polymorphisms on response to vitamin D supplementation and associated bone turnover, and markers of response using epigenetic profiles.
Impact: This programme will enable us to identify new public health approaches to optimise musculoskeletal development into adulthood, and characterise mechanisms underlying/modifying these early developmental influences, to ultimately reduce the burden of musculoskeletal diseases such as osteoporosis and sarcopenia in older age.
Organisations
- University of Southampton (Lead Research Organisation)
- KK Women and Childrens Hospital, Singapore (Collaboration)
- Southampton City Council (Collaboration)
- UNIVERSITY OF READING (Collaboration)
- University College Dublin (Collaboration)
- Southampton NIHR Biomedical Research Centre in Nutrition (Collaboration)
- University of Sheffield (Collaboration)
- University of Auckland (Collaboration)
- University of the Witwatersrand (Collaboration)
- UNIVERSITY OF BIRMINGHAM (Collaboration)
- Biotechnology and Biological Sciences Research Council (BBSRC) (Collaboration)
- UNIVERSITY OF LIVERPOOL (Collaboration)
- Medical Research Council (MRC) (Collaboration)
- University of Bristol (Collaboration)
- Agency for Science, Technology and Research (A*STAR) (Collaboration)
- University of Manchester (Collaboration)
- Quadram Institute Bioscience (Collaboration)
- University College London (Collaboration)
- UNIVERSITY OF NOTTINGHAM (Collaboration)
- Lancaster University (Collaboration)
- PUBLIC HEALTH ENGLAND (Collaboration)
- National Institute of Health and Medical Research (INSERM) (Collaboration)
- Royal Osteoporosis Society (Collaboration)
- Newcastle University (Collaboration)
- University of South Carolina (Collaboration)
- IMPERIAL COLLEGE LONDON (Collaboration)
- UNIVERSITY OF OXFORD (Collaboration)
- National University of Singapore (Collaboration)
- Erasmus University Rotterdam (Collaboration)
- Edith Cowan University (Collaboration)
- KING'S COLLEGE LONDON (Collaboration)
Publications
Acton RJ
(2021)
The genomic loci of specific human tRNA genes exhibit ageing-related DNA hypermethylation.
in Nature communications
Aggarwal V
(2021)
Opportunistic diagnosis of osteoporosis, fragile bone strength and vertebral fractures from routine CT scans; a review of approved technology systems and pathways to implementation.
in Therapeutic advances in musculoskeletal disease
Al-Daghri NM
(2021)
The application of FRAX in Saudi Arabia.
in Archives of osteoporosis
Albergaria B
(2023)
A new FRAX model for Brazil
in Archives of Osteoporosis
Antoun E
(2022)
Epigenome-wide association study of sarcopenia: findings from the Hertfordshire Sarcopenia Study (HSS).
in Journal of cachexia, sarcopenia and muscle
Antoun E
(2021)
Altered H19/miR-675 expression in skeletal muscle is associated with low muscle mass in community-dwelling older adults
in JCSM Rapid Communications
Ardissino M
(2022)
Pericardial adiposity is independently linked to adverse cardiovascular phenotypes: a CMR study of 42 598 UK Biobank participants.
in European heart journal. Cardiovascular Imaging
Aubert AM
(2022)
Predictors of maternal dietary quality and dietary inflammation during pregnancy: An individual participant data meta-analysis of seven European cohorts from the ALPHABET consortium.
in Clinical nutrition (Edinburgh, Scotland)
Aung N
(2023)
Association of Longer Leukocyte Telomere Length With Cardiac Size, Function, and Heart Failure.
in JAMA cardiology
| Description | Co-authorship of European guidance on osteoporosis in men (ESCEO) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Co-authorship of European position on Real World Evidence in osteoporosis |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Co-authorship of Royal Osteoporosis Society APPG enquiry into FLS (NCH) 2021 |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Co-authorship of Royal Osteoporosis Society APPG enquiry into Primary fracture prevention(NCH) 2022 |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | Co-authorship of Royal Osteoporosis Society APPG enquiry into Primary fracture prevention(NCH) 2022 |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | European guidance on very high fracture risk (NCH, CC) |
| Geographic Reach | Europe |
| Policy Influence Type | Membership of a guideline committee |
| Description | House of Commons launch of A Strategy for Preconception Care |
| Geographic Reach | National |
| Policy Influence Type | Contribution to new or improved professional practice |
| Description | Improving preconception health to prevent ill-health and reduce disparities across generations |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | Maternity Disparities Taskforce Meeting - (KMG 2024) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| URL | https://policymogul.com/key-updates/28287/maternity-disparities-taskforce-meets-to-improve-pre-pregn... |
| Description | National Osteoporosis Guideline Group Advisory Committee (NCH, CC) |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Capital equipment grant (DXA scanner) |
| Amount | £142,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2024 |
| End | 03/2025 |
| Description | Developmental origins of child neurodevelopment: Novel approaches to clinical risk prediction using an international metadataset. |
| Amount | £364,324 (GBP) |
| Funding ID | MR/V029169/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2021 |
| End | 10/2027 |
| Description | Does maternal gestational vitamin D supplementation influence offspring DNA methylation in childhood? |
| Amount | £29,984 (GBP) |
| Funding ID | SGL023\1072 |
| Organisation | Academy of Medical Sciences (AMS) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2020 |
| End | 12/2021 |
| Description | Does pregnancy vitamin D supplementation alter trajectories of body composition and bone mineralisation from early childhood to adolescence? Follow-up of a randomised placebo-controlled trial. |
| Amount | £187,294 (GBP) |
| Funding ID | GN2969 |
| Organisation | Action Medical Research |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2023 |
| End | 06/2026 |
| Description | Does pregnancy vitamin D supplementation alter trajectories of body composition and bone mineralisation from early childhood to adolescence? Follow-up of a randomised placebo-controlled trial. |
| Amount | £187,294 (GBP) |
| Funding ID | GN2969 |
| Organisation | Action Medical Research |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2023 |
| End | 03/2026 |
| Description | Investigating the altered in-utero cellular programming underlying reduced offspring obesity risk following prenatal nutritional supplementation preconception and during pregnancy (KMG 2024) |
| Amount | £45,575 (GBP) |
| Organisation | Southampton NIHR Biomedical Research Centre in Nutrition |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2023 |
| End | 09/2027 |
| Description | MRC National Musculoskeletal Network |
| Amount | £150,847 (GBP) |
| Funding ID | MC_PC_21022 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2022 |
| End | 02/2024 |
| Description | NIHR Clinical Lectureship |
| Amount | £250,000 (GBP) |
| Funding ID | CL-2020-26-002 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2021 |
| End | 11/2026 |
| Description | NIHR Southampton BRC Development of mother-offspring multi'omic "handprints" that predict child phenotypes - KMG 2023 |
| Amount | £90,108 (GBP) |
| Organisation | NIHR Southampton Biomedical Research Centre |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 08/2022 |
| End | 08/2026 |
| Description | NIHR Southampton BRC PhD studentship |
| Amount | £70,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2024 |
| End | 09/2027 |
| Description | Nestle (Global) - NiPPeR Microbiome analysis - KMG 2023 |
| Amount | $547,560 (SGD) |
| Organisation | Nestlé (Global) |
| Sector | Private |
| Country | Switzerland |
| Start | 12/2022 |
| End | 12/2023 |
| Description | Nestle (Global) HMO and neurodevelopment - KMG 2023 |
| Amount | $72,924 (SGD) |
| Organisation | Nestlé (Global) |
| Sector | Private |
| Country | Switzerland |
| Start | 09/2022 |
| End | 12/2023 |
| Description | Nutritional determinants of skeletal development and bone loss: an investigation using a novel computer vision assessment of bone microarchitecture |
| Amount | £36,000 (GBP) |
| Organisation | University of Southampton |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 08/2022 |
| End | 09/2025 |
| Description | PhD studentship (Computer vision in bone develoment) |
| Amount | £35,000 (GBP) |
| Organisation | University of Southampton |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 09/2022 |
| End | 10/2025 |
| Description | Preventing broken bones in older people: from research to policy to practice |
| Amount | £29,566 (GBP) |
| Funding ID | MRF-145-0011-DG-HARV-C0913 |
| Organisation | Medical Research Council (MRC) |
| Department | Medical Research Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 09/2022 |
| Description | Why and how AAC develops and how can we prevent this? |
| Amount | $1,202,213 (AUD) |
| Organisation | Medical Research Future Fund |
| Sector | Public |
| Country | Australia |
| Start | 09/2023 |
| End | 10/2026 |
| Title | Dataset for paper :Maternal and fetal genetic variation in vitamin D metabolism and umbilical cord blood 25-hydroxyvitamin D - Supplemental Tables and Figures |
| Description | Supplemental tables and figures to accompany the paper "Maternal and fetal genetic variation in vitamin D metabolism and umbilical cord blood 25-hydroxyvitamin D" by RJ Moon, LDF Cooke, S D'Angelo, EM Curtis, P Titcombe, JH Davies, KM Godfrey, JK Cleal, RM Lewis, C Cooper & NC Harvey |
| Type Of Material | Database/Collection of data |
| Year Produced | 2022 |
| Provided To Others? | Yes |
| Impact | Supplemental tables and figures to accompany the paper "Maternal and fetal genetic variation in vitamin D metabolism and umbilical cord blood 25-hydroxyvitamin D" by RJ Moon, LDF Cooke, S D'Angelo, EM Curtis, P Titcombe, JH Davies, KM Godfrey, JK Cleal, RM Lewis, C Cooper & NC Harvey |
| URL | https://eprints.soton.ac.uk/455706/ |
| Title | SPRING Trial |
| Description | SPRING Trial |
| Type Of Material | Database/Collection of data |
| Year Produced | 2021 |
| Provided To Others? | No |
| Impact | SPRING Trial |
| Description | ALPHABET |
| Organisation | Erasmus University Rotterdam |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | National Institute of Health and Medical Research (INSERM) |
| Department | Center for Epidemiological and Bio Statistics Research at Sorbonne |
| Country | France |
| Sector | Public |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | University College Dublin |
| Department | School of Physics |
| Country | Ireland |
| Sector | Academic/University |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | University College Dublin |
| Country | Ireland |
| Sector | Academic/University |
| PI Contribution | WP5, bone outcomes |
| Collaborator Contribution | Consortium |
| Impact | Ongoing |
| Start Year | 2017 |
| Description | ALPHABET |
| Organisation | University of Bristol |
| Department | Biomedical Research Unit in Nutrition, Diet and Lifestyle |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | WP5, bone outcomes |
| Collaborator Contribution | Consortium |
| Impact | Ongoing |
| Start Year | 2017 |
| Description | ALPHABET |
| Organisation | University of South Carolina |
| Department | Arnold School of Public Health |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | AUGMENT UK Biobank collaboration |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | AUGMENT UK Biobank collaboration |
| Collaborator Contribution | AUGMENT UK Biobank collaboration |
| Impact | AUGMENT UK Biobank collaboration |
| Start Year | 2017 |
| Description | AUGMENT UK Biobank collaboration |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | AUGMENT UK Biobank collaboration |
| Collaborator Contribution | AUGMENT UK Biobank collaboration |
| Impact | AUGMENT UK Biobank collaboration |
| Start Year | 2017 |
| Description | Abdominal Aortic Calcification Collaboration |
| Organisation | Edith Cowan University |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Collaboration using AI techniques to detect abdominal aortic calcification. Collaboration between Edith Cowan University and University of Western Australia; McMaster University; University of Manitoba; University of Southampton. Southampton providing UK biobank expertise. |
| Collaborator Contribution | Collaboration using AI techniques to detect abdominal aortic calcification. Collaboration between Edith Cowan University and University of Western Australia; McMaster University; University of Manitoba; University of Southampton. Southampton providing UK biobank expertise. |
| Impact | Ongoing |
| Start Year | 2021 |
| Description | BBSRC Lifeourse Diet and Health Open Innovation Research Club |
| Organisation | Quadram Institute Bioscience |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Leadership team for this UKRI-Hub award with the Quadram Institute and the Universities of Reading, Cambridge and Leeds, working with 12 industry partners |
| Collaborator Contribution | Successful grant application, now establishing specific collaborations with industry partners |
| Impact | Initial industry partnership Research Cafe event planned for May 2023 |
| Start Year | 2022 |
| Description | BBSRC Lifeourse Diet and Health Open Innovation Research Club |
| Organisation | University of Reading |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Leadership team for this UKRI-Hub award with the Quadram Institute and the Universities of Reading, Cambridge and Leeds, working with 12 industry partners |
| Collaborator Contribution | Successful grant application, now establishing specific collaborations with industry partners |
| Impact | Initial industry partnership Research Cafe event planned for May 2023 |
| Start Year | 2022 |
| Description | Collaborative preconception research - HELMS |
| Organisation | KK Women and Childrens Hospital, Singapore |
| Country | Singapore |
| Sector | Hospitals |
| PI Contribution | Collaboration to develop the study protocol for Healthy Early Life Moments in Singapore (HELMS), a single-arm pilot implementation model |
| Collaborator Contribution | Collaboration to develop the study protocol for Healthy Early Life Moments in Singapore (HELMS), a single-arm pilot implementation model |
| Impact | Multi-disciplinary obstetrics & public health |
| Start Year | 2021 |
| Description | Collaborative research with the Singapore S-PRESTO study team |
| Organisation | Agency for Science, Technology and Research (A*STAR) |
| Department | Singapore Institute for Clinical Sciences |
| Country | Singapore |
| Sector | Academic/University |
| PI Contribution | Collaborative research within the Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO), a preconception, longitudinal cohort study that aims to study the effects of nutrition, lifestyle, and maternal mood prior to and during pregnancy on the epigenome of the offspring and clinically important outcomes including duration of gestation, fetal growth, metabolic and neural phenotypes in the offspring. |
| Collaborator Contribution | Collaborative research within the Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO), a preconception, longitudinal cohort study that aims to study the effects of nutrition, lifestyle, and maternal mood prior to and during pregnancy on the epigenome of the offspring and clinically important outcomes including duration of gestation, fetal growth, metabolic and neural phenotypes in the offspring. |
| Impact | Research publications |
| Start Year | 2021 |
| Description | Early LifeLab |
| Organisation | Southampton City Council |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Early LifeLab is an educational intervention for primary schools. It aims to support children in making healthy choices about the foods they eat, their levels of physical activity and sedentary pursuits, and their sleep patterns. Early LifeLab provides a series of fully resourced, short, cross-curricular work packages for delivery at different stages of the primary years. It makes the science behind the need for healthy diet, physical activity and sleep accessible to young children, helping them to discover why this matters for themselves. |
| Collaborator Contribution | The innovative programme has been awarded £200,000 by Southampton City Council to fund key work over the next three years. |
| Impact | Evaluation will be undertaken through a PhD studentship awarded by the NIHR BRC |
| Start Year | 2022 |
| Description | Impact of paternal obesity on offspring brain structure and function; implications for Alzheimer's disease |
| Organisation | Lancaster University |
| Department | Faculty of Health and Medicine |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-applicant on research award from Alzheimer's Research UK |
| Collaborator Contribution | Successful application for research funding |
| Impact | No outputs as yet |
| Start Year | 2023 |
| Description | LifeLab Soweto |
| Organisation | University of the Witwatersrand |
| Department | Wits Reproductive Health and HIV Institute |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Collaboration to design, develop, deliver and evaluate an educational intervention in Soweto as part of a strategy to support the wellbeing of young people and their families. |
| Collaborator Contribution | Collaboration to design, develop, deliver and evaluate an educational intervention in Soweto as part of a strategy to support the wellbeing of young people and their families. |
| Impact | Multi-disciplinary health and education |
| Start Year | 2021 |
| Description | LifeLab Soweto |
| Organisation | University of the Witwatersrand |
| Country | South Africa |
| Sector | Academic/University |
| PI Contribution | Collaboration to design, develop, deliver and evaluate an educational intervention in Soweto as part of a strategy to support the wellbeing of young people and their families. |
| Collaborator Contribution | Collaboration to design, develop, deliver and evaluate an educational intervention in Soweto as part of a strategy to support the wellbeing of young people and their families. |
| Impact | Multi-disciplinary health and education |
| Start Year | 2021 |
| Description | MAVIDOS Childhood Follow up |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Recruitment to MAVIDOS 6 year follow-up in Sheffield |
| Collaborator Contribution | Recruitment to MAVIDOS six-year follow-up in Sheffield |
| Impact | N/A |
| Start Year | 2016 |
| Description | MAVIDOS Childhood Follow-up Oxford |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Recruitment of children to MAVIDOS six-year follow-up in Oxford |
| Collaborator Contribution | Recruitment of children to MAVIDOS six-year follow-up in Oxford |
| Impact | N/A |
| Start Year | 2016 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | Newcastle University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Birmingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Liverpool |
| Department | School of Medicine Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Nottingham |
| Department | School of Biology Nottingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | MRC National Musculoskeletal Ageing Network |
| Organisation | University of Sheffield |
| Department | Sheffield Biorepository |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres. |
| Collaborator Contribution | Development of novel strategy to address frailty transition in older age |
| Impact | Publish strategy paper, workshops, seminars, grant applications. |
| Start Year | 2022 |
| Description | Microbial derived metabolomics collaboration |
| Organisation | Southampton NIHR Biomedical Research Centre in Nutrition |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Concept to measure microbial derived metabolomics and relate these to infantile atopic dermatitis |
| Collaborator Contribution | Mass spectrometry and metabolomics expertise |
| Impact | Application for an Academy of Medical Sciences Starter Grant for Clinical Lecturers |
| Start Year | 2021 |
| Description | Nutritional Intervention Preconception and During Pregnancy to Maintain Healthy Glucose Metabolism & OffspRing Health ("NiPPeR" trial) |
| Organisation | National University of Singapore |
| Country | Singapore |
| Sector | Academic/University |
| PI Contribution | Collaborative partnership for preconception double blind multicentre randomised controlled trial |
| Collaborator Contribution | Protocol development, participant recruitment and biosample collection |
| Impact | Publication of protocol in BMC Trials, of the primary outcome in Diabetes Care, and of multiple pre-specified secondary outcomes |
| Start Year | 2014 |
| Description | Nutritional Intervention Preconception and During Pregnancy to Maintain Healthy Glucose Metabolism & OffspRing Health ("NiPPeR" trial) |
| Organisation | University of Auckland |
| Country | New Zealand |
| Sector | Academic/University |
| PI Contribution | Collaborative partnership for preconception double blind multicentre randomised controlled trial |
| Collaborator Contribution | Protocol development, participant recruitment and biosample collection |
| Impact | Publication of protocol in BMC Trials, of the primary outcome in Diabetes Care, and of multiple pre-specified secondary outcomes |
| Start Year | 2014 |
| Description | Preconception partnership |
| Organisation | King's College London |
| Department | Women's Health Academic Centre |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The Preconception Partnership was jointly formed by my research team and researchers from UCL and King's College London, working with Public Health England. In 2022 Keith Godfrey became Co-Chair of the Partnership |
| Collaborator Contribution | The Preconception Partnership was jointly formed by my research team and researchers from UCL and King's College London, working with Public Health England. |
| Impact | The Preconception Partnership is a coalition of groups representing different aspects of preconception health in women and their partners, including the UK's acknowledged experts in the fields of reproductive and sexual health, obstetrics and gynaecology, population health and epidemiology, nutritional sciences, behavioural sciences and education in schools. We advocate policy that acknowledges the opportunities and challenges of health promotion at this time in the life course, and offer the leadership necessary to turn such policies into coordinated, practical and effective action. The work of the partnership led Public Health England to publish new guidance in 2018 ("Preconception care: making the case"), which includes information, intelligence, and tools with evidence-based approaches for the embedding of preconception care. Working with the government Office for Health Improvement and Disparities the partnership has enabled routine publication of preconception health statistics as part of the OHID Public health profile ("Fingertips") reporting. |
| Start Year | 2018 |
| Description | Preconception partnership |
| Organisation | Public Health England |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | The Preconception Partnership was jointly formed by my research team and researchers from UCL and King's College London, working with Public Health England. In 2022 Keith Godfrey became Co-Chair of the Partnership |
| Collaborator Contribution | The Preconception Partnership was jointly formed by my research team and researchers from UCL and King's College London, working with Public Health England. |
| Impact | The Preconception Partnership is a coalition of groups representing different aspects of preconception health in women and their partners, including the UK's acknowledged experts in the fields of reproductive and sexual health, obstetrics and gynaecology, population health and epidemiology, nutritional sciences, behavioural sciences and education in schools. We advocate policy that acknowledges the opportunities and challenges of health promotion at this time in the life course, and offer the leadership necessary to turn such policies into coordinated, practical and effective action. The work of the partnership led Public Health England to publish new guidance in 2018 ("Preconception care: making the case"), which includes information, intelligence, and tools with evidence-based approaches for the embedding of preconception care. Working with the government Office for Health Improvement and Disparities the partnership has enabled routine publication of preconception health statistics as part of the OHID Public health profile ("Fingertips") reporting. |
| Start Year | 2018 |
| Description | Preconception partnership |
| Organisation | University College London |
| Department | Institute for Women's Health |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The Preconception Partnership was jointly formed by my research team and researchers from UCL and King's College London, working with Public Health England. In 2022 Keith Godfrey became Co-Chair of the Partnership |
| Collaborator Contribution | The Preconception Partnership was jointly formed by my research team and researchers from UCL and King's College London, working with Public Health England. |
| Impact | The Preconception Partnership is a coalition of groups representing different aspects of preconception health in women and their partners, including the UK's acknowledged experts in the fields of reproductive and sexual health, obstetrics and gynaecology, population health and epidemiology, nutritional sciences, behavioural sciences and education in schools. We advocate policy that acknowledges the opportunities and challenges of health promotion at this time in the life course, and offer the leadership necessary to turn such policies into coordinated, practical and effective action. The work of the partnership led Public Health England to publish new guidance in 2018 ("Preconception care: making the case"), which includes information, intelligence, and tools with evidence-based approaches for the embedding of preconception care. Working with the government Office for Health Improvement and Disparities the partnership has enabled routine publication of preconception health statistics as part of the OHID Public health profile ("Fingertips") reporting. |
| Start Year | 2018 |
| Description | ROS MRF APPG collaboration |
| Organisation | Royal Osteoporosis Society |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Collaboration on developing policy for primary fracture prevention with Royal Osteoporosis Society, University of Southampton and University of Sheffield |
| Collaborator Contribution | Collaboration on developing policy for primary fracture prevention with Royal Osteoporosis Society, University of Southampton and University of Sheffield |
| Impact | As per publications and APPG report |
| Start Year | 2022 |
| Description | ROS MRF APPG collaboration |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Collaboration on developing policy for primary fracture prevention with Royal Osteoporosis Society, University of Southampton and University of Sheffield |
| Collaborator Contribution | Collaboration on developing policy for primary fracture prevention with Royal Osteoporosis Society, University of Southampton and University of Sheffield |
| Impact | As per publications and APPG report |
| Start Year | 2022 |
| Description | UKRI (BBSRC/MRC) UK Ageing Network |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | MyAge (Muscle resilience across the life course: from cells to society) UKRI network - member of leadership team |
| Collaborator Contribution | MyAge (Muscle resilience across the life course: from cells to society) network |
| Impact | Media communication at launch: https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page |
| Start Year | 2022 |
| Description | UKRI (BBSRC/MRC) UK Ageing Network |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MyAge (Muscle resilience across the life course: from cells to society) UKRI network - member of leadership team |
| Collaborator Contribution | MyAge (Muscle resilience across the life course: from cells to society) network |
| Impact | Media communication at launch: https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page |
| Start Year | 2022 |
| Description | UKRI (BBSRC/MRC) UK Ageing Network |
| Organisation | Medical Research Council (MRC) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | MyAge (Muscle resilience across the life course: from cells to society) UKRI network - member of leadership team |
| Collaborator Contribution | MyAge (Muscle resilience across the life course: from cells to society) network |
| Impact | Media communication at launch: https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page |
| Start Year | 2022 |
| Description | UKRI (BBSRC/MRC) UK Ageing Network |
| Organisation | University of Birmingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MyAge (Muscle resilience across the life course: from cells to society) UKRI network - member of leadership team |
| Collaborator Contribution | MyAge (Muscle resilience across the life course: from cells to society) network |
| Impact | Media communication at launch: https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page |
| Start Year | 2022 |
| Description | UKRI (BBSRC/MRC) UK Ageing Network |
| Organisation | University of Nottingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | MyAge (Muscle resilience across the life course: from cells to society) UKRI network - member of leadership team |
| Collaborator Contribution | MyAge (Muscle resilience across the life course: from cells to society) network |
| Impact | Media communication at launch: https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page |
| Start Year | 2022 |
| Title | CE Marked kit for COVID-19 saliva testing |
| Description | CE Marked kit for COVID-19 saliva testing |
| Type | Diagnostic Tool - Non-Imaging |
| Current Stage Of Development | Market authorisation |
| Year Development Stage Completed | 2022 |
| Development Status | Under active development/distribution |
| Impact | Reduced community COVID transmission and increased school attendance at the height of the second COVID wave |
| Title | MAVIDOS trial vitamin D intervention |
| Description | Vitamin D supplementation |
| Type | Preventative Intervention - Nutrition and Chemoprevention |
| Current Stage Of Development | Wide-scale adoption |
| Year Development Stage Completed | 2021 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | Maternal vitamin D supplementation led to greater bone mass in the offspring for winter births |
| Title | SPRING Pregnancy vitamin D supplementation trial |
| Description | Trial of vitamin D supplementation during pregnancy |
| Type | Preventative Intervention - Nutrition and Chemoprevention |
| Current Stage Of Development | Wide-scale adoption |
| Year Development Stage Completed | 2021 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | Trial of vitamin D supplementation during pregnancy |
| Description | 114th Annual Meeting of the Association of Physicians |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this online meeting on 16th March 2021. This was a APAM online Inauguration. The meeting was hosted by University of Oxford. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://aopgbi.org/ |
| Description | 8th IOF Asia Pacific Regional Conference Programme, IOF Regional Bangkok |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this conference, and gave a talk entitled 'Osteoporosis Management in 2021: South Asia meets Europe'. This took place on 1st December 2021. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.iof-regional.org |
| Description | A talk at CIMA/CMAR Joint Meeting, Birmingham |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | CIMA/CMAR Network Meeting/Presentation |
| Year(s) Of Engagement Activity | 2023 |
| Description | ASBMR online (EC) 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at ASBMR, USA |
| Year(s) Of Engagement Activity | 2021 |
| Description | ASBMR-ECTS debate EC 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | ASBMR-ECTS debate EC 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Abstract Writing Masterclass |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Nick Harvey presented the MRC National Musculoskeletal Ageing Network abstract writing seminar, which took place on December 13th 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Academy Advisory Committee Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 21st April 2021. The meeting was attended by over 10 people. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.theros.org.uk |
| Description | Almost half of six-year-olds are not active enough |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Press release relating to our publication - A study with families in Southampton found 47 percent of six-year-olds did not meet the recommended daily guidelines for physical activity. The study was carried out pre-pandemic by researchers at the universities of Southampton and Cambridge. All families who took part were involved in the ongoing Southampton Women's Survey. Children who are active are more likely to be active adults, reducing their risk of obesity and many lifestyle-related diseases later in life. They need to be active for their muscles and bones to develop properly. Being active also improves their ability to concentrate, boosts their mood and leads to better educational performance at school. Yet the results from this study, published in the Journal of Physical Activity & Health, suggest almost half of children are not active enough. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.southamptonbrc.nihr.ac.uk/post/almost-half-of-six-year-olds-not-active-enough |
| Description | Article for University of Southampton Medically Speaking Blog |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Article witten for Medically Speaking Blog, University of Southampton |
| Year(s) Of Engagement Activity | 2023 |
| Description | Article written by Nick Harvey in UoS Enews |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Nick Harvey wrote an article for the University of Southampton Enews in which he wrote about the welcome return to face-face- meetings; the opportunity for in-person participation in the American Society for Bone and Mineral Research Annual Scientific Conference in Austin, Texas and to be able to catch up with colleagues and friends from all over the world. He also mentioned that the new term brings progression of a major initiative in UK musculoskeletal science with the consolidation of the strategic framework for our UKRI MRC National Musculoskeletal Ageing Network. The network will be led by the University of Southampton. He also added that it was great to see the exciting news of the UK Biobank Repeat Imaging Study recently made public. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Association for the Study of Obesity national webinar |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | "Maternal obesity and the health of the next generation", invited keynote speaker |
| Year(s) Of Engagement Activity | 2021 |
| Description | BRC Science Forum Friday |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | During the current pandemic, NIHR Southampton Biomedical Research Centre hold a weekly forum to discuss the latest research. All staff with a University of Southampton login to Teams can access the recordings of these talks. Cyrus Cooper gave his talk on Lifecourse Epidemiology of Musculoskeletal Disorders on 12th January 2021. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://web.microsoftstream.com/video/0cd14716-d313-4398-b541-52df9e72aa54?referrer=https:%2F%2Fwww.... |
| Description | BRC Science Forum Friday KMG 2021 - KMG 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | At the BRC Science Forum Friday Professor Keith Godfrey gave a presentation from 1.30 - 2.00 p.m. This presentation was an idea for the proposed BRC Research themes for the next BRC application 2022 - 2027. |
| Year(s) Of Engagement Activity | 2021 |
| Description | BRS ECTS Liverpool |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speech at BRS ECTS Liverpool |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://boneresearchsociety.org/meetings/198/ |
| Description | BSRA MRC National Musculoskeletal Ageing Network joint symposium 2023 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | BSRA MRC National Musculoskeletal Ageing Network joint symposium 2023 |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://bsra.org.uk/events/bsra-asm-2023/ |
| Description | Blog |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cyrus Cooper discussed how and why we should preserve creativity in times of crisis on both a personal and professional level. Blog attached. Blog was called Medically speaking. |
| Year(s) Of Engagement Activity | 2021 |
| Description | COVID-19 RT-LAMP testing has high accuracy in individuals with and without symptoms |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Press release relating to multisite clinical evaluation published in the Journal of Molecular Diagnostics, which defined the clinical performance of the RT-LAMP assay for COVID-19 testing using saliva and swabs, both directly (Direct RT-LAMP) on the sample and after extraction of the viral RNA (RNA RT-LAMP). The "real world" evaluation of an improved sample preparation method for direct RT-LAMP testing for detection of COVID-19 conducted by NHS Trusts and universities demonstrated high accuracy in individuals with and without symptoms. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.southampton.ac.uk/news/2022/01/lamp-testing-accuracy.page |
| Description | Centre of Excellence Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 7th June 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Chair ASBMR IOF joint session at ASBMR 2021 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chair ASBMR IOF joint session at ASBMR 2021 (NCH) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Childhood obesity linked with mother's unhealthy diet before pregnancy |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Press release - New research led by the University of Southampton shows supporting women to eat a healthy diet pre-pregnancy could reduce risk of obesity for their children. Rates of childhood obesity are increasing worldwide. In the UK, nearly a quarter of under-fives are overweight or obese. This increases to more than a third by the time children start secondary school. Children who are obese are more likely to be obese adults, with long-term consequences for their health. Unhealthy diets are an important factor that contribute to this. Research, led by Southampton's Dr Sarah Crozier, has found children aged eight or nine were more likely to be obese if their mother had a poor diet during - and before - pregnancy. The research identifies these as critical times, when initiatives to reduce childhood obesity may be more effective. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.southamptonbrc.nihr.ac.uk/post/childhood-obesity-linked-with-mother-s-unhealthy-diet-bef... |
| Description | DOHAD Conference 2022 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended the DOHAD International Conference. This was held between 27th-31st August 2022. Over 1,000 people attended. |
| Year(s) Of Engagement Activity | 2022 |
| Description | DOHAD Society webinar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | DOHAD Society webinar |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://dohadsoc.org/webinars/ |
| Description | EAG teleconference: Osteoporosis and Fragility Fractures Policy Network |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 16th September. The meeting was called 'ASBMR Secondary Fracture Prevention Initiative, Full Coalition Call' |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.osteopolicynetwork.org |
| Description | ECTS 2021 Congress |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper gave a presentation entitled: 'Building Bones in Young Individuals' at the ECTS 2021 Congress. This was attended by over 100 people. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.ects2021.org |
| Description | ESCEO Working Group |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended the ESCEO Working Group on September 9th 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | European Geriatric Medical Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | speech/presentation for EUGMS |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://eugms2023.com/ |
| Description | Evaluation of the expanded Southampton pilot study (Phase 2) for use of saliva-based lamp testing in asymptomatic populations KMG 2021 - KMG 2022 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | The University News wrote about the report published on the evaluation of the expanded Southampton pilot study (Phase 2) for use of saliva-based lamp testing in asymptomatic populations. Final report 16th November 2020. The lead author of this report was Professor Keith Godfrey, Professor Janis Baird and Professor Mary Barker were also authors. The title of the article was "Southampton pilot demonstrates effective COVID-19 testing in school and University settings. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://doi.org/10.5258/SOTON/P0045 |
| Description | FRAX Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attending a FRAX meeting, held by University of Sheffield on 4th March 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Fellowship Committee Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended this meeting on 10th May 2021. There were over 100 people in attendance. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.acmedsci.ac.uk |
| Description | Gestational vitamin D supplementation: observation mechanism and intervention in the MAVIDOS trial. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Nick Harvey gave a talk at the BSR Science Forum on 18th February 2022. Up to 50 people attended. |
| Year(s) Of Engagement Activity | 2022 |
| Description | IOF symposium at DVO Congress, Salzburg |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | IOF at DVO conference |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.emedevents.com/c/medical-conferences-2023/annual-congress-dvo-osteology-2023 |
| Description | International Venice Forum: Why investing in Maternal, Newborn and Child Health (MNCH) is critical for sustainable recovery after COVID-19 - KMG 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Keith Godfrey gave a presentation during Theme E entitled "Test, Trace and Learn - Lessons from the COVID 19 pandemic that will guide further public health preparedness and inform health policy research going forward. there were over 100 paticipants from 40 countries taking part in this International Venice Forum: Why investing in Maternal, Newborn and Child Health (MNCH) is critical for sustainable recovery after COVID-19 |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.fisv.org/wp-content/uploads/2021/03/Draft-Programme-Venice-MNCH-Forum.pdf |
| Description | Interview Rosemary Lobley of HEQ |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper gave an interview to Rosemary Lobley of HEQ about Osteoporosis, diagnosis, prevention, and treatment. The article is from issue 16 of Health Europa. The date of the interview was 17th February 2021. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.healtheuropa.eu/osteoporosis-diagnosis-prevention-and-treatment/105953/ |
| Description | Invited Chair joint IOF SIBOMM session (NCH) 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited Chair joint IOF SIBOMM session (NCH) 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Invited presentation BRADOO 2021 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited presentation BRADOO 2021 (NCH) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Invited presentation at Belgian Bone Club 2022 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited presentation at Belgian Bone Club 2022 (NCH) |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited presentation at SICOT (NCH) 21 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited presentation at SICOT (NCH) 21 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Launch of WHO-ESCEO |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Nick Harvey attended the launch of this event in Geneva, Switzerland on 23rd February 2023. There were over 1,000 attendees. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Launch of the MRC Lifecourse Epidemiology Centre & MRC National Musculoskeletal Group |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | The launch of the MRC Lifecourse Epidemiology Centre and the MRC National Musculoskeletal Ageing Network was an online event. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://us06web.zoom.us/rec/play |
| Description | Lay presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Nick Harvey delivered a lay presentation on Osteoporosis to the Patient Partner Group at the St Francis Surgery in Hedge End, Southampton. Around 100 people attended. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Lecture at BRS Conference Oxford |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper gave a lecture entitled 'Fracture Epidemiology Across the Globe'. This took place on 28th June 2021. Over 100 people attended. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.boneresearchsociety.org |
| Description | LifeLab Online |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | Development of online scientific literacy & engagement resources, including relating to COVID-19 testing and transmission |
| Year(s) Of Engagement Activity | 2021 |
| Description | Lister Prize Interviews |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attending this event on 19th May 2021. |
| Year(s) Of Engagement Activity | 2021 |
| Description | MRC National Musculoskeletal Ageing Network ECR/MCR developmental sessions |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | MRC National Musculoskeletal Ageing Network ECR/MCR developmental sessions |
| Year(s) Of Engagement Activity | 2022 |
| Description | MRC National Musculoskeletal Ageing Network Seminars |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | MRC National Musculoskeletal Ageing Network Seminars |
| Year(s) Of Engagement Activity | 2022 |
| Description | MTP WCO (EC) 2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Meet The Expert session at World Congress and Osteoporosis |
| Year(s) Of Engagement Activity | 2021 |
| Description | MTP WCO 2021 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Meet The Professor session at World Congress in Osteoporosis 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Media Attention for paper published in PLoS Medicine Maternal B-vitamin and vitamin D (KMG 2024) |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Godfrey KM, Titcombe P, El-Heis S, Albert BB, Huiwen Tham E, Barton SJ, Kenealy T, Foong-Fong Chong M, Nield H, Chong YS, Chan S-Y, Cutfield W.S, Nipper Study Group. Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial. PLOS Medicine. Https://doi.org/10.137/journal.pmed.1004260 December 5 2023. UoS Media report gave media stats showing this paper reached 96 media outlets worldwide, 40 UK newspapers and TV/radio, it was published by media in Europe, the USA, Canada, India, China and Africa. More than 10 million people saw it globally. It was published by The Guardian, The Times, the Daily Mail and the Independent. There was a Science Media Centre Brieifing with two academic responses to the paper with comments used by six newspapers. Internet; Social Media (Facebook 2121, LInkedIn 2,501, X previously twitter 1,753 reaching 6,269 people) |
| Year(s) Of Engagement Activity | 2023 |
| Description | Media attention for published paper Br J Dermatology 2022;187:659-66 - KMG 2023 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | El Heis S, D'Angelo S, Curtis EM, Healy E, Moon RJ, Crozier SR, Inskip H, Cooper C, Harvey NC, Godfrey KM and the MAVIDOS Trial Group. Maternal antenatal vitamin D supplementation and offspring risk of atopic eczema in the first 4 years of life: evidence from a randomized controlled trial. British Journal of Dermatology. 2022;187:659-666. This paper received a lot of media attention from numerous outlets, including 29 websites and 54 social media platforms. It was in the top 5% of all research outputs scored by Almetric. Articles included a write up in the magazine Mother.ly, The University of Southampton News page and numerous others details of which are attached. |
| Year(s) Of Engagement Activity | 2022 |
| Description | MyAge London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | MyAge published a roadmap to help shape the future of muscle resilience research |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.ukanet.org.uk/myage/news-events/ |
| Description | NIH Strategic Workshop, Preconceptional Origins of Child Health Outcomes |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | "Preconception nutrition to optimise offspring life chances", Invited Keynote Speaker |
| Year(s) Of Engagement Activity | 2021 |
| Description | Nutrition Society Summer Meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited keynote speaker "Maternal preconception nutrition and the life chances of the next generation" |
| Year(s) Of Engagement Activity | 2021 |
| Description | Online Presentation |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Nick Harvey gave an online presentation for USA BoneECHO on 28th January 2023. This was attended by over 1,000 people. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Pagets Information Day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper gave the Introduction speech at the Pagets Information day on 8th October 2021. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Participant in Committee Meeting HDR UK QQR Research Driver Programmes Sub-committee meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper was part of this meeting which took place on 25 May 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Presentation at 3rd World Congress on Maternal Neonatal Medicine - KMG 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Keith Godfrey gave a presentation entitled Periconceptional stressors at the 3rd World Congress on Maternal Neonatal Medicine. There were 1640 participants from 88 countries at this event. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.mcascientificevents.eu/worldmfnm/ |
| Description | Presentation at BSR (EC) 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at British Society for Rheumatology |
| Year(s) Of Engagement Activity | 2021 |
| Description | Presentation at Prizegiving event |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper presented a prize at the Rank Prize 50th Anniversary event. This took place on 4th July 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Presentation at WCO 2021 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at World Congress in Osteoporosis 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Presentations at WCO (EC) 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at World Congress in osteoporosis |
| Year(s) Of Engagement Activity | 2021 |
| Description | Press Release "Reduce risk of childhood obesity thrugh good nutrition before and during pregnancy says scientists" (KMG 2024) |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | An article relating to Lyons-Reid J, Derraik JGB, Kennealy T, Albert BB, Nieves MR, Monnard CR, Titcombe P, Nield H, Barton SJ, El-Heis S, Tham E, Godrey KM, Chan S-Y, Cutfield WS, Nipper Study Group. Impact of preconception and antenatal supplementation with myo-inositol, probiotics, and micronurients on offspring BMI and weight gain over the first 2 years. BMC Medicine 2024 22:39 entitled "Reduce risk of childhood obesity through good nutrition before and during pregnancy, says scientists" appeared in the University of Southampton News, and ENews, it was also mentioned by NIHR and Medical Daily. |
| Year(s) Of Engagement Activity | 2024 |
| Description | Press Release and Publicity - findings from the NIPPER study - SB & KMG 2021 - KMG 2022 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | This publication (Godfrey K, Barton SJ, El-Heis S, Kenealy T, Nield H, Baker PN, Chon YS, Cutfield W, Chan S-Y, Nipper Study Group. Myo-Inositol,probioticsand microntrient supplementation from preconception for glycemia in pregnancy: NiPPeR International Multicenter Double-Blind Ramdomised Controlled Trial. Diabetes Care published online 29 March 2021 doi;.org/10.2337/dc20-2515.) of the findings from the NiPPeR study in this paper received some publicity from both Nestle and Food in Progress as well as being reported by the University of Southampton. The findings show that a mother's diet before and during pregnancy is important for herself and gives her baby the best start in life. The supplementation given to the women taking part in the NiPPeR study was linked to reduced risk of pre-term birth. The publication can be found at: https://www.foodinprogress.com/study-links-nutritional-supplementation-taken-preconception-and-in-pregnancy-to-a-reduced-risk-of-preterm-birth/; |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.southampton.ac.uk/news/2021/03/nipper-trial-reduced-preterm-birth.page |
| Description | Press Release and publication of paper |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Press release for the paper entitled "Is the skull responsive to bone mineralisation stimuli in children? published in the journal Bone. There was some media attention following the publication of this paper. The press release was entitled "Skulls stay strong despite worse diets" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Press Release of published paper |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | There were a number of online citings following a press release entitled "Three coffees a day could help keep the doctor away." This was to do with an article published in European Journal of Preventive Cardiology entitled: Light to moderated coffee consumption is associated with lower risk of death: UK Biobank Study. Simon J, Fung K, et al. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Press release for published paper |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | A press release came out on 12th August 2022 for the paper entitled "Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability - results from the Women's Health Initiative hormone therapy trials." The paper was published in Osteoporosis International. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Preventing broken bones in older people: from research to policy to practice |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | The University Faculty of Medicine print a Research Roundup Newsletter. These newsletters aim to celebrate success, provide research updates and give information on upcoming opportunities. The second of these newsletters was written by Professor Nick Harvey. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Public engagement session on osteoporosis with primary care patients |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Speech on Osteoporosis to St Thomas's Practice |
| Year(s) Of Engagement Activity | 2019,2023 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 23rd December 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 19th May 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 28th January 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 21st October 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 13th May 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 19th April 2021, as an Impact Assessor |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 1st September 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 18th June 2021. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 31st August 2021, as a Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 21st October 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on May 4th 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 19th November 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 21st September 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 18th & 19th August 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attending a REF meeting on 17th March 2021, as an Impact Assesor |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 28th April 2021, as an Impact Assessor. |
| Year(s) Of Engagement Activity | 2021 |
| Description | REF Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 16th July 2021. |
| Year(s) Of Engagement Activity | 2021 |
| Description | ROS APPG Report |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Royal Osteoporosis Society All Party Parliamentary Group in Osteoporosis Enquiry into primary fracture prevention, partly supported by MRF grant |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://strwebprdmedia.blob.core.windows.net/media/vxuhotlh/appg-on-osteoporosis-and-bone-health-inq... |
| Description | Radio Interview on BBC (KMG 2024) |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Keith Godfrey was interviewed on BBC Radio News which was broadcast in the early evening and at lunchtime. During his interview he called on councils to do more to support new mothers to stay physically active. He led a study on the activity of 800 women in Southampton and found fewer than half were getting enough moderate to vigorous physical activity. |
| Year(s) Of Engagement Activity | 2023 |
| Description | Royal Osteoporosis Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | speech and presentation |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://theros.org.uk/healthcare-professionals/courses-and-cpd/osteoporosis-conference/ |
| Description | Royal Osteoporosis Society public event 2021 (NCH) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Working group vitamin D ESCEO 21 (NCH) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Southampton experts publish new book |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Press release - Professors Keith Godfrey and Mark Hanson have co-edited a new book published by Cambridge University Press. Developmental Origins of Health and Disease (DOHaD) explores the relationship between early life experiences and adult health. It highlights scientific and clinical advances since a first edition was published in 2006. There have been important breakthroughs in areas such as epigenetics and environmental influences. There is also a new focus on the preconception period and the significance of paternal health. |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.southamptonbrc.nihr.ac.uk/post/southampton-experts-publish-new-book |
| Description | Southampton to lead new national research network |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Press release - Southampton researchers will lead one of several new national UKRI research networks helping tackle challenges in ageing. The MyAge network will focus on pathways of muscle development, differentiation and decline. Over the course of the two-year project, scientists aim to build new directions and collaborations for future research. They will also develop a roadmap of changes that can help people live independently for longer. The 11 new national networks are funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and Medical Research Council (MRC). MyAge is directed in Southampton by Professor Keith Godfrey, Professor Karen Lillycrop and Professor Peter JS Smith. It is also led by Professor Carolyn Greig (Birmingham), Dr Kambiz Alavian (Imperial College), and Dr Mathew Piasecki (Nottingham). |
| Year(s) Of Engagement Activity | 2022 |
| URL | https://www.southamptonbrc.nihr.ac.uk/post/southampton-to-lead-new-national-research-network |
| Description | Speaker at ArLAR Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper was a speaker at the ArLAR Conference. He gave a talk entitled 'Nutritional Approach of Osteoporosis and Fracture Prevention'. This took place on 5th March 2021 |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.arabrheumatology.org |
| Description | Speaker at BRADOO - ABRASSO Congress (Brazilian Association of Bone Assessment and Osteometabolism. |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper gave a talk at this conference entitled 'Closing the treatment gap: An urgent Priority is Osteoporosis Care Worldwide'. This took place on 24th April 2021. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Speaker at Polish Osteoarthrology Society 8th Central European Congress on Osteoporosis and Osteoarthritis. |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attending this congress meeting, and gave a talk entitled 'Management of patients with low, high, and very high risk of osteoporotic fractures'. The meeting was held on 22nd October 2021. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Speaker at WCO-IOF ESCEO Congress (virtual). |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper was a Speaker at this online conference. His talk was entitled 'Management of musculoskeletal disease from cradle to grave.' This took place between 26-27th August 2021, and was attended by over 100 people. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://virtual.wco-iof-esceo.org |
| Description | Speaker at e-ECE2021 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper gave a talk entitled '1 year in Bone'. The event took place on 24th May 2021. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Starter Grants for Clinical Lecturers Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 3rd June 2021. |
| Year(s) Of Engagement Activity | 2021 |
| Description | The 11th ICFSR Conference ASBMR |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this conference on 1st October 2021, and gave a talk entitled 'IOF Capture the Fracture Partnership'. |
| Year(s) Of Engagement Activity | 2021 |
| Description | The American Society for Bone and Mineral Research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation The American Society for Bone and Mineral Research |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.asbmr.org/annual-meeting |
| Description | UKHSA/NHS-England COVID Testing Roadshow |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation "Overview of LAMP technology development and asymptomatic NHS staff testing for COVID-19" |
| Year(s) Of Engagement Activity | 2021 |
| Description | UKRI National Ageing Research network |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Announcement that the University of Southampton will lead one of the eleven new national research networks to tackle challenges in ageing, announced today by the Biotechnology and Biological Sciences Research Council (BBSRC) and Medical Research Council (MRC). Keith Godfrey part of a team of scientists at the University who will lead the MyAge (Muscle resilience across the life course: from cells to society) network. Over the course of the two year project, they aim to build new collaborations and hypotheses for the future of research in this area and develop a roadmap to interventions that can achieve five more years of independent living. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page |
| Description | University of Southampton Science and Engineering Day |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Nick Harvey was part of a team from the MRC LEU that took part in this event. The event was well attended with members of the public showing great interest. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Versus Arthritis RISAPS Supplement Review Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 7th May 2021. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://versusarthritis.org |
| Description | WCO-IOF-ESCEO Conference - Virtual |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Nick Harvey, Deputy Director of MRC LEU gave the Plenary Lecture 2 entitled 'Update of the management of patients at imminent fracture risk at the WCO-IOF-ESCEO conference on 24th March 2022, which was held virtually. This was attended by over 1,000 people. |
| Year(s) Of Engagement Activity | 2022 |
| Description | WHO and Osteoporosis meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended this meeting on 28th June 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | WORLD CONGRESS ON OSTEOPOROSIS, OSTEOARTHRITIS AND MUSCULOSKELETAL DISEASES |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentaiton of IOF Presidents Award |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://www.wco-iof-esceo.org/ |
| Description | Working group on phosphate disorders ES CEO 2021 (NCH) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Working group vitamin D ESCEO 21 (NCH) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Working group vitamin D ESCEO 21 (NCH) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Working group vitamin D ESCEO 21 (NCH) |
| Year(s) Of Engagement Activity | 2021 |