Fully Automatic Segmentation and Assessment of Atrial Scars for Atrial Fibrillation Patients Using LGE MRI

Lead Research Organisation: Imperial College London
Department Name: UNLISTED

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The main objectives of this proposal are to (1) develop a novel data harmonisation method based on recently proposed domain adaptation and generative adversarial models; (2) carry out an initial two-centre cross-national validation study on the retrospectively collected LGE MRI data; (3) independent testing of a multicentre study consists of data collected from four centres, i.e., Brompton (UK), Anam (South Korea), KCL (UK), and Utah (USA), where the data from KCL and Utah are with open access; (4) strengthen further teaching, training and research collaboration links between UK and South Korea clinicians and technicians to gain more understanding about LGE MRI data and deep learning based fibrosis assessment; and (5) enable large-scale basic science and technical development projects and prospective clinical trials at two nations and further international studies.

People

ORCID iD

Publications

10 25 50

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Cui X (2022) MCAL: An Anatomical Knowledge Learning Model for Myocardial Segmentation in 2-D Echocardiography. in IEEE transactions on ultrasonics, ferroelectrics, and frequency control

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Huang J (2022) Swin transformer for fast MRI in Neurocomputing

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Li M (2023) Explainable COVID-19 Infections Identification and Delineation Using Calibrated Pseudo Labels in IEEE Transactions on Emerging Topics in Computational Intelligence

 
Description Cambridge Mathematics of Information in Healthcare Hub 
Organisation Engineering and Physical Sciences Research Council (EPSRC)
Department Centre for Mathematical Imaging in Healthcare
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Developing new collaborations working on MRI denoising models.
Collaborator Contribution Prof Carola-Bibiane Schönlieb and Dr Angelica I. Aviles-Rivero provide guidance and intellectual knowledge input for my PhD student Jiahao Huang via this collaboration. We have regular research meetings and we have joint publications under submission.
Impact Currently, one conference paper is under review and one journal paper is under submission.
Start Year 2022
 
Description Collaboration with Prof Sung Ho Hwang and Dr Yongwon Cho at Korea University Anam Hospital 
Organisation Korea University
Country Korea, Republic of 
Sector Academic/University 
PI Contribution This project supports our collaboration with Prof Sung Ho Hwang and Dr Yongwon Cho at Korea University Anam Hospital to research into multicentre and multinational LGE CMR data.
Collaborator Contribution We have on-going discussions and efforts on building up a multicentre and multinational LGE CMR database.
Impact Publications in preparation.
Start Year 2021
 
Description Prof. Pietro Lio (Cambridge University) on super-resolution for cardiac images 
Organisation University of Cambridge
Department Computer Laboratory
Country United Kingdom 
Sector Academic/University 
PI Contribution We work with Prof. Pietro Lio (Cambridge University) for solving the super-resolution for cardiac images.
Collaborator Contribution Prof. Pietro Lio has expertise in bioinformatics, computational biology models and machine learning, and research studies in integrating various types of data (molecular and clinical, drugs, social and lifestyle) across different spatial and temporal scales of biological complexity to address personalised and precision medicine. Prof. Pietro Lio has contributed his knowledge in our research studies and helped us designed novel super-resolution techniques for cardiac images. He has also provided us guidance and support for our further funding applications.
Impact This collaboration is multi-disciplinary. Prof Pietro Lio has got expertise in medical image analysis. Zhu, Jin, Chuan Tan, Junwei Yang, Guang Yang, and Pietro Lio'. "Arbitrary scale super-resolution for medical images." International Journal of Neural Systems 31, no. 10 (2021): 2150037. Jin Zhu, Guang Yang, Tom Wong, Raad Mohiaddin, David Firmin, Jennifer Keegan, and Pietro Lio. A Single-Image Super-Resolution Method for Late Gadolinium Enhance- ment CMR. In the International Society for Magnetic Resonance in Medicine 27th Annual Meeting (ISMRM) 2019 Jin Zhu, Guang Yang, Pedro Ferreira, Andrew Scott, Sonia Nielles-Vallespin, Jennifer Keegan, Dudley Pennell, Pietro Lio, and David Firmin. A ROI Focused Multi-Scale Super- Resolution Method for the Di usion Tensor Cardiac Magnetic Resonance. In the International Society for Magnetic Resonance in Medicine 27th Annual Meeting (ISMRM) 2019
Start Year 2018