Biomineral Research: Minerals in human health, disease and therapeutics (BMR)

Lead Research Organisation: MRC Human Nutrition Research Group

Abstract

Our research focuses on dietary minerals and on how our bodies handle these small structures to help provide better solutions to unmet needs in nutrition and health. Much of our work concentrates on the digestive system and in understanding how our intestinal cells take up these minerals and with what purpose. Our work integrates different disciplines, such as chemistry, cell biology, human nutrition and immunology, and we collaborate with many different scientists around the world. We then apply some of the lessons learned to other key medical research areas, such as the development of a novel, mineral-based anti-cancer agent. We are very committed to translating our findings for nutritional or therapeutic applications that will improve health.
In summary, our research aims to better describe the fate of dietary mineral particles in our body, their function and what happens when the mechanisms we have to deal with these particles do not work properly. Knowledge gained from our work will contribute to our understanding of the causes of gut inflammatory disorders, such as Crohn’s disease, and perhaps can be used to develop novel therapies, such as for cancer.

Technical Summary

The work of the Biomineral Research Group focuses on minerals, particularly nanomineral synthesis, analysis and cellular handling, to help provide solutions to unmet needs in nutrition and health. Much of our work concentrates on the gastrointestinal tract and in understanding gut handling of mineral nanoparticles: an area of increasingly high priority both nationally and internationally. Our work integrates basic chemical and cellular studies with ex vivo studies (i.e. tissue analysis) and in vivo human studies and, therefore, progresses in a strong translational framework from discovery science through to health applications. We continue to exploit intellectual property that arises through these studies, working closely with MRC Technology.
Our programme aims to (i) better describe why there are endogenous nanomineral pathways in the gastrointestinal tract and how these facilitate cell sampling of luminal macromolecules (ii) demonstrate to what extent engineered nanoparticles, to which we are increasingly exposed, hijack these pathways and are systemically absorbed in humans (iii) delineate whether dysfunction in the cellular handling of endogenous or exogenous nanomineral underlies the cause of Crohn’s disease and (iv) show whether engineered nanoparticles can be exploited as novel immunotherapies to fight cancer.
Our work may provide an important link in understanding how antigen and bacterial components are transported to immune cells of the gut, and how they might work together to ensure safe (tolerant) handling of foreign antigen in this environment. It is also informing on gut handling of nanoparticles and may have implications for the pathogenesis of Crohn’s disease.

Organisations

Publications

10 25 50
publication icon
Aarts M (2013) Tumour selective targeting of cell cycle kinases for cancer treatment. in Current opinion in pharmacology

publication icon
Amirabdollahian F (2009) Is the zinc intake of young people in the UK adequate? in European journal of clinical nutrition

publication icon
Aslam MF (2014) Ferroportin mediates the intestinal absorption of iron from a nanoparticulate ferritin core mimetic in mice. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology

publication icon
Bellmann S (2015) Mammalian gastrointestinal tract parameters modulating the integrity, surface properties, and absorption of food-relevant nanomaterials. in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

 
Description Consultation for the SACN Folate and Disease Prevention Draft Report
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description DEFRA Consultation on Bread and Flour Regulations
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description EFSA public consultation on the 'DRAFT guidance for risk assessment of nanomaterials
Geographic Reach Asia 
Policy Influence Type Participation in a national consultation
Impact Based on the outcome of the public consultation EFSA produced a guideline document for the safety assessment of nanomaterials in foods.
 
Description FAO/WHO Nanofoods (DP) 2012
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
 
Description House of Lords Science and Technology consultation on nanotechnologies and food.
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
 
Description ILSI Europe Workshop on the safety assessment of nanomaterials in food
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
Impact New guidelines currently being drafted.
 
Description Membership of Task Group - Nanorelease ILSI (DP) 2012
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact Review manuscript under peer-review.
 
Description Safety of Nanotechnology in Foods consultation FERA (DP)
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description Action Medical Research Project Grant
Amount £83,234 (GBP)
Organisation Action Medical Research 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2010 
End 12/2011
 
Description Biochemical Society Travel Award
Amount £300 (GBP)
Organisation Biochemical Society 
Sector Learned Society
Country United Kingdom
Start 06/2014 
End 07/2014
 
Description Cambridge International Scholarship (Cambridge Overseas Trust)
Amount £173,100 (GBP)
Organisation University of Cambridge 
Sector Academic/University
Country United Kingdom
Start 10/2011 
End 09/2014
 
Description Case PhD Studentship - HS Pharma
Amount £145,107 (GBP)
Organisation HS Pharma 
Sector Private
Country United States
Start 10/2013 
End 09/2016
 
Description Centenary Award
Amount £24,796 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 09/2012 
End 09/2013
 
Description Conference bursary
Amount £128 (GBP)
Organisation Wellcome Trust 
Department Wellcome Trust Scientific Conferences
Sector Charity/Non Profit
Country United Kingdom
Start 04/2014 
End 05/2014
 
Description DGA Fellowship
Amount € 48,781 (EUR)
Organisation General Directorate for Armament 
Sector Public
Country France
Start 10/2012 
End 09/2013
 
Description Development Gap Fund
Amount £60,350 (GBP)
Funding ID A853/0174 
Organisation MRC-Technology 
Sector Academic/University
Country United Kingdom
Start 06/2014 
End 01/2015
 
Description Development Gap Fund
Amount £43,973 (GBP)
Funding ID A853-0185 
Organisation MRC-Technology 
Sector Academic/University
Country United Kingdom
Start 01/2017 
End 06/2017
 
Description Development Gap Fund
Amount £202,000 (GBP)
Funding ID A853/0176 
Organisation MRC-Technology 
Sector Academic/University
Country United Kingdom
Start 09/2016 
End 09/2018
 
Description Emerging Technologies Competition 2014
Amount £10,000 (GBP)
Funding ID Life Sciences Winner 2014 
Organisation Royal Society of Chemistry 
Sector Learned Society
Country United Kingdom
Start 06/2014 
 
Description IBD Research Grant
Amount £64,545 (GBP)
Organisation Institute Of Brewing and Distilling 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2010 
End 09/2011
 
Description IBD Research Grant and PhD studentships
Amount £532,000 (GBP)
Organisation Institute Of Brewing and Distilling 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2007 
End 09/2010
 
Description MRCT Development Gap Funding
Amount £36,726 (GBP)
Funding ID A853/0181 
Organisation MRC-Technology 
Sector Academic/University
Country United Kingdom
Start 10/2015 
End 03/2016
 
Description MRCT Development Gap Funding
Amount £770,000 (GBP)
Funding ID A853-0040 
Organisation MRC-Technology 
Sector Academic/University
Country United Kingdom
Start 02/2005 
End 08/2009
 
Description Malaysian Government Scholarship (King's Scholarship)
Amount £147,414 (GBP)
Funding ID JPA(I)910116035591 
Organisation Malaysian High Commission 
Sector Public
Country United Kingdom
Start 01/2017 
End 12/2020
 
Description Post-graduate studentship in human nutrition
Amount £30,000 (GBP)
Organisation Rank Prize Funds 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2008 
End 09/2011
 
Description Research Bursary
Amount £1,500 (GBP)
Organisation University of Cambridge 
Department Cambridge Society for the Application of Research (CSAR)
Sector Charity/Non Profit
Country United Kingdom
Start 05/2014 
End 12/2014
 
Description Research Contract CC
Amount £58,249 (GBP)
Organisation The Coca-Cola Company 
Sector Private
Country United States
Start 12/2011 
End 06/2012
 
Description Research Contract Lonza
Amount £90,000 (GBP)
Organisation Lonza Group 
Sector Private
Country Global
Start 05/2012 
End 05/2013
 
Description Research Grant DC
Amount £150,000 (GBP)
Organisation Dairy Council 
Sector Private
Country United Kingdom
Start 04/2007 
End 04/2010
 
Description Research contract PTL
Amount £360,000 (GBP)
Organisation Shield Therapeutics 
Sector Private
Country United Kingdom
Start 07/2012 
End 05/2015
 
Description Travel Grant/Biochemical Society
Amount £400 (GBP)
Organisation Biochemical Society 
Sector Learned Society
Country United Kingdom
Start 12/2009 
End 11/2010
 
Description Travel and registration award
Amount £360 (GBP)
Organisation University of Cambridge 
Department Gonville and Caius College
Sector Academic/University
Country United Kingdom
Start 04/2014 
End 05/2014
 
Description Travel award
Amount £150 (GBP)
Organisation University of Cambridge 
Sector Academic/University
Country United Kingdom
Start 06/2014 
End 07/2014
 
Title Nano iron (IHAT/IMH) 
Description Nanoparticulate Fe(III) oxo-hydroxide to use as a mimetic of digested dietary iron in in vitro and in vivo studies investigating the mechanisms of absorption of dietary iron. 
Type Of Material Model of mechanisms or symptoms - in vitro 
Year Produced 2011 
Provided To Others? Yes  
Impact Composition of mater patent: WO/2008/096130 Several papers in preparation. Established collaborations. 
 
Description Aluminium detoxification and the role of silicon in a multicellular organism 
Organisation University of Manchester
Country United Kingdom 
Sector Academic/University 
PI Contribution Intellectual contribution to study design and analysis/interpretation of results. Expert knowledge on the chemistry of silicon and aluminium and expertise and facility for the total analysis of silicon and aluminium by ICPOES.
Collaborator Contribution A model to investigate the biological role and essentiality of silicon. Expertise in freshwater invertebrates.
Impact Publications, 18409657, 16242225
 
Description Analysis of isotopic ratios 
Organisation Imperial College London
Department Department of Earth Science & Engineering
Country United Kingdom 
Sector Academic/University 
PI Contribution led collaborative work where a novel method (DRC-ICP-MS) was developed to determine stable isotope enrichment (58Fe) in nutritional/clinical studies. We confirmed the accuracy of the novel methodology by MC-ICP-MS (Imperial college)
Collaborator Contribution MC-ICP-MS analyses
Impact Publication: Journal of Analytical Atomic Spectrometry (2011) 26, 8, 1648-1652
Start Year 2007
 
Description Biological effects of silicon in relation to wound healing and tissue repair 
Organisation Pierre and Marie Curie University - Paris 6
Department Laboratory of Condensed Matter and Physical Chemistry
Country France 
Sector Academic/University 
PI Contribution Input in to silicon analysis, silicon biochemistry and cell biology.
Collaborator Contribution Expertise in silica nanoparticles synthesis and their metabolism and their interaction with collagen.
Impact This has resulted in personal funding being awarded to a post-doc from UPMC to visit the UK and carryout collaborative research in our labs for 12 month.
Start Year 2012
 
Description Bone related studies in small animal models 
Organisation Addenbrooke's Hospital
Department Orthopaedic Research Unit Addenbrooke's
Country United Kingdom 
Sector Hospitals 
PI Contribution Intellectual lead. Concept and design of studies. Expertise in silicon analysis and on dietary silicon.
Collaborator Contribution Expert knowledge on bone and bone analyses including small animals and small animal models.
Impact Publication 18550464
Start Year 2006
 
Description Cobalt and Chromium levels in blood plasma from hip Artheroplasty patients 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution We provided expertise in analysis of trace levels of cobalt and chromium in biological samples and how to measure immunological responses in T cells after exposure to trace metals.
Collaborator Contribution Contributed to our portofolio of trace element analysis.
Impact Publications 18924077, 19483243, 22688088, 24990974
Start Year 2007
 
Description Development of low silicon rodent diets 
Organisation U.S. Department of Agriculture USDA
Department Grand Forks Human Nutrition Research Center
Country United States 
Sector Academic/University 
PI Contribution Intellectual lead. Concept and design of studies. Expertise in silicon analysis and on dietary silicon.
Collaborator Contribution Expertise in the development and preparation of low silicon/silicon-deprived diets and in conducting silicon deprivation and supplementation studies in small animals. Expert on silicon biology.
Impact Publication 18550464
 
Description Dietary microparticles and intestinal health 
Organisation AgResearch
Country New Zealand 
Sector Public 
PI Contribution Intellectual contributions. Provide expertise knowledge on dietary titanium dioxide, intestinal health and IBD.
Collaborator Contribution Animal model expertiseAnimal model expertise
Impact Publication: Dietary Exposure to Titanium Dioxide Does Not Affect Growth and Immune Cell Composition of Peyer's Patches and Mesenteric Lymph Nodes in Healthy Mice Riedle S, Thomas-McKay E, Otter DE, Pele L, Powell JJ, Singh H, Roy NC. Source: METAL IONS IN BIOLOGY AND MEDICINE, VOL 11 Book Series: METAL IONS IN BIOLOGY AND MEDICINE Volume: 11 Pages: 225-230 Published: 2011
Start Year 2010
 
Description Dietary microparticles and intestinal health 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Intellectual lead. Provided knowledge and expertise on nano- and micro-particulate minerals of the gut.
Collaborator Contribution Gastroenterology expertise
Impact Publications 18787776 17951488 17522811
 
Description Dietary microparticles and intestinal health 
Organisation Massey University
Department Riddet Institute
Country New Zealand 
Sector Academic/University 
PI Contribution Intellectual contributions. Provide expertise knowledge on dietary titanium dioxide, intestinal health and IBD.
Collaborator Contribution Animal model expertiseAnimal model expertise
Impact Publication: Dietary Exposure to Titanium Dioxide Does Not Affect Growth and Immune Cell Composition of Peyer's Patches and Mesenteric Lymph Nodes in Healthy Mice Riedle S, Thomas-McKay E, Otter DE, Pele L, Powell JJ, Singh H, Roy NC. Source: METAL IONS IN BIOLOGY AND MEDICINE, VOL 11 Book Series: METAL IONS IN BIOLOGY AND MEDICINE Volume: 11 Pages: 225-230 Published: 2011
Start Year 2010
 
Description Dietary microparticles and intestinal health 
Organisation University of Cambridge
Department Department of Physiology, Development and Neuroscience
Country United Kingdom 
Sector Academic/University 
PI Contribution Intellectual lead. Provided knowledge and expertise on nano- and micro- particulate minerals of the gut.
Collaborator Contribution Provided technical guidance and expertise on microscopy (Confocal, STEM and SEM).
Impact Publication 18787776
 
Description Dietary microparticles and intestinal health 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution Intellectual lead. Provide knowledge and expertise on nano- and micro-particulate minerals of the gut.
Collaborator Contribution Human and animal Gastroenterology expertise.
Impact Publication 22397822
Start Year 2006
 
Description Dietary microparticles and intestinal health 
Organisation University of Edinburgh
Department The Roslin Institute
Country United Kingdom 
Sector Academic/University 
PI Contribution Intellectual lead. Provide knowledge and expertise on nano- and micro-particulate minerals of the gut.
Collaborator Contribution Animal Expertise
Impact Publication submitted
Start Year 2014
 
Description Dietary silicon depletion studies 
Organisation U.S. Department of Agriculture USDA
Department Grand Forks Human Nutrition Research Center
Country United States 
Sector Academic/University 
PI Contribution Knowledge on silicon chemistry and biochemistry.
Collaborator Contribution Provided silicon depleted and silicon replete diets for small in vivo studies. Experience with dietary intervention studies in small animals.
Impact Publication: 18550464
 
Description Dietray silicon metabolism and health 
Organisation Loei Rajabhat University
Department Faculty of Science and Technology
Country Thailand 
Sector Academic/University 
PI Contribution Knowledge and expertise on the chemistry and biochemistry of silicon and facilities for total silicon analysis.
Collaborator Contribution Expertise on dietary silicon metabolism, experience in conducting volunteer-based supplementation/intervention studies.
Impact Publications: 23702224, 23433536, 19356271, 19257829, 15005826,
 
Description Effect of polysilicates on T cell function 
Organisation University of Cambridge
Department Department of Pathology
Country United Kingdom 
Sector Academic/University 
PI Contribution Undertaken the studies, intellectual input into study design and data analysis
Collaborator Contribution Intellectual input into study design and data analysis, provision of material (tissues, cell lines) for the study
Impact Data for publication.
Start Year 2015
 
Description Effect of silicon and alcohol on bone health 
Organisation University of Aberdeen
Country United Kingdom 
Sector Academic/University 
PI Contribution Provided dietary silicon intake values and knowledge on silicon biochemistry.
Collaborator Contribution Epidemiological and statistical analysis and access to APOSS cohort dataset.
Impact Publications: 22456655, 22173054
 
Description Elemental analysis 
Organisation University of Cambridge
Department Department of Materials Science & Metallurgy
Country United Kingdom 
Sector Academic/University 
PI Contribution Provided elemental analysis of biomaterials
Collaborator Contribution The publications arising from this work contribute to our recognision in the trace elemental analysis field
Impact One published paper and several in preparation.
Start Year 2007
 
Description Epidemiological studies on dietary silicon intake, alcohol intake and bone health 
Organisation Boston University
Country United States 
Sector Academic/University 
PI Contribution Intellectual lead. Provided the initial study ideas and designs for this collaboration. Expert knowledge on silicon.
Collaborator Contribution Statistical expertise and advice in relation to population-based epidemilogical studies.
Impact Publication 19244365 Publication 14969400
 
Description Epidemiological studies on dietary silicon intake, alcohol intake and bone health 
Organisation Harvard University
Department Harvard Medical School
Country United States 
Sector Academic/University 
PI Contribution Intellectual lead. Provided the initial ideas and designs for the collaborative studies and expert knowledge on dietary silicon.
Collaborator Contribution Provided access to the Framingham population-based cohorts for the studies on dietary silicon intake and alcohol intake and bone health. Provided intellectual input and consultation throughout these studies.
Impact Publication 19244365 Publication 14969400 Publication 11976163
 
Description Epidemiological studies on dietary silicon intake, alcohol intake and bone health 
Organisation Tufts University
Country United States 
Sector Academic/University 
PI Contribution Intellectual lead. Provided the initial study ideas and design for the collaborative studies. Expert knowledge on dietary silicon, silicon content of foods and its bioavailability and access to the dietary silicon food database.
Collaborator Contribution Provided expertise on population-based epidemiological analyses and carried out the analyses between silicon and alcohol intakes and bone health.
Impact Publication 19244365 Publication 14969400 Publication 11976163
 
Description Health economics of oral iron 
Organisation Bangor University
Department Centre for Health Economics and Medicines Evaluation
Country United Kingdom 
Sector Academic/University 
PI Contribution This project concerns the use of data from the Clinical Practice Research Datalink (CPRD) and secondary care records corresponding to approximately 422k patients prescribed oral iron to 1. Model prescription rates with oral iron in the UK; 2. Model patterns of response to treatment with oral iron and 3. Health economics model of the use of ferrous iron salts in primary care in the UK. Our group leads this project, including securing funding and applying (ISAC) for data extraction through the collaboration with the University of Cambridge. The data analysis concerning 1. and 2. above will be carried out at MRC HNR. Publications from this work will be driven by our group.
Collaborator Contribution The University of Oxford will provide clinical/GP input during all stages of the project . Bangor University will carry out the health economics model (point 3. above). Bangor has extensive experience with economic analyses for NICE and one of the leading health economics centers in the UK. The University of Cambridge holds a gold license to CPRD for use of data extracted from this database. The University of Cambridge will contribute with data extraction and know-how on the coding system within the database to allow interpretation/analysis of the data.
Impact Secured funding from MRCT Development Gap Fund. Multi-disciplinary: Public Health Primary Care Health Economics Statistics
Start Year 2014
 
Description Health economics of oral iron 
Organisation University of Cambridge
Department MRC Biostatistics Unit
Country United Kingdom 
Sector Public 
PI Contribution This project concerns the use of data from the Clinical Practice Research Datalink (CPRD) and secondary care records corresponding to approximately 422k patients prescribed oral iron to 1. Model prescription rates with oral iron in the UK; 2. Model patterns of response to treatment with oral iron and 3. Health economics model of the use of ferrous iron salts in primary care in the UK. Our group leads this project, including securing funding and applying (ISAC) for data extraction through the collaboration with the University of Cambridge. The data analysis concerning 1. and 2. above will be carried out at MRC HNR. Publications from this work will be driven by our group.
Collaborator Contribution The University of Oxford will provide clinical/GP input during all stages of the project . Bangor University will carry out the health economics model (point 3. above). Bangor has extensive experience with economic analyses for NICE and one of the leading health economics centers in the UK. The University of Cambridge holds a gold license to CPRD for use of data extracted from this database. The University of Cambridge will contribute with data extraction and know-how on the coding system within the database to allow interpretation/analysis of the data.
Impact Secured funding from MRCT Development Gap Fund. Multi-disciplinary: Public Health Primary Care Health Economics Statistics
Start Year 2014
 
Description Health economics of oral iron 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution This project concerns the use of data from the Clinical Practice Research Datalink (CPRD) and secondary care records corresponding to approximately 422k patients prescribed oral iron to 1. Model prescription rates with oral iron in the UK; 2. Model patterns of response to treatment with oral iron and 3. Health economics model of the use of ferrous iron salts in primary care in the UK. Our group leads this project, including securing funding and applying (ISAC) for data extraction through the collaboration with the University of Cambridge. The data analysis concerning 1. and 2. above will be carried out at MRC HNR. Publications from this work will be driven by our group.
Collaborator Contribution The University of Oxford will provide clinical/GP input during all stages of the project . Bangor University will carry out the health economics model (point 3. above). Bangor has extensive experience with economic analyses for NICE and one of the leading health economics centers in the UK. The University of Cambridge holds a gold license to CPRD for use of data extracted from this database. The University of Cambridge will contribute with data extraction and know-how on the coding system within the database to allow interpretation/analysis of the data.
Impact Secured funding from MRCT Development Gap Fund. Multi-disciplinary: Public Health Primary Care Health Economics Statistics
Start Year 2014
 
Description Health economics of oral iron 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution This project concerns the use of data from the Clinical Practice Research Datalink (CPRD) and secondary care records corresponding to approximately 422k patients prescribed oral iron to 1. Model prescription rates with oral iron in the UK; 2. Model patterns of response to treatment with oral iron and 3. Health economics model of the use of ferrous iron salts in primary care in the UK. Our group leads this project, including securing funding and applying (ISAC) for data extraction through the collaboration with the University of Cambridge. The data analysis concerning 1. and 2. above will be carried out at MRC HNR. Publications from this work will be driven by our group.
Collaborator Contribution The University of Oxford will provide clinical/GP input during all stages of the project . Bangor University will carry out the health economics model (point 3. above). Bangor has extensive experience with economic analyses for NICE and one of the leading health economics centers in the UK. The University of Cambridge holds a gold license to CPRD for use of data extracted from this database. The University of Cambridge will contribute with data extraction and know-how on the coding system within the database to allow interpretation/analysis of the data.
Impact Secured funding from MRCT Development Gap Fund. Multi-disciplinary: Public Health Primary Care Health Economics Statistics
Start Year 2014
 
Description Identifying the biological role of silicon. 
Organisation Lakehead University
Country Canada 
Sector Academic/University 
PI Contribution Expertise and facility for silicon analysis by ICP-OES and for cell culture and molecular biology studies. Experience and knowledge in conducting small ingestion/absorption studies, particularly for silicon.
Collaborator Contribution Expert knowledge on silicon chemistry and analysis by NMR. Constant provider of ideas, advice and consultation.
Impact Silicon Conferences Publication 23622499 Publication: book chapter
 
Description Intracellular processing of calcium phosphate nanoparticles in human health and in Crohn's Disease 
Organisation Open University
Country United Kingdom 
Sector Academic/University 
PI Contribution Financial contribution to a PhD studentship. Co-supervision of the PhD student. Access to research facility and expertise in calcium phosphate nanoparticles and Crohn's Disease.
Collaborator Contribution Experience and expertise in charactering intracellular calcium handling. Co-supervision of PhD student.
Impact None as yet.
Start Year 2017
 
Description Investigations assessing intestinal antigen transport in health and disease 
Organisation Linkoping University
Department Department of Clinical and Experimental Medicine
Country Sweden 
Sector Academic/University 
PI Contribution The research team will provide expertise for the processing, immunohistochemical staining and analyses of intestinal tissues and be responsible for the critical interpretation of the generated data.
Collaborator Contribution Linköping University is responsible for the sourcing, phenotyping, genotyping, coding and shipping of the study samples. Ussing chamber experiments will also draw on the experience and expertise of Linköping University. Linköping will be responsible for the critical interpretation of the generated data.
Impact No outputs as yet.
Start Year 2017
 
Description Measurement of selenium in blood plasma and incidence of prostate cancer 
Organisation Cancer Research UK
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Using our expertise and specialised laboratory for trace element analysis in biological samples, we analysed selenium levels in 2000 blood plasma samples from a European cohort looking at the incidence of prostate cancer.
Collaborator Contribution Contributed to our portofolio of trace elements analysis
Impact Method
 
Description Mechanistic studies on dietary silicon 
Organisation University of Antwerp
Country Belgium 
Sector Academic/University 
PI Contribution Intellectual lead. Concept and design of studies. Expertise on the analysis of silicon, in conducting cell culture studies and experience in conducting small ingestion/absorption studies.
Collaborator Contribution Funding (pre 2006). Expert knowledge on silicon absorption and speciation. Experience in conducting small animal studies to investigate the effect of dietary silicon on bone. Expertise in bone analyses (micro-CT).
Impact Publications, 18547426, 18550464
 
Description Mercury-selenium interactions in NDNS participants 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution We lead on the dietary intake work and initiated the hypothesis
Collaborator Contribution Two papers published
Impact Publication
 
Description Novel Oral Iron Preparations 
Organisation ETH Zurich
Department Institute of Food, Nutrition and Health
Country Switzerland 
Sector Public 
PI Contribution To provide novel iron materials to test in specialised animal models to investigate pathways of uptake
Collaborator Contribution To provide specialised animal models
Impact Study currently under way. No outputs yet.
Start Year 2013
 
Description Novel Oral Iron Preparations 
Organisation King's College London
Department School of Medicine KCL
Country United Kingdom 
Sector Academic/University 
PI Contribution Intellectual leadership. Synthesis and formulation of the nanoparticulate iron materials tested.
Collaborator Contribution Conducted rodent studies to test the novel iron compounds for absorption and pathway of intestinal uptake. Manuscripts currently under preparation.
Impact Multi-disciplinary collaboration: cell biology, animal studies, chemistry, nanotechnology. Publications: 24899360, 24394211, 25342699
Start Year 2011
 
Description Novel Oral Iron Preparations 
Organisation University of California, Berkeley
Department Department of Nutritional Science and Toxicology
Country United States 
Sector Academic/University 
PI Contribution Intellectual leadership. Synthesis and formulation of the nanoparticulate iron materials tested.
Collaborator Contribution Provided expertise in the safety assessment of the novel iron compounds.
Impact Proved that lead compound was safe to gut cells using cellular models. Multi-disciplinary collaboration: cell biology, chemistry, nanotechnology. Publication 24983890
Start Year 2011
 
Description Novel Oral Iron Preparations 
Organisation University of Hasselt
Department Institute for Materials Research
Country Belgium 
Sector Academic/University 
PI Contribution Intellectual leadership. Synthesis and formulation of the materials tested.
Collaborator Contribution Provided expertise in electron microscopy analysis of iron oxide materials.
Impact Publication 19116170 Data for patent : GB2008000408
 
Description Novel Oral Iron Preparations 
Organisation University of Queensland
Department Queensland Institute of Medical Research
Country Australia 
Sector Academic/University 
PI Contribution Intellectual leadership. Animal studies for mechanistic assessment of novel nanoparticulate iron formulations.
Collaborator Contribution Provided expertise and animal models of different pathways in iron homeostasis
Impact Hosting PhD student to carry out specialised animal studies. Publications: 24983890, 24776745 Pereira, D. I. A.; Aslam, M. F.; Frazer, D. M.; Schmidt, A.; Walton, G. E.; McCartney, A. L.; Gibson, G. R.; Anderson, G. J.; Powell, J. J., Dietary iron depletion at weaning imprints low gut microbiome diversity and this is not recovered with oral nano Fe(III). . MicrobiologyOpen In Press.
Start Year 2011
 
Description Polysilicate and experimental metastasis 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution Study design, preparation and provision of polysilicate preparations, tissue analysis and data analysis.
Collaborator Contribution Study design, in vivo testing of polysilicate preparations, sample and data analysis.
Impact Significant amount of data for publication(s).
Start Year 2015
 
Description Silicon depletion study 
Organisation University of Hasselt
Country Belgium 
Sector Academic/University 
PI Contribution Intellectual lead. Concept and design of study. Expertise in silicon analysis and on dietary silicon.
Collaborator Contribution Expertise in bone analyses in small animals; DEXA and mechanical testing.
Impact Publication 18550464
 
Description Silicon supplementation trial in osteopenic women 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Intellectual lead. Initial design of the clinical trial protocol and input in the final design of clinical trial and analysis/interpretation of the data. Provided expert knowledge on dietary silicon and health and on silicon analysis.
Collaborator Contribution Expertise and knowledge on bone and markers of bone health and in conducting clinical studies to investigate effects on bone health. Access to facilities to undertake clinical studies/trial on bone health.
Impact Publication 18547426
 
Description Targeting the nanomineral-antigen-peptidoglycan pathway to reverse Crohn's Disease 
Organisation University College London
Department School of Pharmacy
Country United Kingdom 
Sector Academic/University 
PI Contribution Lead on the MRCT DGF project 'Targeting the nanomineral-antigen-peptidoglycan pathway to reverse Crohn's Disease'.
Collaborator Contribution Dr Abdul Basit is bringing expertise for the microsome/mini-capsule formulation work necessary for some aspects of the DGF.
Impact N/A yet
Start Year 2015
 
Description Targeting the nanomineral-antigen-peptidoglycan pathway to reverse Crohn's Disease 
Organisation University of Toronto
Country Canada 
Sector Academic/University 
PI Contribution Lead on the DGF 'Targeting the nanomineral-antigen-peptidoglycan pathway to reverse Crohn's Disease'.
Collaborator Contribution University of Toronto will, on a fee-for-service basis, undertake the Nod1/2 double knockout mouse studies and provide samples for PD-L1 analysis.
Impact N/A yet
Start Year 2014
 
Description The analysis of titanium in whole blood - an inter-laboratory comparison to determine the best practise 
Organisation Charing Cross Hospital
Country United Kingdom 
Sector Hospitals 
PI Contribution Provided the blood samples for the inter-laboratory comparison of titanium levels in whole blood.
Collaborator Contribution Provided results of their analysis of titanium in the whole blood samples.
Impact A peer-reviewed paper.
Start Year 2016
 
Description The analysis of titanium in whole blood - an inter-laboratory comparison to determine the best practise 
Organisation Health and Safety Laboratory
Department Biological Monitoring
Country United Kingdom 
Sector Private 
PI Contribution Provided the blood samples for the inter-laboratory comparison of titanium levels in whole blood.
Collaborator Contribution Provided results of their analysis of titanium in the whole blood samples.
Impact A peer-reviewed paper.
Start Year 2016
 
Description The analysis of titanium in whole blood - an inter-laboratory comparison to determine the best practise 
Organisation Laboratory of the Government Chemist (LGC) Ltd
Country United Kingdom 
Sector Private 
PI Contribution Provided the blood samples for the inter-laboratory comparison of titanium levels in whole blood.
Collaborator Contribution Provided results of their analysis of titanium in the whole blood samples.
Impact A peer-reviewed paper.
Start Year 2016
 
Description The analysis of titanium in whole blood - an inter-laboratory comparison to determine the best practise 
Organisation National Institute of Scientific Research (INRS)
Country Canada 
Sector Academic/University 
PI Contribution Provided the blood samples for the inter-laboratory comparison of titanium levels in whole blood.
Collaborator Contribution Provided results of their analysis of titanium in the whole blood samples.
Impact A peer-reviewed paper.
Start Year 2016
 
Description The analysis of titanium in whole blood - an inter-laboratory comparison to determine the best practise 
Organisation SAS Trace Element Centre
Country United Kingdom 
Sector Private 
PI Contribution Provided the blood samples for the inter-laboratory comparison of titanium levels in whole blood.
Collaborator Contribution Provided results of their analysis of titanium in the whole blood samples.
Impact A peer-reviewed paper.
Start Year 2016
 
Description The analysis of titanium in whole blood - an inter-laboratory comparison to determine the best practise 
Organisation University of Wales
Department Centre for Advanced Welsh and Celtic Studies
Country United Kingdom 
Sector Academic/University 
PI Contribution Provided the blood samples for the inter-laboratory comparison of titanium levels in whole blood.
Collaborator Contribution Provided results of their analysis of titanium in the whole blood samples.
Impact A peer-reviewed paper.
Start Year 2016
 
Description Vitamin B6 and cognition 
Organisation University of Maine
Country United States 
Sector Academic/University 
PI Contribution Analysis
Collaborator Contribution They were PIs.
Impact Publication
 
Title Amorphous Magnesium-Substituted Calcium Phosphate Compositions and Their Uses 
Description Amorphous Magnesium-Substituted Calcium Phosphate which are presently being developed to treat IBD conditions. PCT filing in 2014 published in 2015. 
IP Reference WO2015067939 
Protection Patent application published
Year Protection Granted 2015
Licensed No
Impact Currently being further developed as part of the group's core research.
 
Title Antibacterial compositions comprising copper oxo-hydroxide nanoparticles and their uses as biocidal agents 
Description The present invention relates to antibacterial compositions comprising copper oxo-hydroxide nanoparticles, and in particular to ligand-modified copper oxo-hydroxide nanoparticles and their uses as antibacterial agents capable of delivering soluble biocidal copper. The present invention further relates to medical uses of the ligand-modified copper oxo-hydroxide 
IP Reference WO2016170152 
Protection Patent application published
Year Protection Granted 2016
Licensed No
Impact Currently being further developed as part of a PhD project.
 
Title Compositions comprising nanosilica particles and their use in methods of activating T lymphocytes for therapy 
Description Novel resorbable nano-silicates that can be used to activate T-cells thus providing clinical tool for cancers or inflammatory diseases. 
IP Reference WO2018029247 
Protection Patent application published
Year Protection Granted 2018
Licensed Yes
Impact These non-persistent moieties, which are undergoing clinical development by the licensee, could be become a safe and affordable strategy to deal with a range of cancers.
 
Title Ligand modified poly oxo-hydroxy metal ions materials, their uses and processes for their preparation 
Description The invention relates to ligand-modified poly oxo-hydroxy metal ion materials and their uses, in particular for nutritional, medical, cosmetic or biologically related applications;for example, for the treatment of a deficiency related to a component of the material (e.g. iron supplement). The invention further relates to processes for preparing the materials and optimising their physico-chemical properties and their medical uses. 
IP Reference WO2008096130 
Protection Patent granted
Year Protection Granted 2009
Licensed Yes
Impact (1) the discovery has informed upon an entirely novel pathway for dietary iron absorption (published and more publications to come). (2) the discovery has allowed applications of similar chemistry to generate other novel nanomineral materials with potential nutritional and therapeutic applications - IP for these is in various stages of protection and licencing discussions.
 
Title Materials and methods relating to stabilised polymeric silicate compositions 
Description Stabilised silicates to treat a variety of clinical conditions. PCT filing in 2015 
IP Reference WO2015121666 
Protection Patent application published
Year Protection Granted 2015
Licensed Yes
Impact Resulted in the industrial funding of a PHD studentship and an ongoing programme of research
 
Title Methods for producing carboxylate ligand modified ferric iron hydroxide colloids and related compositions and uses 
Description Processes for recovering colloids of carboxylate ligand modified ferric iron hydroxide materials such as IHAT (Iron Hydroxide Adipate Tartrate) are described based on the use of water miscible non-aqueous solvents, such as ethanol, methanol and acetone. The processes produce materials with advantageous properties such as improved bioavailability, reduced aggregation and/or agglomeration and/or increased iron content. 
IP Reference WO2017060441 
Protection Patent application published
Year Protection Granted 2017
Licensed Yes
Impact This novel synthesis enables cheaper and faster recovery of ferritin like mimetics (IHAT) for the treatment of iron deficiency anaemia. It is now currently being employed to produce IHAT at scale by the licensee.
 
Title Methods for producing ferric maltol compositions from elemental iron 
Description Methods for producing ferric maltol compositions, such as ferric trimaltol, from elemental iron, and ferric maltol compositions produced by these methods and their uses are described. 
IP Reference WO2017167969 
Protection Patent application published
Year Protection Granted 2017
Licensed Commercial In Confidence
Impact Novel and cheap method for the synthesis of a bioavailable iron complexes. Has the potential to increase patient affordability.
 
Title Methods for producing ferric maltol compositions from ferrous hydroxides 
Description Methods for producing ferric maltol compositions, such as ferric trimaltol, from ferrous hydroxides, are described, as well as ferric maltol compositions produced by these methods and their uses. 
IP Reference WO2017167970 
Protection Patent application published
Year Protection Granted 2017
Licensed Commercial In Confidence
Impact Novel and cheap method for the synthesis of a bioavailable iron complexes. Has the potential to increase patient affordability.
 
Title Methods for producing ferric maltol compositions from ligand modified and ligand coated ferric hydroxides 
Description Methods for producing ferric maltol compositions, such as ferric trimaltol,are described in which maltol is reacted with a ligand modified ferric hydroxide and/or a ligand coated ferric hydroxide 
IP Reference WO2017167963 
Protection Patent application published
Year Protection Granted 2017
Licensed Commercial In Confidence
Impact Novel and cheap method for the synthesis of a bioavailable iron complexes. Has the potential to increase patient affordability.
 
Title Oxygen sensors and their uses 
Description Novel oxygen sensors based on metal oxo-hydroxides were developed. The sensors are useful in many technical fields, and find particular application in the field of food packaging as they are safely disposable (e.g. are environmentally friendly), cheap to manufacture, and provide detectable changes in the presence of oxygen that are easy to read. 
IP Reference WO2012101407 
Protection Patent application published
Year Protection Granted 2013
Licensed No
Impact The synthetic strategy is very versatile and is being exploited to produce materials for other application, e.g. antimicrobials.
 
Title Phosphate binding materials and their uses 
Description Phosphate binding materials and compositions comprising them which are solid ligand-modified poly oxo-hydroxy metal ion materials are disclosed that are based on ferric iron oxo- hydroxides modified with carboxylic acid ligands, or ionised forms thereof. These materials are made and tested in the examples provided in the application to demonstrate that they can bind phosphate in "in vitro" an in "in vivo" studies. They are useful for treating hyperphosphatenia or for removing phosphate from a medium. 
IP Reference WO2010015827 
Protection Patent granted
Year Protection Granted 2010
Licensed Yes
Impact Novel therapeutic agent (phosphate binder) for renal patients has completed Phase II clinical trials with positive results.
 
Title Stabilised silicate compositions and their use as antiperspirant compositions 
Description Novel aluminium free antiperspirant agents based on amorphous silicate actives 
IP Reference WO2015121667 
Protection Patent application published
Year Protection Granted 2015
Licensed Yes
Impact Currently being developed by a Beiersdorf for personal care applications.
 
Title IHAT Phase II Clinical Trial 
Description Currently undergoing Phase 0 testing, funded by MRC Technology Development Gap Fund. The next stage of the clinical development of the medical product will start in April 2016 with a project for a Phase II clinical trial in children (NCT02941081). This trial will be conducted at the MRC Unit, The Gambia with funding from the Bill and Melinda Gates Foundation, Grand Challenges. This work follows on from nearly 11 years of pre-clinical and proof-of-concept development, which ended in 2015, at MRC HNR. 
Type Therapeutic Intervention - Drug
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2015
Development Status Under active development/distribution
Clinical Trial? Yes
Impact This medical product is has been licensed to Expharma Ltd. 
URL https://clinicaltrials.gov/show/NCT02498886
 
Title Novel Oral Iron Therapeutic 
Description Pre-clinical package includes in vitro and in vivo pharmacokinetics and safety assessment and phase 0 human studies. 
Type Therapeutic Intervention - Drug
Current Stage Of Development Refinement. Non-clinical
Year Development Stage Completed 2015
Development Status Closed
Impact The first patent application entitled "Ligand modified poly oxy-hydroxy metal ion materials, their uses and processes for their preparation" was filed as a UK priority and a US provisional patent application on 6th February 2007 and both applications subsequently proceeded to grant. A PCT application (PCT/GB2008/000408) was filed on 6th February 2008. The PCT patent application entered the national phase on 6th August 2009. All the patent territories and statuses are given in the table below. Territory Number Status Israel 199901 Granted South Korea 10-2009-7016904 Allowed Brazil PI0807212-4 In examination India 2713/KOLNP/2009 In examination Eurasia 019635 Granted South Africa 2009/05083 Granted Europe 08709331.6 Granted Singapore 154173 Granted United States 8058462 Granted Hong Kong 10105191.4 Granted Mexico 288069 Granted China 20088004288.2 Granted Canada 2,676,146 In examination Australia 2008212653 Granted Japan 2009-548736 Granted United Kingdom 2451713 Granted A further patent application entitled "Methods for Producing Carboxylate Ligand Modified Ferric Iron Hydroxide Colloids" claiming a more scalable method of manufacturing IHAT was filed as a UK priority patent application on 9th October 2015. 
 
Title Phosphate binder 
Description Phosphate binder for renal patients that has been licenced (2012). A Phase II clinical trial was completed recently with positive results. 
Type Therapeutic Intervention - Drug
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2011
Development Status Under active development/distribution
Impact This product has the potential to be the most effective phosphate binder to date. 
URL https://clinicaltrials.gov/ct2/show/NCT02151643?term=PT20&rank=1
 
Company Name Phosphate Therapeutics Ltd (PTL) 
Description MRC is a stake holder in PTL and the role of the company is to develop a licenced MRC therapeutic namely PT20, an oral phosphate binder for renal patients, through phase II and III clinical trials with the view to bringing therapeutic to market for significantly improved patient benefit. 
Year Established 2012 
Impact funding achieved and FDA approved in principal for a phase II clinical trial.
 
Description 34th International Medical Advisory Group- Copenhagen- 2006 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Talk at the 34th International Medical Advisory Group Conference in Copenhagen, Denmark on 'The place of beer in nutrition.' The talk stimulated industry on benefits that beer might yeild.

Industry will look at this further.
Year(s) Of Engagement Activity 2006
 
Description 4th European Beer and Health Symposium- Silicon and bone- 2006 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Talk at the 4th European Beer and Health Symposium on Beer, Silicon and Bone attended by industry.

Highlighted the importance of silicon and pave the way for future collaboration.
Year(s) Of Engagement Activity 2006
 
Description 6th International Conference on Silicon in Agriculture, Stockholm 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Large conference audience which followed on with many introductions and discussions with others in the field.

Following up with colleagues in the field with possible collaborations etc.
Year(s) Of Engagement Activity 2014
 
Description Alcohol & Health workshop - SABMiller 2010 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact talk to industry members at Alcohol & Health workshop on the interactions between silicon and estrogen

Continued relations with brewing industry
Year(s) Of Engagement Activity 2010
 
Description Arts Picturehouse - Film Education Event 2009 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Talk on 'Nanotechnology and the future of food' to a school audience at the Cambridge Arts Picturehouse as part of the Film Consortium's Event for the Cambridge Science Festival 2009.

None.
Year(s) Of Engagement Activity 2009
 
Description Ask the Nutritionist- 2009 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Talk within an 'Ask the Nutritionist' session at Brown's Field Community Centre, Cambridge on iron and iron deficiency.

Not known.
Year(s) Of Engagement Activity 2009
 
Description Beer: To your health- Washington DC -2006 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Talk given at the 'Beer: To Your Health' conference at Washington DC on 'Bone Health and Moderate Alcohol Consumption.' Updating industry on possible benefits.

Highlighted the importance of silicon and pave the way for future collaboration. Giving industry food for thought.
Year(s) Of Engagement Activity 2006
 
Description Bioavailability Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Paper Presentation
Geographic Reach International
Primary Audience Other audiences
Results and Impact Pereira DIA, Aslam MF, Powell JJ (2014) A cheap, safe and bioavailable novel iron supplement based on destabilised ferrihydrite nanoparticles: a review of findings. Bioavailability Conference. Brazil, Foz-do-Iguacu 12-14 May.


Established contacts with potential collaborators.
Year(s) Of Engagement Activity 2014
URL http://bioavailability2014.sban.org.br/
 
Description British Science Festival- 2009 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Talk at the British Science Festival at the University of Surrey on the role of trace elements in the diet.

Networking opportunities, e.g A fellow speaker was subsequenlty invited to HNR to present his talk at our internal seminar series - another was invited as a key note speaker at the 11th ISMIBM organised by our section in 2011.
Year(s) Of Engagement Activity 2009
 
Description Cafe Scientifique Nanofoods- 2009 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Talk entitled 'Shrinking down Nutrition: Nanofoods' at a Cafe Scientifique event.

Public very interested in Nanofoods legislation. Stimulated further discussions.
Year(s) Of Engagement Activity 2009
 
Description Chemnet Event- 2010 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach Local
Primary Audience Schools
Results and Impact Around 60 pupils attended the event to find out potential career opportunities following a degree in Chemistry.

Questions have been asked about work placement
Year(s) Of Engagement Activity 2010
 
Description Clinical Trace Element meeting (York) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact This was an invited talk at the Clinical Trace Element meeting in York (UK) on the 20th October 2016 jointly organised by the Supra-regional Assay Service for Trace Elements and Yorkshire/Trent Regional Association for Clinical Biochemistry and Laboratory Medicine. The talk was titled 'A novel approach for routine and direct high-precision Fe-isotope ratio analysis of whole blood by tandem mass spectrometry (ICP-MS/MS) for iron absorption studies'. The audience consisted of research students as well as managers and clinical biochemist that provide trace element analysis service.
Year(s) Of Engagement Activity 2016
 
Description Danish Brewers Association Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach International
Primary Audience Health professionals
Results and Impact This was a " Beer and Health" Symposium which was held in Copenhagen. The audience consisted of a variety of health professionals/scientists.

Led to further discussions
Year(s) Of Engagement Activity 2012
 
Description FSA - Nanotechnologies and Food Scanning event 2011 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Invited talk and presentation on Ingested Engineered Nanomaterials: Musings on Risk.

None
Year(s) Of Engagement Activity 2011
 
Description Federation of the Brewing and Soft Drink Industry- 2007 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Talk to the Federation of the Brewing and Soft Drink Industry on 'Moderate alcohol consumption: What is the message?' Making industry aware of the facts.

Continued relations with the brewing industry and making industry aware.
Year(s) Of Engagement Activity 2007
 
Description GI patient and IV iron Round table - Paris 2008 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Talk at the 'Does the GI Patient have a need for IV Iron?' Round Table Conference at Paris, France. Talk entitled 'Oral iron in IBD: Pros and cons.'

Sharing of information.
Year(s) Of Engagement Activity 2008
 
Description Gastroenterologists Meeting at Queen Mary's Hospital- 2008 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Gastroenterologists Meeting at Queen Mary's Hospital. Talk on Iron and IBD.

Sharing of knowledge and understanding of subject matter.
Year(s) Of Engagement Activity 2008
 
Description Gave a presentation at a collaborative meeting in Gottenberg, Sweden 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact I gave a talk entitled "The AMCP pathway and PD-L1 in Health and Disease: The Cambridge Experience" to a number of our collaborators which led to follow up discussions and meetings on our research.
Year(s) Of Engagement Activity 2015
 
Description Gave invited lecture to Bio-nano-materials conference in Faro, Portugal 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Gave presentation/talk to a wide variety of professionals i.e. scientists, industry, media which is hoped will spark further interest into our group research. It was also a good networking opportunity leading to further collaborations and contacts.
Year(s) Of Engagement Activity 2015
 
Description Gave invited lecture to the Royal Society at Chicheley Hall 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Gave talk entitled "Nanoparticles in the gastrointestinal tract: exposure and utilisation are normal physiological processes but imposters take advantage". This talk encouraged networking and introductions to like minded professionals.

Was a tool for further collaborations and interest from professionals world-wide.
Year(s) Of Engagement Activity 2014
 
Description Gave invited talk on nanoparticles at the International Fresenius Conference on Nanotechnology and Food, which took place in Cologne, Germany 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Gave talk entitled "Nanoparticles in the gastrointestinal tract covering a wide audience and a very good networking opportunities for further collaborations/interest.
Year(s) Of Engagement Activity 2013,2014,2015
 
Description Gave invited talk to an Oxford Translational Gastroenterology Unit at the John Radcliffe Hospital, Oxford 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Garnered interest in the subject mattter i.e. the aetiology of Crohn's disease: Peyer's Patches, Particles and PD-L1.

A number of requestes for furthe information.
Year(s) Of Engagement Activity 2014
 
Description Give e.V. (Berlin) 2011 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Invited talk on the comparative absorption of silicon from different foods and food supplements.

Article in an internal magazine by GIVE e.v. highlighting the importance of silicon.
Year(s) Of Engagement Activity 2011
 
Description Haemochromatosis Society AGM- 2009 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Talk for the Haemochromatosis Society AGM at the Royal Free Hospital, London. Talk entitled 'Type 1 hereditary haemochromatosis: does diet matter?'

None.
Year(s) Of Engagement Activity 2009
 
Description Health Professionals Talk - Toxicology Meeting 2010 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Health professionals
Results and Impact Presentation to health care professionals on the therapeutic uses of metals and minerals:risks.

further information/queries requested by some delegates who attended
Year(s) Of Engagement Activity 2010
 
Description Hughes Hall Cambridge Hat Club 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Dissemination of research activities as part of the University of Cambridge College community
Year(s) Of Engagement Activity 2015
 
Description I gave a talk at the IEEE - Nanomed Conference 2015, Hawaii, USA 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact I gave a talk entitled "Particle in a particle' strategy for effective delivery of oral iron" which garnered interest in our scientific colleagues on our work relating to the delivery of iron.
Year(s) Of Engagement Activity 2015
 
Description I was an invited speaker to the Eurotox 2015 conference held in Porto, Portugal 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact I gave an invited talk and presentation to a mixed audience entitled "Intestinal handling of mineral nanoparticles: friends or foes from food?" which followed on with many questions from the audience and was a good networking opportunity leading to follow up e-mails from scientists world-wide with an interest in Nano. Felt it was a worthwhile conference.
Year(s) Of Engagement Activity 2013,2014,2015
 
Description IDA and Gastroenterology meeting- 2006 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Challenges in Iron Deficiency Anaemia conference - Gastroenterology Meeting. Talk entitled 'Does oral iron really improve anaemic status in GI patients with GI disease?'

None.
Year(s) Of Engagement Activity 2006
 
Description IFR- 2009 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Talk to food industry professionals on past achievements and future ambitions of HNR.

wider knowledge within industry of MRC HNR and of the work of HNR and it's application to their work
Year(s) Of Engagement Activity 2009
 
Description International Workshop on Dairy and Gut Health- 2007 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Information sharing to health professionals and public/other audiences.

Provided insights into gut health.
Year(s) Of Engagement Activity 2007
 
Description Invitation to give a talk at the International Fresenius Conference on Nanotechnology and Food 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Sparked futher interest into the subject matter.

Good networking and possible future collaborations.
Year(s) Of Engagement Activity 2014
 
Description Invited Talk DP- Detection of Nanoparticles 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Workshop: Detection of Nanoparticles, Senftenburg, 29/11/2013 Germany.

Title Presentation: Nanoparticles in the gut: interactions with cells and bacteria.

Contact with potential collaborator on effect of nanoparticles on host-microbe interactions.
Year(s) Of Engagement Activity 2013
URL http://www.nanodetector.eu/lib/exe/fetch.php?media=poster-workshop_a4.pdf
 
Description Invited Talk DP- Kings College London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Dr Dora Pereira was invited as a Tea-Club Speaker by Kings College London- Nutritional Sciences Division.
Talk entitled: "Nanoparticulate Iron: a novel strategy to address iron deficiency anaemia?"
15/02/2012


Contact with collaborators and dissemination of research.
A new MSc research project was proposed by the 2 collaborator groups following this presentation and this has now been carried out and submitted to KCl.
Year(s) Of Engagement Activity 2012
 
Description Invited Talk DP-EuroNanoForum 2013 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Type Of Presentation Keynote/Invited Speaker
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact EuroNanoForum 2013, which took place in Dublin, on 18-20 June 2013. 'Safety evaluation and risk assessment of manufactured nanomaterials.' presented by Dora Pereira.

Received another invitation to present a guest lecture at for the FP7 project NANODETECTOR (www.nanodetector.eu) public workshop. The meeting "Detection of nanoparticles" will take place in Senftenberg at the Brandenburg University of Technology Cottbus-Senftenberg on 29th November 2013 from 10:00 - 15:00.
Year(s) Of Engagement Activity 2013
URL http://www.euronanoforum2013.eu/conference-information/
 
Description Invited Talk to Carlsburg, Copenhagan- 2011 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Talk and presentation on Beer and Health: Past, Present and Future.

Continued relations with the brewing industry and pave the way for future collaboration.
Year(s) Of Engagement Activity 2011
 
Description Invited talk DP- Coca-Cola Europe 2011 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Invited talk to Coca-Cola Europe on Iron fortification - Public Health Priorities, Biological Effects and beverage delivery systems.

Contact with the food Industry
Year(s) Of Engagement Activity 2011
 
Description Invited talk DP- FAO/WHO 2012 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Type Of Presentation Keynote/Invited Speaker
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Objectives
The purpose of the meeting was for FAO and WHO:
• To understand new developments in the area of nanotechnologies in food and agriculture;
• To present the newly developed FAO/WHO draft paper entitled "State of the art on the initiatives and activities relevant to risk assessment of nanotechnologies in the food and agriculture sectors" in order to obtain feedback from the experts and FAO/WHO colleagues from various divisions;
• To understand the objectives, scope and progress of other international organizations' initiatives; and
• To identify areas of future activities and the key roles for FAO and WHO.
Invited speakers
• Dr Dora Pereira, Medical Research Council (MRC) Cambridge, UK
• Dr Alessandro Chiodini, International Life Science Institute (ILSI) Europe
• Dr Manfred Lützow, FAO/WHO consultant
• Ms Mar Gonzalez the Organization for Economic Cooperation and Development (OECD) Working Party on Manufactured Nanomaterials (WPMN) Secretariat



• It was strongly recommended by the participants that FAO and WHO should continue the effort to develop a decision tree with a tiered approach for risk assessment of nanomaterials. It is important for FAO and WHO to consider the specific point that nano will never be consumed in large amount, therefore traditional toxicological assessment (that use extremely large amount of substance) would not be realistic. FAO has produced a report of the meeting.
Year(s) Of Engagement Activity 2012
 
Description Invited talk DP- Nestle 2012 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Invited presentation at the Nestle Research Centre in Lausanne, CH entitled "Nanoparticulate Iron: a novel strategy to address iron deficiency anaemia?", Dr Dora Pereira 19/03/2012. Twenty Nestle researchers attended the presentation and discussions followed regarding the possibility of the NRC of testing the novel iron compounds developed at MRC HNR for food fortification.

Nestle has shown an interest in the MRC HNR-developed novel iron materials for food fortification. Discussions are now in place between MRC HNR and Nestle' for testing of the compounds at the NRC.
Year(s) Of Engagement Activity 2012
 
Description Invited talk given to group (Experimental Cancer Therapeutics, University of Cambridge) at Addenbrooke's Hospital, Cambridge 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Gave talk entitled "Exploiting Silicate Chemistry in Cancer Therapy" to researchers.

Stimulated questions and further collaborations.
Year(s) Of Engagement Activity 2014
 
Description Invited talk to possible commericial Partner 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact This was an exploratory meeting with a possible commercial partner for the BMR group's IP. Very positive follow on discussions are on-going.
Year(s) Of Engagement Activity 2015
 
Description Invited talk to the Oxford Clinical Trial Service Unit, John Radcliffe Hospital, Oxford 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact This talk came about after my presentation at the MRC Inaugural Programme Leaders Day which took place early in 2015. There was much interest on our work on iron and effective phosphate binding and novel therapeutics.
Year(s) Of Engagement Activity 2015
 
Description Iron Club Seminar - Kings College London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Tea Club lecture to the Kings College Iron Club. Audience was mainly scientists working in the iron field.
Year(s) Of Engagement Activity 2015
 
Description MRC HNR centenary open day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact N/A
Year(s) Of Engagement Activity 2013
 
Description MRC Inaugural Programme Leaders Day 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Part of the Showcase for the MRC Translation Group and will precede a strategic update on the activities within the translation group. Networking with other MRC Programme Leaders within other MRC Units. This also led to another invitation to give a talk to the Oxford Clinical Trial Service Unit, John Radcliffe Hospital, Oxford.
Year(s) Of Engagement Activity 2015
 
Description Media Interviews - Beer and Health 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact 1 media interview on the topic of nutritional benefits of drinking beer, resulting in quote in leading national newspaper.

Continuing to build strong relationship with the media and highlighting HNR's profile and the work and research of the unit. Requests for further information from journalists, researchers, policy makers and health care professionals have resulted in a number of cases.
Year(s) Of Engagement Activity 2012
 
Description Media Release - Beer & Silicon- 2009/2010 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Media release on the potential benefit of moderate beer consumption

wide spread pick up of release across national media
Year(s) Of Engagement Activity 2009,2010
 
Description Membership of Task Group DP- Nanorelease ILSI 2012 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Type Of Presentation Workshop Facilitator
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact This task group initiative and workshop seeks to advance the state of the science of measurement methods characterizing the release of ingested engineered nanomaterials from food and absorption by the body by producing white papers. Dora Pereira will be co-author of the white paper on 'Gastrointestinal luminal factors affecting nanomaterials'.

None so far. Co-authorship of a white paper is expected in early 2013.
Year(s) Of Engagement Activity 2012
 
Description Mighty Minerals- CSF 2010 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Development of a minerals focused activity stand for part of Cambridge Science Festival

a number of teachers took away the mineral cards developed to utilise the use of these in the classroom
Year(s) Of Engagement Activity 2010
 
Description Nanotechnology: NanoIron-CSF 2013 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact N/A
Year(s) Of Engagement Activity 2013
 
Description New Scientist article on iron nanoparticle research 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Quote for article in New Scientist magazine on topic of iron nanoparticle research which increased awareness of research and stimulated thinking

Not known
Year(s) Of Engagement Activity 2014
 
Description Nutritionists In Industry-1 2010 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Health professionals
Results and Impact Talk to nutritionists in Industry: "Understanding dietary and fortificant Iron: the devil is in the detail"

contact with food industry for future studies
Year(s) Of Engagement Activity 2010
 
Description Nutritionists In Industry-2 2010 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Health professionals
Results and Impact Talk for Nutritionists in Industry: "Iron supplementation and fortification: do the benefits outweigh the risks?"

further contact with the food industry
Year(s) Of Engagement Activity 2010
 
Description Presentation to commercial partner 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Talk & Presentation - Further to this and other meetings we now have a commercial partner for our developed IP.
Year(s) Of Engagement Activity 2015
 
Description Primary school visit and a talk to the general public 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Engagement sessions with a local primary school and the general public as part of Science Week 2017. These are workshop based sessions on germs.
Year(s) Of Engagement Activity 2017
 
Description Radio Interview - Iron speciation CSF 2010 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact radio interview on the iron forms being demonstarted at Mighty Minerals stand of Cambridge Science Festival

Interview went out on local BBC radio station
Year(s) Of Engagement Activity 2010
 
Description Radio Interview Nanotechnology- 2008 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Radio interview on BBC Radio 4 on 'Nanotechnology.'

None.
Year(s) Of Engagement Activity 2008
 
Description Radio Interview- Iron in the Diet- 2008 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Radio interview on BBC Radio Cambridgeshire on 'Iron in the diet and volunteer recruitment.'

Helped recruite volunteer for our novel iron preparation study
Year(s) Of Engagement Activity 2008
 
Description Roundtable Discussion- strategies for treating anaemia in pregnancy 2011 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach National
Primary Audience Health professionals
Results and Impact Dora pereira was invited to participate in the Working Group discussion on strategies for treating anaemia in pregnancy: Presented talk on Iron deficiency anaemia in pregnancy "Challenges in Iron Deficiency Anaemia. Working group consisted of nurses, midwifes, medical doctors, academia and industry.

None
Year(s) Of Engagement Activity 2011
 
Description SMC Briefing- 2009 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Media (as a channel to the public)
Results and Impact Science Media Centre (SMC) Briefing on Nanoparticles to the Daily Mail, the Mirror and the Press Association.

None.
Year(s) Of Engagement Activity 2009
 
Description SMI Nutraceuticals and Functional Foods- 2010 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Health professionals
Results and Impact Presentation given at the SMi Nutraceuticals and Functional Foods Conference in London. Talk entitled 'Nanotechnology in foods: why are we shrinking down nutrition.'

Networking opportunities with fellow speakers
Year(s) Of Engagement Activity 2010
 
Description SMi Nutraceuticals and Functional Foods- 2009 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Health professionals
Results and Impact Presentation given at the SMi Nutraceuticals and Functional Foods Conference in London. Talk entitled 'Nanotechnology in foods: Shrinking down nutrition.'

Invited for a talk the following year.
Year(s) Of Engagement Activity 2009
 
Description School Visit: Minerals and Health 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach Local
Primary Audience Schools
Results and Impact Talk to 60 pupils from a local primary school (Year 5) on minerals and health with a lab demonstration with ferrofluid.

The students were very interested in the hands-on activity.
Year(s) Of Engagement Activity 2014
 
Description School visits to HNR- 2009 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Small presentations describing the work of the Biomineral Research group as part of a larger presentation on the work of the whole Unit to school-aged students when visiting MRC Human Nutrition Research.

None.
Year(s) Of Engagement Activity 2009
 
Description Schools Masterclass- 2010 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Talk from PhD student on her study.

Continued participation in schools masterclass has been requested
Year(s) Of Engagement Activity 2010
 
Description Seminar at Thermo Scientific Laboratories, Hemel Hempstead 2011 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Talk and presentation re: Trace Element Analysis in Nutritional Studies (Solutions for Clinical and Life Science Analysis).

Networking with other users of ICP-MS techniques
Year(s) Of Engagement Activity 2011
 
Description Shepherd Neame Hop Blessing- 2007 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Talk at the Shepherd Neame Hop Blessing entitled: 'Silicon - a nutrient in beer?'

Highlighted the importance of silicon. Continued relations with the brewing industry and pave the way for future collaboration..
Year(s) Of Engagement Activity 2007
 
Description Talk to primary school children on Nutrition 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach Local
Primary Audience Schools
Results and Impact 60 year 1 pupils attended the talk and hands-on activities to illustrate the importance of making healthy food choices to remain healthy. This was part of their year 1 topic on 'Our bodies and Health'.

School asked for this activity to be repeated next year.
Year(s) Of Engagement Activity 2013
 
Description Talk to primary school children on Nutrition 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation Keynote/Invited Speaker
Geographic Reach Local
Primary Audience Schools
Results and Impact Two visits to primary school in local area to talk about nutrition.

Was asked to return to give second talk.

Engaged young children in the topic of nutrition.
Year(s) Of Engagement Activity 2012
 
Description Talk to the Department of Veterinary Medicine (University of Cambridge) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact This talk was to introduce the work conducted by the BMR group to the Head of Department and other staffs and students of the Department of Veterinary Medicine (University of Cambridge) as part of the propose transfer of the group into the department.
Year(s) Of Engagement Activity 2016
 
Description Talk/Presentation to Hughes Hall, University of Cambridge 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Gave a presentation to the College that I am a Fellow at (Hughes Hall, University of Cambridge) to garner more interest from the postgraduate students resulting in more students deciding to pursue research careers to e.g. lives saved, research etc.
Year(s) Of Engagement Activity 2015
 
Description Tea Club Talk/Presentation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Gave talk to MRC Unit stimulating interest and questions.

Asked to give further talks at other institutions.
Year(s) Of Engagement Activity 2014
 
Description Television Interview BBC Look East on Iron - 2008 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Television interview for BBC Look East on 'Iron in the diet and volunteer recruitment.'

A scientist from University of cambridge contacted us at the issues of this interview to set up a collaboration on iron in plant based food - this collaboration has already led to 3 Master thesis between us and to a grant applciation to BBSRC DRINC2 which has been awarded in 2014.
Year(s) Of Engagement Activity 2008
 
Description The Brewers of Europe, Brussels- 2011 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Talk and presentation on Silicon, Ethanol and Connective Tissue Health: A case for moderate beer consumption?

Met potential future collaborators. Continued relations with the brewing industry and pave the way for future collaboration.
Year(s) Of Engagement Activity 2011
 
Description University of Cambridge Lectures 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Type Of Presentation Keynote/Invited Speaker
Geographic Reach National
Primary Audience Undergraduate students
Results and Impact +300 students attend these lectures every year.

+300 students attend these lectures every year as part of their medical training.
Year(s) Of Engagement Activity 2006,2007,2008,2009,2010
 
Description oral presentation 5th Zing Bionanomaterials Conference 2015 (Algarve) -Carlos Bastos 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact presentation on novel antimicrobials to predominantly academic audience
Year(s) Of Engagement Activity 2015
 
Description oral presentation 5th Zing Bionanomaterials Conference 2015 (Algarve) -Nuno faria 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact presentation on novel antimicrobials to predominantly academic audience
Year(s) Of Engagement Activity 2015