Clinical MR Imaging
Lead Research Organisation:
MRC London Institute of Medical Sciences
Abstract
Abstract not currently available
Technical Summary
Neuropsychiatry: A grey scale based technique is used for precise registration of serial magnetic resonance images of the brain in order to detect small differences. These can be quantified. It provides objective measures of disease progression and response to treatment. For example, the rate of increase in ventricular size is about five times greater than normal in Alzheimers disease. A parallel study is being conducted with the MRC Cyclotron Unit to ascertain the effects of radiotherapy and Temozolamide.
The technique provides an objective method for studying disease progression as well as studying the effectiveness of treatment. It allows new treatments to be evaluated with fewer patients.
The technique provides an objective method for studying disease progression as well as studying the effectiveness of treatment. It allows new treatments to be evaluated with fewer patients.
People |
ORCID iD |
| Joseph V Hajnal (Principal Investigator) |
| Description | European Society for Pediatric Research Consolidator Grant |
| Amount | € 75,000 (EUR) |
| Organisation | European Society Paediatric Research |
| Sector | Charity/Non Profit |
| Country | Switzerland |
| Start | 02/2018 |
| End | 02/2019 |
| Description | IEH Grant |
| Amount | £10,000,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 03/2021 |
| Description | MRC Strategic Grant |
| Amount | £7,287,951 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2012 |
| End | 03/2016 |
| Description | PROJECT GRANT |
| Amount | £174,035 (GBP) |
| Funding ID | GN2630 |
| Organisation | Action Medical Research |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 10/2020 |
| Description | Strategic Grant - the Develping Brain |
| Amount | £7,278,954 (GBP) |
| Funding ID | MR/K006355/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2012 |
| End | 03/2016 |
| Description | Synergy Grant |
| Amount | € 14,900,000 (EUR) |
| Organisation | European Research Council (ERC) |
| Sector | Public |
| Country | European Union (EU) |
| Start | 09/2013 |
| End | 09/2019 |
| Description | Wellcome Centre |
| Amount | £12,100,395 (GBP) |
| Funding ID | 203148/Z/16/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2017 |
| End | 07/2022 |
| Description | Wellcome Trust Equipment Grant |
| Amount | £633,226 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2008 |
| End | 03/2012 |