Basse Health and Demographic Surveillance System
Lead Research Organisation:
MRC Unit, The Gambia
Abstract
By virtue of the size of the population it covers, the Basse HDSS offers opportunities to understand the dynamics and risk factors associated with common infectious diseases prevailing in a typical Sub-Saharan African setting characterised by poverty and limited access to health care facilities and services. Prospective follow up of the population through 4-monthly household demographic (and biennial socio-economic) updates determines the trends in the death rate in different age groups of the population; and the conduct of verbal autopsies for as many deaths as possible ascertains the probable causes of death. The process therefore enhances our understanding of the health and socio-economic factors that that drive and sustain the determinants of disease-specific morbid episodes and mortality, especially infectious diseases among children.
Technical Summary
The Basse Health and Demographic Surveillance System (BHDSS) was established in July 2007, primarily to support Basse’s participation in the Global Enteric Multicentre Study (GEMS) and the ongoing Pneumococcal Surveillance Project (PSP). It covers a population of about 170,000 in 219 settlements in the Fulladu East and Kantora Districts of the Upper River Region of The Gambia, a setting typical of much of rural Sub-Saharan and with a high burden of communicable and preventable diseases. In addition to the GEMS and PSP projects, it hosts and facilitates the implementation of a range of other projects and studies.
The BHDSS, with a similar operational design as the Farafenni HDSS, constitutes a potential valuable resource to establish benchmarks and monitor progress towards the achievement of post-2015 global and regional health indicators that the international community will be expected to set.
Specific strategies to be adopted to maximise the scientific output of the BHDSS include:
• Potential linkage of DSS data with Basse Major Health Centre records (in recognition of its potential upgrading to a District Hospital), thus broadening the scope for medical research to include, among other things, disease-specific morbidity burden estimation for both communicable and non-communicable diseases, and their respective impact on quality of life.
• Enhance capacity to support the placement of PhD students in the fields of Demography, Epidemiology, Sociology, etc, and build multi-disciplinary capacity for optimal utilisation of the data generated by the platform.
• Fully engage government stakeholders in the utilisation of the platform database to inform public health policy formulation and review; as well as generating the necessary evidence base required to guide rational health care delivery planning and resource allocation.
The BHDSS, with a similar operational design as the Farafenni HDSS, constitutes a potential valuable resource to establish benchmarks and monitor progress towards the achievement of post-2015 global and regional health indicators that the international community will be expected to set.
Specific strategies to be adopted to maximise the scientific output of the BHDSS include:
• Potential linkage of DSS data with Basse Major Health Centre records (in recognition of its potential upgrading to a District Hospital), thus broadening the scope for medical research to include, among other things, disease-specific morbidity burden estimation for both communicable and non-communicable diseases, and their respective impact on quality of life.
• Enhance capacity to support the placement of PhD students in the fields of Demography, Epidemiology, Sociology, etc, and build multi-disciplinary capacity for optimal utilisation of the data generated by the platform.
• Fully engage government stakeholders in the utilisation of the platform database to inform public health policy formulation and review; as well as generating the necessary evidence base required to guide rational health care delivery planning and resource allocation.
Organisations
- MRC Unit, The Gambia, Gambia (Lead Research Organisation)
- National Institute of Allergy and Infectious Diseases (NIAID) (Collaboration)
- African Academy of Sciences (Collaboration)
- International Network for the Demographic Evaluation of Populations and Their Health (INDEPTH) (Collaboration)
- Wellcome Trust, LONDON (Collaboration)
- Bill and Melinda Gates Foundation (Collaboration)
- World Health Organization (WHO) (Collaboration)
- Medical Research Council (Collaboration)
- Medical Research Council of South Africa (MRC) (Collaboration)
People |
ORCID iD |
Momodou Jasseh (Principal Investigator) |
Publications


Hossain MJ
(2013)
Serogroup W135 meningococcal disease, The Gambia, 2012.
in Emerging infectious diseases

Hossain MJ
(2019)
Cryptosporidium infection in rural Gambian children: Epidemiology and risk factors.
in PLoS neglected tropical diseases

Kwambana BA
(2014)
High genotypic diversity among rotavirus strains infecting Gambian children.
in The Pediatric infectious disease journal

Mackenzie GA
(2015)
Increased disease due to Haemophilus influenzae type b: population-based surveillance in eastern Gambia, 2008-2013.
in The Pediatric infectious disease journal

Mackenzie GA
(2016)
Effect of the introduction of pneumococcal conjugate vaccination on invasive pneumococcal disease in The Gambia: a population-based surveillance study.
in The Lancet. Infectious diseases

Quattrochi J
(2015)
Spatial analysis of under-5 mortality and potential risk factors in the Basse Health and Demographic Surveillance System, the Gambia.
in Tropical medicine & international health : TM & IH


Saha D
(2013)
Health Care Utilization and Attitudes Survey: understanding diarrheal disease in rural Gambia.
in The American journal of tropical medicine and hygiene
Description | African Population Cohorts Consortium (APCC) |
Organisation | African Academy of Sciences |
Country | Kenya |
Sector | Charity/Non Profit |
PI Contribution | I was among a few senior African scientists/leaders selected to chair and lead discussions in a scoping workshop/meeting to agree and shape a vision for a multinational network of large cohorts. The purpose is to set up the African Population Cohorts Consortium (APCC) with a view to responding to the dearth of health and social data, which is hampering progress in addressing the increasing burden of non-communicable diseases along the high levels of infectious diseases and malnutrition in the continent. I chaired all sessions relating to Demography and Epi-demographic core metrics. I was also selected in a team tasked to develop a white paper through a series of post-workshop consultations for consideration by the interested funders.. |
Collaborator Contribution | Through the Wellcome Trust, the team of funders organised and brought together experts working in the African continent for the scoping workshop. WT also coordinated the preparation of the white paper. |
Impact | The White Paper is yet to be published. |
Start Year | 2020 |
Description | African Population Cohorts Consortium (APCC) |
Organisation | Bill and Melinda Gates Foundation |
Country | United States |
Sector | Charity/Non Profit |
PI Contribution | I was among a few senior African scientists/leaders selected to chair and lead discussions in a scoping workshop/meeting to agree and shape a vision for a multinational network of large cohorts. The purpose is to set up the African Population Cohorts Consortium (APCC) with a view to responding to the dearth of health and social data, which is hampering progress in addressing the increasing burden of non-communicable diseases along the high levels of infectious diseases and malnutrition in the continent. I chaired all sessions relating to Demography and Epi-demographic core metrics. I was also selected in a team tasked to develop a white paper through a series of post-workshop consultations for consideration by the interested funders.. |
Collaborator Contribution | Through the Wellcome Trust, the team of funders organised and brought together experts working in the African continent for the scoping workshop. WT also coordinated the preparation of the white paper. |
Impact | The White Paper is yet to be published. |
Start Year | 2020 |
Description | African Population Cohorts Consortium (APCC) |
Organisation | Medical Research Council (MRC) |
Country | United Kingdom |
Sector | Public |
PI Contribution | I was among a few senior African scientists/leaders selected to chair and lead discussions in a scoping workshop/meeting to agree and shape a vision for a multinational network of large cohorts. The purpose is to set up the African Population Cohorts Consortium (APCC) with a view to responding to the dearth of health and social data, which is hampering progress in addressing the increasing burden of non-communicable diseases along the high levels of infectious diseases and malnutrition in the continent. I chaired all sessions relating to Demography and Epi-demographic core metrics. I was also selected in a team tasked to develop a white paper through a series of post-workshop consultations for consideration by the interested funders.. |
Collaborator Contribution | Through the Wellcome Trust, the team of funders organised and brought together experts working in the African continent for the scoping workshop. WT also coordinated the preparation of the white paper. |
Impact | The White Paper is yet to be published. |
Start Year | 2020 |
Description | African Population Cohorts Consortium (APCC) |
Organisation | Medical Research Council of South Africa (MRC) |
Country | South Africa |
Sector | Public |
PI Contribution | I was among a few senior African scientists/leaders selected to chair and lead discussions in a scoping workshop/meeting to agree and shape a vision for a multinational network of large cohorts. The purpose is to set up the African Population Cohorts Consortium (APCC) with a view to responding to the dearth of health and social data, which is hampering progress in addressing the increasing burden of non-communicable diseases along the high levels of infectious diseases and malnutrition in the continent. I chaired all sessions relating to Demography and Epi-demographic core metrics. I was also selected in a team tasked to develop a white paper through a series of post-workshop consultations for consideration by the interested funders.. |
Collaborator Contribution | Through the Wellcome Trust, the team of funders organised and brought together experts working in the African continent for the scoping workshop. WT also coordinated the preparation of the white paper. |
Impact | The White Paper is yet to be published. |
Start Year | 2020 |
Description | African Population Cohorts Consortium (APCC) |
Organisation | National Institute of Allergy and Infectious Diseases (NIAID) |
Country | United States |
Sector | Public |
PI Contribution | I was among a few senior African scientists/leaders selected to chair and lead discussions in a scoping workshop/meeting to agree and shape a vision for a multinational network of large cohorts. The purpose is to set up the African Population Cohorts Consortium (APCC) with a view to responding to the dearth of health and social data, which is hampering progress in addressing the increasing burden of non-communicable diseases along the high levels of infectious diseases and malnutrition in the continent. I chaired all sessions relating to Demography and Epi-demographic core metrics. I was also selected in a team tasked to develop a white paper through a series of post-workshop consultations for consideration by the interested funders.. |
Collaborator Contribution | Through the Wellcome Trust, the team of funders organised and brought together experts working in the African continent for the scoping workshop. WT also coordinated the preparation of the white paper. |
Impact | The White Paper is yet to be published. |
Start Year | 2020 |
Description | African Population Cohorts Consortium (APCC) |
Organisation | Wellcome Trust |
Country | United Kingdom |
Sector | Charity/Non Profit |
PI Contribution | I was among a few senior African scientists/leaders selected to chair and lead discussions in a scoping workshop/meeting to agree and shape a vision for a multinational network of large cohorts. The purpose is to set up the African Population Cohorts Consortium (APCC) with a view to responding to the dearth of health and social data, which is hampering progress in addressing the increasing burden of non-communicable diseases along the high levels of infectious diseases and malnutrition in the continent. I chaired all sessions relating to Demography and Epi-demographic core metrics. I was also selected in a team tasked to develop a white paper through a series of post-workshop consultations for consideration by the interested funders.. |
Collaborator Contribution | Through the Wellcome Trust, the team of funders organised and brought together experts working in the African continent for the scoping workshop. WT also coordinated the preparation of the white paper. |
Impact | The White Paper is yet to be published. |
Start Year | 2020 |
Description | Cause of Death Determination |
Organisation | International Network for the Demographic Evaluation of Populations and Their Health (INDEPTH) |
Country | Ghana |
Sector | Charity/Non Profit |
PI Contribution | Contribute Farafenni cause-of-death data for multi-site studies. Co-ordinated the analysis of HIV-attributable mortality in adults in four West African HDSS sites using verbal autopsy data. |
Collaborator Contribution | Development of a computer algorithm (InterVA) to interpret verbal autopsies. Development of standard verbal autopsy questionnaires. |
Impact | International seminar presentations. |
Start Year | 2011 |
Description | Cause of Death Determination |
Organisation | World Health Organization (WHO) |
Department | Health Metrics Network (HMN) |
Country | Switzerland |
Sector | Charity/Non Profit |
PI Contribution | Contribute Farafenni cause-of-death data for multi-site studies. Co-ordinated the analysis of HIV-attributable mortality in adults in four West African HDSS sites using verbal autopsy data. |
Collaborator Contribution | Development of a computer algorithm (InterVA) to interpret verbal autopsies. Development of standard verbal autopsy questionnaires. |
Impact | International seminar presentations. |
Start Year | 2011 |
Description | Rationale for a Vaccine efficacy trial during Public Health Emergencies |
Organisation | World Health Organization (WHO) |
Country | Global |
Sector | Public |
PI Contribution | Participation in a series of meetings aimed at developing a clinical toolbox for vaccine trials during public health emergencies. Oral presentation at a joint WHO & NIAID (USA) Scientific Consultation on Zika Virus Vaccine Development, explaining the process adopted to develop the WHO R&D blueprint for action to prevent epidemics. |
Collaborator Contribution | Facilitation of my participation in all meetings and consultations. |
Impact | Work is still progressing on the WHO R&D blueprint for action to prevent epidemics. |
Start Year | 2016 |
Description | WHO Ad Hoc Expert consultation on Non-Specific Effects of Vaccines |
Organisation | World Health Organization (WHO) |
Department | Department of Immunization, Vaccines and Biologicals |
Country | Global |
Sector | Public |
PI Contribution | Participation in a series of workshops to develop a multi-site research protocol to investigate the impact of BCG on survival in the first 14 weeks of life, as well as in infancy. The Basse Health and Demographic Surveillance System is being put forward for consideration as a potential study site. |
Collaborator Contribution | Cover travel and board for all meetings I have attended. |
Impact | Draft research protocol on randomized controlled trials of early versus late BCG vaccination. It is yet to be finalised and submitted to the WHO SAGE advisory committee for consideration and approval. |
Start Year | 2016 |