Lifecourse Determinants of Bone and Joint Disease
Lead Research Organisation:
MRC Lifecourse Epidemiology Unit
Abstract
The mission of the MRC Lifecourse Epidemiology Unit is to provide a centre of excellence which uses epidemiological methods to promote human health by delineating the environmental and occupational causes throughout the lifecourse of: (1) chronic musculoskeletal disorders (osteoporosis, osteoarthritis and sarcopenia); and (2) metabolic disorders (diabetes mellitus, obesity and cardiovascular disease). Through understanding these causes, we aim to develop population-based and high risk preventive strategies against these disorders. This programme will explore the origins of osteoporosis and its related fractures in the elderly, as well as osteoarthritis. These are the two commonest bone and joint disorders worldwide.
Technical Summary
Objectives: To (a) understand better the mechanisms which underlie the developmental origins of osteoporosis and other musculoskeletal disorders; and (b) develop intervention studies aimed at modifying later disease risk through nutritional and other interventions targeted at critical periods of development. Research proposals: The programme will address the developmental origins of osteoporotic fracture from molecule to population, using observational as well as interventional studies. Follow-up of participants in the Hertfordshire and Helsinki cohort studies will determine the growth trajectories of individuals at later risk of fracture, and explore the impact of these trajectories on bone size, geometry, mineral content, and volumetric density; the genetic contribution to these aspects of fracture risk will be studied through genome-wide screening as part of large international consortia. Further follow-up of children included in the Southampton Womens Survey will elucidate the parental influences on skeletal development during peri-conception, pregnancy and early postnatal life. Follow-up of these children through ages 6 and 8 years will extend our understanding of the relationship between maternal 25-hydroxyvitamin D status during pregnancy and childhood skeletal size, geometry and volumetric density. Our studies will permit exploration of interactions between prenatal and postnatal environmental influences such as physical activity (assessed using accelerometry), and diet (using questionnaires and biomarkers). Epigenetic mechanisms underlying the observed relationships between early environment and later bone health will be explored using samples of umbilical cord and placenta obtained from deliveries within SWS; DNA methylation status of key genes engaged in calcium transport, and maternal stress, will be related to childhood bone mass. A centrepiece of the programme will be the first randomised controlled trial to investigate whether supplementation of vitamin D during pregnancy serves to optimise skeletal development in the offspring (MAVIDOS). This aetiological trial will encompass sub-studies addressing intermediary outcome measures and the impact of vitamin D supplementation on other systems (body composition, immune function and respiratory development). Interventions to prevent osteoporotic fracture later in the lifecourse will be evaluated as part of the programme. Thus, in the MRC SCOOP trial, we test a novel methodology for risk stratification developed by the WHO in a large (n=11,500), pragmatic, randomised controlled trial. Finally, linkage with the NIHR Biomedical Research Unit in Musculoskeletal Science, University of Oxford, will permit development of a research theme addressing the lifecourse epidemiology of osteoarthritis; we shall study determinants of initiation and progression of this disorder, risk factors for arthroplasty failure, and the role of vitamin D in retarding the progression of OA. Impact: Musculoskeletal disorders have enormous health and economic impacts on society. Our research programme will permit the development of novel public health strategies to improve skeletal health throughout the lifecourse, and reduce osteoporotic fractures in future generations. Greater understanding of the epidemiology of osteoarthritis (the commonest joint disorder worldwide) will contribute to parallel strategies that reduce the incidence and morbidity associated with this disorder.
Organisations
- MRC Lifecourse Epidemiology Unit (Lead Research Organisation)
- Royal North Shore Hospital and Kolling Institute (Collaboration)
- University of Gothenburg, Sweden (Collaboration)
- VU University Medical Center (Collaboration)
- University of Edinburgh, United Kingdom (Collaboration)
- Diakonhjemmet Hospital (Collaboration)
- University College Dublin, Ireland (Collaboration)
- University of Amsterdam (Collaboration)
- University of Cambridge (Collaboration)
- University of Liverpool, United Kingdom (Collaboration)
- University of Helsinki, Finland (Collaboration)
- Northwestern University (Collaboration)
- University of Southern Denmark, Denmark (Collaboration)
- University of Oxford, United Kingdom (Collaboration)
- University of Leuven (Collaboration)
- Cedars-Sinai Medical Center (Collaboration)
- University of Bristol, United Kingdom (Collaboration)
- Maastricht University (UM) (Collaboration)
- GlaxoSmithKline (GSK) (Collaboration)
- Ludwig Maximilians University Munich (Collaboration)
- University Hospital Southampton NHS Foundation Trust, Southampton (Collaboration)
- World Health Organization (WHO) (Collaboration)
- University of Lorraine (Collaboration)
- University of East Anglia, United Kingdom (Collaboration)
- University of Birmingham, United Kingdom (Collaboration)
- University of Aberdeen, United Kingdom (Collaboration)
- Lancaster University (Collaboration)
- University of Southampton, United Kingdom (Collaboration)
- University College London, United Kingdom (Collaboration)
- Utrecht University (Collaboration)
- Autonomous University of Barcelona (UAB) (Collaboration)
- Queen Mary, University of London, United Kingdom (Collaboration)
- National Institute of Health and Medical Research (INSERM) (Collaboration)
- University of South Carolina, United States (Collaboration)
- University of Bergen, Norway (Collaboration)
- University of Ottawa, Canada (Collaboration)
- University of Sheffield, United Kingdom (Collaboration)
- University of Maryland, United States (Collaboration)
- Genetic Factors for Osteoporosis Consortium (GEFOS) (Collaboration)
- University of Oslo, Norway (Collaboration)
- University of Florence (Collaboration)
- Zoology Ecology and Plant Science (Collaboration)
- Imperial College London, United Kingdom (Collaboration)
- The Wellcome Trust Sanger Institute (Collaboration)
- Erasmus University Rotterdam (EUR) (Collaboration)
- Medical Research Council (Collaboration)
- University of York, United Kingdom (Collaboration)
- University of Geneva, Switzerland (Collaboration)
- McGill University, Canada (Collaboration)
- Guy's and St Thomas' NHS Foundation Trust, London (Collaboration)
- Free University of Amsterdam (Collaboration)
- University of Manchester, Manchester, United Kingdom (Collaboration)
- Johns Hopkins University, United States (Collaboration)
People |
ORCID iD |
| Cyrus Cooper (Principal Investigator) |
Publications
Varanasi SS
(2011)
Lack of association of bone morphogenetic protein 2 gene haplotypes with bone mineral density, bone loss, or risk of fractures in men.
in Journal of osteoporosis
Pouwels S
(2011)
Use of proton pump inhibitors and risk of hip/femur fracture: a population-based case-control study.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Prieto-Alhambra D
(2011)
Changes in hip fracture rate before and after total knee replacement due to osteoarthritis: a population-based cohort study.
in Annals of the rheumatic diseases
Bazelier MT
(2011)
The risk of fracture in patients with multiple sclerosis: the UK general practice research database.
in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Sambrook PN
(2011)
Predicting fractures in an international cohort using risk factor algorithms without BMD.
in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Cooper C
(2011)
Secular trends in the incidence of hip and other osteoporotic fractures.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Prieto-Alhambra D
(2011)
Fracture risk before and after total hip replacement in patients with osteoarthritis: potential benefits of bisphosphonate use.
in Arthritis and rheumatism
Muraki S
(2011)
Association of vitamin D status with knee pain and radiographic knee osteoarthritis.
in Osteoarthritis and cartilage
Javaid MK
(2011)
Growth in childhood predicts hip fracture risk in later life.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Leib ES
(2011)
Official Positions for FRAX(®) clinical regarding glucocorticoids: the impact of the use of glucocorticoids on the estimate by FRAX(®) of the 10 year risk of fracture from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(®).
in Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
Rizzoli R
(2011)
Adverse reactions and drug-drug interactions in the management of women with postmenopausal osteoporosis.
in Calcified tissue international
Linaker C
(2011)
The burden of sickness absence from musculoskeletal causes in Great Britain.
in Occupational medicine (Oxford, England)
Duncan EL
(2011)
Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk.
in PLoS genetics
Fisk CM
(2011)
Breastfeeding and reported morbidity during infancy: findings from the Southampton Women's Survey.
in Maternal & child nutrition
Shaheen SO
(2011)
Relationship of vitamin D status to adult lung function and COPD.
in Thorax
Pazianas M
(2011)
Atrial fibrillation and the use of oral bisphosphonates.
in Therapeutics and clinical risk management
Broy SB
(2011)
Official Positions for FRAX® clinical regarding rheumatoid arthritis from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®.
in Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
Vasikaran S
(2011)
International Osteoporosis Foundation and International Federation of Clinical Chemistry and Laboratory Medicine position on bone marker standards in osteoporosis.
in Clinical chemistry and laboratory medicine
Rizzoli R
(2011)
Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Judge A
(2011)
Pre-operative expectation predicts 12-month post-operative outcome among patients undergoing primary total hip replacement in European orthopaedic centres.
in Osteoarthritis and cartilage
Soler Artigas M
(2011)
Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function.
in American journal of respiratory and critical care medicine
Roberts HC
(2011)
A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach.
in Age and ageing
Dennison E
(2011)
Osteoporosis in 2010: building bones and (safely) preventing breaks.
in Nature reviews. Rheumatology
Baird J
(2011)
Does birthweight predict bone mass in adulthood? A systematic review and meta-analysis.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Wahl DA
(2011)
Clinicians need to treat underlying osteoporosis.
in BMJ (Clinical research ed.)
Roux C
(2011)
Prevalence of osteoporosis and fractures among women prescribed osteoporosis medication in five European countries: the POSSIBLE EU study.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Blank RD
(2011)
Official Positions for FRAX® clinical regarding prior fractures from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®.
in Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
Gale CR
(2011)
Neighbourhood environment and positive mental health in older people: the Hertfordshire Cohort Study.
in Health & place
Fisher BA
(2012)
Heterogeneity of anticitrullinated peptide antibodies and response to anti-tumor necrosis factor agents in rheumatoid arthritis.
in The Journal of rheumatology
Harvey NC
(2012)
Physical activity, calcium intake and childhood bone mineral: a population-based cross-sectional study.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Crozier SR
(2012)
Maternal vitamin D status in pregnancy is associated with adiposity in the offspring: findings from the Southampton Women's Survey.
in The American journal of clinical nutrition
Cooper C
(2012)
Osteoporosis risk assessment.
in BMJ (Clinical research ed.)
Rizzoli R
(2012)
Management of glucocorticoid-induced osteoporosis.
in Calcified tissue international
Tandon N
(2012)
Growth from birth to adulthood and peak bone mass and density data from the New Delhi Birth Cohort.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Lalmohamed A
(2012)
Timing of stroke in patients undergoing total hip replacement and matched controls: a nationwide cohort study.
in Stroke
Litwic A
(2012)
Geographic differences in fractures among women.
in Women's health (London, England)
Culliford DJ
(2012)
The lifetime risk of total hip and knee arthroplasty: results from the UK general practice research database.
in Osteoarthritis and cartilage
Wahl DA
(2012)
A global representation of vitamin D status in healthy populations.
in Archives of osteoporosis
Denison HJ
(2012)
Patterns of dietary supplement use among older men and women in the UK: findings from the Hertfordshire Cohort Study.
in The journal of nutrition, health & aging
Harvey NC
(2012)
Intrauterine growth and postnatal skeletal development: findings from the Southampton Women's Survey.
in Paediatric and perinatal epidemiology
Bazelier MT
(2012)
A simple score for estimating the long-term risk of fracture in patients with multiple sclerosis.
in Neurology
Bazelier MT
(2012)
Use of thiazolidinediones and risk of osteoporotic fracture: disease or drugs?
in Pharmacoepidemiology and drug safety
Cooper C
(2012)
Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial.
in Current medical research and opinion
Pfeilschifter J
(2012)
Regional and age-related variations in the proportions of hip fractures and major fractures among postmenopausal women: the Global Longitudinal Study of Osteoporosis in Women.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Ioannou C
(2012)
The effect of maternal vitamin D concentration on fetal bone.
in The Journal of clinical endocrinology and metabolism
Prieto-Alhambra D
(2012)
Burden of pelvis fracture: a population-based study of incidence, hospitalisation and mortality.
in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
| Title | ASBMR slide kit and videos |
| Description | ASBMR slide kit and videos |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2016 |
| Impact | ASBMR slide kit and videos |
| Title | ASBMR slide kit and videos 2017 |
| Description | ASBMR slide kit and videos 2017 |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2017 |
| Impact | ASBMR slide kit and videos |
| Title | ASBMR webinar (NCH) |
| Description | Webinar on abstract writing |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2018 |
| Impact | Improved abstract writing |
| Title | DXA video UK Biobank |
| Description | DXA video UK Biobank |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2014 |
| Impact | DXA video UK Biobank |
| Title | IOF Webinar (NCH,CC) |
| Description | IOF CTF webinars |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2020 |
| Impact | IOF CTF webinars |
| Title | IOF webinars NHC, CC |
| Description | Webinar on osteoporosis prevention |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2018 |
| Impact | Improved care |
| Title | International Osteoporosis Foundation Slide kit/ videos: WCO |
| Description | Slide kit and video interviews based on science presented at 2015 World Congress in Osteoporosis |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2015 |
| Impact | Widely viewed |
| Title | International Osteoporosis Foundation Video |
| Description | International Osteoporosis Foundation Video |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2014 |
| Impact | International Osteoporosis Foundation Video |
| Title | International Osteoporosis Foundation:Slide kit and videos: ASBMR |
| Description | Production of slide kit and video interviews based on science presented at the 2015 ASBMR scientific meeting. |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2015 |
| Impact | Widely viewed. |
| Title | LifeLab |
| Description | Picture |
| Type Of Art | Image |
| Year Produced | 2014 |
| Impact | LifeLab |
| Title | National Osteoporosis Society Video |
| Description | National Osteoporosis Society Video |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2014 |
| Impact | National Osteoporosis Society Video |
| Title | Osteoarthritis webinar |
| Description | Osteoarthritis webinar |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2014 |
| Impact | Osteoarthritis webinar |
| Title | ROS Osteoporosis Research Roadmap video |
| Description | ROS Osteoporosis Research Roadmap video |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2020 |
| Impact | Increased awareness of osteoporosis |
| Title | WCO slide kit and videos 2016 |
| Description | WCO slide kit and videos 2016 |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2016 |
| Impact | WCO slide kit and videos 2016 |
| Title | WCO slide kit and videos 2017 |
| Description | WCO slide kit and videos 2017 |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2017 |
| Impact | WCO slide kit and videos 2017 |
| Description | ASBMR Professional Practice Committee |
| Geographic Reach | North America |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Provision of bone densitometry with ISCD and IOF. |
| Description | Arthritis Research UK (Fellowships Committee) |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | As a member of the ARUK Clinical Studies Group in Metabolic Bone Disease, I reviewed several large, randomised controlled trials and fellowship applications answering important questions within musculoskeletal medicine. |
| Description | Can we identify patients with high risk of osteoporosis progression who will respond to treatment? |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in other policy documents |
| Impact | Improved management of osteoarthritis |
| Description | Co-authorship of Royal Osteoporosis Society APPG enquiry into FLS (NCH) 2021 |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Commented on NICE Bisphosphonate MTA |
| Geographic Reach | National |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| Description | Contribution of MAVIDOS findings to SACN consultation/ PHE guidance |
| Geographic Reach | National |
| Policy Influence Type | Citation in other policy documents |
| Impact | Improved understanding of the need for vitamin D supplementation at the population level, particularly in winter months. |
| Description | Contribution to SACN vitamin D guidance |
| Geographic Reach | National |
| Policy Influence Type | Citation in other policy documents |
| Description | European guidance on very high fracture risk (NCH, CC) |
| Geographic Reach | Europe |
| Policy Influence Type | Membership of a guideline committee |
| Description | European regulatory guidelines for osteoarthritis |
| Geographic Reach | Europe |
| Policy Influence Type | Citation in other policy documents |
| Impact | Improved management of osteoarthritis |
| Description | FRAX-based intervention thresholds |
| Geographic Reach | National |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| Impact | Improved management of osteoporosis |
| Description | Global Alliance for Musculoskeletal Disease |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| Impact | Global Alliance for Musculoskeletal Disease |
| Description | Guidelines for osteonecrosis of the jaw |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in other policy documents |
| Impact | Improved management of osteoporosis |
| Guideline Title | IOF guidelines for the management of ONJ |
| Description | IOF guidance on ONJ |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in clinical guidelines |
| Impact | IOF guidelines on ONJ |
| Guideline Title | Use of FRAX Risk Assessment System in management of osteoporosis |
| Description | IOF/WHO/ISCD Osteoporosis Guidelines |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in clinical guidelines |
| Impact | Widespread utilisation of FRAX algorithm in North America, Europe, Latin America, Asia, Middle-East and Africa. |
| Description | Lifecourse nutrition for musculoskeletal ageing |
| Geographic Reach | Europe |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| Impact | Improved management of osteoporosis |
| Description | MRC Cohort Strategy |
| Geographic Reach | National |
| Policy Influence Type | Citation in other policy documents |
| Impact | National overview of MRC cohorts. |
| Description | Management of glucocorticoid osteoporosis |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in other policy documents |
| Impact | Improved management of osteoporosis |
| Description | Map of Medicine OP and Vitamin D |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Improved and more efficient treatment of osteoporosis and vitamin D deficiency |
| Description | NOGG revised guidance |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Guidance on assessment and treatment of osteoporosis |
| Guideline Title | National Osteoporosis Guideline Group |
| Description | NOGG; revised thresholds |
| Geographic Reach | National |
| Policy Influence Type | Citation in clinical guidelines |
| Impact | Optimized fracture risk assessment |
| Description | National Osteoporosis Guideline Group Advisory Committee (NCH, CC) |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Improved osteoporosis care |
| Description | National Osteoporosis Guideline Group Advisory Committee (NCH, CC) |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Guideline Title | National Osteoporosis Society Vitamin D Guidelines 2013 |
| Description | National Osteoporosis Society Vitamin D Guidelines 2013 |
| Geographic Reach | National |
| Policy Influence Type | Citation in clinical guidelines |
| Impact | Extensive feedback |
| Description | Participation on NIHR Report "Better Beginnnings" |
| Geographic Reach | National |
| Policy Influence Type | Citation in other policy documents |
| Description | RCOG guidance on Vitamin D in pregnancy |
| Geographic Reach | National |
| Policy Influence Type | Citation in clinical reviews |
| Description | Risk detection for osteoporosis progression |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in other policy documents |
| Impact | Improved management of osteoporosis |
| Description | SACN guidance 2016 |
| Geographic Reach | National |
| Policy Influence Type | Citation in other policy documents |
| Impact | Improved vitamin D guidance |
| Description | Scientific Advisory Committee on Diet and Nutrition- Public Health England Vitamin D Guidance (NCH) |
| Geographic Reach | National |
| Policy Influence Type | Citation in other policy documents |
| Description | Secondary fracture prevention |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in other policy documents |
| Impact | Improved management of osteoporosis |
| Description | The position of strontium in today's management of osteoporosis |
| Geographic Reach | Europe |
| Policy Influence Type | Citation in other policy documents |
| Impact | Improved management of osteoporosis |
| Description | Use of symptomatic slow-acting drugs in knee osteoarthritis |
| Geographic Reach | Europe |
| Policy Influence Type | Citation in other policy documents |
| Impact | Improved management of osteoarthritis |
| Description | WHO European Ministerial Conference 2016 |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| Impact | Report on lifecourse and health |
| Guideline Title | Risk assessment and treatment of osteoporosis |
| Description | WHO Risk Assessment Methodology in UK. |
| Geographic Reach | Asia |
| Policy Influence Type | Citation in clinical guidelines |
| Impact | Widespread utilisation of FRAX algorithm within UK and companion publication (Osteoporosis International; 2011) |
| Description | european osteoporosis guidelines (IOF, ESCEO) CC |
| Geographic Reach | Europe |
| Policy Influence Type | Membership of a guideline committee |
| Impact | Improved osteoporosis care |
| Description | . European Research on Developmental, Birth and Genetic Determinants of Ageing (collaborative project). |
| Amount | £329,977 (GBP) |
| Funding ID | 277849 |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 03/2012 |
| End | 03/2015 |
| Description | ARUK CRF Dr Mark Edwards |
| Amount | £230,000 (GBP) |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2011 |
| End | 09/2014 |
| Description | ARUK Clinical PhD Studentship: Dr Mark Edwards. Understanding the early life and environmental determinants of bone strength and structure using participants from the Hertfordshire Cohort Study. |
| Amount | £240,424 (GBP) |
| Funding ID | 19583 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2011 |
| End | 08/2014 |
| Description | Academic Clinical Fellowship Starter Grant |
| Amount | £10,000 (GBP) |
| Organisation | University of Southampton |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2015 |
| End | 12/2016 |
| Description | Arthritis Research UK Centre of Excellence for Sport and Exercise Injuries |
| Amount | £76,000 (GBP) |
| Organisation | Versus Arthritis |
| Department | Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2013 |
| End | 09/2018 |
| Description | Arthritis Research UK Centre of Excellence for Sport and Exercise Injuries |
| Amount | £2,500,000 (GBP) |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2013 |
| End | 03/2018 |
| Description | Arthritis Research UK Centre of Excellence in Epidemiology |
| Amount | £120,410 (GBP) |
| Funding ID | 20380 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2013 |
| End | 09/2018 |
| Description | Arthritis Research UK Centre of Excellence in Epidemiology |
| Amount | £2,402,000 (GBP) |
| Funding ID | 20380 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2013 |
| End | 12/2018 |
| Description | Arthritis Research UK Clinical Studies Grant |
| Amount | £362,894 (GBP) |
| Funding ID | 21231 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2016 |
| End | 09/2021 |
| Description | BHF Research Training Fellowship |
| Amount | £231,716 (GBP) |
| Funding ID | FS/17/81/33318 |
| Organisation | British Heart Foundation (BHF) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2018 |
| End | 10/2021 |
| Description | Biomedical Research Centre Nutrition - Respiratory Research with Prof R Read et al |
| Amount | £15,000,000 (GBP) |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Clinical Research Training Fellowship |
| Amount | £252,397 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2016 |
| End | 08/2019 |
| Description | Cohort Resources Facility |
| Amount | £1,000,000 (GBP) |
| Organisation | Economic and Social Research Council |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2012 |
| End | 04/2017 |
| Description | Collaborative Project Grant: National Clinical Audit of Rheumatoid & Early Inflammatory Arthritis. Collaborative project with BSR and Northgate. |
| Amount | £172,500 (GBP) |
| Organisation | The Health Quality Improvement Partnership (HQIP) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2013 |
| End | 01/2016 |
| Description | Data Management Planning for Secure Services (DMP-SS) |
| Amount | £99,904 (GBP) |
| Organisation | Jisc |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2011 |
| End | 12/2012 |
| Description | Describing habitual levels of physical activity (PA) in older people in terms of impact loads and how this relates to bone and other symptoms (VIBE) |
| Amount | £184,576 (GBP) |
| Funding ID | MR/K024973/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 12/2013 |
| End | 11/2016 |
| Description | Developmental origins of child neurodevelopment: Novel approaches to clinical risk prediction using an international metadataset. |
| Amount | £364,324 (GBP) |
| Funding ID | MR/V029169/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2021 |
| End | 10/2027 |
| Description | Does maternal gestational vitamin D supplementation influence offspring DNA methylation in childhood? |
| Amount | £29,984 (GBP) |
| Funding ID | SGL023\1072 |
| Organisation | Academy of Medical Sciences (AMS) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2020 |
| End | 12/2021 |
| Description | EPOSA |
| Amount | £225,057 (GBP) |
| Organisation | Porticus |
| Sector | Charity/Non Profit |
| Country | Global |
| Start | 12/2013 |
| End | 11/2016 |
| Description | EPSRC Project Grant: Handheld microindentation - a direct assessment of bone fracture risk? |
| Amount | £475,000 (GBP) |
| Funding ID | EP/J008192/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2012 |
| End | 04/2015 |
| Description | ERA HDHL |
| Amount | £1,200,000 (GBP) |
| Funding ID | BB/P028179/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 02/2020 |
| Description | EU Collaborative Project: Food based solutions for Optimal vitamin D Nutrition and health through the life cycle (ODIN) |
| Amount | € 5,980,000 (EUR) |
| Funding ID | 613977 |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 11/2013 |
| End | 10/2017 |
| Description | Epigenetic biomarkers and determinants of cardiovascular risk in children (With Prof M Hanson et al) |
| Amount | £1,400,000 (GBP) |
| Funding ID | RG/15/17/31749 |
| Organisation | British Heart Foundation (BHF) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 03/2020 |
| Description | Epigenetic mechanisms linking maternal pre-conceptional micronutrient supplementation with offspring health in India and The Gambia |
| Amount | £486,087 (GBP) |
| Funding ID | MR/N006208/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2015 |
| End | 04/2018 |
| Description | HTA Project Grant: Risks and benefits of bisphosphonate use in patients with chronic kidney disease |
| Amount | £340,485 (GBP) |
| Funding ID | HTA/14/36/02 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2015 |
| End | 05/2017 |
| Description | Health risks and benefits of extended working life (the HEAF study) |
| Amount | £841,392 (GBP) |
| Funding ID | ES/L002663/1 |
| Organisation | University of Southampton |
| Department | ESRC National Centre for Research Methods |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2013 |
| End | 02/2018 |
| Description | IOF-Servier Young Investigator Research Grant |
| Amount | € 40,000 (EUR) |
| Organisation | Servier Laboratories |
| Sector | Private |
| Country | France |
| Start | 01/2012 |
| End | 12/2013 |
| Description | Joint IALSA/HALCyon Program Project: Integrative analysis of longitudinal studies of aging |
| Amount | $7,700,000 (USD) |
| Funding ID | 5P01AG043362-05 |
| Organisation | National Institutes of Health (NIH) |
| Department | National Institute on Aging |
| Sector | Public |
| Country | United States |
| Start | 03/2013 |
| End | 02/2018 |
| Description | MRC Capital Award |
| Amount | £134,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 03/2019 |
| Description | MRC Capital Funding |
| Amount | £288,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| Description | MRC Capital Funding |
| Amount | £310,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 03/2018 |
| Description | MRC Capital Prioritisation Award |
| Amount | £134,000 (GBP) |
| Organisation | University of Southampton |
| Department | MRC Lifecourse Epidemiology Unit |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 03/2019 |
| End | 03/2022 |
| Description | MRC Capital award 2020 2021 Scanco XtremeCT2 |
| Amount | £325,000 (GBP) |
| Funding ID | 4050776844 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2020 |
| End | 03/2023 |
| Description | MRC Capital/infrastructure (including equipment |
| Amount | £60,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2013 |
| End | 12/2014 |
| Description | MRC Centenary Award |
| Amount | £45,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2012 |
| End | 12/2013 |
| Description | MRC LEU Extension |
| Amount | £1,500,000 (GBP) |
| Funding ID | MRC LEU |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2020 |
| End | 10/2020 |
| Description | MRC LEU Extension |
| Amount | £1,800,000 (GBP) |
| Funding ID | MRC LEU |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2020 |
| End | 06/2021 |
| Description | MRC Lifecourse Epidemiology Centre - Core Support |
| Amount | £1,483,000 (GBP) |
| Funding ID | MC_PC_21000 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2021 |
| End | 03/2026 |
| Description | MRC Lifecourse Epidemiology Unit (and linked programme grants) |
| Amount | £14,400,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 03/2020 |
| Description | MRC National Musculoskeletal Network |
| Amount | £150,847 (GBP) |
| Funding ID | MC_PC_21022 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2022 |
| End | 02/2024 |
| Description | MRC UUP Capital Award |
| Amount | £288,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 03/2015 |
| Description | Manualising Individual Placements Support for people with unemployment due to chronic pain and testing the feasibility of a randomised controlled trial. |
| Amount | £317,300 (GBP) |
| Funding ID | 15/108 |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2017 |
| End | 03/2019 |
| Description | Maths, Engineering & Life Sciences: making connections for precision medicine (with Prof Deborah Mackay et al) |
| Amount | £500,000 (GBP) |
| Funding ID | MC_PC_15078 |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Human Nutrition Research Group |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 02/2018 |
| Description | Maths, Engineering and Life Sciences: making connections for precision medicine |
| Amount | £500,000 (GBP) |
| Funding ID | MC_PC_15078 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 02/2018 |
| Description | Mid-Career Equipment Grant: Dr Kumaran Kalyanaraman |
| Amount | £60,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2013 |
| End | 12/2014 |
| Description | NIHR |
| Amount | £43,129 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2010 |
| End | 07/2012 |
| Description | NIHR Biomedical Research Centre in Nutrition |
| Amount | £9,600,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2012 |
| End | 03/2017 |
| Description | NIHR Biomedical Research Unit: Musculoskeletal Disease |
| Amount | £6,000,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2012 |
| End | 02/2019 |
| Description | NIHR HTA |
| Amount | £317,327 (GBP) |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2017 |
| End | 09/2020 |
| Description | NIHR HTA Grant |
| Amount | £340,485 (GBP) |
| Organisation | National Institute for Health Research |
| Department | NIHR Clinical Research Network (CRN) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 05/2015 |
| End | 05/2017 |
| Description | NIHR PGfAR |
| Amount | £2,166,779 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2017 |
| End | 09/2022 |
| Description | NIHR SBRC Nutrition |
| Amount | £9,000,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2012 |
| End | 03/2019 |
| Description | NIHR Senior Investigator Award |
| Amount | £75,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2014 |
| End | 09/2017 |
| Description | NOS Project Grant CPRD |
| Amount | £79,905 (GBP) |
| Organisation | Royal Osteoporosis Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2014 |
| End | 12/2016 |
| Description | Nutritional determinants of skeletal development and bone loss: an investigation using a novel computer vision assessment of bone microarchitecture |
| Amount | £36,000 (GBP) |
| Organisation | University of Southampton |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 08/2022 |
| End | 09/2025 |
| Description | PhD fellowship |
| Amount | £33,000 (GBP) |
| Organisation | The Gerald Kerkut Charitable Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2010 |
| End | 02/2013 |
| Description | Preventing broken bones in older people: from research to policy to practice |
| Amount | £29,566 (GBP) |
| Funding ID | MRF-145-0011-DG-HARV-C0913 |
| Organisation | Medical Research Council (MRC) |
| Department | Medical Research Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2022 |
| End | 09/2022 |
| Description | Programme 1: Musculoskeletal health in later life |
| Amount | £3,347,000 (GBP) |
| Funding ID | MC_PC_21001 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2021 |
| End | 03/2026 |
| Description | Programme 3: Early development and risk of adult musculoskeletal disease |
| Amount | £1,809,000 (GBP) |
| Funding ID | MC_PC_21003 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2021 |
| End | 03/2026 |
| Description | Project Grant - The Role of hospital organisation, surgical factors, and the enhanced recovery pathway, on patient outcomes and NHS costs following primary hip and knee replacement surgery: spacial and longitudinal analysis of routine data |
| Amount | £510,503 (GBP) |
| Funding ID | 14/46/02 |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 03/2018 |
| Description | Project Grant: Dr Christopher Holroyd. How do pre- and post-natal environmental factors and parental bone mass influence offspring bone size and density |
| Amount | £85,000 (GBP) |
| Organisation | Southampton Rheumatology Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2011 |
| End | 09/2013 |
| Description | Project Grant: Musculoskeletal health and extended working life |
| Amount | £180,014 (GBP) |
| Funding ID | 19817 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2012 |
| End | 09/2014 |
| Description | Project grant |
| Amount | £328,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2017 |
| End | 09/2020 |
| Description | Project grant: Epigenetic biomarkers and determinants of cardiovascular risk in children |
| Amount | £1,400,000 (GBP) |
| Funding ID | RG/15/17/31749 |
| Organisation | British Heart Foundation (BHF) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 03/2020 |
| Description | Research Project Grant: Describing habitual levels of physcial activity (PA) in older people in terms of impact loads and how this relates to bone and other symptoms. |
| Amount | £184,576 (GBP) |
| Funding ID | MR/K024973/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2013 |
| End | 12/2016 |
| Description | UK Biobank Imaging |
| Amount | £9,600,000 (GBP) |
| Funding ID | MC_PC_12027 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2014 |
| End | 12/2015 |
| Description | UK Biobank Imaging Full Funding |
| Amount | £32,000,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 04/2022 |
| Description | UK Centre of Excellence for Musculoskeletal Health and Work |
| Amount | £1,400,000 (GBP) |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2014 |
| End | 11/2019 |
| Description | UKRI WCL Capital funding 2020 2021 DXA and MSK Scanning Suite |
| Amount | £216,857 (GBP) |
| Funding ID | 4050801857 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2020 |
| End | 03/2021 |
| Description | University Unit Capital Equipment Award |
| Amount | £118,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2013 |
| End | 12/2014 |
| Description | University Unit Partnership Grants: Epigenetic processes and the developmental origins of health and disease |
| Amount | £841,392 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2013 |
| End | 08/2018 |
| Description | Wellcome Trust Collaborative Award |
| Amount | £1,600,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2018 |
| End | 09/2023 |
| Title | Batman |
| Description | Bayesian analysis of epigenome-wide methylation |
| Type Of Material | Physiological assessment or outcome measure |
| Year Produced | 2014 |
| Provided To Others? | Yes |
| Impact | Bayesian analysis of epigenome-wide methylation |
| Title | Epidemiology of Sporting Injuries |
| Description | Sporting injury database for elite championship professional soccer club. |
| Type Of Material | Biological samples |
| Provided To Others? | No |
| Impact | Decline in serious injury incidence; promotion to premiership expected. |
| Title | Health Conversation Skills |
| Description | Peer-led behaviour change intervention package |
| Type Of Material | Physiological assessment or outcome measure |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | New Zealand, South Africa, India, Australia Modification of dietary pattern and reduction of adiposity |
| Title | Healthy conversation skills |
| Description | Peer-led behavioural package to enhance optimal nutritional choices among young women of childbearing age. |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2011 |
| Provided To Others? | Yes |
| Impact | Worldwide utilisation of behaviour change package. |
| Title | Hertfordshire Cohort Study |
| Description | Cohort Study |
| Type Of Material | Biological samples |
| Year Produced | 2006 |
| Provided To Others? | Yes |
| Impact | Papers |
| Title | Hertfordshire Cohort Study |
| Description | Range of phenotypic data, DNA and posterity blood samples. |
| Type Of Material | Biological samples |
| Year Produced | 2006 |
| Provided To Others? | Yes |
| Impact | Numerous publications (see list for details). |
| Title | High resolution peripheral quantitative computed tomography |
| Description | Obtains virtual bone biopsy |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2014 |
| Provided To Others? | Yes |
| Impact | Obtains virtual bone biopsy |
| Title | Hipmorph |
| Description | Automated assessment of hip OA |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2014 |
| Provided To Others? | Yes |
| Impact | Automated assessment of hip OA |
| Title | Kneemorph |
| Description | Automated system for evaluation of radiographic knee OA. |
| Type Of Material | Improvements to research infrastructure |
| Provided To Others? | No |
| Impact | Reproducible severity grading of osteoarthritis. |
| Title | Novel seasonal adjustment for vitamin D concentrations |
| Description | Novel method for adjusting the vitamin D concentrations for season, independent of assays used. |
| Type Of Material | Model of mechanisms or symptoms - human |
| Provided To Others? | No |
| Impact | Tracking of 25-hydroxyvitamin D status during pregnancy: the importance of vitamin D supplementation. Moon RJ, Crozier SR, Dennison EM, Davies JH, Robinson SM, Inskip HM, Godfrey KM, Cooper C, Harvey NC. Am J Clin Nutr. 2015 Nov;102(5):1081-7. doi: 10.3945/ajcn.115.115295. |
| Title | SWS Data and samples |
| Description | Large collection of data and samples from women and children in the Southampton Women's Survey |
| Type Of Material | Biological samples |
| Year Produced | 2006 |
| Provided To Others? | Yes |
| Impact | All the SWS publications. Further grant funding for research within the SWS and for interventions arising out of it. |
| Title | Complex multi source datasets |
| Description | Complex multi source datasets |
| Type Of Material | Data analysis technique |
| Provided To Others? | No |
| Impact | Complex multi source datasets |
| Title | Epigenetic microarray data distribution |
| Description | Epigenetic microarray data distribution |
| Type Of Material | Data analysis technique |
| Provided To Others? | No |
| Impact | Epigenetic microarray data distribution |
| Title | EuroHealth Ageing |
| Description | EuroHealth Ageing |
| Type Of Material | Database/Collection of data |
| Year Produced | 2014 |
| Provided To Others? | Yes |
| Impact | Mechanisms of ageing |
| Title | Fourier adjusted calcidiol |
| Description | Novel approach to adjustment of 25(OH)D for season, allowing combination of differing assays |
| Type Of Material | Data analysis technique |
| Provided To Others? | No |
| Impact | Published manuscript |
| Title | Growth modelling |
| Description | Growth modelling |
| Type Of Material | Data analysis technique |
| Provided To Others? | No |
| Impact | Growth modelling |
| Title | Hierarchical Data Modelling |
| Description | Hierarchical Data Modelling |
| Type Of Material | Data analysis technique |
| Provided To Others? | No |
| Impact | Hierarchical Data Modelling |
| Title | NIH VDSOP |
| Description | Participation, through ODIN, in NIH vitamin D standardisation procedures. |
| Type Of Material | Data handling & control |
| Provided To Others? | No |
| Impact | Ongoing |
| Title | SPRING Trial |
| Description | SPRING Trial |
| Type Of Material | Database/Collection of data |
| Year Produced | 2021 |
| Provided To Others? | No |
| Impact | SPRING Trial |
| Description | ALPHABET |
| Organisation | Erasmus University Rotterdam |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | National Institute of Health and Medical Research (INSERM) |
| Department | Center for Epidemiological and Bio Statistics Research at Sorbonne |
| Country | France |
| Sector | Public |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | University College Dublin |
| Department | School of Physics |
| Country | Ireland |
| Sector | Academic/University |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | University College Dublin |
| Country | Ireland |
| Sector | Academic/University |
| PI Contribution | WP5, bone outcomes |
| Collaborator Contribution | Consortium |
| Impact | Ongoing |
| Start Year | 2017 |
| Description | ALPHABET |
| Organisation | University of Bristol |
| Department | Biomedical Research Unit in Nutrition, Diet and Lifestyle |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALPHABET |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | WP5, bone outcomes |
| Collaborator Contribution | Consortium |
| Impact | Ongoing |
| Start Year | 2017 |
| Description | ALPHABET |
| Organisation | University of South Carolina |
| Department | Arnold School of Public Health |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Epigenetic determinants of bone development |
| Collaborator Contribution | Epigenetic determinants of body composition and cognition |
| Impact | N/A |
| Start Year | 2016 |
| Description | ALSPAC placenta |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Placental determinants of bone mass |
| Collaborator Contribution | Placental determinants of bone mass |
| Impact | Ongoing |
| Start Year | 2013 |
| Description | ARUK MAVIDOS collaboration |
| Organisation | University College Cork |
| Country | Ireland |
| Sector | Academic/University |
| PI Contribution | Scientific collaboration |
| Collaborator Contribution | Scientific collaboration |
| Impact | 3 papers |
| Start Year | 2013 |
| Description | ARUK MAVIDOS collaboration |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | DXA Lead |
| Collaborator Contribution | Other imaging |
| Impact | 1 paper |
| Start Year | 2014 |
| Description | ARUK/MRC Centre of Excellence in Work and Musculoskeletal Disorders |
| Organisation | University of Liverpool |
| Department | School of Medicine Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research collaboration |
| Collaborator Contribution | Research collaboration |
| Impact | PhD students |
| Start Year | 2015 |
| Description | ARUK/MRC Centre of Excellence in Work and Musculoskeletal Health |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research collaboration |
| Collaborator Contribution | Research collaboration |
| Impact | PhD students |
| Start Year | 2015 |
| Description | ARUK/MRC Centre of Excellence in Work and Musculoskeletal Health |
| Organisation | University of Oxford |
| Department | School of Medicine |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research collaboration |
| Collaborator Contribution | Research collaboration |
| Impact | PhD students |
| Start Year | 2015 |
| Description | AUGMENT UK Biobank collaboration |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | AUGMENT UK Biobank collaboration |
| Collaborator Contribution | AUGMENT UK Biobank collaboration |
| Impact | AUGMENT UK Biobank collaboration |
| Start Year | 2017 |
| Description | AUGMENT UK Biobank collaboration |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | AUGMENT UK Biobank collaboration |
| Collaborator Contribution | AUGMENT UK Biobank collaboration |
| Impact | AUGMENT UK Biobank collaboration |
| Start Year | 2017 |
| Description | CPRD |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | UK Osteoporosis Epidemiology |
| Collaborator Contribution | UK Osteoporosis Epidemiology |
| Impact | UK Osteoporosis Epidemiology |
| Start Year | 2014 |
| Description | Danish Population Registry |
| Organisation | University of Southern Denmark |
| Country | Denmark |
| Sector | Academic/University |
| PI Contribution | Scientific collaboration |
| Collaborator Contribution | Scientific collaboration |
| Impact | 2 papers |
| Start Year | 2013 |
| Description | Danish Population Registry |
| Organisation | University of Southern Denmark |
| Country | Denmark |
| Sector | Academic/University |
| PI Contribution | Scientific collaboration |
| Collaborator Contribution | Scientific collaboration |
| Impact | 2 papers |
| Start Year | 2013 |
| Description | Department of Public Health, Cambridge |
| Organisation | University of Cambridge |
| Department | Department of Public Health and Primary Care |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Colaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2008 |
| Description | Dr Alireza Moayyeri |
| Organisation | University of Cambridge |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2009 |
| Description | Dr Ann Prentice |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Human Nutrition Research Group |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2009 |
| Description | Dr Barbara Boucher |
| Organisation | Queen Mary University of London |
| Department | Barts and The London School of Medicine and Dentistry |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2008 |
| Description | Dr Brent Richards |
| Organisation | McGill University |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2008 |
| Description | Dr Francis Finucane |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research collaboration |
| Collaborator Contribution | Research collaboration |
| Impact | Clinical impact |
| Start Year | 2009 |
| Description | Dr Geeta Mishra |
| Organisation | University College London |
| Department | MRC Unit for Lifelong Health and Ageing |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2007 |
| Description | Dr Jonathan Reeve |
| Organisation | University of Cambridge |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2006 |
| Description | Dr Ken Ong |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical impact |
| Start Year | 2008 |
| Description | Dr Natascha van Schoor |
| Organisation | University of Amsterdam |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2008 |
| Description | Dr Rebecca Hardy |
| Organisation | University College London |
| Department | MRC Unit for Lifelong Health and Ageing |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2006 |
| Description | Dr Ruth Loos |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research collaboration |
| Collaborator Contribution | Research collaboration |
| Impact | Clinical impact |
| Start Year | 2007 |
| Description | EPOSA |
| Organisation | Free University of Amsterdam |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Collaborative science. |
| Collaborator Contribution | Collaborative science. |
| Impact | 5 papers |
| Start Year | 2013 |
| Description | EU EarlyNutrition |
| Organisation | Ludwig Maximilian University of Munich (LMU Munich) |
| Department | University Clinic of Munich |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Work package leadership |
| Collaborator Contribution | Overall collaboration management |
| Impact | 1: Moon RJ, Crozier SR, Dennison EM, Davies JH, Robinson SM, Inskip HM, Godfrey KM, Cooper C, Harvey NC. Tracking of 25-hydroxyvitamin D status during pregnancy: the importance of vitamin D supplementation. Am J Clin Nutr. 2015 Nov;102(5):1081-7. doi: 10.3945/ajcn.115.115295. Epub 2015 Sep 23. PubMed PMID: 26399867; PubMed Central PMCID: PMC4634223. 2: Vogel C, Parsons C, Godfrey K, Robinson S, Harvey NC, Inskip H, Cooper C, Baird J. Greater access to fast-food outlets is associated with poorer bone health in young children. Osteoporos Int. 2015 Oct 12. [Epub ahead of print] PubMed PMID: 26458387. 3: Moon RJ, Harvey NC, Cooper C. ENDOCRINOLOGY IN PREGNANCY: Influence of maternal vitamin D status on obstetric outcomes and the fetal skeleton. Eur J Endocrinol. 2015 Aug;173(2):R69-83. doi: 10.1530/EJE-14-0826. Epub 2015 Apr 10. Review. PubMed PMID: 25862787. 4: Cleal JK, Day PE, Simner CL, Barton SJ, Mahon PA, Inskip HM, Godfrey KM, Hanson MA, Cooper C, Lewis RM, Harvey NC; SWS Study Group. Placental amino acid transport may be regulated by maternal vitamin D and vitamin D-binding protein: results from the Southampton Women's Survey. Br J Nutr. 2015 Jun 28;113(12):1903-10. doi: 10.1017/S0007114515001178. Epub 2015 May 5. PubMed PMID: 25940599; PubMed Central PMCID: PMC4498463. 5: Moon RJ, Cole ZA, Crozier SR, Curtis EM, Davies JH, Gregson CL, Robinson SM, Dennison EM, Godfrey KM, Inskip HM, Cooper C, Harvey NC; Southampton Women's Survey Study Group. Longitudinal changes in lean mass predict pQCT measures of tibial geometry and mineralisation at 6-7 years. Bone. 2015 Jun;75:105-10. doi: 10.1016/j.bone.2015.02.015. Epub 2015 Feb 20. PubMed PMID: 25703480; PubMed Central PMCID: PMC4556067. 6: Moon RJ, Harvey NC, Davies JH, Cooper C. Vitamin D and bone development. Osteoporos Int. 2015 Apr;26(4):1449-51. doi: 10.1007/s00198-014-2976-y. Epub 2014 Dec 2. PubMed PMID: 25448839. 7: Robinson SM, Crozier SR, Harvey NC, Barton BD, Law CM, Godfrey KM, Cooper C, Inskip HM. Modifiable early-life risk factors for childhood adiposity and overweight: an analysis of their combined impact and potential for prevention. Am J Clin Nutr. 2015 Feb;101(2):368-75. doi: 10.3945/ajcn.114.094268. Epub 2014 Dec 3. PubMed PMID: 25646335; PubMed Central PMCID: PMC4307207. 8: Moon RJ, Harvey NC, Davies JH, Cooper C. Vitamin D and skeletal health in infancy and childhood. Osteoporos Int. 2014 Dec;25(12):2673-84. doi: 10.1007/s00198-014-2783-5. Epub 2014 Aug 20. PubMed PMID: 25138259; PubMed Central PMCID: PMC4224585. 9: Harvey N, Dennison E, Cooper C. Osteoporosis: a lifecourse approach. J Bone Miner Res. 2014 Sep;29(9):1917-25. doi: 10.1002/jbmr.2286. Review. PubMed PMID: 24861883. 10: Harvey NC, Holroyd C, Ntani G, Javaid K, Cooper P, Moon R, Cole Z, Tinati T, Godfrey K, Dennison E, Bishop NJ, Baird J, Cooper C. Vitamin D supplementation in pregnancy: a systematic review. Health Technol Assess. 2014 Jul;18(45):1-190. doi: 10.3310/hta18450. Review. PubMed PMID: 25025896; PubMed Central PMCID: PMC4124722. 11: Curtis EM, Moon RJ, Dennison EM, Harvey NC. Prenatal calcium and vitamin D intake, and bone mass in later life. Curr Osteoporos Rep. 2014 Jun;12(2):194-204. doi: 10.1007/s11914-014-0210-7. Review. PubMed PMID: 24740166. 12: de Jongh RT, Crozier SR, D'Angelo S, Pike KC, Roberts G, Lucas JS, Inskip H, Godfrey KM, Cooper C, Harvey NC; Southampton Women's Survey Study Group. Maternal 25-hydroxyvitamin D levels in relation to offspring respiratory symptoms and infections. Eur Respir J. 2014 Apr;43(4):1181-3. doi: 10.1183/09031936.00116913. Epub 2013 Dec 12. PubMed PMID: 24337044; PubMed Central PMCID: PMC3973533. 13: Harvey NC, Cooper C. Vitamin D status and ill health. Lancet Diabetes Endocrinol. 2014 Apr;2(4):e9. doi: 10.1016/S2213-8587(14)70045-2. PubMed PMID: 24703059. |
| Start Year | 2012 |
| Description | EULAR Centre of Excellence in Rheumatology |
| Organisation | University Hospital Southampton NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Enhanced collaboration |
| Collaborator Contribution | Enhanced collaboration |
| Impact | Various publications. |
| Start Year | 2010 |
| Description | Epidemiology Maastricht |
| Organisation | Maastricht University (UM) |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Epidemiology of fractures in UK |
| Collaborator Contribution | Epidemiology of fractures in UK |
| Impact | Ongoing |
| Start Year | 2014 |
| Description | Epidemiology Utrecht |
| Organisation | Utrecht University |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Epidemiology of fractures in UK |
| Collaborator Contribution | Epidemiology, medication use, mortality |
| Impact | Ongoing |
| Start Year | 2014 |
| Description | Epigenetic Studies |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Description | Fracture Risk Assessment |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Fracture Risk Assessment |
| Collaborator Contribution | Fracture Risk Assessment |
| Impact | Fracture Risk Assessment |
| Start Year | 2014 |
| Description | GEFOS |
| Organisation | Genetic Factors for Osteoporosis Consortium (GEFOS) |
| Country | Netherlands |
| Sector | Charity/Non Profit |
| PI Contribution | Samples |
| Collaborator Contribution | Genetic analysis |
| Impact | ongoing |
| Start Year | 2010 |
| Description | GIANT and MAGIC Consortia |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Description | GPRD Studies |
| Organisation | Utrecht University |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Description | Genetic Epidemiology of type 2 diabetes mellitus |
| Organisation | University of Cambridge |
| Department | Department of Clinical Biochemistry |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Contribution of anonymised phenotypic data; statistical expertise |
| Impact | Publication. PubMed ID: 17019603 |
| Start Year | 2006 |
| Description | HALCYON |
| Organisation | University College London |
| Department | MRC Unit for Lifelong Health and Ageing |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Provision of data from Hertfordshire Cohort Study |
| Collaborator Contribution | Multiple publications on sarcopenia and physical frailty. |
| Impact | 3 publications |
| Start Year | 2010 |
| Description | HR pQCT |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Inflammatory disease, bone erosion |
| Collaborator Contribution | Inflammatory disease, bone erosion |
| Impact | Inflammatory disease, bone erosion |
| Start Year | 2014 |
| Description | Helsinki Cohort Study |
| Organisation | University of Helsinki |
| Country | Finland |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Description | Hertfordshire Cohort Study |
| Organisation | Johns Hopkins University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Research |
| Collaborator Contribution | ResearchResearchResearchResearchResearchResearchResearchResearch |
| Impact | Research |
| Description | Hertfordshire Cohort Study |
| Organisation | University College London |
| Department | MRC Unit for Lifelong Health and Ageing |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Collaborator Contribution | ResearchResearchResearchResearchResearchResearchResearchResearch |
| Impact | Research |
| Description | Hertfordshire Cohort Study |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Collaborator Contribution | ResearchResearchResearchResearchResearchResearchResearchResearch |
| Impact | Research |
| Description | Hertfordshire Cohort Study |
| Organisation | University of Amsterdam |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Research |
| Collaborator Contribution | ResearchResearchResearchResearchResearchResearchResearchResearch |
| Impact | Research |
| Description | Hertfordshire Cohort Study |
| Organisation | University of Birmingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Collaborator Contribution | ResearchResearchResearchResearchResearchResearchResearchResearch |
| Impact | Research |
| Description | Hertfordshire Cohort Study |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Collaborator Contribution | ResearchResearchResearchResearchResearchResearchResearchResearch |
| Impact | Research |
| Description | Hertfordshire Cohort Study |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Collaborator Contribution | ResearchResearchResearchResearchResearchResearchResearchResearch |
| Impact | Research |
| Description | Hertfordshire Cohort Study |
| Organisation | University of Cambridge |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Collaborator Contribution | ResearchResearchResearchResearchResearchResearchResearchResearch |
| Impact | Research |
| Description | Hertfordshire Physical Activity Intervention Trial (HPAT) |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Contribution of anonymised phenotypic data |
| Impact | Publications. Pubmed ID: 19545359 |
| Start Year | 2006 |
| Description | IOF Barcelona |
| Organisation | Autonomous University of Barcelona (UAB) |
| Country | Spain |
| Sector | Academic/University |
| PI Contribution | Scientific collaboration |
| Collaborator Contribution | Scientific collaboration |
| Impact | 3 papers |
| Start Year | 2014 |
| Description | IOF vitamin D |
| Organisation | University of Florence |
| Department | Department of Internal Medicine |
| Country | Italy |
| Sector | Academic/University |
| PI Contribution | Epidemiological data |
| Collaborator Contribution | Epidemiological data |
| Impact | Rizzoli R et al. CMRO 2013;29:1-9. |
| Start Year | 2011 |
| Description | IOF vitamin D |
| Organisation | University of Geneva |
| Department | Division of Bone Diseases |
| Country | Switzerland |
| Sector | Academic/University |
| PI Contribution | Vitamin D guidelines |
| Collaborator Contribution | Epidemiological data |
| Impact | Paper: Rizzoli et al, CMRO 2013;29:1-9. |
| Start Year | 2012 |
| Description | IOF vitamin D |
| Organisation | University of Leuven |
| Department | Centre for Metabolic Bone Diseases |
| Country | Belgium |
| Sector | Academic/University |
| PI Contribution | Epidemiological data |
| Collaborator Contribution | Epidemiological data |
| Impact | Rizzoli R et al. CMRO 2013;29:1-9. |
| Start Year | 2011 |
| Description | Improving pregnancy outcome in obese women |
| Organisation | Guy's and St Thomas' NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Intellectual input in design of study and development of protocol. On-going involvement in monitoring the study progress |
| Collaborator Contribution | Collaboration with a well-respected group |
| Impact | NIHR grant funding |
| Start Year | 2008 |
| Description | LPIN1 genotype and diet |
| Organisation | The Wellcome Trust Sanger Institute |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Contribution of anonymised phenotypic data |
| Impact | Publications. Pubmed ID: 18591397 |
| Start Year | 2007 |
| Description | LPIN1 genotype and diet |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Contribution of anonymised phenotypic data |
| Impact | Publications. Pubmed ID: 18591397 |
| Start Year | 2007 |
| Description | LifeLab Southampton |
| Organisation | University of Southampton |
| Department | School of Medicine Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Our research findings have shown the importance of diet and lifestyle before children are even conceived, so we need to engage with children at schools to enable them to understand the importance of their behaviours now on their long-term health and that of their children |
| Collaborator Contribution | Enabled us to contribute more effectively to public engagement in science by getting our research findings communicated to teenagers in and around Southampton |
| Impact | Many public engagement activities with teenagers, with anecdotal marked improvement in the behaviour of some. Paper in preparation showing shifts in knowledge from before to after participating in the LifeLab activities. |
| Start Year | 2007 |
| Description | Lifecourse influences on women's smoking patterns |
| Organisation | Lancaster University |
| Department | Institute for Health Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Data provision, coding and cleaning, grant and paper writing |
| Collaborator Contribution | Data analysis, paper writing, grant writing |
| Impact | 17708005, 16962221, 16476753 |
| Description | Lung function in 6 year old children |
| Organisation | University of Southampton |
| Department | School of Medicine Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Data collection, grant and paper writing |
| Collaborator Contribution | Grant and paper writing. Data collection, analysis of samples |
| Impact | Papers now submitted |
| Start Year | 2007 |
| Description | MAVIDOS |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Human Nutrition Research Group |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Start Year | 2006 |
| Description | MAVIDOS |
| Organisation | Medical Research Council (MRC) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Scientific collaboration |
| Collaborator Contribution | Scientific collaboration |
| Impact | 2 abstracts |
| Start Year | 2013 |
| Description | MAVIDOS |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Start Year | 2006 |
| Description | MAVIDOS |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Start Year | 2006 |
| Description | MAVIDOS Childhood Follow up |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Recruitment to MAVIDOS 6 year follow-up in Sheffield |
| Collaborator Contribution | Recruitment to MAVIDOS six-year follow-up in Sheffield |
| Impact | N/A |
| Start Year | 2016 |
| Description | MAVIDOS Childhood Follow-up Oxford |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Recruitment of children to MAVIDOS six-year follow-up in Oxford |
| Collaborator Contribution | Recruitment of children to MAVIDOS six-year follow-up in Oxford |
| Impact | N/A |
| Start Year | 2016 |
| Description | MAVIDOS Oxford CVD |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Vitamin D in pregnancy and offspring cardiac structure and function |
| Collaborator Contribution | Vitamin D in pregnancy and offspring cardiac structure and function |
| Impact | Ongoing |
| Start Year | 2015 |
| Description | MRC Epidemiology Unit (EU), University of Cambridge |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2006 |
| Description | MRC LLHA University College London |
| Organisation | University College London |
| Department | MRC Unit for Lifelong Health and Ageing |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2009 |
| Description | MRC SCOOP Trial |
| Organisation | University of Birmingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Start Year | 2006 |
| Description | MRC SCOOP Trial |
| Organisation | University of East Anglia |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Start Year | 2006 |
| Description | MRC SCOOP Trial |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Start Year | 2006 |
| Description | MRC SCOOP Trial |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Start Year | 2006 |
| Description | MRC SCOOP Trial |
| Organisation | University of York |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Start Year | 2006 |
| Description | Metabolic syndrome in HCS |
| Organisation | GlaxoSmithKline (GSK) |
| Country | Global |
| Sector | Private |
| PI Contribution | Contribution of anonymised phenotypic data; statistical expertise |
| Impact | Multiple abstracts in this field |
| Description | Nigel Loveridge |
| Organisation | University of Cambridge |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2006 |
| Description | Nutrition BRU |
| Organisation | University of Southampton |
| Department | Faculty of Health Sciences |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Preparation of application, administration and conduct of some of the core projects |
| Collaborator Contribution | Allowed us to conduct complementary studies arising out of the Southampton Women's Survey |
| Impact | Grant funding |
| Start Year | 2008 |
| Description | ODIN |
| Organisation | University College Cork |
| Country | Ireland |
| Sector | Academic/University |
| PI Contribution | Scientific collaboration |
| Collaborator Contribution | Scientific collaboration |
| Impact | 3 papers |
| Start Year | 2013 |
| Description | Osteoarthritis Programme |
| Organisation | Imperial College London |
| Department | Department of Epidemiology and Biostatistics |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Collaborator Contribution | Novel technique for grading osteoarthritis using digitised radiographs. |
| Impact | Research |
| Start Year | 2006 |
| Description | Osteoarthritis Programme |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Collaborator Contribution | Novel technique for grading osteoarthritis using digitised radiographs. |
| Impact | Research |
| Start Year | 2006 |
| Description | Osteoarthritis: Health Economics |
| Organisation | Cedars-Sinai Medical Center |
| Country | United States |
| Sector | Hospitals |
| PI Contribution | Epidemiological data |
| Collaborator Contribution | Epidemiological data |
| Impact | Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press. |
| Start Year | 2011 |
| Description | Osteoarthritis: Health Economics |
| Organisation | Diakonhjemmet Hospital |
| Department | Department of Rheumatology |
| Country | Norway |
| Sector | Hospitals |
| PI Contribution | Epidemiological data |
| Collaborator Contribution | Epidemiological data |
| Impact | Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press. |
| Start Year | 2011 |
| Description | Osteoarthritis: Health Economics |
| Organisation | Northwestern University |
| Department | Feinberg School of Medicine |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Epidemiological data |
| Collaborator Contribution | Epidemiological data |
| Impact | Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press. |
| Start Year | 2011 |
| Description | Osteoarthritis: Health Economics |
| Organisation | Royal North Shore Hospital and Kolling Institute |
| Country | Australia |
| Sector | Hospitals |
| PI Contribution | Epidemiological data |
| Collaborator Contribution | Epidemiological data |
| Impact | Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press. |
| Start Year | 2011 |
| Description | Osteoarthritis: Health Economics |
| Organisation | University of Lorraine |
| Country | France |
| Sector | Academic/University |
| PI Contribution | Epidemiological data |
| Collaborator Contribution | Epidemiological data |
| Impact | Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press. |
| Start Year | 2011 |
| Description | Osteoarthritis: Health Economics |
| Organisation | University of Maryland |
| Department | Division of Rheumatology & Clinical Immunology |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Epidemiological data |
| Collaborator Contribution | Epidemiological data |
| Impact | Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press. |
| Start Year | 2011 |
| Description | Osteoarthritis: Health Economics |
| Organisation | University of Ottawa |
| Department | Faculty of Medicine |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Epidemiological data |
| Collaborator Contribution | Epidemiological data |
| Impact | Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press. |
| Start Year | 2011 |
| Description | Osteoarthritis: Health Economics |
| Organisation | VU University Medical Center |
| Department | Department of Epidemiology and Biostatistics |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Epidemiological data |
| Collaborator Contribution | Epidemiological data |
| Impact | Hiligsmann M et al. Seminars in Arthritis and Rheumatism 2013; in press. |
| Start Year | 2011 |
| Description | Philipp Thurner |
| Organisation | University of Southampton |
| Department | Faculty of Engineering and the Environment |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research collaboration, bioengineering |
| Collaborator Contribution | Biomechanical expertise |
| Impact | Ongoing |
| Start Year | 2011 |
| Description | Physical activity |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Epidemiological data |
| Collaborator Contribution | Epidemiological data |
| Impact | Collings PJ et al. Am J Clin Nutr 2013;97: 1020-8. Harvey NC et al. Osteoporos Int 2012;23:121-30. Hesketh KR et al. BMC Public Health 2013;13:924. McMinn AM et al. Int J Behav Nutr Phys Act 2009;6:81. |
| Start Year | 2011 |
| Description | Prof Diana Kuh |
| Organisation | University College London |
| Department | MRC Unit for Lifelong Health and Ageing |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2009 |
| Description | Prof Kay-Tee Khaw |
| Organisation | University of Cambridge |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2008 |
| Description | Prof N Wareham |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research collaboration |
| Collaborator Contribution | Research collaboration |
| Impact | Clinical impact |
| Start Year | 2006 |
| Description | Prof Paul Lips |
| Organisation | University of Amsterdam |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2007 |
| Description | Professor Bo Abrahamsen |
| Organisation | University of Southern Denmark |
| Department | Molecular Endocrinology Laboratory (KMEB) |
| Country | Denmark |
| Sector | Academic/University |
| PI Contribution | Population database research |
| Collaborator Contribution | Research |
| Impact | Ongoing |
| Start Year | 2012 |
| Description | Professor Ulf Ekelund |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research collaboration, physical activity monitoring |
| Collaborator Contribution | Research |
| Impact | Original papers |
| Start Year | 2006 |
| Description | Relationship of aldosterone with cortisol and blood pressure |
| Organisation | University of Edinburgh |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Contribution of anonymised phenotypic data |
| Impact | Publications. Pubmed ID: 19380612 |
| Start Year | 2006 |
| Description | SARCOFRAX |
| Organisation | University of Gothenburg |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | Developing sarcopenia outcome risk calculator |
| Collaborator Contribution | Developing sarcopenia outcome risk calculator |
| Impact | ongoing |
| Start Year | 2020 |
| Description | SARCOFRAX |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Developing sarcopenia outcome risk calculator |
| Collaborator Contribution | Developing sarcopenia outcome risk calculator |
| Impact | ongoing |
| Start Year | 2020 |
| Description | Shape Modelling |
| Organisation | University of Aberdeen |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Hip and knee shape modelling for osteoarthritis |
| Collaborator Contribution | Hip and knee shape modelling for osteoarthritis |
| Impact | Hip and knee shape modelling for osteoarthritis |
| Start Year | 2014 |
| Description | Southampton Women's Survey |
| Organisation | Lancaster University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Description | Southampton Women's Survey |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Description | Southampton Women's Survey |
| Organisation | University of Bergen |
| Country | Norway |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Description | Southampton Women's Survey |
| Organisation | University of Cambridge |
| Department | MRC Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Description | Southampton Women's Survey |
| Organisation | University of Oslo |
| Country | Norway |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Description | Southampton Women's Survey |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Description | Southampton Women's Survey |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research |
| Impact | Research |
| Description | UK Biobank |
| Organisation | University of Oxford |
| Department | School of Medicine |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research collaboration |
| Collaborator Contribution | Research collaboration |
| Impact | Emergent analysis of body composition and cardiovascular function in UK Biobank |
| Start Year | 2015 |
| Description | UK Biobank |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | DXA Lead |
| Collaborator Contribution | Other imaging |
| Impact | 1 paper |
| Start Year | 2014 |
| Description | UK Biobank Aberdeen |
| Organisation | University of Aberdeen |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Active shape modelling of joints- epidemiology |
| Collaborator Contribution | Active shape modelling of joints- modelling |
| Impact | Ongoing |
| Start Year | 2015 |
| Description | UK Biobank Bristol |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Determinants of bone mass and fracture risk |
| Collaborator Contribution | Determinants of bone mass and fracture risk |
| Impact | Ongoing |
| Start Year | 2016 |
| Description | UK Biobank Sheffield |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | DXA pixel mapping- epidemiology and UKB |
| Collaborator Contribution | DXA pixel mapping- technical expertise |
| Impact | Ongoing |
| Start Year | 2015 |
| Description | UKB CVD OP |
| Organisation | Queen Mary University of London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | UK Biobank: Associations between BMD, fracture and cardiovascular disease |
| Collaborator Contribution | UK Biobank: Associations between BMD, fracture and cardiovascular disease |
| Impact | UK Biobank: Associations between BMD, fracture and cardiovascular disease |
| Start Year | 2014 |
| Description | University of Helsinki |
| Organisation | University of Helsinki |
| Country | Finland |
| Sector | Academic/University |
| PI Contribution | Research collaboration |
| Collaborator Contribution | Clinical Impact |
| Impact | Clinical impact |
| Start Year | 2006 |
| Description | University of Oxford |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2007 |
| Description | University of Southampton |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research Collaboration |
| Collaborator Contribution | Research Collaboration |
| Impact | Clinical Impact |
| Start Year | 2006 |
| Description | VIBE |
| Organisation | University of Bristol |
| Department | MRC Integrative Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Scientific collaboration |
| Collaborator Contribution | Scientific collaboration |
| Impact | 2 abstracts |
| Start Year | 2013 |
| Description | WHO Clinical Consortium on Health Ageing |
| Organisation | World Health Organization (WHO) |
| Country | Global |
| Sector | Public |
| PI Contribution | Contribution to World Report on Ageing and Health, and project to operationalise concept of intrinsic capacity |
| Collaborator Contribution | Organisation of WHO workshop on intrinsic capacity |
| Impact | WHO Global Report on Ageing and Health |
| Start Year | 2016 |
| Title | Healthy conversation skills worker resource pack. |
| Description | Package of behavioural skills to enhance peer-led initiatives to optimise nutritional behaviour of young women. |
| IP Reference | |
| Protection | Copyrighted (e.g. software) |
| Year Protection Granted | 2012 |
| Licensed | Yes |
| Impact | Multiple collaborations: Australia, USA and Canada. |
| Title | PHENOTYPE PREDICTION |
| Description | Detection of epigenetic alteration, especially methylation, of a gene or a combination of genes, preferably in a perinatal tissue sample such as umbilical cord, for predicting diverse phenotypic characteristics such as propensity for obesity, altered body composition, impaired cognition, low bone mineral content, neuro-behavioural problems and altered cardiovascular structure and function occurring in an individual. |
| IP Reference | WO2007129113 |
| Protection | Patent application published |
| Year Protection Granted | 2007 |
| Licensed | No |
| Impact | Six abstracts and paper in press. |
| Title | PHENOTYPE PREDICTION BY DETERMINING THE METHYLATION STATUS OF GENES |
| Description | Phenotypic characteristics selected from obesity and/or adiposity, bone health, and cardiovascular disease, may be predicted by determining the methylation status of one or more CpG dinucleotides of the, SLC6A4, CDKN2A, FEN1 and BACH1 genes. |
| IP Reference | WO2015067952 |
| Protection | Patent application published |
| Year Protection Granted | 2015 |
| Licensed | No |
| Impact | EpiGen Consortium |
| Title | PREDICTIVE USE OF CPG METHYLATION |
| Description | RXRA for obesity or adiposity, body mass index and limb fat as an indicator of body fat distribution |
| IP Reference | EP2391730 |
| Protection | Patent application published |
| Year Protection Granted | 2011 |
| Licensed | No |
| Impact | EpiGen Consortium |
| Title | PREDICTIVE USE OF CpG METHYLATION |
| Description | Determination of the methylation status of individual selected Cp/G dinucleotides/CpG groups 5' to the coding region of selected genes, preferably in a perinatal tissue sample such as umbilical cord, can be used to predict future development of diverse phenotypic characteristics, such as indices of body composition indicative of for example, obesity or low bone mineral content, indices of impaired cardiovascular structure or function, ability to learn and cognitive function, neurobehavourial problems and allergic disorders such as atopic eczema. |
| IP Reference | US2012040344 |
| Protection | Patent application published |
| Year Protection Granted | 2012 |
| Licensed | Commercial In Confidence |
| Impact | Research contracts with Danone, Abbott and Nestle. |
| Title | Phenotype prediction |
| Description | Detection of epigenetic alteration, especially methylation, of a gene or a combination of genes, preferably in a perinatal tissue sample such as umbilical cord, for predicting diverse phenotypic characteristics such as propensity for obesity, altered body composition, impaired cognition, low bone mineral content, neuro-behavioural problems and altered cardiovascular structure and function occurring in an individual. |
| IP Reference | EP2194143 |
| Protection | Patent application published |
| Year Protection Granted | 2010 |
| Licensed | No |
| Impact | EpiGen Consortium |
| Title | Healthy Conversation Intervention |
| Description | Healthy Conversation Intervention |
| Type | Preventative Intervention - Behavioural risk modification |
| Current Stage Of Development | Early clinical assessment |
| Year Development Stage Completed | 2014 |
| Development Status | Under active development/distribution |
| Impact | Health and Wealth impacts |
| Title | MAVIDOS trial vitamin D intervention |
| Description | Vitamin D supplementation |
| Type | Preventative Intervention - Nutrition and Chemoprevention |
| Current Stage Of Development | Wide-scale adoption |
| Year Development Stage Completed | 2021 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | Maternal vitamin D supplementation led to greater bone mass in the offspring for winter births |
| Title | Maternal vitamin D supplementation in pregnancy |
| Description | MAVIDOS Trial published confirming beneficial effects of 1000 IU cholecalciferol compared with placebo on neonatal bone mass for winter births. |
| Type | Preventative Intervention - Nutrition and Chemoprevention |
| Current Stage Of Development | Late clinical evaluation |
| Year Development Stage Completed | 2017 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | Modification of national and international nutritional guidelines. |
| URL | https://www.clinicaltrialsregister.eu/ctr-search/search?query=eudract_number:2007-001716-23 |
| Title | Odanacatib |
| Description | Data Monitoring Committee for major phase III trial of Odanacatib in prevention of osteoporotic fracture. |
| Type | Therapeutic Intervention - Drug |
| Current Stage Of Development | Refinement. Clinical |
| Year Development Stage Completed | 2013 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | Large international phase III trial. |
| URL | http://clinicaltrials.gov/show/NCT00529373 |
| Title | SPRING Pregnancy vitamin D supplementation trial |
| Description | Trial of vitamin D supplementation during pregnancy |
| Type | Preventative Intervention - Nutrition and Chemoprevention |
| Current Stage Of Development | Wide-scale adoption |
| Year Development Stage Completed | 2021 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| Impact | Trial of vitamin D supplementation during pregnancy |
| Title | Strontium ranelate and knee osteoarthritis |
| Description | First discovered disease-modifying agent for knee osteoarthritis |
| Type | Therapeutic Intervention - Drug |
| Current Stage Of Development | Late clinical evaluation |
| Year Development Stage Completed | 2012 |
| Development Status | Under active development/distribution |
| Clinical Trial? | Yes |
| UKCRN/ISCTN Identifier | European Trial (EMA registered) |
| Impact | Attenuation of cartilage loss in OA. |
| Title | Healthy Conversation Skill Behavioural Package |
| Description | Peer led intervention package for young women aiming to optimize nutrition and physical activity |
| Type Of Technology | Webtool/Application |
| Year Produced | 2017 |
| Open Source License? | Yes |
| Impact | Multiple use in South Africa, New Zealand, Malaysia, Singapore |
| Description | "Meet the Expert Workshop" 2-4 December 2018, Kate Ward |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Kate Ward led a "Meet the Expert Workshop" at the 2018 National Osteoporosis Society Annual Conference which took place in Birmingham from 2nd to 4th December 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | 114th Annual Meeting of the Association of Physicians |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this online meeting on 16th March 2021. This was a APAM online Inauguration. The meeting was hosted by University of Oxford. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://aopgbi.org/ |
| Description | 14th EUGMS Conference, Berlin, 10-11th October 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attendance and lecture at the 14th EUGMS held on the 10-11th October in Berlin |
| Year(s) Of Engagement Activity | 2018 |
| Description | 2017 World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases, Florence |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Scientific Committee Chairperson for this event in Florence, Italy on 15th June 2017. The event was captured online, twitter, facebook and email |
| Year(s) Of Engagement Activity | 2017 |
| Description | 2018 National Osteoporosis Society Annual Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | A number of MRC LEU investigators attended the 2018 National Osteoporosis Society Annual Conference. Young Investigator Awards were received by Beth Curtis, Millie Parsons, Michael Clynes and Nick Fuggle. Kate Ward led a Meet the Expert Workshop and Professors Cyrus Cooper and Nick Harvey also gave major invited plenary presentations. Nick and Kate are also members of the Conference Organising Committee. There was a lot of social media activity surrounding this event. |
| Year(s) Of Engagement Activity | 2018 |
| Description | 28th Seah Cheng Memorial Lecture, Singapore, 15-18th September 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus was invited to give the keynote address at the Academy of Medicine, Singapore on 'Osteoarthritis - from paediatric days to geriatric times'. |
| Year(s) Of Engagement Activity | 2018 |
| Description | 45th European Calcified Tissue Society Conference in Valencia from 28-29th May 2018 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Provided lecture and attendance at the 45th European Calcified Tissue Society Conference |
| Year(s) Of Engagement Activity | 2018 |
| Description | 500th baby born in MAVIDOS study |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Type Of Presentation | Keynote/Invited Speaker |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Articles announcing 500th baby born in MAVIDOS study: Meridian TV; Southern Daily Echo; University of Southampton website. Increased recognition of LEU science |
| Year(s) Of Engagement Activity | 2012 |
| Description | 8th IOF Asia Pacific Regional Conference Programme, IOF Regional Bangkok |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this conference, and gave a talk entitled 'Osteoporosis Management in 2021: South Asia meets Europe'. This took place on 1st December 2021. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.iof-regional.org |
| Description | 9th International Conference on Osteoporosis and Bone Disease, China 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Gave 2 lectures at the 9th International Conference on Osteoporosis and Bone Disease, chaired 2 events |
| Year(s) Of Engagement Activity | 2018 |
| Description | A blog welcoming Professor Cyrus Cooper to their new trustee |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | The Medical Research Foundation added to their blog to welcome Cyrus Cooper as their new trustee. Cyrus was nominated by the MRC and his term will be until 2020 |
| Year(s) Of Engagement Activity | 2017 |
| Description | A press release issued for a paper which was published in the University of Southampton News and Medicalxpress |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Undergraduate students |
| Results and Impact | Press release on 'Relationships between markers of inflammation and muscle mass, strength and function: Findings from the Hertfordshire Cohort Study. |
| Year(s) Of Engagement Activity | 2017 |
| Description | ACMEDSCi starter grants panel |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper became a member of the panel on 11 June 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://acmedsci.ac.uk/grants-and-schemes/grant-schemes/starter-grants |
| Description | ASBMR Annual Conference, Atlanta, USA - Plenary Lectures |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | ASBMR Annual Conference, Atlanta, USA - Plenary Lectures |
| Year(s) Of Engagement Activity | 2016 |
| Description | ASBMR debate, Montreal |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Major international debate |
| Year(s) Of Engagement Activity | 2015 |
| Description | ASBMR nutrition WG |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | ASBMR nutrition WG, invited presentation of MAVIDOS study |
| Year(s) Of Engagement Activity | 2015 |
| Description | ASBMR online (EC) 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation at ASBMR, USA |
| Year(s) Of Engagement Activity | 2021 |
| Description | ASBMR presentation (BC) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Beth Curtis presented MAVIDOS 4 year bone results |
| Year(s) Of Engagement Activity | 2019 |
| Description | ASBMR-ECTS debate EC 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | ASBMR-ECTS debate EC 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Abstract presentation ASBMR online 2020 (EC) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Abstract presentation ASBMR online 2020 (EC) |
| Year(s) Of Engagement Activity | 2020 |
| Description | Abstract presentation ASBMR online 2020 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Abstract presentation ASBMR online 2020 (NCH) |
| Year(s) Of Engagement Activity | 2020 |
| Description | Academy Advisory Committee Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 21st April 2021. The meeting was attended by over 10 people. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.theros.org.uk |
| Description | Academy of MedicalSciences 18th Forum Annual Lecture |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus was invited to the Academy of Medical Sciences 18th Forum Annual Lecture entitled "Technology to support sustainability of health and social care systems". The speakers were Professor John Rogers, Director of the Querry Simpson Institute for Bioelectronics at Northwestern University and other distinguished speakers who explore the role of new technologies, such as biosensors, wearables, smarthomes and AI, in helping to enable remote care, prevent ill health and improve wellbeing. Attendance was 100+, ATTENDEES WERE MEDIA. This was held on 12 October 2020. |
| Year(s) Of Engagement Activity | 2020 |
| Description | AmGen PFC Steering Committee Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus is a member of this Steering Committee which was held on 22nd May 2020. |
| Year(s) Of Engagement Activity | 2020 |
| Description | American College of Rheumatology, Atlanta 11-14th Nov 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper lectured at the American College of Rheumatology and ARP Annual Meeting in Atlanta in November 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | American Society for Bone and Mineral Research in Montreal from 28th September to 1st October 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | International Meeting in Montreal for the American Society for Bone and Mineral Research, presented a lecture and full attendance |
| Year(s) Of Engagement Activity | 2018 |
| Description | Annual European Congress of Rheumatology EULAR, Madrid, June 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Cooper shared his expertise and knowledge by lecturing on "Case 1 discussant: Imminent fracture risk: assessment and does it help clinical management" with a particular session on "Predicting short-term fracture risk: can we foresee the (close) future?" |
| Year(s) Of Engagement Activity | 2019 |
| Description | Appointment to non-executive director of hospital trust |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | The University of Southampton Medicine News Page reported that Professor Cyrus Cooper has been appointed as non-executive director of hospital trust. |
| Year(s) Of Engagement Activity | 2018 |
| Description | ArLAR Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cyrus Cooper was an invited speaker at the Conference. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.arabrheumatology.org/ |
| Description | Arthritis Research Sub-Committee in Chesterfield on 23rd May 2018 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Arthritis research sub-committee meeting in Chesterfield on 23rd May 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Arthritis Research UK Pain Workshop, Wellcome Trust, London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Arthritis Research UK Pain Workshop, Wellcome Trust, London |
| Year(s) Of Engagement Activity | 2016 |
| Description | Article appeared in Healio with quotes by Nick Harvey regarding findings in his paper which was published in July 2018 |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | An article appeared in healio with quotes by Nick Harvey regarding the findings in his paper which was published in July 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Article attracted great deal of media attention |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Hill WD, Marioni RE, Maghzian O, Ritchie SJ, Hagenaars SP, McIntosh AM, Gale CR, Davies GA combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. Molecular psychiatry 2018/01/11 doi 10.1038/s41380-017-0001-5. This article attracted a great deal of media attention - as well as appearing in a number of newspapers it was tweeted by 467 people, was on 7 facebook pages, mentioned in 3 Google+ posts, picked up by 14 news outlets, 4 Reddit and 2 videos, plus 54 readers on Mendeley. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Article entitled "higher inflammation in older age is linked to lower bone density" appeared in the University of Southampton medicine news and in the medicalexpress website |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Undergraduate students |
| Results and Impact | Article entitled "higher inflammation in older age is linked to lower bone density" appeared in the University of Southampton medicine news and in the medicalexpress website |
| Year(s) Of Engagement Activity | 2018 |
| Description | Article for NRAS on Osteoporosis and Rheumatoid Arthritis (ED) |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Review article designed to promote awareness of coexistence of comorbidity in RA, leading to enquiries from interested patients via the website |
| Year(s) Of Engagement Activity | 2010,2015 |
| Description | Article in National newspaper |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | The Guardian newspaper published an article entitled 'Murder Mystery to DNAL researchers bring science to life in schools.' The article covered the benefits of introducing school pupils to science in a laboratory environment. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Article published on two websites |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | This article attracted some media attention and appeared on two websites and the University of Southampton enews. The articles were entitled 'Poorer health influences muscle strength in later life'. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Article submitted for the 8th December edition of the Friday blog |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Karen Walker-Bone and Cyrus Cooper submitted an article entitled 'Good work is good for us'. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Articles on MAVIDOS findings appeared on website articles and facebook |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Articles on MAVIDOS findings appeared on the University of Southampton website, World News website; Publicnow.com. It was also mentioned on a number of Facebook pages including, University of Southampton; International Osteoporosis Foundation and Resilient Bones. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Association of Physicians Annual meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation of MAVIDOS CTX data by Beth Curtis |
| Year(s) Of Engagement Activity | 2019 |
| Description | BBC Interview in Singapore for International News |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Cyrus Cooper gave an interview on BBC World News addressing recent advances in the risk assessment and treatment of osteoporosis. |
| Year(s) Of Engagement Activity | 2018 |
| Description | BBC News: Vitamin D boosts child muscles |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Extensive feedback |
| Year(s) Of Engagement Activity | 2014 |
| Description | BHF Chair |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper was Chair of this BHF meeting, which was held on 20th May 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.bhf.org.uk/ |
| Description | BMFMS, Amsterdam |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | BMFMS, Amsterdam |
| Year(s) Of Engagement Activity | 2016 |
| Description | BRC Science Forum Friday |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | During the current pandemic, NIHR Southampton Biomedical Research Centre hold a weekly forum to discuss the latest research. All staff with a University of Southampton login to Teams can access the recordings of these talks. Cyrus Cooper gave his talk on Lifecourse Epidemiology of Musculoskeletal Disorders on 12th January 2021. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://web.microsoftstream.com/video/0cd14716-d313-4398-b541-52df9e72aa54?referrer=https:%2F%2Fwww.... |
| Description | Bisphosphonates 50th Anniversary Meeting, July 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Professor Cooper gave a talk entitled 'the treatment gap' at the Bisphosphonates 50th Anniversary Meeting, Sheffield, July 2019 |
| Year(s) Of Engagement Activity | 2019 |
| Description | Blog |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cyrus Cooper discussed how and why we should preserve creativity in times of crisis on both a personal and professional level. Blog attached. Blog was called Medically speaking. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Blog for the University of Southampton |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Regular broadcast while giving a talk in Geneva. It was one week after the general election. It made Cyrus more aware of the impact the election and Brexit would have on the work we do |
| Year(s) Of Engagement Activity | 2017 |
| Description | Blog on global outreach of the research of the MRC LEU |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Stimulating increased interest in research globally in the research of the MRC. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Blog written by Cyrus Cooper and Nick Harvey which appeared in the Medically Spekaing section of the Unviersity of Southampton website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Undergraduate students |
| Results and Impact | Cyrus Cooper and Nick Harvey wrote a blog which appeared in the "Medically Speaking" section of the University of Southampton website. Their blog was about the National Osteoporosis Society Annual Osteoporosis Conference, at which four members of the MRC LEU, Beth Curtis, Millie Parsons, Nick Fuggle and Michael Clynes all received young investigator awards. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Bone Research Society Annual Scientific Meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Beth Curtis presentation on bone turnover in MAVIDOS at BRS |
| Year(s) Of Engagement Activity | 2019 |
| Description | Bone Research Society Event Speaker and Organising Committee |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Part of the organising committee for the Bone Research Society Conference in Winchester from 27th - 30th June 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Bone Research Society Training Course, Oxford |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attended and ran a session at the Bone Research Society Training Course at Oxford in March 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Bone Research Society, Edinburgh |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Major invited lecture |
| Year(s) Of Engagement Activity | 2015 |
| Description | British Menopause Society Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus was an invited speaker, his talk was entitled "Management Options for postmenopausal osteoporosis prevention". Due to COVID 19, the event was held virtually and attended by 200+ professional practitioners on 2nd July 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://thebms.org.uk/ |
| Description | British Orthopedic Research Society Keynote lecture (EMD) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | British Orthopedic Research Society Keynote lecture |
| Year(s) Of Engagement Activity | 2017 |
| Description | British Rheumatology Society Clinical Training Course, Oxford, 18th March 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper lectured at the BRS Clinical Training Course on the Epidemiology of Osteoporosis |
| Year(s) Of Engagement Activity | 2019 |
| Description | British Society for Rheumatology, Birmingham |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Major invited lecture |
| Year(s) Of Engagement Activity | 2015 |
| Description | British Society of Rheumatology Annual Meeting Manchester (ED) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chair of debate to discuss musculoskeletal aging, leading to greater awareness among colleagues and other interested parties |
| Year(s) Of Engagement Activity | 2015 |
| Description | CCA Meeting, Geneva - invited lecture |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | CCA Meeting, Geneva - invited lecture |
| Year(s) Of Engagement Activity | 2016 |
| Description | CMHW Bi monthly steering telecom |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper attended the meeting which was held on 13th August 2020. |
| Year(s) Of Engagement Activity | 2020 |
| Description | CTI manuscript press release (ME) |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Calcified Tissue International manuscript on sarcopenia and dysmobility. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Calcium and Vitamin D supplementation are not associated with risk of incident ischemic cardiac events or death: findings from the UK Biobank Cohort - press release |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Press release created a lot of media interest for this paper. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Chair ASBMR IOF joint session at ASBMR 2021 (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Chair ASBMR IOF joint session at ASBMR 2021 (NCH) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Cheltenham Science Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Type Of Presentation | Workshop Facilitator |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | MRC stand at Cheltenham Science festival. LEU staff contributed/ LEU work covered Interaction with national public audience |
| Year(s) Of Engagement Activity | 2008,2009,2010,2011,2012 |
| Description | Chinese Society of Osteoporosis and Bone Mineral Research |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended the Chinese Society of Osteoporosis and Bone Mineral Research Calcium and Multivitamin Forum which was held online. There were 100+ at the event. The event was held on 11th September 2020. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Conference IOF Florence March 2017 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The members of the Committee of Scientific Advisors of the International Osteoporosis Foundation (IOF) and the Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) are developing a very exciting Congress' scientific programme that will bring together the world's best in the field of musculoskeletal health and disease. We really hope to welcome you in Krakow, Poland and that this Congress will move the field one step forward on all fronts; from new understanding of bone metabolism and pathology, to new strategies and options in prevention, diagnosis and treatment. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Conferences |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Type Of Presentation | Keynote/Invited Speaker |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Many talks and posters presented at a wide range of conferences Increased communication with the scientific community and the general public about our work |
| Year(s) Of Engagement Activity | 2006,2007,2008,2009,2010,2011,2012 |
| Description | Copenhagen Seminar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cyrus Cooper lectured at the conference 'The Skeleton from Early Life to Old Age - new paradigms in osteoporosis and bone health'. The lecture from Prof Cooper was extremely well attended by international leaders in the medical profession and was entitled "Global disease burden and Life Course Epidemiology of osteoporosis". |
| Year(s) Of Engagement Activity | 2019 |
| Description | Cutting Edge Osteoarthritis Meeting, Pembroke College, Oxford, June 2019 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cyrus Cooper attended and delivered a talk on 'Inspired Careers' at the third Cutting Edge Osteoarthritis Meeting at Pembroke College, Oxford on 24-25 June 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Cyrus Cooper and Keith Godfrey - Clarivate Highly Cited Researchers |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Both Cyrus Cooper and Keith Godfrey received congratulations for being among 2018s highly cited researchers. They were included in the Clarivate Analytics listings and also mentioned on the University of Southampton website. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Cyrus Cooper was interviewed for an article that was published in the Telegraph as a result of the paper that was published in the BMJ on Vitamin D. |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Cyrus Cooper was interviewed for an article that was published in the Telegraph as a result of the paper that was published in the BMJ on Vitamin D. His comments included: Cyrus Cooper, Professor of Rheumatology at the University of Southampton and President of the International Osteoporosis Foundation who contributed to the study said that bone density was probably some two to three times better at predicting someone's risk of getting osteoporosis than their level of Vitamin D level. "I don't think this paper debunks the idea that Vitamin D is useful", he said. "It's just that it is a small determinant. You'd do some good if you make sure that your Vitamin D levels are okay." Commenting on the current UK advice for management and prevention of osteoporosis he said: "The current guidelines are appropriate however a bone density evaluation needs to be done as part of fracture risk screening". |
| Year(s) Of Engagement Activity | 2018 |
| Description | DHSC/UKRI COVID 19 Rapid Response Call |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 21 May 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://mrc.ukri.org/news/browse/coronavirus-updates/ |
| Description | DOHaD World Congress, Cape Town |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Lecture |
| Year(s) Of Engagement Activity | 2015 |
| Description | Daily Echo MAVIDOS |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Type Of Presentation | Keynote/Invited Speaker |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Coverage of MAVIDOS 500th baby in daily paper (Daily Echo) Regional coverage via paper and website |
| Year(s) Of Engagement Activity | 2012 |
| Description | Daily Mail vitamin D article |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Interview on vitamin D to inform Daily Mail research |
| Year(s) Of Engagement Activity | 2017 |
| Description | Data Transparency Board, September, Paris 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Prof Cooper attended and spoke at the Data Transparency Board Meeting with Servier on 23rd September 2019 in Paris. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Donald Acheson's Festschrift |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | Yes |
| Type Of Presentation | Keynote/Invited Speaker |
| Geographic Reach | International |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | 300 attendees with widespread media coverage. Local newspaper and TV accolades. |
| Year(s) Of Engagement Activity | 2011 |
| Description | Donation from Wessex Heartbeat of £200,000 in the LifeLab programme to help region's chldren lead a healthier life |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Undergraduate students |
| Results and Impact | News of the donation was on the University of Southampton website under medicine and lifelab news, daily echo website and newspaper, and deepsouth media. |
| Year(s) Of Engagement Activity | 2017 |
| Description | EAG teleconference: Osteoporosis and Fragility Fractures Policy Network |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper attended this online conference on 14th May 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.osteopolicynetwork.org/ |
| Description | EAG teleconference: Osteoporosis and Fragility Fractures Policy Network |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 16th September. The meeting was called 'ASBMR Secondary Fracture Prevention Initiative, Full Coalition Call' |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.osteopolicynetwork.org |
| Description | ECTS 2021 Congress |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper gave a presentation entitled: 'Building Bones in Young Individuals' at the ECTS 2021 Congress. This was attended by over 100 people. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.ects2021.org |
| Description | ECTS Conference, Rome. Keynote Lecture |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | ECTS Conference, Rome. Keynote Lecture |
| Year(s) Of Engagement Activity | 2016 |
| Description | ECTS Congress |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper was an invited Speaker at this three day conference, which took place between 22-24th October 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.ects2020.org/ |
| Description | ECTS, Salzburg 13-16 May |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | ECTS, Salzburg 13-16 May |
| Year(s) Of Engagement Activity | 2017 |
| Description | EGG Consortium |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cyrus Cooper attended this meeting in May 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | http://www.egg-consortium.org/ |
| Description | ESCEO |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | "Alternative treatments for OA" Working Group and the "Biochemical markers" WG. |
| Year(s) Of Engagement Activity | 2019 |
| Description | ESCEO Phosphate Wasting Workshop (NCH, CC) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | ESCEO Phosphate Wasting Workshop (NCH, CC) |
| Year(s) Of Engagement Activity | 2021 |
| Description | ESCEO Working Group, 20th March 2018 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Attendance and presented at ESCEO International Working Group on 20th March 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | ESCEO Working Group, Venice, October 2019 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Prof Cooper provided vital information at the working group meeting in Venice in October 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | ESCEO Working Groups, Geneva - Invited Lecture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Vitamin D Meeting, London - Invited Lecture |
| Year(s) Of Engagement Activity | 2016 |
| Description | ESICON Congress, New Delhi. Plenary Lecture |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | ESICON Congress, New Delhi. Plenary Lecture |
| Year(s) Of Engagement Activity | 2016 |
| Description | EWGSOP2/EUGMS in Amsterdam on 4th June 2018 |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Supporters |
| Results and Impact | Attendance and spoke at the EWGSOP2/EUGMS in Amsterdam on 4th June 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Edinburgh Science Festival |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Type Of Presentation | Keynote/Invited Speaker |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Lecture Feedback excellent; media attention; future research informed |
| Year(s) Of Engagement Activity | 2007,2010 |
| Description | Enews email University of Southampton, Faculty of Medicine and Daily Echo, Deccan Chronical and Medical Xpress |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sarah El Heis and Cyrus Cooper submitted paper entitled 'Maternal Stress and psychological distress preconception: association with offspring atopic eczema at age 12 months' to University of Southampton Faculty of Medicine and local newspapers. This paper received media attention from the University and the Daily Echo. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Enews, University of Southampton: QQR renewal; and David Barker Research Prize (CC) |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Other audiences |
| Results and Impact | Enews, University of Southampton: QQR renewal; and David Barker Research Prize awarded to CC. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Expert Opinion |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Nick Harvey answered questions from the Daily Mail regarding Vitamin D formulations |
| Year(s) Of Engagement Activity | 2017 |
| Description | Expert Panel Sarcopenia, 12-14th November 2018, Boston |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Attended Expert Panel Meeting on Sarcopenia in Boston from 12-14th November 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | FRAX Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attending a FRAX meeting, held by University of Sheffield on 4th March 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Faculty of Medicine Conference, University of Southampton |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper attended this Conference on 8th October 2020. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Faculty of Medicine eNews Blog: CC |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Other audiences |
| Results and Impact | Faculty of Medicine eNews blog: CC |
| Year(s) Of Engagement Activity | 2016 |
| Description | Fake Food Event Feedback |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | Sian Robinson was one of the six panellists at the Fake Food event which took place at Lecture Theatre 1, SAB, Southampton General Hospital. The panel were asked questions by groups of local sixth formers who had been invited to the event. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Fellowship Committee Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus attended this meeting on 10th May 2021. There were over 100 people in attendance. |
| Year(s) Of Engagement Activity | 2021 |
| URL | http://www.acmedsci.ac.uk |
| Description | Findings from the paper 'Calcium and Vitamin D supplementation are not associated with risk of incident ischemic cardiac events or death' appeared in the Hippocratic Post and other media |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Findings from the paper 'Calcium and Vitamin D supplementation are not associated with risk of incident ischemic cardiac events or death: Findings from the UK biobank cohort. J Bone Miner Res. 2018 May;33(5):803-811. doi: 10.1002/jbmr.3375, epub 2018 Feb 8'. appeared in the Hippocratic Post, on other websites, on 3 facebook pages, 34 tweets, and 1 blog. |
| Year(s) Of Engagement Activity | 2018 |
| Description | General media activity |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Many interviews with journalists. Filming by various TV companies. Radio interviews and contributions to documentaries Increased understanding of our work by the public |
| Year(s) Of Engagement Activity | 2006,2007,2008,2009,2010,2011,2012,2013,2014 |
| Description | Gestational vitamin D supplementation leads to reduced perinatal RXRA DNA methylation: results from the MAVIDOS trial - press release |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | https://www.southampton.ac.uk/medicine/news/2018/11/vitamin-d-baby-genes.page; https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbmr.3603 Gestational vitamin D supplementation leads to reduced perinatal RXRA DNA methylation: results from the MAVIDOS trial. Journal of Bone and Mineral Research. 2018 doi.10.1002/jbmr.3603 Curtis EM, Krstic N, Cook E, D'Angelo S, Crozier SR, Moon RJ, Murray R, Garratt Em, Costello P, Cleal J et al (inc Godfrey K, Cooper C and Harvey N). |
| Year(s) Of Engagement Activity | 2018 |
| Description | Health Policy Partnership virtual meeting |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper attended this meeting on 26th May 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.healthpolicypartnership.com/project/osteoporosis-and-fragility-fractures/ |
| Description | Herfordshire Open Day in Harpenden on 23rd June 2018 |
| Form Of Engagement Activity | Participation in an open day or visit at my research institution |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Study participants or study members |
| Results and Impact | Attendance at the Herfordshire Open Day on 23rd June in Harpenden |
| Year(s) Of Engagement Activity | 2018 |
| Description | Hertfordshire Public Meeting |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Study participants or study members |
| Results and Impact | Approximately 300 HLS participants and their families attended an open day, which led to discussion, questions and interest in future research studies. |
| Year(s) Of Engagement Activity | 2018 |
| Description | High Commissioner, Singapore 17-18th September 2018 |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | During the visit he was invited to a discussion on UK-Singapore research collaborations at Eden Hall, the residence of His Excellency Mr Scott Wightman, UK High Commissioner to Singapore. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Horizon BBC TV |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | Yes |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Wide dissemination of MRC funded research. A second BBC Horizon TV programme commissioned. |
| Year(s) Of Engagement Activity | 2011 |
| Description | ICCBH presentation (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Lecture on children's bone health |
| Year(s) Of Engagement Activity | 2017 |
| Description | ICFSR Annual Congress, Philadelphia, Keynote Lecture |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | ICFSR Annual Congress, Philadelphia, Keynote Lecture |
| Year(s) Of Engagement Activity | 2016 |
| Description | ICFSR, Barcelona |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | ICFSR, Barcelona |
| Year(s) Of Engagement Activity | 2017 |
| Description | ICFSR, Miami 16th-25th February 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Speaking at the ICFSR 2019 international conference in Miami in February 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | IOF CTF Webinar (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | IOF CTF Webinar |
| Year(s) Of Engagement Activity | 2018 |
| Description | IOF ESCEO WCO, Florence |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | IOF ESCEO WCO, Florence |
| Year(s) Of Engagement Activity | 2016 |
| Description | IOF ESCEO meeting, Geneva |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | IOF ESCEO meeting, Geneva |
| Year(s) Of Engagement Activity | 2017 |
| Description | IOF Medal of Achievement Award: Prof Cyrus Cooper |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Type Of Presentation | Keynote/Invited Speaker |
| Geographic Reach | International |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | Articles announcing the award of the IOF Medal of Achievement to Prof Cyrus Cooper appeared on various websites including St Peter's College, Oxford University; University of Southampton, and www.news-medical.net/news/20120326. Increased recognition of LEU science |
| Year(s) Of Engagement Activity | 2012 |
| Description | IOF Meeting, Geneva - Invited Lecture |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | IOF Meeting, Geneva - Invited Lecture |
| Year(s) Of Engagement Activity | 2016 |
| Description | IOF Regionals, Singapore, Plenary lectures and chairing commitments |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | IOF Regionals, Singapore, Plenary lectures and chairing commitments |
| Year(s) Of Engagement Activity | 2016 |
| Description | IOF WCO Florence ESCEO Symposium (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Lecture on imminent fracture risk in scientific symposium |
| Year(s) Of Engagement Activity | 2017 |
| Description | IOF/ ESCEO working group OA (EMD) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | IOF/ ESCEO working group OA (EMD) |
| Year(s) Of Engagement Activity | 2017 |
| Description | IOF/CTF Partnership Webinar |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper attended this online webinar, which was held on 4th September 2020. |
| Year(s) Of Engagement Activity | 2020 |
| Description | ISCD Conference, Galway, Ireland, Plenary lectures and chairing |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | ECTS Conference, Rome. Keynote Lecture |
| Year(s) Of Engagement Activity | 2016 |
| Description | ITV News article (interview with CC) re "New hope for people with osteoporosis" |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | News article for published paper in Osteoporosis International 2015; 26: 1893-1901. |
| Year(s) Of Engagement Activity | 2015 |
| Description | International Award for Publishing Excellence |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | The authors received this international award for a paper that they published. |
| Year(s) Of Engagement Activity | 2016 |
| Description | International Conference of National Institute on Aging and American Geriatric Society, Bethesday, March 2019 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper presented at this prestigious event on 'Epidemiology: Life trajectories of lean, fat and bone mass'. |
| Year(s) Of Engagement Activity | 2019 |
| Description | International Conference on Frailty and Sarcopenia Research, Miami, 1st - 3rd March 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Attended and presented at the International Conference on Frailty and Sarcopenia Research from 1st - 3rd March 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | International Osteoporosis Foundation Congress on Osteoporosis (ED) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Workshop to disseminate information regarding current European collaboration into osteoarthritis, sparking questions and discussion |
| Year(s) Of Engagement Activity | 2015 |
| Description | International publicity around vitamin D supplement study (NCH, RJM), including live BBC Scotland interview (NCH) |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | International publicity around vitamin D supplement study (NCH, RJM), including live BBC Scotland interview (NCH) |
| Year(s) Of Engagement Activity | 2019 |
| Description | Interview Rosemary Lobley of HEQ |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Cyrus Cooper gave an interview to Rosemary Lobley of HEQ about Osteoporosis, diagnosis, prevention, and treatment. The article is from issue 16 of Health Europa. The date of the interview was 17th February 2021. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.healtheuropa.eu/osteoporosis-diagnosis-prevention-and-treatment/105953/ |
| Description | Interview for website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper was interviewed for an online article entitled 'Osteoporosis prevention can start in the womb.' This was done by Euractiv. He was quoted throughout the article. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.euractiv.com/section/health-consumers/news/osteoporosis-prevention-can-start-in-the-womb... |
| Description | Interview for website |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper gave an interview entitled 'Osteoporosis diagnosis, prevention, and treatment .' to a website on February 17th 2021. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://www.healtheuropa.eu/osteoporosis-diagnosis-prevention-and-treatment/105953/ |
| Description | Interview for website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper gave an online interview for 'Spinal Surgery News' The title of it was 'How Capture the Fracture initiative aims to reduce secondary fracture occurrence.' |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.spinalsurgerynews.com/2020/09/how-capture-the-fracture-initiative-aims-to-reduce-seconda... |
| Description | Interview/videoconference for Healthsense, Australia |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Cooper took part in Interview time for research on global musculoskeletal health strategy development which took place on 23rd June 2020. |
| Year(s) Of Engagement Activity | 2020 |
| URL | http://healthsense_aust@bigpond.com |
| Description | Invited ASBMR Webinar (NCH) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited ASBMR Webinar (NCH) |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited Chair joint IOF SIBOMM session (NCH) 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited Chair joint IOF SIBOMM session (NCH) 2021 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Invited Presentation on vitamin D in pregnancy (NCH); 6th International Maternal Fetal Health congress Turkey |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Presentation on vitamin D in pregnancy (NCH); 6th International Maternal Fetal Health congress Turkey |
| Year(s) Of Engagement Activity | 2018 |
| Description | Invited lecture (CC): 24th Annual Gregory Lecture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited presentation on vitamin D in pregnancy, including MAVIDOS |
| Year(s) Of Engagement Activity | 2016 |
| Description | Invited lecture (CC): British Rheumatology Society |
| Form Of Engagement Activity | |