MRC Centre for Regenerative Medicine

Lead Research Organisation: University of Edinburgh
Department Name: MRC Centre for Regenerative Medicine

Abstract

This proposal represents a request for the renewal of the Edinburgh Centre for Regenerative Medicine. Our Centre tackles a major problem in modern medicine - the lack of any therapies that promote repair in the clinic. At present, a trip to the doctor will lead to a drug to limit the damage from getting worse, but nothing to repair the damage already done. This lack of regenerative therapies is a huge societal and medical problem - for example in Multiple Sclerosis it causes the majority of the 10 billion Euro annual cost of the disease.

To develop this new class of drugs we need to study stem cells, the immortal cells present in many of our tissues that can generate all the cells required for repair. Despite spectacular advances in our understanding of their properties when growing in dishes in the lab, however, we still know very little about what controls their behaviour in tissues, and particularly in tissues damaged by disease or scarring. It is this problem that represents the starting point of our Centre's quest for new treatments.

To tackle this problem we bring together scientists who can address all of the specific questions we need to consider - how do stem cells react to damage, how is their proliferation regulated in tissues, can we increase this proliferation by drugs or by transplanting in new cells and, even if we do, will these new cells be incorporated into and repair the damaged tissue? We also need to partner these scientists with technologists and doctors able to develop our discoveries into products and then try them out in special clinics where very small numbers of highly-selected patients are given these experimental treatments to see if they work.

In working on this, we have two other very important goals. First, we need to train the next generation of clinical and non-clinical scientists in this field so as to ensure that the investment made is sustainable. We select the brightest and the best each year for our PhD programme and provide them with a state-of-the-art training in all areas of stem cells and regenerative medicine, and then help them start their own independent careers. Second, we need to tell the public and politicians what it is we do and why it is important. For this, we have a an Outreach programme (the best in Europe) that provides accurate information on all aspects of stem cells via the press, the web and in person - a vital role to ensure that misconceptions about stem cells are not allowed to spoil the promise of this most exciting area of science.

Technical Summary

The proposed research of the Centre over the next 5 years is comprised of three parts.

First, our research programmes addressing key gaps in fundamental knowledge (tissue stem cells, plutipotent stem cells, niche composition and regulation, activation of tissue stem cells, stem cell differentiation and reprogramming), translation (drug-based therapies, cell-based therapies, disease modelling) and clinical application (cell therapies for liver disease, regenerative neurology) that represent the continuation of our activities catalysed by the initial Centre award - these programmes are now funded by programme and project grants.

Second, the new collaborations and strategic initiatives we propose to achieve our ambition of being world-leading in the field of stem cell and tissues - it is to create these new collaborations and initiatives for which we seek MRC support in this renewal application.

Third, the new translational and clinical platforms for which we propose to leverage our MRC Centre status, and the explicit recognition by the MRC of our ambition, to generate additional funding from other sources. These are an academic cell therapy unit and an endogenous repair platform to contribute to the UK Regenerative medicine platform and a new clinical programme in cardiovascular regeneration in partnership with the BHF.

From this research we will deliver a detailed understanding of the array of external and internal signals that instruct stem cell behaviour and tissue formation, show how disease modifies these signals and identify the steps in the regenerative process at which repair then fails. Using this knowledge, we will generate better animal- and iPS-based models of relevant diseases. We will use these to devise strategies to promote regeneration that we will test in first-in-man clinical trials, so using our facilities and our vision to deliver the crucial next impacts in stem cell biology and regenerative medicine.

Planned Impact

In the short term our work will impact on

1) Commercial organizations ranging from spin-outs using our expertise or IP (eg Roslin Cells or FibroMed) to larger companies with whom we will develop partnerships around areas of specific knowledge eg iPS cells. We see the latter as a particularly important potential impact to address the rapidly declining number of new drugs emerging from the Pharma pipeline. The complexity of safety, regulatory and other hurdles that need to be overcome means that a new drug now costs upward of £1 billion to develop and bring to market. This combination of rising costs and diminishing products is not sustainable, and new technologies are required to improve efficiency. The increased use of ES or iPS-derived human cells provides such a technology.

2) The public, for whom our communications strategy provides accurate information on a range of stem cell-related issues. As an exemplar, there is a need to distinguish the difference between cell replacement strategies based on stem cells and those based on trophic effects of (any) cell transplant. The failure to distinguish these underpins much stem cell tourism and highlights the need for professional outreach programmes such as that in CRM.

3) Policy makers, to whom we provide advice on the opportunities and threats created by stem cell medicine in the life science sector - one of five targeted areas for development in the Scottish economy and a key part of the wider UK economy.

In the longer term the key beneficiaries will be

1) Patients with diseases such as liver cirrhosis, Parkinson's disease and multiple sclerosis. While the identification of neural and other tissue stem cells raises the hope that previously unattainable restoration of other adult organs damaged by disease, trauma or aging can be achieved, there are at present very few regenerative therapies in the clinic - doctors prescribe drugs to limit damage, but none to enhance repair. Such regenerative therapies, which ight be either cell- or drug-based, represent a major unmet need.

2) Blood transfusion services. Our research to create red blood cells from human stem cells offers the prospect of limitless quantities of safe blood without the need for extensive donor programmes.

2) Pharmaceutical companies. Regenerative medicines provide a substantial potential market for Pharma companies in the UK and beyond - estimated to be at least $35bn by as soon as 2018.

Publications

10 25 50

 
Description RMEG membership
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
 
Description Visit Ian Murray MP
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Participation in a national consultation
Impact Part of a general objective of disseminating information concerning regenerative medicine, generating interest in this field.
 
Description MRC Centre Grant Renewal
Amount £2,055,900 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 05/2013 
End 04/2018
 
Description 13th European Symposium on Controlled Drug Delivery in Egmond aan Zee, The Netherlands 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Molly Stevens' opening lecture "Designing Nanomaterials for Biosensing", followed by discussion

"Bench to market" Knowledge exchange
Year(s) Of Engagement Activity 2014
URL http://www.escdd.eu/
 
Description 2014 MRS Spring Meeting and Exhibit, April 21-25 2014, San Francisco (California) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Molly Stevens acted as one of the meeting chairs. Diverse meeting topics ensured engagement of scientists and practitioners from different disciplines and backgrounds

Cross-disciplinary knowledge sharing
Year(s) Of Engagement Activity 2014
URL http://www.mrs.org/spring2014/
 
Description 2014 eCM XV: Cartilage & Disc: Repair and Regeneration. AO Research Institute, Davos (Switzerland) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Sue Kimber (keynote speaker): "Pluripotent Stem Cells for Cartilage repair", followed by discussion.

Scientists and clinicians together addressed the clinical challenges of articular cartilage and intervertebral disc repair
Year(s) Of Engagement Activity 2014
URL http://www.ecmjournal.org/ecm_meetings/ecm_15/
 
Description 2nd BIRAX Regenerative Medicine Conference, March 25-26 2014, Haifa, Israel 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professors Sue Kimber (Understanding chondrogenesis from pluripotent stem cells in vitro ) and Cay Kielty (Microenvironmental control of mesenchymal stromal cell fate) contributed to parallel sessions on 'Convergence of Cell and Gene Therapies' and 'Rejuvenation of endogenous stem cells', respectively.

The conference brought together leading scientists from the UK and Israel in the field of Regenerative Medicine to share latest developments in the field and to develop collaborations.
Year(s) Of Engagement Activity 2014
URL http://www.britishcouncil.org.il/en/2nd-BIRAX-conference
 
Description 3D Printing Ears 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact An interview and story on the BBC website about a collaborative project
Year(s) Of Engagement Activity 2017
URL http://www.bbc.co.uk/news/uk-scotland-edinburgh-east-fife-38152226
 
Description ASME 2014 3rd Global Congress on NanoEngineering for Medicine and Biology,Feb. 2-5, 2014, San Francisco, CA. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Molly Stevens keynote presentation "New Materials-Based Approaches for Regenerative Medicine"

Integration of Engineering, Materials Science, and Nanotechnology in addressing fundamental problems in Biology and Medicine and in developing devices, materials and methods for quantitative physiology and for the early detection, imaging of pathological and physiological mechanisms, and treatment of disease.
Year(s) Of Engagement Activity 2014
URL http://www.asmeconferences.org/nemb2014/
 
Description Advances and Applications of Functional Hepatocytes (AAFH) Symposium, Oct 29-30, 2014 Shanghai (China) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Dr. David Hay presented "Modelling Human Biology With Pluripotent Stem Cell Derived Hepatocytes"

The symposium brought research, industry and clinic together to update the latest achievements in sources and applications of hepatocyte-like cells, advancing goals of integrating latest technical progresses, bridging the demands from clinic and industry, and addressing some urgent problems in these areas
Year(s) Of Engagement Activity 2014
URL http://aafh.cscb.org.cn/
 
Description Ageing immune system may explain age-related cancer risk increase 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Ageing immune system may explain age-related cancer risk increase. Extensive coverage in the media.
Year(s) Of Engagement Activity 2017
URL https://www.dundee.ac.uk/news/2018/ageing-immune-system-may-explain-age-related-cancer-risk-increase...
 
Description Alzheimer's disease: An illness to forget a lifetime 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact 9 March 2016. Centre PhD Student Monica (Jee Soo) Kim took part in an afternoon activity for secondary school students at the Dundee Science Centre. S5/6 High School pupils with interest in studying science were invited to the event. Monica spoke to about 30 high school students and 5 teachers/non-students about her research, studying Biomedical Sciences , becoming a PhD student, conducting neuroscience research, multiple sclerosis and generally what it is like to be a scientist. Princess Anne also visited and Monica was able to talk to her about experience her research, and the importance of multiple sclerosis research in Scotland.
Year(s) Of Engagement Activity 2016
 
Description Anna Williams interview on Newsnight 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact 3,300 views on YouTube alone https://youtu.be/CC1FTyInECo (segment starts at 4:24)
Year(s) Of Engagement Activity 2018
URL https://youtu.be/CC1FTyInECo
 
Description Anna Williams interviewed on documentary for BBC Alba 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Anna Williams interviewed on documentary for BBC Alba. The story was also picked up in The Herald Scotland
Year(s) Of Engagement Activity 2018
URL http://www.heraldscotland.com/news/15796684.Stem_cells_help_mother_with_MS_make____remarkable____rec...
 
Description Art-sci exhibit 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Edinburgh College of Art final year students Sky Su, Ellen Adams and Beth Longmore met up with PhD students and Postdocs at CRM and developed artworks as part of their final portfolio, using scientific concepts and imagery. The project was part of the Edinburgh Neuroscience / Edinburgh College of Art FUSION project. Their work was displayed in the reception area of CRM and was part of their final exhibition at the ECA degree show. April - May 2015. Visitors CRM and art students / interested audience in art. Total visitor numbers unknown.
Year(s) Of Engagement Activity 2015
 
Description Artist in residence 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Hamer Dodds was given access to the building and various researchers engaged with him to provide inspiration and content for the production of artworks
Year(s) Of Engagement Activity 2015
 
Description BBC Radio 4 - The Life Scientific, Prof Sir Ian Wilmut 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Prof Sir Ian Wilmut was interviewed on BBC Radio 4 - The Life Scientific
Year(s) Of Engagement Activity 2016
URL http://www.bbc.co.uk/programmes/b07x2zct
 
Description Bile Duct Cancer Press Release 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact A limited media response to the press release (https://www.eurekalert.org/pub_releases/2016-10/uoe-bdc100716.php) and good engagement on social media notably by the AMMF (The Cholangiocarcinoma Charity).
Year(s) Of Engagement Activity 2016
URL http://www.ed.ac.uk/news/2016/bile-duct-study-uncovers-cancer-triggers
 
Description Brain Maze: Amaze Your Brain 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact MRC-CRM joined forces with the Centre for Cognitive Ageing and Cognitive Epidemiology to put on the interactive open day event as part of the MRC's Festival of Medical Research. The sell out event led people through the maze of corridors and rooms in the basement of the Department of Psychology, where CCACE is based. In each of the 11 rooms, they had 10 minutes to experience a different aspect of the ageing brain and body, three of the rooms covered aspects of CRM research: Thalamus, Multiple Sclerosis and an art installation by video artist Sky Su. The Maze finished with a cafe where participants got the chance to speak with scientists and reflect on their experience of the Maze. One of the main comments was that, having spent 2 hours in the maze chatting to scientists, people would have liked more time in each room.
Year(s) Of Engagement Activity 2016
URL https://youtu.be/apYmHzWO1So
 
Description Brain Study Paves Way for Dementia Therapy 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Press release and accompanying youtube video
University press release: https://www.ed.ac.uk/news/2018/drug-hope-for-dementia-and-stroke
Youtube video: https://youtu.be/QsUStmVuts0 303 Views
Facebook video https://www.facebook.com/CentreForRegenerativeMedicine/videos/1711118539006804/ 863 engagements 2,300 views
The story appeared in The Times, Scottish Daily Mail, Daily Mirror and Daily Express
https://www.express.co.uk/life-style/health/984079/drug-hope-dementia-stroke-victims-breakthrough-study
Broadcast: BBC Radio Scotland Newsdrive,
Online: The Times, Daily Express, Daily Mirror, New Atlas, Business Standard, UPI.com, Genetic Engineering & Biotechnology News, State Times (India), News-Medical.net, Siliconindia.com, India New England, New Kerala, Odisha Television Ltd., IANS (India), The Quint, Daily Pioneer, The New Indian Express, Dajiworld.com, Devdiscourse, India Today, European Scientist, NewsGram, Times Now News (India)
University social media: Neuro News Research Facebook Live broadcast (200 live views, 14k total), University video slideshow (Twitter: 101k reach, 188 clicks; Facebook: 6.1k views, 32 shares; LinkedIn: 84 likes)
Year(s) Of Engagement Activity 2018
URL http://www.crm.ed.ac.uk/news/brain-study-paves-way-dementia-therapy
 
Description Brownies activity at Macmerrry Primary School 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Kim Cuthbert (Roslin Cells Ltd) used our resources for a Group of Brownies, who were aged 7-9 years old at Macmerry Primary School. Floor game 'start as a stem cell' used as well as making a healthy cell from stem cells (playdoh activity). 11 children total, 26 May 2015.
Year(s) Of Engagement Activity 2015
 
Description Building The Extracellular Matrix: Molecules, Cells and Evolution. BSCMB Spring Meeting, April 7-8 2014, Bristol 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Cay Kielty presented ""Fibrillins and LTBPs: structural and growth factor regulatory roles"

The meeting focused on mechanisms and processes in Cell-ECM interactions and signaling, ECM structures and niches, and ECM-growth factor interactions.
Year(s) Of Engagement Activity 2014
URL http://www.bsmb.ac.uk/meetings-index/building-the-extracellular-matrix-molecules-cells-and-evolution...
 
Description CCBN Promotional Symposium 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Half day workshop/symposium held at UKRMP Niche Hub F2F meeting but opened up to external participants. Talks from academics using CCBN instrumentation.
Year(s) Of Engagement Activity 2015
 
Description CPD training day for teachers 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact 6 March 2014. Full day CPD training day for 32 Scottish secondary school Biology teachers at SCRM, in collaboration with SSERC. CRM team Involved: Prof Stuart Forbes, Prof Clare Blackburn, Prof Sir Ian Wilmut, Douglas Colby, Davina Wojtacha, Dr Gillian Morrison, Centre Manager Dr Gordon McLean, the outreach team (Cathy Southworth, Jan Barfoot, Katia Hervy, Ingrid Heersche), FACS Facilities managers Fiona Rossi and Claire Cryer demonstrated, and some junior researchers who showed their work on imaging microcopes: Dr Svetlana Ulyanchanka, Roly Megaw and Antoniana Batsivari. Day included scientific presentations, tour, lab techniques, ethics and looking at teaching resources. Teachers from 29 different schools all over Scotland (including from remote areas as far as Arran).


Part of a general objective of disseminating information concerning regenerative medicine, generating interest in this field.
Year(s) Of Engagement Activity 2014
 
Description CRM Facebook Account 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Facebook channel, >1,300 Likes to date
Year(s) Of Engagement Activity 2015,2016,2017
URL http://www.facebook.com/pg/CentreForRegenerativeMedicine
 
Description Cabaret of Dangerous Ideas Show: Eradicate Parkinsons (T Kunath) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact "Tilo Kunath and Parkinson's campaigner and sufferer John MacPhee put on the show Eradicate Parkinson's?! Part of the Cabaret of Dangerous Ideas at the Edinburgh Festival Fringe" Audience showed direct engagement through extensive questions and some audience members reported a change in views.
Year(s) Of Engagement Activity 2017
 
Description Café Scientifique 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact 9 December 2014. Dr Tilo Kunath gave an informal talk at a Café Scientifique event organised in Dunkeld. 26 people attended.
Year(s) Of Engagement Activity 2014
 
Description Café Scientifique 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact 9 December 2014. Dr Tilo Kunath gave an informal talk at a Café Scientifique event organised in Dunkeld. 26 people attended.
Year(s) Of Engagement Activity 2014
 
Description Cardinal Newman High School Visit 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Visit by 13 year old high school pupils who had taken part in the Brilliant Club. Talks about our work and tour of the Centre.
Year(s) Of Engagement Activity 2019
 
Description Castlebrae Community High School Workshops and visits 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Working in partnership with the local schools cluster we organise a programme of workshops with pupils, talks and visits to our facility.
Year(s) Of Engagement Activity 2018
 
Description Castlebrae School Mentorship 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Science Mentors@Castlebrae sees MRC CRM PhD students and postdoctoral scientists mentor Castlebrae Community High School senior pupils in science, technology and mathematics subjects.

Pupils report gaining confidence from their interactions with researchers.
Year(s) Of Engagement Activity 2018
URL http://www.crm.ed.ac.uk/community-science-engagement
 
Description Coming of Age - the legacy of Dolly at 20 Public Lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact On Thursday 1st September MRC-CRM Professor Emeritus Professor Sir Ian Wilmut (University of Edinburgh) spoke to a public audience with Professor Angelika Schnieke (Technical University Munich) and Nobel Prize Laureate Professor Shinya Yamanaka (Kyoto University). They discussed the impact of Dolly the Sheep on science, twenty years after her birth. Visitors heard inspiring talks about Dolly and cloning, stem cell research and the uses of genetically modified livestock and had a chance to put their questions to our prestigious panel. After the talks the discussions continued at our drinks reception, which included opportunities to talk to researchers from Centre.
Year(s) Of Engagement Activity 2016
URL http://dolly.roslin.ed.ac.uk/events-archive/coming-of-age-the-legacy-of-dolly-at-20-public-lecture/
 
Description Community Science Festival 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Now in its third year, the Craigmillar Community Science Festival is held on the last Friday in March in the run up to the Edinburgh International Science Festival. Held in partnership with The Community Alliance Trust at The White House Kitchen Community Cafe, the festival sees young people in the community demonstrating science to Festival-goers alongside scientists from the Centre and elsewhere at The University of Edinburgh.
Year(s) Of Engagement Activity 2018
 
Description Creating a New Gold Standard Model for Hepatotoxicity - A Pharma iQ Interview with David Hay 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Thought-provoking insights from leading Regen Med researcher

Increased interest/awareness in pharma community
Year(s) Of Engagement Activity 2014
URL http://www.pharma-iq.com/pre-clinical-discovery-and-development/articles/creating-a-new-gold-standar...
 
Description Dolly the Sheep: Major Discovery or Minor Distraction? 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Dolly the Sheep: Major Discovery or Minor Distraction? Thursday 25th August. CRM Researcher Dr Tilo Kunath, Cabaret of Dangerous Ideas, as part of Dollyat20 activity program, at the Fringe Festival in Edinburgh. Training ahead of time provided by Beltane. @CODIfringe. Public presentation with debate, discussion and engaging questions from the audience. A YouTube video summarises the event (https://youtu.be/LClmL5C9YJE) 50 views.
Year(s) Of Engagement Activity 2016
URL https://youtu.be/LClmL5C9YJE
 
Description Drummond Community High School Visit 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Visit by high school pupils: talks on science, careers in science and tours of the building.
Year(s) Of Engagement Activity 2018
 
Description Economist Article on Dolly the Sheep 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Interview with Professor Sir Ian Wilmut on the 20th Anniversary of the publication about Dolly the Sheep in Nature.
Year(s) Of Engagement Activity 2017
URL http://www.economist.com/news/briefing/21717028-twenty-years-ago-world-met-first-adult-clone-sheep-c...
 
Description Edinburgh College Visit 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Undergraduate students
Results and Impact Edinburgh College Visit involving staff and students. To engage in the science and talk about careers in science.
Very positive feedback, students changing their minds about a career in science
Year(s) Of Engagement Activity 2017
 
Description Edinburgh College Visit 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact A visit by 30 students from Edinburgh College (adult learners, doing a biology conversion course to go on to University study), with an introduction to Stem Cells and some of the work in the Centre, a lab tour and discussion about different careers in science.
Year(s) Of Engagement Activity 2017
 
Description Edinburgh International Science Festival 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact 14-18 April 2015. CRM PhD students Eleni Karigianni, Julia Watson and Antoniana Batsivari developed a new 'Making Stem Cells for Mr Skeleton activity. Eight other students involved in demonstrating at the festival. As part of the University's Discover Science Program at the Museum of Scotland. 1940 audience
Year(s) Of Engagement Activity 2015
 
Description Edinburgh International Science Festival 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Interactive exhibit as part of the College of Medicine and Vet Medicine Family drop-in session at the Edinburgh International Science Festival.
Year(s) Of Engagement Activity 2018
 
Description Edinburgh Science Festival Discussion Forum 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact DOLLY AND ME... 20 YEARS WITH THE WORLD'S MOST FAMOUS SHEEP: 2016 marks the 20th anniversary of the birth of Dolly the Sheep, the first mammal to be cloned from an adult cell. Prof Sir Ian Wilmut, who led the research which created Dolly, and our other expert panellists took questions and revealed what working with the world's most famous sheep meant to them. They described the impact did she had on those closest to her and how Dolly still influences cutting-edge scientific research in Edinburgh and beyond.
Year(s) Of Engagement Activity 2016
 
Description Edinburgh Science Festival talk: "From bench to bedside and beyond" 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Well attended event organised by Edinburgh BioQuarter and involving Prof Anna Williams and Dr Tilo KUNATH both of whom appeared in a promotional video for BioQuarter follwing the event (296 views) https://youtu.be/Z_WKtph8zbQ
Year(s) Of Engagement Activity 2018
URL https://youtu.be/_yMvqSSAO6k
 
Description EuroStemCell.org project - update 2014 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact The eurostemcell.org website has had 1,194,812 unique page views during 1 Nov 2013 - 1 Nov 2014. CRM hosts this site, many scientists contribute content (review factsheets, write blogposts, develop outreach materials, translate content into other European languages, etc. Specific events have been organised as well, school's workshops etc. Specific highlights this year: release of a new 28min film documentary 'Cell Fate', contribution to European Researchers Night in Edinburgh (Explorathon), and contribution & expert advice to 'Super Cells', a major stem cell exhibit developed by the Canadian Stem Cell Network, which will tour around the world in 2015 and 2016.


Part of a general objective of disseminating information concerning regenerative medicine, generating interest in this field.
Year(s) Of Engagement Activity 2014
URL http://www.eurostemcell.org
 
Description Exhibit stand BSGCT public engagement day 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact 09 May 2015. Public engagement day for lay adult audience and secondary school students, Glasgow. As part of the British Society for Gene and Cell Therapy annual conference. PhD students Antoniana Batsivari, Julia Watson and Eleni Karagianni adapted a new activity for use with an adult audience and secondary school students. Audience were making cells from household materials to 'regenerate' DrSkelfie, a skeleton suffering from various illnesses. Also included a picnic basket for feeding cells in the lab, as part of the mobile 'stem cell lab'. 100 audience.
Year(s) Of Engagement Activity 2015
 
Description Exhibit tent Greenman Festival 'Dr Skelfie and the Stem Cell team' 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact A team of six scientists from the MRC Centre for Regenerative Medicine travelled down to Wales in August 2015 to take part in the Greenman Festival. The three day cultural festival is aimed at families and young adults. A dedicated area, Einstein's Garden, offers visitors the unique opportunity to brush up their science and engage with researchers from many different areas. Despite the bad weather, our team of stem cell specialists engaged with 1,500+ visitors. Using a newly developed 'Dr Skelfie and the Stem Cell Team' exhibit people were encouraged to make nerve cells for DrSkelfie, a skeleton, in the 'stem cell lab' using sim cards, electrical wiring and insulation tape. The conversation starter activity naturally led to further deep level engagement with many visitors. In addition to the exhibit, we also took part in the Human Library project and developed a Stem Cell Ceilidh dance for the science ceilidh band. Part of the display work was developed by Edinburgh College of Art student Ellen Adams. The exhibit was developed by PhD students Eleni Karagianni, Julia Watson and Antoniana Batsivari. Other team members included PhD student Dan Kaemena, Postdoc Nicholas Tan and CRM Communications Manager Ingrid Heersche.
Year(s) Of Engagement Activity 2015
 
Description Filmosophy: regeneration 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact "4 Film screenings followed by informal discussions at the Edinburgh Filmhouse. Each evening session captured between 40-90 visitors. CRM Senior Scientists took part: Charles ffrench-Constant, Ian Wilmut, Clare Blackburn and Donal O'Carroll. During the first month, CRM Artist in residence Hamer Dodds put up scientific imagery and artworks in the Edinburgh Filmhouse. More information about the events:
A new series of thought-provoking cinema screenings, which probe into issues surrounding regenerative medicine, will take place in Edinburgh this autumn.
The Filmosophy: Regeneration season will put a spotlight on ethical topics raised in the films shown - such as the use of stem cells and genetic modification - during post-screening discussions with experts from the University of Edinburgh.
The series takes place at Edinburgh's Filmhouse from 8 September until 8 December, and is delivered in association with Short Courses at the University of Edinburgh and the MRC Centre for Regenerative Medicine.
The season begins on Tuesday 8 September with Never Let Me Go, based on Kazuo Ishiguro's best-selling novel, it is a story of love and loss that deals with the ethics of human cloning for medical purposes. Professor Charles ffrench-Constant, Director of the MRC Centre for Regenerative Medicine, will take part in the post-screening discussion.
The critically-acclaimed I Am Breathing, which follows the story of Motor Neuron Disease-sufferer Neil Platt during the last few months of his life, will be shown in October. The film was co-directed by Emma Davie, Programme Director of Film and TV at Edinburgh College of Art and Morag McKinnon and was produced by Sonja Henrici of the Scottish Documentary Institute.
Further screenings include Darren Aronofsky's The Fountain, featuring three intertwining tales about men in pursuit of eternal life, and Pedro Almodovar's The Skin I Live In, a warped and creepy revenge thriller in which a plastic surgeon (Antonio Banderas) is obsessed with his latest revolutionary skin treatment.
James Mooney, Lecturer in Film and Philosophy at the University of Edinburgh, said: "We are delighted to partner with the CRM to curate this original programme. As well as offering a fresh perspective on the films, it is an opportunity to showcase some of the ground-breaking research taking place in Edinburgh right now. The scientists involved in the discussions are world-leaders in their field, and I am looking forward to what should be a stimulating and powerful debate on the ethics of stem cell research."
Artwork by Hamer Dodds, artist-in-residence for the Centre for Regenerative Medicine, will accompany the Regeneration season. His exhibition of microscopic cell images and drawings are on show at the Edinburgh Filmhouse throughout September.
Regeneration programme:
• Tuesday 8 September: Never Let Me Go (Romanek 2010)
• Tuesday 13 October: I Am Breathing (Davie and McKinnon 2013)
• Tuesday 10 November: The Fountain (Aronofsky 2006)
• Tuesday 8 December: The Skin I Live In (Almodovar 2011)
Tickets cost £9 and can be booked online: http://www.filmhousecinema.com/seasons/filmosophy-regeneration-sep15/. Buy any three (or more) tickets for films in this season and get 15% off.
For more information on Filmosophy, visit www.facebook.com/thinkingfilm or www.twitter.com/film_philosophy.
"
Year(s) Of Engagement Activity 2015
 
Description Finnish Biotechnology Student Society Biopsi (University of Tampere) Visit 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Undergraduate students
Results and Impact Finnish Biotechnology Student Society Biopsi (University of Tampere) visit: talks about the Centre science, science careers and facilities/lab tours
Year(s) Of Engagement Activity 2017
 
Description French High School Visit 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Schools
Results and Impact Talks about our science, research, careers in science and tour of the building and facilities.
Year(s) Of Engagement Activity 2018
 
Description Full day SSERC CPD training session 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact 27 March 2015. Full day CPD training for 16 Scottish Secondary School Biology Teachers from 16 different schools. In collaboration with SSERC. Comms team and some students also involved. Gillian Morrison gave a presentation about Diabetes and stem cells. Day also involved hands-on sessions on stem cell ethics (with Ian Wilmut and Jan Barfoot), looking at educational resources (Cathy Southworth) a tour around the facilities (Gordon McLean) and Imaging FACS (Bertrand Vernay). All teachers were given a take-away kit with the DVDs (Stem Cell Revolutions), board game 'start as a stem cell', 'All about Stem Cells' activity, and a classroom set of Hope Beyond Hype with instructions and a teratoma microscopy slide.
Year(s) Of Engagement Activity 2015
 
Description Gordon Research Conference • Biointerface Science, Il Ciocco, Italy, 15-20 June 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Molly Stevens presentation and discussion "Investigating and Engineering the Cell-Material Interface"

New insights shared among practitioners
Year(s) Of Engagement Activity 2014
URL http://www.grc.org/programs.aspx?year=2014&program=biointerf
 
Description Gordon Research Conference: Signaling by Adhesion Receptors, June 22-27 2014, Maine (USA) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Cay Kielty presentation "Microenvironmental Regulation of Mesenchymal Stem Cell Fate" , followed by discussion

Sharing new unpublished findings on adhesion signaling in all of the most actively researched topic areas
Year(s) Of Engagement Activity 2014
URL http://www.grc.org/programs.aspx?year=2014&program=sigadhes
 
Description Ground Breaking and press for new Centre for Tissue Repair 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact A ground breaking ceremony for the new Centre for Tissue Repair for key internal and external stakeholders and local press interest: Article in the Edinburgh Evening News https://www.edinburghnews.scotsman.com/news/health/edinburgh-centre-offers-new-hope-on-incurable-disease-1-4594637
Year(s) Of Engagement Activity 2017
URL https://www.edinburghnews.scotsman.com/news/health/edinburgh-centre-offers-new-hope-on-incurable-dis...
 
Description Hope Beyond Hype II: Scottish Stem Cell Stories 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Hope Beyond Hype II: Scottish Stem Cell Stories project (Sept 2013 - Nov 2014). Funded by the Scottish Government (£40k), the MRC (£3k), and CRM (£3k), with in kind contributions from other universities and patient charities (MS Society). TOTAL engagement with 14,599 people. In total 7 Festivals (7857 people), 12 patient (581 people) and 13 local community events (3053 people) in remote areas of Scotland. All festivals run by communications team at CRM (including Ingrid Heersche), with many contributions by MRC funded PhD students from CRM. Social Media output: 20 Facebook posts with combined reach of 734 audience and 65 tweets. The website http://www.eurostemcell.org/hope-beyond-hype-scottish-stem-cell-stories had 480 views, other content was developed: Scottish Stem Cell Stories (363 unique page views), sporty stem cell animates (177 unique page views), Sports Medicine research overview (561 unique page views), total views: 1581. Animates on YouTube had 793 views (15 Aug 2014 - 05 November 2014).


Part of a general objective of disseminating information concerning regenerative medicine, generating interest in this field.
Year(s) Of Engagement Activity 2014
URL http://www.eurostemcell.org/hope-beyond-hype-scottish-stem-cell-stories
 
Description Hydra XIII Summer School - Best practice in science communication and public engagement 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Hydra XIII Summer School - Best practice in science communication and public engagement. Sharing best practice in science communication and public engagement
Year(s) Of Engagement Activity 2017
 
Description ISSCR 12th Annual Meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Several UKRMP Niche Hub PIs participated / presented at this major conference. Meeting Program Committee chaired by Professor Fiona Watt

Knowledge sharing among practitioners of stem cell and regenerative medicine research
Year(s) Of Engagement Activity 2014
URL http://www.isscr.org/home/annual-meeting/2014annualmeeting/recap
 
Description Invited talk 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other audiences
Results and Impact 20 March 2015. Jane Taylor was invited to talk about stem cells and regenerative medicine. "The secretary of the Edinburgh Medico-Chirurgical Society (http://www.edmedchi.co.uk ) wrote to me after the May 2014 stem cell summer school we held for GPs and clinicians (Stem Cells and Regenerative Medicine: Current Status and Future Prospects) inviting me to talk to their members about stem cells and regenerative medicine. The Edinburgh Med Chi is an old society (founded in 1821) which meets monthly during the University term time for lectures and occasional formal dinners. Their members are drawn from all medical specialities (eg physicians, cardiac surgeons, psychiatrists and GPs) and quite a number are retired. One of the members had attended our meeting and said it was a 'most inspiring and enjoyable meeting - the best he had been for ages' and he had recommended my introductory talk for the EdMedChi programme. The meeting was arranged for Fri 20 March at 7.30pm (held at Lifecare, Stockbridge House, Edinburgh) - there were about 30 members present and I spoke for 30 mins with a Q and A session afterwards. There was a very lively discussion at the end with lots of questions. I gave them the Eurostemcell web address and the CRM address for further information."
Year(s) Of Engagement Activity 2015
 
Description Invited talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact 20 March 2015. Jane Taylor was invited to talk about stem cells and regenerative medicine. "The secretary of the Edinburgh Medico-Chirurgical Society (http://www.edmedchi.co.uk ) wrote to me after the May 2014 stem cell summer school we held for GPs and clinicians (Stem Cells and Regenerative Medicine: Current Status and Future Prospects) inviting me to talk to their members about stem cells and regenerative medicine. The Edinburgh Med Chi is an old society (founded in 1821) which meets monthly during the University term time for lectures and occasional formal dinners. Their members are drawn from all medical specialities (eg physicians, cardiac surgeons, psychiatrists and GPs) and quite a number are retired. One of the members had attended our meeting and said it was a 'most inspiring and enjoyable meeting - the best he had been for ages' and he had recommended my introductory talk for the EdMedChi programme. The meeting was arranged for Fri 20 March at 7.30pm (held at Lifecare, Stockbridge House, Edinburgh) - there were about 30 members present and I spoke for 30 mins with a Q and A session afterwards. There was a very lively discussion at the end with lots of questions. I gave them the Eurostemcell web address and the CRM address for further information."
Year(s) Of Engagement Activity 2015
 
Description Let's Talk About Health: Multiple Sclerosis: success, challenges and hope 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact 17 February 2016. Let's Talk About Health: Multiple Sclerosis: success, challenges and hope. Let's Talk series. Dr Anna Williams presented a public talk on Multiple Sclerosis, the challenges that have been overcome, the challenges that remain, and the exciting research that is taking place that offers hope for treatment of this disease.
Year(s) Of Engagement Activity 2016
 
Description Liver success holds promise of 3D organ printing article in the FT 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact CRM Director Stuart Forbes and Group Leader Prof Dave Hay interviewed for the in the Financial Times Special Report 50 Ideas to Change the World
Year(s) Of Engagement Activity 2017
URL https://www.ft.com/content/67e3ab88-f56f-11e7-a4c9-bbdefa4f210b
 
Description Local Community Science Festival 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Community Science Festival - Engaging local families in the science of the Centre. Activities co-created with local secondary school pupils. Activity led by Engagement Manager Dr Cathy Southworth. The Community Science Festival provided an opportunity for the external evaluator to capture feedback via snapshot interviews with 6 secondary pupils about their experiences of activities that have been delivered as part of the Science Development Project, including the Festival itself. Pupils were asked how these activities made them feel about science and school. All responses were positive and fell into two main categories:
• Greater enjoyment at doing 'real' science and using equipment and techniques that were new to them
• Pride at being selected to take part in the Community Science Festival and being able to present their work to their families and others
Pupils indicated that the activities they had undertaken to prepare for the Science Festival were more enjoyable than regular science lessons, which they attributed the practical nature of those activities, the interesting techniques or equipment they used and the 'real-life' relevance of the science.
Making the smartphone microscope was really cool. I'd never done anything like it before. (Pupil)
I liked finding out different ways you could use it [smartphone microscope] to do different experiments. Experiments are the best thing in science. (Pupil)
This is what real scientists do which is cool. It is complicated but better than being boring. (Pupil)
Feedback was captured from 16 parents/carers or extended family members who attended the Community Science Festival. They included individuals with children at a local nursery school as well as those with connections to pupils at Castlebrae and Castleview schools.
Interviewees were told the Festival was part of the Castlebrae Cluster Science Development Project and asked what they thought of the concept of the Project and how it and/or the Festival made them feel about science, local schools and their own community.
Views about the Science Development Project
All interviewees welcomed the idea of a project to promote science, which they felt was an increasingly important subject for young people. Some commented that historically Castlebrae school has not had a strong reputation for science, which they thought the Project could help to address.
I think it's brilliant. The Edinburgh Science Festival is too pricey so having science in Niddrie is really good especially as science is so important today with technology being in everything. (Parent/carer)
If it is all like this [the Science Festival] which has been put together very well, then I think it is a very good idea. It can only help the school, which is trying to change its image. (Parent/carer)
I don't think I've ever associated Castlebrae with science, but today is changing my view. (Parent/carer)
Year(s) Of Engagement Activity 2017
 
Description MBE (Matrix Biology Europe) conference 21 - 24 June 2014, Rotterdam (Netherlands) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor cay Kielty presentation "The effect of fibrillin mutations: Altered TGF-beta and heparin binding results in a variety of connective tissue diseases" in workshop on 'advances in understanding matrix disease mechanisms'.

Senior and young scientists and scholars participated in order to:
- Communicate the results of their recent research
- Experience research presentations across the broad spectrum of matrix biology
- Exchange ideas and to argue alternate interpretations through informal discussion
- Establish friendships and renew old friendships
Year(s) Of Engagement Activity 2014
URL http://www.mbe2014.eu/home
 
Description MP Visit - Tommy Sheppard MP 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact "Introduction to the Centre (both the science and community engagement) and the Medical Research Council. Discussions re scientific excellence, employment, community engagement, effect of Brexit etc. Mr Sheappard said on Facebook ""I was incredibly impressed by my visit to the MRC Centre for Regenerative Medicine in Edinburgh's Bioquarter. Hundreds of scientists from across the globe developing truly world leading research in stem cells and regeneration. Clinical treatment is at the forefront - developing treatments to some of Scotland's most challenging diseases including liver disease, MS and MND.
And they have an excellent outreach and community engagement programme, particularly with Castlebrae CHS. Nathana and Jayanti came along from the school to tell me about the mentors who visit Castlebrae and support pupils with their science coursework and the summer internship programme in the centre.
Thanks to all the team for taking time out to show me round - I'm already looking forward to a future visit as the new facility to house a Centre for Tissue Regeneration and Repair takes shape.""" Impact from this was - Posts on social media (72 reactions on MPs Facebook page)
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/TommySheppardSNP/posts/1934307746817282
 
Description MRC Festival of Medical Sciences 25th June 2018 - CRMat10 Event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Supporters
Results and Impact A reception to celebrate 10 years of the Centre. Presenters included directors, staff, students and community partners. It was attended by a long standing donor of the Centre, one of the first PhD students and our local community school partners. Awards recognised significant contributions to the MRC CRM over the past 10 years and included past and present members of the professional services team. Staff commented that they found the event inspiring and appreciated its inclusiveness. The event generated a lot of interest on social media
160 Engagements for one Twitter post https://twitter.com/crm_edinburgh/status/1010208591712870401
204 Engagements for one Facebook post https://www.facebook.com/CentreForRegenerativeMedicine/posts/1691853487599976
This is well above average for our social media channel and among the top 3 posts in the year.
Year(s) Of Engagement Activity 2018
URL http://www.crm.ed.ac.uk/CRMat10awards
 
Description MRC Insight blog "Taking science into school: why both sides benefit" 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Blog by PhD student Colin Plumb on MRC Instight talking about the Centre School Pupil Mentoring programme. 1,229 impressions on MRC-CRM Twitter.
Year(s) Of Engagement Activity 2017
URL https://www.insight.mrc.ac.uk/2018/02/15/taking-science-into-school-why-both-sides-benefit/
 
Description MRC Millenium Medial Science Showcase at the UK Parliament 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Prof Stuart Forbes represented the Centre at the MRC Millenium Medial Science Showcase at the UK Parliament. "Feedback on the way out was incredibly positive, saying how much they had enjoyed the research you exhibited and how useful and interesting they had found the conversations that followed." - Katy Ingleby, MRC
Year(s) Of Engagement Activity 2017
URL https://twitter.com/The_MRC/status/956228871006965760
 
Description MRC Research Showcase at the Scottish Parliament 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact MRC Research Showcase at the Scottish Parliament highlighting biomedical research within Scottish Universities funded by the MRC.Professor Hay reported that he will have followup discussions with Miles Briggs MSP about health policy.
Year(s) Of Engagement Activity 2018
URL https://twitter.com/crm_edinburgh/status/1093224653341057025
 
Description Midlothian Sci Festival Event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Midlothian Sci Festival Event: family focussed drop in activities focussed on Zebrafish.
Year(s) Of Engagement Activity 2017
 
Description New Collaboration to Accelerate Drug Discovery Using Stem Cell Technology 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact A press release with the University of Dundee National Phenotypic Screening Centre (NPSC)
marking the signing of a Memorandum of Understanding with the Centre "that commits them to work more closely together as they strive to translate novel biological discoveries into new stem cell therapies".
Year(s) Of Engagement Activity 2017
URL http://www.drugdiscoverytoday.com/view/45514/scottish-universities-collaborate-to-accelerate-drug-di...
 
Description New discovery speeds cell reprogramming in the lab - from Keisuke Kaji and colleagues. 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact "New discovery speeds cell reprogramming in the lab - from Keisuke Kaji and colleagues.". There was interest in the story on social media.
Year(s) Of Engagement Activity 2017
URL https://www.ed.ac.uk/news/2017/quest-for-new-drugs-could-be-helped-by-cell-discov
 
Description Niddrie Primary School Science Club 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Regular science club for primary pupils.
Pupils from all three primary schools highlighted how programmes of activities, such as science clubs, increased their confidence in their own abilities to study and enjoy science.
Year(s) Of Engagement Activity 2018
 
Description Operetta Image and Data Analysis Training 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Operetta Image and Data Analysis Training
Year(s) Of Engagement Activity 2016
 
Description Operetta Training 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Training session on Operetta
Year(s) Of Engagement Activity 2016
 
Description Paris High School Visit 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Schools
Results and Impact French School Visit. Talks about science and careers in science. Positive feedback.
Year(s) Of Engagement Activity 2017
 
Description Patient enquiries 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Patients, carers and/or patient groups
Results and Impact Personalised emails asking for help, guidance and advice re latest research on regenerative medicine, clinical trails and pursuing treatments offered by private clinics.
Year(s) Of Engagement Activity 2015
 
Description Patient enquiries 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Patients, carers and/or patient groups
Results and Impact Personalised emails asking for help, guidance and advice re latest research on regenerative medicine, clinical trails and pursuing treatments offered by private clinics.
Year(s) Of Engagement Activity 2014
 
Description Patient enquiries 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Personalised emails asking for help, guidance and advice re latest research on regenerative medicine, clinical trails and pursuing treatments offered by private clinics.
Year(s) Of Engagement Activity 2014
 
Description Population Health Directorate, Scottish Government Talks and Tours 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Policymakers/politicians
Results and Impact CPD for Scottish Government employees. They heard an overview of the Centre and a cross-section of its science with a focus on public health issues. Tour of facilities.
Positive feedback, participants felt informed and inspired.
Year(s) Of Engagement Activity 2017
 
Description Portraits of the Brain - workshop for people living with MS (patients) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Patients, carers and/or patient groups
Results and Impact A series of workshops in which people living with MS interacted with researchers studying MS. Informal discussion was facilitated by mutual working on producing art.
Very positive response from patients and MS researers
Feedback from participants:
"Even scientists are unsure how the body works. Nice to find this out- makes scientists people.''
''I've never really spoken to a researcher before and it's so great that there is a human on the other side!''
''I enjoyed having a relaxing chat about my illness''
'' I enjoyed the distraction/ opportunity to do something therapeutic I enjoyed being distracted so my hand tremors stopped! Being able to paint on the lines is something I'm not normally able to do! ''
'' I learned that I do have a positive outlook despite having MS for years ''
'' I learned to relax talking about my illness on a different level, having someone interested and able to understand how MS affects my life ''
'' I loved the experience. This intimate, informal, way of talking, learning one to one with 'my' paired researcher was totally helpful and meaningful ''
'' I learned about how oligodendrocytes grow and form and I thought that was really interesting ''
'' It has given me a perception of complexity of disease and difficulties of research and why we aren't seeing treatments develop immediately! I have a great respect for the ongoing work''
'' Good to find out that scientists uncertainty is driving them to discover more''
'' It has given me a thirst to learn more alongside scientists- Collaboration!''
'' Love it! Was an incredible experience ''
'' Comfortable, any anxiety quickly disappeared! The introduction set the scene very well and made us all seem on the same level!''
'' Inspiring- I would like more time with scientists. Collaboration. Art + Science''
'' Don't stop offering exactly this style of in depth and creative knowledge exchange''
'' Seems like this kind of event could be extremely useful for both parties. Should expand and continue!''
' Great opportunity to meet other people living with MS, more importantly excellent to be able to meet researchers! The way this has been done with a creative task helped create relaxing atmosphere and actually talking while painting took my mind off the painting and my hand tremors completely stopped so I am very happy to have been able to paint in the lines! ''
'' It was good to paint while chatting as I forgot who was the scientist and who was the MS sufferer''
Year(s) Of Engagement Activity 2018
URL http://www.crm.ed.ac.uk/seminars/portraits-brain
 
Description Press Release - Cigarette study suggests damage to unborn children 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Press release https://www.ed.ac.uk/news/2017/cigarette-harm-to-unborn-children-revealed. Coverage on BBC Online: http://www.bbc.co.uk/news/uk-scotland-40084844
Year(s) Of Engagement Activity 2017
URL http://www.bbc.co.uk/news/uk-scotland-40084844
 
Description Press Release: Blood study may improve stem cell 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact https://www.ed.ac.uk/news/2017/blood-study-stem-cell-therapy
Year(s) Of Engagement Activity 2017
URL https://www.ed.ac.uk/news/2017/blood-study-stem-cell-therapy
 
Description Press coverage New Centre for Tissue Repair 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact "Press release 25 March 2015, Charles ffrench-Constant and Stuart Forbes. Announcement 10.7M for Centre for Tissue Repair. THE HERALD, THE SCOTSMAN, DAILY RECORD, EDINBURGH EVENING NEWS, PRESS AND JOURNAL, THE NATIONAL. Edinburgh secures £25.7m in Government funding to build powerhouse of biological and medical research.
"
Year(s) Of Engagement Activity 2015
 
Description Press coverage Prof Clare Blackburn paper 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact 08 April 2014. Press coverage Clare Blackburn's research as published in Development. Press release by MRC. Living organ regeneration 'first' by gene manipulation (BBC News)
http://www.bbc.co.uk/news/health-26920528

Breakthrough as scientists regenerate an animal's organ for the first time (Daily Mail)
http://www.dailymail.co.uk/health/article-2599755/Breakthrough-scientists-regenerate-animals-organ-time-paving-way-organ-restoration-humans.html#ixzz2yNrIO9fp

Engage reverse gear (The Economist)
http://www.economist.com/news/science-and-technology/21600356-first-time-mammalian-organ-has-been-persuaded-renew-itself-engage

Scottish scientist's success in organ regeneration (Scotsman)
http://www.scotsman.com/news/health/scottish-scientist-s-success-in-organ-regeneration-1-3369626

SCIENTISTS REGENERATE ORGAN IN MICE, DEFYING AGE EFFECTS (Al Jazeera America)
http://america.aljazeera.com/articles/2014/4/8/scientists-mice-regenerate.html

Breakthrough in organ renewal (Herald)
http://www.heraldscotland.com/news/home-news/breakthrough-in-organ-renewal.23916925?utm_source=www.heraldscotland.com&utm_medium=RSS%20Feed&utm_campaign=Scottish%20News

Scientists succeed in restoring organ for first time (Irish Independent)
http://www.independent.ie/lifestyle/health/scientists-succeed-in-restoring-organ-for-first-time-30168240.html

Edinburgh scientists 'reverse ageing' in mice (Edinburgh Evening News)
http://www.edinburghnews.scotsman.com/news/edinburgh-scientists-reverse-ageing-in-mice-1-3370150

Other online

Medical Express: http://medicalxpress.com/news/2014-04-regenerated.html
Medical Daily: http://www.medicaldaily.com/regenerative-medicine-breakthrough-sees-scientists-rebuilding-immune-organ-275376
Tech Times: http://www.techtimes.com/articles/5362/20140409/humans-to-immortals-scientists-successfully-perform-gene-manipulation-to-regenerate-old-organs.htm
Press TV: http://www.presstv.ir/detail/2014/04/09/357795/breakthrough-in-regenerative-medicine/
PHG Foundation: http://www.phgfoundation.org/news/15852/
Medical News Today: http://www.medicalnewstoday.com/articles/275204.php
Business Day Live: http://www.bdlive.co.za/life/health/2014/04/09/medical-boost-for-elderly-mice-humans
Fast Company: http://www.fastcompany.com/3028832/fast-feed/fountain-of-youth-scientists-regenerate-damaged-organ-in-a-mammal-for-first-time-e
Healthcare Today: http://www.healthcare-today.co.uk/news/uk-scientists-manipulate-dna-to-regenerate-living-organ/25373/
Business Standard: http://www.business-standard.com/article/pti-stories/living-organ-regenerated-for-first-time-114040900652_1.html
Business Insider: http://www.businessinsider.com/r-scientists-regenerate-immune-organ-in-mice-2014-08
HNGN: http://www.hngn.com/articles/28412/20140408/thymus-regenerated-in-genetically-modified-mice-for-the-first-time-organ-resembled-youths.htm
Science Daily: http://www.sciencedaily.com/releases/2014/04/140408115610.htm
GMA News: http://www.gmanetwork.com/news/story/356096/scitech/science/scientists-regenerate-immune-organ-in-mice
The Financial Express: http://www.financialexpress.com/news/living-organ-regenerated-for-first-time/1239431
The Nation: http://www.nation.com.pk/snippets/09-Apr-2014/scientists-regenerate-immune-organ-in-mice
News Daily: http://www.newsdaily.com/health/b78e9f396231a281e620ba1cb9c900a5/scientists-regenerate-thymus-in-mice
Also in DAILY THE PAK BANKER (Pakistan), GLOBEDIA, LA BRUJULA VERDE (Spain), FINANCIAL EXPRESS (India), PHYS ORG, MEDICAL DESIGN ONLINE (USA), LE NOUVAL OBSERVATEUR (France), NANYANG SIAN PAU, HUAXIA, CHINA SCIENCE AND TECHNOLOGY NET, CHINA PHARMACEUTICAL NEWS (China) Edinburgh team led by Clare Blackburn successfully regenerates organ in mouse

To date the YouTube film accompanying the release (http://youtu.be/wcc0eVoubEk) has been viewed 11,256 times.


Part of a general objective of disseminating information concerning regenerative medicine, generating interest in this field.
Year(s) Of Engagement Activity 2014
URL http://www.crm.ed.ac.uk/news/fully-functional-immune-organ-grown-mice-lab-created-cells
 
Description Press coverage Stuart Forbes 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Press release 17 Feb 2015, Stuart Forbes. The study, published in the Journal of Clinical Investigation on 17 February 2015, suggests experimental drugs targeting the wnt pathway might help patients with cholangiocarcinoma. Press release: http://ow.ly/JffeA. Various press coverage including STV News online (http://bit.ly/1MUsNhQ) and Herald Scotland (http://bit.ly/1DdK51v).
Year(s) Of Engagement Activity 2014
 
Description Press coverage Stuart Forbes 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Press release 17 Feb 2015, Stuart Forbes. The study, published in the Journal of Clinical Investigation on 17 February 2015, suggests experimental drugs targeting the wnt pathway might help patients with cholangiocarcinoma. Press release: http://ow.ly/JffeA. Various press coverage including STV News online (http://bit.ly/1MUsNhQ) and Herald Scotland (http://bit.ly/1DdK51v).
Year(s) Of Engagement Activity 2015
 
Description Press release (MRC) 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Press release via MRC, 20 July 2015. Stuart Forbes and colleagues had a paper published in Nature Cell Biology yesterday. They have successfully repaired a damaged liver in a living mouse for the first time, using stem cells. We worked closely with the MRC press office to prepare a press release about the findings. Ingrid has also prepared a separate section of the website with patient information to help manage any enquiries. Please find below a summary of press coverage for the study. Print articles about the research appeared today in Daily Express, Daily Mirror, Metro, Herald Scotland and Daily Record (clippings attached). There are online articles on BBC Health, Mirror, Herald, and BBC Scotland. Stuart spoke to BBC Good Morning Scotland about the research this morning too (~2h51m): http://www.bbc.co.uk/programmes/b062n0l7#play.
Year(s) Of Engagement Activity 2015
 
Description Press release: Brain cancer study reveals therapy clues 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact https://www.ed.ac.uk/news/2017/brain-cancer-study-reveals-therapy-clues
Year(s) Of Engagement Activity 2017
URL https://www.ed.ac.uk/news/2017/brain-cancer-study-reveals-therapy-clues
 
Description Press release: Stem cell liver implants show promise 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Press release from CRM resulting in media coverage on websites and in newspapers.
Scottish Daily Mail
https://www.pressreader.com/uk/scottish-daily-mail/20180828/281977493484972
Online
https://www.fiercebiotech.com/research/growing-human-stem-cells-into-functional-3d-liver-tissue
https://www.rdmag.com/article/2018/08/new-liver-tissue-implants-showing-promise
MRC website
https://mrc.ukri.org/news/browse/liver-tissue-implants-show-promising-support-of-liver-function/
Year(s) Of Engagement Activity 2018
URL http://www.crm.ed.ac.uk/news/stem-cell-liver-implants-show-promise
 
Description Primary Science Workshop, Cathy Southworth 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Engaging local primary school teachers in science and tours of the Centre by staff. Primary Science Workshop led by Dr Cathy Southworth, Public Engagement Manager
Year(s) Of Engagement Activity 2017
 
Description Primary school visit 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact 25 May 2015. Joint activiy with IGMM at James Gillespie Primary School, two 1hr sessions, both p5 (class of 25 kids and one 29 kids, age 9/10yrs old. 4 different stations: making cells in the mobile stem cell lab for DrSkelfie, making healthy cells using playdoh, looking at your own scabs & skin with microscope, drawing cells by looking at them under a microscope. CRM Postdoc Melany Jackson involved as well as Rebecca Scott (PE coordinator IGMM).
Year(s) Of Engagement Activity 2015
 
Description Prof. Molly Stevens Plenary lecture Nanobio Australia 2014 (Brisbane) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact NanoBio Australia 2014 featured a diverse array of multi-disciplinary science designed to connect world-leading scientists, engineers and entrepreneurs working in this space.

expansion / enhancement of knowledge networks
Year(s) Of Engagement Activity 2014
URL http://www.icbni.com.au/
 
Description Professor Fiona Watt's contribution to the promotion of Stem Cell and Regenerative Medicine research 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Wide dissemination of knowledge and understanding of stem cell and regenerative medicine research

KCL award for "Most Outstanding Contribution to Public Engagement"
Year(s) Of Engagement Activity 2014
URL http://www.wattlab.org/news-archive.html
 
Description Public Lecture Dr Tilo Kunath 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Undergraduate students
Results and Impact Public Lecture - Stem Cells & Parkinson's Disease. Lecture in series of Edinburgh University Science Magazine (EUSci) will be given by Dr Tilo Kunath on Parkinson's disease and stem cells on 4th May 2015 at 7:30pm. Old College, Edinburgh. 14 people attended.
Year(s) Of Engagement Activity 2015
 
Description Public engagement training for researchers 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact Induction training into Public Enagagement for 1st Year PhD students
Year(s) Of Engagement Activity 2015
 
Description Quarterly meetings Dr Tilo Kunath 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Patients, carers and/or patient groups
Results and Impact Informal themed meetings with keynote speaker giving updates about research activities, and other areas of interest (e.g. care opportunities, things to improve quality of life, coffee / cake informal chat sessions)
Part of a general objective of disseminating information concerning regenerative medicine, generating interest in this field. But also question at panel session from attendee to check if one could smell Parkinson's which led to a new research study using super smellers. News story: http://www.crm.ed.ac.uk/news/skin-scent-offers-parkinson%E2%80%99s-hope
Year(s) Of Engagement Activity 2015
 
Description RSE Lecture: Innovation in Organ Transplantation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Lecture given at Royal Society of Edinburgh: Innovation in Organ Transplantation
Year(s) Of Engagement Activity 2018
 
Description Raman Spectroscopy Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact To explore using Raman Spectroscopy in Regenerative Medicine, the Niche Hub, together with OPTIMA-CDT and the Chemistry and Computational Biology of the Niche research facility (CCBN) held a one day workshop (Edinburgh, 23/02/2016). The day ended with a round table discussion on how to further the translation of Raman into regenerative medicine, which has resulted in an MRC Confidence in Concept award and a discussion paper which will appear in print later this year (npj Regenerative Medicine).
Year(s) Of Engagement Activity 2016
 
Description Regenerate! - 2014 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact 'Regenerate!' is a £30k Wellcome Trust funded project (01 Dec 2013 - 31 Dec 2014), with in kind contributions from CRM's scientific communications manager, MRC funded CRM based PhD students and other public engagement specialists based at CRM. The project aims to provide teachers, particularly in remote areas of Scotland, with up-to-date knowledge of stem cells and free teaching resources for use in their classrooms. As such the project has organised CPD training sessions and has delivered schools workshops with these materials to further help teachers deliver these sessions themselves afterwards. Full data are not available yet, but to date we have delivered workshops (740 pupils total) in Shetland (180 pupils), Orkney (105 pupils), Thurso (160 pupils), Skye (90 pupils), Fort William (80 pupils), Dumfries (65 pupils), Dunoon (60 pupils), Outer Hebrides (Lewis, Benbecula, Barra, number of pupils unknown), and some local schools in Scotland's central belt area. In these areas (and others) we have thus far delivered 16 CPD training sessions, with 79 teachers attending from 46 different schools. 48 kits with educational materials have been distributed after the CPD training session. In addition we organised a GLOW digital CPD training session, which 50 teachers attended.


Part of a general objective of disseminating information concerning regenerative medicine, generating interest in this field.
Year(s) Of Engagement Activity 2014
URL http://www.eurostemcell.org/regenerate
 
Description Regeneration Innovation 2018 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Workshop to encourage and stimulate translation and commercialisation of research from the CRM. Speed networking and an innovation competition were included as acitvities as well as presentations from existing industry collaborations.
Year(s) Of Engagement Activity 2018
 
Description Regeneration | Innovation 2017: industry engagement 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact A networking meeting: a series of talks by MRC-CRM scientists and industry collaborators.
Year(s) Of Engagement Activity 2017
 
Description Regeneration: a story of becoming 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact An exhibition of art by staff: Claire Cryer, Melany Jackson, Marie Bechler, Rosa Migueles, Guillaume Blin, Julia Watson, Kirsty Ferguson, Andrew Jarjour. Science Communication Manager worked with an MSc student to deliver the exhibition as part of the MRC Festival of Medical Science. Participants felt they had engaged in science and that the art encouraged them to engage in a way that other forms of communication would not. Several new stakeholder contacts made.
Year(s) Of Engagement Activity 2017
 
Description Repeat of Eradicate Parkinsons?! Talk with John McPhee at Parkinsons UK Scotland Meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Supporters
Results and Impact Repeat of Eradicate Parkinson's?! Talk with John McPhee at Parkinson's UK Scotland Meeting. Dr Kunath met New Scotland Director for Parkinson's UK
Year(s) Of Engagement Activity 2017
 
Description Royal Society public lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Live streamed public lecture, followed by questions and discussion. Video available

Knowledge sharing and building of public understanding of stem cells and regenerative medicine
Year(s) Of Engagement Activity 2014
URL https://royalsociety.org/events/2014/stem-cells/
 
Description Runner up in MRC Max Perutz Science Writing prize 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Sophie Quick runner up for her essay "Watering the strawberry fields of the mind" https://www.insight.mrc.ac.uk/2017/11/30/watering-the-strawberry-fields-of-the-mind/
Year(s) Of Engagement Activity 2017
URL https://www.insight.mrc.ac.uk/2017/11/30/watering-the-strawberry-fields-of-the-mind/
 
Description School Pupil Mentoring Scheme 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact MRC-CRM PhD students and postdocs meet with secondary school pupils to provide mentoring support in their studies and career deliberations.
Year(s) Of Engagement Activity 2016,2017
 
Description School lesson as part of UniStem day 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact CRM PhD Student Eleni Karigianni developed a school lesson about developmental biology and delivered this at the local secondary school Castlebrae High School. 3 higher biology students attended the lesson.
Year(s) Of Engagement Activity 2015
 
Description School lesson as part of UniStem day 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact CRM PhD Student Eleni Karigianni developed a school lesson about developmental biology and delivered this at the local secondary school Castlebrae High School. 3 higher biology students attended the lesson.
Year(s) Of Engagement Activity 2015
 
Description School visit 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact 28 October 2015. CRM PhD student Eleni Karagianni visited Preston Lodge High School to deliver two 1hr lessons to Advanced and Higher Biology students (13 + 6 students). Topic of the lesson was developmental biology and stem cells.
Year(s) Of Engagement Activity 2015
 
Description School workshop 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact 19 Nov 2015. PhD Student Kim Lee Son (Monica) in Prof Charles ffrench-Constant's lab gave two workshops for p6 / 7 schoolchildren. Location: West Linton Primary School, Deanfoot Road, West Linton, EH46 7EX. Project: Research The Headlines (http://researchtheheadlines.org/). Session 1: ~28 P6 students, 1 class teacher, 1 assistant teacher. Session 2: ~33 P7 students, 1 class teacher. What I did: I introduced myself as a UoE PhD student studying cells involved in multiple sclerosis. I then went through the presentation for Research The Headlines workshop with the students, allowing for engagement through asking them to write their own headlines for each of the examples (salmon vs. pizza - fat content, chocolate - healthy or not?, exercise - is 2 minutes enough?, Parkinson's disease and smell research), getting them to discuss with each other, and then to read them out loud. The students, particularly those in P6, also asked questions on what it was like to be a researcher and science in general. The teachers mentioned that a lot of students in their classes were interested in science, so they were, for the majority of them, very involved and engaged with the workshop.
Year(s) Of Engagement Activity 2015
 
Description School's visit (Whitburn Academy) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact What: 8 students (Higher Biology) and teacher from Whitburn Academy, West Lothian High School students visited CRM. Cathy Southworth and Susan Gallogly gave a tour and Susan talked about her work and experience working as a PhD student at CRM (career path). The students will write a blog for the Eurostemcell website.
Year(s) Of Engagement Activity 2014
 
Description Schools Visit (Whitburn Academy) 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact What: 8 students (Higher Biology) and teacher from Whitburn Academy, West Lothian High School students visited CRM. Cathy Southworth and Susan Gallogly gave a tour and Susan talked about her work and experience working as a PhD student at CRM (career path). The students will write a blog for the Eurostemcell website.
Year(s) Of Engagement Activity 2014
 
Description Science Insights Work Experience Programme 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Science Insights is a week long work experience programme for secondary school pupils entering S5. MRC-CRM participates with other Centres in lab visits and ethical debates as well as supporting the overall organisation of the programme.
Year(s) Of Engagement Activity 2016
URL http://www.ed.ac.uk/medicine-vet-medicine/outreach/science-insights
 
Description Science Insights Work Experience Week 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact A week long programme of work experience: including talks, tours, lab taster sessions, careers advice from Centre staff. Very positive feedback from the 40 pupils who took part: e.g. "I learned about some current research projects, what it is like to work as a researcher and ways into these type of careers" and "Science insights has been brilliant as I've met new people and have a clear idea of my future now." Co-organised by Centre Science Communication Manager.
Year(s) Of Engagement Activity 2017
URL https://www.ed.ac.uk/news/2017/pupils-gain-insight-into-scientific-careers
 
Description Science Insights works experience week 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Pupils report being inspired to study medical science subjects, learning more about Medical Research, the breadth of research, its challenges and careers in science.
Year(s) Of Engagement Activity 2018
URL http://www.scienceinsights.ed.ac.uk
 
Description Signing Science Workshop 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact 7 pupils and 2 teachers learned new sign language terms relating to our research and watched translated talks and had tours of labs
Year(s) Of Engagement Activity 2017
 
Description Spagetti Brains and Stem Cells 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact As part of the 'Pint of Science' program. Tuesday 24 May 2016, evening event at the City Cafe. Dr Tilo Kunath. STEM CELLS AND SNIFFING OUT PARKINSON'S DISEASE CRM Researcher Dr Tilo Kunath (Chancellors Fellow) talked about: What is so special about stem cells? What is all the hype about? And how on earth did research into stem cells lead to investigations into whether Parkinson's has a unique odour? He described the different kinds of stem cells: human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells and explore how they are being used for research and as a treatment. He also described how serendipity led him to discover Joy Milne, and her amazing ability to sniff out Parkinson's. Dr Veronique Miron also took part in the event (former postdoc at CRM who then set up her own group at the Centre for Reproductive Health).
Year(s) Of Engagement Activity 2016
URL https://pintofscience.co.uk/event/spaghetti-brains-and-stem-cells
 
Description Stand at 'Living with MS' conference 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Patients, carers and/or patient groups
Results and Impact "Date: Saturday 25 April 2015.
Time: 09:00-15:30
• Venue: Grand Central Hotel Glasgow, 99 Gordon Street, G1 3SF
Audience: The day is attended by a range of people from those who are newly diagnosed to those who have been living with MS for some time. Carers, family members and partners also attend.
Expected attendance: 150 from across Scotland.
CRM PhD students Catriona Ford and Matthew Swire took some public engagement conversation starter props with them, talked to patients about their work on MS and provided opportunities for patients to ask questions, start a dialogue.
"
Year(s) Of Engagement Activity 2015
 
Description Stem Cell Sign Language Development 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact A one day workshop to develop stem cell terms for a Biology Sign Language Glossary. This will develop into a wider campaign to promote the terms and their use to school pupils, college/university students, members of the deaf community interested in research and the ethical issues arising.
Significant engagement to limited posting on social media.
Year(s) Of Engagement Activity 2017
 
Description Student placements 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Sept-Dec 2015 and Jan-March 2016. Four student placements at CRM. Two from Master in Science Communication working on evaluating EuroStemCell with Jan Barfoot (Autumn 2015), two with Ingrid Heersche evaluating DrSkelfie Social Media account (Jan-March 2016)
Year(s) Of Engagement Activity 2015
 
Description Teachers Training Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact 24 teachers from across Scotland funded by RCUK through SSERC
CRM contribution - Research Talk by Prof Anna Williams, resources and resource walk through by Dr Cathy Southworth
Year(s) Of Engagement Activity 2017
 
Description TeamRegeneratED Twitter Account 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact A group of stem cell scientists in the Centre tweeting about their research, their colleagues, stem cell science in general. 381 followers to date. Their #StemCellHistory developed with an artist has been particularly popular https://twitter.com/TeamRegeneratED/status/750710816572338177
Year(s) Of Engagement Activity 2015,2016,2017
URL https://twitter.com/TeamRegeneratED
 
Description The Woman who can smell Parkinsons Disease 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Dr Tilo Kunath was intervied as part of the documentaty on BBC Scotlandhttps://www.bbc.co.uk/programmes/b09jgxdv
Year(s) Of Engagement Activity 2017
URL https://www.bbc.co.uk/programmes/b09jgxdv
 
Description Tour of Facility 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Tour of facility by Head of New Technology from Sanofi-Genzyme
Year(s) Of Engagement Activity 2017
 
Description Towards Dolly: a century of animal genetics in Edinburgh. Exhibition 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Undergraduate students
Results and Impact Towards Dolly: a century of animal genetics in Edinburgh, a free exhibition at the Main Library (George Square), 31 July - 31 October 2015. 12,000 visitors, University of Edinburgh students, Fringe festival visitors, other adult lay audience. It included the legacy of Dolly the cloned sheep, amongst which stem cell research. CRM work was highlighted, for example with two A0 teratoma images of Dr Keisuke Kaji.
Year(s) Of Engagement Activity 2015
 
Description Translate! 2014 Open Forum for Translational Research, Berlin, Germany, May 23rd 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Molly Stevens presented "Technology-driven Translational Research:Does Material Science ever Meet a Medical Need?" followed by discussion.

Shared knowledge with translational research practitioners
Year(s) Of Engagement Activity 2014
URL http://translate-event.charite.de/?page_id=2
 
Description Visit and lab tour 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Supporters
Results and Impact 29 September 2015. Dr Steve Pollard hosted a visit for 11 Coral employees who have raised £1M for the Charity Children with Brain Cancer. They visited CRM, Steve showed them round the building and labs and talked about the latest research developments in this field.
Year(s) Of Engagement Activity 2015
 
Description Visit by Ash Denham MSP 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Ash Denham MSP visited the Centre to find out more about our community engagement activity, particularly with a local High School
Year(s) Of Engagement Activity 2016
 
Description West College Scotland 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Industry/Business
Results and Impact West College Scotland - college students visited and heard talks about the science of the Centre, careers in science and toured facilities. The lecturer fed back "The students have been raving on about it and their feedback was great. They felt that it was a privilage to be allowed access to the labs and they have gained a lot of insight not only into the latest in stem cell research but also into where their science career can go. I have one student who is now considering the bio-informatics route!"
Year(s) Of Engagement Activity 2017
 
Description Who wants to live forever? 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact "9 September 2015, Bradford, British Science Festival. Discussion 'Who Wants to Live Forever' involving Dr Tilo Kunath. 40 attendees, mainly lay adult audience. https://thelittleboxoffice.com/bsa/event/view/26571. Host and Chair: Iszi Lawrence
James Stark provided Opening Comments."
Year(s) Of Engagement Activity 2015
 
Description You can be a doctor! 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact "27 November 2015. CRM (Cathy Southworth) played host to 'You can be a doctor!', a project set up by Edinburgh University medical students to encourage equal opportunity for young people in becoming doctors. Clinical CRM PhD student John Hallet spoke to 34 secondary school students who visited the building for the afternoon. Presentations and a building tour by other CRM Clinical PhD students Jennifer Easterbrook and John Hallet. More information about the You Can Be a Doctor Program:
http://youcanbeadoctor.co.uk
You Can Be a Doctor is a website designed and written by a team of senior medical students at the University of Edinburgh and is aimed at state school pupils who are thinking about studying medicine at university. The team passionately believe in equal opportunity for young people from areas and schools that do not have a tradition for producing medical students.
"
Year(s) Of Engagement Activity 2015
 
Description Youth Grand Challenge Competition Winners Visit to the MRC CRM 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact British Science Association Youth Grand Challenge competition winners, came to the Centre from Wales, met researchers, heard about our research and toured the facilities.
Year(s) Of Engagement Activity 2018
 
Description Zebrafish School Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact Zebrafish School Workshop; Led by Engagement Manager Dr Cathy Southworth
Year(s) Of Engagement Activity 2017
 
Description £4M bid to find therapies that prompt tissues to repair 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Press release to highlight successful award of funding for UKRMP2 Hub.
Tom Feilden from the Today Programme was interested in doing a follow up to this. This was subsequently delayed. We intend to follow up.
University press release https://www.ed.ac.uk/news/2018/ps4m-bid-to-find-therapies-that-prompt-tissues-to
Year(s) Of Engagement Activity 2018
URL http://www.crm.ed.ac.uk/news/4m-bid-find-therapies-prompt-tissues-repair