MICA: Reducing cardiovascular disease risk through replacement of saturated fat in milk and dairy products

Lead Research Organisation: University of Reading
Department Name: Food and Nutritional Sciences

Abstract

Within the UK, Europe and North America heart disease is the major cause of ill health and death. Diet has an important impact on heart disease risk and studies have shown that good dietary habits at a young age and throughout the lifespan can reduce the excessive economic and social burden associated with heart disease, by helping to prevent or delay its development. The Department of Health has dietary recommendations to reduce disease risk, principally a reduction in total saturated fat (hard fats found in processed and animal derived foods) intake. However currently, the UK population considerably exceeds this saturated fat target. Milk and milk products are one of the largest sources of dietary saturated fat, contributing about 30% of the total with cheese and butter contributing most. A common strategy to reduce saturated fat intake is to advise reduction or removal of milk and dairy products from the diet. However milk is an important food providing essential nutrients such as calcium, B vitamins and iodine, particularly important for children, young women and older adults and their reduction may lead to detrimental effects on nutritional status and health. In addition, evidence suggests that there are likely to be benefits of increased dairy food consumption such as milk in terms of lower blood pressure, reduced incidence of heart disease and some cancers, although there is limited evidence for cheese and butter. Thus simply reducing milk intake to reduce saturated fat consumption is likely to be counterproductive. Studies with humans where blood cholesterol has been measured suggest that replacing a proportion of the saturated fat in the diet with mono or polyunsaturated fats (typically found in vegetable oils) does improve their cardiovascular health value. There is now good evidence that changing the diet of the dairy cows can provide a sustainable means of producing milk with reduced saturates and increased monounsaturates, although because of the complex nature of dairy foods it cannot be simply assumed that such modified foods will reduce the risk of heart disease. Such changes to the diet of the dairy cow may also have environmental benefits as they are likely to reduce the amount of methane (a potent greenhouse gas) produced by the cow thus reducing the carbon footprint associated with milk production. This project will examine the health benefits of such modified milk and dairy products in controlled human and laboratory studies using traditional and new methods of assessing heart disease risk. In the first part of the project, dairy products with reduced saturated fats and increased monounsaturated fats will be produced by changing the cow's diet. A detailed human study will then be undertaken to assess the long and short-term effects of including these dairy products in the diet and individual meals. New, more valuable methods of assessing changes in the risk of heart disease will be included as these are thought to be more predictive than the traditional approaches relying on blood cholesterol. In the third part of this project we will complement the human studies by determining in the laboratory how the modified milk and commercial dairy products influence the health of human blood vessels, such as those found in the heart. Any benefits arising from this work will inform public health policy on optimum dietary strategies to prevent or delay the onset of heart disease.

Technical Summary

UK exceeds dietary targets for SFA recommended for CVD risk reduction. Milk/milk products are one of the largest sources (30% of total SFA). Recent data show likely benefits of increased milk consumption in reduced CVD risk thus consuming less milk/products to lower SFA intake may be counterproductive. Recent studies by our group (funded by BBSRC DRINC) show the potential of dairy cow nutrition to produce reduced SFA and increased cis-MUFA milk in a sustainable fashion. The hypothesis that consumption of such low-SFA dairy foods will reduce CVD risk in those at increased risk, compared with normal dairy foods, via mechanisms to increase secretion of endothelial-derived vasodilators will be tested. Initially, reduced SFA/enhanced cis-MUFA milk, cheese and butter will be produced by cow dietary changes. These modified foods will be used in double-blind, randomised, controlled, crossover chronic and acute studies with adults at increased CVD risk (n=54) to assess their effects in the background diet (12-weeks) and in test meals on biomarkers of CVD. These will include traditional (lipids and blood pressure) and novel markers (vascular function, determined by flow mediated dilatation and stiffness, pulse wave velocity), postprandial lipids, biomarkers of inflammation and vascular function (cellular adhesion molecules, endothelial progenitor cells). Furthermore, this project will use a co-culture system (human aortic smooth muscle cells overlayered with endothelial cells) which more closely mimics physiological systems, to examine the responses to plasma isolated during the acute postprandial studies on gene expression and protein levels of biomarkers of vascular function and endothelial vasodilators (including nitric oxide), providing a novel insight into mechanisms of action of low-SFA dairy products. These studies will provide unique evidence to inform public health policy on sustainable food-based dietary recommendation for CVD risk reduction.

Planned Impact

Given the widespread consumption of milk and dairy products and the fact that they are major contributors of saturated fatty acids (SFA) in the diet, this work will have a significant impact on a wide range of beneficiaries as diverse as the general public, food production and retailing industries, the NHS and UK agriculture. Modification of milk fat composition as proposed would remove some 70,000 tonnes/year of SFA from the UK food chain. This would be a true removal rather than a movement of the SFA into other food chain entry points. Key beneficiaries include:
The public: This research will impact on the development of novel dietary and food-based strategies to reduce the risk of CVD. CVD remains the main cause of mortality and morbidity in the UK/EU and the US and is rapidly becoming a major issue in countries such as China. It has major effects on quality of life. The public would thus benefit directly from the reduced CVD risk, but also financially since less public finance would be needed for health care. CVD is estimated to cost the EU economy directly and indirectly some 200 billion EUR per year and thus even small reductions in CVD risk would have major implications on health care costs.
The consumer: Availability of SFA reduced dairy products would give consumers of all ages greater healthy food choices, without the need for dairy food exclusion.
The NHS: Diet, a major moderator of CVD risk will play an increasingly important role and lipid quality is a crucial aspect of diet. This work would make the achievement of dietary SFA reduction targets more likely leading to reduced CVD risk. This would relieve considerable pressure on the NHS both financially and resource-wise. Crucially the effect would start in childhood and would thus be preventative throughout adulthood reducing the need for pharmaceutical (e.g. statins) intervention later in life. It would provide health professionals, including dieticians, with new tools for designing healthy diets.
Food production and retailing industries: Milk and dairy companies will benefit from increased uptake of their products and retail companies will benefit from increased sales. Both will benefit from a healthy food image. This proposal includes a commercial partner Milk Link which is the UK's largest producer of cheese and supplies all major food retailers, food processors and food service organisations. It also manufactures a wide range of dairy products including long life milk and cream, extended shelf life products, flavoured milks and milk powders. Milk Link has recently announced a merger with Arla Foods and this will mean that Milk Link will become part of one of Europe's leading dairy co-operatives and dairy food producers. These companies will benefit directly from new knowledge gained from being involved in the research and in the longer term as outlined above. Moreover, as this project complements a current BBSRC/DRINC grant, feedback of findings etc will occur through DRINC members which includes major companies involved with dairy products including Danone, Kraft Foods, Nestlé, Marks and Spencer and Unilever.
UK Agriculture: Whilst an increase in food production is necessary as population size increases, this must be done in ways which are sustainable and recognise the need for foods to be healthy. This work will provide opportunities for UK agriculture to achieve these aims. It will increase the need to produce home grown rapeseed, a sustainable product which will provide UK dairy farmers with feed inputs which produce healthier dairy products at a reduced carbon cost.
Government and related policy making bodies: These bodies are responsible for UK diet and health policy. They will benefit from information which can feed into future dietary policy aimed at reducing CVD risk. It will allow them to promote good health and well being through staple food intervention and provide better understanding of the link between food production and consumer health.

Publications

10 25 50
 
Description AAK (UK) Ltd. 
Organisation AAK UK
Country United Kingdom 
Sector Private 
PI Contribution We acknowledge their contribution in our research dissemination and keep them up to date with our research progress and outputs at biannual progress meetings.
Collaborator Contribution AAK have provided us with the oil supplement (high-oleic sunflower oil) that is necessary for the bovine feeding aspect of our MRC project.
Impact Effect of feeding high-oleic sunflower oil to dairy cows on the milk fatty acid profile - RESET study. Oral presentation at the Nutrition Society Annual Summer Meeting, Glasgow-UK, July 2014.
Start Year 2013
 
Description Arla Foods 
Organisation Arla Foods
Country United Kingdom 
Sector Private 
PI Contribution We acknowledge their contribution in our research dissemination and keep them up to date with our research progress and outputs at biannual meetings.
Collaborator Contribution Arla have provided us with the commercially available dairy products that are used in our study and the starter cultures for our modified cheese production. They are also carrying out some sensory analysis of the dairy products being used in our human intervention study.
Impact Effect of feeding high-oleic sunflower oil to dairy cows on the milk fatty acid profile - RESET study. Oral presentation at the Nutrition Society Annual Summer Meeting, Glasgow-UK, July 2014.
Start Year 2013
 
Description Collaboration with MRC Human Nutrition Research Unit, Cambridge 
Organisation Medical Research Council (MRC)
Department MRC Human Nutrition Research Group
Country United Kingdom 
Sector Academic/University 
PI Contribution We provided ca. 900 fasting and postprandial plasma samples from our human intervention study for lipid analysis
Collaborator Contribution Our partners analysed provided us with data on the plasma phospholipid FA profiles of ca. 900 fasting and postprandial plasma samples from our human intervention study
Impact An abstract was submitted to present some of the results at The International Society for the Study of Fatty Acids and Lipids (ISSFAL) Congress, Sept 2016. A paper has been published: Markey O, Vasilopoulou D, Kliem KE, Koulman A, Fagan CC, Summerhill K, Wang LY, Grandison AS, Humphries DJ, Todd S, Jackson KG, Givens DI, Lovegrove JA. Plasma phospholipid fatty acid profile confirms compliance to a novel saturated fat-reduced, monounsaturated fat-enriched dairy product intervention in adults at moderate cardiovascular risk: a randomized controlled trial. Nutr J. 2017 May 23;16(1):33.
Start Year 2015
 
Title Reducing cardiovascular disease risk through replacement of saturated fat in milk and dairy products: the RESET study 
Description The hypothesis that consumption of such low-SFA dairy foods will reduce CVD risk in those at increased risk, compared with normal dairy foods, via mechanisms to increase secretion of endothelial-derived vasodilators will be tested. Initially, reduced SFA/enhanced cis-MUFA milk, cheese and butter will be produced by cow dietary changes. These modified foods will be used in double-blind, randomised, controlled, crossover chronic and acute studies with adults at increased CVD risk (n=54) to assess their effects in the background diet (12-weeks) and in test meals on biomarkers of CVD. These will include traditional (lipids and blood pressure) and novel markers (vascular function, determined by flow mediated dilatation and stiffness, pulse wave velocity), postprandial lipids, biomarkers of inflammation and vascular function (cellular adhesion molecules, endothelial progenitor cells). The human intervention study has been underway since March 2014 and we are actively recruiting volunteers. 
Type Preventative Intervention - Nutrition and Chemoprevention
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2013
Development Status Actively seeking support
Impact Any benefits arising from this work will inform public health policy on optimum dietary strategies to prevent or delay the onset of heart disease. 
URL http://clinicaltrials.gov/ct2/show/NCT02089035?term=lovegrove&rank=3
 
Description ' Dairy foods for key life stages': Modern Dairy Science and Technology, University of Reading, UK 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact A training course for dairy technologists and it will be repeated in April 2016
Year(s) Of Engagement Activity 2015
 
Description 'Consumer acceptance of saturated fat-reduced dairy products: a novel approach for reducing intake of saturated fat at a population level.': Nutrition Society Annual Conference, Nottingham, UK 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Over 100 individuals (from industry and academia) attended this forum; it provided a common meeting place for scientists and companies to exchange knowledge.
Year(s) Of Engagement Activity 2015
 
Description 'Dairy foods, dietary partners for life?' : University of Milan ASPA Conference, Milan, Italy 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Scientists, health professionals from around the EU
Year(s) Of Engagement Activity 2015
 
Description 'Dairy foods, dietary partners for life?': Dairy UK Seminar and dinner, London, UK 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Levy bodies, industry, dairy farmers.
Year(s) Of Engagement Activity 2015
 
Description 'Effect of dairy food matrix on absorbability of fat': SFA Expert Meeting: Leiden, The Netherlands 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact World experts of dietary fat and health attended this event. A policy related paper is in preparation.
Year(s) Of Engagement Activity 2015
 
Description 'Effect of feeding high-oleic sunflower oil on the fatty acid composition of bovine milk and dairy products': Agri-Innovation Workshop: Building resilience to climate change in Malaysia through innovative and sustainable agricultural technologies, Selangor,Malaysia. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact This Workshop will take place in mid-March 2016. I will have an opportunity to share the findings of Workpackage 1 of the RESET study with other Workshop attendees.
Year(s) Of Engagement Activity 2016
 
Description 'Impact of a high-oleic sunflower oil bovine feeding regimen on the fatty acid profile of milk and dairy products:' European Food Safety Authority (EFSA) conference: Shaping the Future of Food Safety, Together, Milan-Italy 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact This provided a forum to increase awareness about findings of the RESET study (workpackage 1)
Year(s) Of Engagement Activity 2015
 
Description 'Impact of dairy fat on cardiometabolic risk': Saturated Fat, Dairy and Cardiovascular Disease: A Fresh Look at the Evidence-Regional conferences on Saturated Fat, Cardiff, Glasgow, London 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Health professionals, dairy industry and farmers
Year(s) Of Engagement Activity 2015
URL http://www.milk.co.uk/page.aspx?intpageid=484
 
Description 'Milk and dairy: Dietary partners for life?': NML -Sustainability of UK dairy supply chains, Somerset, UK 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Dairy and related supply industries
Year(s) Of Engagement Activity 2015
 
Description 'Milk and dairy: Dietary partners for life?': University of Reading Agriculture and Food Investigation Team national event, Reading, UK 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Agriculture and food economists from around the UK who are involved in farm management data analysis for DEFRA, DEFRA staff
Year(s) Of Engagement Activity 2016
 
Description 'New perspectives on dairy intake and cardiovascular risk': Plenary Lecture. 'Clearing up the Science Fiction on Dietary Fats,' London, UK 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Influence clinical practice
Year(s) Of Engagement Activity 2016
 
Description 'New perspectives on dairy intake and cardiovascular risk': Plenary Lecture. Nutrition Society's Annual Summer Meeting- The future of animal products in the diet: health and environmental concerns,' Nottingham, UK 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact A paper, based on this presentation, is 'in press' (see publications).
Year(s) Of Engagement Activity 2015
 
Description 'Role of dairy foods as suppliers of key nutrients during childhood, pregnancy and later life': BAFSAM conference, Solihull, UK 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Industries from around the EU concerned with trace elements and vitamins. This talk highlighted the importance of incorporating diary into the diet and raised awareness to the RESET project
Year(s) Of Engagement Activity 2015
 
Description 'Science Fats or Science Fiction': Public Lecture, London, UK 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Inform public
Year(s) Of Engagement Activity 2016
 
Description All Parliamentarian Food and Health Forum, House of Lords, London (Debate) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Awareness was raised about the valuable research that is being undertaken as a result of the MRC funding. People are interested in being kept up to date with how the research progresses as it could have important implications for public health nutrition and inform decision-making and policy.



Plans made for future related activity.
Year(s) Of Engagement Activity 2014
 
Description Animal-derived foods for improving diets across the life stages: Do they have a future?: International Conference: Steps To Sustainable Livestock, University of Bristol, UK 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Scientists and policy makers from across the world, UN FAO, Health Professionals. A further grant application in collaboration with University of Bristol and Rothamsted (North Wyke) resulted.
Year(s) Of Engagement Activity 2016
 
Description BAFSAM conference, Solihull, 2015 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Role of dairy foods as suppliers of key nutrients during childhood, pregnancy and later life. Participants: Industries from around the EU concerned with trace elements and vitamins
Year(s) Of Engagement Activity 2015
 
Description CommUnity magazine and Institute for Cardiovascular and Metabolic Research (ICMR) Highlights Magazine (Reading, UK) 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact The CommUnity magazine is published twice a year and is delivered to 15,000 local residents. As a result of this article, we have had increased interest from the local people and a number of people have contacted us to express interest in taking part in our human study.



Dairy product consumption is often negatively portrayed in the media. Our article highlighted some of the beneficial aspects of dairy consumption, which are often forgotten. We have had a lot of interest from local individuals who are interested in taking part in the study.
Year(s) Of Engagement Activity 2014
 
Description Dairy UK Seminar 'How Good? How Green? Does Dairy Deliver?', London, 2015 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Dairy UK Seminar 'How Good? How Green? Does Dairy Deliver?' Talk title: Dairy foods, dietary partners for life? Participants: Levy bodies, industry, dairy farmers
Year(s) Of Engagement Activity 2015
 
Description Dairy in cardiovascular health and metabolic syndrome: What is the evidence?: Utrecht Group International Workshop, Utrecht, The Netherlands 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Inform policy
Year(s) Of Engagement Activity 2015
 
Description Diet and the vasculature- Vascular function workshop. (HNR-MRC University of Cambridge) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Type Of Presentation keynote/invited speaker
Geographic Reach Regional
Primary Audience Other audiences
Results and Impact This talk sparked questions and potential future collaboration.

Another, aim of this workshop was to gain insight into how to carry out the 'carotid-intima media thickness' technique so that we could establish the method in our Lab. Dr Sumantra Ray and his team at the MRC Human Nutrition Research Unit (HNR), Cambridge have vast experience in this technique -we benefited greatly from their feedback and expertise.
Year(s) Of Engagement Activity 2014
 
Description Effect of feeding high-oleic sunflower oil to dairy cows on the milk fatty acid profile - RESET study. Oral presentation at the Nutrition Society Annual Summer Meeting, Glasgow-UK, July 2014. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation paper presentation
Geographic Reach National
Primary Audience Other audiences
Results and Impact Approximately 60 academic peers attended this well-received talk. It was followed by an interesting discussion. People are interested in hearing about how this project progresses.

People have contacted us asking for further information about the study.
Year(s) Of Engagement Activity 2014
URL http://www.nutritionsociety.org/
 
Description Healthy Cows, Healthy Humans, Healthy Planet, Reading-UK, April 2014. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Type Of Presentation keynote/invited speaker
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Over 100 individuals (from industry and academia) attended this symposium, which sparked questions and interesting discussion afterwards.

Awareness was raised about the valuable research that is being undertaken as a result of the MRC funding. People are interested in being kept up to date with how the research progresses as it could have important implications for public health nutrition. Valuable links were made with Marks and Spencer who were interested in this concept and study results with a possible view to using a similar product.
Year(s) Of Engagement Activity 2014
URL http://www.nmr.co.uk/downloads/progspeakerprofiles.pdf
 
Description International Conference: Steps To Sustainable Livestock, Bristol, 2016 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact International Conference: Steps To Sustainable Livestock. Title of talk: Animal-derived foods for improving diets across the life stages: Do they have a future? Participants: Scientists and policy makers from across the world, UN FAO, Health Professionals. A further grant application in collaboration with University of Bristol and Rothamsted (North Wyke) resulted.
Year(s) Of Engagement Activity 2016
 
Description Invited Keynote presentations at International conference on Chronic Diseases and Lifestyle. Presentation entitled 'Diet and Cardiovascular Disease Risk'. Lahore, Pakistan. Professor Julie Lovegrove 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited Keynote presentations at International conference on Chronic Diseases and Lifestyle. Presentation entitled 'Diet and Cardiovascular Disease Risk'. Lahore, Pakistan. The audience was mixed, predominantly scientists and included the President of Pakistan. Numbers were 300+. The presentation raised may questions and discussion with further invitations to present and also collaborate
Year(s) Of Engagement Activity 2019
 
Description Invited Keynote presentations at the 30th Anniversary of National Dairy Council Ireland symposium. Presentation entitled 'Dairy and cardiovascular risk'. Coleraine, Northern Ireland. Professor Julie Lovegrove. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Invited presentations (Symposium) KEYNOTE at 30th Anniversary of National Dairy Council Ireland symposium 'Dairy and cardiovascular risk'. Coleraine, Northern Ireland. There were 200+ in the audience with many questions and discussion.
Year(s) Of Engagement Activity 2019
 
Description Invited expert in a round table discussion on the role of dairy products and type 2 diabetes risk: where does the evidence stand in 2017? 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact In November 2017 Professor Ian Givens took part as an invited expert in a round table discussion on the role of dairy products and type 2 diabetes risk: where does the evidence stand in 2017? This took place in Wageningen and was sponsored by Friesland Campina and the Dutch Dairy Association and involved experts from as far away as Canada. It will lead to a high profile paper.
Year(s) Of Engagement Activity 2017
 
Description Invited presentation at International conference. 13th Federation European Nutrition Societies (FENS) meeting. 'Impact of Dairy on Human health: Biomarkers of intake and CVD risk'. Julie Lovegrove. Dublin, Ireland 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentations entitled 'Impact of Dairy on Human health: Biomarkers of intake and CVD risk'. 13th Federation European Nutrition Societies (FENS) meeting.Dublin, Ireland. Julie Lovegrove. 100+ scientists, students, industry members, policy makers attended.
Year(s) Of Engagement Activity 2019
 
Description Invited presentation at a workshop entitled "Inter-esterified fats in the food chain". British Nutrition Foundation. Professor Julie Lovegrove 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited presentation at a workshop entitled "Inter-esterified fats in the food chain". organised by British Nutrition Foundation for a BBSRC project. 20 attendees. Discussion and decisions made with a paper published form the workshop
Year(s) Of Engagement Activity 2019
 
Description Invited presentation at scientific workshop for the 2nd Anniversary of the Institute of Food, Nutrition and Health. Entitled "Hugh Sinclair Unit: History, Achievements and Future. Reading, UK. Professor Julie Lovegrove 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited presentation on the research performed at the Hugh Sinclair Unit of Human Nutrition . The audience was mixed and was approximately 90 scientists, those from industry, policy makers.
Year(s) Of Engagement Activity 2019
 
Description Invited presentation by Professor Julie Lovegrove with a title "Dietary Fats and CVD risk. Dispelling the Myths' for the Korean Annual Nutrition Conference (virtual). 13th Nov 2020. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact An annual Conference by the Korean Nutrition Society
Year(s) Of Engagement Activity 2020
 
Description Invited speaker (Ian Givens) at the EAAP 2020 Annual Meeting on the topic of milk/dairy in the diet at key life stages 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited presentation at an internation conference.
Year(s) Of Engagement Activity 2020
 
Description Invited speaker (Ian Givens) at the International Congress on Emerging Topics on Mediterranean Diet, organised by the Italian Society of Human Nutrition 2020 Virtual 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Conference presentation
Year(s) Of Engagement Activity 2020
 
Description Keynote presentation in the Nutrition Society Annual Postgraduate Conference, September 2017, Reading, UK - Dietary dilemmas over fats and heart disease-Professor Julie Lovegrove 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Professor Julie Lovegrove was a keynote speaker giving a presentation entitled 'Dietary dilemmas over fats and heart disease'
Year(s) Of Engagement Activity 2017
URL https://www.nutritionsociety.org/events/student-conference-2017
 
Description Milk, nutritious by nature Symposia, Dublin, Belfast, Paris 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Talk sparked questions and discussion afterwards

To be added
Year(s) Of Engagement Activity 2014
URL http://www.milknutritiousbynature.eu/fileadmin/apps/milk_default_v3/dossiers/2014_English.pdf
 
Description Modern Dairy Science and Technology, Reading, 2015 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other audiences
Results and Impact Modern Dairy Science and Technology. Title of Talk: A training course for dairy technologists mainly. Participants: A training course for dairy technologists mainly. Will be repeated in April 2016
Year(s) Of Engagement Activity 2015
 
Description NML -'Sustainability of UK dairy supply chains', Yeo Valley HQ, 2015 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Industry/Business
Results and Impact NML -'Sustainability of UK dairy supply chains'. Title of talk: Milk and dairy: Dietary partners for life? Participants: Dairy and related supply industries
Year(s) Of Engagement Activity 2015
 
Description Nordic Lidid Forum, Copenhagen, Denmark (Oral presentation) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Over 100 individuals (from industry and academia) attended this forum; it provided a common meeting place for scientists and companies to exchange knowledge.


Awareness was raised about the valuable research that is being undertaken as a result of our MRC funding. People are interested in being kept up to date with how our research progresses and believe that it could have important implications for public health nutrition.
Year(s) Of Engagement Activity 2014
URL http://www.lipidforum.info/
 
Description Podcast entitled "Challenges in Nutrition Research" made for the NIHR. Professor Julie Lovegrove 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Podcast covering "Challenges in Nutrition Research" made for the NIHR in their Health Research futures series. to a wide audience mainly aimed at health care professionals but access to other audiences.
Year(s) Of Engagement Activity 2020
 
Description Presentation at College of Medicine's annual training event 2017 for members on the theme 'Food: The Future Medicine' 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Ian Givens contributed to the College of Medicine's annual training event 2017 for members on the theme 'Food: The Future Medicine'. This event was fairly GP based but with other specialities. RESET was featured.
Year(s) Of Engagement Activity 2017
 
Description Presentation at WIAS Science Day 2017. (Professor Ian Givens) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact In February 2017 Professor Ian Givens was an invited as a keynote speaker at the WIAS Science Day 2017. This event is an annual, one-day symposium organised by PhD students in Wageningen University. This event focused on sustainable food production
Year(s) Of Engagement Activity 2017
 
Description Presentation at a roadshow giving lectures on milk, dairy products and health 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact In November/December 2017 Professor Ian Givens took part in a roadshow giving lectures on milk, dairy products and health in The Hague, Brussels, Copenhagen, Belfast and Dublin. This was sponsored by the European Milk Forum and focused on the nutrition/functional effects of the food matrix in dairy products. RESET was featured
Year(s) Of Engagement Activity 2017
 
Description Presentation for 50th Anniversary meeting of the UK Society of Feed Technologists. I spoke on 'Healthy Milk - nutritional strategies' 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact In June 2017 Professor Ina Givens was an invited speaker at the 50th Anniversary meeting of the UK Society of Feed Technologists. I spoke on 'Healthy Milk - nutritional strategies' RESET was featured
Year(s) Of Engagement Activity 2017
 
Description Presentations at the British Nutrition Foundation's 50th Anniversary Conference in October 2017: Who is shaping the food choices of the future? 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Professor Ina Givens gave an the invited presentations at the British Nutrition Foundation's 50th Anniversary Conference in October 2017: Who is shaping the food choices of the future? This held in St Thomas' Hospital in the presence of the Princess Royal who met all speakers and BNF personnel individually at lunchtime. RESET was featured
Year(s) Of Engagement Activity 2017
 
Description Presentations in Cardiff, Birmingham and London as an invited speaker to symposiums organised by the Dairy Council 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact In June 2017 Professor Ian Givens undertook presentations in Cardiff, Birmingham and London as an invited speaker to symposiums organised by the Dairy Council. RESET was featured.
Year(s) Of Engagement Activity 2017
 
Description Protein nutrition and novel protein ingredients in the 21st century - tackling the 'protein problem'< Manchester, 2015 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Animal-derived foods and their impact on human health. Participants: Academics from UK universities and researchers from India. This was funded by the Royal Society and a policy focussed report has been sent to the Royal Society and government agencies in India
Year(s) Of Engagement Activity 2015
 
Description Recruitment talks at the Lion's Club of Reading and the Women's Institute (Reading, UK) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact The purpose of these talks was to raise the public's awareness about the impact of dairy product consumption on cardiovascular health and recruit for our dietary human intervention study. The audience enjoyed hearing about the benefits of dairy products and they were keen to find out more about our study.

These talks helped to raise awareness about our study and we have a few new volunteers as a result of our engagement activities.
Year(s) Of Engagement Activity 2014
 
Description Regional conferences on Saturated Fat, Cardiff, 2015 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Impact of dairy fat on cardiometabolic risk. Participants: Health professionals, dairy industry and farmers
Year(s) Of Engagement Activity 2015
 
Description Regional conferences on Saturated Fat, London, 2015 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Impact of dairy fat on cardiometabolic risk. Participants: Industry, health professionals. Led to press coverage.
Year(s) Of Engagement Activity 2015
 
Description Royal Society Summer Exhibition Event, London, 2015 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Schools
Results and Impact Royal Society Summer Exhibition Event. Part of a week-long public exhibition in the Royal Society summer series. In conjunction with University of Bristol and Rothamsted Research. It was focused on beef but issues around dietary fats had read-across from the DRINC study. Participants: Schools, public, interested scientists. This led to a joint submission for research funding under the BBSRC Resilience in the Food Chain scheme.
Year(s) Of Engagement Activity 2015
 
Description SAFA Expert Meeting, Netherlands, 2015 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact SAFA Expert Meeting. Title of Talk: Effect of dairy food matrix on absorbability of fat. Participants: World experts of dietary fat and health.
A policy related paper is in preparation.
Year(s) Of Engagement Activity 2015
 
Description Saturated Fat Expert Panel 1st meeting, London, 2014 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact This was a discussion forum focusing saturated fats and health but with a dairy focus. Participants: Dairy Council staff and academics from Cambridge and Kings College London
Year(s) Of Engagement Activity 2014
 
Description Scientific Council of Bio-competence Centre for Healthy Dairy Products, Estonia, 2016 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Scientific Council of Bio-competence Centre for Healthy Dairy Products. Title of talk Update on the progress of the RESET study. Participants: Administrators and scientists in the Centre
Year(s) Of Engagement Activity 2016
 
Description Scientific Council of Bio-competence Centre for Healthy Dairy Products, Tartu, Estonia 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact This talk will take place on 30 March 2016 and will involve updating the Council on progress with RESET
Year(s) Of Engagement Activity 2016
 
Description Society of Dairy Technology Conference (Nutrition section), on 'The role of milk and dairy products in human health'. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact In April 2017 Professor Ian Givens gave an invited lecture to the Society of Dairy Technology Conference (Nutrition section), on 'The role of milk and dairy products in human health'. This event was hosted by University College, Cork. RESET was featured
Year(s) Of Engagement Activity 2017
 
Description The Dairy Council Conference 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Type Of Presentation keynote/invited speaker
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Talk sparked questions and discussion afterwards
The Dairy Council: Dairy Makes a Difference to Diet and Sustainability Talk Title: Overview of University of Reading research on dairy foods and health Welcome & Introduction: Global overview of attitudes and initiatives Dr Judith Bryans - Dairy UK Session 1: Dairy sustainability - what the data tell us - chaired by Dr Anne Mullen · Dealing with trade-offs - Ray Keatinge, DairyCo. · Overview of University of Reading research on dairy foods and health - Professor Ian Givens, The University of Reading · Dairy and cardiovascular disease risk - Professor Julie Lovegrove, The University of Reading · Dietary patterns associated with UK dairy intake - Dr Ditte Hobbs, The University of Reading · Environmental impact - John Elliott, ADAS Session 2: Dairy sustainability - industry response to the challenges - chaired by Dr Anne Mullen · Global Dairy Sustainability Framework - Brian Lindsay, GDAA · UK Farming Sector Initiatives & Dairy Roadmap - Ray Keatinge, DairyCo. · UK Processing Sector Initiatives - Richard Laxton, Arla Foods · Dairy UK Initiatives - Joanna Stewart, Dairy UK · Panel discussion - chaired by Duncan Pullar · Closing Remarks: summation and where next? - Duncan Pullar, DairyCo. Project Overview The FAO defines a sustainable diet as one that has a low environmental impact yet contributes to food and nutrition security and to a healthy life for present and future generations. Sustainable diets should be respectful of biodiversity and ecosystems and be culturally acceptable, accessible, economically fair and affordable, nutritionally adequate, safe and healthy - whilst optimising natural and human resources. Identifying trade-offs in production of nutritious, affordable food and the impact of this on the environment is a key challenge for the dairy industry. In the UK, there are excellent existing methodologies for measuring the impact of dairy farming on the environment, for measuring the financial cost and the nutrition quality of the UK diet. DairyCo, Dairy UK and The Dairy Council commissioned a project with the University of Reading - collaborating with ADAS & RAND Europe to, in Phase 1, critically evaluate existing methodologies for the measure of environmental impact, financial cost and nutrient quality of diets in the UK, and, in Phase 2, to harness these into a model that can simultaneously evaluate all elements of the FAO's definition of sustainable diet. Phase 1 is now complete. Phase 2 will be completed in March 2015. Conference Overview Academics, industry representatives and NGOs gathered in London to hear from a panel of experts who explored the progress and the challenges associated with the production of nutritious and sustainable products. Dr Judith Bryans, Chief Executive of Dairy UK, set the scene by reminding the audience that with current changes in world demographics the need to produce an increasing amount of food sustainably for a growing world population is greater than ever. Ray Keatinge, Head of Research and Development at DairyCo, overviewed the trade-offs in food production and environmental sustainability, presenting the challenges in a realistic and pragmatic manner. A key message of the conference was that a sustainable diet is not just one that has a low environmental impact, but also one that contributes to optimal nutrition and to a healthy lifestyle. Professor Ian Givens and Professor Julie Lovegrove, Professors of Food Chain Nutrition and Human Nutrition respectively at the University of Reading, presented evidence around consumption of dairy and human health. Professor Lovegrove pointed out that, although dairy products make a contribution to the nation's intake of saturated fat, research currently indicates that dairy products appear to decrease the risk of heart disease. Professor Givens commented that dairy products also contain a number of nutrients which have been shown to benefit other areas of health (e.g. bone health and foetal cognitive development).This highlights the importance of developing nutritional recommendations based on entire foods rather than on single nutrients. Dr Ditte Hobbs, Post-Doctoral Research Fellow in the Department of Food and Nutritional Sciences at the University of Reading, presented the project she is currently working on with ADAS and RAND Europe. This project involves modelling the impact of different levels of dairy consumption on affordability, nutritional adequacy and environmental impact of the entire diet. Preliminary results have found that people who consume dairy tend to have generally healthier diets (see News In Brief). The environmental indicators used in the project were explored by John Elliott, Senior Agricultural Economist at ADAS, and include greenhouse gas emissions, water utilisation and biodiversity impacts. Data will follow impacts from cradle to point of purchase and will also account for waste. Ray Keatinge commented that complex interactions are involved and that it is important to bear in mind that different agricultural methods may affect different sustainability factors (e.g. greenhouse gas emissions, energy use, biodiversity and water use). Going forward, DairyCo, Dairy UK and The Dairy Council will continue to invest in research and the implementation of industry-wide strategies to support sustainable dairy production in the UK. Brian Lindsay, Development Director for the Dairy Sustainability Framework, explained the remit of the Framework which sets environmental targets for companies worldwide and develops commitment plans to achieve the preservation of natural resources. Examples of UK farming initiatives were presented by Ray Keatinge, Head of Research and Development at DairyCo, and include the DairyCo carbon foot printing project which uses strategies such as improved energy efficiency, uptake of renewable energy and innovative feeding systems. Mr Keatinge also gave an overview of the Dairy Roadmap, which sets producer and processor targets for several items including sustainable energy and water use. Richard Laxton, Global Sustainability Manager at Arla Foods, described current dairy processing initiatives. These involve reducing the amount of carbon emissions and using water and energy in a sustainable way. He offered examples of ground-breaking innovations, such as DairyCrest Davidstow's biomass steam plant and Muller Wiseman's heat pumps which divert heat previously dispersed through cooling towers towards pasteurisation. Concluding this session, Joanna Stewart, Dairy UK's Environment Manager, gave an overview of Dairy UK initiatives, such as the Environmental Benchmarking Tool which helps member companies monitor and improve their environmental performance as well as the Global Benchmarking Project to compare the UK's performance to that of other countries.

To be added
Year(s) Of Engagement Activity 2014
URL http://www.milk.co.uk/page.aspx?intpageid=473
 
Description The importance of milk in the diets of infants, pregnant women, adolescents and adults 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact My presentation was an invited one at the 2019 Annual Meeting of the American Dairy Science Association in Cincinnati. It was part of a special session organised by the University of Florida and related to their USAid grant aimed at reducing stunting in children in Africa. My talk covered :The different life stages give rise to important nutritional challenges some of which are related to increasingly aged populations in many Western societies. There is however, increasing evidence that diets during childhood and adolescence can impact on health in later adulthood. For example, undernutrition in childhood can lead to stunted growth which is associated with reduced cognitive ability and increased risk of chronic diseases and co-morbidities in adulthood. Despite recent worldwide improvements, stunting in sub-Saharan Africa remains about 40 % and some countries have an even higher prevalence. Milk is a key food for reducing stunting with milk proteins having a crucial role.
Year(s) Of Engagement Activity 2019
URL https://www.adsa.org/Meetings/2019-Annual-Meeting
 
Description The role of dairy foods in the diet of children and adolescents? 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact My presentation was an invited one at the 2019 Excellence in Pediatrics Congress held in Copenhagen in December 2019. The event was primarily for pediatricians with an input from other related specialists such as in childhood allergy. Broadly my presentation covered: The different life stages give rise to important nutritional challenges some of which are related to increasingly aged populations in many Western societies. There is however, increasing evidence that diets during childhood and adolescence can impact on health in later adulthood.
Year(s) Of Engagement Activity 2019
URL https://d3n8a8pro7vhmx.cloudfront.net/ineip/pages/3076/attachments/original/1576137688/EIP2019_Confe...
 
Description The role of milk and dairy in the diet from childhood to old age 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact My presentation was an invited one at the 22nd Nutrition and Health Congress held in Brussels in November 2019. The large audience was dominated by clinicians and dietitians. My talk covered: Despite an ongoing increase in life expectancy, it is not always accompanied by an increase in healthy lifespan. There is increasing evidence that dietary exposure in early life can substantially impact on chronic disease risk in later life. Milk and dairy foods are nutrient dense foods and important suppliers of a range of key nutrients with some being particularly important at certain life stages.
Year(s) Of Engagement Activity 2019
URL https://10times.com/nutrition-and-health
 
Description University of Milan ASPA Conference, 2015 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Dairy foods, dietary partners for life? Participants: Scientists, health professionals from around the EU.
Year(s) Of Engagement Activity 2015
 
Description University of Reading Agriculture and Food Investigation Team national event, Reading, 2016 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact University of Reading Agriculture and Food Investigation Team national event. Title of talk: Milk and dairy: Dietary partners for life? Participants: Agriculture and food economists from around the UK who are involved in farm management data analysis for DEFRA, DEFRA staff.
Year(s) Of Engagement Activity 2016
 
Description Visit from the Fonterra Co-operative Group Ltd (New Zealand)- Reading, UK 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact During this meeting, awareness was raised about our MRC project and a link was established with a leading multinational dairy company.

Fonterra acknowledged the strength that the University of Reading (including the MRC funded project) might bring to a future strategic research partnership.
Year(s) Of Engagement Activity 2014
 
Description Work featured in ITV's Tonight programme Fat: The Healthy Option? 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Work featured in ITV's Tonight programme Fat: The Healthy Option? This involved a discussion on types of fat and their relative effects on cardiovascular disease including the effects of the dairy food matrix in certain foods and how these can modify the body's metabolic response to dietary fat, including saturated fat.
Year(s) Of Engagement Activity 2017
 
Description Workshop on Milk, nutritional quality, and cardiometabolic health, Paris, 2015 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Review of effects of dairy foods on cardiometabolic health. Participants: Members of the International Chair on Cardiometabolic Health plus scientists from various parts of the world.
This has led to the publication of a paper: Canadian Journal of Cardiology doi: 10.1016/j.cjca.2015.12.03
Year(s) Of Engagement Activity 2014
 
Description a Fellowship Inaugural talk at Loughborough University entitled: Can changing the fat composition of the diet reduce cardiometabolic disease risk? RESET was featured-Dr Oonagh Markey 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Included RESET as part of the research experience of Dr Oonagh Markey.
Year(s) Of Engagement Activity 2018