The MRC ConDuCT-II Hub. COllaboration and iNnovation in DiffiUlt and Complex randomised controlled Trials In Invasive procedures
Lead Research Organisation:
University of Bristol
Department Name: Social Medicine
Abstract
The ConDuCT-II Hub is based within the School of Social and Community Medicine, at the University of Bristol and is led by Professor Blazeby, Professor of Surgery. It will include a multi-disciplinary group of academics with established track records in the development of better ways for designing and conducting research to evaluate healthcare interventions. The work will focus on creating new methods and improving existing methods to undertake randomised controlled trials. Randomised controlled trials usually compare two new or standard treatments. The importance of a randomised controlled trial is that patients participating in them could be allocated to either of the procedures under evaluation by a process of randomisation. This means that the patients have an equal chance of having either procedure and so a fair comparison of the outcomes of each of them can be made. These types of studies are the most valid and reliable means of evaluating healthcare interventions, and there is a need for better ways of conducting the trials to inform health policy and practice. There is a particular lack of well designed and conducted randomised controlled trials in surgery and invasive healthcare procedures which means that practice is not based on evidence and standards of surgery and similar invasive procedures vary across the country and within the NHS.
The research will be undertaken by four interlinked themes. The themes include: (1) trial prioritisation and design, (2) trial recruitment, (3) feasibility study design and trial conduct, and, (4) outcome assessment, reporting and integration into decision-making. Each theme is underpinned by expertise in statistics and qualitative methods and there are close links to practising clinicians and the two clinical trials units in Bristol, the Bristol Randomised Trials Collaboration and the Clinical Trials and Evaluation Unit. The Hub has additional collaborations with the regional and national registered clinical trials units and other MRC Hubs. The ConDuCT-II Hub will build on these relationships and with new relationships with the Royal College of Surgeons of England Surgical Trials Centres (in Bristol, Oxford, Birmingham and Manchester/Liverpool). The ConDuCT-II Hub will also develop international links to surgeons and methodologists worldwide by providing innovative methods to optimise the conduct of trials in surgery and by provision of specialist training. The ConDuCT-II Hub will undertake methodological research and it will integrate innovative methods into new feasibility studies and full trials in surgery and invasive procedures.
The ConDuCT-II Hub will also deliver a training programme for clinicians and other scientists in study design and methods to optimise the design and delivery of complex healthcare interventions and trials in surgery. These courses will also be relevant to trials of public healthcare and primary care interventions. These are similar to surgical interventions because they include multiple components within each intervention, that influence outcomes by acting both together and separately. The training programme will provide an apprenticeship to create a new generation of clinicians who understand and practice evidence based medicine. The new methods will be implemented in new trials and this will lead to evidence to inform healthcare decision-making at policy and practice level. It is anticipated that the ConDuCT-II Hub will ultimately lead to a sustainable change in research culture and it will allow more and even better trials to be developed to answer critical questions of relevance to patients and the NHS.
The research will be undertaken by four interlinked themes. The themes include: (1) trial prioritisation and design, (2) trial recruitment, (3) feasibility study design and trial conduct, and, (4) outcome assessment, reporting and integration into decision-making. Each theme is underpinned by expertise in statistics and qualitative methods and there are close links to practising clinicians and the two clinical trials units in Bristol, the Bristol Randomised Trials Collaboration and the Clinical Trials and Evaluation Unit. The Hub has additional collaborations with the regional and national registered clinical trials units and other MRC Hubs. The ConDuCT-II Hub will build on these relationships and with new relationships with the Royal College of Surgeons of England Surgical Trials Centres (in Bristol, Oxford, Birmingham and Manchester/Liverpool). The ConDuCT-II Hub will also develop international links to surgeons and methodologists worldwide by providing innovative methods to optimise the conduct of trials in surgery and by provision of specialist training. The ConDuCT-II Hub will undertake methodological research and it will integrate innovative methods into new feasibility studies and full trials in surgery and invasive procedures.
The ConDuCT-II Hub will also deliver a training programme for clinicians and other scientists in study design and methods to optimise the design and delivery of complex healthcare interventions and trials in surgery. These courses will also be relevant to trials of public healthcare and primary care interventions. These are similar to surgical interventions because they include multiple components within each intervention, that influence outcomes by acting both together and separately. The training programme will provide an apprenticeship to create a new generation of clinicians who understand and practice evidence based medicine. The new methods will be implemented in new trials and this will lead to evidence to inform healthcare decision-making at policy and practice level. It is anticipated that the ConDuCT-II Hub will ultimately lead to a sustainable change in research culture and it will allow more and even better trials to be developed to answer critical questions of relevance to patients and the NHS.
Technical Summary
The ConDuCT-II Hub is based within the School of Social and Community Medicine, at the University of Bristol and led by Blazeby, Professor of Surgery. It will build on the achievements of the ConDuCT Hub to develop the Hub into a world class centre of excellence for high-quality, cutting-edge methodological research of relevance to pragmatic randomised controlled trials (RCTs) in general, but with a particular focus on the needs of RCTs in surgery. Within the Hub there will be four interlinked research themes. The themes include: (1) trial prioritisation and design, (2) trial recruitment, (3) feasibility study design and trial conduct, and, (4) outcome assessment, reporting and integration into decision-making. Each theme is underpinned by expertise in statistics and qualitative methods and there are close links to practising clinicians and the two registered clinical trials units (CTUs) in Bristol. The Hub has regional and national collaborations with other registered CTU and MRC Hubs and it will develop new relationships with the Royal College of Surgeons of England Surgical Trials Centres and international collaborations with surgical trials centres in continental Europe and North America by providing innovative methods to optimise the conduct of trials in surgery and by provision of specialist training. The Hub will deliver a training programme for clinicians and methodologists in specialists areas to optimise the design and delivery of complex healthcare interventions and trials in surgery. The Hub will integrate new and improved methods into new trials in collaboration with regional and national CTUs working closely with clinicians (especially surgeons). The combination of new methods, training courses, workshops and apprenticeship opportunities offered by the Hub will lead to more and better trials to be developed to answer critical questions of relevance to patients and the NHS.
Planned Impact
The research, training and work undertaken by the ConDuCT-II Hub will impact policy makers, health care innovators, scientists nationally and internationally, clinicians and patients. The Hub will develop and improve methods to undertake randomised controlled trials (RCTs) that will lead to marked improvements in the successful design, conduct and completion of pragmatic RCTs in all areas but particularly in surgery.
Policy makers (such as the National Institute for Heath and Clinical Excellence, NICE) will benefit because the Hub will carry out methodological research to improve the commissioning, design and conduct of RCTs of non-pharmaceutical and invasive interventions. Currently the NICE Interventional Procedures Committee reviews selected invasive procedures and makes recommendations on uptake but it is often limited by the lack of high quality RCTs in this area. The Hub, therefore, by improving the number and quality of trials will directly provide evidence for review by this committee.
The Hub will also impact on clinicians who develop innovative practice in complex non-pharmaceutical interventions. Currently this is performed within strict regulations which is risky and is likely to have led to the introduction of interventions into clinical practice which are at best an ineffective and inefficient use of resources and at worst could have serious but unrecognised side effects. In the ConDuCT-II hub new methods will be developed to study complex invasive healthcare interventions and to introduce them into practice. It will impact on clinicians by working with them to gain funding to allow safe and more controlled evaluations of new interventions. Similarly work in the Hub will impact on clinical trialists in the UK and internationally who will use the methods and implement them into new studies.
A major theme in the Hub will focus upon methods to improve the selection and implementation of outcomes in trials. The Hub will develop methods to improve the content and validity of 'core outcome sets'. The use of core outcome sets will impact several key stakeholders because it will allow data synthesis from trials to inform policy makers (e.g. NICE) and scientists (e.g. in meta-analyses) and importantly it will provide the core information for clinicians to communicate to patients regarding the trial results. In ConDuCT-II methods for clinicians to communicate the core information will be developed and tested. This will improve health professionals' satisfaction with the consultation process and it is expected that better information provision will reduce litigation and complaints and more satisfied patients.
The ConDuCT-II will also impact by its training courses on clinicians and trainees and methodologists. The courses will focus on best methodologies for RCTs of non-pharmaceutical interventions, and especially surgery. This will build future capacity through training methodologists and clinicians via new short courses and provision of both clinical and non-clinical PhD studentships. Up to five clinicians will have the opportunity for a clinical research taster for six months within the Hub during which they will be supported to develop and write a full research training fellowship application. The methodologically trained clinicians will then become future leaders and academics in this field to pursue the vision of the Hub and change the culture in surgery such that practice can become based on evidence and so standards of care across the UK can be developed.
Policy makers (such as the National Institute for Heath and Clinical Excellence, NICE) will benefit because the Hub will carry out methodological research to improve the commissioning, design and conduct of RCTs of non-pharmaceutical and invasive interventions. Currently the NICE Interventional Procedures Committee reviews selected invasive procedures and makes recommendations on uptake but it is often limited by the lack of high quality RCTs in this area. The Hub, therefore, by improving the number and quality of trials will directly provide evidence for review by this committee.
The Hub will also impact on clinicians who develop innovative practice in complex non-pharmaceutical interventions. Currently this is performed within strict regulations which is risky and is likely to have led to the introduction of interventions into clinical practice which are at best an ineffective and inefficient use of resources and at worst could have serious but unrecognised side effects. In the ConDuCT-II hub new methods will be developed to study complex invasive healthcare interventions and to introduce them into practice. It will impact on clinicians by working with them to gain funding to allow safe and more controlled evaluations of new interventions. Similarly work in the Hub will impact on clinical trialists in the UK and internationally who will use the methods and implement them into new studies.
A major theme in the Hub will focus upon methods to improve the selection and implementation of outcomes in trials. The Hub will develop methods to improve the content and validity of 'core outcome sets'. The use of core outcome sets will impact several key stakeholders because it will allow data synthesis from trials to inform policy makers (e.g. NICE) and scientists (e.g. in meta-analyses) and importantly it will provide the core information for clinicians to communicate to patients regarding the trial results. In ConDuCT-II methods for clinicians to communicate the core information will be developed and tested. This will improve health professionals' satisfaction with the consultation process and it is expected that better information provision will reduce litigation and complaints and more satisfied patients.
The ConDuCT-II will also impact by its training courses on clinicians and trainees and methodologists. The courses will focus on best methodologies for RCTs of non-pharmaceutical interventions, and especially surgery. This will build future capacity through training methodologists and clinicians via new short courses and provision of both clinical and non-clinical PhD studentships. Up to five clinicians will have the opportunity for a clinical research taster for six months within the Hub during which they will be supported to develop and write a full research training fellowship application. The methodologically trained clinicians will then become future leaders and academics in this field to pursue the vision of the Hub and change the culture in surgery such that practice can become based on evidence and so standards of care across the UK can be developed.
Organisations
- University of Bristol, United Kingdom (Collaboration, Lead Research Organisation)
- NIHR London (South) CRN (Collaboration)
- University of Edinburgh, United Kingdom (Collaboration)
- University of Gothenburg, Sweden (Collaboration)
- NHS Bristol CCG (Collaboration)
- Mount Vernon Hospital (Collaboration)
- Newcastle University, United Kingdom (Collaboration)
- Royal Devon and Exeter NHS Foundation Trust (Collaboration)
- Sue Jenkins & Associates (Collaboration)
- University of Saskatchewan, Canada (Collaboration)
- University of Liverpool, United Kingdom (Collaboration)
- University of Cambridge (Collaboration)
- Nottingham Uni Hospitals NHS Trust, United Kingdom (Collaboration)
- University of Stirling, United Kingdom (Collaboration)
- European Commission, Belgium (Collaboration)
- Arthritis Care Scotland (Collaboration)
- University of Oxford, United Kingdom (Collaboration)
- Hub at the MRC/CRUK/BHF Clinical Trial Service Unit (Collaboration)
- Wiltshire Council, United Kingdom (Collaboration)
- King Edward Memorial Hospital (Collaboration)
- National University of Ireland, Galway (Collaboration)
- Liverpool Heart and Chest Hospital NHS Foundation Trust (Collaboration)
- Maastricht University (UM) (Collaboration)
- Ontario Institute for Cancer Research, Canada (Collaboration)
- University of Glasgow, United Kingdom (Collaboration)
- University of East Anglia, United Kingdom (Collaboration)
- University of the West of England, United Kingdom (Collaboration)
- University of Birmingham, United Kingdom (Collaboration)
- University of Exeter, United Kingdom (Collaboration)
- Wrightington, Wigan and Leigh NHS Foundation Trust (Collaboration)
- The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust (Collaboration)
- University of Aberdeen, United Kingdom (Collaboration)
- Pfizer Ltd (Collaboration)
- BUPA (Collaboration)
- Patient-Centered Outcomes Research Institute (Collaboration)
- University of Pittsburgh (Collaboration)
- University of Leicester, United Kingdom (Collaboration)
- King's College London, United Kingdom (Collaboration)
- University of Southampton, United Kingdom (Collaboration)
- North Somerset Council (Collaboration)
- University College London, United Kingdom (Collaboration)
- North Bristol Nhs Trust, United Kingdom (Collaboration)
- University Hospitals Birmingham NHS Foundation Trust, Birmingham (Collaboration)
- University of Bath, Bath (Collaboration)
- Royal College of Surgeons of England, United Kingdom (Collaboration)
- Bangor University, United Kingdom (Collaboration)
- Oxford University Hospitals NHS Foundation Trust, Headington (Collaboration)
- Queen Mary, University of London, United Kingdom (Collaboration)
- Institute of Cancer Research UK (Collaboration)
- Cardiff University, United Kingdom (Collaboration)
- Great Ormond Street Hospital (GOSH) (Collaboration)
- University of Sheffield, United Kingdom (Collaboration)
- University of Alberta (Collaboration)
- Leeds Teaching Hospitals NHS Trust, United Kingdom (Collaboration)
- McMaster University, Canada (Collaboration)
- Frome Valley Health Ltd (Collaboration)
- University of Warwick, United Kingdom (Collaboration)
- St George's University Hospitals NHS Foundation Trust (Collaboration)
- Cardiff & Vale University Health Board, United Kingdom (Collaboration)
- Cambridge University Hospitals, Cambridge (Collaboration)
- Queen's University of Belfast, United Kingdom (Collaboration)
- University of York, United Kingdom (Collaboration)
- Medical Research Council (Collaboration)
- Royal Brompton & Harefield NHS Foundation Trust (Collaboration)
- University of Leeds, United Kingdom (Collaboration)
- Deltahat Consulting (Collaboration)
- Swansea University, United Kingdom (Collaboration)
- Alder Hey Children's NHS Foundation Trust (Collaboration)
- Radboud University Nijmegen, Netherlands (Collaboration)
- Northwest Research Collaborative (Collaboration)
- University of Manchester, Manchester, United Kingdom (Collaboration)
- National University of Ireland Galway, Ireland (Collaboration)
- Sheffield Teaching Hospitals NHS Foundation Trust (Collaboration)
Publications
Al-Janabi H
(2015)
Test-retest reliability of capability measurement in the UK general population.
in Health economics
Al-Janabi H
(2016)
Measuring Health Spillovers for Economic Evaluation: A Case Study in Meningitis.
in Health economics
Al-Janabi H
(2016)
A Framework for Including Family Health Spillovers in Economic Evaluation.
in Medical decision making : an international journal of the Society for Medical Decision Making
Alfirevic Z
(2015)
Labour induction with prostaglandins: a systematic review and network meta-analysis.
in BMJ (Clinical research ed.)
Alfirevic Z
(2016)
Methods to induce labour: a systematic review, network meta-analysis and cost-effectiveness analysis.
in BJOG : an international journal of obstetrics and gynaecology
Alfirevic Z
(2016)
Which method is best for the induction of labour? A systematic review, network meta-analysis and cost-effectiveness analysis.
in Health technology assessment (Winchester, England)
| Title | Investigating the effect of treatment preferences on recruitment and retention to paediatric trials. |
| Description | Poster produced by Beasant for Research without Borders Exhibition, Bristol. The primary audience were students and the geographical reach was local. |
| Type Of Art | Artwork |
| Year Produced | 2016 |
| Impact | Not aware of any |
| Title | OPTIMA (Optimal Personalised Treatment of early breast cancer using Multi-parameter Analysis): A prospective trial to validate the predictive utility and cost-effectiveness of gene expression test-directed chemotherapy decisions |
| Description | Francis, Adele; Stein, Robert C.; Marshall, Andrea; Rea, Daniel W.; Cameron, David A.; Macpherson, Iain R.; Earl, Helena M.; Poole, Christopher J.; Hall, Peter S.; Bartlett, John M.S.; Rooshenas, Leila; Morgan, Adrienne; Harmer, Victoria; Donovan, Jenny; Hulme, Claire; McCabe, Christopher; Pinder, Sarah E.; Hughes-Davies, Luke; Makris, Andreas; Dunn, Janet A. Poster presented for Association of Breast Surgery (abstract published in: European Journal of Surgical Oncology, Vol. 42, No. 5, 09.04.2016, p. S9-S10.) in Manchester. The primary audience were professional practitioners and the geographical reach was national. |
| Type Of Art | Image |
| Year Produced | 2016 |
| Impact | Not aware of any |
| Title | The treatment preferences of adolescents and their parents, what has the smile RCT shown us? SMILE: specialist medical intervention and lightning evaluation |
| Description | A poster produced by Beasant, L, Mills, N. & Crawley, E. for the 3rd International Clinical Trials Methodology Conference & Trials. 2015 in Glasgow. The primary audience were professional practitioners and the geographical reach was national. |
| Type Of Art | Artwork |
| Year Produced | 2015 |
| Impact | Not aware of any |
| Description | Abstract Committee, Cochrane abstract committee |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Advice to HRB-TMRN QUESTS team Steering Committee - Julia Wade |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Description | Advice to HRB-TMRN QUESTS team regarding their project on the development and evaluation of a RCT recruiter training intervention |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Advice to ZonMW (Netherlands Organisation for Health Research and Development), Den Haag, Netherlands on recruitment to trials - Jenny Donovan |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Advisory Committee QUESTS - Care Clement |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Advisory committee: Designing a service model to promote the mental health and well-being of children in Cambridgeshire and the East of England |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in advisory committee |
| Description | Amber Young Appointed as trustee to Childrens Burns Trust |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Association of Breast Surgery Academic and Research Committee - Shelley Potter |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Awards Committee, Cochrane Thomas Chalmers Awards committee |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Chair TSG - REACH Pregnancy Programme |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Chair of Advisory Group - MRC/NIHR Methodology Research Programme |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Chris Rogers member of steering committee - Health Foundation |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Chris Rogers, Oversight committee, DMC, NIHR HTA |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Citation of co-authored paper [Hopkins et al, 2015] in systematic review |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in systematic reviews |
| Description | Citation of first author paper [Coulman et al, 2013] in three systematic reviews |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Citation in systematic reviews |
| Description | Co-Director |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Cochrane Multiple Interventions Group |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Cochrane Scientific Committee |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Cochrane Trainees, Committee member, Natalie Blencowe |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a advisory committee |
| Description | Committee member, Diabetes UK Clinical Studies Group |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | DMC Chair: Women Offenders Repeat Self-Harm Intervention |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | DMC, Trial Governance, IntAct:Intraoperative Fluorescence sngiography to prevent colorectal anastomotic leak |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | DMC, Trial Governance, Minimally invasive thoracoscopically-guided right minithoracotomy versus conventional sternotomy for mitral valve repair: a multicentre randomised controlled trial (UK Mini Mitral) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | DMC: Scandinavian Prostate Cancer Group Trial #17: Prostate Cancer Active Surveillance Trigger Trial (PCASTT), |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Data Monitoring Committee - LORIS Trial |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Data Monitoring Committee - PD_STAT study |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Data Monitoring Committee - TOPPOTS trial |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Director for the NICE Clinical Guidelines Technical Support Unit |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Editorial Board Member - Health Expectations Editorial |
| Geographic Reach | National |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| Description | Editorial Board of the NIHR Trial Managers network Trial Mangement Guide |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guidance committee |
| Impact | This group prepared the 'Guide to Efficient Trial Management' 2014. Impact is projected/expected. " (Athene Lane) |
| URL | http://www.nihr.ac.uk/documents/about-NIHR/NIHR-Publications/Trial-managers-network-guidelines.pdf |
| Description | Education Committee of the 4th International Clinical Trials Methodology Conference and the Society for Clinical Trials 38th Annual Meeting |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Elliott D, Lead facilitator, MRC HTMR Recruitment Working group |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Expert Advisory Group member for the Irish Health Information and Quality Authority (HIQA) Health Technology Assessment of Smoking Cessation Interventions |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Expert Panel - NCRI Future of Surgery |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Governance Committee |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Grant Committee |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Grant Committee - Bowel Cancer UK grant committee |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant Committee - NIHR HTA Comissioning Board |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Grant Committee - NIHR Health Services and Delivery Research Committee |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant Committee - NIHR Public Health Research Board |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant Committee - NIHR RfPB South West |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant Committee - PHIND |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant Committee - RfPB SW Panel member |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant Committee, Medical Research Council (MRC) Clinical Training and Career Development Panel, Jane Blazeby |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant Committee, NIHR Fellowship Programme Reviews Panel for Career Development, Senior and Transitional Research Fellowships, Jane Blazeby |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant Committee, NIHR Senior Investigator Appointment Panel |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant Committee, NIHR-HTA, Chris Rogers |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant Committee, Ordinary member of the Executive Committee of the International Society of Clinical Biostatistics |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Description | Grant committee - NIHR Research Methods Funding Board |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Grant committee, MRC Public Health Intervention Development (PHIND) Scheme Funding Board |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant committee, Member of the NIHR Clinical Trials Units Standing Advisory Committee |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant committee, Member, South West Region Advisory Committee for the NHS Research for Patient Benefit (RfPB) funding scheme |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant committee, NIHR Research Methods Fellowships and Internships Expert Review Panel member |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant committee, NIHR Research Methods Fellowships and Internships and NIHR Systematic Review Fellowships |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant committee, Society of Clinical Trials Board nominating committee, Jane Blazeby |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant committee, South West RfPB |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant committee, Trials Methodology Research Network Studies within a Trial Call 2016, Irish Health Research Board |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Grant reviewing |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Honorary consultant contract {Public Health England - Rona Campbell |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | ICTMC Scientific Committee 2019 - Will Hollingworth |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | ICTMC Scientific Committee 2019 - abstract reviewer - Nicola Mills |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | InterTASC workshop presentation (N Welton) |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Invited researcher, consensus workshop (funding agency) NIHR CRN Specialty cluster - Talia Isaacs |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | JB - Dragon's Den at AUGIS Annual Scientific Meeting this year - training event for surgical trials. |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| URL | http://www.augis.org.uk/brighton2014/ |
| Description | JB on TSC - UKUFF TSC - meeting on 14/05/14 |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guidance committee |
| URL | https://viis.abdn.ac.uk/HSRU/UKUFF/Site/Public/Default.aspx |
| Description | Kerry Avery - member of formal working group, otcomes working group for new MRC Trials Methodology Research Partnership |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Knowledge Gaps in Oncoplastic Breast Surgery, Oncoplastic Breast Surgery Consortium Consensus Conference - Shelley Potter |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Description | MAST - Clinician |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | MAST - DISC RCT |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a advisory committee |
| Description | MAST - DISC RCT |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a advisory committee |
| Description | MAST - Sabine van der Veer |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | MAST, Karen Spencer (Univeristy of Manchester) |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a advisory committee |
| Description | MAST, MRC HTMR Trial Conduct Working Group member, Athene Lane |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | MAST, Requested training/advice on improving recruitment to difficult RCT, Tim Davis (Queen's Medical Centre, Nottingham) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | MAST, Trial Conduct Working Group member, Clare Clement |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | MAST: Qualitative advice given to Oxford team developing grant application for a trial of different surgical co-interventions for brain tumour resection. |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | MRC Hubs for Trials Methodology Network |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Member MRC-NIHR Methodology Advisory Group - Jenny Donovan |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Member TSG - Healthy Dads, Healthy Kids UK |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Member and Chair of Expert Panel - DIFA |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Member of British Journal of Surgery Council |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Member of Consensus Group - MRC/NIHR Methodology Reseacrch Programme Exploratory Trials Guidance |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Description | Member of MRC HTMR Network Summit and Expert Panel on the integration of quantitative and qualitative data findings in clinical trials |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Member of NIHR Senior Investigators Appointment panel |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Member of Research Advisory panel - Macmillan Cancer Support |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Member of TSG. Project on development and evaluation of an RCT recruiter training intervention |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Member of Trial Steering Committee: SPRING (PI Robin Grant, NIHR HTA) |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Member of UKCRC clinical trial units network Core Infrastructure & Resources task and finish group |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | NICE Service Guidance Methods Expert Working Group |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | NICE Technology Appraisals Cancer Drugs Fund Committee |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | NIHR CLAHRC West Research Advisory Panel, Chair, Tim Peters |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a advisory committee |
| Description | NIHR Complex Reviews Support Unit Advisory/Governance Committee |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | NIHR Fellowship Programme Review Panel for Career Development, Senior Research and Transitional Research Fellowships |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | NIHR HTA - Nicola Mills |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | NIHR Senior Investigator Committee |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | NIHR research - Making the most of your methodologists |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Nicola Mills, MAST, Advice on publication and consideration of further data collection |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Nicola Mills, MAST, Advice on qualitative methodology within an RCT |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Nicola Mills, MAST, Advice on recruiting patients to surgical trials |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Nicola Mills, MAST, Advice on training recruiters to research studies |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Overall project lead and lead of the randomisation methods working group. |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Oversight Committee, Data Monitoring Committee, NIHR-HTA funded UK Mini Mitral, Chris Rogers |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Oversight Group of the NIHR Trial Managers Network: 2011-2014 |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guidance committee |
| Description | Pat Hoddinott, Chair of TSC, NIHR HTA16/143/01- FROSTTIE: A randomized controlled trial of FRenotomy and breastfeeding support Or breastfeeding Support without frenotomy to investigate continuation of breastfeeding for babies with Tongue TIE. |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Pat Hoddinott, grant funding committee, HTA Commissioning Board |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Pat Hodinott, member of TSC, Evaluation of the outcomes of the Family Nurse partnership Programme in Scotland. . Funded by Scottish Government. |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | PhD external examiner |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Reproduction of 'Distress Thermometer and Problem List |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Research Committee member, Vascular Society if Great Britain & Ireland |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Research Committee of the 4th International Clinical Trials Methodology Conference and the Society for Clinical Trials 38th Annual Meeting |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Rhiannon Macefield, member of formal working group, National Wound Care Strategy Programme - member of the surgical workstream and and research enabler workstream |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Rooshenas L, Jepson M, Paramasivan S, Other, Advice on recruitment feedback session for RADAR trial RADAR NIHR HTA |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a advisory committee |
| Description | SCREESCO Trial Steering Committee |
| Geographic Reach | Europe |
| Policy Influence Type | Participation in a advisory committee |
| Description | Sangeetha Paramasivan, MAST, Advice and potential involvement from a Methodology and QoL perspective for a proposed breast implant RCT |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Sangeetha Paramasivan, MAST. Request for potential collaborators for a HTMR proposal on ethnic minority groups' understanding of patient information leaflets |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Scientific Committee |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Scientific Committee member - Wounds Research Network (WReN) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Scientific Programme Committee - ISCBC |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Scientific reference group to the NHS Prostate Cancer Risk Management programme. AL |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guidance committee |
| Description | Society of Clinical Trials Membership Committee - Athene Lane |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Steering group member NCRI-NIHR Future Leaders - Angus McNair |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Summit and Expert Panel on mixed Methods - MRC HTMR Hubs Network |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | TSC Chair |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | TSC Chair, MACRO: Defining best management for adults with chronic rhinosinusitis. NIHR Programme Grants for Applied Research (PGfAR) RP-PG-0614-20011 |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | TSC Chair, PARCS: Patch Augmented Rotator Cuff Surgery Study- A feasibility study. NIHR HTA Programme |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | TSC Chair, Trial Governance, GAPS Trial |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | TSC Chair, Trial Governance, LaCes feasibility: A multicentre, randomised controlled feasibility trial of laparoscopic versus open colorectal surgery in the acute setting. NIHR RfPB |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | TSC Chair, Trial Governance, PulMiCC Trial |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | TSC member, Trial Governance, A realist process evaluation of robotic surgery. NHS NIHR, Health Services and Delivery Research programme |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | TSC member, Trial Governance, MIDFUT Trial |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial Govenance, Trial Steering Committee, Hughes Abdominal Repair Trial (PI Jared Torkington, NIHR HTA) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial Governance, Clinical and cost-effectiveness of progressive exercise compared to best practice advice, with or without corticosteroid injection, for the treatment of rotator cuff disorders: a 2x2 factorial randomised controlled trial (The GRASP trial) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Trial Governance, Trial Steering Committee, PACE trial (PI Chris Butler, NIHR HTA) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial Governance: PARCS: Patch Augmented Rotator Cuff Surgery Study- A feasibility study. |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial Governance: Thermal Abalation versus surgery for patients with colorectal liver metastases. The LAVA trial |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial Management Group: SMALL |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Trial Management Working Group (co-lead) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial Steering Committee - BRAVO study |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial Steering Committee - HALT-IT |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial Steering Committee - the GRASP Trial |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial Steering Committee, DISCHARGE (PI Marc Dewey, EU FP7) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial Steering committee, OPTCARE Neuro (PI Irene Higginson, NIHR HS & DS) |
| Geographic Reach | South America |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial governance committee, Data Monitoring Committee, NIHR-EME funded IntAct trial, Chris Rogers |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial governance, High risk bladder cancer: A randomised controlled feasibility study of radical cystectomy against intra-vesical immunotherapy (BRAVO) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Trial governance, Nicola Wiles, Data Monitoring Committee, NIHR HTA funded VIP trial (PI: M Serfaty, UCL) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial governance, Nicola Wiles, Trial Steering Committee, NIHR HTA funded TOSCA trial (PI: Buszewicz, UCL) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial governance, SCREESCO, a Swedish National trial, funded by government, of the cost-effectiveness of colorectal cancer screening in the Swedish context |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Trial governance, Simvastatin as a neuroprotective treatment for Parkinson's Disease: a double-blind, randomised, placebo controlled futility study in patients of moderate severity (PD-STAT) |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Trial governance, TSC, HAND-1 feasibility study |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial governance, TSC/PSC, INFORM Programme (including qualitative and trial workstreams) |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial steering committee NEON trial - Will Hollingworth |
| Geographic Reach | National |
| Policy Influence Type | Participation in a advisory committee |
| Description | Trial steering committee Show RESPECT (RESults to Participants Engaged in Clinical Trials) - Talia Isaacs |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Trial steering committee WAX trial - Leila Rooshenas |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Trial steering committee: The ECASS Study: Evaluation of a Computer Aid for assessing Stomach Problems |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Visiting Professor of Medicine, Duke University, Durham, USA - Jenny Donovan |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Participation in a advisory committee |
| Description | Working Group to update MRC Complex Intervention Guidelines |
| Geographic Reach | Multiple continents/international |
| Policy Influence Type | Membership of a guideline committee |
| Description | "Qualitative Ancillary Study: Understanding and optimising recruitment to the TARVA trial TARVA: Total Ankle Replacement Versus Arthrodesis" |
| Amount | £14,515 (GBP) |
| Funding ID | HTA - 12/35/27 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2017 |
| End | 10/2017 |
| Description | A RCT to establish the clinical and cost effectiveness of expectant management versus pre-operative imaging with MRCP in patients with symptomatic gallstones undergoing laparoscopic cholecystectomy at low or moderate risk of common bile duct stones: |
| Amount | £2,857,515 (GBP) |
| Funding ID | HTA/16/142/04 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2018 |
| End | 05/2024 |
| Description | A Randomised Controlled Trial to investigate the clinical and cost-effectiveness of Paravertebral Blockade compared with Thoracic Epidural Blockade in reducing Chronic Post-Thoracotomy Pain (TOPIC 2) |
| Amount | £1,661,405 (GBP) |
| Funding ID | HTA/16/111/111 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2018 |
| End | 10/2022 |
| Description | A Randomised Trial of Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC) |
| Amount | £15,693 (GBP) |
| Funding ID | 19399 |
| Organisation | Cancer Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2016 |
| End | 09/2016 |
| Description | A clinical effectiveness investigation of a multi-faceted intervention (incorporating a prognostic algorithm) to improve management of antibiotics for CHIldren presenting to primary care with acute COugh and respiratory tract infection (CHICO): an effic |
| Amount | £826,831 (GBP) |
| Funding ID | 16/31/98 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | A feasibility study and pilot RCT to establish methods for assessing the acceptability, and clinical and cost-effectiveness of enhanced psychological care (EPC) in cardiac rehabilitation services for patients with new onset depression compared with treatm |
| Amount | £448,291 (GBP) |
| Funding ID | HTA - 12/189/06 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 07/2016 |
| Description | A multicentre cluster randomised controlled trial to evaluate the effectiveness and cost-effectiveness of a school-based peer-led drug prevention intervention (The FRANK friends study) |
| Amount | £1,465,055 (GBP) |
| Funding ID | PHR/17/97/02 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2019 |
| End | 06/2022 |
| Description | A multicentre double-blind placebo-controlled randomised trial of SerTRaline for AnxieTy in adults with Autism (STRATA) |
| Amount | £1,669,263 (GBP) |
| Funding ID | NIHR127337 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2019 |
| End | 09/2023 |
| Description | A multicentre randomised controlled trial of splint duration for mallet injuries (MALIT) |
| Amount | £11,570 (GBP) |
| Organisation | British Association of Plastic Reconstructive and Aesthetic Surgeons |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2015 |
| End | 05/2016 |
| Description | A network meta-analysis of complex interventions to prevent mental-ill-health in children and young people: evaluation of effective and cost-effective intervention components |
| Amount | £350,079 (GBP) |
| Funding ID | 15/49/08 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2016 |
| End | 06/2018 |
| Description | A phase 3 trial of Rivastigmine to prevent falls in Parkinson's Disease |
| Amount | £2,545,636 (GBP) |
| Funding ID | HTA/16/31/13 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2017 |
| End | 12/2021 |
| Description | A pragmatic multicentre randomised controlled trial to assess the clinical and cost effectiveness of negative pressure wound therapy versus usual care for surgical wounds healing by secondary intention (SWHSI 2) |
| Amount | £1,631,171 (GBP) |
| Funding ID | HTA/17/42/94 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2018 |
| End | 10/2022 |
| Description | A prospective multicentre cohort study to inform the feasibility and conduct of a pragmatic randomised clinical trial comparing new techniques of implant based breast reconstruction (iBRA study) |
| Amount | £221,363 (GBP) |
| Funding ID | PB-PG-0214-33065 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2015 |
| End | 12/2017 |
| Description | A prospective multicentre cohort study to inform the feasibility and conduct of a pragmatic randomised clinical trial comparing new techniques of implant based breast reconstruction (iBRA study) |
| Amount | £221,363 (GBP) |
| Funding ID | PB-PG-0214-33065 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2015 |
| End | 12/2017 |
| Description | A randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of laparoscopic cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated sy |
| Amount | £1,397,962 (GBP) |
| Funding ID | HTA/14/192/71 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 04/2021 |
| Description | A randomised controlled trial of Partial prostate Ablation versus Radical prosTatectomy (PART) in intermediate risk unilateral clinically localised prostate cancer a feasibility study |
| Amount | £655,011 (GBP) |
| Funding ID | HTA 12/35/54 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2015 |
| End | 01/2017 |
| Description | A randomised controlled trial of Partial prostate Ablation versus Radical prosTatectomy (PART) in intermediate risk, unilateral clinically localised prostate ca |
| Amount | £3,618,248 (GBP) |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | A randomised controlled trial on the effectiveness of GP promotion of e-cigarettes in supporting reduced smoking and abstinence in hardcore smokers with smoking-related chronic disease (ERASE). |
| Amount | £308,980 (GBP) |
| Funding ID | 333 |
| Organisation | Scottish School of Primary Care |
| Department | Scottish Primary Care Research Network (SPCRN) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2016 |
| End | 09/2018 |
| Description | A randomised controlled trial on the effectiveness of GP promotion of e-cigarettes in supporting reduced smoking and abstinence in hardcore smokers with smoking-related chronic disease (ERASE). |
| Amount | £308,980 (GBP) |
| Funding ID | PDF-2016-09-043 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2016 |
| End | 09/2018 |
| Description | A randomised controlled trial to establish the clinical and cost effectiveness of expectant management versus pre-operative imaging with MRCP in patients with symptomatic gallstones undergoing laparoscopic cholecystectomy at low or moderate risk of common |
| Amount | £2,900,000 (GBP) |
| Funding ID | 16/142/04 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2018 |
| End | 05/2024 |
| Description | A systematic review of the assessment of implementation fidelity in primary care trials |
| Amount | £50,546 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 02/2017 |
| Description | A woman-centred, tailored SMS-delivered multi-component intervention for weight loss and maintenance of weight loss in the postpartum period: intervention adaptation and pilot RCT |
| Amount | £483,040 (GBP) |
| Funding ID | PHR/14/67/20 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2016 |
| End | 08/2018 |
| Description | ACTION 330: A cluster randomised feasibility trial evaluation of a teaching assistant led, extracurricular physical activity intervention for 8 to 10 year olds. |
| Amount | £507,782 (GBP) |
| Funding ID | 15/55/09 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 09/2017 |
| Description | Academy of Medical Sciences Starter grants for clinical lecturers |
| Amount | £20,336 (GBP) |
| Organisation | Academy of Medical Sciences (AMS) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2014 |
| End | 10/2016 |
| Description | Acceptability of randomisation to RCTs in adults with autism (APRiCOT study). |
| Amount | £29,683 (GBP) |
| Organisation | Avon and Wiltshire Mental Health Partnership NHS Trust |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2019 |
| End | 04/2020 |
| Description | Adaptation of evidence-informed complex population health interventions for implementation and/or re-evaluation in new contexts: New guidance |
| Amount | £320,261 (GBP) |
| Funding ID | MR/R013357/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2018 |
| End | 08/2020 |
| Description | Advancing the integration of mixed methods in clinical trials: a two day summit |
| Amount | £9,950 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Hubs for Trial Methodology Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 12/2016 |
| End | 07/2017 |
| Description | Antidepressants to prevent relapse in depression |
| Amount | £1,668,027 (GBP) |
| Funding ID | HTA/13/115/48 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2015 |
| End | 09/2019 |
| Description | Antidepressants to prevent relapse in depression |
| Amount | £1,668,027 (GBP) |
| Funding ID | HTA/13/115/48 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Antidepressants to prevent relapse in depression. |
| Amount | £1,668,027 (GBP) |
| Funding ID | HTA - 13/115/148 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Aspirin for Venous Ulcers: Randomised Trial (AVURT) |
| Amount | £500,000 (GBP) |
| Funding ID | 13/87/08 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2014 |
| Description | Assets-based feeding help Before and After birth (ABA): feasibility study for improving breastfeeding initiation and continuation. |
| Amount | £328,980 (GBP) |
| Funding ID | 15/53/04 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2016 |
| End | 10/2018 |
| Description | BASIL-2: Bypass vs. Angioplasty in Severe Ischaemia of the Leg-2 |
| Amount | £2,000,000 (GBP) |
| Funding ID | HTA 12/35/45 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2014 |
| Description | Basil-3: BAlloon vs Stenting in Severe Ischaemia of the Leg-3 |
| Amount | £2,000,000 (GBP) |
| Funding ID | 13/81/02 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2015 |
| Description | Biomedical Research Centre |
| Amount | £4,500,000 (GBP) |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 03/2022 |
| Description | Bristol Biomedical Research Centre - Surgical Innovation Theme |
| Amount | £2,020,517 (GBP) |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 03/2022 |
| Description | Bristol Surgical Trials Centre |
| Amount | £500,000 (GBP) |
| Organisation | Royal College of Surgeons of England |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | British Academy Visiting Fellowship - Katrina Hutchison |
| Amount | £6,834 (GBP) |
| Organisation | The British Academy |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | |
| Description | CITED RCT of a community intervention for late life depression in Brazil (Araya) |
| Amount | £11,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2014 |
| End | 06/2015 |
| Description | CONservative TReatment of Appendicitis in Children a randomised controlled Trial CONTRACT (Feasibility study) |
| Amount | £482,882 (GBP) |
| Funding ID | HTA - 14/192/90 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2016 |
| End | 05/2019 |
| Description | CONservative TReatment of Appendicitis in Children a randomised controlled Trial CONTRACT (Feasibility study) |
| Amount | £444,985 (GBP) |
| Funding ID | HTA - 14/192 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Calibration of absolute and relative treatment effects using individual patient data: Matching-adjusted Indirect Comparisons (MAIC) and Simulated Treatment Comparisons (STC) in Technology Appraisals. |
| Amount | £18,000 (GBP) |
| Funding ID | 214133 |
| Organisation | National Institute for Health and Care Excellence (NICE) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 08/2016 |
| Description | Calibration of multiple treatment comparisons using individual patient data. MRC Methodology Research Panel. |
| Amount | £308,461 (GBP) |
| Funding ID | MR/P015298/2 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2017 |
| End | 12/2019 |
| Description | Calibration of multiple treatment comparisons using individual patient data. MRC Methodology Research Panel. |
| Amount | £308,461 (GBP) |
| Funding ID | MR/P015298/2 |
| Organisation | Medical Research Council (MRC) |
| Department | MRC/NIHR Methodology Research Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2017 |
| End | 12/2019 |
| Description | Cessation in Pregnancy Incentives Trial: A multi-centre phase III randomised controlled trial. |
| Amount | £1,413,973 (GBP) |
| Funding ID | 20863 |
| Organisation | Cancer Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2017 |
| End | 08/2020 |
| Description | Children's drops for ear pain in acute otitis media: the CEDAR randomised controlled trial |
| Amount | £1,377,900 (GBP) |
| Funding ID | HTA/13/88/13 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2015 |
| End | 12/2015 |
| Description | Choice of moisturiser for eczema (COMET). |
| Amount | £435,403 (GBP) |
| Funding ID | PB-PG-0712-28056 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2013 |
| End | 06/2015 |
| Description | Chronic pain after total knee replacement: better post-operative prevention and management (the STAR Programme) |
| Amount | £100,937 (GBP) |
| Funding ID | RP-DG-1211-10002 |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2015 |
| End | 09/2020 |
| Description | Cluster randomised controlled trial (RCT) for late life depression in socioeconomically deprived areas of São Paulo, Brazil (PROACTIVE) |
| Amount | £522,570 (GBP) |
| Funding ID | MR/R006229/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2018 |
| End | 06/2021 |
| Description | Cluster randomised controlled trial (RCT) for late life depression in socioeconomically deprived areas of Sao Paulo, Brazil (PROACTIVE). |
| Amount | £1,104,894 (GBP) |
| Funding ID | MR/R006229/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Core Outcomes for Burn Care Research: short-term outcomes and outcome measures for use in burn care efficacy trials. MRC/Wellcome Trust Joint Global Health Trials Initiative and FAPESP |
| Amount | £140,000 (GBP) |
| Organisation | Scar Free Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2018 |
| End | 10/2021 |
| Description | DRIFT - follow up (Luyt) |
| Amount | £300,000 (GBP) |
| Funding ID | HTA/12/35/61 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2014 |
| End | 05/2016 |
| Description | Developing a medical work force to design and conduct trials to improve evidence-based practice: a case study of surgical Trainee Research Collaboratives and a stakeholder workshop (ReSurgEnT) |
| Amount | £49,969 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Human Nutrition Research Group |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 12/2016 |
| End | 12/2017 |
| Description | Developing a new composite outcome measure for cardiac surgery trials |
| Amount | £53,178 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 09/2018 |
| Description | Developing, delivering and evaluating training courses for recruiters to randomised trials |
| Amount | £36,962 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 08/2015 |
| Description | Development of a SPIRIT-PRO Extension: Delphi survey consensus meeting and publication |
| Amount | £55,000 (GBP) |
| Organisation | Macmillan Cancer Support |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2016 |
| End | 12/2017 |
| Description | Development of a central resource for research in recruitment in clinical trials (ORCCA database) |
| Amount | £90,261 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 08/2016 |
| Description | Development of a multilevel and mixture-model framework for modelling epigenetic changes over time |
| Amount | £296,416 (GBP) |
| Funding ID | MR/M025020/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2016 |
| End | 07/2018 |
| Description | ETTAA QRI |
| Amount | £11,036 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Hubs for Trial Methodology Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2017 |
| End | 10/2020 |
| Description | Effectiveness, cost efectiveness and safety of gabapentin versus placebo as an adjunct to multimodal pain regimens in surgical patients: A placebo controlled randomised controlled trial with blinding (The GAP study) |
| Amount | £1,139,565 (GBP) |
| Funding ID | HTA - 15/101/16 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Efficient sample schemes for estimation of value of information of future research. MRC Network of Hubs for Trials Methodology Research. |
| Amount | £34,756 (GBP) |
| Funding ID | N79 |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2021 |
| Description | Evaluating QuinteT Recruitment Training workshops |
| Amount | £2,189 (GBP) |
| Organisation | University of York |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2019 |
| End | 12/2019 |
| Description | Evaluating new models of care for people with long term conditions (Salisbury) |
| Amount | £1,769,619 (GBP) |
| Organisation | National Institute for Health Research |
| Department | Health Services and Delivery Research (HS&DR) Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 05/2017 |
| Description | Examining the influence of an informational video on participant retention in a randomised controlled trial. |
| Amount | £9,051 (GBP) |
| Organisation | Irish Health Research Board |
| Sector | Charity/Non Profit |
| Country | Ireland |
| Start | 05/2017 |
| End | 05/2018 |
| Description | Exploring patient perspectives of recruitment in randomised controlled trials |
| Amount | £117,882 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Hubs for Trial Methodology Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2017 |
| End | 10/2020 |
| Description | Exploring strategies for implementing core information sets for informed consent to surgery for head and neck cancer: operationalising Montgomery |
| Amount | £30,000 (GBP) |
| Funding ID | SGL018\1002 |
| Organisation | Academy of Medical Sciences (AMS) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 03/2020 |
| Description | Extending ORRCA to create a central resource for retention research within clinical trials (ORRCA 2) |
| Amount | £40,830 (GBP) |
| Funding ID | N101 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2018 |
| End | 12/2018 |
| Description | Fatigue - Reducing its Effects through individualised support Episodes in Inflammatory Arthritis (FREE-IA): A Feasibility Study for a Randomised Controlled Trial |
| Amount | £248,079 (GBP) |
| Funding ID | PB-PG-1216-20014 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2018 |
| End | 05/2020 |
| Description | Fatigue - Reducing its Effects through individualised support Episodes in Inflammatory Arthritis (FREE-IA): A Feasibility Study for a Randomised Controlled Trial |
| Amount | £248,039 (GBP) |
| Funding ID | PB-PG-1216-20014 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 03/2020 |
| Description | Feasibility study of how best to engage obese men in narrative SMS (short message system) and incentive interventions for weight loss, to inform a future effectiveness and cost-effectiveness trial |
| Amount | £490,970 (GBP) |
| Funding ID | PHR/14/185/09 |
| Organisation | National Institute for Health Research |
| Department | Public Health Research (PHR) Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2016 |
| End | 08/2018 |
| Description | Full Randomised Controlled Trial of Arthroscopic Surgery for Hip Impingement versus best Conventional care UK FASHIoN 2 |
| Amount | £1,727,557 (GBP) |
| Funding ID | HTA - 13/103/02 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 02/2020 |
| Description | Gastric Bypass, adjustable gastric Banding or Sleeve gastrectomy surgery to treat severe and complex obesity: a multi-centre randomised controlled trial |
| Amount | £3,939,934 (GBP) |
| Funding ID | HTA - 09/127/53 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2015 |
| End | 07/2018 |
| Description | Guidance to optimise pilot study design and conduct: HTMR and NIHR HTA 'Research on Research' proposal |
| Amount | £13,280 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 11/2016 |
| End | 09/2017 |
| Description | Guidance to optimise pilot study design and conduct: A joint HTMR and NIHR HTA 'Research on Research' proposal |
| Amount | £30,596 (GBP) |
| Funding ID | N85 |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 09/2016 |
| End | 08/2017 |
| Description | Guided self-help for depression in adults with autism spectrum disorder |
| Amount | £355,155 (GBP) |
| Funding ID | HTA/14/43/02 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 03/2018 |
| Description | Guided self-help for depression in adults with autism spectrum disorder (ADEPT) |
| Amount | £418,442 (GBP) |
| Funding ID | HTA - 14/43/02 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 12/2015 |
| End | 12/2018 |
| Description | H4RT: The High-volume Haemodiafiltration vs High-flux Haemodialysis Registry Trial. |
| Amount | £747,882 (GBP) |
| Funding ID | 15/80/52 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | HOD1: Inferring relative treatment effects from combined randomised and observational data |
| Amount | £737,952 (GBP) |
| Funding ID | MR/R025223/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2019 |
| End | 12/2021 |
| Description | HOD: Assessing risk of bias in non-randomized studies of interventions |
| Amount | £635,652 (GBP) |
| Funding ID | MR/M025209/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2015 |
| End | 02/2018 |
| Description | Health Economics Analysis Plans: developing content guidance through consensus |
| Amount | £39,697 (GBP) |
| Funding ID | N91 |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Hubs for Trial Methodology Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 03/2018 |
| Description | Health Economics Analysis Plans: developing content guidance through consensus. |
| Amount | £39,697 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 03/2018 |
| Description | Heath Technology Assessment |
| Amount | £999,978 (GBP) |
| Funding ID | HTA/14/192/109 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 10/2021 |
| Description | How do smoking cessation medicines compare with respect to their neuropsychiatric safety: a systematic review, network meta-analysis and cost effectiveness analysis |
| Amount | £261,107 (GBP) |
| Funding ID | 5/58/18 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2016 |
| End | 08/2018 |
| Description | Identification of iems for inclusion in a standardised resource-use measure |
| Amount | £19,612 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 02/2015 |
| End | 01/2016 |
| Description | Identification of items for inclusion in a standardised resource-use measure (Thorn) |
| Amount | £19,612 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Hubs for Trial Methodology Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2015 |
| End | 01/2016 |
| Description | Identifying and critiquing different approaches to developing complex interventions (INDEX study) |
| Amount | £380,033 (GBP) |
| Funding ID | MR/N015339/1 |
| Organisation | Medical Research Council (MRC) |
| Department | MRC/NIHR Methodology Research Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2016 |
| End | 03/2018 |
| Description | Identifying and critiquing different approaches to developing complex interventions (INDEX study). |
| Amount | £380,463 (GBP) |
| Funding ID | MR/N015339/1 |
| Organisation | Medical Research Council (MRC) |
| Department | MRC/NIHR Methodology Research Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2018 |
| Description | Identifying research directions in palliative surgery in oncology |
| Amount | £1,625 (GBP) |
| Organisation | University of Bristol |
| Department | Elizabeth Blackwell Institute for Health Research |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | |
| Description | Impact Award - Refinement of and extension to the Cochrane Risk of Bias tool for Randomised trials |
| Amount | £9,977 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2018 |
| End | 10/2019 |
| Description | Impact of health on social and economic outcome: qualitative study. |
| Amount | £449,973 (GBP) |
| Organisation | Health Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 03/2021 |
| Description | Improving the design of RCT's in surgery: understanding how to describe and standardise co-interventions |
| Amount | £26,250 (GBP) |
| Funding ID | SGL013\1005 |
| Organisation | Academy of Medical Sciences (AMS) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2015 |
| End | 08/2017 |
| Description | Improving the management of patients with multimorbidity in general practice |
| Amount | £1,789,589 (GBP) |
| Funding ID | 12/130/15 |
| Organisation | National Institute for Health Research |
| Department | Health Services and Delivery Research (HS&DR) Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 09/2017 |
| Description | Incorporating external evidence syntheses in the analysis of a clinical trial |
| Amount | £71,628 (GBP) |
| Funding ID | HTMR Q10 |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Hubs for Trial Methodology Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 03/2018 |
| Description | Inform: Infection after total joint replacement |
| Amount | £2,012,256 (GBP) |
| Funding ID | RP-PG-1210-12005 |
| Organisation | National Institute for Health Research |
| Department | Programme Grants for Applied Research (PGfAR) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Inform: Infection after total joint replacement. |
| Amount | £825,000 (GBP) |
| Funding ID | RP-PG-1210-12005 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Integrated therapist and online CBT for depression in primary care |
| Amount | £2,233,801 (GBP) |
| Funding ID | RP-PG-0514-20012 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 04/2022 |
| Description | Integrated therapist and online CBT for depression in primary care |
| Amount | £2,233,801 (GBP) |
| Funding ID | RP-PG-0514-20012 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2022 |
| Description | Integrated therapist and online CBT for depression in primary care (INTERACT) |
| Amount | £2,233,800 (GBP) |
| Funding ID | RK7725 |
| Organisation | National Institute for Health Research |
| Department | Programme Grants for Applied Research (PGfAR) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Integrated therapist and online CBT for depression in primary care. (INTERACT) |
| Amount | £2,233,801 (GBP) |
| Funding ID | RP-PG-0514-20012. |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2022 |
| Description | Investigating the effectiveness and cost effectiveness of using FITNET to treat paediatric CFS/ME in the UK |
| Amount | £999,977 (GBP) |
| Funding ID | HTA 14/192/109 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 10/2021 |
| Description | Investigating the treatment of paediatric chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) |
| Amount | £864,736 (GBP) |
| Funding ID | SRF-2013-06-013 |
| Organisation | National Institute for Health Research |
| Department | NIHR Fellowship Programme |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2014 |
| End | 10/2019 |
| Description | Investigating the treatment of paediatric chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) (MAGENTA RCT) |
| Amount | £864,736 (GBP) |
| Funding ID | SRF-2013-06-013 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2014 |
| End | 01/2019 |
| Description | Long term follow up of patients in the COBALT (CBT for treatment resistant depression) trial |
| Amount | £162,230 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2013 |
| End | 08/2014 |
| Description | Losing the losses: understanding the reasons for attrition in RCTs and developing the evidence to prevent it |
| Amount | £216,000 (GBP) |
| Funding ID | MR/K024310/1 |
| Organisation | Medical Research Council (MRC) |
| Department | MRC/NIHR Methodology Research Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2015 |
| End | 12/2016 |
| Description | Low intensity interventions for antenatal depression: A feasibility study of an RCT of Interpersonal Counselling compared to Cognitive Behavioural Therapy. |
| Amount | £245,672 (GBP) |
| Funding ID | PB-PG-1216-20027 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2018 |
| End | 05/2020 |
| Description | Low intensity interventions for antenatal depression: A feasibility study of an RCT of Interpersonal Counselling compared to Cognitive Behavioural Therapy. |
| Amount | £241,934 (GBP) |
| Funding ID | PB-PG-1216-20027 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 12/2019 |
| Description | MALIT: A multicentre randomised controlled trial of splint duration for mallet injuries |
| Amount | £23,140 (GBP) |
| Organisation | British Society for Surgery of the Hand (BSSH) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2015 |
| End | 04/2016 |
| Description | MALIT: A multicentre randomised controlled trial of splint duration for mallet injuries. |
| Amount | £23,140 (GBP) |
| Organisation | British Society for Surgery of the Hand (BSSH) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2015 |
| End | 04/2016 |
| Description | MASTER |
| Amount | £20,099 (GBP) |
| Funding ID | HTA/11/106/01 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 11/2016 |
| Description | MASTER |
| Amount | £20,099 (GBP) |
| Funding ID | HTA/11/106/01 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 01/2016 |
| Description | MICA: Model Based Network Meta-Analysis for Pharmacometrics and Drug-Development. |
| Amount | £201,060 (GBP) |
| Funding ID | MR/M005615/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | MRC HTMR - Advancing training for health professionals and trialists to optimise RCT recruitment and informed consent |
| Amount | £10,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2018 |
| End | 06/2019 |
| Description | MRC HTMR - IMPACT: Identification of items for inclusion in a standardised resource-use measure |
| Amount | £4,286 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 12/2018 |
| End | 11/2019 |
| Description | MRC HTMR- MPACT: Health Economics Analysis Plans: developing content guidance through consensus |
| Amount | £6,840 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2018 |
| End | 05/2019 |
| Description | MRC HTMR: Improving the evaluation of medical devices with development of a generic core outcome set: a key stakeholder workshop for industry, innovators, clinicians, trialists, journal editors and health policy makers |
| Amount | £9,938 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2018 |
| End | 06/2019 |
| Description | MRC Network of Hubs for Trials Methodology Research |
| Amount | £47,175 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 10/2018 |
| Description | MRC Network of Hubs for Trials Methodology Research:PhD studentships |
| Amount | £92,088 (GBP) |
| Funding ID | P5-2014-LB |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2014 |
| End | 09/2018 |
| Description | MRC PhD studentship |
| Amount | £53,178 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 09/2018 |
| Description | MRC-NIHR MRP: Inferring relative treatment effects from combined randomised and observational data. |
| Amount | £725,176 (GBP) |
| Funding ID | MR/R025223/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2019 |
| Description | Mesothelioma and Radical Surgery 2: a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decortication for patients with malignant pleural mesothelioma (MARS 2) |
| Amount | £1,725,924 (GBP) |
| Funding ID | 15/188/31 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2017 |
| Description | Meta-Modelling for Value of Information Calculations Workshop. |
| Amount | £9,160 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | |
| Description | Model Based Network Meta-Analysis for Pharmacometrics and Drug-Development |
| Amount | £327,555 (GBP) |
| Funding ID | MR/M005615/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 12/2017 |
| Description | Monitoring for neovascular AMD Reactivation at Home: the MONARCH study |
| Amount | £1,139,565 (GBP) |
| Funding ID | HTA/15/97/02 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Multi-centre randomised controlled trial to compare the clinical and cost-effectiveness of a 'vein bypass first' with a 'best endovascular treatment first' revascularisation strategy for severe limb ischaemia due to infra-popliteal arterial disease (BASIL |
| Amount | £11,573 (GBP) |
| Funding ID | HTA/12/35/45 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2016 |
| End | 01/2017 |
| Description | Multidisciplinary Workshop on shared decision-making in birth mode planning |
| Amount | £10,000 (GBP) |
| Organisation | University of Aberdeen |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2019 |
| End | 11/2019 |
| Description | NAP SACC UK: A feasibility cluster randomised controlled trial in child care settings to increase physical activity and healthy eating in 2-4 year olds |
| Amount | £431,495 (GBP) |
| Funding ID | PHR/12/153/39 |
| Organisation | National Institute for Health Research |
| Department | Public Health Research (PHR) Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2014 |
| End | 11/2017 |
| Description | NICE Clinical Guidelines Technical Support Unit |
| Amount | £327,489 (GBP) |
| Organisation | National Institute for Health and Care Excellence (NICE) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2019 |
| Description | NICE Clinical Guidelines Technical Support Unit. |
| Amount | £350,000 (GBP) |
| Organisation | National Institute for Health and Care Excellence (NICE) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2022 |
| Description | NICE Clinical Guidelines Technical Support Unit. |
| Amount | £350,000 (GBP) |
| Organisation | National Institute for Health and Care Excellence (NICE) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2018 |
| Description | NIHR HS&DR: Improving medicines use in people with polypharmacy in primary care (IMPPP) |
| Amount | £1,872,267 (GBP) |
| Funding ID | HS&DR/16/118/14 |
| Organisation | National Institute for Health Research |
| Department | Health Services and Delivery Research (HS&DR) Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | NIHR HTA |
| Amount | £655,011 (GBP) |
| Funding ID | HTA 12/35/54 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2015 |
| End | 01/2017 |
| Description | NIHR HTA |
| Amount | £2,119,632 (GBP) |
| Funding ID | HTA - 14/140/78 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 12/2015 |
| End | 12/2021 |
| Description | NIHR HTA Programme |
| Amount | £448,921 (GBP) |
| Funding ID | HTA - 12/189/06 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 02/2017 |
| Description | NIHR HTA Programme |
| Amount | £1,642,978 (GBP) |
| Funding ID | HTA - 13/04/03 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2015 |
| End | 04/2021 |
| Description | NIHR HTA [UK RTC Arthroscopic Surgery...] |
| Amount | £1,727,577 (GBP) |
| Funding ID | HTA - 13/103/02 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 02/2020 |
| Description | NIHR Infrastructure Short Placement Award for Research Collaboration (SPARC). Developing advanced evidence synthesis skills to inform rapid and focused surgical innovation: a training placement between the Bristol BRC (Surgical Innovation theme) and the M |
| Amount | £2,842 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 03/2019 |
| Description | NIHR PHR [Travel to Work] |
| Amount | £972,682 (GBP) |
| Organisation | National Institute for Health Research |
| Department | Public Health Research (PHR) Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2014 |
| End | 03/2017 |
| Description | NIHR Programme Grant for Applied Research |
| Amount | £2,233,801 (GBP) |
| Funding ID | RP-PG-0514-20012 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2022 |
| Description | NIHR Research Design Service South West (RDS SW) Infrastructure grant |
| Amount | £1,806,883 (GBP) |
| Organisation | Infrastructure UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2018 |
| End | 09/2023 |
| Description | NIHR Research for Patient Benefit |
| Amount | £250,000 (GBP) |
| Funding ID | RfPB 0214-33065 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2015 |
| End | 05/2018 |
| Description | NIHR RfPB - Does Laryngeal Reinnervation or Type I Thyroplasty give better voice results for patients with Unilateral Vocal Fold Paralysis (VOCALIST): a feasibility study |
| Amount | £309,667 (GBP) |
| Funding ID | PB-PG-1013-32058 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2015 |
| End | 08/2016 |
| Description | NIHR RfPB Competition 22 |
| Amount | £259,754 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2015 |
| End | 04/2017 |
| Description | NIHR RfPB Competition 22 [Testing the feasibility of a consultation-level intervention for frequent attenders with clinically inexplicable symptoms in primary care. ] |
| Amount | £249,940 (GBP) |
| Funding ID | PB-PG-0613-31099 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2014 |
| End | 05/2017 |
| Description | NIHR SPCR- Identifying the Quality Indicators of a Patient-Centred Trial: obtaining expert consensus using the Delphi method |
| Amount | £11,208 (GBP) |
| Organisation | Scottish School of Primary Care |
| Department | Scottish Primary Care Research Network (SPCRN) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2015 |
| End | 09/2015 |
| Description | NIHR School for Primary Care Research: Long-term condition management |
| Amount | £79,542 (GBP) |
| Funding ID | 207 |
| Organisation | National Institute for Health Research |
| Department | School for Primary Care Research |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 06/2015 |
| Description | NIHR School for primary care research: The TEST (Trial of Eczema allergy Screening Tests) Study: feasibility randomised controlled trial with economic scoping and nested qualitative study |
| Amount | £438,692 (GBP) |
| Organisation | National Institute for Health Research |
| Department | School for Primary Care Research |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | |
| Description | NIHR Senior Investigator Award |
| Amount | £63,210 (GBP) |
| Organisation | National Institute for Health Research |
| Department | NIHR Fellowship Programme |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | NIHR-Research for Patient Benefit [Needle fasciotomy v limited fasciectomy...] |
| Amount | £259,754 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2015 |
| End | 04/2017 |
| Description | Nasal Airway Obstruction Study (Nairos) |
| Amount | £5,655 (GBP) |
| Funding ID | HTA/14/226/07 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Needle fasciotomy versus limited fasciectomy for the treatment of Dupuytren's contractures of the fingers: a study which investigates the feasibility, acceptability and design of a multicentre randomised trial |
| Amount | £259,754 (GBP) |
| Funding ID | PB-PG-0613-31083 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2015 |
| End | 04/2017 |
| Description | Needle fasciotomy versus limited fasciectomy for treatment of Dupuytren's contractures of fingers: a randomised non-inferiority trial with an individual participant data network meta-analysis (HAND-2). |
| Amount | £1,280,920 (GBP) |
| Funding ID | NIHR127393 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 12/2024 |
| Description | OSAC (Oral Steroids for Acute Cough) Trial. |
| Amount | £1,506,076 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2012 |
| End | 06/2015 |
| Description | Optimal Personalised Treatment of early breast cancer usIng Multi-parameter Analysis |
| Amount | £3,373,808 (GBP) |
| Funding ID | HTA - 10/34/501 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 04/2024 |
| Description | Optimisation, feasibility testing and pilot randomised trial of Positive Choices: a school based social marketing intervention to promote sexual health, prevent unintended teenage pregnancies and address health inequalities in England |
| Amount | £595,368 (GBP) |
| Funding ID | PHR/14/184/02 |
| Organisation | National Institute for Health Research |
| Department | Public Health Research (PHR) Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 07/2020 |
| Description | Optimising management of fistulating perianal Crohn's disease |
| Amount | £56,589 (GBP) |
| Organisation | Bowel Disease Research Foundation (BDRF) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2017 |
| End | 05/2020 |
| Description | PET-CT guided, symptom-based, patient-driven surveillance versus clinical follow-up in advanced head neck cancer (PET NECK 2) |
| Amount | £3,000,000 (GBP) |
| Organisation | National Institute for Health Research |
| Department | Programme Grants for Applied Research (PGfAR) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 12/2024 |
| Description | PRECISE: A health economic approach to evaluate uncertain evidence in personalised medicine |
| Amount | £23,378 (GBP) |
| Organisation | NordForsk |
| Sector | Charity/Non Profit |
| Country | Norway |
| Start | 05/2019 |
| End | 05/2023 |
| Description | Patient-centred trials: developing measures to improve the experience of people taking part in clinical trials |
| Amount | £7,898 (GBP) |
| Funding ID | PB-PG-0416-20033 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2017 |
| End | 02/2019 |
| Description | Personal launching fellowship to disseminate work from PhD and apply for future funding |
| Amount | £47,104 (GBP) |
| Organisation | Avon Primary Care Research Collaborative |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 10/2018 |
| Description | PhD Scholarship |
| Amount | £13,863 (GBP) |
| Organisation | University of Bristol |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 11/2014 |
| End | 06/2022 |
| Description | Phase I-II of the update of the EORTC Quality of Life Gastric module QLQ-STO22 |
| Amount | € 85,771 (EUR) |
| Organisation | EORTC |
| Sector | Charity/Non Profit |
| Country | Belgium |
| Start | |
| Description | Phase III randomised controlled trial Comparing Alternative Regimens for escalating treatment of intermediate and high-risk oropharyngeal cancer (Compare). |
| Amount | £170,697,200 (GBP) |
| Funding ID | CRUK/13/026 |
| Organisation | Cancer Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 11/2014 |
| End | 11/2022 |
| Description | Pilot randomised trial of Project Respect: a school-based intervention to prevent dating and relationship violence and address health inequalities among young people |
| Amount | £483,065 (GBP) |
| Funding ID | NIHR PHR 15/03/09 |
| Organisation | National Institute for Health Research |
| Department | Public Health Research (PHR) Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 12/2018 |
| Description | Pragmatic, primary care, multi -centre, individually randomised superiority trial of four emollients in children with eczema, with internal pilot, nested economic evaluation and qualitative study |
| Amount | £1,394,969 (GBP) |
| Funding ID | 15/130/06 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Preventing gambling related harm in adolescents: developing a peer-led, social network intervention |
| Amount | £151,622 (GBP) |
| Funding ID | MR/S019200/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2019 |
| End | 01/2021 |
| Description | Primary care patients' views and experiences of treatments for depression: a secondary analysis of qualitative data |
| Amount | £79,543 (GBP) |
| Funding ID | 207 |
| Organisation | National Institute for Health Research |
| Department | School for Primary Care Research |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 06/2015 |
| Description | Primary care patients' views and experiences of treatments for depression: a secondary analysis of qualitative data. |
| Amount | £79,542 (GBP) |
| Funding ID | 207 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 06/2015 |
| Description | Prioritising research for an entire clinical area (Eczema) using value of information (VoI) methods |
| Amount | £1,789,589 (GBP) |
| Funding ID | CDF-2014-07-006 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 09/2017 |
| Description | Production of Technology Assessment Reviews (TARs) for the NIHR (Stewart) |
| Amount | £5,249,998 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 03/2021 |
| Description | ProgrammE in Costing, resource use measurement and outcome valuation for Use in multi-sectoral National and International health economic evaluAtions (PECUNIA) |
| Amount | £65,330 (GBP) |
| Funding ID | 779292 |
| Organisation | European Commission H2020 |
| Sector | Public |
| Country | Belgium |
| Start | 01/2018 |
| End | 12/2020 |
| Description | RCS The PreBRA Study |
| Amount | £61,470 (GBP) |
| Organisation | Royal College of Surgeons of England |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2018 |
| End | 10/2019 |
| Description | REPROVIDE (Reaching Everyone Programme of Research On Violence in diverse Domestic Environments). |
| Amount | £2,529,230 (GBP) |
| Funding ID | RP-PG-0614-20011 |
| Organisation | National Institute for Health Research |
| Department | Programme Grants for Applied Research (PGfAR) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2016 |
| End | 02/2022 |
| Description | ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open): Definitive Trial. |
| Amount | £2,119,632 (GBP) |
| Funding ID | HTA/14/140/78 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 12/2015 |
| End | 05/2021 |
| Description | Randomised Oesophagectomy: Minimally Invasive or Open: Definitive trial (ROMIO) |
| Amount | £2,119,632 (GBP) |
| Funding ID | HTA - 14/140/78 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 12/2015 |
| End | 12/2021 |
| Description | Randomized trials of non-specific effects of childhood vaccines. |
| Amount | £6,095 (GBP) |
| Organisation | World Health Organization (WHO) |
| Sector | Public |
| Country | Global |
| Start | 04/2017 |
| End | 05/2017 |
| Description | Real-world treatment effectiveness in people with type 2 diabetes: Maximising the applicability of clinical trials |
| Amount | £456,470 (GBP) |
| Funding ID | MR/T017112/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2020 |
| End | 02/2023 |
| Description | Refinement of and extension to the Cochrane Risk of Bias tool for Randomised trials. |
| Amount | £50,000 (GBP) |
| Funding ID | MR/L004933/1- N61 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2015 |
| End | 10/2016 |
| Description | Routinely embedding recruitment and retention interventions within randomised controlled trials |
| Amount | £501,765 (GBP) |
| Funding ID | MR/R013748/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 09/2020 |
| Description | Royal College of Surgeons of England Research Fellowship |
| Amount | £55,000 (GBP) |
| Organisation | Royal College of Surgeons of England |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 10/2016 |
| Description | SMALL: A Phase III randomised multi-centre trial addressing overtreatment of small screen-detected breast cancer by comparing standard surgery with minimally invasive vacuum-assisted excision |
| Amount | £2,319,114 (GBP) |
| Funding ID | HTA/17/42/32 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2018 |
| End | 06/2029 |
| Description | Screening Strategies for Atrial Fibrillation: A Systematic Review and Cost-Effectiveness Analysis. |
| Amount | £181,379 (GBP) |
| Funding ID | HTA/14/141/01 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Smoking in FE colleges (Fletcher) |
| Amount | £72,400 (GBP) |
| Organisation | National Institute for Health Research |
| Department | Public Health Research (PHR) Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2014 |
| End | 06/2016 |
| Description | Starter Grants for Clinical Lecturers |
| Amount | £26,250 (GBP) |
| Organisation | Academy of Medical Sciences (AMS) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2015 |
| End | 08/2017 |
| Description | State-of-the-art workshop: Methods for placebo comparator group selection and use in surgical trials |
| Amount | £49,471 (GBP) |
| Funding ID | MC_PC_17155 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2018 |
| End | 06/2019 |
| Description | Studies to inform clinical aortic aneurysm research (including the development of an aortic aneurysm patient focus group and pilot stuies in emergency surgery |
| Amount | £176,000 (GBP) |
| Organisation | David Telling Charitable Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2016 |
| End | 12/2018 |
| Description | Testing Radical prostatectomy in men with prostate cancer and oligoMetastases to the bone: a randomised controlled feasibility trial |
| Amount | £183,000 (GBP) |
| Organisation | Prostate Cancer Foundation |
| Sector | Charity/Non Profit |
| Country | Global |
| Start | 10/2015 |
| End | 10/2018 |
| Description | The ANTHEM feasibility study: Is A Novel THErapeutic mammaplasty procedure a safe and effective alternative to Mastectomy for treatment of breast cancer? |
| Amount | £3,527 (GBP) |
| Organisation | Association of Breast Surgery |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | The ANTHEM study: Is A Novel THErapeutic mammaplasty procedure a safe and effective surgical alternative to Mastectomy for treatment of breast cancer? |
| Amount | £99,949 (GBP) |
| Organisation | University Hospitals Bristol NHS Foundation Trust |
| Department | Above and Beyond Grants |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | The BRaveR Study - Methods to develop and deliver Better ReseArch to improVe outcomes and inform practice in brEast Reconstruction |
| Amount | £1,118,847 (GBP) |
| Funding ID | CS-2016-16-019 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| Description | The Bluebelle study: a feasibility study of three wound dressing strategies in eLective and unplanned surgery |
| Amount | £444,264 (GBP) |
| Funding ID | HTA/12/200/04 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2014 |
| End | 06/2016 |
| Description | The MRC ConDuCT-II Hub. Collaboration and iNnovation in DifficUlt and Complex randomised controlled Trials In Invasive procedures |
| Amount | £2,000,000 (GBP) |
| Funding ID | MR/K025643/1 |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 03/2019 |
| Description | The Pre-BRA (Pre-pectoral Breast Reconstruction Evaluation) Study. An IDEAL 2a/2b prospective cohort study to determine the safety and effectiveness of pre-pectoral implant based breast reconstruction |
| Amount | £10,000 (GBP) |
| Organisation | Association of Breast Surgery |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | The Prepare-Me study: a randomised controlled trial of preparation for dialysis or conservative care. |
| Amount | £1,784,741 (GBP) |
| Funding ID | HTA - 15/57/39 |
| Organisation | NIHR Trauma Nework |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2017 |
| End | 07/2022 |
| Description | The Prepare-Me study: a randomised controlled trial of preparation for dialysis or conservative care. |
| Amount | £1,784,741 (GBP) |
| Funding ID | HTA - 15/57/39 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2017 |
| End | 07/2022 |
| Description | The ProtecT study: Prostate testing for cancer and treatment. |
| Amount | £2,656,176 (GBP) |
| Funding ID | HTA/96/20/99 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2014 |
| End | 12/2016 |
| Description | The VIOLET trial - VIdeo assisted thoracoscopic lobectomy versus conventional Open LobEcTomy for lung cancer, a multi-centre randomised controlled trial with an internal pilot |
| Amount | £1,642,978 (GBP) |
| Funding ID | HTA/13/04/03 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2015 |
| End | 10/2020 |
| Description | The choice between hip prosthetic bearing surfaces in total hip replacement: evidence synthesis, statistical analysis and decision modelling to evaluate the effectiveness and cost-effectiveness of prosthetic implants for the NHS. |
| Amount | £230,304 (GBP) |
| Funding ID | PB-PG-0613-31032 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | The iBRA (implant Breast Reconstruction evAluation) study - A prospective multicentre cohort study to inform the feasibility and conduct a pragmatic randomised clinical trial comparing new techniques of implant-based breast reconstruction |
| Amount | £243,418 (GBP) |
| Funding ID | RfPB 0214-33065 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2015 |
| End | 05/2018 |
| Description | The iBRA (implant Breast Reconstruction evAluation) study - A prospective multicentre cohort study to inform the feasibility and conduct a pragmatic randomised clinical trial comparing new techniques of implant-based breast reconstruction. |
| Amount | £249,000 (GBP) |
| Funding ID | PB-PG-0214-33065 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2015 |
| End | 05/2018 |
| Description | To develop a cluster randomised controlled trial to evaluate a consultation-level intervention for frequently attending patients in primary care: The Footprints in Primary Care Study. |
| Amount | £22,266 (GBP) |
| Organisation | Avon Primary Care Research Collaborative |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Training workshops for recruiters to randomised trials. |
| Amount | £28,822 (GBP) |
| Organisation | National Institute for Health Research |
| Department | NIHR Clinical Research Network (CRN) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 03/2017 |
| Description | Treatment effectiveness in multimorbidity: Combining efficacy estimates from clinical trials with the natural history obtained from large routine healthcare databases to determine net overall treatment benefits. |
| Amount | £40,823 (GBP) |
| Funding ID | 201492/Z/16/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 08/2020 |
| Description | Trials Methodology Research Partnership |
| Amount | £383,081 (GBP) |
| Funding ID | MR/S014357/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2019 |
| End | 05/2022 |
| Description | UK Cohort study to Investigate the prevention of Parastomal Hernia (CIPHER) |
| Amount | £1,410,678 (GBP) |
| Funding ID | HTA/14/166/01 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | UK Cohort study to Investigate the prevention of Parastomal Hernia (CIPHER) |
| Amount | £1,041,678 (GBP) |
| Funding ID | HTA/14/166/01 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2016 |
| End | 04/2022 |
| Description | UNBLOCS: laser or saline/bipolar surgery |
| Amount | £1,100,000 (GBP) |
| Funding ID | HTA - 12/35/15 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | UNBLOCS: laser or saline/bipolar surgery. |
| Amount | £1,100,000 (GBP) |
| Funding ID | HTA - 12/35/15 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | UPSTREAM: Urodynamics for Prostate Surgery: randomised Evaluation of Assessment Methods: for diagnosis and management of bladder outlet obstruction of men |
| Amount | £1,224,219 (GBP) |
| Funding ID | HTA - 12/140/01 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Understanding the role of the multidisciplinary team in recruitment to randomised controlled trials: an exploratory qualitative study |
| Amount | £55,000 (GBP) |
| Organisation | Royal College of Surgeons of England |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 10/2015 |
| End | 10/2016 |
| Description | University of Bristol Alumni: Travel award to attend SCT 2018 in U.S. to give oral presentation |
| Amount | £450 (GBP) |
| Organisation | University of Bristol |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 05/2018 |
| End | 05/2018 |
| Description | Upstream (Drake) |
| Amount | £1,108,500 (GBP) |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 03/2017 |
| Description | Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM) for diagnosis and management of bladder outlet obstruction in men |
| Amount | £1,708,002 (GBP) |
| Funding ID | 12/140/01 |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2014 |
| End | 03/2018 |
| Description | Use of Network Meta-analysis to Inform Clinical Parameters in Economic Evaluations. |
| Amount | £1,369 (GBP) |
| Organisation | Canadian Agency for Drugs and Technologies in Health |
| Sector | Public |
| Country | Canada |
| Start | 01/2015 |
| End | 04/2015 |
| Description | Use of breast pumps to improve breastfeeding outcomes: development and feasibility testing of a novel incentive intervention (BABI 1) |
| Amount | £42,669 (GBP) |
| Funding ID | YRSS/PSG/2015/01 |
| Organisation | Glasgow Children's Hospital Charity |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2016 |
| End | 02/2018 |
| Description | User-focused research to identify the benefits of innovative digital recruitment and retention tools for more efficient conduct of randomised trials |
| Amount | £6,270 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 10/2017 |
| End | 09/2018 |
| Description | What are the indications for prescribing antidepressants that will lead to clinical benefit? (PANDA) |
| Amount | £1,999,968 (GBP) |
| Funding ID | RP-PG-0610-10048 |
| Organisation | National Institute for Health Research |
| Department | Programme Grants for Applied Research (PGfAR) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2014 |
| End | 05/2017 |
| Description | What is the optimum strategy for identifying adults and children with coeliac disease? A systematic review and economic models |
| Amount | £348,750 (GBP) |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | What is the value of adaptive designs? Estimating expected value of sample information for adaptive trial designs. |
| Amount | £510,646 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | What might a Global Health Trials Methodology Research Agenda look like? |
| Amount | £14,436 (GBP) |
| Funding ID | N84 |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 09/2016 |
| End | 08/2017 |
| Description | Workshop': Improving the evaluation of medical devices with development of a generic core outcome set: a key stakeholder workshop for industry, innovators, clinicians, trialists, journal editors and health policy makers |
| Amount | £9,938 (GBP) |
| Funding ID | N101 |
| Organisation | Medical Research Council (MRC) |
| Department | MRC Hubs for Trial Methodology Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2018 |
| End | 06/2018 |
| Description | Workshop: Mapping current usage of Health Economic Analysis Plans (HEAPs) |
| Amount | £9,630 (GBP) |
| Funding ID | N65 |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 01/2016 |
| Description | Workshop: Meta-Modelling for Value of Information Calculations Workshop (Workshop on 19th Sept 2014 in Bristol) |
| Amount | £9,160 (GBP) |
| Funding ID | R54 |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 09/2014 |
| Description | A randomised controlled trial to establish the clinical and cost effectiveness of expectant management versus pre-operative imaging with MRCP in patients with symptomatic gallstones undergoing laparoscopic cholecystectomy at low or moderate risk of common bile duct stones: The Sunflower Study. (NIHR HTA Programme grant) |
| Organisation | Leeds Teaching Hospitals NHS Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | C Rogers, K Avery, J Blazeby, W Hollingworth, N Blencowe, and L Culliford are co-applicants on grant and K Avery PPI lead. |
| Collaborator Contribution | Leading and conducting the study |
| Impact | None yet |
| Start Year | 2017 |
| Description | A systematic review of the ORRCA database for methods to improve recruitment for unplanned hospital admissions |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We will be performing a systematic review of all articles included in the ORRCA database with the aim of identifying those studies which focus on recruitment of unplanned hospital admissions to randomised controlled trials. Alongside this, our department continues to contribute to screening and categorising ORRCA articles, as part of the ongoing development of the ORRCA resource. |
| Collaborator Contribution | The above departments conceptualised and designed the ORRCA database (http://www.orrca.org.uk). They have been responsible for the development of the protocol, search strategy/process and screening processes and all other activities required to form the database. |
| Impact | None yet |
| Start Year | 2016 |
| Description | A systematic review of the ORRCA database for methods to improve recruitment for unplanned hospital admissions |
| Organisation | Queen's University Belfast |
| Department | School of Medicine, Dentistry and Biomedical Sciences |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We will be performing a systematic review of all articles included in the ORRCA database with the aim of identifying those studies which focus on recruitment of unplanned hospital admissions to randomised controlled trials. Alongside this, our department continues to contribute to screening and categorising ORRCA articles, as part of the ongoing development of the ORRCA resource. |
| Collaborator Contribution | The above departments conceptualised and designed the ORRCA database (http://www.orrca.org.uk). They have been responsible for the development of the protocol, search strategy/process and screening processes and all other activities required to form the database. |
| Impact | None yet |
| Start Year | 2016 |
| Description | A systematic review of the ORRCA database for methods to improve recruitment for unplanned hospital admissions |
| Organisation | University of Aberdeen |
| Department | Health Services Research Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We will be performing a systematic review of all articles included in the ORRCA database with the aim of identifying those studies which focus on recruitment of unplanned hospital admissions to randomised controlled trials. Alongside this, our department continues to contribute to screening and categorising ORRCA articles, as part of the ongoing development of the ORRCA resource. |
| Collaborator Contribution | The above departments conceptualised and designed the ORRCA database (http://www.orrca.org.uk). They have been responsible for the development of the protocol, search strategy/process and screening processes and all other activities required to form the database. |
| Impact | None yet |
| Start Year | 2016 |
| Description | A systematic review of the ORRCA database for methods to improve recruitment for unplanned hospital admissions |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We will be performing a systematic review of all articles included in the ORRCA database with the aim of identifying those studies which focus on recruitment of unplanned hospital admissions to randomised controlled trials. Alongside this, our department continues to contribute to screening and categorising ORRCA articles, as part of the ongoing development of the ORRCA resource. |
| Collaborator Contribution | The above departments conceptualised and designed the ORRCA database (http://www.orrca.org.uk). They have been responsible for the development of the protocol, search strategy/process and screening processes and all other activities required to form the database. |
| Impact | None yet |
| Start Year | 2016 |
| Description | A systematic review of the ORRCA database for methods to improve recruitment for unplanned hospital admissions |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We will be performing a systematic review of all articles included in the ORRCA database with the aim of identifying those studies which focus on recruitment of unplanned hospital admissions to randomised controlled trials. Alongside this, our department continues to contribute to screening and categorising ORRCA articles, as part of the ongoing development of the ORRCA resource. |
| Collaborator Contribution | The above departments conceptualised and designed the ORRCA database (http://www.orrca.org.uk). They have been responsible for the development of the protocol, search strategy/process and screening processes and all other activities required to form the database. |
| Impact | None yet |
| Start Year | 2016 |
| Description | Advisor to NIHR fellowship application |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Advice during application development and will sit on advisory board if funded. |
| Collaborator Contribution | Advice during application development and will sit on advisory board if funded. |
| Impact | multi-disciplinary - Biostats |
| Start Year | 2016 |
| Description | Advisory for trial conduct (PACE study) |
| Organisation | Institute of Cancer Research UK |
| Department | Cancer Research UK Cancer Therapeutics Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Advice on trial conduct. |
| Collaborator Contribution | leading and conducting the study. |
| Impact | multi-disciplinary - Surgery/radiotherapy/Prostate Cancer specialists |
| Start Year | 2016 |
| Description | Application of PIC to evaluate informed consent consultations within the OPTIMISE Trial |
| Organisation | University of Cambridge |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Julia Wade to advise on application of the PIC measure of informed consent |
| Collaborator Contribution | Provision of informed consent consultation data from the OPTIMISE trial to enable further development of PIC tool. |
| Impact | Not known |
| Start Year | 2018 |
| Description | Ashma Krishan PhD |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | My input: supervision |
| Collaborator Contribution | N/A |
| Impact | No outputs or impacts yet |
| Start Year | 2015 |
| Description | Attitudes to Surgical Research Collaboratives Survey |
| Organisation | Northwest Research Collaborative |
| Sector | Charity/Non Profit |
| PI Contribution | Athene Lane, Karen Coulman and Clare Clement providing expertise on questionnaire design, implementation and analysis |
| Collaborator Contribution | Leading and conducting the study. |
| Impact | Not known |
| Start Year | 2017 |
| Description | Becky Boucher fellowship |
| Organisation | University of Leicester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Provide advice on statistical methodology |
| Collaborator Contribution | Fellowship programme of work, publications |
| Impact | None yet, just startaed |
| Start Year | 2014 |
| Description | CEDAR Peers Supporting Physical Activity |
| Organisation | Cardiff University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Economic analysis |
| Collaborator Contribution | Economic analysis |
| Impact | N/A |
| Start Year | 2015 |
| Description | COMET Choice of moisturizer in eczema treatment. Alane investigator on study. |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Intellectual input |
| Collaborator Contribution | Intellectual input and conducting of research |
| Impact | None as yet |
| Start Year | 2013 |
| Description | COMET initiative |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Contributed to a grant proposal to implement research guidelines |
| Collaborator Contribution | Developed and submitted the grant proposal |
| Impact | Grant was rejected |
| Start Year | 2015 |
| Description | CONservative TReatment of Appendicitis in Children - a randomised controlled Trial - CONTRACT (Feasibility study |
| Organisation | Alder Hey Children's NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Esther Crawley is a co-applicant. Lucy Beasant will be conducting interviews. Both Lucy and Esther Crawley helped write the application focusing on the preference elements. |
| Collaborator Contribution | Nigel Hall. National Institute for Health Research (NIHR) Health Technology Assessment |
| Impact | None yet |
| Start Year | 2016 |
| Description | CONservative TReatment of Appendicitis in Children - a randomised controlled Trial - CONTRACT (Feasibility study |
| Organisation | Great Ormond Street Hospital (GOSH) |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Esther Crawley is a co-applicant. Lucy Beasant will be conducting interviews. Both Lucy and Esther Crawley helped write the application focusing on the preference elements. |
| Collaborator Contribution | Nigel Hall. National Institute for Health Research (NIHR) Health Technology Assessment |
| Impact | None yet |
| Start Year | 2016 |
| Description | CONservative TReatment of Appendicitis in Children - a randomised controlled Trial - CONTRACT (Feasibility study |
| Organisation | St George's University Hospitals NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Esther Crawley is a co-applicant. Lucy Beasant will be conducting interviews. Both Lucy and Esther Crawley helped write the application focusing on the preference elements. |
| Collaborator Contribution | Nigel Hall. National Institute for Health Research (NIHR) Health Technology Assessment |
| Impact | None yet |
| Start Year | 2016 |
| Description | CONservative TReatment of Appendicitis in Children - a randomised controlled Trial - CONTRACT (Feasibility study |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Esther Crawley is a co-applicant. Lucy Beasant will be conducting interviews. Both Lucy and Esther Crawley helped write the application focusing on the preference elements. |
| Collaborator Contribution | Nigel Hall. National Institute for Health Research (NIHR) Health Technology Assessment |
| Impact | None yet |
| Start Year | 2016 |
| Description | CONservative TReatment of Appendicitis in Children - a randomised controlled Trial - CONTRACT (Feasibility study |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Esther Crawley is a co-applicant. Lucy Beasant will be conducting interviews. Both Lucy and Esther Crawley helped write the application focusing on the preference elements. |
| Collaborator Contribution | Nigel Hall. National Institute for Health Research (NIHR) Health Technology Assessment |
| Impact | None yet |
| Start Year | 2016 |
| Description | COPD bundles study (NIHR) |
| Organisation | North Bristol NHS Trust |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Statistical and clinical trials methodology expertise |
| Collaborator Contribution | Strategy and organisation behaviour, emergency and critical care research, clinical expertise |
| Impact | http://www.ncbi.nlm.nih.gov/pubmed/26916196 |
| Start Year | 2014 |
| Description | COPD bundles study (NIHR) |
| Organisation | Sue Jenkins & Associates |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Statistical and clinical trials methodology expertise |
| Collaborator Contribution | Strategy and organisation behaviour, emergency and critical care research, clinical expertise |
| Impact | http://www.ncbi.nlm.nih.gov/pubmed/26916196 |
| Start Year | 2014 |
| Description | COPD bundles study (NIHR) |
| Organisation | University of the West of England |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Statistical and clinical trials methodology expertise |
| Collaborator Contribution | Strategy and organisation behaviour, emergency and critical care research, clinical expertise |
| Impact | http://www.ncbi.nlm.nih.gov/pubmed/26916196 |
| Start Year | 2014 |
| Description | COS-STAR |
| Organisation | University of Liverpool |
| Department | Institute of Translational Medicine |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Completion of 2 surveys and participation in a 1 day consensus meeting. This will lead to guidelines publication |
| Collaborator Contribution | Organisation of the work |
| Impact | None yet |
| Start Year | 2016 |
| Description | Collaboration: Methodological challenges in healthcare resource-use measurement: towards good practice |
| Organisation | Maastricht University (UM) |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Organised session at 10th iHEA/ECHE Congress, Dublin (July 2014) |
| Collaborator Contribution | Organised session at 10th iHEA/ECHE Congress, Dublin (July 2014) |
| Impact | . |
| Start Year | 2014 |
| Description | Collaborator: MRC-MRP bid to develop a SPIRIT-PRO Extension, web based training tool and guidance for ethics committees |
| Organisation | University of Birmingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | This is a short-listed bid - funding not yet confirmed. |
| Collaborator Contribution | Contributions has been commenting on bid. |
| Impact | Outcomes still in progress. |
| Start Year | 2014 |
| Description | Collaborator: MRC-MRP bid to develop a SPIRIT-PRO Extension, web based training tool and guidance for ethics committees |
| Organisation | University of Birmingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | This is a short-listed bid - funding not yet confirmed. Contributions has been commenting on bid |
| Collaborator Contribution | Development of bid |
| Impact | none yet |
| Start Year | 2014 |
| Description | Consideration of an independent evaluation of the QRI as a SWA |
| Organisation | University of York |
| Department | York Trials Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Nicola Mills is leading the Bristol input |
| Collaborator Contribution | Connections made between Bristol and York Unis to evaluate ConduCT-II/QuinteT recruitment workshops as a SWAT |
| Impact | Unknown |
| Start Year | 2018 |
| Description | Developing and sharing methods to improve Informed COnsent in clinical trials in low- and middle-income settings: India-Vietnam-UK interdisciplinary Network (ICONet) |
| Organisation | King Edward Memorial Hospital |
| Country | Australia |
| Sector | Hospitals |
| PI Contribution | Sangeetha Paramasivan is the co-lead for project proposal |
| Collaborator Contribution | Trialists, social scientists, methodologists, ethicists, clinicians |
| Impact | None yet |
| Start Year | 2019 |
| Description | Developing guidelines for use of trial registry data in systematic reviews |
| Organisation | University of Saskatchewan |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Jelena Savovic was senior methodological advisor. |
| Collaborator Contribution | Julia Bidonde and Jose Menezes-Echavez (Norwegian Institute) and Catherine Boden (Saskatchewan) all performed the data collection for a systematic review. |
| Impact | Not known |
| Start Year | 2017 |
| Description | Development and feasibility cluster randomised controlled trial of a Peer-Led physical Activity iNtervention for Adolescent girls (Plan-A) |
| Organisation | Swansea University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research expertise |
| Collaborator Contribution | Research expertise |
| Impact | None yet |
| Start Year | 2015 |
| Description | Development of online training kit for RCT recruiters |
| Organisation | NIHR London (South) CRN |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Developing the online training using data and advice from Bristol |
| Collaborator Contribution | Mills and Rooshenas are co-leading the Bristol input |
| Impact | Online training tool for RCT recruitment |
| Start Year | 2018 |
| Description | Discussions to offer recruitment training to Swedish bariatrics |
| Organisation | University of Gothenburg |
| Country | Sweden |
| Sector | Academic/University |
| PI Contribution | Mills is leading the Bristol input |
| Collaborator Contribution | Connection made with Bristol team to discuss training recruiters to the BEST RCT |
| Impact | Unknown |
| Start Year | 2018 |
| Description | EVSI for adaptive designs |
| Organisation | Newcastle University |
| Department | Academic Psychiatry and Regional Affective Disorders Service |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Joined the HTMR working group on adaptive designs. Preparing grant to submit grant (NIRG) proposal to MRC |
| Collaborator Contribution | Leads work. |
| Impact | Unknown |
| Start Year | 2018 |
| Description | EVSI for adaptive designs |
| Organisation | University of Cambridge |
| Department | Cambridge University Health Partners |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Joined the HTMR working group on adaptive designs. Preparing grant to submit grant (NIRG) proposal to MRC |
| Collaborator Contribution | Leads work. |
| Impact | Unknown |
| Start Year | 2018 |
| Description | EVSI for adaptive designs |
| Organisation | University of Oxford |
| Department | Wolfson College |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Joined the HTMR working group on adaptive designs. Preparing grant to submit grant (NIRG) proposal to MRC |
| Collaborator Contribution | Leads work. |
| Impact | Unknown |
| Start Year | 2018 |
| Description | EVSI for adaptive designs |
| Organisation | University of Pittsburgh |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Joined the HTMR working group on adaptive designs. Preparing grant to submit grant (NIRG) proposal to MRC |
| Collaborator Contribution | Leads work. |
| Impact | Unknown |
| Start Year | 2018 |
| Description | EVSI for adaptive designs |
| Organisation | University of Sheffield |
| Department | University of Sheffield, Tissue resource |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Joined the HTMR working group on adaptive designs. Preparing grant to submit grant (NIRG) proposal to MRC |
| Collaborator Contribution | Leads work. |
| Impact | Unknown |
| Start Year | 2018 |
| Description | Examining the influence of an informational video on participant retention in a randomised controlled trial. |
| Organisation | National University of Ireland, Galway |
| Country | Ireland |
| Sector | Academic/University |
| PI Contribution | Clare Clement will advise on SWAT design, implementation and analysis |
| Collaborator Contribution | Leading and conducting the study. |
| Impact | Not known |
| Start Year | 2017 |
| Description | Extending ORRCA to create a central resource for retention research within clinical trials (ORRCA 2) |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Athene Lane will provide expertise in trial recruitment and retention |
| Collaborator Contribution | Expertise in clinical trials methodology |
| Impact | None yet |
| Start Year | 2018 |
| Description | FOOTPRINTS in primary care study (NIHR RfPB) |
| Organisation | Frome Valley Health Ltd |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Statistical and clinical trials methodology expertise |
| Collaborator Contribution | Clinical expertise |
| Impact | None yet |
| Start Year | 2014 |
| Description | Fellowship (DM) |
| Organisation | University of Glasgow |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Statistical expertise |
| Collaborator Contribution | Leads work |
| Impact | Not known |
| Start Year | 2015 |
| Description | Fellowship (SD) |
| Organisation | Medical Research Council (MRC) |
| Department | MRC North West Hub for Trials Methodology Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Advising on work and providing statistical expertise |
| Collaborator Contribution | Leading the work and doing the analyses |
| Impact | Not known |
| Start Year | 2016 |
| Description | Fellowship (TS) |
| Organisation | University of East Anglia |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Attendance at annual advisory group meeting and regular mentoring teleconferences |
| Collaborator Contribution | Leads work |
| Impact | Not known |
| Start Year | 2015 |
| Description | General Practioners and Emergency Departments (GPED): Efficient models of care |
| Organisation | NHS Bristol CCG |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Co-Investigator |
| Collaborator Contribution | CCG hosts the trial, UWE leads the trial, York does economics and statistics and Newcastle leads qualitative research. |
| Impact | Not known |
| Start Year | 2017 |
| Description | General Practioners and Emergency Departments (GPED): Efficient models of care |
| Organisation | Newcastle University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-Investigator |
| Collaborator Contribution | CCG hosts the trial, UWE leads the trial, York does economics and statistics and Newcastle leads qualitative research. |
| Impact | Not known |
| Start Year | 2017 |
| Description | General Practioners and Emergency Departments (GPED): Efficient models of care |
| Organisation | University of York |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-Investigator |
| Collaborator Contribution | CCG hosts the trial, UWE leads the trial, York does economics and statistics and Newcastle leads qualitative research. |
| Impact | Not known |
| Start Year | 2017 |
| Description | General Practioners and Emergency Departments (GPED): Efficient models of care |
| Organisation | University of the West of England |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-Investigator |
| Collaborator Contribution | CCG hosts the trial, UWE leads the trial, York does economics and statistics and Newcastle leads qualitative research. |
| Impact | Not known |
| Start Year | 2017 |
| Description | HEAPS Workshop |
| Organisation | University of Oxford |
| Department | Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Economic analysis |
| Collaborator Contribution | Economic analysis |
| Impact | No outputs yet |
| Start Year | 2015 |
| Description | HTMR Recruitment to Trials Working Group membership |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | collaborative work to identify priority areas to improve trial recruitment - involvement includes contribution to discussions, research dissemination and workshop design and delivery |
| Collaborator Contribution | collaborative work to identify priority areas to improve trial recruitment - involvement includes contribution to discussions, research dissemination and workshop design and delivery (as above as this is collaborative work). Funding for workshops. |
| Impact | Outcomes: Two workshops funded and run; "Developing, delivering and evaluating training courses for recruiters to randomised trials" and two-day workshop on "the design and analysis of clinical trials in head and neck cancer". Educational impact. Multidisciplinary: health services research, clinical, academic, quantitative research, qualitative research |
| Start Year | 2011 |
| Description | Health Informatics: Use of the electronic health record in the design and conduct of clinical trials. (MRC HTMR) |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Clinical Trials methodology expertise |
| Collaborator Contribution | Statistical expertise |
| Impact | Not known |
| Start Year | 2014 |
| Description | IDEAL-D collaboration |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | International consensus process to develop research guidelines |
| Collaborator Contribution | International consensus process to develop research guidelines |
| Impact | No impacts yet |
| Start Year | 2014 |
| Description | ISRUM (Items for a standardised resource-use measure) |
| Organisation | University of Oxford |
| Department | Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Economic analysis |
| Collaborator Contribution | Economic analysis |
| Impact | No outputs yet |
| Start Year | 2015 |
| Description | Identifying and critiquing different approaches to developing complex interventions (INDEX study) |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Contribution of new and original thinking on research methods relating to intervention development and writing a grant application |
| Collaborator Contribution | Partners contributed to discussions, literature reviewing and grant application writing |
| Impact | None yet |
| Start Year | 2016 |
| Description | Identifying and critiquing different approaches to developing complex interventions (INDEX study) |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Contribution of new and original thinking on research methods relating to intervention development and writing a grant application |
| Collaborator Contribution | Partners contributed to discussions, literature reviewing and grant application writing |
| Impact | None yet |
| Start Year | 2016 |
| Description | Identifying and critiquing different approaches to developing complex interventions (INDEX study) |
| Organisation | University of Stirling |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Contribution of new and original thinking on research methods relating to intervention development and writing a grant application |
| Collaborator Contribution | Partners contributed to discussions, literature reviewing and grant application writing |
| Impact | None yet |
| Start Year | 2016 |
| Description | Identifying the Quality Indicators of a Patient-Centred Trial: obtaining expert consensus using the Delphi method |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research expertise |
| Collaborator Contribution | Research expertise |
| Impact | Not known |
| Start Year | 2015 |
| Description | Improving the management of patients with multimorbidity in general practice |
| Organisation | University of Manchester |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research expertise |
| Collaborator Contribution | Research expertise |
| Impact | Not known |
| Start Year | 2014 |
| Description | Inform: Infection after total joint replacement. (NIHR PGfAR) |
| Organisation | Cardiff and Vale University Health Board |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Clinical Trials methodology expertise |
| Collaborator Contribution | Clinical expertise |
| Impact | One-stage or two-stage revision surgery for prosthetic hip joint infection - the INFORM trial: a study protocol for a randomised controlled trial Simon Strange, Michael R. Whitehouse, Andrew D. Beswick, Tim Board, Amanda Burston, Ben Burston, Fran E. Carroll, Paul Dieppe, Kirsty Garfield, Rachael Gooberman-Hill, Stephen Jones, Setor Kunutsor, Athene Lane, Erik Lenguerrand, Alasdair MacGowan, Andrew Moore, Sian Noble, Joanne Simon, Ian Stockley, Adrian H. Taylor, Andrew Toms, Jason Webb, John-Paul Whittaker, Matthew Wilson, Vikki Wylde, and Ashley W. Blom |
| Start Year | 2014 |
| Description | Inform: Infection after total joint replacement. (NIHR PGfAR) |
| Organisation | North Bristol NHS Trust |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Clinical Trials methodology expertise |
| Collaborator Contribution | Clinical expertise |
| Impact | One-stage or two-stage revision surgery for prosthetic hip joint infection - the INFORM trial: a study protocol for a randomised controlled trial Simon Strange, Michael R. Whitehouse, Andrew D. Beswick, Tim Board, Amanda Burston, Ben Burston, Fran E. Carroll, Paul Dieppe, Kirsty Garfield, Rachael Gooberman-Hill, Stephen Jones, Setor Kunutsor, Athene Lane, Erik Lenguerrand, Alasdair MacGowan, Andrew Moore, Sian Noble, Joanne Simon, Ian Stockley, Adrian H. Taylor, Andrew Toms, Jason Webb, John-Paul Whittaker, Matthew Wilson, Vikki Wylde, and Ashley W. Blom |
| Start Year | 2014 |
| Description | Inform: Infection after total joint replacement. (NIHR PGfAR) |
| Organisation | Oxford University Hospitals NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Clinical Trials methodology expertise |
| Collaborator Contribution | Clinical expertise |
| Impact | One-stage or two-stage revision surgery for prosthetic hip joint infection - the INFORM trial: a study protocol for a randomised controlled trial Simon Strange, Michael R. Whitehouse, Andrew D. Beswick, Tim Board, Amanda Burston, Ben Burston, Fran E. Carroll, Paul Dieppe, Kirsty Garfield, Rachael Gooberman-Hill, Stephen Jones, Setor Kunutsor, Athene Lane, Erik Lenguerrand, Alasdair MacGowan, Andrew Moore, Sian Noble, Joanne Simon, Ian Stockley, Adrian H. Taylor, Andrew Toms, Jason Webb, John-Paul Whittaker, Matthew Wilson, Vikki Wylde, and Ashley W. Blom |
| Start Year | 2014 |
| Description | Inform: Infection after total joint replacement. (NIHR PGfAR) |
| Organisation | Royal Devon and Exeter NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Clinical Trials methodology expertise |
| Collaborator Contribution | Clinical expertise |
| Impact | One-stage or two-stage revision surgery for prosthetic hip joint infection - the INFORM trial: a study protocol for a randomised controlled trial Simon Strange, Michael R. Whitehouse, Andrew D. Beswick, Tim Board, Amanda Burston, Ben Burston, Fran E. Carroll, Paul Dieppe, Kirsty Garfield, Rachael Gooberman-Hill, Stephen Jones, Setor Kunutsor, Athene Lane, Erik Lenguerrand, Alasdair MacGowan, Andrew Moore, Sian Noble, Joanne Simon, Ian Stockley, Adrian H. Taylor, Andrew Toms, Jason Webb, John-Paul Whittaker, Matthew Wilson, Vikki Wylde, and Ashley W. Blom |
| Start Year | 2014 |
| Description | Inform: Infection after total joint replacement. (NIHR PGfAR) |
| Organisation | Sheffield Teaching Hospitals NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Clinical Trials methodology expertise |
| Collaborator Contribution | Clinical expertise |
| Impact | One-stage or two-stage revision surgery for prosthetic hip joint infection - the INFORM trial: a study protocol for a randomised controlled trial Simon Strange, Michael R. Whitehouse, Andrew D. Beswick, Tim Board, Amanda Burston, Ben Burston, Fran E. Carroll, Paul Dieppe, Kirsty Garfield, Rachael Gooberman-Hill, Stephen Jones, Setor Kunutsor, Athene Lane, Erik Lenguerrand, Alasdair MacGowan, Andrew Moore, Sian Noble, Joanne Simon, Ian Stockley, Adrian H. Taylor, Andrew Toms, Jason Webb, John-Paul Whittaker, Matthew Wilson, Vikki Wylde, and Ashley W. Blom |
| Start Year | 2014 |
| Description | Inform: Infection after total joint replacement. (NIHR PGfAR) |
| Organisation | The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Clinical Trials methodology expertise |
| Collaborator Contribution | Clinical expertise |
| Impact | One-stage or two-stage revision surgery for prosthetic hip joint infection - the INFORM trial: a study protocol for a randomised controlled trial Simon Strange, Michael R. Whitehouse, Andrew D. Beswick, Tim Board, Amanda Burston, Ben Burston, Fran E. Carroll, Paul Dieppe, Kirsty Garfield, Rachael Gooberman-Hill, Stephen Jones, Setor Kunutsor, Athene Lane, Erik Lenguerrand, Alasdair MacGowan, Andrew Moore, Sian Noble, Joanne Simon, Ian Stockley, Adrian H. Taylor, Andrew Toms, Jason Webb, John-Paul Whittaker, Matthew Wilson, Vikki Wylde, and Ashley W. Blom |
| Start Year | 2014 |
| Description | Inform: Infection after total joint replacement. (NIHR PGfAR) |
| Organisation | University of Exeter |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Clinical Trials methodology expertise |
| Collaborator Contribution | Clinical expertise |
| Impact | One-stage or two-stage revision surgery for prosthetic hip joint infection - the INFORM trial: a study protocol for a randomised controlled trial Simon Strange, Michael R. Whitehouse, Andrew D. Beswick, Tim Board, Amanda Burston, Ben Burston, Fran E. Carroll, Paul Dieppe, Kirsty Garfield, Rachael Gooberman-Hill, Stephen Jones, Setor Kunutsor, Athene Lane, Erik Lenguerrand, Alasdair MacGowan, Andrew Moore, Sian Noble, Joanne Simon, Ian Stockley, Adrian H. Taylor, Andrew Toms, Jason Webb, John-Paul Whittaker, Matthew Wilson, Vikki Wylde, and Ashley W. Blom |
| Start Year | 2014 |
| Description | Inform: Infection after total joint replacement. (NIHR PGfAR) |
| Organisation | Wrightington, Wigan and Leigh NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Clinical Trials methodology expertise |
| Collaborator Contribution | Clinical expertise |
| Impact | One-stage or two-stage revision surgery for prosthetic hip joint infection - the INFORM trial: a study protocol for a randomised controlled trial Simon Strange, Michael R. Whitehouse, Andrew D. Beswick, Tim Board, Amanda Burston, Ben Burston, Fran E. Carroll, Paul Dieppe, Kirsty Garfield, Rachael Gooberman-Hill, Stephen Jones, Setor Kunutsor, Athene Lane, Erik Lenguerrand, Alasdair MacGowan, Andrew Moore, Sian Noble, Joanne Simon, Ian Stockley, Adrian H. Taylor, Andrew Toms, Jason Webb, John-Paul Whittaker, Matthew Wilson, Vikki Wylde, and Ashley W. Blom |
| Start Year | 2014 |
| Description | Investigating the effectiveness and cost effectiveness of using FITNET to treat paediatric CFS/ME in the UK |
| Organisation | Radboud University Nijmegen |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Nicola Mills will oversee the qualitative research to understand and address recruitment difficulties. Bristol will lead the main study. Disciplines include clinical, health economics, social science, health care evaluation. |
| Collaborator Contribution | Research expertise |
| Impact | None yet |
| Start Year | 2015 |
| Description | Investigating the effectiveness and cost effectiveness of using FITNET to treat paediatric CFS/ME in the UK |
| Organisation | University of Bath |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Nicola Mills will oversee the qualitative research to understand and address recruitment difficulties. Bristol will lead the main study. Disciplines include clinical, health economics, social science, health care evaluation. |
| Collaborator Contribution | Research expertise |
| Impact | None yet |
| Start Year | 2015 |
| Description | Joint Trial Steering Committee project |
| Organisation | Medical Research Council (MRC) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Athene Lane collaborating with UCL partners to develop recommendations for conduct of TSCs and deliver a workshop with the NIHR HTA. |
| Collaborator Contribution | Carol Gamble Liverpool and Matt Sydes UCL as Athene Lane. |
| Impact | multi-disciplinary |
| Start Year | 2016 |
| Description | Laura Flight fellowship |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | My input: expert advisory panel member |
| Collaborator Contribution | N/A |
| Impact | No outputs or impacts yet |
| Start Year | 2015 |
| Description | Losing the losses: understanding the reasons for attrition in RCTs and developing the evidence to prevent it. (MRC MRP) |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Clinical Trials methodology expertise |
| Collaborator Contribution | Statistical expertise |
| Impact | Not known |
| Start Year | 2014 |
| Description | MRC HTMR: Trial Forge: A Lane |
| Organisation | University of Aberdeen |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Intellectual input |
| Collaborator Contribution | Intellectual input and networking with other methodologists to raise awareness of initiative. |
| Impact | None as yet |
| Start Year | 2014 |
| Description | MRC TMRP Trial Conduct |
| Organisation | Medical Research Council (MRC) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Members of working group |
| Collaborator Contribution | Advice on priority setting and ideas for future research |
| Impact | None yet |
| Start Year | 2019 |
| Description | MRC Trials Methodology Research Partnership |
| Organisation | University of Leeds |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-lead |
| Collaborator Contribution | Co-leads |
| Impact | Multidisciplinary. Trialists, social scientist, methodologist |
| Start Year | 2019 |
| Description | MRC Trials Methodology Research Partnership |
| Organisation | University of Liverpool |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-lead |
| Collaborator Contribution | Co-leads |
| Impact | Multidisciplinary. Trialists, social scientist, methodologist |
| Start Year | 2019 |
| Description | MRC Trials Methodology Research Partnership |
| Organisation | University of Oxford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Co-lead |
| Collaborator Contribution | Co-leads |
| Impact | Multidisciplinary. Trialists, social scientist, methodologist |
| Start Year | 2019 |
| Description | Methodology and development of Core Outcome Sets / Core Information Sets |
| Organisation | European Commission |
| Department | Seventh Framework Programme (FP7) |
| Country | European Union (EU) |
| Sector | Public |
| PI Contribution | Contributed to workshop facilitation, presentation at COMET PPI workshop, teleconferences discussion about optimal methodology |
| Collaborator Contribution | Guidance on methodology, generated and facilitated workshops, sharing of expertise |
| Impact | Presentation at COMET PPI workshop Presentation and help with facilitation of COMET methodological workshop Multi-disciplinary: statisticians, trial methodologists, health professionals |
| Start Year | 2012 |
| Description | Model Based Network Meta-Analysis |
| Organisation | Pfizer Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Successful MRC grant, that is just about to begin. Pfizer bring model based meta-analysis expertise, and Bristol bring network meta-analysis skills. Funds come jointly from MRC MICA Methodology Research grant and from pfizer. |
| Collaborator Contribution | Pfizer bring model based meta-analysis expertise and access to datasets and relevant examples. |
| Impact | MRC MICA grant |
| Start Year | 2014 |
| Description | Model based network meta-analysis |
| Organisation | Pfizer Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Leading the research project |
| Collaborator Contribution | Statistical expertise, applied datasets, industry perspective. Part-fund a researcher |
| Impact | Not known |
| Start Year | 2014 |
| Description | NAP SACC Feasibility Trial |
| Organisation | North Somerset Council |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Economic analysis |
| Collaborator Contribution | Economic analysis |
| Impact | N/A |
| Start Year | 2014 |
| Description | Needle fasciotomy versus limited fasciectomy for the treatment of Dupuytren's |
| Organisation | Wiltshire County Council |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Economic analysis |
| Collaborator Contribution | Economic analysis |
| Impact | No outputs yet |
| Start Year | 2015 |
| Description | Optimal Personalised Treatment of early breast cancer usIng Multi-parameter Analysis |
| Organisation | Cambridge University Hospitals NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Research expertise |
| Collaborator Contribution | Research and clinical expertise |
| Impact | Not known |
| Start Year | 2015 |
| Description | Optimal Personalised Treatment of early breast cancer usIng Multi-parameter Analysis |
| Organisation | King's College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Research expertise |
| Collaborator Contribution | Research and clinical expertise |
| Impact | Not known |
| Start Year | 2015 |
| Description | |