Centre for Cognitive Ageing & Cognitive Epidemiology

Lead Research Organisation: University of Edinburgh
Department Name: Centre Cogn Ageing and Cogn Epidemiology

Abstract

In 2008 we formed the Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE) at the University of Edinburgh. This brought together a diverse range of scientists-epidemiologists, psychologists, geriatricians, clinical and basic neuroscientists, geneticists, statisticians, sociologists-to study how the brain and the body influence each other across the human life course and between generations. This application describes how CCACE enhanced this important research, and our plans for the next five years.

The Centre brought a step change in our scientific achievements, our training of young scientists, and the communication of our research to wider, non-scientific groups. In science, we made achievements in four areas. (1) Our discoveries made us the leading international centre for the study of how intelligence from youth influences physical health, wellbeing, mental illness and mortality later in life (cognitive epidemiology). (2) In our large groups of older people on whom there were measures of intelligence from youth we made discoveries about genetic, lifestyle, brain structure and other contributions to the ageing of thinking (cognitive) skills that put us at the forefront internationally. Our discoveries on how diabetes affects thinking skills are based on one of the largest studies. (3) Our work uses theories of how the brain works to explore ageing effects on important specific thinking skills. This led to our devising tests for the early detection of dementia. (4) Our scientists working on the biological mechanisms of cognitive decline have made discoveries in human and animal studies that revealed likely biological routes for the amelioration of cognitive ageing. The Centre's presence brought new collaborators, gave us the capability to lead new cohorts and international consortia, and brought in a new Alzheimer Research Centre.

The Centre brought a step change in the training of young scientists. The thriving mix of successful scientists working together has built up a community of PhD students concentrating on our aims. Many who are not funded by the Centre have come under our umbrella, adding value. We are meeting a need for the training of clinical scientists in our areas. The Centre has also been responsible for a step change in knowledge exchange. Our work with lay people, policy makers, artists, and business has brought our science out of the office and laboratory, creating awareness, new art, and products, and influencing policy.

In the next five years the University of Edinburgh is generously supporting the Centre by funding a substantial amount of what originally came from LLHW funding. In research training, our vision is to mentor young scientists from the end of their PhDs and helpi them to develop into independent scientists in cognitive ageing and cognitive epidemiology to meet these important needs. In our four research Groups' fields we highlight the key areas in which we aim to make discoveries. Here, we mention a few. We are expanding our cognitive epidemiology work to examine how personality and thinking skills affect later health and illness. We shall conduct large-scale new genetic work in our cohorts of older people to find out how people's environments affect how their genes switch on and off and thereby affect thinking skills and other aspects of ageing. We shall conduct unusually large longitudinal studies to examine the parallel changes in brain scans and thinking skills, and the changes in cognition over 10 years in people with type 2 diabetes. We shall delve into specific thinking processes to find the precise sets of problems that best characterise various forms of normal and illness-based cognitive ageing. We shall undertake parallel human and animal work to investigate the importance and nature of changes in small blood vessels for brain health and thinking skills. We have an ambitious strategy for an expanded and more formalised programme of knowledge exchange.

Technical Summary

The Centre will: (1) elucidate the routes to the vulnerable ageing brain; (2) find mechanisms by which lower cognitive ability makes the body vulnerable to ill health; (3) provide an outstanding environment for interdisciplinary research training.

In research training:
Mentor a new cohort of post-doctoral scientists.
Expand our cohort of interdisciplinary PhD students.
Expand our training of medical scientists.

In cognitive epidemiology:
Expand it to include non-cognitive traits.
Conduct individual participant meta-analyses.
Use new datasets to test mechanistic hypotheses.

In cohort work on cognitive ageing:
Expand work on the Lothian Birth Cohorts and Edinburgh type 2 Diabetes Study.
Test genetic and environmental influences on cognitive change from childhood to old age and in old age.
Test determinants of cognitive change across 10 years in type 2 diabetes.
Conduct longitudinal genome-wide methylation studies.
Conduct genome-wide expression studies.
Test associations between the human brain connectome and cognitive functions.
Lead international consortia on GWAS, exome chip, and methylation studies of cognition, novel brain imaging and other phenotypes.

In experimental work on cognitive ageing:
Complete regulatory approval for Alzheimer diagnostic tests.
Use brain imaging to explore why some cognitive functions are preserved with age.
Identify cognitive signatures that identify those likely to convert to dementia.
Explore the relationship between the design and use of digital memory systems and our research on age-impaired forgetting and multitasking.

In mechanisms of cognitive ageing:
Investigate how stress and glucocorticoids influence cognitive ageing and test therapeutic strategies.
In cerebral small vessel disease test the importance of vascular integrity, inflammation and oxidative stress for ageing brain integrity.
Understand how brain injury occurring in the context of acute systemic illness can alter cognitive decline.

Planned Impact

We described above that a wide range of academics benefit from our research. Our research on the determinants of cognitive ageing and the factors that promote bodily health through life are of very wide public and professional interest. The non-academic beneficiaries of this work will be older people, care providers, the wider general public, public health providers, policy makers, third sector organisations, and business. Of those organisations mentioned in the guidance notes, our work already appears in Science Museums in London and Glasgow and we are in regular contact with the charity Age Uk with whom we have a joint Knowledge Exchange programme.

Our research, coupled with our knowledge exchange strategy, will enable older people to understand what happens to cognitive abilities with increasing age, learn which potentially preventable factors affect brain health and cognitive function, benefit from more accurate diagnosis of Alzheimer's disease or delirium, and, for example, from information about ways to compensate for some of the effects of dementia by not undertaking certain forms of dual tasking. Our research will also benefit those who care for people with dementia; for instance, advice about the difficulties such patients have with carrying out more than one mental task simultaneously.

As regards public health providers, our research has the potential to lead to interventions to ameliorate age-related cognitive decline and provide clinical benefits through the development of methods for more accurate diagnosis of dementia or delirium. For third sector organisations, our research will provide benefits in terms of the advice and support they can offer to older people who are concerned about cognitive ageing and brain health. We have already provided this to Age UK for its widely-distributed book on Ageing Well.

CCACE members and core staff have a strong track record of engagement with policy makers. Our research will provide benefits to policy audiences at a national (UK and Scottish) government level and also NHS and local councils. This has and will continue to be in the form of research evidence about the effects of cognitive ageing, the importance of maintaining brain health, the life-long nature of ageing, earlier and accurate diagnosis of dementia (or otherwise), and ways in which cognitive decline might be ameliorated or delayed-all of crucial importance at a time of rapid population ageing. The commercial sector will benefit from our research because it involves the development of diagnostic tools as well as, for instance, guidelines for the care of individuals by private care organisations. All these beneficiaries are likely to benefit from our research within 1 to 5 years.

Our work with artists has benefited both that community and also the people who have come to see the science-art projects we have engaged in. Artist Linda Fleming produced an exhibition (shown at InSpace in Edinburgh and Hancock Gallery in Newcastle) that explored the association between cognitive and bodily health in the Lothian Birth Cohort 1936. We currently have renowned portrait artist Fionna Carlisle creating portraits of scientists and participants in our ageing cohorts to explore ageing. We have writer Ann Lingard creating life narratives of the scientists and participants of our Lothian Birth Cohorts. We have hosted and created three theatre productions to explore cognitive ageing. We have two grant applications in for more science-art projects. We plan more high-quality artistic joint projects to achieve awareness of our research issues.

For staff and research students working in the Centre, we ensure that they have multidisciplinary training. This makes them especially well prepared for an independent research career. They benefit from working in an area of such growing public importance, and in a Centre which works hard to create the best and widest awareness and understanding of our research.

Organisations

Publications

10 25 50
 
Title Brain Box 
Description Brain Box is a portable workshop/festival resource to excite children and adults about the brain, how it works and the changes it goes through in a lifetime. It is a resource for guided workshops, festivals, exhibitions and events that would over time develop an online "personality" tweeting about its day with photo's, comments and quotes: see me on Twitter @brainboxone 
Type Of Art Artefact (including digital) 
Year Produced 2014 
Impact To date, the Brain Box has received funding from the MRC Regional Communications Fund and, despite still being at the development stage, is planned to appear at workshops as part of the Edinburgh International Science Festival 14-18 April 2015. 
URL http://www.twitter.com/brainboxone
 
Title Brain Training on Trial 
Description An hour-long show developed for the Edinburgh Festival Fringe 2014, involving audience participation and presentation of research on the usefulness of brain training. The show took the form of a 'trial' in which the audience was the jury and co-presenter the judge. 
Type Of Art Performance (Music, Dance, Drama, etc) 
Year Produced 2014 
Impact The trailer for the show was uploaded to You Tube and has been viewed 534 times as at 7th November 2014 (http://www.youtube.com/watch?feature=player_embedded&v=9g2puKGaE-E). The post-event summing up video has also been uploaded to You Tube on 20th October 2014 and has been viewed 70 times (http://www.youtube.com/watch?v=fROGW49Z81Q). A blog post was also written summarising the evidence for and against brain training. 
URL http://researchtheheadlines.org/2014/09/09/brain-training-on-trial/
 
Title Fashion design final year show - Russ 
Description This CCACE member met with a fourth year student at Heriot Watt University studying Fashion Design who chose to base her final collection design concept around dementia. They discussed the science of dementia and its investigation. She subsequently developed the designs into scarves which she sold in aid of Alzheimer Scotland. 
Type Of Art Artefact (including digital) 
Year Produced 2016 
Impact The design student developed the designs into scarves which she sold in aid of Alzheimer Scotland. She is now developing the designs for a range with the high street retailer H&M. 
URL https://www.nadiapinkney.com/remember-me-knot
 
Title LBC1936 Fast Facts Card 
Description Dr Simon Cox and Professor Ian Deary designed a 'Lothian Birth Cohort 1936 Fast Facts Card' - a 12 facet credit-card sized concertina leaflet containing information about the LBC1936 study for distribution to the general public at future KE events, interested academics / potential collaborators, LBC members etc. 
Type Of Art Artefact (including digital) 
Year Produced 2014 
Impact This has been distributed to interested academics and potential collaborators and will be distributed to participants in the Lothian Birth Cohort 1936. Age Scotland have requested 150 and an initial print run consisted of 2000 copies. 
 
Title Lifetimes book - Ann Lingard 
Description CCACE collaborated with a local author, Ann Lingard, to create a short book entitled 'Lifetimes - personal stories from the Lothian Birth Cohorts'. Ann interviewed several participants in both Lothian Birth Cohorts 1921 and 1936 and several members of staff, including the Centre director, creating this short collection of life stories. It has been professionally typeset with an attractive cover and introduction by CCACE/LBC director Ian Deary. It is heavily illustrated with photographs reflecting the life courses of the participants and scientists in the Lothian Birth Cohort studies. 
Type Of Art Creative Writing 
Year Produced 2014 
Impact The book has been sent to all CCACE collaborators and contacts, as well as being given out to participants at the Lothian Birth Cohort reunion in April 2014. It has been available to download as an e-book on various websites for many months. About 2000 physical copies of the book have been printed. It is free on iTunes, and there is a nominal cost (77p) on Amazon for a Kindle edition. 
URL https://itunes.apple.com/gb/book/lifetimes/id893954634?mt=11
 
Title Portraits - Fionna Carlisle 
Description CCACE has been collaborating with a local artist, Fionna Carlisle, who has painted portraits of the Centre director, Ian Deary, several of the Centre's staff, and a number of participants from the Lothian Birth Cohort studies. She is aiming to complete a collection of over 20 portraits of participants and scientists. 
Type Of Art Artwork 
Year Produced 2014 
Impact The artwork has been displayed at a number of prestigious local and national events, including as part of an exhibition at the British Library in London entitled Portraying Ageing on 28th April 2014, and at local events associated with the MRC Centenary. The CCACE knowledge exchange officer and Fionna Carlisle, along with Centre director Ian Deary, are in discussion with local art galleries and museums with regard to a full-scale exhibition of these portraits and the scientific programme of work which lies behind them. 
URL http://www.fionnacarlisle.com/
 
Title The Art of Intelligent Ageing exhibition 
Description In 2012, artist Fionna Carlisle, began work on a series of portraits of Lothian Birth Cohorts participants and research team members. In October 2018, The Art of Intelligent Ageing exhibition showcased the completed series and featured interesting artifacts from the Lothian Birth Cohorts. 
Type Of Art Artistic/Creative Exhibition 
Year Produced 2018 
Impact 599 people attended the exhibition and it was covered by various media outlets including STV evening news and the Scotsman. 
URL https://www.scotsman.com/lifestyle/culture/art/art-reviews-the-art-of-intelligent-ageing-andrew-cran...
 
Title The Great British Brain Off - Alan Gow 
Description The Great British Brain Off. Show at the Edinburgh Festival Fringe as part of Edinburgh Beltane's Cabaret of Dangerous Ideas, Edinburgh, UK, 27th August 2015. Performance, associated trailer, and follow-up video: https://www.youtube.com/watch?v=X20p9oCYI8Y https://www.youtube.com/watch?v=yZF76K1hKDk 
Type Of Art Performance (Music, Dance, Drama, etc) 
Year Produced 2015 
Impact Raise the profile of cognitive ageing research. 
 
Title The Living Brain short film - Anne Milne 
Description CCACE collaborated with film maker Anne Milne to produce a short film describing the Lothian Birth Cohort 1921 and 1936 studies and charting the life course and current circumstances of one participant from each study. The film was premiered at the Lothian Birth Cohort reunion in April 2014 and has since been screened a number of times, including at the CCACE Annual Research Day in August 2014 and Midlothian Science Festival in October 2014. 
Type Of Art Film/Video/Animation 
Year Produced 2014 
Impact The film has been screened a number of times, both to research participants, collaborators and other academics, and members of the public attending a science festival talk. It has now been seen by, we estimate, many hundreds of people and Anne Milne has plans to submit it to film festivals and science festivals. The film is listed on www.imdb.com. 
URL http://www.imdb.com/name/nm3596775/
 
Description ALLEA UK representative - Pickersgill
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
URL http://www.allea.org/Pages/ALL/4/731.bGFuZz1FTkc.html
 
Description Age UK/AARP Global Council on Brain Health expert meeting (Gow)
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact The Global Council on Brain Health convenes experts who then produce reports on factors affecting cognitive and brain function. These are widely distributed so that people's knowledge and actions (e.g. lifestyle changes) are based upon the best available empirical evidence. This is done in part via Age UK, the largest UK ageing charity with a very wide reach to older people in the UK and internationally.
URL http://www.ageuk.org.uk/professional-resources-home/research/about-age-uk-research/the-global-counci...
 
Description Assigned Chair of SIGN Guidelines Committee on delirium - MacLullich
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
URL http://www.sign.ac.uk/pdf/Delirium_KQs_v0%203_consultation.pdf
 
Description BBSRC Bioscience for Society Strategy Panel - Pickersgill
Geographic Reach National 
Policy Influence Type Participation in advisory committee
 
Description Citizens Jury report on Guthrie spots - David Porteous
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description European Commission, Directorate General Education and Culture, Thematic Panel on Languages & Literacy
Geographic Reach Europe 
Policy Influence Type Participation in a advisory committee
Impact Informed the Government on educational changes.
 
Description Forum "Influencing the trajectories of ageing" - Ian Deary
Geographic Reach National 
Policy Influence Type Participation in a national consultation
Impact The Academy of Medical Science brought together international experts on the influences on human and other animal ageing systems. These were presented in a forum conducted under Chatham House rules. There was an invited audience of about 60 experts in total. Each of the presentations-including Ian Deary's-was summarised and compiled in a report that was made available as an online PDF, communicated to the news media, and is intended to influence policy makers on the important issue of how to optimise the trajectories of human health across the full life course.
URL https://acmedsci.ac.uk/more/news/trajectories-of-ageing-balancing-longevity-and-health
 
Description Global Council on Brain Health - Alan Gow
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Global Council on Brain Health (2017). "The Brain and Social Connectedness: GCBH Recommendations on Social Engagement and Brain Health."
URL http://www.GlobalCouncilOnBrainHealth.org
 
Description Global young leader in dementia - Russ
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact I was recommended by the MRC and selected as one of Europe's young leaders in dementia by the World Dementia Council. I attended the European event in London to identify innovative ideas to address dementia following the G8 Summit & World Council on Dementia. The priorities for dementia research and care which the global young leaders drafted at a number of international meetings were presented to the World Council on Dementia in 2015.
URL http://www.neurodegenerationresearch.eu/2015/03/young-leaders-from-across-europe-join-global-search-...
 
Description Government Office for Science "Evidence and Options for Preserving Cognition Through Life" - Ian Deary
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
URL http://www.ccace.ed.ac.uk/node/336
 
Description Influencing national health indicator - Russ
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
Impact My work on psychological distress (e.g. Russ et al., 2012) has been used to recommend the introduction of a new indicator by the Department of Health: "Excess under 75 mortality rate in adults with common mental illness" (Indicator 1.5 ii in the NHS Outcomes Framework 2015/16).
URL http://www.gov.uk/government/publications/nhs-outcomes-framework-2015-to-2016
 
Description MRC review of UK population studies - LBC
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL http://www.mrc.ac.uk/news-events/publications/maximising-the-value-of-uk-population-cohorts/
 
Description Northern Ireland Department for Communities, Irish Language Academy, Belfast
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Participation in a advisory committee
Impact Informed the public of educational changes.
 
Description Report for the Federation of European Academies of Medicine (FEAM) and All European Academies of Science (ALLEA) - David Hill
Geographic Reach Europe 
Policy Influence Type Participation in a national consultation
URL https://www.allea.org/wp-content/uploads/2018/11/Health_Inequalities_Symposium_Report.pdf.
 
Description Review of cognitive ageing and financial services
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL https://www.fca.org.uk/publication/research/ageing-mind-literature.pdf
 
Description SAPEA report "Transforming the Future of Ageing" - Alan Gow
Geographic Reach Europe 
Policy Influence Type Participation in a advisory committee
URL https://ec.europa.eu/research/sam/index.cfm?pg=ageing
 
Description Science and Trust Parliamentary Links Day - Pickersgill
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
 
Description Scottish Government Data Linkage Framework - Deary
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
 
Description Scottish Public Health Network (Johnson)
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description ADRC - Scotland, ESRC
Amount £7,930,752 (GBP)
Funding ID ES/L007487/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 11/2013 
End 10/2018
 
Description AHRC-OWRI Multilingualism: Empowering Individuals, Transforming Societies (MEITS)
Amount £419,496 (GBP)
Funding ID AH/N004671/1 
Organisation Arts & Humanities Research Council (AHRC) 
Sector Public
Country United Kingdom
Start 07/2016 
End 06/2020
 
Description Advancing Care and treatment of Vascular Dementia (Stroke Association/BHF/Alzheimer's Society)
Amount £800,000 (GBP)
Organisation Stroke Association 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Age UK - The Disconnected Mind, Phase 3
Amount £1,317,193 (GBP)
Organisation Age UK 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2016 
End 03/2019
 
Description Alzheimer Scotland Dementia Reseach Centre renewal funding (CCACE sister Centre) - John Starr
Amount £750,000 (GBP)
Organisation Alzheimer Scotland 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Alzheimer Scotland: Marjorie MacBeath bequest - Russ
Amount £100,000 (GBP)
Funding ID R44120 
Organisation Alzheimer Scotland 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2015 
End 08/2016
 
Description Alzheimer's Research UK Major Project Grant
Amount £166,833 (GBP)
Funding ID ARUK-PG2017B-10 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2017 
End 09/2020
 
Description Alzheimer's Research UK senior research fellowship
Amount £420,000 (GBP)
Funding ID ARUK-SRF2018B-009 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2019 
End 06/2023
 
Description Alzheimer's Society - Fergus Doubal
Amount £245,385 (GBP)
Organisation Alzheimer’s Society 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2015 
End 09/2017
 
Description Brain imaging and cognitive ageing in the Lothian Birth Cohort 1936: IV
Amount £596,355 (GBP)
Funding ID MR/R024065/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 05/2018 
End 04/2021
 
Description British Academy - Alan Gow
Amount £14,939 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 03/2015 
End 03/2016
 
Description CSO Cerebrovascular reactivity - Wardlaw Doubal Marshall
Amount £137,420 (GBP)
Organisation Chief Scientist Office 
Sector Public
Country United Kingdom
Start 02/2014 
End 07/2015
 
Description Chest Heart Stroke Scotland - Wardlaw
Amount £75,815 (GBP)
Organisation Chest Heart & Stroke Scotland 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2014 
End 01/2016
 
Description Clinical Fellowship - Russ
Amount £100,000 (GBP)
Funding ID R44120 
Organisation Alzheimer Scotland 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2015 
End 08/2016
 
Description Colciencias, Colombia. Emergent Social and Health Challenges
Amount £16,000 (GBP)
Organisation Administrative Department of Science, Technology and Innovation (Colciencias) 
Sector Public
Country Colombia
Start 07/2016 
End 12/2016
 
Description Conference travel funding - Alan Gow
Amount £950 (GBP)
Organisation Royal Society of Edinburgh (RSE) 
Sector Learned Society
Country United Kingdom
Start 04/2016 
End 04/2016
 
Description Confidence in Global Mental Health Research 2017
Amount £188,567 (GBP)
Funding ID MR/R01910X/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2018 
End 02/2019
 
Description Doctoral Training Programme - Karen Horsburgh
Amount £346,000 (GBP)
Organisation Alzheimer’s Society 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2015 
End 08/2018
 
Description Dunhill Medical Trust - Alan Gow
Amount £74,700 (GBP)
Funding ID R359/0514 
Organisation The Dunhill Medical Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2014 
End 05/2016
 
Description Dunhill Medical Trust - Tablet for Healthy Ageing (Gow)
Amount £74,700 (GBP)
Funding ID R359/0514 
Organisation The Dunhill Medical Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2014 
End 04/2016
 
Description EPSRC Multi-modal retinal biomarkers - Wardlaw Doubal Deary
Amount £1,100,000 (GBP)
Funding ID EP/M005976/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start 04/2015 
End 03/2018
 
Description EPSRC: retinal biomarkers
Amount £1,153,990 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start 02/2015 
End 01/2018
 
Description ESRC Project Grant - Working memory across the adult lifespan: An adversarial collaboration (Logie)
Amount £1,154,370 (GBP)
Funding ID ES/N010728/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 05/2016 
End 04/2020
 
Description ESRC: Epigenetics
Amount £667,456 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2015 
End 09/2018
 
Description EU Joint Programme - neurodegeneration (Wardlaw)
Amount € 47,416 (EUR)
Organisation EU Joint Programme - Neurodegenerative Disease Research (JPND) 
Sector Public
Country European Union (EU)
Start 10/2014 
End 03/2015
 
Description Edinburgh Lothians Health Foundation BraINS - Shenkin Wardlaw Job
Amount £38,810 (GBP)
Organisation Edinburgh & Lothians Health Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2014 
End 03/2015
 
Description Evaluating Longitudinal Changes in the Human Structural Connectome in Relation to Cognitive Aging
Amount $502,543 (USD)
Funding ID 1R01AG054628-01A1 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2017 
End 04/2022
 
Description FAPESP-HWU Scheme 2016 (Brazil - Heriot-Watt University)
Amount £40,000 (GBP)
Organisation São Paulo Research Foundation (FAPESP) 
Sector Public
Country Brazil
Start 08/2016 
End 08/2018
 
Description Gow Hagger-Johnson - Research visitors to Scotland
Amount £300 (GBP)
Organisation Royal Society of Edinburgh (RSE) 
Sector Learned Society
Country United Kingdom
Start 04/2014 
End 05/2014
 
Description Guest Professor programme - Alan Gow
Amount £3,325 (GBP)
Organisation University of Copenhagen 
Sector Academic/University
Country Denmark
Start 11/2015 
End 12/2015
 
Description Guest professor - Alan Gow 2013
Amount £22,500 (GBP)
Organisation Nordea Foundation 
Sector Charity/Non Profit
Country Denmark
Start 05/2013 
End 07/2013
 
Description Guest professor - Alan Gow 2014
Amount £20,000 (GBP)
Organisation Nordea Foundation 
Sector Charity/Non Profit
Country Denmark
Start 11/2014 
End 12/2014
 
Description Harris pilot study award - Generation Scotland
Amount £8,800 (GBP)
Organisation University of Edinburgh 
Department MRC Centre for Cognitive Ageing and Cognitive Epidemiology
Sector Public
Country United Kingdom
Start 04/2014 
End 06/2014
 
Description Heriot-Watt Principal's Public Engagement Award (Gow)
Amount £1,000 (GBP)
Organisation Heriot-Watt University 
Sector Academic/University
Country United Kingdom
Start 06/2016 
End 06/2016
 
Description How do peripheral and central vascular markers relate to cognitive decline? - Deary
Amount £91,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 07/2015 
End 01/2017
 
Description INTERpreting epigenetic signatires in Studies of Early Life Adversity (interSTELA) - Deary
Amount £199,512 (GBP)
Funding ID ES/N000382/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 09/2015 
End 08/2017
 
Description Junior Investigator Pilot Award - Zoe Tieges
Amount $49,871 (USD)
Organisation Nidus Partners LP 
Start 04/2018 
End 10/2018
 
Description LACunar Intervention Trial - Fergus Doubal
Amount £847,771 (GBP)
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2016 
End 02/2019
 
Description Leverhulme Trust Research Grant
Amount £106,031 (GBP)
Funding ID RPG-2013-066 
Organisation The Leverhulme Trust 
Sector Academic/University
Country United Kingdom
Start 11/2013 
End 10/2015
 
Description MRC Confidence in Global Mental Health Research Grant
Amount £196,755 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2018 
End 12/2019
 
Description MRC DTP Precision Medicine PhD - Susan Shenkin
Amount £86,780 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC Integrated dementia research environment
Amount £6,825,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2015 
End 03/2016
 
Description MRC Mental Health Data Pathfinder award - Andrew McIntosh, Matthew Iveson
Amount £1,200,000 (GBP)
Funding ID MC_PC_17209 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2018 
End 03/2020
 
Description MRC UK Dementia Platform
Amount £5,639,037 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2014 
End 03/2019
 
Description MRC travel grant - Kathryn Walesby
Amount £1,800 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description MRC: LBC1936 III
Amount £1,316,451 (GBP)
Funding ID MR/M013111/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2015 
End 02/2019
 
Description Moray Endowment Fund (Pickersgill) - animal models and dynamics of biomedicine
Amount £963 (GBP)
Organisation University of Edinburgh 
Department Moray Endowment Fund
Sector Academic/University
Country United Kingdom
Start 01/2013 
End 12/2013
 
Description NIA - Human structural connectome
Amount $2,384,683 (USD)
Funding ID R01AG054628 
Organisation National Institute on Aging 
Sector Public
Country United States
Start 07/2017 
End 06/2022
 
Description Nioi et al Blue light exposure and sleep
Amount £8,164 (GBP)
Organisation Government of Scotland 
Sector Public
Country United Kingdom
Start 01/2014 
End 12/2014
 
Description PhD studentship - Horsburgh
Amount £85,000 (GBP)
Organisation Alzheimer’s Society 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2016 
End 08/2019
 
Description PhD studentship - Karen Horsburgh
Amount £99,228 (GBP)
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2015 
End 08/2018
 
Description Pickersgill - visiting scholar, Wisconsin-Madison
Amount £932 (GBP)
Organisation Royal Society of Edinburgh (RSE) 
Sector Learned Society
Country United Kingdom
Start 03/2014 
End 04/2014
 
Description Postdoctoral Fellowship
Amount £148,126 (GBP)
Funding ID 316 
Organisation Alzheimer’s Society 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2017 
End 03/2020
 
Description Project grant - Horsburgh
Amount £326,594 (GBP)
Organisation Alzheimer’s Society 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Project grant - Horsburgh
Amount £561,607 (GBP)
Funding ID ARUK-PG2016B-6 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Project grant - JPND (Deary)
Amount £592,325 (GBP)
Funding ID MR/N027558/1 
Organisation Medical Research Council (MRC) 
Department MRC Human Nutrition Research Unit
Sector Public
Country United Kingdom
Start 05/2016 
End 04/2019
 
Description Project grant - MacLullich
Amount £185,751 (GBP)
Funding ID R484/0516 
Organisation The Dunhill Medical Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2017 
End 01/2020
 
Description Project grant - MacLullich
Amount £260,000 (GBP)
Funding ID ARUK-PG2016B-12 
Organisation Alzheimer's Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2016 
End 10/2018
 
Description Project grant - The Intervention Factory (Gow)
Amount £343,728 (GBP)
Organisation Velux Foundations 
Sector Charity/Non Profit
Country Denmark
Start 07/2016 
End 06/2019
 
Description Research and Development Grant Scheme (Harrison)
Amount £25,000 (GBP)
Funding ID Ref 854 
Organisation Edinburgh & Lothians Health Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2016 
End 12/2017
 
Description Researcher Links, British Council - Aribisala / Gow
Amount £4,320 (GBP)
Organisation British Council 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2014 
End 10/2014
 
Description Rewrite the Headlines: Follow-up funding (Gow)
Amount £5,000 (GBP)
Organisation The British Academy 
Sector Academic/University
Country United Kingdom
Start 04/2016 
End 03/2017
 
Description SFC SINAPSE Network development - Wardlaw et al
Amount £325,000 (GBP)
Organisation Government of Scotland 
Department Scottish Funding Council
Sector Public
Country United Kingdom
Start 10/2014 
End 09/2019
 
Description Scottish Government - Alan Gow
Amount £8,164 (GBP)
Organisation Government of Scotland 
Sector Public
Country United Kingdom
Start 01/2014 
End 03/2017
 
Description Seniors USP - LLHW
Amount £992,001 (GBP)
Organisation Medical Research Council (MRC) 
Department Lifelong Health and Wellbeing (LLHW)
Sector Public
Country United Kingdom
Start 05/2014 
End 04/2017
 
Description Starter grant for clinical lecturers - Russ
Amount £30,000 (GBP)
Funding ID AMS-SGCL12-Russ 
Organisation Academy of Medical Sciences (AMS) 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2015 
End 08/2016
 
Description Starter grant for clinical lecturers - Russ
Amount £30,000 (GBP)
Funding ID AMS-SGCL12-Russ 
Organisation Academy of Medical Sciences (AMS) 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2015 
End 08/2016
 
Description Strathclyde University PhD Studentship Research Excellence Award for Health (Gow)
Amount £58,060 (GBP)
Organisation University of Strathclyde 
Sector Academic/University
Country United Kingdom
Start 09/2017 
End 08/2020
 
Description Stroke Association - Fergus Doubal
Amount £234,989 (GBP)
Funding ID TSA15LECT04 
Organisation Stroke Association 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2015 
End 05/2020
 
Description The Disconnected Mind: Phase 4
Amount £1,058,650 (GBP)
Organisation Age UK 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2019 
End 03/2022
 
Description The Intervention Factory: PhD Studentship - Alan Gow
Amount £63,396 (GBP)
Organisation Velux Foundations 
Sector Charity/Non Profit
Country Denmark
Start 09/2017 
End 08/2020
 
Description Translational Neuroscience program - Anna Stevenson
Amount £119,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Translational Neuroscience program - Robert Hillary
Amount £119,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Travel award - Russ
Amount £1,000 (GBP)
Organisation Alzheimer Scotland 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2016 
End 08/2016
 
Description Travel award - Russ
Amount £5,405 (GBP)
Organisation Scottish Universities Life Sciences Alliance 
Sector Academic/University
Country United Kingdom
Start 06/2016 
End 08/2016
 
Description Travel award - Tieges
Amount £800 (GBP)
Organisation Guarantors of Brain 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2016 
End 06/2016
 
Description Travel grant - Russ
Amount £5,405 (GBP)
Organisation Scottish Universities Life Sciences Alliance 
Sector Academic/University
Country United Kingdom
Start 06/2016 
End 08/2016
 
Description U01 Research Grant
Amount $155,358 (USD)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start  
 
Description UofE Sparking Impact scheme - Shenkin Wardlaw
Amount £19,417 (GBP)
Organisation University of Edinburgh 
Sector Academic/University
Country United Kingdom
Start 03/2014 
End 08/2014
 
Description WT: MRI
Amount £600,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2015 
End 12/2019
 
Description WT: Stratifying depression
Amount £4,591,695 (GBP)
Funding ID 104036/Z/14/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2015 
End 12/2020
 
Description Wellcome Trust MRI lifecourse influences - Wardlaw
Amount £600,000 (GBP)
Funding ID 106824/Z/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2015 
End 12/2019
 
Description Wellcome Trust Multiuser Equipment Grant - Megan Holmes
Amount £1,000,000 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Wellcome Trust STRADL award
Amount £4,750,000 (GBP)
Funding ID 104036/Z/14/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2015 
End 12/2019
 
Description Wellcome Trust Society and Ethics Small Grant
Amount £3,500 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2014 
End 06/2015
 
Title 3D brain 
Description A 3D Brain based on MRI Scans has been developed. This Brain is true 3D in cyberspace and can be viewed and projected in anaglyph 3D and well as a higher quality rendition using a fast shuttered glasses system from Nvidia. Two Brains are available for viewing at the moment , a healthy young and a healthy old brain. The 3D brain can be rotated and zoomed in real time to allow the demonstration of anatomical features on the reconstructed models. The tools developed are capable of importing any 3D model and future developments may include tractography etc. 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2013 
Provided To Others? Yes  
Impact This system was used as a demonstrator at the opening of CRIC by HRH Duke of Edinburgh. In 2011 it was demonstrated at the Edinburgh International Science Festival that attracted ~3000 visitors, at the Glasgow Science Centre, and has been taken around schools by CCACE employee Jack Nissan. In 2014 the 3D brain was demonstrated at the Edinburgh Neuroscience Day (March 12th 2014) and at a reception held by Age UK at St James's Palace and hosted by HRH Prince Charles (Jan 28th 2014). 
 
Title CCACE - LBC Lifetimes website 
Description The professional writer Ann Lingard composed stories of the lives of members of the Lothian Birth Cohorts of 1921 and 1936 and some of the wscientists working on the research. Each life was "told" as a small online facsimilie book with pictures across the lifecourse of each person. The individual books are professional looking and they have been gathered on to a website. The CCACE Systems Analyst worked closely with the CCACE Knowledge Exchange Officer to develop a new website for a large CCACE arts project called LBC Lifetimes. The project was set up to create stories of the lives and lifetimes of some of the participants and scientists involved in the LBC1936 study. The site has been viewed over 2300 times. 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact The stories are available internationally for those wishing to learn more about the personal backgrounds of participants and esearchers in the Lothian Birth Cohort studies. 
URL http://www.lbclifetimes.org
 
Title Cognitive Estimation Task - MacPherson 
Description This is a cognitive test used in the detection of dementia and cognitive ability. 
Type Of Material Physiological assessment or outcome measure 
Year Produced 2015 
Provided To Others? Yes  
Impact Provided to the Psychology Research Laboratory, IRCCS Istituto Auxologico Italiano, Ospedale San Giuseppe, Piancavallo, Italy and an Italian version of the Cognitive Estimation task was devised (Scarpina et al., 2015; Neurological Sciences) 
URL https://www.era.lib.ed.ac.uk/handle/1842/8747
 
Title Cox - frontal lobe parcellation method 
Description Identified and developed a novel method for identifying frontal lobe sub-regions from gyral topography based on a synthesis of previous methods and data from cytoarchitecture and hodology. 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2014 
Provided To Others? Yes  
Impact The method was published in Brain Structure and Function (Impact Factor: 7.84) and this paper has been made available with supporting documentation online in the Image Analysis Tool section of the Brain Imaging Research Centre website (http://www.bric.ed.ac.uk/research/imageanalysis.html). Other publications resulted from this method and are published Cortex and Intelligence. 
 
Title Developing a non-invasive cognitive aid to diagnosis and follow up of Alzheimer's Disease - Robert Logie 
Description Led by CCACE group leader, Professor Robert Logie and in collaboration with a number of CCACE members a new research tool for diagnosing Alzheimer's Disease has been developed. Over 20 years of laboratory based scientific research, development of prototype software and initial clinical trials has led to a successful collabortion with Toshiba to develop the tool. 
Type Of Material Physiological assessment or outcome measure 
Provided To Others? No  
Impact Collaboration commenced in October 2010. Planned output will be a proven prototype diagnostic aid that may be used in Primary Care and also for evaluation of the effectiveness of interventions in clinical trials. Interest expressed for inclusion in clinical trials of pharmaceutical interventions due to run in 2011. In 2012 the test was adopted by the NHS Medical Devices Unit for Greater Glasgow and Clyde to develop from the current research versions into versions that can be used in routine clinical settings by nurses and General Practitioners. Scottish Health Innovations Ltd. is currently collating the necessary documentation to apply for approval from the UK Medicines and Healthcare products Regulatory Agency for clinical use within the NHS and in healthcare across Europe. 
 
Title Genomic SEM - David Hill 
Description In collaboration with the University of Texas at Austin, and the Vrije Universiteit Amsterdam, David Hill was involved in a collaboration that resulted in the method of Genomic SEM being published in Nature Human Behaviour. This tool allows one to jointly analyse the genetic contributions to multiple traits simultaneously. 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2018 
Provided To Others? Yes  
Impact N/A. The manuscript describing genomic SEM has been accepted for publication at Nature Human Behaviour and will be available for public use. 
URL https://github.com/MichelNivard/GenomicSEM
 
Title IST-3 trial thrombolysis 
Description Joanna Wardlaw has been involved in the third International Stroke Trial (IST-3), a randomised controlled trial of the benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 hours of acute ischaemic stroke. 
Type Of Material Model of mechanisms or symptoms - human 
Provided To Others? No  
Impact Thrombolysis is now widely used in >80's for treatment of acute stroke, thanks to IST-3. 
 
Title Image analysis method - hippocampal shape modelling 
Description In collaboration with the Korean Advanced Institute for Science and Technology, we have developed a novel method for hippocampal shape modelling. 
Type Of Material Physiological assessment or outcome measure 
Provided To Others? No  
Impact Cox SR*, Valdés Hernández MC*, Kim J, Royle NA, MacPherson SE, Ferguson KJ, Muñoz Maniega S, Anglaban D, Aribisala BS, Bastin ME, Park J, Starr JM, Deary IJ, MacLullich AJM, Wardlaw JM. Associations between hippocampal morphology, diffusion characteristics, and salivary cortisol in older men. Psychoneuroendocrinology, doi: 10.1016/j.psyneuen.2017.01.027. Kim J, Valdés Hernández MC, Royle NA, Park J. Hippocampal shape modelling based on a progressive template surface deformation and its verification. IEEE Trans Med Imaging 2015 Jun;34(6):1242-61 Valdés Hernández MC, Cox SR, Kim J, Royle NA, Muñoz Maniega S, Gow AJ, Anglaban D, Bastin ME, Park J, Starr JM, Wardlaw JM, Deary IJ. Hippocampal morphology and cognitive functions in community-dwelling older people: the Lothian Birth Cohort 1936. Neurobiol Aging in press. 
URL http://ieeexplore.ieee.org/document/6990617/?reload=true
 
Title Image analysis methods - IXICO 
Description Wardlaw and colleagues have been involved in developing analysis method for older subjects with IXICO, a commercial imaging research group. 
Type Of Material Physiological assessment or outcome measure 
Provided To Others? No  
Impact A Technology Strategy Board grant has been applied for based on pilot work. 
 
Title Liewald - CCACE cluster 
Description The CCACE computer cluster has been designed to allow it to deal with large GWAS datasets held by CCACE such as 1000G, exome sequencing and also the Generation Scotland reference genome sets. In conjunction with this are new file handling and merging techniques and pipelines which had to be developed to allow researchers to access and utilise these huge data resources. 
Type Of Material Biological samples 
Provided To Others? No  
Impact We have the capability of conducting, securely, large scale genetic analyses for our team and of allowing access to collaborators internationally. 
 
Title New method of perivascular space segmentation on brain MRI 
Description MRC-funded imaging team on the LBC1936 developed a new method of perivascular space segmentation, which shows good concordance with neuroradiological assessments. 
Type Of Material Physiological assessment or outcome measure 
Year Produced 2016 
Provided To Others? Yes  
Impact Ballerini L, Lovreglio R, Valdés Hernández MC, Gonzalez-Castro V, Muñoz Maniega S, Pellegrini E, Bastin ME, Deary IJ, Wardlaw JM. Application of the ordered logit model to optimising Frangi filter parameters for segmentation of perivascular spaces. Procedia Comp Sci 2016 90:61-67. 
URL http://www.sciencedirect.com/science/article/pii/S1877050916311899
 
Title Observational Scale of Level of Alertness (OSLA) - Roanna Hall 
Description CCACE member Dr Roanna Hall developed a new assessment tool for level of alertness in delirium, named the Observational Scale of Level of Alertness (OSLA). It is in the early stages of development, and an abstract assessing its usefulness in assessing alertness in delirium in patients with acute hip fracture was accepted for poster presentation at the European Delirium Association conference in Amsterdam, 11-12 November 2010. A poster on the OSLA was presented at the American Delirium Society inaugural conference in Indianapolis in June 2011 
Type Of Material Physiological assessment or outcome measure 
Provided To Others? No  
Impact The tool has gained interest from members of conferences, and it has been taken forward for further development. In 2011, Dr Hall and colleagues have been working towards validating and publishing the OSLA. This research tool assesses alertness in hospital inpatients. It fills a gap in the current literature and complements our new cognitive assessment (Edinburgh Delirium Test Boxes 1 and 2). The OSLA has been used several hundred times in our research studies and is being refined with the help of CCACE statistician Dr Mike Allerhand. The refined version of the OSLA is due to be used in new studies in Oslo and Ireland. 
 
Title fastBAT - Hill 
Description As part of a collaboration with the University of Queensland we have developed a method, called fastBAT, for combining single nucleotide polymorphism data into a single statistic representing a gene or a group of genes. This allows us to examine the joint effect of multiple genetic variants which can be used as a biomarker for ageing and ageing phenotypes. 
Type Of Material Improvements to research infrastructure 
Year Produced 2015 
Provided To Others? Yes  
Impact Allow data quicker anlaysis. 
URL http://cnsgenomics.com/software/gcta/fastBAT.html
 
Title Brain Images of Normal Subjects (BRAINS) Imagebank 
Description The Brain Images of Normal Subjects (BRAINS) imagebank is an integrated repository project sponsored by the University of Edinburgh and the Scottish Imaging Network: A Platform for Scientific Excellence (SINAPSE) collaborators. The purpose of BRAINS is to provide sharing and archiving of detailed normal human brain imaging and relevant phenotypic data, to create better estimates of the range of normal brain size and integrity across the life-course. The Lothian Birth Cohort 1921 and 1936 brain imaging data along with limited clinical data has been added to this resource. BRAINS is a living imagebank where new data will be added when available. Initially BRAINS will contain existing data from n=763 healthy volunteer subjects, range neonatal and 19-81 years of age, from projects in 3 centres. A further n=2119 subjects aged from prenatal to 90 years old with existing records from 15 other projects in Scotland are currently being collected, collated and quality control (QC) checked. Additional completed and ongoing studies of normal individuals will be uploaded as they become available. The data include several magnetic resonance imaging (MRI) sequences, including T1, T2, T2*, fluid attenuated inversion recovery (FLAIR), and Diffusion Tensor Imaging (DTI), in DICOM and NIfTI format, and a wide range of linked metadata, such as age, history, physiological measures (e.g. blood pressure), cognitive ability, and perinatal information (neonatal data). Data access is governed by a steering committee comprising the PIs of the contributing studies, experts in ethics, law and governance, and lay representatives. Applications for data access can be made online, and will be granted by the steering committee subject to the completion of a formal Data Access Agreement. http://www.brainsimagebank.ac.uk/ 
Type Of Material Database/Collection of data 
Year Produced 2016 
Provided To Others? Yes  
Impact The initial publication which describes the resource was: "A brain imaging repository of normal structural MRI across the life course: Brain Images of Normal Subjects (BRAINS)" Dominic E Job, David A Dickie, David Rodriguez, Andrew Robson, Cyril Pernet, Mark Bastin, James P Boardman, Alison D Murray, Trevor Ahearn, Gordon D Waiter, Roger T Staff, Ian J Deary, Susan D Shenkin, Joanna M Wardlaw. NeuroImage. doi: 10.1016/j.neuroimage.2016.01.027 PMID: 26794641. We have developed seven age-specific atlases of T1 brain MRI from 25 to 92 years, which have been made available on the BRAINS website. Dickie, David Alexander; Job, Dominic E.; Rodriguez, David; Robson, Andrew; Danso, Samuel; Pernet, Cyril; Bastin, Mark E.; Deary, Ian J.; Shenkin, Susan D.; Wardlaw, Joanna M.. (2016). Brain Imaging of Normal Subjects (BRAINS) age-specific MRI atlases from young adults to the very elderly (v1.0), [dataset]. University of Edinburgh, Edinburgh Imaging, CCBS, BRAINS Imagebank. http://dx.doi.org/10.7488/ds/1369. 
URL http://www.brainsimagebank.ac.uk
 
Title Enhancing the Scottish Mental Survey 1947 - Matthew Iveson 
Description Dr Iveson is involved in developing the Scottish Mental Survey 1947 cohort, linking existing research data to historical administrative records (birth records from 1935-1937 available from Digitising Scotland), to current administrative records (Scottish Census 2001 and 2011) and to novel health records (Prescribing Information System). This is an extension of previous linkages, and improves the utility of the Scottish Mental Survey 1947 cohort as a research tool. The links are to be retained so that future researchers can request linked data for the cohort without the need to re-trace records from scratch. 
Type Of Material Database/Collection of data 
Year Produced 2019 
Provided To Others? Yes  
Impact The database is under development but will be available to other researchers in 2019 
 
Title Model sensitivity to missing data 
Description A new procedure of longitudinal model sensitivity analysis to missing data has been developed and is described in: Allerhand, M., Gale, C. R., Deary, I, J. (2014). The dynamic relationship between cognitive function and positive wellbeing in older people: a prospective study using the English Longitudinal Study of Ageing. Psychology and Aging. 29(2), 306-318. doi:10.1037/a0036551. 
Type Of Material Data handling & control 
Year Produced 2014 
Provided To Others? Yes  
Impact The procedure has been described in the following publication: Allerhand, M., Gale, C. R., Deary, I, J. (2014). The dynamic relationship between cognitive function and positive wellbeing in older people: a prospective study using the English Longitudinal Study of Ageing. Psychology and Aging. 29(2), 306-318. doi:10.1037/a0036551. 
 
Title Novel data analysis method - Mike Allerhand 
Description Novel data analysis method: Questionnaire item bias by continuous covariates. http://www.ccace.ed.ac.uk/research/allerhand 
Type Of Material Data analysis technique 
Year Produced 2017 
Provided To Others? Yes  
Impact Providing a statistical service. 
URL http://www.ccace.ed.ac.uk/research/allerhand
 
Description "Short-term memory binding: validity as a cognitive biomarker for Alzheimer's disease across cultures and nations" - funded by Alzheimer's Society 
Organisation Cayetano Heredia University
Country Peru 
Sector Academic/University 
PI Contribution We have provided the methodology to undertake this project. I have met Dr Nilton Custodio during the World Congress of Neurology, celebrated in Chile in 2015 and in the AAIC 2016 in Toronto. I have met the team via teleconferences during which we have been assembling the team that will support this study locally.
Collaborator Contribution The Peruvian Institute of Neuroscience runs a 3-year longitudinal study as part of the programme of the title. This involved assessing elderly people from Peru living in urban and rural areas and with different levels of education ad languages
Impact Data collection in progress. As part of the meeting held in Santiago in 2015 to which other experts of Latin American Country attended, including Prof. Ricardo Nitrini from Brazil, Prof. Francisco Lopera, from Colombia and Prof. Facundo Manes from Argenitina, we prepared a Policy Paper to raise awareness about challenges in Latin America countries. This paper is submitted for publication.
Start Year 2016
 
Description "Short-term memory binding: validity as a cognitive biomarker for Alzheimer's disease across cultures and nations" - funded by Alzheimer's Society 
Organisation Del Rosario University
Country Colombia 
Sector Academic/University 
PI Contribution We have provided the methodology to undertake this project. I have visited and trained at The Institute of Psychology, Universidad de Valle and have delivered talks to the professional community, undergraduate and postgraduate students. I have been involved in assembling the clinical and neuroimaging team that will support this study locally.
Collaborator Contribution The Institute of Psychology of the above University of is supporting a 3-year longitudinal study on MCI. This involves behavioural, EEG and MRI measures of cognitive decline in elderly people with MCI. In collaboration with the Foundation Valle del Lili, we have secured funding for a 3-year longitudinal study using fMRI to follow up patents with MCI.
Impact 1) Expanded the UK-Latin America Brain Connectivity Research Network (Heriot-Watt University - and HCN University of Edinburgh, UK - Cali, Colombia). 2) A new research agenda has been launched that comprises behavioural and neuroimaging study of MCI patients all funded by local institutions.
Start Year 2016
 
Description Air pollution exposure - Russ 
Organisation Karolinska Institute
Country Sweden 
Sector Academic/University 
PI Contribution Two projects are being undertaken with the Swedish team. 1. "Are epigenetic changes associated with air pollution exposure in the SATSA cohort?" 2016 - Karolinska Institutet, Sweden. Contributions: This work is at a preliminary stage but we are cleaning the data and hope to begin analysing them soon. 2. "Is air pollution associated with neuroimaging changes" - Karolinska Institutet, Sweden. Contributions: This work is at a preliminary stage but we are cleaning the data and hope to begin analysing them soon.
Collaborator Contribution Sharing Joint research expertise.
Impact No outcomes to date as the collaboration is very new.
Start Year 2016
 
Description Allerhand - BMI and cognitive ageing (2013) 
Organisation Karolinska Institute
Country Sweden 
Sector Academic/University 
PI Contribution The Centre's statistician is engaged in a collaborative research project on BMI and cognition.
Collaborator Contribution This is a collaborative research project. Previously, a researcher from Karolinska has visited the Centre.
Impact Publications are forthcoming.
Start Year 2013
 
Description Allerhand - BMI and cognitive ageing (2013) 
Organisation University of California, Riverside
Country United States 
Sector Academic/University 
PI Contribution The Centre's statistician is engaged in a collaborative research project on BMI and cognition.
Collaborator Contribution This is a collaborative research project. Previously, a researcher from Karolinska has visited the Centre.
Impact Publications are forthcoming.
Start Year 2013
 
Description Assessment of category fluency in ageing - MacPherson 
Organisation Korea Advanced Institute of Science and Technology (KAIST)
Department Computer Science Department
Country Korea, Republic of 
Sector Academic/University 
PI Contribution As a result of Challenge Investment funding, University of Edinburgh, my colleague Dr Maria Wolters and I made our first visit to our new collaborator, Professor Jong C. Park, School of Computing, KAIST, South Korea in February 2015. We have started examining traditional and acoustic data from semantic fluency, as well as, manual and semi-automated scoring methods for the task in both healthy and pathological aging. The School of Computing have devised the automated scoring methods and my contribution is the design and interpretation of our fluency work.
Collaborator Contribution As a result of Challenge Investment funding, University of Edinburgh, my colleague Dr Maria Wolters and I made our first visit to our new collaborator, Professor Jong C. Park, School of Computing, KAIST, South Korea in February 2015. We have started examining traditional and acoustic data from semantic fluency, as well as, manual and semi-automated scoring methods for the task in both healthy and pathological aging. The School of Computing have devised the automated scoring methods and my contribution is the design and interpretation of our fluency work.
Impact Papers published and others in preparation.
Start Year 2015
 
Description Biomarkers for dementia and cognitive ageing - Russ 
Organisation University of Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution I will analyse the data.
Collaborator Contribution Glasgow will analyse urinary proteomic samples .
Impact None as yet.
Start Year 2015
 
Description CCACE - Oregon Health and Sciences University (OHSU) 
Organisation Oregon Health and Science University
Department Layton Aging & Alzheimer's Disease Center
Country United States 
Sector Academic/University 
PI Contribution CCACE hosted a visit from the Oregon Health and Sciences University team of senior scientists (8 people) in September 2013. The aim was to develop more formal collaborations between the UK and USA in ageing research. The team spent 2 days with CCACE in various meet the staff meetings.
Collaborator Contribution The OHSU team have offered to host 3 members of CCACE on a return visit to Oregon in February 2014. Further correspondence has taken place between Dr Alex WEiss and Professor Jean Manson and the team at Oregon and planned collaborations are ongoing.
Impact There are plans to create formal collaborations between CCACE and OHSU scienitsts that will result after the reciprocal visit. This is intended to lead to joint publications between CCACE and OHSU.
Start Year 2013
 
Description Cognitive estimation in an Italian population - MacPherson 
Organisation Fondazione IRCCS Istituto Nazionale dei Tumori
Country Italy 
Sector Charity/Non Profit 
PI Contribution My collaborators translated into Italian the new versions of the Cognitive Estimation task (CET) devised by me (MacPherson et al., 2014, PLOS-One) and administered the tasks to the healthy population to examine the influence of age, gender and education on performance and providing Italian normative data. We are now examining whether non-demented Parkinson's disease patients are impaired on the CET and what underlies their impairments. My collaborators have assessed the participants, ran the statistical analyses and wrote drafts of the manuscripts. I have devised the tests, provided the theoretical input into the work and have also contributed to the writing of the manuscripts.
Collaborator Contribution My collaborators translated into Italian the new versions of the Cognitive Estimation task (CET) devised by me (MacPherson et al., 2014, PLOS-One) and administered the tasks to the healthy population to examine the influence of age, gender and education on performance and providing Italian normative data. We are now examining whether non-demented Parkinson's disease patients are impaired on the CET and what underlies their impairments. My collaborators have assessed the participants, ran the statistical analyses and wrote drafts of the manuscripts. I have devised the tests, provided the theoretical input into the work and have also contributed to the writing of the manuscripts.
Impact It has resulted in new versions of a test that is typically used in neuropsychological clinics in Italy.
Start Year 2015
 
Description Collaboration with the University of Texas at Austin and the Vrije Universiteit Amsterdam - David Hill 
Organisation Free University of Amsterdam
Country Netherlands 
Sector Academic/University 
PI Contribution David Hill performed several genome wide association studies.
Collaborator Contribution The group leaders were responsible for the development of the genomic SEM method.
Impact This collaboration resulted in the method of Genomic SEM being published in Nature Human Behaviour.
Start Year 2017
 
Description Collaboration with the University of Texas at Austin and the Vrije Universiteit Amsterdam - David Hill 
Organisation University of Texas at Austin
Country United States 
Sector Academic/University 
PI Contribution David Hill performed several genome wide association studies.
Collaborator Contribution The group leaders were responsible for the development of the genomic SEM method.
Impact This collaboration resulted in the method of Genomic SEM being published in Nature Human Behaviour.
Start Year 2017
 
Description Cox - Interconnectivity of Cerebral Sites - Colab. Pilot 
Organisation Lagos State University
Department Department of Computer Science
Country Nigeria 
Sector Academic/University 
PI Contribution Provided the concept and neuranatomical basis for development of a study specific method for identifying and measuring white matter connectivity between cerebral regions in older participants.
Collaborator Contribution The proposed study represents an international collaborative effort that marries expertise in neuropsychology, neuroanatomy, computer science and ageing research.
Impact A method for exploiting manual frontal lobe parcellations to measure specific site-to-site white matter connectivity in the brains of older persons. In addition to the method development, several manuscripts are planned which will examine the cognitive correlates of individual differences in intra-frontal and fronto-hippocampal connections. Preliminary results presented at two conferences (OHBM 2014 by Aribisala, and ISMRMB 2014 by Cox). Manuscript in preparation, collaboration with Psychiatry at UoE (Prof Lawrie) using this method in preliminary stages. Additional development work planned for use in the Lothian Birth cohorts.
Start Year 2013
 
Description Delbox as an activation task - Tieges 
Organisation Johns Hopkins University
Country United States 
Sector Academic/University 
PI Contribution Collaborative projects (until 2018) between the University of Edinburgh and Johns Hopkins University, US: Use of Delbox as an activation task-associated with attention in measurement of brain function using functional near-infrared spectroscopy (fNIRS). The Delbox will be used in several studies which are supported by Hitachi with funding and equipment.
Collaborator Contribution Their academic expertise.
Impact The first scientific paper is submitted.
Start Year 2016
 
Description EU Joint programme - Neurodegenerative Disease Research 
Organisation Lille University Hospital
Country France 
Sector Hospitals 
PI Contribution This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Collaborator Contribution This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Impact This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Start Year 2013
 
Description EU Joint programme - Neurodegenerative Disease Research 
Organisation Medical University of Graz
Country Austria 
Sector Academic/University 
PI Contribution This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Collaborator Contribution This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Impact This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Start Year 2013
 
Description EU Joint programme - Neurodegenerative Disease Research 
Organisation Paris Diderot University
Country France 
Sector Academic/University 
PI Contribution This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Collaborator Contribution This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Impact This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Start Year 2013
 
Description EU Joint programme - Neurodegenerative Disease Research 
Organisation Technical University of Munich
Country Germany 
Sector Academic/University 
PI Contribution This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Collaborator Contribution This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Impact This was a successful joint bid for funding under the EU Joint Programme's call "Working groups to inform cohort studies in Neurodegenerative disease research".
Start Year 2013
 
Description Genetics Team Lead for the PREVENT Dementia cohort study - Riccardo Marioni 
Organisation University of Edinburgh
Department Division of Psychiatry
Country United Kingdom 
Sector Academic/University 
PI Contribution I was invited to be the Genetics Team Lead for the PREVENT Dementia cohort study. We are finalising the collection of baseline data in the 700 participants and will start generating omics data in Spring 2019.
Collaborator Contribution Their expertise
Impact Data collection begins this spring
Start Year 2018
 
Description Geographical variation and environmental risk factors for dementia - Russ 
Organisation Health Statistics Unit
Country Italy 
Sector Public 
PI Contribution Analyse data available on dementia risk factors in an Italian population study.
Collaborator Contribution Provide data.
Impact Brief report due to be submitted for publication with other papers planned.
Start Year 2015
 
Description Geographical variation and environmental risk factors for dementia in Chile - Russ 
Organisation University of Talca
Country Chile 
Sector Academic/University 
PI Contribution This work is at a preliminary stage but my Chilean colleagues have provide data and I have analysed them
Collaborator Contribution Provided data.
Impact Brief report about to be submitted for publication; others planned.
Start Year 2015
 
Description Geographical variation and environmental risk factors for dementia in Japan - Russ 
Organisation Hokkaido University
Country Japan 
Sector Academic/University 
PI Contribution This work is at a preliminary stage but my Japanese colleagues have agreed to collaborate and provide data; I will analyse these.
Collaborator Contribution This work is at a preliminary stage but my Japanese colleagues have agreed to collaborate and provide data; I will analyse these.
Impact None as yet.
Start Year 2015
 
Description Geographical variation and environmental risk factors for dementia in New Zealand - Russ 
Organisation Auckland University of Technology (AUT)
Country New Zealand 
Sector Academic/University 
PI Contribution This is at a preliminary stage. We are discussing availability of data and an exchange visit by Dr Katherine Walesby is planned for this year.
Collaborator Contribution Provide data.
Impact None as yet.
Start Year 2015
 
Description Geographical variation in dementia - Russ 
Organisation Rush University
Country United States 
Sector Academic/University 
PI Contribution Applied to use their Religious Orders Study data and this has recently been approved.
Collaborator Contribution Provided data.
Impact Publications are being prepared.
Start Year 2015
 
Description Gow - A Tablet for Healthy Ageing 
Organisation University of Zurich
Country Switzerland 
Sector Academic/University 
PI Contribution Gow contributed to the development of a new research programme, A Tablet for Healthy Ageing, including obtaining funding from The Dunhill Medical Trust.
Collaborator Contribution Contributed to the development of a new research programme, A Tablet for Healthy Ageing, including obtaining funding from The Dunhill Medical Trust.
Impact This is a new research programme to develop a supported intervention programme utilising tablet PCs and other technologies to improve the health and well-being of older adults. The programme received funding from The Dunhill Medical Trust and is employing a post-doctorate research fellow based at Heriot Watt University.
Start Year 2014
 
Description Gow - School of Built Environment, Heriot Watt University 
Organisation Heriot-Watt University
Country United Kingdom 
Sector Academic/University 
PI Contribution Contributing expertise in cognitive ageing to a paper looking at housing built year and residence duration using the US NHANES study.
Collaborator Contribution Contributing expertise in the built environment to a paper looking at housing age and residence duration and cognitive function.
Impact This collaboration resulted in a paper which is currently under review, and a further application to access UK Biobank data. Shiue, I. & Gow, A. J. (under review). Housing built year and residence duration are associated with cognitive function in the elderly: US NHANES, 1999-2002.
Start Year 2014
 
Description HAGIS or THSLS - Scottish Longitudinal (cohort) study 
Organisation University of Dundee
Country United Kingdom 
Sector Academic/University 
PI Contribution Deary and Fawns-Ritchie from CCACE are providing expertise in cognitive testing to form the cognitive battery for the new planned Scottish longitudinal cohort. There is pilot funding in place (awarded to Stirling) from NIH.
Collaborator Contribution Partners are providing the organisation of the planned cohort and the expertise in economic and other social aspects of the data which will be gathered from the new cohort.
Impact Pilot grant awarded from NIH.
Start Year 2013
 
Description HAGIS or THSLS - Scottish Longitudinal (cohort) study 
Organisation University of Stirling
Country United Kingdom 
Sector Academic/University 
PI Contribution Deary and Fawns-Ritchie from CCACE are providing expertise in cognitive testing to form the cognitive battery for the new planned Scottish longitudinal cohort. There is pilot funding in place (awarded to Stirling) from NIH.
Collaborator Contribution Partners are providing the organisation of the planned cohort and the expertise in economic and other social aspects of the data which will be gathered from the new cohort.
Impact Pilot grant awarded from NIH.
Start Year 2013
 
Description Human episodic memory - Davies/Deary 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Title: Integrated systems approach identifies genetic nodes and network for human episodic memory This collaboration is based in the UK. Genome-wide association analyses of memory phenotypes were performed on the Lothian Birth Cohorts in an attempt to replicate findings from a co-expression network analysis performed on human hippocampus samples.
Collaborator Contribution See above
Impact We were able to successfully replicate these findings and a manuscript has been submitted. This collaboration is multi-disciplinary, it involves genetics, psychology (cognition), genomic medicine, Clinical neurogenetics, and neurology.
Start Year 2014
 
Description Human episodic memory - Davies/Deary 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Title: Integrated systems approach identifies genetic nodes and network for human episodic memory This collaboration is based in the UK. Genome-wide association analyses of memory phenotypes were performed on the Lothian Birth Cohorts in an attempt to replicate findings from a co-expression network analysis performed on human hippocampus samples.
Collaborator Contribution See above
Impact We were able to successfully replicate these findings and a manuscript has been submitted. This collaboration is multi-disciplinary, it involves genetics, psychology (cognition), genomic medicine, Clinical neurogenetics, and neurology.
Start Year 2014
 
Description International genetics collaboration investigating runs of homozygosity (ROHgen) 
Organisation University of Edinburgh
Department Centre for Population Health Sciences
Country United Kingdom 
Sector Academic/University 
PI Contribution This is an international collaboration investigating the effects of runs of homozygosity on a number of health-related traits including cognition. Manuscript in preparation.
Collaborator Contribution This is an international collaboration investigating the effects of runs of homozygosity on a number of health-related traits including cognition. Manuscript in preparation.
Impact Manuscript published.
Start Year 2014
 
Description Interstellar Initiative 
Organisation Columbia University
Country United States 
Sector Academic/University 
PI Contribution Selected for the Japan Agency for Medical Research and Development and the New York Academy of Sciences' Interstellar Initiative (March 2017-February 2018). I am one of 50 international early career researchers in neuroscience, regenerative medicine, and cancer selected for this scheme which consists of two intensive funding bid development meetings with mentoring hosted by the NYAS and $40,000 funding for each team of two or three to enhance their application to funding agencies.
Collaborator Contribution Academic expertise.
Impact None as yet.
Start Year 2017
 
Description Interstellar Initiative 
Organisation Osaka University
Country Japan 
Sector Academic/University 
PI Contribution Selected for the Japan Agency for Medical Research and Development and the New York Academy of Sciences' Interstellar Initiative (March 2017-February 2018). I am one of 50 international early career researchers in neuroscience, regenerative medicine, and cancer selected for this scheme which consists of two intensive funding bid development meetings with mentoring hosted by the NYAS and $40,000 funding for each team of two or three to enhance their application to funding agencies.
Collaborator Contribution Academic expertise.
Impact None as yet.
Start Year 2017
 
Description Lingo Flamingo social enterprise 
Organisation Social Enterprise UK
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Intellectual and research expertise to measure the cognitive effects of language learning on older adults.
Collaborator Contribution Provide language courses and tutors to adult learners.
Impact None to date as the collaboration has only recently formed.
Start Year 2016
 
Description MAGIC - international glycaemic traits genetics consortium 
Organisation MAGIC
Country United Kingdom 
Sector Public 
PI Contribution The is an international glycaemic traits genetics consortium. Current work is focussed on analysis of exome chip data.
Collaborator Contribution The is an international glycaemic traits genetics consortium. Current work is focussed on analysis of exome chip data.
Impact Manuscript in preparation.
Start Year 2014
 
Description MRC Integrative Epidemiology Unit in Bristol partnership - David Hill 
Organisation University of Bristol
Department MRC Integrative Epidemiology Unit
Country United Kingdom 
Sector Academic/University 
PI Contribution My contributions to this were to supply data, as well as to assist in the interpretation and write up of the manuscript
Collaborator Contribution Perform the analyses, and to draft the manuscript.
Impact This has resulted in two papers submitted (Anderson, E. L., (2019) and Davies et al., (20019)). Both of these manuscripts utilise bivariate Mendelian randomisation to examine the unique effects education and intelligence have on Alzheimer's disease and a broad range of health and anthropometric variables.
Start Year 2017
 
Description Molecular genetic data to inform about the causes of socioeconomic differences - David Hill 
Organisation Karolinska Institute
Country Sweden 
Sector Academic/University 
PI Contribution David Hill leads a project aiming to use molecular genetic data to inform about the causes of socioeconomic differences.
Collaborator Contribution MRC Integrative Epidemiology Unit in Bristol performed a causal analysis using the data provided by David Hill. Karolinska Institutet, UCL Institute of Neurology in London, provided access to data on cell-type specific gene expression found in cortical tissues. NHS Blood and Transplant, Oxford and the National Institute for Health Research Blood and Transplant Unit in Donor Health and Genomics, University of Cambridge provided GWAS data.
Impact David Hill is currently working on corrections of the manuscript that details the project's findings.
Start Year 2017
 
Description Molecular genetic data to inform about the causes of socioeconomic differences - David Hill 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution David Hill leads a project aiming to use molecular genetic data to inform about the causes of socioeconomic differences.
Collaborator Contribution MRC Integrative Epidemiology Unit in Bristol performed a causal analysis using the data provided by David Hill. Karolinska Institutet, UCL Institute of Neurology in London, provided access to data on cell-type specific gene expression found in cortical tissues. NHS Blood and Transplant, Oxford and the National Institute for Health Research Blood and Transplant Unit in Donor Health and Genomics, University of Cambridge provided GWAS data.
Impact David Hill is currently working on corrections of the manuscript that details the project's findings.
Start Year 2017
 
Description Molecular genetic data to inform about the causes of socioeconomic differences - David Hill 
Organisation University of Bristol
Department MRC Integrative Epidemiology Unit
Country United Kingdom 
Sector Academic/University 
PI Contribution David Hill leads a project aiming to use molecular genetic data to inform about the causes of socioeconomic differences.
Collaborator Contribution MRC Integrative Epidemiology Unit in Bristol performed a causal analysis using the data provided by David Hill. Karolinska Institutet, UCL Institute of Neurology in London, provided access to data on cell-type specific gene expression found in cortical tissues. NHS Blood and Transplant, Oxford and the National Institute for Health Research Blood and Transplant Unit in Donor Health and Genomics, University of Cambridge provided GWAS data.
Impact David Hill is currently working on corrections of the manuscript that details the project's findings.
Start Year 2017
 
Description Risk factors for dementia - Russ 
Organisation University of Tokyo
Country Japan 
Sector Academic/University 
PI Contribution "Geographical variation in and environmental risk factors for dementia in Japan" 2016 - Tokyo University, Japan & Oita University, Japan. Contributions: This work is at a preliminary stage but my Japanese colleagues have agreed to collaborate and provide data; I will analyse these.
Collaborator Contribution Japanese colleagues have agreed to collaborate and provide data
Impact None as yet. Papers are underway.
Start Year 2016
 
Description Scottish Data Linkage and Sharing Service / NRS 
Organisation Government of Scotland
Department Data Sharing and Linkage Service (DSLS)
Country United Kingdom 
Sector Public 
PI Contribution The research team contributed expertise in cognitive epidemiology and feedback on our experiences of data linkage. Ultimately the team will contribute data from the Scottish Mental Survey 1947. The team also suggested a suitable consultant for completion of a scoping project, and hosted and supervised that consultant for the duration of the 3-month project.
Collaborator Contribution The NRS team will contribute linkage between SMS1947 and National Registration 1939 databases. Funds were provided for consultancy work as part of a scoping project to identify suitable databases for linkage.
Impact The linkage between SMS1947 and 1939 national registration databases will enhance the tracing of the SMS1947 group. The scoping project led to the production of an extensive report on the use of the SMS1947 as a 'pathfinder' project for the new Data Sharing and Linkage Service currently under development in Scotland.
Start Year 2013
 
Description Scottish Data Linkage and Sharing Service / NRS 
Organisation National Records of Scotland
Country United Kingdom 
Sector Public 
PI Contribution The research team contributed expertise in cognitive epidemiology and feedback on our experiences of data linkage. Ultimately the team will contribute data from the Scottish Mental Survey 1947. The team also suggested a suitable consultant for completion of a scoping project, and hosted and supervised that consultant for the duration of the 3-month project.
Collaborator Contribution The NRS team will contribute linkage between SMS1947 and National Registration 1939 databases. Funds were provided for consultancy work as part of a scoping project to identify suitable databases for linkage.
Impact The linkage between SMS1947 and 1939 national registration databases will enhance the tracing of the SMS1947 group. The scoping project led to the production of an extensive report on the use of the SMS1947 as a 'pathfinder' project for the new Data Sharing and Linkage Service currently under development in Scotland.
Start Year 2013
 
Description UK Biobank 
Organisation University of Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution We provide statistical analysis and expertise on the cognitive and personality associated variables in a large collaboration aimed at studying associations between behavioural and medical outcomes in UK Biobank.
Collaborator Contribution They provide expertise in epidemiology and psychiatric disorders.
Impact Publications: 24884621, 24336235 , 24282498
Start Year 2013
 
Description UK Dementia Platform 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution Ian Deary is on the Executive Committee and the Scientific Steering Group of the UK dementias platform, which has attracted about £12million of core funding and has already added to that with about £40m in the MRC's clinical research infrastructure award. Also, from CCACE, John Starr, Jean Manson and Cathie Sudlow are on the scientific steering committee. Ian Deary and John Starr lead a work package which relates to enhancing cognitive testing in the UK Biobank sample in order to make it a dementia-ready cohort. Cathie Sudlow leads a work package which is aiming to conduct ascertainment of dementia in the UK Biobank sample.
Collaborator Contribution As above.
Impact This collaboration has attracted about £12million of core funding and has already added to that with about £40m in the MRC's clinical research infrastructure award.
Start Year 2013
 
Description UK Dementia Platform 
Organisation Johnson & Johnson
Country United States 
Sector Private 
PI Contribution Ian Deary is on the Executive Committee and the Scientific Steering Group of the UK dementias platform, which has attracted about £12million of core funding and has already added to that with about £40m in the MRC's clinical research infrastructure award. Also, from CCACE, John Starr, Jean Manson and Cathie Sudlow are on the scientific steering committee. Ian Deary and John Starr lead a work package which relates to enhancing cognitive testing in the UK Biobank sample in order to make it a dementia-ready cohort. Cathie Sudlow leads a work package which is aiming to conduct ascertainment of dementia in the UK Biobank sample.
Collaborator Contribution As above.
Impact This collaboration has attracted about £12million of core funding and has already added to that with about £40m in the MRC's clinical research infrastructure award.
Start Year 2013
 
Description UK Dementia Platform 
Organisation Newcastle University
Country United Kingdom 
Sector Academic/University 
PI Contribution Ian Deary is on the Executive Committee and the Scientific Steering Group of the UK dementias platform, which has attracted about £12million of core funding and has already added to that with about £40m in the MRC's clinical research infrastructure award. Also, from CCACE, John Starr, Jean Manson and Cathie Sudlow are on the scientific steering committee. Ian Deary and John Starr lead a work package which relates to enhancing cognitive testing in the UK Biobank sample in order to make it a dementia-ready cohort. Cathie Sudlow leads a work package which is aiming to conduct ascertainment of dementia in the UK Biobank sample.
Collaborator Contribution As above.
Impact This collaboration has attracted about £12million of core funding and has already added to that with about £40m in the MRC's clinical research infrastructure award.
Start Year 2013
 
Description UK Dementia Platform 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Ian Deary is on the Executive Committee and the Scientific Steering Group of the UK dementias platform, which has attracted about £12million of core funding and has already added to that with about £40m in the MRC's clinical research infrastructure award. Also, from CCACE, John Starr, Jean Manson and Cathie Sudlow are on the scientific steering committee. Ian Deary and John Starr lead a work package which relates to enhancing cognitive testing in the UK Biobank sample in order to make it a dementia-ready cohort. Cathie Sudlow leads a work package which is aiming to conduct ascertainment of dementia in the UK Biobank sample.
Collaborator Contribution As above.
Impact This collaboration has attracted about £12million of core funding and has already added to that with about £40m in the MRC's clinical research infrastructure award.
Start Year 2013
 
Description UK Dementia Platform 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution Ian Deary is on the Executive Committee and the Scientific Steering Group of the UK dementias platform, which has attracted about £12million of core funding and has already added to that with about £40m in the MRC's clinical research infrastructure award. Also, from CCACE, John Starr, Jean Manson and Cathie Sudlow are on the scientific steering committee. Ian Deary and John Starr lead a work package which relates to enhancing cognitive testing in the UK Biobank sample in order to make it a dementia-ready cohort. Cathie Sudlow leads a work package which is aiming to conduct ascertainment of dementia in the UK Biobank sample.
Collaborator Contribution As above.
Impact This collaboration has attracted about £12million of core funding and has already added to that with about £40m in the MRC's clinical research infrastructure award.
Start Year 2013
 
Title DelApp - Tieges 
Description The software source code for the current prototype of the DelApp has been written by Lothian NHS co-investigators on the project. The source code is protected by copyright. 
IP Reference  
Protection Copyrighted (e.g. software)
Year Protection Granted 2016
Licensed No
Impact This software has led to the development of potential clinical tool: DelApp. This is a software test for detecting attentional deficits in delirium [at the validation stage]. The value of the DelApp study was recognised in the oral presentation prize being awarded at the European Delirium Association meeting in November 2016.
 
Title Delbox versions 1 and 2 - Alasdair MacLullich 
Description A patent has been filed for a new computerised instrument for the detection of attentional deficits in delirium (the "Delbox"). The University of Edinburgh has filed a patent to cover the key features of the DelApp test and patents have now been granted in the US and in Europe: US 9307940 'Apparatus and Methods for testing sustained attention and Delirium'; EP 2485645 'Testing Apparatus and Method'. Key data informing the patents were provided from the original, smaller MRC Developmental Pathway Finding Scheme (DPFS) grant (Delbox), and our current studies' results are consistent with these findings, strengthening the claims. 
IP Reference EP2485645 
Protection Patent granted
Year Protection Granted 2016
Licensed No
Impact The 'Delbox' mark 2 has now been developed as a result of an MRC Development Pathway Funding Scheme grant and is currently being tested on patients and volunteers, some of whom are accessed using CCACE resources. It has attracted interest from research groups outwith Edinburgh and once we have completed the validation work over the next few months we will make it commercially available. This process is still ongoing.
 
Title Liewald-Cox Heatmapper - Dave Liewald, Simon Cox 
Description Developed by the CCACE database manager Dave Liewald and CCACE Associate Simon Cox, the Heatmapper tool allows the quick and simple creation of high resolution figures to illustrate associations between variables of interest and sub-regions of the brain's cortex. 
Type Of Technology Software 
Year Produced 2016 
Open Source License? Yes  
Impact Beta version will be released in Spring 2016, and the first outputs are part of a publication in preparation: Cox SR, Bastin ME, Ritchie SJ, Dicke DA, Liewald DC, Munoz Maniega S, Redmond P, Royle NA, Pattie A, Valdes Hernandez MdelC, Corley J, Aribisala BS, McIntosh AM, Wardlaw JM, Deary IJ. Brain cortical characteristics of lifetime cognitive ageing. It will also be used to illustrate the results of future cortical analyses conducted by CCACE members in both the LBC and UK Biobank cohorts, and also used more widely by other researchers once it becomes available via the CCACE website. 
 
Title R package to implement Thomson's bonds model 
Description The Centre's statistician, Dr Mike Allerhand, developed an R package in order to implement the Bonds theory of intelligence first proposed by Godfrey Thomson. It has been described in: Bartholomew D. J, Allerhand M., Deary I. J., (2013). Measuring mental capacity: Thomson's bonds model and Spearman's g-model compared. Intelligence. 41:222-233. 
Type Of Technology Software 
Year Produced 2013 
Open Source License? Yes  
Impact The package is distributed open source through the Centre's website. 
 
Title Reference Tracts and Generative Models for Brain White Matter Tractography 
Description These were created and presented at Medical Image Understanding and Analysis: 21st Annual Conference, 2017, and the citation is the first paper above. These reference tracts improved the automatic segmentation of brain white matter tracts from diffusion MRI, and demonstrated that matching models can be successfully transferred to novel data. The availability of these tracts and models make the use of probabilistic neighborhood tractography in small testing datasets possible as it can bypass the need for training data. They have been made available through the "TractoR MRI analysis project" (http://www.tractor-mri.org.uk). TractoR is free soft­ware, avail­able un­der the GPL li­cence. The reference tracts are referred to in here http://www.tractor-mri.org.uk/reference-tracts. 
Type Of Technology Webtool/Application 
Year Produced 2017 
Open Source License? Yes  
Impact The availability of these tracts and models make the use of probabilistic neighborhood tractography in small testing datasets possible as it can bypass the need for training data. 
URL http://www.tractor-mri.org.uk
 
Description Talk at Age UK's Edinburgh and Lothians Meeting of Older People's Groups and Organisations and presentation on healthy ageing - Michelle Luciano 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Patients, carers and/or patient groups
Results and Impact Afternoon of talks and workshops about healthy ageing with people who help to organise activities and meetings for older people. The talks were focused on healthy ageing and top tips for staying sharp, based on evidence from the Lothian Birth Cohort studies.

The attendees reported that they would try to introduce new activities into their groups, including crafting, walking, book clubs, educational programmes.

Personal feedback included: "I will try and cut down sweets and pudding intake"; "Improve sleep, keep hydrated, and get back to daily run"; "Attempt to learn French"
Year(s) Of Engagement Activity 2018
 
Description "Financial Abuse of Older People" - Stuart Ritchie 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Third sector organisations
Results and Impact February 18 2016: took part in a seminar on Financial Abuse of Older People at Age UK, alongside members of the police, policymakers, and charity workers.
Year(s) Of Engagement Activity 2016
 
Description 'AgeWell' annual event - Stuart Ritchie 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact September 1 2016: gave a talk on the LBC1936 to the 'AgeWell' annual event (general public audience) at the University of Birmingham.
Year(s) Of Engagement Activity 2016
 
Description A Day in the Life of Edinburgh Neuroscience 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact CCACE also collaborated with Edinburgh Neuroscience on a short film Ages of the Brain: a Day in the Life of Edinburgh Neuroscience. Using film and sound clips submitted by research groups from across CCACE and Edinburgh Neuroscience, we put together a short film on the variety of Neuroscience research across Edinburgh, with a special emphasis on the ageing brain. The film premiered at a joint event on 30 June and has since been viewed on YouTube over 1,400 times (https://youtu.be/zQqIH5yY3-c).
Year(s) Of Engagement Activity 2015
URL https://youtu.be/zQqIH5yY3-c
 
Description ARUK donor talk - Riccardo Marioni 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Supporters
Results and Impact • Alzheimer's research communication to ~20 trustees and donors of Alzheimer's Research UK (Oct 2018)
Year(s) Of Engagement Activity 2018
 
Description Adam Smith Institute's 'Forum' event - Stuart Ritchie 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact December 3 2016: gave a talk on intelligence generally, including LBC1936 data, for the Adam Smith Institute's 'Forum' event (audience: general public).
Year(s) Of Engagement Activity 2016
 
Description Age UK Bake Sale 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact CCACE core staff and members help a bake sale in aid of Age UK in February 2016. The charity event was held in the Department of Psychology and was open to anyone who wanted to buy. Prizes were awarded for the cake that best linked to an area of research or study, and the most amusing design.
Year(s) Of Engagement Activity 2017
 
Description Age UK Disconnected Mind Internal Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Industry/Business
Results and Impact Presentations given by Drs Cox, Ritchie and Morton and Prof Deary to Age UK staff from across the organisation about study findings. This was followed by breakout sessions to discuss how the findings can be incorporated into Age UK practices. January 2015
Year(s) Of Engagement Activity 2015
 
Description Age UK For Later Life Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Third sector organisations
Results and Impact This is the annual conference of the UK's largest charity devoted to helping older people, Age UK. Professor Deary addressed the whole meeting on the topic of healthy cognitive ageing, ensuring a broad UK reach to workers in the older-age charity sector.
Year(s) Of Engagement Activity 2015
 
Description Age UK Symposium on Financial Abuse 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Stuart Ritchie contributed to a panel discussion/symposium held at Age UK in London in February 2016 on financial abuse of older people. The panel included representatives from Age UK, the Metropolitan Police, banks (HSBC, Santander, Lloyd's), and other academics. Dr Ritchie used research findings from the Lothian Birth Cohorts to discuss how age-related cognitive decline might increase vulnerability to financial abuse in older persons.
Year(s) Of Engagement Activity 2016
 
Description Age UK staff on LBC1936 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Third sector organisations
Results and Impact Age UK is one of the main founders of Professor Deary's Lothian Birth Cohorts projects on healthy cognitive ageing. This talk was one of a number given by Professor Deary and team members to a large number of workers at Age UK in order to bring them up to date with the aims, findings, and practical applications of the teams research on cognitive ageing. It is used by Age UK in order to produce information, including books and website information, on the risks and protective factors for normal cognitive ageing which is highly important for their members.
Year(s) Of Engagement Activity 2015
 
Description Ageing brain, ageing mind. Senior men's group - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Presentation about cognitive and brain ageing for a senior men's group, followed by questions and discussion.
Year(s) Of Engagement Activity 2018
 
Description Ageing intervention research at HWU - Alan Gow 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Third sector organisations
Results and Impact Ageing intervention research at HWU. Roundtable presentation to Age Scotland, Heriot-Watt University, Edinburgh, UK, 27th March 2018.
Local/national reach - impact was in developing new networks and connections between researchers in ageing/brain health at HWU and national charity partner (Age Scotland).
Year(s) Of Engagement Activity 2018
 
Description Artist collaboration - "The Strategy of the Genes" 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The artwork is made by Penelope Kay, Artist in Residence at the invitation of Prof. Andrew McIntosh. The concept for the artwork is inspired by Dr. Pippa Thomson, Lecturer in Psychiatric Genetics and Group Leader at the Institute of Genetics and Molecular Medicine (IGMM), Edinburgh.
The art project involves creating a 3D object that can be installed in either an art or science space and can be interacted with by the viewer, who might be a member of the public or a scientist. The object will resemble a board game where the playing pieces relate to the coded information used by geneticists. The board will be 50x50cm, and can placed on a freestanding table for exhibition.
Year(s) Of Engagement Activity 2017
 
Description BBC Filming of Dementia Buddies Scheme 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The BBC came to our research facility and filmed us having conversations with patients about their lived experience with dementia. We also gave the patients a tour of the facility and a seminar on our work.

The footage was shown on BBC Scotland TV, radio and bbc.co.uk.

Many people got in touch afterwards looking to take part.
Year(s) Of Engagement Activity 2018
URL https://www.bbc.co.uk/news/uk-scotland-edinburgh-east-fife-46589662
 
Description BBC Radio Scotland Brainwaves: How To Stay Sharp - Alan Gow 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Alan Gow contributed to the BBC Radio Scotland programme Brainwaves, presented by Pennie Latin (broadcast 7 and 11 February 2018). Alan discussed lifestyle factors that contribute to healthy cognitive ageing.
Year(s) Of Engagement Activity 2018
URL http://www.bbc.co.uk/programmes/b09qqmfg
 
Description BBC Radio Scotland Personal Best : Giving and Receiving - Alan Gow 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Alan Gow contributed to the BBC Radio Scotland programme Personal Best, presented by Gillian Russell (broadcast 17 and 22 December 2018). The programme explored the topics of health and wellbeing.
Year(s) Of Engagement Activity 2018
URL https://www.bbc.co.uk/programmes/m0001mxz
 
Description BBC Radio Scotland Personal Best: Couples' Coaching Cards & Growth Mindset - Alan Gow 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Alan Gow contributed to the BBC Radio Scotland programme Personal Best, presented by Gillian Russell: Couples' Coaching Cards & Growth Mindset (broadcast 12 and 17 February 2018). Alan Gow described the of impact different activities on thinking skills in older age.
Year(s) Of Engagement Activity 2018
URL http://www.bbc.co.uk/programmes/b09rk6s7
 
Description BBC The Twinstitute - Thomas Bak 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact BBC Show "The Twinstitute" participation with TH Bak. Carried out cognitive testing post-course and brief appearance in the show.
Year(s) Of Engagement Activity 2019
URL https://twitter.com/EdinUniCAHSSres/status/1093182434185801728
 
Description BBC Trust me I'm a doctor - Thomas Bak 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Carried out cognitive testing and actively participated and contributed to research for the BBC programme "Trust me I am a doctor" alongside my research colleagues. Appearance in the show.
Year(s) Of Engagement Activity 2018
URL https://twitter.com/BBCTrustMe/status/1037415820392116224
 
Description BBC1 television series "Holding back the years" 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Bill Turnbull, star of BBC's Breakfast News TV, Strictly Come Dancing, Classic FM etc., came to the Psychology department on 23rd January 2017 with a BBC film crew to find out about the Lothian Birth Cohort 1936 (LBC1936)/Disconnected Mind study.

BBC1 are planning a series in the Spring called 'Holding back the years'. Each programme will feature a celebrity revisiting a place that means a lot to them, and the programmes will have a focus on the processes of human ageing. Mr Turnbull was at the University of Edinburgh in the 1970's (he shared a flat with Gordon Brown for a term!), and so his programme is based here. It was natural that, to find out more about ageing, and with an Edinburgh locus, he and the BBC filming team visited the LBC1936. A busy afternoon's filming was filled with his interviewing LBC1936 Director Ian Deary, speaking with about a dozen of the LBC1936 participants, and seeing and taking part in some cognitive testing. Look out for the series, especially the Edinburgh-based Bill Turnbull programme in a few months' time.
Year(s) Of Engagement Activity 2017
URL http://www.ccace.ed.ac.uk/node/340
 
Description BMJ picture of the week 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact The 'Picture of the Week' in the BMJ (Vol 348, issue 7964) showed two brain tractography images from the Brain Research Imaging Centre and from the Clinical Research Imaging Centre, both part of Edinburgh Neuroscience at the University of Edinburgh. The larger picture is from the LBC cohort (Lothian Birth Cohort) courtesy of Dr. Mark Bastin.

The image has now been seen by a wide variety of people including public and collaborators/peers. It raises awareness of our brain and cognitive work among healthy older people, and helps people understand the advances which imaging science have made in illustrating age-related brain changes.
Year(s) Of Engagement Activity 2014
 
Description BRAINS workshop August 2014 - Wardlaw 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact The workshop in August 2014 aimed to introduce the "Brain images of normal subjects" bank, which is being developed by imaging centres across Scotland. the aim is to collect data from across the lifecourse in order to create BRAINS atlases and support image analysis research and clinical reporting of brain images.

Widened interest in the BRAINS bank and informed peers and public about its existence and usefulness.
Year(s) Of Engagement Activity 2014
 
Description Bak - Bilingualism media coverage 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Two papers of Bak's published in November 2013 (Alladi et al, Neurology) and June 2014 (Bak et al, Annals of Neurology) produced great interest in the media with ca. 400 press reports across the world for each of them (including North & South America, most of Europe, Middle East, India and China), in popular (USA Today, Metro) as well as high reputation (Der Spiegel, Corriere della Sera) newspapers. This included full interviews (Observer, El Mundo) as well as radio and TV interviews (BBC, Canadian TV). The BBC article devoted to this work was the most tweeted one on the day of publication (2 June 2014). The interest persists with regular invitations for interviews. Together with Bilingualism Matters (BM) and The Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE) I conducted a twitter session in July 2014 and applied for a joint event at the Edinburgh Science Festival in April 2015. The Principal has sent Bak a personal letter of acknowledgement and selected his work to feature in the Annual Review of the University.



When the communications office at the University of Edinburgh tried to estimate the number of media outlets which this story reached, it ran to the hundreds, covering many international television, radio and printed and web-based news outlets. Together with CCACE, Bak has applied to run a joint event at the Edinburgh International Science Festival in April 2015. 'Speaking Two Languages Benefits the Ageing Brain' YouTube video has been watched over 2,400 times http://youtu.be/emNrOSLJseo.
Year(s) Of Engagement Activity 2014
URL http://youtu.be/emNrOSLJseo
 
Description Bak - Cambridge Bilingualism network 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Thomas Bak was invited to give a talk on 'Bilingualism across the lifespan' at the Cambridge Bilingualism Network at Cambridge University in 2014. This talk covered research findings using data from the Lothian BIrth Cohort 1936.

This was an excellent opportunity to showcase Bak's work on bilingualism and ageing, using data from the Lothian Birth Cohort 1936 study.
Year(s) Of Engagement Activity 2014
 
Description Bak - dementia, aphasia and movement disorders 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Thomas Bak regularly presents talks to patient and carer groups, in the area of dementia, aphasia and movement disorders (often under the auspices of charities such as Alzheimer Society or Progressive Supranuclear Palsy PSP Association).

The positive feedback received from these events is exemplified by a message he got from one of the organisers: "Just a note to thank you so much for such a thoughtful and helpful presentation on Tuesday. We all benefited greatly from your extensive understanding of this challenging illness and your clear empathy with people & their carers who are coming to terms with the diagnosis and adjusting to life and all the uncertainty they face. It was so encouraging to hear of an approach which looked at what is preserved and not just at the decline in capacity".
Year(s) Of Engagement Activity 2014
 
Description Being smart and staying smart - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Presentation 'Being smart and staying smart' to the Genetics and Genomics Principal Investigators' Group, Roslin Institute, University of Edinburgh. Edinburgh, UK, July 2018.
Year(s) Of Engagement Activity 2018
 
Description Brain Box 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The CCACE Director and Knowledge Exchange Officer have been involved in the development of a 'Brain Box'. This is a portable workshop/festival resource to excite children and adults about the brain, how it works and the changes it goes through in a lifetime. It is a resource for guided workshops, festivals, exhibitions and events that would over time develop an online 'personality' tweeting about its day with photos, comments and quotes: see it on Twitter @brainboxone.

This project is still in the development phase and received £4956 from the MRC Regional Communications Fund. Workshops are being planned as part of the Edinburgh International Science Festival 14-18 April 2015.
Year(s) Of Engagement Activity 2014
 
Description Brain Training on Trial - Alan Gow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Presentation exploring issues related to the brain training industry, at the Edinburgh Festival Fringe as part of Skeptics on the Fringe, Edinburgh Skeptics Society, Edinburgh, UK, 20th August 2018.
Year(s) Of Engagement Activity 2011,2018
 
Description Brain Training on Trial Fringe show 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Gow developed and delivered an hour-long show, "Brain Training on Trial", as part of the Edinburgh Festival Fringe, under the banner of Edinburgh Beltane's Cabaret of Dangerous Ideas. The show was attended by around 60 people. The trailer on You Tube had 533 views and 5 likes.

The event itself sparked discussion and questions afterwards. Gow produced a "summing-up" video on 20th October 2014, which has had 68 views on You Tube. Gow also wrote a blog article on the subject of Brain Training on Trial on the Research the Headlines blog, which is followed by 88 people.
Year(s) Of Engagement Activity 2014
URL http://researchtheheadlines.org/2014/09/09/brain-training-on-trial/
 
Description Bringing intelligence to life - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Bringing intelligence to life. Invited address to the Human Genetics Group, Wellcome Genome Campus, Hinxton, Cambridge. Cambridge, UK, March 2018.
Year(s) Of Engagement Activity 2018
 
Description British Academy debate 29th April 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The Centre director, Ian Deary, presented the work of the Centre as part of a debate entitled The best years of our lives? on 29th April 2014. This was very well attended - around 300 people - and well publicised by the British Academy and beyond. The debate was chaired by well-known broadcaster Sally Magnusson (who recently wrote a book on dementia which had extended interviews with Ian Deary and John Starr), and also had contributions from Age UK's Professor James Goodwin, Alzheimers Scotland's Henry Simmons, and Professor Catharine Ward-Thompson.

The event was well publicised and recordings of the debate made available through social media and the British Academy website. There was a lively discussion after the debate.
Year(s) Of Engagement Activity 2014
 
Description CCACE - Training courses 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact In 2012, 2013 and 2014 CCACE ran a number of short taining courses. These included "introduction to R programming", "longitudinal modelling", and "systematic reviews and meta-analysis".

R programming course has run 7 times between 2012-2014 with over 200 attendees.

SR course - 2 sessions. Dec 2012 (n = 16), November 2013 (n = 18).

Longitudinal modelling - 1 session in November 2013 (n = 50).

We have increased the visibility of CCACE and the skills that we can offer to a wider academic audience.
Year(s) Of Engagement Activity 2012,2013,2014
URL http://www.ccace.ed.ac.uk/students-training/training
 
Description CCACE Social Media 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact CCACE has a significant following on social media (912 on Facebook; 701 on Twitter). Over the past year, the most watched research video was A Slower DNA Clock Predicts Longer Life by Dr Riccardo Marioni (https://youtu.be/bmpv-LDuL7s), viewed 748 times.
Year(s) Of Engagement Activity 2014,2015
URL https://youtu.be/bmpv-LDuL7
 
Description CCACE YouTube channel ccacevideo 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Since 2011 CCACE has posted 29 videos about events, research and the Centre on its YouTube channel.

The CCACE video channel has 36 subscribers and its videos have been viewed 13,302 times (as of 7th November 2014).
Year(s) Of Engagement Activity 2011,2012,2013,2014
URL http://www.youtube.com/ccacevideo
 
Description CCACE celebrates Scottish research cohorts 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact Event held at Edinburgh's General Assembly Hall, June 2018. Hundreds of participants and researchers from Scottish cohort studies came together to celebrate their contribution to, and crucial role in, healthcare research. The day's programme covered research across the entire human lifespan, beginning with a presentation by Professor James Boardman on effects of premature birth, and ending with a talk from Professor David Batty on regional disparities in mortality. The event also offered a unique opportunity to survey the opinion of current Scottish cohort participants on future uses and sharing of their data.
Year(s) Of Engagement Activity 2018
URL https://www.youtube.com/watch?v=GJBbqOq4qa8
 
Description CCACE eNewsletter 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The Centres' Knowledge Exhange Officer produces a quarterly CCACE Newsletter detailing news and updates of Centre acitivity.

The Summer 2014 newsletter was circulated to 447 recipients with 190 (43%) opening it and 83 (19%) clicking on several of its links. For the Winter 2013/14 newsletter these figures were 446, 209 (47%) and 89 (20%).

In November 2011 this is circulated to a distribution list of over 220. Statistics from the January 2011 edition showed that ~60% opened the newsletter, and ~40% clicked on several of its links.
Year(s) Of Engagement Activity 2010,2011,2012,2013,2014
 
Description CCACE media coverage 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact 21 Mar 2014 - LBC1921/1936 feature in review of UK population studies by MRC
17 April 2014 - LBC reunion covered by STV News
Spring 2014 MRC Network- coverage of Ian Deary's workspace
12th May 2014 "Edinburgh and Aberdeen depression study given £4.7m funds" - BBC News,; STRADL
11 June 2014- 9pm 'Frontier's - BBC Radio 4, - Latest thinking about our brain power in old age (Lothian Birth Cohort)
2 Jul 2014 - BRIC picture of the week
17 Jul 2014 - Bilingualism: Thomas Bak's paper - multiple media coverage. Answered live questions Bilingualism Matters; "Learning second language 'slows brain ageing'', BBC News June 2nd; The Australian news June 2nd; YouTube video >3,000 views: http://youtu.be/emNrOSLJseo
11 Aug 2014 - Stuart Ritchie on Infinite Monkey Cage -
11 Aug 2014 - Stuart Ritchie - visual processing and age on Good Morning Scotland, BBC Radio Scotland. YouTube video http://youtu.be/vWkgP5sWCNA
9 Oct 2014 - UK Dementia Platform Press Release http://www.ed.ac.uk/news/2014/dementia-190614 YouTube Video: http://youtu.be/xyer_t-X3lQ
30 Oct 2014 Science Magazine Article http://t.co/LxkPicGrvi
6 Nov 2014 Height associated with increased risk of dementia. New study from Tom Russ http://t.co/73cNJzhk1U https://youtu.be/BojlhIJ_TI8
20 Nov 2014 Complex jobs protect memory - http://www.bbc.co.uk/news/health-30115497
3 Dec 2014 Genetic study of Memory (CHARGE Consortium) http://www.ed.ac.uk/news/2014/memory-261114
3 Dec 2014 Nice mention of recent @ccace results from @claudiahammond & @CathLoveday on @BBCRadio4's All in the Mind, at 24m 30: http://www.bbc.co.uk/programmes/b04svjbn
Dec 2014 DM results appearing in Age UK's Report of Trustees (p. 19): http://www.ageuk.org.uk/Documents/EN-GB/Corporate/age_uk_annual_report_2013_14.pdf?dtrk=true
15 Jan 2015 BBC Breakfast does a nice story on The Disconnected Mind / Lothian Birth Cohort as it begins Wave 4. http://t.co/rHpVx8SVQI
20 Jan 2015 £15m boost for Scotland's gene research | News | http://www.ed.ac.uk/news/2015/scottishgenomes-120115
30 Jan 2015 DNA Clock helps predict lifespan http://youtu.be/bmpv-LDuL7s?a http://www.ed.ac.uk/news/2015/dnaclock-300115
http://www.independent.co.uk/news/science/dna-clues-could-predict-when-people-will-die-10014400.html
3 Feb 2015 Scientists @CCACE have identified genes associated with people's cognitive function-how we process information http://www.ed.ac.uk/news/2015/genes-030215
YouTube Video: http://t.co/7KSyLzvD6o
11 Feb 2015 Smokers tend to have thinner brain cortex http://www.independent.co.uk/news/science/smokers-have-thinner-brain-cortex-and-could-have-impaired-thinking-10039128.html
Release: http://www.ed.ac.uk/schools-departments/clinical-sciences/edinburgh-imaging/news/smokers-cortex
1 Dec 2015 Does Being Bilingual Protect Your Brain? - Thomas Bak on All in the Mind, BBC Radio 4 http://www.bbc.co.uk/programmes/p039w8gf?ns_mchannel=social&ns_campaign=bbc_radio_4&ns_source=facebook&ns_linkname=radio_and_music
22 Dec 2016 - Advances in the Genetic Basis of Intelligence: articles in The Guardian and The Telegraph. Jan 2016 - STV News LBC participant Mr Scott and Dr Simon Cox interviewed about new National Museum of Scotland Exhibit. STV News (from 15:30) at http://player.stv.tv/episode/36pt/news-at-six-edinburgh-east-full/thu-07-jan-6-00-pm/
Jan 2016 - Health and Thinking Skills Linked to the Same Genes -
Year(s) Of Engagement Activity 2014,2015,2016
 
Description CCACE on Facebook: CCACEedinburgh 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact CCACE launched its Facebook page in 2011 featuring photographs, video and news about CCACE

147 people have "liked" the page so far, and actively share CCACE's newsfeeds.
Year(s) Of Engagement Activity 2011,2012,2013,2014
URL https://www.facebook.com/CCACEEdinburgh
 
Description CCACE public engagegement activities 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Jan 28th 2014 - Presented Disconnected Mind and CCACE 3D brain at Age UK's reception at St James's Palace hosted by HRH Prince Charles,
April 2014- LBC reunion To see coverage on STV visit http://news.stv.tv/east-central/272014-oaps-sit-same-test-for-eight-deca...
April 29th 2014 - Big debate -- the best years of our lives? - British Academy
May 16th 2014 - Gathering Intelligence: the life and work of Prof Sir Godfrey Thomson,
28 Oct 2014 Ian Deary presented at the launch of the Dementia Platform UK on 28 October 2015 at the Royal Society London
6 Nov 2014 - Lifelong Health and Wellbeing London - Zoe Tieges talks about development of DELBOX for diagnosis of delirium; Natalie Royle describes standardised ways of measuring older brains using brain imaging; Maria Valdez del Hernandez speaks about brain imaging stuff
19 Nov 2014 Ian Deary addressed the Age Scotland conference
20 Nov 2014 The Day Scotland Tested the Nations IQ part of Previously...Scotland's History Festival https://iqpreviously.eventbrite.co.uk
27 Nov 2014 Ian Deary gave keynote talk at Voluntary Health Scotland conference "Health, Wellbeing and Your Brain"
28th October 2014 - UK Dementia Platform launch, London,
14 Mar 2015 The Living Brain event at Cambo House Fife, 20 adults attended 3 hour session (talk from Ian Deary, interactive session with ID, RM and Helen Staton, showing of the Living Brain Film and open questions.
19 March 2015 Schools workshop at Davidsons Mains Primary School - 40 Children
9 April 2015 The Living Brain - Interactive panel discussion. Edinburgh International Science Festival - 80 Adult attendees.
14-18 April 2015 BrainBox Workshop - Edinburgh International Science Festival, National Museum of Scotland - 70 Children aged 8-12.
27 Aug 2015 Cabaret of Dangerous Ideas, Edinburgh Festival Fringe - Alan Gow presented "The Great British Brain Off" to 80 members of the general public.
October 2015 - Age: What is your number? Midlothian Science Festival evening event, 30 adult attendees.
November 2015 BrainBox Workshop - 20 Beaver Scouts.
Year(s) Of Engagement Activity 2014,2015
 
Description CCACE quarterly newsletter 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact CCACE has produced a quarterly newsletter since 2008. The newsletter mailing list has a varied audience of lay and scientists. It summarises major achievements of the Centre and our recent news items.
Year(s) Of Engagement Activity 2008,2009,2010,2011,2012
URL http://www.ccace.ed.ac.uk/news-events/latest
 
Description Cabaret of Dangerous Ideas - Bak 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Edinburgh Fringe Festival, event attended by ca. 80 people (the second highest attendance in the series); after the show approached to write a blog for British Medical Journal, which later got published as a paper, and give an interview to the Fringe Radio.
Year(s) Of Engagement Activity 2016
URL http://codi.beltanenetwork.org/event/codi-2016-language-lessons-on-the-nhs/thomas-bak/
 
Description Cafe Scientifique cockermouth - Pickersgill 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Martyn Pickersgill: 'Enhancing What? Enhancing Who? Enhancing Why? Social Aspects of the Human Enhancement Debate', Café Scientifique, Cockermouth, 19th November 2013 (speaker).

Interest and enthusiasm shown by attendees.
Year(s) Of Engagement Activity 2013
 
Description Cambo Winter Talks Series 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Professor Deary gave a talk on normal cognitive ageing followed by lively discussion at this small science festival. It was a accompanied by activities related to cognitive ageing that were conducted by him and other members of the CCACE Centre.
Year(s) Of Engagement Activity 2015
 
Description Centre for Dementia Prevention annual winter conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Title: Centre for Dementia Prevention annual winter conference: "Preventing Dementia: Advice and Advances"
Type: Public lecture
Audience: General public, predominantly local
November 2017
Description: Public lecture, 250 attended
Impact: Improved understanding about recent advances in dementia prevention
URLs: http://centrefordementiaprevention.com/2017/11/30/1753/
https://media.ed.ac.uk/search/searchkeyword/centre%20for%20dementia%20prevention
Year(s) Of Engagement Activity 2017
URL http://centrefordementiaprevention.com/2017/11/30/1753/
 
Description Centre for Educational Sociology Lecture - Lindsay Paterson 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Paterson, L. (2018), Scottish Education Policy: Why Surveys Matter, CES Briefing No. 66, June.
Year(s) Of Engagement Activity 2018
 
Description Cognition and a Mediterranean diet research paper - Luciano 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact There was considerable media interest in a paper examining the link between consuming a Mediterranean diet and brain shrinkage. CCACE member, Michelle Luciano, gave Live TV interview on BBC Breakfast, pre-recorded TV interview for a South Korean News Channel, 2 Live radio Broadcasts (BBC Reporting Scotland, BBC 3 Counties), and 1 pre-recorded radio broadcast (Radio Forth)

Various interviews were also given for print media:
5/01/17: (BBC online ) (i) (The Press and Journal) (The Belfast Telegraph) (The Daily Express) (The Sun) (Metro) (New Scientist online) (The Herald) (The LA Times online (USA)) (The Times) (The Independent) (The Daily Mail) (Huffington Post online) (NBC News online) (The Irish Examiner online (Ireland)) (The Edinburgh Evening News) (The Evening Express) (La Vanguardia (Spain)) (Indo-Asian New Service (India)) (U.S. Food Stafety (USA)) (herenciageneticayenfermedad blog (Argentina)) (Health News Review (USA)) (ForeignAffairs.co.nz (New Zealand)) (Yahoo! India) (Channel 3000 (USA)) (Proceso Digital (Honduras)) (Nutraceutical World (USA)) (Top Sante (France)) (Yahoo! Actualites (France)) (The Business Standard (India)) (MedIndia (India)) (Visao Online (Portugal)) (Slashdot (USA)) (WOAI (USA)) (The New York Times (USA)) (Radio-Canada (Canada)) (Carriere Adriatico (Italy)) (Expatica (Netherlands)) (Inc.com (USA)) (WWLP (USA)) (TVA Nouvelles (Canada)) (ladepeche.fr (France)) (China News Service (China)) (The New York Times online (USA)) (Adnkronos (Italy)) (CNN (USA)) (NBC News (USA)) (U.S. News & World Report (USA)) (EFE - International Service (Spain)) (The Irish Daily Mail (Ireland)) (MedIndia (India)) (Point (France)) (AGF (Netherlands)) (Gosalute (Italy)) (Panorama (Italy)) (The New Zealand Herald) (Health Daily Digest (India)) (International Business Times (USA)) (Newser (USA)) (El Semanario Limitless (Mexico)) (Tech Times (USA)) (Day (Argentina)) (NutraIngredients.com (France)) (Sunday World (Ireland)) (La Sicillia (Italy)) (Monthly Prescribing References (USA)) (ProHealth.com (USA)) (Courrier Picard (France)) (Digital Journal (USA)) (EMaxHealth (USA)) (Sarasota Herald-Tribune (USA))
Year(s) Of Engagement Activity 2016
 
Description Cognitive epidemiology interview - Geoff Der 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact CCACE member Geoff Der has given an interesting and wide-ranging interview about his work on intelligence, which you can hear through the link below. It includes a discussion on childhood intelligence, longevity and health, effects of maternal smoking and breast feeding on children's intelligence, and sex differences in intelligence.

Geoff told us, "This interview came about because a controversial blog post had claimed that intelligence was primarily inherited from one's mother and cited some of our work as important evidence of this. The blog gained a lot of publicity in the USA via social media and we were invited by the smartdrugsmarts website to give an interview on the research cited. However, before the interview could be arranged, a convincing rejoinder to the original blog had been published by the Forbes website. The smartdrugsmart website was still keen to go ahead with the interview as a more general piece about our research using the National Longitudinal Study of Youth. This is the result."
Year(s) Of Engagement Activity 2017
URL http://smartdrugsmarts.com/episode-158-intelligence-genetics/?utm_source=twitter&utm_campaign=post&u...
 
Description Cohort and Longitudinal Studies Enhancement Resources conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact This was an invited lecture in the evening following the Cohort and Longitudinal Studies Enhancement Resources' conference. It was at the British Library, it was ticketed at £8, and was sold out with a large waiting list. The lecture covered Professor Deary's team's work on healthy cognitive ageing using the follow-up studies of the Scottish Mental Surveys. The full lecture is available online at the CLOSER website. This was a good opportunity to spread the word on the research to a mixed group[p of longitudinal cohort researchers, lay public, and charity sector workers.
Year(s) Of Engagement Activity 2015
URL https://www.youtube.com/watch?v=0rxgundtPTI
 
Description Cox & Davies - U3A East Lothian 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Talk given by Simon Cox and Gail Davies to the University of the 3rd Age Haddington Science Group, East Lothian, UK. Title: Brain, genes and cognitive ageing in the Lothian Birth Cohort studies. May 2015.
Year(s) Of Engagement Activity 2015
 
Description Cox - Cafe Scientifique, Cockermouth 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Dr. Simon Cox gave a talk to the Café Scientifique in Cockermouth entitled: 'Postcards from your brain; we wish we were there. On the (mis)uses of brain imaging'. Illustrations of brain imaging were distributed to attendees in postcard form, and examples from the Disconnected Mind study among others were discussed as instances of appropriate MRI data usage. Now developed, Simon will also give this talk at future knowledge exchange events.

The talk was very successful with a great deal of interest and enthusiasm shown by attendees. Dr Cox hopes that this will lead to further invitations to similar events.
Year(s) Of Engagement Activity 2014
 
Description Cox - Colinton Literary Society, Feb 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Simon Cox presented a talk entitled New Adventures in Cognitive Ageing Research: The Lothian Birth Cohorts of 1921 & 1936 at The Colinton Literary Society, Edinburgh, UK. February. (c.50 attendees).

The event was successful in disseminating information on the work of the Centre and Lothian Birth Cohort studies to members of the public.
Year(s) Of Engagement Activity 2014
 
Description Cox - DRCMR, Copenhagen 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Postgraduate students
Results and Impact Talk (Design, challenges and pitfalls in life span studies) on a week-long course for PhD students at the Danish Research Centre for Magnetic Resonance, University of Copenhagen. Attended by ~40 students and staff.
Year(s) Of Engagement Activity 2016
URL http://www.drcmr.dk/events/event/166
 
Description Cox - Seniors USP launch 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Cox SR (2014) Work Package 3: The Lothian Birth Cohort 1936. Seniors USP Dissemination Group Launch Day, Glasgow, UK. May. (c.15 attendees).

This was an opportunity to share knowledge and plans for the MRC-funded Seniors USP study. It was attended by CCACE's collaborators and increased the opportunities for future collaborations and research.
Year(s) Of Engagement Activity 2014
 
Description Deary - AGE UK interview on Disconnected Mind / LBC1936 April 2014 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact This interview was a wide ranging description of the rationale for and achievements of the Disconnected Mind / Lothian Birth Cohort 1936 project for internal Age UK purposes. The aim was to inform a wide range of individuals within Age UK about the achievements of this cognitive ageing (and broader ageing) study in order that professionals within the Age UK charity organisation could be well informed when dealing with policy professionals external to the organisation and older people more generally.

Age UK is the largest older age-related charity in the UK. They provide evidence to the UK government and more broadly, for example to the G7 conference. One example of the reach of the Disconnected Mind project is that the Age UK CEO, Tom Wright, delivered a talk to the G7 conference in November 2014 in Tokyo, and used evidence from the Disconnected Mind project in his slides. Also, Age UK were influential in urging the current Conservative government to undertake a large dementia initiative which was announced at the G7/G8 conference and could be partly credited for the MRC's dementias platform UK initiative.
Year(s) Of Engagement Activity 2014
URL http://www.ageuk.org.uk/about-us/what-we-do/the-disconnected-mind/
 
Description Deary - British Academy Expert Workshop 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact With CCACE fellow-elect, Dr Stuart Ritchie, Ian Deary obtained funding for and organised this British Academy-funded workshop on processing speed and its importance for cognitive ageing in humans held in April 2014. Among the 13 attendees were international experts from the USA, Europe and the UK. Also, Professor James Goodwin for Age UK attended in order to achieve knowledge exchange and impact for the discussions.


All of the discussions were audio recorded and slides made available. There were several impacts. First, Ian Deary and Stuart Ritchie wrote a summary article for British Academy Review and this made available the questions and discussion on processing speed to other academics. Second, Professor James Thompson of University College London extensively reported several of the talks with their Powerpoint slides on his much-read psychology blog, which reaches academics and lay people. Third, Professor James Goodwin took the results and their impact back to Age UK with a view to discussing how these were relevant to Age UK's aims in helping older people.
Year(s) Of Engagement Activity 2014
 
Description Deary - Glasgow Centre for Population Health 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Invited seminar: Deary, I. J. (2014). Healthy cognitive ageing. Glasgow Centre for Population Health. Glasgow, UK, January. Ian Deary gave a talk on the follow-up studies of the Scottish Mental Surveys, especially the Lothian Birth Cohort studies of 1921 and 1936. It was described how these contribute to what we know about protective and risk factors for healthy cognitive ageing. The topic of dementia was also discussed. There was a lengthy question session afterwards and Professor Deary had drinks with the audience and had further discussion.

A video of the talk was placed on the GCPH website and has been viewed many times.
Year(s) Of Engagement Activity 2014
 
Description Deary - Healthy ageing LBC studies Inner Wheel Club Edinburgh 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Deary, I. J. (2014). Healthy ageing: clues from the Lothian Birth Cohorts of 1921 and 1936. The Inner Wheel Club of Edinburgh. Edinburgh, UK, February. Ian Deary gave a talk on the follow-up studies of the Scottish Mental Surveys, especially the Lothian Birth Cohort studies of 1921 and 1936. It was described how these contribute to what we know about protective and risk factors for healthy cognitive ageing. The topic of dementia was also discussed. There was a lengthy question session afterwards and Professor Deary took soup and sandwiches with the audience and had further discussion.

After this talk the organisers thought it was so important and successful that they passed on Professor Deary's details to other group organisers and subsequent invitations ensued.
Year(s) Of Engagement Activity 2014
 
Description Deary - Healthy cognitive ageing, York University 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Ian Deary was invited to give a seminar on Healthy cognitive ageing at the University of York, October 2014.

Interest and enthusiasm shown by attendees, and increased knowledge of the work of the Centre and LBC studies. The host, Dr Gary Lewis, after discussion with Professor Deary, has established plans for a new collaboration with the Lothian Birth Cohort studies.
Year(s) Of Engagement Activity 2014
 
Description Deary - Leith Probus Club 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Invited talk: Deary, I. J. (2013). The Lothian Birth Cohort 1936. Leith Probus Club. Edinburgh, UK, October. Ian Deary gave a talk on the follow-up studies of the Scottish Mental Surveys, especially the Lothian Birth Cohort studies of 1921 and 1936. It was described how these contribute to what we know about protective and risk factors for healthy cognitive ageing. The topic of dementia was also discussed. There was a lengthy question session afterwards and Professor Deary took tea with the audience and had further discussion.

After this talk the organisers thought it was so important and successful that they passed on Professor Deary's details to other group organisers and subsequent invitations ensued.
Year(s) Of Engagement Activity 2014
 
Description Deary - MRC Network spring 2014 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact The MRC's publication, Network, published an article on Centre Director Ian Deary's workspace, which showcased the work of the Centre in spring 2014.

As is typical with these sorts of magazine-type articles, it attracted a lot of comment and attention, and many people, as a result, asked Professor Deary and colleagues about the history of the Scottish Mental Surveys and the work of the Lothian Birth Cohorts.
Year(s) Of Engagement Activity 2014
 
Description Deary - Pilrig St Paul's Guild, Edinburgh 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Invited talk: Deary, I. J. (2013). The Scottish Mental Surveys and healthy cognitive and brain ageing. Pilrig St Paul's Guild. Edinburgh, UK, November. Ian Deary gave a talk on the follow-up studies of the Scottish Mental Surveys, especially the Lothian Birth Cohort studies of 1921 and 1936. It was described how these contribute to what we know about protective and risk factors for healthy cognitive ageing. The topic of dementia was also discussed. There was a lengthy question session afterwards and Professor Deary took tea with the audience and had further discussion.

After this talk the organisers thought it was so important and successful that they passed on Professor Deary's details to other group organisers and subsequent invitations ensued.
Year(s) Of Engagement Activity 2014
 
Description Deary Talk to Scottish Government Data Linkage Framework 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact Deary was invited to present results from the follow-up studies of the Scottish Mental Surveys as an exemplar of data linkage to the Scottish Government Data Linkage Framework.

The Scottish Mental Surveys as a resource formed an exemplar of data linkage, informing future government plans in data linkage services.
Year(s) Of Engagement Activity 2013
 
Description Della Sala - Treasure Island 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Sergio Della Sala was involved in advising on a schools engagement programme entitled "Treasure Island: Discussion Notes from a Neuroscience Perspective" during 2014.

Interest and enthusiasm shown by pupils attending events in the programme.
Year(s) Of Engagement Activity 2014
 
Description Della Sala - false memories, Terra Mexico 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Sergio Della Sala commented on a study claiming that the mind creates false memories, Terra Mexico, 20th August 2014.

This commentary was available in the public domain
Year(s) Of Engagement Activity 2014
 
Description Della Sala - neurolinguistic programming, Wired.it 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Sergio Della Sala featured in an article on Wired.it speaking about how neurolinguistic programming as a science does not exist, 4th February 2014.

This article was in the public domain.
Year(s) Of Engagement Activity 2014
 
Description Della Sala - tickling yourself, Sunday Times 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Sergio Della Sala featured in an article in The Sunday Times on 26th January 2014 on why it is not possible to tickle oneself.

This article was in the public domain.
Year(s) Of Engagement Activity 2014
 
Description Dementia Buddies Scheme - Szu-Han Wang 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Patients, carers and/or patient groups
Results and Impact Knowledge exchange between patients with dementia and researchers working on the biological aspects of dementia. Patients and carers visit us at our research labs and we speak to them about their lived experience. This has sparked much discussion with the patients.
Year(s) Of Engagement Activity 2018
 
Description Disconnected Mind newsletter - 2013+ 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact The Disconnected Mind project, which includes the Lothian Birth Cohort 1936 study and involves many of the Centre's members, produces a quarterly newsletter summarising study progress, impact and the latest research findings. This is distributed to approximately 126 funders and research collaborators across the UK.

The newsletter is sent to funders as well as research collaborators, and information on the study and its findings has been used by Age UK, the LBC1936 study's main funders, in their publications.
Year(s) Of Engagement Activity 2013,2014
 
Description Does language learning lead to healthier ageing? - Thomas Bak 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Blog for MEITS website
Year(s) Of Engagement Activity 2018
URL http://www.meits.org/blog/post/does-language-learning-lead-to-healthier-ageing
 
Description Drop-in activity at the Edinburgh International Science Festival 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Staff and students from CCACE hosted a drop-in activity stand at the National Museum of Scotland, with the theme: 'How Old Are You Really?' The aim was to draw attention to the many ways - other than chronological age - that researchers of ageing try to measure how old someone is. In a sign of how well received the stand was, there were queues to enter everyday due to reaching maximum visitor capacity.
Year(s) Of Engagement Activity 2009,2018
 
Description Edinburgh Festival Fringe - Alan Gow 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Edinburgh, UK, 18th August, 2017.
What Keeps You Sharp? Show at the Edinburgh Festival Fringe as part of Edinburgh Beltane's Cabaret of Dangerous Ideas, Edinburgh, UK, 15th & 19th August 2017.
Year(s) Of Engagement Activity 2017
 
Description Edinburgh International Science Festival - Jenni Burton 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Invited to participate in 'Scientists have your data' at the Edinburgh International Science Festival, organised by the ADRC-Scotland, the Farr Institute and the Usher Institute University of Edinburgh. Public engagement event. Contribution to session as data scientist, discussing care home data linkage, Summerhall, 3/4/17. Project on care home data linkage voted by audience to have the most demonstrable public benefit.
Year(s) Of Engagement Activity 2017
 
Description Edinburgh International Science Festival 2014 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact CCACE held an interactive stall in the Museum of Scotland as part of the family drop-in activities at the Edinburgh International Science Festival 15th-19th April 2014. This was visited by over 2000 people over the course of the week, including Age UK's Chief Executive, Tom Wright. The stall and activities showcased the work of the Centre, particularly the Lothian Birth Cohort studies.

Children and parents were able to engage with many displays and objects relating to brain function and brain ageing. As in previous years many hundreds of people engaged with the Centre's representatives and illustrations of its work.
Year(s) Of Engagement Activity 2014
 
Description Edinburgh Speakers Festival - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact The new Edinburgh Speakers Festival 2016 took place from 9th-11th September and our own CCACE Director was invited to be part of this year's prestigious line-up. Speakers covered a large variety of topics including cognitive ageing, devolution, politics, history, literature, fashion, Islam, capitalism, cycling, RBS, the Lockerbie bombing, whisky and women's equality, but all with a focus on Scotland. Ian's talk was entitled "Understanding Healthy Cognitive Ageing: Scotland's Unique Contribution" and took place on Saturday 10th September.

This is what Ian said about the event:

"Well" said Disconnected Mind Director Ian Deary, "That's the first time I have been on the same bill as Ken Livingstone and Ruth Davisdson! What an ecclectic programme." Ian spoke on healthy cognitive ageing to an audience at the Edinburgh Speakers Festival. Of course, the LBC1936's results were highlighted, with a focus on the likely protective factors for cognitive ageing. "There was a middle-aged finalist from this year's Brain of Britain Radio 4 show in the audience", said Ian, "so that was a good basis from which to explain how crystallised ability ages pretty well." As usual,the photos of Mr Scott and his brain images went down well with the enthusiastic attendees.
Year(s) Of Engagement Activity 2016
URL http://www.ccace.ed.ac.uk/node/327
 
Description Evans - Brain Awareness Week schools workshop 2014 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Geographic Reach Local
Primary Audience Schools
Results and Impact Workshop for primary school children entitled "Who is the boss? How your brain runs your body" as part of the British Neuroscience Association's Brain Awareness Week, March 2014.

The children appeared very interested and engaged.
Year(s) Of Engagement Activity 2014
 
Description Explorathon - Museum of Scotland 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact The Centre was represented at Explorathon, an event at the Museum of Scotland held in September 2014. There were presentations about the human brain with a host of interactive objects and displays so that people understood about the brain function and ageing.

Interest and enthusiasm shown by members of the public at the event, including many young people, and increased awareness of the work of the Centre.
Year(s) Of Engagement Activity 2014
 
Description Faculty of Public Health Annual Scottish Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact This was a plenary invited keynote to the faculty of Public Health's annual conference. Professor Deary's talk was on healthy cognitive ageing, and he immediately followed and was heard by the Health Minister of the Scottish Government and her staff, as well as about 200 plus practitioners in public health. Therefore, it was a good opportunity to convey the work practitioners considering the important public health challenges for the Nation.
Year(s) Of Engagement Activity 2015
 
Description Frontiers BBC Radio 4 - LBC June 2014 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Results from the Lothian Birth Cohort studies were discussed by Ian Deary on BBC Radio 4's Frontiers programme, looking at the latest thinking about our brain power in old age. Robert Logie also discussed cognitive ageing on the programme.

The Lothian Birth Cohort studies were discussed alongside Cambridge studies and a provocative idea that there might be much less cognitive ageing than these studies suggest. As a result, there was discussion in the media, which reached the Centre, about the LBC studies.
Year(s) Of Engagement Activity 2014
 
Description Gow - INAPIC workshop, University of Zurich 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact Gow was invited to participate in a workshop entitled "Developmental Models of Brain-Behavior change relationships" held at the International Normal Aging and Plasticity Imaging Center, University of Zurich, on September 12-14 2013.

Expertise and research was shared amongst a group of eminent international speakers, including the INAPIC Advisory Board.
Year(s) Of Engagement Activity 2013
 
Description Gow - keynote Active Ageing conference Oct 2014 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Keynote presentation at Active Ageing conference, Hamilton, October 2014. This was attended by more than 150 professionals and brought together representatives from partner agencies and older adults alike.

The conference was reported through a variety of media channels, and many ideas and innovations were shared.
Year(s) Of Engagement Activity 2014
 
Description HMC conference - Stuart Ritchie 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact October 4 2016: gave a talk on intelligence generally, including LBC1936 data, to the HMC conference (audience: headteachers) in Stratford
Year(s) Of Engagement Activity 2016
 
Description HRH The Princes Royal 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Supporters
Results and Impact On the 6th July 2016 our University of Edinburgh Chancellor, HRH The Princess Royal, opened the new Centre for Dementia Prevention Building in the Bioquarter at Little France. The Centre for Dementia Prevention is led by Professor Craig Ritchie and aims to help society to understand what causes Dementia and then hopes to devise and implement strategies and lifestyle changes that will prevent Dementia from developing in the first place. CCACE was invited to this event as a complementary Centre working in ageing research at Edinburgh. Beverly Roberts represented CCACE at the opening in her role as Centre Scientific Administrator. After an initial tour of the new building, the Princes Royal was shown in to the reception marquee and introduced to a number of projects/Centres based at Edinburgh who work in both pathological and nonpathological ageing. When she was introduced to Beverly and CCACE, the Princes Royal showed great interest in the work of our members and asked why studying normal ageing was so important in the context of dementia. After the formal introductions there was an afternoon tea reception where Princess Anne was able to talk to some of the 120 invited guests. Beverly was very busy during this time speaking to lots of interested individuals wanting to know more about normal cognitive ageing.
Year(s) Of Engagement Activity 2016
URL http://www.ccace.ed.ac.uk/node/326
 
Description Healthy ageing - protecting your brain - Alan Gow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Presentation on factors related to brain health as part of the Spotlight on Science series at Exploration Day, Heriot-Watt University, Edinburgh, UK, 19th May 2018.
Year(s) Of Engagement Activity 2018
 
Description Healthy cognitive ageing - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Deary, I. J. (2016). Healthy cognitive ageing. University of the Third Age Science Group. Edinburgh UK, March.

Overview of general information on individual differences in human cognitive and brain ageing. Most examples taken from work on the Lothian Birth Cohorts of 1921 and 1936 and other cognitive ageing studies headed by Ian Deary at the University of Edinburgh. Followed by an extended question time raising additional points and ensuring understanding of the key messages.
Year(s) Of Engagement Activity 2016
 
Description Healthy cognitive ageing - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Deary, I. J. (2016). Healthy cognitive ageing. Iain Whyte House Group. North Queensferry, UK, February.

Overview of general information on individual differences in human cognitive and brain ageing. Most examples taken from work on the Lothian Birth Cohorts of 1921 and 1936 and other cognitive ageing studies headed by Ian Deary at the University of Edinburgh. Followed by an extended question time raising additional points and ensuring understanding of the key messages.
Year(s) Of Engagement Activity 2016
 
Description Healthy cognitive ageing and the Lothian Birth Cohorts of 1921 and 1936 - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Deary, I. J. (2016). Healthy cognitive ageing and the Lothian Birth Cohorts of 1921 and 1936. The Senior Fellows Club of the Royal Colleges of Physicians and Surgeons of Edinburgh. Edinburgh, UK, May.

Overview of general information on individual differences in human cognitive and brain ageing. Most examples taken from work on the Lothian Birth Cohorts of 1921 and 1936 and other cognitive ageing studies headed by Ian Deary at the University of Edinburgh. Followed by an extended question time raising additional points and ensuring understanding of the key messages.
Year(s) Of Engagement Activity 2016
 
Description Healthy cognitive ageing: findings from the Lothian Birth Cohorts - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Presentation to the Medico-Chirurgical Society of Edinburgh. Ian Deary summarised the Lothian Birth Cohorts studies and their many contributions to healthy cognitive ageing. This was followed by half an hour of questions and debate.
Year(s) Of Engagement Activity 2018
 
Description Hosting work experience pupils 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact CCACE hosted a series of work experience placements for pupils in s5/6 (secondary school). Pupils were given the opportunity to meet with CCACE members and observe some of the work of the Centre, including brain imaging, cognitive testing, and public engagement.

These placements were a great success, with several schools expressing an interest in sending pupils to the Centre for work experience in the future.
Year(s) Of Engagement Activity 2014
 
Description How to Age Well - Alan Gow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presentation on factors related to brain health as part of the Edinburgh Wellbeing Festival, Edinburgh, UK, 27th January 2019
Year(s) Of Engagement Activity 2019
 
Description How to Have a Better Brain - Gow 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Our former LBC Team member Dr Alan Gow (now at Heriot-Watt University), still actively engaged in LBC research, featured in the first episode of the new Radio 4 series 'How to have a better brain', presented by Sian Williams. The series aims to deliver a practical guide to boosting brain functioning throughout life with topics including sleep, diet, relaxation and exercise. The first episode focusses on the effect of exercise on brain function and in his interview, Alan draws on research evidence from the LBC1936. The episode and the associated online-only segment are available on the BBC iPlayer (http://www.bbc.co.uk/programmes/b065ssr8; http://www.bbc.co.uk/programmes/p02zz7ql)
Year(s) Of Engagement Activity 2016
URL http://www.bbc.co.uk/programmes/b065ssr8
 
Description Is learning languages good for your brain? - Thomas Bak 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Interactive invited talk about research on bilingualism and the brain at the "creative space", the Welcoming, Edinburgh. The session included drop-in activities in collaboration with Science Ceilidih and Leith Labs (in preparation for the Explorathon).
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/scienceceilidh/photos/a.1486421958282891/2187137418211338/?type=3
 
Description Language learning and brain health - Thomas Bak 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Webinar presentation for the Open University (collaboration with Lingo flamingo tutor training programme).
Year(s) Of Engagement Activity 2018
 
Description Language learning as a cognitive intervention - Thomas Bak 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited talk at the "Languages and Cultural knowledge in global healthcare" organised by QUB-AHRC
Year(s) Of Engagement Activity 2018
URL https://pure.qub.ac.uk/portal/en/impacts/languages-and-cultural-knowledge-in-global-healthcare(b94c1...
 
Description Learning a foreign language as a cognitive intervention in dementia - Thomas Bak 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Talk presented at the World Federation of Neurology, Viana do Castelo, Portugal.
Year(s) Of Engagement Activity 2018
URL https://www.spneurologia.com/evento/wfn-aphasia-dementia-and-cognitive-disorders-bienn/332
 
Description Leith Labs - Alan Gow 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact The Ageing Lab - Can taking up new activities improve the health and wellbeing of older adults? Workshop at Stay Sharp in Older Age hosted by Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE) in association with Leith Labs (part of The MRC Festival of Medical Research), Edinburgh, UK, 17th June 2017.
Year(s) Of Engagement Activity 2017
 
Description Life as a geneticist - Harris 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact A morning session talking to primary school children about life as a geneticist. The children made DNA models out of sweets and cocktail sticks (February 2016).
Year(s) Of Engagement Activity 2016
 
Description Lifetimes event at Midlothian Science Festival 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Discussion session about the history and current research relating to the Lothian Birth Cohorts, and a showing of the short film The Living Brainabout the Lothian Birth Cohorts. Followed by hands-on reaction time testing and demonstration of brain images/3D printouts.
~30 members of the public attended a talk and a Q and A session.

A great deal of interest in the Lothian Birth Cohort studies and multiple Q andA sessions with a very engaged audience.
Year(s) Of Engagement Activity 2014
URL http://midlothiansciencefestival.com/event/lifetimes/
 
Description Lothian Birth Cohort Study 1921 annual newsletter 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact The Lothian Birth Cohort Study 1921 has produced an annual newsletter since 2003. It was written to inform cohort study members of any main results from the study. The newsletter mailing list has a varied audience of lay and scientists. It summarises major achievements of the Centre and our recent news items.
Year(s) Of Engagement Activity Pre-2006,2006,2007,2008,
 
Description Lothian Birth Cohort Study 1936 annual newsletter 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact The Lothian Birth Cohort Study 1936 produces and annual newsletter which is sent to a large mailing list of over 500 individuals. Most of those on the mailing list are study members of the LBC cohort. The newsletter lets them know of new results which their data has produced. It is sent out with the study Christmas card.
Year(s) Of Engagement Activity Pre-2006,2006,2007,2008,
 
Description Lothian Birth Cohort reunion April 2014 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Participants in your research and patient groups
Results and Impact A reunion for participants in the Lothian Birth Cohorts of 1921 and 1936 was held on April 17th 2014 in Edinburgh. Presentations were given by main Principal Investigators and study co-ordinator on the results of the study to date, and short presentations were given on offshoot studies including the 6-Day Sample study and the MRC-funded Seniors USP study from which Dr Philippa Dall presented. There was also a premiere of the film "The Living Brain" made by Anne Milne.

Participants enjoyed the day and were interested and engaged in the information presented. They were given the opportunity to ask questions towards the end of the day and a great range of questions were received and answered. Talks from the reunion are on YouTube http://youtu.be/v1v7mHGkkgI
Year(s) Of Engagement Activity 2014
URL http://youtu.be/v1v7mHGkkgI
 
Description MRC Centenary celebrations - Dynamic Earth 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact CCACE had a stall at the Scottish MRC Centenary celebration held at Our Dynamic Earth on 19th November 2013.

Awareness of the work of the Centre was raised amongst attendees, who were largely other MRC-funded researchers.
Year(s) Of Engagement Activity 2013
 
Description MRC Festival of Medical Research 2016 - Brain Maze event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact In June 2016 CCACE opened its doors to the public for the second outing of our popular Brain Maze event. CCACE joined forces with the Centre for Regeneritive Medicine to put on the interactive open day event as part of the Medical Research Council's Festival of Medical Research.

The sell out event (around 50-60 people took part in some way) led people through the maze of corridors and rooms in the basement of the Department of Psychology, where CCACE is based. In each of the 11 rooms, the had 10 minutes to experience a different aspect of the ageing brain and body. Popular activities included a supermarket sweep game, shopping for the lifestyle factors which affect how our brain ages (like smoking) while busting a few myths (like the lack of effect of brain training). The Maze finished with a cafe where participants got the chance to speak with scientists and reflect on their experience of the Maze. One of the main comments was that, having spent 2 hours in the maze chatting to scientists, people would have liked more time in each room. A great endosement of the time and effort invested by CCACE and CRM staff and students.
Year(s) Of Engagement Activity 2016
URL http://www.ccace.ed.ac.uk/news-events/latest/maze2
 
Description MRC Scotland Showcase - Ian Deary, Andrew McIntosh, Matthew Iveson 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Policymakers/politicians
Results and Impact This was an event organised by the MRC to showcase their investments in health research in Scotland to Scottish Government officials. This involved manning a stand at the Scottish Parliament and talking about our research to guests. The primary audience was government officials and MSPs.
This took place on 06/02/2019

As well as describing our research we also discussed how our research could fit with current and upcoming government policy. We also handed out leaflets detailing 'policy asks'. The impact was primarily informing policy makers about current health research, but may have long-term impact as we follow-up connections made on the night.
Year(s) Of Engagement Activity 2019
 
Description MRC biomedical picture of the day Dec 2013 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact The brain tractography image from a Lothian Birth Cohort participant and created by Dr Mark Bastin from CCACE and the Brain Research Imaging Centre at the University of Edinburgh and Dave Liewald from CCACE was featured as the Biomedical Picture of the Day on the MRC's website on 11th December 2013.

This website is the portal into the Medical Research Council's work and is seen by thousands of people from all over the world, including members of the public and policymakers as well as academics and funders.
Year(s) Of Engagement Activity 2013
 
Description Mad Hatters Grey Matter, Cambo Estate 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact CCACE was represented with a stall and activities at the Mad Hatters Grey Matter event held at Cambo Estate on 18th July 2014. Around 50-100 people participated in the hands-on activities available at the stall.

From the audience reaction, we judged that family groups of various ages were engaged with ideas about brain function and brain ageing. We have been invited back to conduct an event concerning the Centre's work with the Lothian Birth Cohorts in the new year 2015 and have agreed to do so.
Year(s) Of Engagement Activity 2014
 
Description Media article - Sergio Della Sala 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Sergio Della Sala contributed to two media articles in 2013:
- Stamina, la vera scienza e tutta un'altra cosa (30th October 2013)
- Science facts, not fiction (17th September 2013)

These articles were available in the public domain.
Year(s) Of Engagement Activity 2013
 
Description Media coverage - alcohol consumption and change in cognitive ability 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Publication of an article by Centre members Alcohol consumption and lifetime change in cognitive ability: a gene-by-environment interaction study received coverage in the media in April 2014.

BPS Research Digest: http://digest.bps.org.uk/2014/04/alcohol-could-have-cognitive-benefits.html

The BPS Research Digest is seen by all members of the British Psychological Society. This is important because mild intake of alcohol is one of the proposed protective factors in cognitive ageing and it is important that the complexity of the data are understood by those who might be giving advice to older people.
Year(s) Of Engagement Activity 2014
 
Description Media coverage - speed of visual discrimination and ageing 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Publication of a paper by Centre members A strong link between speed of visual discrimination and cognitive ageing was covered in the media throughout August 2014.
Including:
BBC (http://www.bbc.co.uk/news/health-28639875)
Science Magazine (http://news.sciencemag.org/biology/2014/08/slow-visual-processing-may-lower-iq-we-age).


The radio and newspaper coverage of this raised a lot of awareness and discussion of the fact that simple processes to do with visual perception might underpin more complex thinking skills in older people. CCACE made a video to describe the findings: http://www.youtube.com/watch?v=vWkgP5sWCNA.
Year(s) Of Engagement Activity 2014
URL http://news.sciencemag.org/biology/2014/08/slow-visual-processing-may-lower-iq-we-age
 
Description Media coverage of EPSRC biomarkers for vascular dementia project, October 2014 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Publicity related to EPSRC biomarkers for vascular dementia project, October 27th 2014
Newspapers and online
o BBC News online (http://www.bbc.co.uk/news/uk-scotland-tayside-central-29758311)
o Guardian (http://www.theguardian.com/society/2014/oct/27/study-aims-to-spot-early-dementia-from-eye-exam)
o Times (https://www.thetimes.co.uk/tto/news/uk/scotland/article4248976.html)
o Daily Mail (http://www.dailymail.co.uk/health/article-2808897/Could-simple-eye-test-reveal-Alzheimer-s-Computer-software-analyses-changes-veins-arteries-spot-disease-early-stages.html?ITO=1490&ns_mchannel=rss&ns_campaign=1490)
o Daily Record
o Courier (http://www.thecourier.co.uk/news/health/eye-test-could-identify-alzheimer-s-1.648932)
o Scotsman (http://www.scotsman.com/news/health/eye-test-could-detect-early-stages-of-dementia-1-3584553)
o Herald (http://www.heraldscotland.com/news/home-news/viability-of-alzheimers-test-probed.25688100)
o Evening Telegraph (http://www.eveningtelegraph.co.uk/news/scotland/dundee-university-eye-test-could-identify-alzheimer-s-1.649011)
o STV News (http://news.stv.tv/east-central/297181-scottish-researchers-study-link-between-eye-tests-and-alzheimers/)
o Times of India (http://timesofindia.indiatimes.com/home/science/Eye-test-that-predicts-Alzheimers-years-before-its-symptoms-appear/articleshow/44947344.cms)
o OnMedica (http://www.onmedica.com/newsarticle.aspx?id=289fa059-e87c-46b3-abd4-2eaed1c470ff)
o Delhi Daily News (http://www.delhidailynews.com/news/Eye-test-to-predict-Alzheimers-years-before-its-appearance-1414410420/)
o E Canada Now (http://www.ecanadanow.com/health/2014/10/27/eye-tests-may-help-early-diagnose-alzheimers-disease/)
o Irish Independent (http://www.independent.ie/irish-news/health/eye-test-may-hold-the-key-to-detecting-alzheimers-30695237.html)
o Engineering & Technology magazine (http://eandt.theiet.org/news/2014/oct/alzheimers-software.cfm)
o Nursing Times (http://www.nursingtimes.net/nursing-practice/specialisms/neurology/simple-eye-test-could-speed-up-alzheimers-diagnosis/5076165.article)
o Huffington Post (http://www.huffingtonpost.co.uk/2014/10/27/alzheimers-disease-eye-test-_n_6052610.html)
o ITV News (http://www.itv.com/news/update/2014-10-27/eye-test-could-help-diagnose-alzheimers-disease/)

Television
o BCC Reporting Scotland
o STV News (http://player.stv.tv/programmes/news-at-six-dundee-tayside-full/)

Radio
o Wave 102
o Kingdom FM
o BBC Western Midlands
o BBC Gloucestershire
o BBC Herefordshire
o BBC 5Live
o BBC Radio Scotland Drivetime


There was considerable media coverage of this project, reaching a wide variety of public audiences.
Year(s) Of Engagement Activity 2014
 
Description Media interaction - Riccardo Marioni PLoS Genetics 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Feb 2017: Riccardo spoke to several national newspapers and international news agencies about his PLoS Genetics paper about the genetic prediction of male pattern baldness. The research was reported by the majority of the broadsheet and tabloid newspapers. He spoke about the paper on Radio Scotland's newsdrive show and on Radio New Zealand.
Year(s) Of Engagement Activity 2017
 
Description Media interest in research papers - Russ 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact 1. "Dr Tom Russ comments on risks of sub-clinical anxiety" - (The Times)

2. "Dementia study by Tom Russ lists everyday factors that may influence risk" Killin et al. (2016) BMC Geriatrics - (The Independent) (Daily Express) (Evening Times) (The Herald) (The Scotsman) (The Press and Journal) (Edinburgh Evening News) (The Scotsman) (Warwickshire Telegraph) (Derby Telegraph) (Sunday Mirror) (Daily Post) (The Chronicle) (Coventry Telegraph) (Adnkronos) (La Sicilia) (Liverpool Echo) (ANSA) (Web MD) (Panorama) (ABC) (Lavoz Digital) (The Times)

3. "Depressed people may have higher probability of dying from cancer, finds Dr Tom Russ" Batty et al. (2017) BMJ - (The Birmingham Mail) (The Daily Telegraph) (The Daily Mail) (i) (The Sun) (Metro) (The Herald) (The Scotsman) (The Yorkshire Post) (The National)
Year(s) Of Engagement Activity 2016
 
Description Media involvement - Michelle Luciano on diet and brain volume 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Live television interview on the BBC Breakfast Show (5th January; average of ~1.5 million viewers), 2 live radio broadcasts (BBC Reporting Scotland, BBC 3 Counties), 1 recorded TV interview (South Korean News Channel), 1 recorded radio interview (Radio Forth), many interviews for print media (e.g., New York Times, CNN, BBC, Reader's Digest, Brazilian Vogue) on my research on Diet and Brain Volume.
Year(s) Of Engagement Activity 2017
 
Description Morningside Justice and Peace Group 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact This invited talk and discussion was to a local group of mostly middle aged and older people who were interested to find out more about protective and risk factors for healthy cognitive ageing. There was opportunity for Professor Deary to present his research findings, and there was a long a lively discussion.
Year(s) Of Engagement Activity 2015
 
Description Multilingualism, ageing and MCI - Thomas Bak 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited "international speaker" talk at the Universidad Autonoma de Baja California, Mexico.
Year(s) Of Engagement Activity 2018
 
Description National Museum of Scotland LBC 3D brain 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact CCACE have been working with the National Museum of Scotland to develop a permanent exhibit in the museum based on a 3D printed brain of a Lothian Birth Cohort participant and an arresting laser etched crystal tractography model. The new exhibit was the subject of reports in the Scotsman and STV News. The exhibit is scheduled to go public in summer 2016.
Year(s) Of Engagement Activity 2016
 
Description National Museum of Scotland Science Saturday 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact October 2016: "Science Saturday" event at the National Museums of Scotland showcases gene science and the impact and relevance of our research to human health and society.

The Science Saturday event was open to all, with a mini-symposium and debate session, in addition to a Market Place event held in the main hall area. Stands representing the Institute of Genetics and Molecular Medicine, the MRC Centre for Cognitive Ageing and Cognitive Epidemiology, Generation Scotland, the Wellcome Trust Clinical Research Facility Genetics Core, Edinburgh Genomics, the Usher Institute, the Mason Institute for medicine, life-sciences and the law, the Institute for the study of Science, Technology and Innovation and the MRC Farr, Edinburgh all set up shop to describe their take on gene science and the impact and relevance to human health and society.

The talk and exhibition sparked questions and discussion afterwards.
Year(s) Of Engagement Activity 2016
URL http://www.ed.ac.uk/centre-genomic-medicine/news-events/news-2016/science-saturday
 
Description National Museum of Scotland exhibition - LBC1936 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact From 8 July 2016, the National Museum of Scotland (Edinburgh) have unveiled a new exhibit, John Scott's brain.

LBC1936 participant, Mr John Scott saw his brain for the first time in January this year at the National Museum of Scotland's Collections Care Centre. STV and the LBC team were there to witness Mr Scott seeing a 3D print of his living brain, taken from MRI data captured as part of the Lothian Birth Cohort 1936 (LBC1936) study. The 3D print will go on display in the museum from 8 July 2016, along with a stunning representation of Mr Scott's white matter (tractography) etched in crystal glass. When asked how he felt about having his brain on display in the National Museum, Mr Scott said "It's great, I told my grandchildren, when I'm not here, you can go and see my brain!"


You can hear Mr Scott talking about his experience on STV News (from 15:30) at http://player.stv.tv/episode/36pt/news-at-six-edinburgh-east-full/thu-07-jan-6-00-pm/

Dr Simon Cox, MRC Imaging Fellow on the LBC1936 study, said "I am used to looking at brain images on the computer day-to-day, but seeing a real model of the brain's white matter connections in glass and the outer surface of the brain like this is a unique experience - they are incredibly striking objects".

The brain imaging in LBC1936 is overseen by CCACE Group Leaders Professor Joanna Wardlaw and Dr Mark Bastin of Edinburgh Imaging and suported by funding from Age UK and the MRC. The 3D models of the brain surface and white matter were developed by Dr Mark Bastin and Dave Liewald in collaboration with Sophie Goggins, Assistant Curator of Biomedicine at the National Museum of Scotland and the Edinburgh College of Art (3D printed model).

You can learn more about the exhibit and Mr Scott in an NMS blog by Sophie Goggins http://blog.nms.ac.uk/2016/01/08/the-lothian-birth-cohort-medical-imaging-in-our-new-galleries/
Year(s) Of Engagement Activity 2016
URL http://blog.nms.ac.uk/2016/01/08/the-lothian-birth-cohort-medical-imaging-in-our-new-galleries/
 
Description Neuropsychological evaluation & cognitive ageing - Thomas Bak 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Invited "international speaker" talk at the Universidad Autonoma de Baja California, Mexico.
Year(s) Of Engagement Activity 2018
 
Description New Scientist article - David Hill 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact New Scientist piece on DNA and intelligence
Year(s) Of Engagement Activity 2018
URL https://www.newscientist.com/article/2163484-found-more-than-500-genes-that-are-linked-to-intelligen...
 
Description Paterson Della Sala - curriculum for excellence Scotland on Sunday 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Lindsay Paterson and Sergio Della Sala commented on the curriculum for excellence in Scotland on Sunday, 11th August 2013.

This article was in the public domain.
Year(s) Of Engagement Activity 2013
 
Description Penicuik University of the Third Age - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Penicuik U3A discuss healthy cognitive ageing
"It's always a good sign when they have to put out extra chairs," said Ian Deary, after his talk on 16th February to Penicuik's branch of the University of the Third Age. "They said they usually get 30-50 people, but I lost count after 60. It's great to see such enthusiasm for hearing about healthy cognitive ageing and the Lothian Birth Cohorts' contribution to that. I encouraged people in the audience to ask any questions as we went along, and they were good at that. However, there were lots more excellent questions and discussions at the end of the talk. They wanted to know the evidence about many things, including genetics, dementia, physical exercise, smoking, sleep and cognitive engagement. I was especially pleased, when I was having my tea and custard cream afterwards, when an audience member congratulated my team on demonstrating reverse causation for some potential factors in cognitive ageing!" We note that Ian cycled to and from Penicuik to give the talk, which we hope contributed a little towards keeping him sharp.
Year(s) Of Engagement Activity 2017
URL http://www.ccace.ed.ac.uk/node/342
 
Description Personality stability research paper - Harris 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact The paper Harris MA, Brett CE, Johnson W, Deary IJ. Personality stability from age 14 to age 77 years. Psychol Aging. 2016;31(8):862-874 received considerable press interest in February 2017. It sparked debate among the media and was featured here:

The Times, 20th Feb
http://www.thetimes.co.uk/article/life-changes-you-60-year-study-finds-vbdzcp5j6

The Daily Mail, 20th Feb
http://www.dailymail.co.uk/sciencetech/article-4241782/You-different-14-77-says-personality-study.html

De Morgen, 21st Feb
http://www.demorgen.be/wetenschap/uw-karakter-ligt-niet-vast-b8f90f63/

Huffington Post, 22nd Feb
http://www.huffingtonpost.com/entry/personality-changes-age_us_58ac6736e4b02a1e7dac16b3
Year(s) Of Engagement Activity 2017
URL http://www.thetimes.co.uk/article/life-changes-you-60-year-study-finds-vbdzcp5j6
 
Description PhD retreat at Firbush field centre, 2014 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact The CCACE PhD students and CCACE-affiliated PhD students spent 3 days at the University of Edinburgh's field centre, Firbush, on Loch Tay. there was a packed programme of outdoor activities, academic/training/development work and discussions, and social events. CCACE postdoctoral students contributed to some of the discussions.

This was an excellent event for building the cohort of PhD students who are focussing on cognitive and brain ageing. It means that there will be greater sharing of expertise and discussion of shared aims and methodologies.
Year(s) Of Engagement Activity 2014
 
Description Press release - David Hill 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Press release sent widely to coincide with a publication in Molecular Psychiatry. This was picked up very widely in tabloid, broadsheet, online and international press.
Year(s) Of Engagement Activity 2018
URL https://www.ed.ac.uk/news/2018/hundreds-of-genes-linked-to-intelligence-in-global
 
Description Press release - UK Dementia Platform launch 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact The launch of the UK Dementia Platform, with which several CCACE members are involved, was marked by a press release on the University of Edinburgh's website (http://www.ed.ac.uk/news/2014/dementia-190614), and an accompanying You Tube video (http://youtu.be/xyer_t-X3lQ >). To date (November 2014) the video has had 80 views.

The UK Dementia Platform has had a great deal of press associated with its launch. This is an important opportunity to showcase the work of CCACE and its members.
Year(s) Of Engagement Activity 2014
 
Description Press release - genes linked to dementia - Riccardo Marioni 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Press release of publications finding received widespread press coverage. Carried out a live interview with BBC Radio to discuss my study that identified 3 new genes associated with Alzheimer's disease (May 2018).
Year(s) Of Engagement Activity 2018
 
Description Professor Sir Godfrey Thomson exhibition 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact A treasure trove of artefacts relating to this pioneering educational psychologist will be displayed at the Univeristy of Edinburgh from Friday 29th July until 29th October. Entrance to the exhibition is free, and it is open to the public.

Piles of intriguing ledgers and personal mementos will feature in an exhibition reconstructing the life and work of Professor Sir Godfrey Thomson. Sir Godfrey - who led the world's only nationwide IQ tests, in Scotland - was an innovative educator who firmly belived that educational opportunity should not be linked to social staus. From the 1920s onwards he advocated comprehensive education. Thomson was based at the Moray House School of Education, now part of the University of Edinburgh. His greatest legacy for today's researchers was to test the intelligence of almost every Scottish 11-year-old child in 1932, and again in 1947.

For the first time, the Scottish Mental Survey's unique ledgers will go on public view, with a selection of sample pages on show. The ledgers hold the world's only record of IQ-type scores from full national year-of-birth cohorts.

Sir Godfrey's findings have formed the basis of much of the cutting-edge research at the University of Edinburgh since the late 1990's into how the brain ages, led by Professor Ian Deary. His team studies the now-older people who took part in the Scottish Mental Surveys.

Ian has spent the past decade investigating Sir Godfrey's life, and in 2008 he rescued a mass of never-before-seen documents and objects from Thomson's family home in Edinburgh, just before it was demolished. A selection of those artefacts, portraits and documents feature in the exhibition, telling the story of who Sir Godfrey was and what his motivations were.

Ian Deary said: "Godfrey Thomson saw mental ability tests as an imperfect but useful means to give poor children a chance in life. He was determined to look past pupils' social status, and try to see their underlying ability. By all accounts he was modest, not motivated by money, and happy to share academic wins, which in part led him to fade from the history books. I'm delighted we are now able better to understand and evaluate the pioneering work of this multi-talented and elusive man."

8103 individuals visited the exhibition.
Year(s) Of Engagement Activity 2016
URL http://www.bbc.co.uk/news/uk-scotland-edinburgh-east-fife-36894717
 
Description Public lecture series (Yau) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Scientists conducting new research at the University of Edinburgh share their latest work in the annual series, Let's Talk About Health: Understanding Disease. The talks took place between December 2015 and March 2016. Centre member, Yau, gave a talk entitled: "Delirium and Dementia in old age: do our stress hormones contribute?". The talk sparked questions and discussion afterwards.
Year(s) Of Engagement Activity 2016
URL http://www.ed.ac.uk/news/2015/healthtalks
 
Description Public panel engagement (mental health across the life course) - Matthew Iveson 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Study participants or study members
Results and Impact This involved presentations made to two public panels; the Administrative Data Research Centre Scotland Public Panel and the Mental Health Data Science Scotland Stakeholder Advisory Group.
The primary audience was the general public. There were roughly 8 people in attendance at each event, though the slides and summary have also been disseminated across the panel members who couldn't attend. The intended reach was local.

Dates: 12/10/2018 and 06/02/2019

The activity was aimed at presenting a planned study for linking mental health data for the Scottish Mental Survey 1947 cohort of individuals, and gauging public opinion on this study. We also wanted to invite feedback on the study design and its planned engagement work.

The output was evidence of support for our research which can be used in research governance applications. Feedback has also helped us design a public engagement strategy, including working with suggested third sector organisations to impact policy.
Year(s) Of Engagement Activity 2018
 
Description QMRI Administrators Forum 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Professor Deary gave a talk on his research on human cognitive ageing to the senior administrative staff of various units in the University of Edinburgh's College of Medicine and Veterinary Medicine. It was a good opportunity to spread the word about the research to a group at the University who is neither academic nor student, but are important in helping the process of research to flow easily.
Year(s) Of Engagement Activity 2015
 
Description Research the Headlines 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Gow is contributor and co-chair of the RSE Young Academy of Scotland's "Research the Headlines" blog, offering contributions featuring research from psychology, gerontology, neuroscience and health.

The blog has 88 followers and is publicised through Twitter, Facebook and other social media channels.
Year(s) Of Engagement Activity 2012,2013,2014
URL http://researchtheheadlines.org/
 
Description Research the Headlines - Alan Gow 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Research the Headlines - addressing the way research is portrayed in the media and launch plans for Rewrite the Headlines. Presentation at the Beltane Twilight: Media Liaison. Edinburgh UK, 27th May 2015.

Contributor (and Co-Chair) to the RSE Young Academy of Scotland's "Research the Headlines" blog. My contributions feature research from psychology, gerontology, neuroscience and health.
Year(s) Of Engagement Activity 2015
 
Description Resilience Ceilidh 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact CCACE researchers worked with community groups (Harmony Choir and Leith Scottish Women's Institute) to produce creative pieces, inspired by the concept of 'resilience'. In celebration of their efforts, a 'Resilience Ceilidh' was held on 3rd February 2018, where the groups shared their creative works with their families, friends and the public. The event provided an opportunity to find out more about research into resilience at CCACE.
Year(s) Of Engagement Activity 2018
URL http://www.ccace.ed.ac.uk/sites/default/files/CCACE%20Notes%20-%20Lifelong%20Resilience.pdf
 
Description Rewrite the Headlines: Engaging young people in evaluating research in the media (Gow) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The exhibit, "Rewrite the Headlines: Engaging young people in evaluating research in the media", was displayed at the British Academy Soiree, London, UK, 28th June 2016. The exhibit sparked questions and discussion on how research is portrayed in the media.
Year(s) Of Engagement Activity 2016
URL http://www.britac.ac.uk/rewrite-headlines-helping-young-people-evaluate-how-academic-research-report...
 
Description Ritchie & Marioni - Royal Statistical Society Edinburgh Lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Stuart Ritchie and Riccardo Marioni described new findings from analyses of the Lothian Birth Cohorts to over 60 members of the Royal Statistical Society - Edinburgh Group. Following the lecture there was a detailed question & answer section.
Year(s) Of Engagement Activity 2016
 
Description Ritchie - "More Or Less" on BBC World Service 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Stuart Ritchie was included as an expert on the radio programme "More Or Less" on the BBC World Service.
Year(s) Of Engagement Activity 2015
 
Description Ritchie - APS 2015 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Stuart Ritchie presented recent work on neuroimaging and cognitive abilities as part of a symposium at the May 2015 Association for Psychological Science Convention in New York City. The talk was standing room only, with over 50 people in attendance.
Year(s) Of Engagement Activity 2015
 
Description Ritchie - Bringing Up Britain on BBC Radio 4 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Stuart Ritchie joined a panel discussion on BBC Radio 4's programme "Bringing Up Britain" to discuss research in cognitive development and genetics. Feedback was received by email and was very positive.
Year(s) Of Engagement Activity 2015
 
Description Ritchie - Columbia University 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact Stuart Ritchie presented work on cognitive ageing in the Lothian Birth Cohort to a group of psychology postdoctoral researchers and postgraduate students at the Psychology Department of Columbia University.
Year(s) Of Engagement Activity 2015
 
Description Ritchie - Conference on Ageing and Cognition 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Stuart Ritchie presented research from the Lothian Birth Cohort 1936 at the Third International Conference on Ageing and Cognition, held in Dortmund, Germany. The talk attracted an audience of over 50 scientists and postgraduate students.
Year(s) Of Engagement Activity 2015
 
Description Ritchie - Empirical Sex talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Stuart Ritchie gave a talk on sex differences in cognitive abilities for the Empirical Sex series of lectures, based in London, to an audience of around 60 paying members of the general public. The talk included data from the Scottish Mental Surveys, the basis of the Lothian Birth Cohort studies. It was followed by an hour-long question and answer session.
Year(s) Of Engagement Activity 2016
 
Description Ritchie - Gifford Society Talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact A public presentation at the general interest group The Gifford Society on the history of the Lothian Birth Cohorts, the major findings from our research, and cognitive ageing in general. Sparked a long and interesting question&answer session.
Year(s) Of Engagement Activity 2016
 
Description Ritchie - Glasgow Geriatrics Society 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Stuart Ritchie presented findings from the Lothian Birth Cohort 1936 at a meeting of the Glasgow Geriatrics Society, a group of medical practitioners based in the Glasgow Royal Infirmary.
Year(s) Of Engagement Activity 2015
 
Description Ritchie - Good Morning Scotland, August 2014 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact Centre member Stuart Ritchie was interviewed on BBC Scotland's programme Good Morning Scotland; on 6th August 2014. In the interview, he discussed his recent publication A strong link between speed of visual discrimination and cognitive ageing. This was also covered in many newspapers.

The radio and newspaper coverage of this raised a lot of awareness and discussion of the fact that simple processes to do with visual perception might underpin more complex thinking skills in older people.
Year(s) Of Engagement Activity 2014
 
Description Ritchie - ISIR 2015 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Stuart Ritchie gave a talk at the International Society for Intelligence Research 2015 conference, held in Albuquerque, New Mexico, on polygenic risk for schizophrenia and cognitive decline in the Lothian Birth Cohort studies.
Year(s) Of Engagement Activity 2015
 
Description Ritchie - Infinite Monkey Cage, August 2014 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Centre member Stuart Ritchie participated as a panelist on BBC Radio 4's Infinite Monkey Cage programme, broadcast on 11 August 2014. In this, Ritchie discussed the nature, causes and consequences of people's intelligence differences, showcasing the work of the Centre and discussing causes of people's differences in cognitive ageing.

This programme has a large audience and the Centre's work on cognitive abilities and cognitive ageing will have been heard by a large number of people.
Year(s) Of Engagement Activity 2014
 
Description Ritchie - ResearchEd Conference Lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Stuart Ritchie presented a talk on intelligence and cognitive ability research at the "ResearchED" 2015 conference in London. This conference is attended by teachers from across the UK with an interest in evidence-based education. The talk, which focused on the evidence surrounding the causes and consequences of differences in cognitive abilities, was attended by around 40 audience members.
Year(s) Of Engagement Activity 2015
 
Description Ritchie - School Visit (Davidson's Mains Primary) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Workshop for two classes of Primary School children (around 50 in total) for Brain Awareness Week. Involved a variety of activities for learning about the brain, and answering questions from the children about neuroscience. Feedback from the school was very positive.
Year(s) Of Engagement Activity 2015
 
Description Ritchie - Talk Radio Europe 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Stuart Ritchie was interviewed about CCACE research on UK Biobank on the Spain-based radio station Talk Radio Europe.
Year(s) Of Engagement Activity 2016
 
Description Ritchie - University of Munster 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Stuart Ritchie gave a presentation on recent results from the Lothian Birth Cohort 1936 to the Psychology Department at the University of Munster, Germany. The talk was attended by around 40 Psychology Department staff and students.
Year(s) Of Engagement Activity 2015
 
Description Ritchie - Victoria Hospital Lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Stuart Ritchie talked as part of a lecture series at the Victoria Hospital in Kirkcaldy, Fife, to an audience of around 25 medical professionals from across Fife. He discussed recent results from the Lothian Birth Cohort 1936 on brain imaging and genetics.
Year(s) Of Engagement Activity 2016
 
Description Roberts - PhD Autumn Training School 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact In 2012, 2013 and 2014 the CCACE Scientific Administrator collaborated with Edinburgh Neuroscience to run an extremely successful PhD training school. The day long workshop was set up to introduce current PhD students to topics such as "writing up your research", "where to get funding after your PhD", "how to give a good presentation". Across the two years the workshop has been attended by around 100 PhD students. Several senior staff in CCACE and beyond took part, including a talk and panel discussion from the CCACE Director.

PhD students are now more confident in their research skills and have a better understanding of the options available to them once they have completed their studies. This includes new skills in grant application and fellowship application.
Year(s) Of Engagement Activity 2012,2013,2014
URL http://www.edinburghneuroscience.ed.ac.uk/autumnschool/2013/index.html
 
Description STV Coverage - NMS Exhibit LBC Brain 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact CCACE researchers and core staff collaborated with National Museums of Scotland to create a 3D cortical model and 3D glass etching of the white matter of an LBC1936 participant. This will be part of a new exhibition in the National Museum of Scotland this year - STV covered this story for their Evening News on 7th January 2016.
Year(s) Of Engagement Activity 2016
 
Description STV coverage - LBC reunion 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Media (as a channel to the public)
Results and Impact The LBC reunion, organised and facilitated by CCACE, was covered on STV news on 17th April 2014.

XXX
Year(s) Of Engagement Activity 2014
 
Description Science Festival participation - Riccardo Marioni 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Participation and stall design for Edinburgh Science Festival (Apr 2018). Many people (20+) learned about DNA methylation for the first time at this event.
Year(s) Of Engagement Activity 2018
 
Description Science Magazine article 31st October 2014 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact The work of the Centre, in particular the Lothian Birth Cohorts, was featured in a 4-page article in Science Magazine by Emily Underwood. This was published on 31st October 2014 and promoted through various social media outlets.

It is very unusual to have the world's top general science journal devote four pages to a single set of studies, i.e. our Lothian Birth Cohort studies. The prominence of this story meant that we obtained large numbers of national and international contacts indicating that they had seen and enjoyed the report, and wanted to know more about the studies.
Year(s) Of Engagement Activity 2014
URL http://www.sciencemag.org/content/346/6209/568.summary
 
Description Science Saturday, National Museum of Scotland 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Designed and ran the stand at the "Should we sequence everyone's genome from birth?" Science Saturday public event at National Museum Scotland. Sat 15th October 2017.
Year(s) Of Engagement Activity 2017
 
Description Scottish Education Policy Lecture - Lindsay Paterson 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Paterson, L. (2018), 'Scottish Education Policy: Why Statistics Matter', lecture in honour of Professor David Raffe, Edinburgh University, 26 March

Audience: mainly local academic audience, but also some researchers in Scottish Government.

Impact: Informal feedback suggested that it helped persuade some government researchers that survey research in education is valuable. This was picked up by the Royal Society of Edinburgh in their submission to the inquiry by the Scottish Parliament Education and Skills Committee into national assessments in schools. At the public evidence session at which Keir Bloomer (from the RSE) and Prof Paterson spoke, they stressed the importance of education surveys, and Prof Paterson's comments referred back to the SCRE surveys of 1932 and 1947 (upon which the LBC is based). The report of the Committee will appear this Spring.

The parliamentary evidence session at which this was discussed was on 23 January 2019.
Year(s) Of Engagement Activity 2018
URL https://media.ed.ac.uk/media/Professor+Lindsay+Paterson+%7C+Scottish+Education+Policy+A+why+statisti...
 
Description Scottish Older People's Assembly 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact CCACE had an exhibition stand at the Scottish Older People's Assembly, which took place on 11th December 2013. As well as information about the Centre, copies of Age UK's 'Improving Later Life' publications were given out.

The work of the CCACE on cognitive and other aspects of ageing reached a wide group of lay older people and raised awareness of the contributors to healthy cognitive ageing.
Year(s) Of Engagement Activity 2013
 
Description Staying Sharp - Alan Gow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presentation on factors related to brain health as part of "Ageing: From cells to Cognition" at the Pint of Science Festival, Edinburgh, UK, 14th May 2018.
Year(s) Of Engagement Activity 2018
 
Description Staying Sharp - Alan Gow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Presentation on factors related to brain health as part of Doors Open Day, the Royal Society of Edinburgh, Edinburgh, UK, 29th September 2018
Year(s) Of Engagement Activity 2018
 
Description Staying Sharp webpages refresh 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Age UK Staying Sharp webpages, which provide a plain-language guide on the latest cognitive ageing research, were refreshed with the aim of increasing public engagement. The refresh was conducted in consultation with CCACE staff and includes a new quiz on brain health, developed in collaboration with Alan Gow.
Year(s) Of Engagement Activity 2019
URL https://www.ageuk.org.uk/information-advice/health-wellbeing/mind-body/staying-sharp/how-well-do-you...
 
Description Staying Sharp website - Age UK collaboration 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact In collaboration with Age UK, CCACE contributed to the design of a new website known as Staying Sharp. This provided advice to the general public on how to stay mentally sharp in later life. It was based on 10 "Top Tips" from academic experts. Each wrote a short summary on their expert subject for the website. CCACE's Director, Professor Ian Deary, also provided a voice over for an accompanying cartoon film on the "Top Tips". This can also be found on the website. This summary of research was based partly on published research on the Lothian Birth Cohort 1936 and weighs up the existing evidence on alcohol and caffeine consumption and cognitive ageing. In order to extend the reach and impact of the Staying Sharp web pages, the summary also appears in an A5-printed booklet which will be advertised via inserts in selected newspapers and magazines, inviting people to contact Age UK for a free copy.
"Staying sharp - what you need to know about brain ageing
Staying Sharp is a new 'one-stop-shop' on the Age UK website where you can find out what you need to know about thinking skills in later life.
Staying Sharp summarises ground-breaking research findings and information from leading researchers and the Global Council on Brain Health on the key lifestyle factors that affect how your brain ages.
Staying Sharp has been developed in partnership with the Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE) at the University of Edinburgh."
Find out more at Staying Sharp http://bit.ly/stayingsharpnews
Year(s) Of Engagement Activity 2017
URL http://www.ageuk.org.uk/health-wellbeing/staying-sharp/
 
Description Staying sharp in later life; your expert guide to ageing well 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact 'Staying sharp in later life' is a plain-language guide developed by Age UK in collaboration with researchers at CCACE . It provides accessible summaries of the latest research on a range of subjects from exercise and brain training, to diet, smoking and alcohol. There is a print and online version of the guide.
Year(s) Of Engagement Activity 2015,2018
URL https://www.ageuk.org.uk/information-advice/health-wellbeing/mind-body/staying-sharp/
 
Description Sunday Morning With... the LBC1936 - Ian Deary 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The Lothian Birth Cohort 1936 (LBC1936) got a good airing on BBC Radio Scotland on Sunday 26th February 2017. LBC1936 participant Margaret Macintosh and Study Director Ian Deary were interviewed by presenter Cathy MacDonald on the programme Sunday Morning With... "Cathy MacDonald was clearly very taken with the uniqueness and long-term nature of the LBC1936 sample and the importance and range of the findings", said Ian, "and so a piece that was planned to be 5-10 minutes long ran for about 20 minutes. It was great to hear Margaret's enthusiasm for the project, her reflections on what we do, and what we might add to the study." The radio piece was stimulated by the front-page article in The Times on 21st February 2017 which discussed the study on personality stability that was conducted on the LBC1936's sister study, the 6-Day Sample.
Year(s) Of Engagement Activity 2017
URL http://www.bbc.co.uk/programmes/b08g5h5s#play
 
Description Talk at Edinburgh College on the Genetics of Happiness - Michelle Luciano 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Talk to students, mainly high school pupils studying Psychology. The feedback from the talk was that it broadened the students' understanding of what Psychology involves as the talk emphasised biological determinants of behaviour. It sparked a change in attitudes to what Psychology entailed as a discipline. One student noted that she is now considering studying Psychology at University.
Year(s) Of Engagement Activity 2018
 
Description Talk at cohort event - Riccardo Marioni 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Study participants or study members
Results and Impact Participation at research communication/reunion event for >400 cohort members of Generation Scotland and the Lothian Birth Cohorts (June 2018)
Year(s) Of Engagement Activity 2018
 
Description Talk to high school students - Riccardo Marioni 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact • Alzheimer's research communication to two final-year high school students preparing projects on genetics (June and Oct 2018).
Year(s) Of Engagement Activity 2018
 
Description Ten (quite) interesting things about intelligence - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact Presentation about intelligence differences to the University of the Third Age Science Group.
Year(s) Of Engagement Activity 2018
 
Description The 6-Day Sample Study annual newsletter 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact This annual newsletter from the 6-Day Sample Study is sent out with the study Christmas card. It details the main highlights from the study over the past year and any new findings which have arisen from the data collected.
Year(s) Of Engagement Activity 2014,2015
 
Description The Brain is wider than the sky exhibition 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The brain tractography image from a Lothian Birth Cohort participant and created by Dr Mark Bastin from CCACE and the Brain Research Imaging Centre at the University of Edinburgh and Dave Liewald from CCACE was featured at an outdoor exhibition of brain images in St. Andrews Square, Edinburgh called: 'The Brain - is wider than the sky'. This exhibition was curated by researchers from the University's Patrick Wild Centre for Research into Autism, Fragile X Syndrome and Intellectual Disabilities in partnership with the Scottish charity Mindroom.

The exhibition showcased world-leading research by Edinburgh University and it was an honour for the work of CCACE to be featured. It was on display in a prominent location in central Edinburgh from 7th June to 4th July 2014 from 8am to 8pm and was seen by thousands of people.
Year(s) Of Engagement Activity 2014
 
Description The BrainBox 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact CCACE has developed a new workshop for school age children, based on the new 'BrainBox' (@brainboxone), developed with £5,000 funding from the Medical Research Council. A workshop titled "What's in the BrainBox?" was presented at the Edinburgh International Science Festival to 70 children aged 8-12 years old (and their parents!). This has also been delivered to a Beaver Scout troupe and will be repeated in this year's science festival.
Year(s) Of Engagement Activity 2015
 
Description The Disconnected Mind quarterly newsletter 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The Disconnected Mind newsletter is sent out quarterly to a mailing list of over 100 people. This details main results and highlights from the study.
Year(s) Of Engagement Activity 2008,2009,2010,2011,2012
 
Description The Disconnected Mind: An Update. Age UK Headquarters - Simon Cox 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Third sector organisations
Results and Impact Simon Cox met with the Research Team at Age UK to update them on new findings and discuss areas of mutual interest in ongoing and future plans for the study.
Year(s) Of Engagement Activity 2018
 
Description The Disconnected Mind: Technical Workshop. Reinsurance Group of America - Simon Cox 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact A technical workshop for the analysts at the UK offices of the Reinsurance Group of America; of particular interest was the work on polygenic risk scores and their ability to predict important outcomes of interest (including mortality) with increasing accuracy as sample sizes increase.
Year(s) Of Engagement Activity 2018
 
Description The Great British Brain Off (Gow) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Originally presented as part of the Cabaret of Dangerous Ideas by the Beltane Public Engagement Network, a platform that offers engagement between academics, researchers and the public on a range of different scientific topics, The Great British Brain Off looks at the way in which you can help your brain remain active and alert at any age. Part discussion, part interaction and part debate, this particular event is presented by Dr Alan Gow and compered by Susan Morrison. Dr Gow has presented this event on numerous occasions: Living Well in Later Life Conference, Hamilton, UK, 2nd December 2016, British Science Festival, Swansea, UK, 8th September 2016, Irvine Bay's Talk Science programme, jointly hosted by the Royal Society of Edinburgh, Irvine, UK, 21st April 2016. The talk sparked questions and discussion afterwards.
Year(s) Of Engagement Activity 2016
URL https://edinburghfestival.list.co.uk/event/512537-the-great-british-brain-off/
 
Description The Great British Brain Off - Alan Gow 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact The Great British Brain Off. Show at the Edinburgh Festival Fringe as part of Edinburgh Beltane's Cabaret of Dangerous Ideas, Edinburgh, UK, 27th August 2015.
Year(s) Of Engagement Activity 2015
 
Description The Great British Brain Off - Gow 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact For the second year in succession, Dr Alan Gow joined forces with compere Susan Morrison and the Cabaret of Dangerous Ideas (from the Beltane Public Engagement Network) to put on a CCACE-sponsored show at this year's Edinburgh Festival Fringe. The Great British Brain Off offered an hour of lively, engaging, interactive debate, which examined the various ingredients that might protect (or harm) the ageing brain, much of it gleaned from the Disconnected Mind project. Lifestyle factors discussed included physical activity, diet and smoking, with the audience determining what was explored in detail. To promote the show, a trailer was produced which was viewed over 2,000 times between the CCACE YouTube channel and Age Scotland's Facebook page. The show was rated 4* by the Edinburgh Spotlight (http://www.edinburghspotlight.com/2015/08/review-the-great-british-brain-off/).
YouTube trailer can be watched here: https://www.youtube.com/watch?v=X20p9oCYI8Y
Year(s) Of Engagement Activity 2015
URL https://www.youtube.com/watch?v=X20p9oCYI8Y
 
Description The Scottish Mental Surveys and the Lothian Birth Cohorts - Judy Okely 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presentation on factors related to healthy cognitive ageing to around 15 members of the Edinburgh Electrical Engineering Society, October 2018.
Year(s) Of Engagement Activity 2017,2018
 
Description The rescue of Sir Godfrey Thomson - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Deary, I. J. (2016). The rescue of Godfrey Thomson. University of Edinburgh Centre for Research Collections. Edinburgh, UK, August.

This illustrated talk described the findings of the Godfrey Thomson archives, their formal cataloging, and the exhibition based on them that was curated by Ian Deary. Also covered, were the academic publications written based on the archival materials.
Year(s) Of Engagement Activity 2016
URL https://www.youtube.com/watch?v=ZObidTDX4lI
 
Description Twitter - CCACE 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Twitter.com/ccace has 460 followers and the account has tweeted 562 times.
Year(s) Of Engagement Activity 2010,2011,2012,2013,2014
URL http://www.twitter.com/ccace
 
Description Understading the causes, consequences, and facets of neuroticism - Ian Deary 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Presentation 'Understanding the causes, consequences, and facets of neuroticism' at the Wellcome STRADL Scientific Advisory Board meeting. Edinburgh, UK, October, 2018.
Year(s) Of Engagement Activity 2018
URL https://www.eventbrite.co.uk/e/wellcome-trust-stradl-award-annual-scientific-meeting-tickets-5059148...
 
Description What Keeps Us Sharp? - Alan Gow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Third sector organisations
Results and Impact Presentation on factors related to brain health at the Age Scotland Edinburgh and Lothians Meeting of Older People's Groups and Organisations, Edinburgh, UK, 6th November 2018
Year(s) Of Engagement Activity 2018
 
Description What Keeps You Sharp? - Alan Gow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presentation on factors related to brain health as part of Brainworks Day (part of the Engaging Libraries project, funded by the Carnegie Trust and the Wellcome Trust), Kirkintilloch, UK, 28th April 2018.
Year(s) Of Engagement Activity 2018
 
Description What Keeps You Sharp? - Alan Gow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Show about factors related to brain health at the Edinburgh Festival Fringe as part of Edinburgh Beltane's Cabaret of Dangerous Ideas, Edinburgh, UK, 7th & 16th August 2018.
Year(s) Of Engagement Activity 2018
 
Description What Keeps You Sharp? - Alan Gow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Show on factors related to brain health at Go Live! At the Green as part of the Festival 2018, Glasgow European Championships, Glasgow, UK, 9th August 2018.
Year(s) Of Engagement Activity 2018
 
Description What Keeps You Sharp? - Alan Gow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Presentation on factors related to brain health as part of Brainworks Day (part of the Engaging Libraries project, funded by the Carnegie Trust and the Wellcome Trust), Milngavie, UK, 27th July 2018.
Year(s) Of Engagement Activity 2018
 
Description What's in your head? schools workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact This was a workshop for 9-11 year olds called What's in your head? Staying connected, held between 17th and 19th March 2014. The workshops were attended by around 50 school pupils.

This importantly raised awareness of brain size and the ageing of the brain and mental skills among younger people.
Year(s) Of Engagement Activity 2014
 
Description Women of Scotland Lunch (Shenkin) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact April 2016: Speaker at Women of Scotland Lunch (380 attendees, fundraiser for Music in Hospitals, raised over £23,000)
Year(s) Of Engagement Activity 2016
URL http://www.wosl.co.uk/2016/04/women-of-scotland-lunch-2016-2
 
Description World Economic Forum CCACE Stall 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact CCACE had a stall at the World Economic Forum Global Agenda on Ageing Symposium, held in February 2016 at the British Medical Association building in London. The stall displayed results from our research and included many of our engagement leaflets, books, and other materials such as our 3D-printed brains and computer programmes. A great amount of interest was garnered by the stall, and many contacts among unusual audiences were gained, for example from employees of banks such as Barclay's, who were looking to improve their banking services for older people.
Year(s) Of Engagement Activity 2016
 
Description World Economic Forum lecture 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact This was hosted by the charity Age UK. The members of the World Economic Forums group on ageing met, along with many people from the banking industry. The idea of the two days of meeting was to examine the impact of cognitive ageing on financial decision making by older people. Professor Deary provided an overview lecture, including much of this own research, on what happens to cognitive skills in older age and their implications for financial decision making. His talk was subsequently much discussed over the two days of the meeting and used as essential information for the charity and banking industry to make informed decisions about how to present financial information to older people.
Year(s) Of Engagement Activity 2015
 
Description Yau - Alzheimer's Research UK talk 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Short talk on stress and dementia, organised by the Alzheimer's Society Scotland Research Centre.

There has been no known impact beyond the interest of attendees.
Year(s) Of Engagement Activity 2013
 
Description de Bruin - bilingualism cognitive decline Western Morning News 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Angela de Bruin, Centre PhD student, commented on the connection between bilingualism and cognitive decline in the Western Morning News, 18th August 2014.

This commentary was in the public domain.
Year(s) Of Engagement Activity 2014
 
Description www.ccace.ed.ac.uk 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact The CCACE website (www.ccace.ed.ac.uk) was re-launched in January 2011, with separate sections for different stakeholder audiences and an accessible new media-led front page.

The website has had many thousands of visitors and is appreciated as a vibrant and regularly-updated window for the activities of the Centre.
Year(s) Of Engagement Activity 2010,2011,2012,2013,2014
URL http://www.ccace.ed.ac.uk
 
Description •Careers workshop presentation - Riccardo Marioni 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact • Careers workshop presentation to ~50 postgraduate students taking the UoE MSc in Operational Research (Nov 2018)

Some students were more interested in pursuing a PhD after this talk
Year(s) Of Engagement Activity 2018